TY - JOUR A1 - Kagel, Heike A1 - Jacobs, Hannes A1 - Bier, Frank Fabian A1 - Glökler, Jörn A1 - Frohme, Marcus T1 - A Novel Microtiter Plate Format High Power Open Source LED Array JF - Photonics N2 - Many photochemical or photobiological applications require the use of high power ultraviolet light sources, such as high-pressure mercury arc lamps. In addition, many photo-induced chemical, biochemical and biological applications require either a combinatorial setting or a parallel assay of multiple samples under the same environmental conditions to ensure reproducibility. To achieve this, alternative, controllable light sources, such as ultraviolet light emitting diodes (UV LEDs) with high power and spatial control are required. Preferably, LEDs are arranged in a suitable standardized 96-well microtiter plate format. We designed such an array and established the methods required for heat management and enabling stable, controllable illumination over time. KW - optics KW - photonics KW - light KW - LED array KW - High-power LED KW - 365 nm KW - microtiter plate Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:526-opus4-11307 SN - 2304-6732 VL - 6 IS - 1 ER - TY - CHAP A1 - Heinrich, Moritz A1 - Stollfuss, Carsten A1 - Jacobs, Hannes A1 - Di Vona, Maria Luisa A1 - Pizzoferrato, Roberto A1 - Foitzik, Andreas ED - Stolzenburg, Frieder ED - Reinboth, Christian ED - Lohr, Thomas ED - Vogel, Kathleen T1 - A conductivity-based, batch-optimized system for analyzing the total of carbon parameter in water T2 - NWK 2023 - Tagungsband zur 23. Nachwuchswissenschaftler*innenkonferenz N2 - In cooperation with the company Purification Membranes Analytics GmbH (PMA), a prototype has been developed that analyzes the total organic carbon (TOC) content of water samples based on a complex conductivity measurement. In the process, a batchoptimized system was developed that delivers qualitative results even in highly polluted waters. This method requires small sample volumes and was assembled using an ultrapure water system, a sample mixing system, various electronic control units and a miniTOC system that uses a UV light source to decompose organic carbons and outputs differential values using two conductivity sensors. During the project, a fully automated prototype was developed and is ready for use. In the future, this method could support common methods and lead to more accurate statements on water quality in a cost-effective manner. Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:526-opus4-18598 UR - https://www.hs-harz.de/nwk2023/tagungsband-nwk-2023 UR - https://www.hs-harz.de/dokumente/extern/Forschung/NWK2023/Beitraege/A_conductivity-based__batch-optimized_system_for_analyzing_the_total_of_carbon_parameter_in_water.pdf SN - 2627-5708 N1 - 23. Nachwuchswissenschaftler*innenkonferenz am 31.05. und 01.06. an der Hochschule Harz in Wernigerode SP - 15 EP - 20 PB - Hochschule Harz CY - Wernigerode ER - TY - JOUR A1 - Schattschneider, Christoph A1 - Piontek, Sina A1 - Jacobs, Hannes A1 - Böhme, Andrea A1 - Sirena, Concetta A1 - Foitzik, Andreas T1 - Proof of Principle of Wastewater Treatment using Plasma Discharge to Reduce the Amount of Methylparaben JF - Athens Journal of Sciences N2 - Synthetic substances like many pharmaceuticals, preservatives or other chemical compounds are actually very difficult to handle in sewage treatment. These compounds are very stable in aqueous solution and their degradation reactions are insufficient. Therefore, to eliminate these substances from wastewater additional afford is necessary. Extreme conditions like pH value, redox potential, chemical or physical energy need to be present. With our study we try to show that the use of plasma discharge could be a solution to this problem. Using the example of methylparaben, a preservative, we could show, that the physical energy of plasma discharge is able to initialize the degradation reaction in aqueous environment. The concentration was reduced by up to 70 percent in our setting depending on the treatment duration. Overall, the system showed potential to optimize wastewater treatment. Further examinations are necessary for example regarding undesirable by-products. KW - wastewater treatment KW - plasma discharge KW - high voltage KW - degradation Y1 - 2024 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:526-opus4-18649 SN - 2241-8466 VL - 11 IS - 1 SP - 29 EP - 38 PB - Athens Institute for Education and Research ER - TY - JOUR A1 - Engels, Andreas A1 - Schlegel, Volker A1 - Jacobs, Hannes A1 - Großelindemann, Niklas A1 - Morshed, Md. Niaz A1 - Stenglein, Antonia Sigrid A1 - Bonaiuto, Vincenzo A1 - Foitzik, Andreas T1 - 3d Printer Heads for Extrusion of Biologicals Gels JF - Materials Science Forum N2 - Processing biological materials with 3-dimensional (3D) printers has attracted increasing interest in several research areas. At the same time, off-the-shelf solutions are increasingly available in a wider variety to meet the current market demand. However, most of the available bioprinters are closed source, thus, modifications are quite challenging or require an avoidable consultation process with the manufacturer. Furthermore, the entry prices for basic machines amount to several thousands of euros. Whereas, high-end 3D bio printers with a vast array of features are available for several hundred thousand euros. Due to the immense potential of this tool in the field of biotechnology it is important to extend the availability of this technology for research purposes in terms of adaptability and price. This ongoing work focuses on open-source 3D printer heads with the ability to extrude biological materials. The print heads include several techniques to process low as well as high viscose biomaterials such as agar and gelatin. Additionally, obstacles such as continuous substrate tempering or integration into existing 3D printers are addressed. The work presented is open source and thus freely adaptable to any user’s specific needs. Our goal is to process a diverse range of biomaterials with different print techniques. KW - Bio-Fabrication KW - Bioprinting KW - Open-Source KW - Process Parameter Improvement Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:526-opus4-18773 SN - 0255-5476 SN - 1662-9752 VL - 1016 SP - 435 EP - 439 PB - Trans Tech Publications ER - TY - CHAP A1 - Heinrich, Moritz A1 - Jacobs, Hannes A1 - Di Vona, Maria Luisa A1 - Pizzoferrato, Roberto A1 - Foitzik, Andreas T1 - A Test System for Safely Measurements of Cancer-Inducing UV-C Diodes Produced in a Simple and Cost-Effective Way by Rapid Prototyping T2 - Open Conference Proceedings N2 - New technologies leading to better and more efficient light emitting diodes. The emitted radiation reaches higher energy levels and lower wavelengths especially in the UV-C spectrum. UV-C light has a cancer inducing effect on human cells. Therefore it is necessary to work in a safe way with those devices. This work is focused on an open-source solution for rapid 3D printing of an safe UV-C radiation measuring device. Especially for research groups or universities which can not afford big safety labs. After modeling and printing the prototype, a series of tests has shown the functionality of that UV-C Diode test system. By using black printing filaments and infill rates over 50 %, the transmission of light could be prevented and the system worked well. KW - 3D Printing KW - Rapid Prototyping KW - UV C LED KW - Secure Measurements KW - Validate LED KW - UV-C KW - Radiation Mesaurement Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:526-opus4-17682 VL - 2 SP - 197 EP - 199 PB - TIB Open Publishing ER - TY - CHAP A1 - Millauer, Jan A1 - Jacobs, Hannes A1 - Hein, Jörg-Helge A1 - Brendler, Alina A1 - Minieri, Marilena A1 - Foitzik, Andreas T1 - Validation of an Innovative Passive Collector for Pollutant Analysis in Groundwater T2 - Open Conference Proceedings N2 - A passive pipe sampler device for contaminant analysis in groundwater was developed which create a permanent sampling flow from groundwater and in addition to temperature, conductivity and pressure, now also has room for specific sorbents. The large surface of the adsorber offers more binding surface for the analyte and the constant movement of the sorbent with fresh groundwater also provides homogeneous binding. The spectroscopic analyses at the monitoring site of the pipe passive sampler for groundwater monitoring points enables a measurement-based validation of the sorbent circulation as an alternative to a visual assessment. The optimum pump speed for the sorbens Lewatit® M500 and SR7 was evaluated. The 42mm slim measuring device allows the use in DN50 monitoring well and thus allows the setup of a closer measuring network. Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:526-opus4-17660 VL - 2 SP - 205 EP - 207 PB - TIB Open Publishing ER - TY - CHAP A1 - Hauschultz, Mike A1 - Friedo, Maria H. A1 - Jacobs, Hannes A1 - Lafta, Mohammad A1 - Engels, Andreas A1 - Foitzik, Andreas T1 - Low-cost Pipettierroboter auf Basis einer Portalfräse T1 - Low-Cost Pipetting Robot Based on a Portal Milling Machine T2 - Open Conference Proceedings N2 - Zur Herstellung von langfristig stabilen Metall-Kautschuk-Verbunden sind chemische Haftvermittler notwendig. Nach Auftrag dieser wird Kautschuk mittels Gummispritzgießen auf die metallischen Grundkörper aufgebracht. In Klein- und Kleinstserien kann der Haftvermittler in präzisen Volumina händisch mit Hilfe eines Fluid-Dispensers aufgetragen werden. Allerdings verhindert dies eine Homogenität und Gleichheit der Schichtdicke, wodurch die Zuverlässigkeit und Stärke der Haftung variieren können. Als technische Lösung wurde ein Pipettierroboter avisiert. Mit Hilfe mehrerer mechanischer und elektrischer Adaptionen – so auch einer neuen Steuerungstechnik – wurden verschiedene Fluid-Dispenser auf 3-Achs-Portalfräsen integriert. Somit konnte die volle Funktionsfähigkeit erreicht werden. N2 - Chemical adhesion promoters are necessary for the production of long-term stable metal-rubber composites. After these have been applied, rubber is molded onto the metallic base bodies by rubber injection molding. In (very) small batches, the adhesion promoter can be applied in precise volumes by hand using a fluid dispenser. However, this prevents homogeneity and uniformity of the layer thickness, which can cause variation in the reliability and strength of adhesion. As a technical solution, a pipetting robot has been envisaged. With the aid of several mechanical and electrical adaptations - including a new control technology - various fluid dispensers were integrated on 3-axis portal milling machines. Thus, full functionality could be achieved. Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:526-opus4-17649 VL - 2 SP - 187 EP - 191 PB - TIB Open Publishing ER - TY - CHAP A1 - Friedo, Maria H. A1 - Hauschultz, Mike A1 - Jacobs, Hannes A1 - Lafta, Mohammad A1 - Engels, Andreas A1 - Foitzik, Andreas T1 - Steuerungstechnik für das Auftragen von fluiden Haftvermittlern T1 - Contol Technology for the Application of Fluid Bonding Agents T2 - Open Conference Proceedings N2 - The goal of this project was to enable an automated solution for the application of bonding agents to metallic bodies in the nanoliter range. For the automated application of adhesion promoters, a new control unit based on a mainboard for controlling 3D printers was used, with Marlin serving as the firmware. Adaptations were necessary in the area of motor currents, speeds, acceleration, sensitivity, print bed size and selection of mainboard and display. For the traverse paths, G-code was generated using a program in Python. For homogeneous and uniform wetting, the individual objects to be wetted are approached and the pipetting process is controlled. It was possible to establish the complete functionality. N2 - Das Ziel dieses Projektes war es eine automatisierte Lösung für das Auftragen von Haftvermittlern auf metallische Grundkörper im Nanoliterbereich zu ermöglichen. Für die automatisierte Auftragung von Haftvermittler wurde eine neue Steuerungseinheit auf Grundlage eines Mainboards für die Ansteuerung von 3D-Druckern verwendet, als Firmware diente Marlin. Notwendig waren Anpassungen im Bereich der Motorströme, Geschwindigkeiten, Beschleunigung, Sensitivität, Druckbettgröße und Auswahl von Mainboard und Display. Für die Verfahrwege wurde G-Code mittels eines Programms in Python generiert. Für eine homogene und gleichmäßige Benetzung werden die einzelnen zu benetzenden Objekte angefahren und der Pipettiervorgang gesteuert. Es war möglich die vollständige Funktionsfähigkeit herzustellen. KW - Bonding agent KW - Control technology KW - Marlin Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:526-opus4-17670 VL - 2 SP - 217 EP - 219 PB - TIB Open Publishing ER -