TY - JOUR A1 - Strelkova, Margarita V. A1 - Baranova, Alla M. A1 - Kuhls, Katrin T1 - History of the E.I. Martsinovsky Institute of Medical Parasitology and Tropical Medicine: research on malaria and leishmaniasis JF - História, Ciências, Saúde – Manguinhos N2 - This review presents the 100-year history of the Martsinovsky Institute of Medical Parasitology and Tropical Medicine in Moscow, Russia, starting with its foundation and early activities, and also describes the impact of its leading scientists, some of whom became internationally known. The institute headed a network of nine tropical institutes in the various Soviet republics from the 1920s to 1990. The extensive body of literature on the history and research accomplishments of this institute has mainly been published in Russian; our goal here is to introduce these achievements and this expertise to the international scientific and medical community, focusing on malaria and leishmaniasis and the development of measures to control and monitor these diseases in the USSR. Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:526-opus4-13675 SN - 1678-4758 VL - 27 IS - 4 SP - 1097 EP - 1124 PB - Casa de Oswaldo Cruz, Fundação Oswaldo Cruz ER - TY - JOUR A1 - Kniha, Edwin A1 - Dvořák, Vít A1 - Halada, Petr A1 - Milchram, Markus A1 - Obwaller, Adelheid G. A1 - Kuhls, Katrin A1 - Schlegel, Susanne A1 - Köhsler, Martina A1 - Poeppl, Wolfgang A1 - Bakran-Lebl, Karin A1 - Fuehrer, Hans-Peter A1 - Volfová, Věra A1 - Mooseder, Gerhard A1 - Ivovic, Vladimir A1 - Volf, Petr A1 - Walochnik, Julia T1 - Integrative Approach to Phlebotomus mascittii Grassi, 1908: First Record in Vienna with New Morphological and Molecular Insights JF - Pathogens N2 - Sand flies (Diptera: Psychodidae: Phlebotominae) are blood-feeding insects that transmit the protozoan parasites Leishmania spp. and various arthropod-borne (arbo) viruses. While in Mediterranean parts of Europe the sand fly fauna is diverse, in Central European countries including Austria mainly Phlebotomus mascittii is found, an assumed but unproven vector of Leishmania infantum. To update the currently understudied sand fly distribution in Austria, a sand fly survey was performed and other entomological catches were screened for sand flies. Seven new trapping locations of Ph. mascittii are reported including the first record in Vienna, representing also one of the first findings of this species in a city. Morphological identification, supported by fluorescence microscopy, was confirmed by two molecular approaches, including sequencing and matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) protein profiling. Sand fly occurrence and activity were evaluated based on surveyed locations, habitat requirements and climatic parameters. Moreover, a first comparison of European Ph. mascittii populations was made by two marker genes, cytochrome c oxidase subunit 1 (COI), and cytochrome b (cytb), as well as MALDI-TOF mass spectra. Our study provides new important records of Ph. mascittii in Austria and valuable data for prospective entomological surveys. MALDI-TOF MS protein profiling was shown to be a reliable tool for differentiation between sand fly species. Rising temperatures and globalization demand for regular entomological surveys to monitor changes in species distribution and composition. This is also important with respect to the possible vector competence of Ph. mascittii. KW - Transphlebotomus KW - Central Europe KW - autoimmunofluorescence KW - MALDI-TOF mass spectrometry KW - genotyping KW - leishmaniasis Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:526-opus4-13600 SN - 2076-0817 VL - 9 IS - 12 PB - MDPI ER -