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  <doc>
    <id>1557</id>
    <completedYear>2021</completedYear>
    <publishedYear/>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>4303</pageFirst>
    <pageLast>4312</pageLast>
    <pageNumber/>
    <edition/>
    <issue>6</issue>
    <volume>113</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>1</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Variant expression signatures of microRNAs and protein related to growth in a crossbreed between two strains of Nile tilapia (Oreochromis niloticus)</title>
    <abstract language="eng">Nile tilapia (Oreochromis niloticus) is a species of worldwide importance for aquaculture. A crossbred lineage was developed through introgressive backcross breeding techniques and combines the high growth performance of the Chitralada (CHIT) lwith attractive reddish color of the Red Stirling (REDS) strains. Since the crossbreed has an unknown genetically improved background, the objective of this work was to characterize expression signatures that portray the advantageous phenotype of the crossbreeds. We characterized the microRNA transcriptome by high throughput sequencing (RNA-seq) and the proteome through mass spectrometry (ESI-Q-TOF-MS) and applied bioinformatics for the comparative analysis of such molecular data on the three strains. Crossbreed expressed a distinct set of miRNAs and proteins compared to the parents. They comprised several microRNAs regulate traits of economic interest. Proteomic profiles revealed differences between parental and crossbreed in expression of proteins associated with glycolisis. Distinctive miRNA and protein signatures contribute to the phenotype of crossbreed.</abstract>
    <parentTitle language="eng">Genomics</parentTitle>
    <identifier type="issn">0888-7543</identifier>
    <identifier type="urn">urn:nbn:de:kobv:526-opus4-15571</identifier>
    <enrichment key="opus.import.date">2021-12-13T10:04:26+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">sword</enrichment>
    <enrichment key="opus.import.file">filename=php6hCjR4</enrichment>
    <enrichment key="opus.import.checksum">622accdf5d7d1e40cd721eca2945828a</enrichment>
    <enrichment key="DOI_VoR">https://doi.org/10.1016/j.ygeno.2021.11.008</enrichment>
    <enrichment key="SourceTitle">Herkenhoff, M. E., Bovolenta, L. A., Brödel, O., dos Santos, L. D., de Oliveira, A. C., Chuffa, L. G. A., … Pinhal, D. (2021). Variant expression signatures of microRNAs and protein related to growth in a crossbreed between two strains of Nile tilapia (Oreochromis niloticus). Genomics, 113(6), 4303–4312. doi:10.1016/j.ygeno.2021.11.008</enrichment>
    <licence>Creative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International</licence>
    <author>Marcos Edgar Herkenhoff</author>
    <author>Luiz A. Bovolenta</author>
    <author>Oliver Brödel</author>
    <author>Lucilene Delazari dos Santos</author>
    <author>Arthur C. de Oliveira</author>
    <author>Luiz G.A. Chuffa</author>
    <author>Amanda O. Ribeiro</author>
    <author>Luiz A. Lupi</author>
    <author>Marco A.D. Dias</author>
    <author>Alexandre W.S. Hilsdorf</author>
    <author>Marcus Frohme</author>
    <author>Danillo Pinhal</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Nile tilapia</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>growth</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>RNA-seq</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>miRNA</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>ESI-Q-TOF</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>proteome</value>
    </subject>
    <collection role="ddc" number="570">Biowissenschaften; Biologie</collection>
    <collection role="institutes" number="">Fachbereich Ingenieur- und Naturwissenschaften</collection>
    <collection role="open_access" number="">open_access</collection>
    <collection role="Import" number="import">Import</collection>
    <collection role="green_open_access" number="4">Hybrid Open Access</collection>
    <thesisPublisher>Technische Hochschule Wildau</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-th-wildau/files/1557/1-s2.0-S0888754321003906-main.pdf</file>
  </doc>
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