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<export-example>
  <doc>
    <id>1201</id>
    <completedYear>2019</completedYear>
    <publishedYear/>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>20</pageNumber>
    <edition/>
    <issue/>
    <volume/>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>1</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Re-Emerging Foci of Visceral Leishmaniasis in Armenia – First Molecular Diagnosis of Clinical Samples</title>
    <abstract language="eng">Visceral leishmaniasis (VL) was firstly reported in Armenia in 1913. Following a considerable increase of the number of cases until the mid 1950s, the diseases disappeared after 1969 and re-emerged in 1999. Scientific literature about VL in Armenia  is available only in Russian or Armenian. This paper presents a historical overview about leishmaniasis in Armenia based on this literature as well as an epidemiological update since the re-emergence of the disease. In 1999- 2016, 116 indigenous VL cases were recorded mainly in children in 8 of the 11 districts, however VL is underreported because of lack of trained medical personal and diagnostic facilities. The aim of this work was to apply for the first time molecular diagnosis of VL in Armenia. Out of 25 VL suspected patients, 22 were positive by microscopy and PCR. Genotyping using ITS1-PCR-RFLP and sequencing identified the causative agent of VL in Armenia as Leishmania infantum. The present work is an important step towards the inclusion of molecular techniques in the current diagnosis of VL in Armenia and the establishment of local molecular diagnostic facilities.</abstract>
    <parentTitle language="eng">Parasitology</parentTitle>
    <identifier type="urn">urn:nbn:de:kobv:526-opus4-12018</identifier>
    <identifier type="issn">1469-8161</identifier>
    <enrichment key="SourceTitle">Sukiasyan, A., Keshishyan, A., Manukyan, D., Melik-Andreasyan, G., Atshemyan, L., Apresyan, H., . . . Kuhls, K. (n.d.). Re-Emerging foci of visceral leishmaniasis in Armenia – first molecular diagnosis of clinical samples. Parasitology, 1-8. doi:10.1017/S0031182019000064</enrichment>
    <enrichment key="CopyrightInfo">This article has been published in a revised form in Parasitology [http://doi.org/10.1017/S0031182019000064]. This version is published under a Creative Commons CC-BY-NC-ND. No commercial re-distribution or re-use allowed. Derivative works cannot be distributed. © Katrin Kuhls.</enrichment>
    <enrichment key="DOI_VoR">https://doi.org/10.1017/S0031182019000064</enrichment>
    <licence>Creative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International</licence>
    <author>Anna Sukiasyan</author>
    <author>Ara Keshishyan</author>
    <author>Dezdemonia Manukyan</author>
    <author>Gayane Melik-Andreasyan</author>
    <author>Liana Atshemyan</author>
    <author>Hripsime Apresyan</author>
    <author>Margarita V. Strelkova</author>
    <author>Marcus Frohme</author>
    <author>Sofia Cortes</author>
    <author>Katrin Kuhls</author>
    <collection role="ddc" number="570">Biowissenschaften; Biologie</collection>
    <collection role="institutes" number="">Fachbereich Ingenieur- und Naturwissenschaften</collection>
    <collection role="open_access" number="">open_access</collection>
    <collection role="green_open_access" number="2">Green Open Access</collection>
    <thesisPublisher>Technische Hochschule Wildau</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-th-wildau/files/1201/Sukiasyan_et_al_2019_accepted_version.pdf</file>
  </doc>
  <doc>
    <id>1400</id>
    <completedYear>2021</completedYear>
    <publishedYear/>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>e0009288</pageFirst>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue>4</issue>
    <volume>15</volume>
    <type>article</type>
    <publisherName>Public Library of Science (PLoS)</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>1</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Microsatellite based molecular epidemiology of Leishmania infantum from re-emerging foci of visceral leishmaniasis in Armenia and pilot risk assessment by ecological niche modeling</title>
    <abstract language="eng">Leishmaniasis is a vector-borne disease caused by protozoan parasites of the genus Leishmania. In Armenia visceral leishmaniasis (VL) is re-emerging since 1999 after a long break of 30 years, with 167 cases recorded until 2019. Molecular diagnosis of VL was implemented only in 2016, and the causative agent was identified as L. infantum. In the present study we expanded the investigation of the causative agent to a characterization at strain level and the identification of its phylogenetic position among the L. infantum genotypes circulating worldwide. This is the first study addressing genetic diversity and population structure of L. infantum in Armenia and in Transcaucasia. Armenia is an extremely interesting region due to its bio-geographic specificities e.g. the high number of different climates in this small mountainous country and the observed high diversity of sand fly species, part of which occurring in very high altitudes. Ecological niche modeling based on registered VL cases and sand fly vectors collected in active VL foci revealed that the risk of further spread of VL is very high due to climate change. Studies of this region should be expanded to enable targeted control measures.</abstract>
    <parentTitle language="eng">PLoS Neglected Tropical Diseases</parentTitle>
    <identifier type="issn">1935-2735</identifier>
    <identifier type="urn">urn:nbn:de:kobv:526-opus4-14004</identifier>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="SourceTitle">Kuhls K, Moskalenko O, Sukiasyan A, Manukyan D, Melik-Andreasyan G, Atshemyan L, et al. (2021) Microsatellite based molecular epidemiology of Leishmania infantum from re-emerging foci of visceral leishmaniasis in Armenia and pilot risk assessment by ecological niche modeling. PLoS Negl Trop Dis 15(4): e0009288. https://doi.org/10.1371/journal.pntd.0009288</enrichment>
    <enrichment key="DOI_VoR">https://doi.org/10.1371/journal.pntd.0009288</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Katrin Kuhls</author>
    <author>Olga Moskalenko</author>
    <author>Anna Sukiasyan</author>
    <author>Dezdemonia Manukyan</author>
    <author>Gayane Melik-Andreasyan</author>
    <author>Liana Atshemyan</author>
    <author>Hripsime Apresyan</author>
    <author>Margarita V. Strelkova</author>
    <author>Anja Jaeschke</author>
    <author>Ralf Wieland</author>
    <author>Marcus Frohme</author>
    <author>Sofia Cortes</author>
    <author>Ara Keshishyan</author>
    <collection role="ddc" number="570">Biowissenschaften; Biologie</collection>
    <collection role="institutes" number="">Fachbereich Ingenieur- und Naturwissenschaften</collection>
    <collection role="open_access" number="">open_access</collection>
    <collection role="green_open_access" number="1">Gold Open Access</collection>
    <thesisPublisher>Technische Hochschule Wildau</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-th-wildau/files/1400/journal.pntd.0009288.pdf</file>
  </doc>
</export-example>
