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  <doc>
    <id>1477</id>
    <completedYear>2019</completedYear>
    <publishedYear/>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>1</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">LED-based portable light source for photodynamic therapy</title>
    <abstract language="eng">Photodynamic therapy (PDT) employs light activation of tissue-localized photosensitizer in an oxygen-dependent process which initiates oxidative stress, inflammation, and cell death. Laser systems, which are mostly used in PDT as light sources can be costly and oversized. light-emitting diodes (LEDs) equipment has a high potential to simplify technical part of phototriggered therapies and to reduce its costs. We develop the LED-based system that includes the control and irradiation units. The system provides the same power density at any irradiation point. Among the advantages of the device is a possibility to change the irradiation area and tune the irradiation dose. PDT experiments with cancer cells in vitro treated with two different photosensitizers demonstrated a possibility to use the developed LED-based system as a low-cost light source in PDT.</abstract>
    <identifier type="urn">urn:nbn:de:kobv:526-opus4-14778</identifier>
    <enrichment key="opus.import.date">2021-08-26T11:19:53+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">sword</enrichment>
    <enrichment key="opus.import.file">filename=phpCgvAlh</enrichment>
    <enrichment key="opus.import.checksum">c2d415e2348cf5f248f3ea95b8aac99c</enrichment>
    <enrichment key="DOI_VoR">https://doi.org/10.1117/12.2541774</enrichment>
    <enrichment key="SourceTitle">O. Chepurna, A. Grebinyk, Yu. Petrushko, S. Prylutska, S. Grebinyk, V. M. Yashchuk, O. Matyshevska, U. Ritter, T. Dandekar, M. Frohme, J. Qu, and T. Y. Ohulchanskyy, "LED-based portable light source for photodynamic therapy", Proc. SPIE 11190, Optics in Health Care and Biomedical Optics IX, 111901A (20 November 2019); https://doi.org/10.1117/12.2541774</enrichment>
    <enrichment key="CopyrightInfo">Copyright 2019 Society of Photo-Optical Instrumentation Engineers (SPIE). One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.</enrichment>
    <licence>Das Dokument ist urheberrechtlich geschützt.</licence>
    <author>Oksana Chepurna</author>
    <author>Anna Grebinyk</author>
    <author>Yulia Petrushko</author>
    <author>Svitlana Prylutska</author>
    <author>Sergii Grebinyk</author>
    <author>Valeriy Yashchuk</author>
    <author>Olga Matyshevska</author>
    <author>Uwe Ritter</author>
    <author>Thomas Dandekar</author>
    <author>Marcus Frohme</author>
    <author>Junle Qu</author>
    <author>Tymish Y. Ohulchanskyy</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>light source</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>high power single chip LED</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>photodynamic therapy</value>
    </subject>
    <collection role="ddc" number="621">Angewandte Physik</collection>
    <collection role="institutes" number="">Fachbereich Ingenieur- und Naturwissenschaften</collection>
    <collection role="open_access" number="">open_access</collection>
    <collection role="Import" number="import">Import</collection>
    <collection role="green_open_access" number="2">Green Open Access</collection>
    <thesisPublisher>Technische Hochschule Wildau</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-th-wildau/files/1477/111901A.pdf</file>
  </doc>
</export-example>
