<?xml version="1.0" encoding="utf-8"?>
<export-example>
  <doc>
    <id>624</id>
    <completedYear>2007</completedYear>
    <publishedYear/>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>12</pageNumber>
    <edition/>
    <issue>48</issue>
    <volume>7</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>1</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">One-step selection of Vaccinia virus-binding DNA aptamers by MonoLEX</title>
    <abstract language="eng">As a new class of therapeutic and diagnostic reagents, more than fifteen years ago RNA and DNA aptamers were identified as binding molecules to numerous small compounds, proteins and rarely even to complete pathogen particles. Most aptamers were isolated from complex libraries of synthetic nucleic acids by a process termed SELEX based on several selection and amplification steps. Here we report the application of a new one-step selection method (MonoLEX) to acquire high-affinity DNA aptamers binding Vaccinia virus used as a model organism for complex target structures.</abstract>
    <parentTitle language="eng">BMC Biotechnology</parentTitle>
    <identifier type="issn">1472-6750</identifier>
    <identifier type="urn">urn:nbn:de:kobv:526-opus4-6246</identifier>
    <enrichment key="SourceTitle">A. Nitsche et al. One-step selection of Vaccinia virus-binding DNA aptamers by MonoLEX. BMC Biotechnology 2007, 7:48 doi:10.1186/1472-6750-7-48</enrichment>
    <enrichment key="DOI_VoR">https://doi.org/10.1186/1472-6750-7-48</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 2.0 Generic</licence>
    <author>Andreas Nitsche</author>
    <author>Andreas Kurth</author>
    <author>Anna Dunkhorst</author>
    <author>Oliver Pänke</author>
    <author>Hendrik Sielaff</author>
    <author>Wolfgang Junge</author>
    <author>Doreen Muth</author>
    <author>Frieder W. Scheller</author>
    <author>Walter Stöcklein</author>
    <author>Claudia Dahmen</author>
    <author>Georg Pauli</author>
    <author>Andreas Kage</author>
    <collection role="ddc" number="570">Biowissenschaften; Biologie</collection>
    <collection role="institutes" number="">Fachbereich Ingenieurwesen / Wirtschaftsingenieurwesen (bis 8/2014)</collection>
    <collection role="open_access" number="">open_access</collection>
    <collection role="green_open_access" number="1">Gold Open Access</collection>
    <thesisPublisher>Technische Hochschule Wildau</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-th-wildau/files/624/2F1472-6750-7-48.pdf</file>
  </doc>
</export-example>
