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<export-example>
  <doc>
    <id>585</id>
    <completedYear>2016</completedYear>
    <publishedYear/>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>40</pageNumber>
    <edition/>
    <issue>3</issue>
    <volume>10</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>1</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">A Historical Overview of the Classification, Evolution, and Dispersion of Leishmania Parasites and Sandflies</title>
    <abstract language="eng">The aim of this study is to describe the major evolutionary historical events among Leishmania, sandflies, and the associated animal reservoirs in detail, in accordance with the geographical evolution of the Earth, which has not been previously discussed on a large scale.</abstract>
    <parentTitle language="eng">PLoS Neglected Tropical Diseases</parentTitle>
    <identifier type="issn">1935-2735</identifier>
    <identifier type="urn">urn:nbn:de:kobv:526-opus4-5853</identifier>
    <enrichment key="SourceTitle">Akhoundi M, Kuhls K, Cannet A, Votýpka J, Marty P, Delaunay P, et al. (2016) A Historical Overview of the Classification, Evolution, and Dispersion of Leishmania Parasites and Sandflies. PLoS Negl Trop Dis 10(3): e0004349. doi:10.1371/journal.pntd.0004349</enrichment>
    <enrichment key="BibtexRecord">https://doi.org/10.1371/journal.pntd.0004349</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Mohammad Akhoundi</author>
    <author>Katrin Kuhls</author>
    <author>Arnaud Cannet</author>
    <author>Jan Votýpka</author>
    <author>Pierre Marty</author>
    <author>Pascal Delaunay</author>
    <author>Denis Sereno</author>
    <collection role="ddc" number="570">Biowissenschaften; Biologie</collection>
    <collection role="institutes" number="">Fachbereich Ingenieur- und Naturwissenschaften</collection>
    <collection role="open_access" number="">open_access</collection>
    <collection role="green_open_access" number="1">Gold Open Access</collection>
    <thesisPublisher>Technische Hochschule Wildau</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-th-wildau/files/585/pntd.0004349.pdf</file>
  </doc>
  <doc>
    <id>990</id>
    <completedYear>2017</completedYear>
    <publishedYear/>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1</pageFirst>
    <pageLast>29</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>57</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>1</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Leishmania infections: Molecular targets and diagnosis</title>
    <abstract language="eng">Progress in the diagnosis of leishmaniases depends on the development of effective methods and the discovery of suitable biomarkers. We propose firstly an update classification of Leishmania species and their synonymies. We demonstrate a global map highlighting the geography of known endemic Leishmania species pathogenic to humans. We summarize a complete list of techniques currently in use and discuss their advantages and limitations. The available data highlights the benefits of molecular markers in terms of their sensitivity and specificity to quantify variation from the subgeneric level to species complexes, (sub) species within complexes, and individual populations and infection foci. Each DNA-based detection method is supplied with a comprehensive description of markers and primers and proposal for a classification based on the role of each target and primer in the detection, identification and quantification of leishmaniasis infection. We outline a genome-wide map of genes informative for diagnosis that have been used for Leishmania genotyping. Furthermore, we propose a classification method based on the suitability of well-studied molecular markers for typing the 21 known Leishmania species pathogenic to humans. This can be applied to newly discovered species and to hybrid strains originating from inter-species crosses. Developing more effective and sensitive diagnostic methods and biomarkers is vital for enhancing Leishmania infection control programs.</abstract>
    <parentTitle language="eng">Molecular Aspects of Medicine</parentTitle>
    <identifier type="issn">0098-2997</identifier>
    <identifier type="urn">urn:nbn:de:kobv:526-opus4-9908</identifier>
    <enrichment key="SourceTitle">M. Akhoundi et al., Leishmania infections: Molecular targets and diagnosis, In Molecular Aspects of Medicine, Volume 57, 2017, Pages 1-29, ISSN 0098-2997, https://doi.org/10.1016/j.mam.2016.11.012.</enrichment>
    <enrichment key="DOI_VoR">https://doi.org/10.1016/j.mam.2016.11.012</enrichment>
    <licence>Creative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International</licence>
    <author>Mohammad Akhoundi</author>
    <author>Tim Downing</author>
    <author>Jan Votýpka</author>
    <author>Katrin Kuhls</author>
    <author>Julius Lukeš</author>
    <author>Arnaud Cannet</author>
    <author>Christophe Ravel</author>
    <author>Pierre Marty</author>
    <author>Pascal Delaunay</author>
    <author>Mohamed Kasbari</author>
    <author>Bruno Granouillac</author>
    <author>Luigi Gradoni</author>
    <author>Denis Sereno</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>molecular marker</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>diagnostic method</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>hybrid strain</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>sympatric species</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>genome-wide map</value>
    </subject>
    <collection role="ddc" number="570">Biowissenschaften; Biologie</collection>
    <collection role="institutes" number="">Fachbereich Ingenieur- und Naturwissenschaften</collection>
    <collection role="open_access" number="">open_access</collection>
    <collection role="green_open_access" number="4">Hybrid Open Access</collection>
    <thesisPublisher>Technische Hochschule Wildau</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-th-wildau/files/990/1-s2.0-S0098299716300450-main.pdf</file>
  </doc>
</export-example>
