<?xml version="1.0" encoding="utf-8"?>
<export-example>
  <doc>
    <id>1868</id>
    <completedYear>2018</completedYear>
    <publishedYear/>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>2522</pageFirst>
    <pageLast>2527</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>941</volume>
    <type>article</type>
    <publisherName>Trans Tech Publications</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>1</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Development of a Smartphone Based Reader for the Quantitative Analysis of Lateral Flow Assays</title>
    <abstract language="eng">Smartphones are developing into all-purposes devices. In the present work, the employment/application of smartphones as medical devices in home care and point-of-care (POC) diagnostics are investigated in the analysis of Lateral Flow Assays (LFA). A smartphone-based LFA reader was developed for the quantitative analysis of D-Dimer – a biomarker indicating e.g. thrombotic event or danger of embolism.The proof-of-concept has been shown with multiple smartphones in establishing: (I) Optimal dimensions of the LFA cell of 72.11mm distance of smartphone to D-Dimer test leading to a coefficients of variances (CV) between 0.8% and 4.2%. (II) Inter-device investigations: CVs around 13.5%; a limit of detection (LOD) of 100ng/ml (DDU) D-Dimer. (III) Inter-smartphone investigations: CV about 16%, a limit of detection (LOD) at 66.4ng/ml (DDU). (IV) Calibrations: CV and LOD of three smartphones are comparable to the commercial available LFA reader. Further development to put the multiple smartphone-based LFA reader on the market.</abstract>
    <parentTitle language="eng">Materials Science Forum</parentTitle>
    <identifier type="issn">0255-5476</identifier>
    <identifier type="issn">1662-9752</identifier>
    <identifier type="urn">urn:nbn:de:kobv:526-opus4-18688</identifier>
    <enrichment key="opus.import.date">2024-03-04T09:53:35+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">sword</enrichment>
    <enrichment key="DOI_VoR">https://doi.org/10.4028/www.scientific.net/MSF.941.2522</enrichment>
    <enrichment key="SourceTitle">Schneider, S., Selig, M., Keil, V., Lehmann, M., Foitzik, A. H., Casalboni, M., &amp; Richetta, M. (2018). Development of a Smartphone Based Reader for the Quantitative Analysis of Lateral Flow Assays. Materials Science Forum, 941, 2522–2527. https://doi.org/10.4028/www.scientific.net/msf.941.2522</enrichment>
    <licence>DFG-geförderte Allianz- bzw. Nationallizenz</licence>
    <author>Sylvio Schneider</author>
    <author>Martina Selig</author>
    <author>Verena Keil</author>
    <author>Matthias Lehmann</author>
    <author>Andreas Foitzik</author>
    <author>Mauro Casalboni</author>
    <author>Maria Richetta</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>APP</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>home care</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>lateral flow assay</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>LFA reader</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>point-of-care (POC)</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>quantitative analysis</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>smartphone</value>
    </subject>
    <collection role="ddc" number="610">Medizin und Gesundheit</collection>
    <collection role="ddc" number="620">Ingenieurwissenschaften und zugeordnete Tätigkeiten</collection>
    <collection role="institutes" number="">Fachbereich Ingenieur- und Naturwissenschaften</collection>
    <collection role="open_access" number="">open_access</collection>
    <collection role="Import" number="import">Import</collection>
    <collection role="green_open_access" number="2">Green Open Access</collection>
    <thesisPublisher>Technische Hochschule Wildau</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-th-wildau/files/1868/MSF.941.2522.pdf</file>
  </doc>
</export-example>
