<?xml version="1.0" encoding="utf-8"?>
<export-example>
  <doc>
    <id>981</id>
    <completedYear>2017</completedYear>
    <publishedYear/>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue>17</issue>
    <volume>18</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>1</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Identification of G-quadruplex structures that possess transcriptional regulating functions in the Dele and Cdc6 CpG islands</title>
    <abstract language="eng">G-quadruplex is a DNA secondary structure that has been shown to play an important role in biological systems. In a previous study, we identified 1998 G-quadruplex-forming sequences using a mouse CpG islands DNA microarray with a fluorescent-labeled G-quadruplex ligand. Among these putative G-quadruplex-forming sequences, G-quadruplex formation was verified for 10 randomly selected sequences by CD spectroscopy and DMS footprinting analysis. In this study, the biological function of the 10 G-quadruplex-forming sequences in the transcriptional regulation has been analyzed using a reporter assay.</abstract>
    <parentTitle language="eng">BMC Molecular Biology</parentTitle>
    <identifier type="issn">1471-2199</identifier>
    <identifier type="urn">urn:nbn:de:kobv:526-opus4-9811</identifier>
    <enrichment key="SourceTitle">Bay et al. BMC Molecular Biol (2017) 18:17. DOI 10.1186/s12867-017-0094-z</enrichment>
    <enrichment key="DOI_VoR">https://doi.org/10.1186/s12867-017-0094-z</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Daniyah H. Bay</author>
    <author>Annika Busch</author>
    <author>Fred Lisdat</author>
    <author>Keisuke Iida</author>
    <author>Kazunori Ikebukuro</author>
    <author>Kazuo Nagasawa</author>
    <author>Isao Karube</author>
    <author>Wataru Yoshida</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Cdc6</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Dele</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>G-quadruplex</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>transcriptional regulation</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>7OTD</value>
    </subject>
    <collection role="ddc" number="570">Biowissenschaften; Biologie</collection>
    <collection role="institutes" number="">Fachbereich Ingenieur- und Naturwissenschaften</collection>
    <collection role="open_access" number="">open_access</collection>
    <collection role="green_open_access" number="1">Gold Open Access</collection>
    <thesisPublisher>Technische Hochschule Wildau</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-th-wildau/files/981/s12867-017-0094-z.pdf</file>
  </doc>
</export-example>
