<?xml version="1.0" encoding="utf-8"?>
<export-example>
  <doc>
    <id>1999</id>
    <completedYear>2010</completedYear>
    <publishedYear/>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>423</pageFirst>
    <pageLast>430</pageLast>
    <pageNumber/>
    <edition/>
    <issue>4</issue>
    <volume>15</volume>
    <type>article</type>
    <publisherName>Springer</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>1</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Stress response in tardigrades: differential gene expression of molecular chaperones</title>
    <abstract language="eng">Semi-terrestrial tardigrades exhibit a remarkable tolerance to desiccation by entering a state called anhydrobiosis. In this state, they show a strong resistance against several kinds of physical extremes. Because of the probable importance of stress proteins during the phases of dehydration and rehydration, the relative abundance of transcripts coding for two α-crystallin heat-shock proteins (Mt-sHsp17.2 and Mt-sHsp19.5), as well for the heat-shock proteins Mt-sHsp10, Mt-Hsp60, Mt-Hsp70 and Mt-Hsp90, were analysed in active and anhydrobiotic tardigrades of the species Milnesium tardigradum. They were also analysed in the transitional stage (I) of dehydration, the transitional stage (II) of rehydration and in heat-shocked specimens. A variable pattern of expression was detected, with most candidates being downregulated. Gene transcripts of one Mt-hsp70 isoform in the transitional stage I and Mt-hsp90 in the anhydrobiotic stage were significantly upregulated. A high gene expression (778.6-fold) was found for the small α-crystallin heat-shock protein gene Mt-sHsp17.2 after heat shock. We discuss the limited role of the stress-gene expression in the transitional stages between the active and anhydrobiotic tardigrades and other mechanisms which allow tardigrades to survive desiccation.</abstract>
    <parentTitle language="eng">Cell Stress and Chaperones</parentTitle>
    <identifier type="urn">urn:nbn:de:kobv:526-opus4-19994</identifier>
    <enrichment key="opus.import.date">2025-02-13T07:52:45+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">sword</enrichment>
    <enrichment key="DOI_VoR">https://doi.org/10.1007/s12192-009-0158-1</enrichment>
    <enrichment key="SourceTitle">Reuner, A., Hengherr, S., Mali, B., Förster, F., Arndt, D., Reinhardt, R., … Schill, R. O. (2010). Stress response in tardigrades: differential gene expression of molecular chaperones. Cell Stress and Chaperones, 15(4), 423–430. doi:10.1007/s12192-009-0158-1</enrichment>
    <enrichment key="opus.doi.autoCreate">false</enrichment>
    <enrichment key="opus.urn.autoCreate">true</enrichment>
    <licence>Creative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International</licence>
    <author>Andy Reuner</author>
    <author>Steffen Hengherr</author>
    <author>Brahim Mali</author>
    <author>Frank Förster</author>
    <author>Detlev Arndt</author>
    <author>Richard Reinhardt</author>
    <author>Thomas Dandekar</author>
    <author>Marcus Frohme</author>
    <author>Franz Brümmer</author>
    <author>Ralph O. Schill</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>alpha-crystallin protein</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>anhydrobiosis</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>cryptobiosis</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>heat-shock protein</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>tardigrada</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Milnesium tardigradum</value>
    </subject>
    <collection role="ddc" number="571">Physiologie und verwandte Themen</collection>
    <collection role="ddc" number="592">Evertebrata (Wirbellose)</collection>
    <collection role="institutes" number="">Fachbereich Ingenieurwesen / Wirtschaftsingenieurwesen (bis 8/2014)</collection>
    <collection role="open_access" number="">open_access</collection>
    <collection role="Import" number="import">Import</collection>
    <thesisPublisher>Technische Hochschule Wildau</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-th-wildau/files/1999/1-s2.0-S1355814523005679-main.pdf</file>
  </doc>
</export-example>
