@inproceedings{Roesch1994, author = {R{\"o}sch, Olga}, title = {Deutsch-Deutsch-Deutsches : Rußlanddeutsche in Berlin}, series = {Deutsch in Osteuropa : ein Tagungsbericht}, booktitle = {Deutsch in Osteuropa : ein Tagungsbericht}, editor = {R{\"o}sch, Olga}, publisher = {PHVT, Provinciale Hogeschool voor Vertalers en Tolken}, address = {Gent}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-12257}, pages = {43 -- 68}, year = {1994}, abstract = {Die vereinigte, aber noch nicht v{\"o}llig geinte Berlin ist neben den Problemen des deutsch-deutschen Zusammenwachsens auch mit der Integration eines bemerkbaren Migrantenstroms konfrontiert. Einen nicht geringen Teil der neuen Zuwanderer machen die in der Stadt vor kurzem noch wenig bekannten Rußlanddeutschen aus. Ihre wunschgem{\"a}ße Zuordnung zum deutschen Kulturkreis ist f{\"u}r einen erheblichen Teil der Berliner problematisch, denn vor allem die sprachlichen Differenzen bis Defizite bei Aussiedlern in bezug auf das Hochdeutsche indizieren, daß es andere, also "fremde" Deutsche sind. Den Aussiedlern f{\"a}llt es ihrerseits nicht leicht, sich sowohl in der Variet{\"a}ten des Deutschen als auch in den beiden deutschen Identit{\"a}ten zurechtzufinden und dabei mit dem Wandlungen ihrer eigenen deutschen - ethnischen, kulturellen und sprachlichen - Selbsverst{\"a}ndnissen klarzukommen.}, language = {de} } @inproceedings{Roesch1991, author = {R{\"o}sch, Olga}, title = {Gibt es ein Medium im Deutschen der Gegenwart?}, series = {Neue Fragen der Linguistik}, booktitle = {Neue Fragen der Linguistik}, editor = {R{\"o}sch, Olga}, publisher = {Niemeyer}, address = {T{\"u}bingen}, isbn = {3-484-30270-4}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-12265}, pages = {253 -- 261}, year = {1991}, abstract = {Das deutsche verbale Genussystem ist in der Grammatikschreibung zweigliedrig. Den grammatischen Verbformen Aktiv und Passiv werden entsprechend aktivische und passivische Bedeutungen zugeordnet, und somit gelten die semantischen Kategorien Aktiv und Passiv im Gegenwartdeutsch als grammatikalisiert. Der semantischen Kategorie Medium entsprechen im Deutschen keine grammatischen Formparadigmen. Aber auch die Darstellungen des semantischen Begriffes Medium selbst werden in der Literatur eher universalgrammatisch und im engeren Sinne sogar universalsemantisch als einzelsprachlich verstanden. In meiner Untersuchung geht es jedoch nicht prim{\"a}r um das Verst{\"a}ndnis des Mediums, sondern um das Verst{\"a}ndnis einer bestimmten Konstruktion, die einige Ber{\"u}hrungspunkte mit dem fr{\"u}heren Medium aufweist. Die Rede ist von einer formal gekennzeichneten Klasse der Funktionsverbgef{\"u}ge (FVG), die vielfach als passivische bzw. passivwertige (pw) FVG bezeichnet werden.}, language = {de} } @article{HornemannSinningCortesetal.2017, author = {Hornemann, Andrea and Sinning, Denise and Cortes, Sofia and Campino, Lenea and Emmer, Peggy and Kuhls, Katrin and Ulm, Gerhard and Frohme, Marcus and Beckhoff, Burkhard}, title = {A pilot study on fingerprinting Leishmania species from the Old World using Fourier transform infrared spectroscopy}, series = {Analytical and Bioanalytical Chemistry}, journal = {Analytical and Bioanalytical Chemistry}, issn = {1432-1130}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-10080}, year = {2017}, abstract = {Leishmania species are protozoan parasites and the causative agents of leishmaniasis, a vector borne disease that imposes a large health burden on individuals living mainly in tropical and subtropical regions. Different Leishmania species are responsible for the distinct clinical patterns, such as cutaneous, mucocutaneous, and visceral leishmaniasis, with the latter being potentially fatal if left untreated. For this reason, it is important to perform correct species identification and differentiation. Fourier transform infrared spectroscopy (FTIR) is an analytical spectroscopic technique increasingly being used as a potential tool for identification of microorganisms for diagnostic purposes. By employing mid-infrared (MIR) spectral data, it is not only possible to assess the chemical structures but also to achieve differentiation supported by multivariate statistic analysis. This work comprises a pilot study on differentiation of Leishmania species of the Old World (L. major, L. tropica, L. infantum, and L. donovani) as well as hybrids of distinct species by using vibrational spectroscopic fingerprints. Films of intact Leishmania parasites and their deoxyribonucleic acid (DNA) were characterized comparatively with respect to their biochemical nature and MIR spectral patterns. The strains' hyperspectral datasets were multivariately examined by means of variance-based principal components analysis (PCA) and distance-based hierarchical cluster analysis (HCA). With the implementation of MIR spectral datasets we show that a phenotypic differentiation of Leishmania at species and intra-species level is feasible. Thus, FTIR spectroscopy can be further exploited for building up spectral databases of Leishmania parasites in view of high-throughput analysis of clinical specimens.}, language = {en} } @article{LuxEdlingSiemrothetal.2018, author = {Lux, Helge and Edling, Matthias and Siemroth, Peter and Schrader, Sigurd}, title = {Fast and Cost-Effective Synthesis of High-Quality Graphene on Copper Foils Using High-Current Arc Evaporation}, series = {Materials}, volume = {11}, journal = {Materials}, number = {5}, issn = {1996-1944}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-10359}, pages = {1 -- 10}, year = {2018}, abstract = {In this paper, we present an innovative and ultra-fast process for the deposition of high-quality graphene on different metal foils and thin metal films. The graphene layer can be homogeneously deposited in only 30 s process time. Due to the weak adhesion to the substrate material, the monolayer graphene is easy to transfer using the established processes. For the production, we use magnetic filtered high-current arc evaporation (Φ-HCA) with a solid, graphitic carbon source. This ultra-fast growth process can pave the way towards a cost-effective graphene synthesis for the mass production e.g., in a roll-to-roll process, avoiding time consuming established processes.}, language = {en} } @article{GrebinykGrebinykPrylutskaetal.2018, author = {Grebinyk, Anna and Grebinyk, Sergii and Prylutska, Svitlana and Ritter, Uwe and Matyshevska, Olga and Dandekar, Thomas and Frohme, Marcus}, title = {HPLC-ESI-MS method for C60 fullerene mitochondrial content quantification}, series = {Data in Brief}, volume = {19}, journal = {Data in Brief}, issn = {2352-3409}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-10368}, pages = {2047 -- 2052}, year = {2018}, abstract = {The presented dataset describes the quantification of carbon nanoparticle C60 fullerene accumulated in mitochondria of human leukemic cells treated with nanostructure. Firstly, the high performance liquid chromatography-electro spray ionization-mass spectrometry (HPLC-ESI-MS) method was developed for quantitative analysis of pristine C60 fullerene. Then, human leukemic cells were incubated with C60 fullerene, homogenized and subjected to the differential centrifugation to retrieve mitochondrial fraction. The C60 fullerene content was quantified by HPLC-ESI-MS in extracts of cellular fractions. This data article refers to the research article "C60 Fullerene Accumulation in Human Leukemic Cells and Perspectives of LED-mediated Photodynamic Therapy" by Grebinyk et al.}, language = {en} } @article{RoeschTolkiehn2018, author = {R{\"o}sch, Olga and Tolkiehn, G{\"u}nter-Ulrich}, title = {Zum Diskurs {\"u}ber die Sprache in der Wissenschaftskommunikation}, series = {Die neue Hochschule : DNH}, journal = {Die neue Hochschule : DNH}, number = {4}, issn = {0340-448X}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-10465}, pages = {26 -- 29}, year = {2018}, abstract = {Der Diskurs {\"u}ber die Wissenschaftssprache darf nicht von außerwissenschaftlichen Interessen bestimmt werden. Er muss in den Bereich der Wissenschaft zur{\"u}ckgeholt und dort freiheitlich mit wissenschaftlicher Rationalit{\"a}t gef{\"u}hrt werden.}, language = {de} } @article{FischbachFrohmeGloekler2017, author = {Fischbach, Jens and Frohme, Marcus and Gl{\"o}kler, J{\"o}rn}, title = {Hinge-initiated Primer-dependent Amplification of Nucleic Acids (HIP) - A New Versatile Isothermal Amplification Method}, series = {Scientific Reports}, volume = {7}, journal = {Scientific Reports}, issn = {2045-2322}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-9824}, year = {2017}, abstract = {The growing demand for cost-effective nucleic acid detection assays leads to an increasing number of different isothermal amplification reaction methods. However, all of the most efficient methods suffer from highly complex assay conditions due to the use of complicated primer sets and/or auxiliary enzymes. The present study describes the application of a new linker moiety that can be incorporated between a primer and a secondary target binding site which can act both as a block to polymerase extension as well as a hinge for refolding. This novel "hinge-primer" approach results in an efficient regeneration of the primer binding site and thus improves the strand-displacement and amplification process under isothermal conditions. Our investigations revealed that the reaction with forward and reverse hinge-primer including an abasic site is very efficient. The assay complexity can be reduced by combining the hinge-primer with a corresponding linear primer. Furthermore, the reaction speed can be increased by reducing the length of the amplified target sequence. We tested the sensitivity down to 104 copies and found a linear correlation between reaction time and input copy number. Our approach overcomes the usually cumbersome primer-design and extends the range of isothermal amplification methods using a polymerase with strand-displacement activity.}, language = {en} } @incollection{MarcLiebchen2017, author = {Marc, Goerigk and Liebchen, Christian}, title = {An Improved Algorithm for the Periodic Timetabling Problem}, series = {17th Workshop on Algorithmic Approaches for Transportation Modelling, Optimization, and Systems (ATMOS 2017)}, booktitle = {17th Workshop on Algorithmic Approaches for Transportation Modelling, Optimization, and Systems (ATMOS 2017)}, editor = {D'Angelo, Gianlorenzo and Dollevoet, Twan}, publisher = {Schloss Dagstuhl / Leibniz-Zentrum f{\"u}r Informatik}, address = {Dagstuhl}, isbn = {978-3-95977-042-2}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-9899}, publisher = {Technische Hochschule Wildau}, pages = {12:1 -- 12:14}, year = {2017}, abstract = {We consider the computation of periodic timetables, which is a key task in the service design process of public transportation companies. We propose a new approach for solving the periodic timetable optimisation problem. It consists of a (partially) heuristic network aggregation to reduce the problem size and make it accessible to standard mixed-integer programming (MIP) solvers. We alternate the invocation of a MIP solver with the well-known problem specific modulo network simplex heuristic (ModSim). This iterative approach helps the ModSim-method to overcome local minima efficiently, and provides the MIP solver with better initial solutions. Our computational experiments are based on the 16 railway instances of the PESPlib, which is the only currently available collection of periodic event scheduling problem instances. For each of these instances, we are able to reduce the objective values of previously best known solutions by at least 10.0\%, and up to 22.8\% with our iterative combined method.}, language = {en} } @article{KarakuşNasereddinOnayetal.2017, author = {Karaku{\c{s}}, Mehmet and Nasereddin, Abed and Onay, H{\"u}seyin and Karaca, Emin and {\"O}zkeklik{\c{c}}i, Ahmet and Jaffe, Charles L. and Kuhls, Katrin and {\"O}zbilgin, Ahmet and Ertabaklar, Hatice and Demir, Samiye and {\"O}zbel, Yusuf and T{\"o}z, Seray}, title = {Epidemiological analysis of Leishmania tropica strains and giemsa-stained smears from Syrian and Turkish leishmaniasis patients using multilocus microsatellite typing (MLMT)}, series = {PLoS Neglected Tropical Diseases}, volume = {11}, journal = {PLoS Neglected Tropical Diseases}, number = {4}, issn = {1935-2735}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-9313}, pages = {12}, year = {2017}, abstract = {Turkey is located in an important geographical location, in terms of the epidemiology of vector-borne diseases, linking Asia and Europe. Cutaneous leishmaniasis (CL) is one of the endemic diseases in a Turkey and according to the Ministry Health of Turkey, 45\% of CL patients originate from Şanl{\i}urfa province located in southeastern Turkey. Herein, the epidemiological status of CL, caused by L. tropica, in Turkey was examined using multilocus microsatellite typing (MLMT) of strains obtained from Turkish and Syrian patients. A total of 38 cryopreserved strains and 20 Giemsa-stained smears were included in the present study. MLMT was performed using 12 highly specific microsatellite markers. Delta K (ΔK) calculation and Bayesian statistics were used to determine the population structure. Three main populations (POP A, B and C) were identified and further examination revealed the presence of three subpopulations for POP B and C. Combined analysis was performed using the data of previously typed L. tropica strains and Mediterranean and Şanl{\i}urfa populations were identified. This finding suggests that the epidemiological status of L. tropica is more complicated than expected when compared to previous studies. A new population, comprised of Syrian L. tropica samples, was reported for the first time in Turkey, and the data presented here will provide new epidemiological information for further studies.}, language = {en} } @article{PfeilFrohmeSchulze2018, author = {Pfeil, Juliane and Frohme, Marcus and Schulze, Katja}, title = {Mobile microscopy for the examination of blood samples}, series = {EMBnet.journal}, volume = {23}, journal = {EMBnet.journal}, issn = {2226-6089}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-10509}, pages = {e904}, year = {2018}, abstract = {The analysis of blood is one of the best possibilities to diagnose and control diseases and deficiency symptoms. Common blood tests that are performed in medical laboratories are time-consuming and work-intensive. In under-developed areas, there is often also a lack of specialised staff and facilities. The development of a mobile microscopic system that contains an automated image analysis and that can be used via a smartphone, could represent a valuable help to improve the diagnostic care, especially in those areas. it aims to enable a very fast, cheap, location- and knowledge-independent application for many use cases.}, language = {en} } @article{GerhardGimpelTascheetal.2018, author = {Gerhard, Christoph and Gimpel, Thomas and Tasche, Daniel and Koch, Jennifer and Br{\"u}ckner, Stephan and Flachenecker, G{\"u}nter and Wieneke, Stephan and Schade, Wolfgang and Vi{\"o}l, Wolfgang}, title = {Atmospheric pressure plasma-assisted femtosecond laser engraving of aluminium}, series = {Journal of Physics D: Applied Physics}, volume = {51}, journal = {Journal of Physics D: Applied Physics}, issn = {1361-6463}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-10521}, pages = {1 -- 7}, year = {2018}, abstract = {In this contribution, we report on the impact of direct dielectric barrier discharge argon plasma at atmospheric pressure on femtosecond laser engraving of aluminium. It is shown that the assisting plasma strongly affects the surface geometry and formation of spikes of both laser-engraved single lines and patterns of adjacent lines with an appropriate overlap. Further, it was observed that the overall ablation depth is significantly increased in case of large-scale patterning whereas no notable differences in ablation depth are found for single lines. Several possible mechanisms and underlying effects of this behaviour are suggested. The increase in ablation depth is supposed to be due to a plasma-induced removal of debris particles from the cutting point via charging and oxidation as supported by EDX analysis of the re-solidified debris. Furthermore, the impact of a higher degree of surface wrinkling as well as direct interactions of plasma species with the aluminium surface on the ablation process are discussed.}, language = {en} } @incollection{BorndoerferKarbsteinLiebchenetal.2018, author = {Bornd{\"o}rfer, Ralf and Karbstein, Marika and Liebchen, Christian and Lindner, Niels}, title = {A Simple Way to Compute the Number of Vehicles That Are Required to Operate a Periodic Timetable}, series = {18th Workshop on Algorithmic Approaches for Transportation Modelling, Optimization, and Systems (ATMOS 2018)}, booktitle = {18th Workshop on Algorithmic Approaches for Transportation Modelling, Optimization, and Systems (ATMOS 2018)}, editor = {Bornd{\"o}rfer, Ralf and Storandt, Sabine}, publisher = {Schloss Dagstuhl - Leibniz-Zentrum f{\"u}r Informatik GmbH}, address = {Wadern}, isbn = {978-3-95977-096-5}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-10549}, publisher = {Technische Hochschule Wildau}, pages = {16:1 -- 16:15}, year = {2018}, abstract = {We consider the following planning problem in public transportation: Given a periodic timetable, how many vehicles are required to operate it? In [Julius Paetzold et al., 2017], for this sequential approach, it is proposed to first expand the periodic timetable over time, and then answer the above question by solving a flow-based aperiodic optimization problem. In this contribution we propose to keep the compact periodic representation of the timetable and simply solve a particular perfect matching problem. For practical networks, it is very much likely that the matching problem decomposes into several connected components. Our key observation is that there is no need to change any turnaround decision for the vehicles of a line during the day, as long as the timetable stays exactly the same.}, language = {en} } @article{GerhardStappenbeck2018, author = {Gerhard, Christoph and Stappenbeck, Marco}, title = {Impact of the Polishing Suspension Concentration on Laser Damage of Classically Manufactured and Plasma Post-Processed Zinc Crown Glass Surfaces}, series = {Applied Sciences}, volume = {8}, journal = {Applied Sciences}, number = {9}, publisher = {MDPI}, issn = {2076-3417}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-10556}, pages = {1 -- 15}, year = {2018}, abstract = {The laser-induced damage threshold of optics is an issue of essential importance in high-power laser applications. However, the complex and partially interacting mechanisms as well as the underlying reasons for laser damage of glass surfaces are not yet fully understood. The aim of the present work is to contribute to a better understanding of such damage mechanisms by providing original results on the impact of classical glass surface machining on the laser-induced damage threshold. For this purpose, glass samples were prepared with well-defined process conditions in terms of the used lapping and polishing agents and suspensions. Further, the samples were post-processed by atmospheric pressure plasma for precision cleaning. The laser-induced damage threshold and surface contamination by residues from the manufacturing process were determined before and after plasma post-processing. It is shown that the polishing suspension concentration has a certain impact on the laser-induced damage threshold and surface contamination by residues from used working materials. The highest damage threshold of 15.2 J/cm² is found for the lowest surface contamination by carbon which occurs in the case of the highest polishing suspension concentration. After plasma treatment for merely 60 s, this value was increased to 20.3 J/cm² due to the removal of surface-adherent carbon. The results thus imply that the laser-induced damage threshold can notably be increased by first choosing appropriate process parameters during classical manufacturing and second plasma post-processing for surface finishing.}, language = {en} } @incollection{Steglich2018, author = {Steglich, Patrick}, title = {Silicon-on-Insulator Slot Waveguides: Theory and Applications in Electro-Optics and Optical Sensing}, series = {Emerging Waveguide Technology}, booktitle = {Emerging Waveguide Technology}, editor = {You, Kok Yeow}, publisher = {IntechOpen}, isbn = {978-1-78923-493-0}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-10563}, publisher = {Technische Hochschule Wildau}, pages = {187 -- 210}, year = {2018}, abstract = {This chapter deals with the basic concept of silicon-on-insulator (SOI) slot waveguides,including slot waveguide theory, fabrication steps, and applications. First, in the theorysection, a modal field expression and the characteristic equation is derived, which is alsovalid for higher-order modes. SOI slot waveguide structures are simulated and character-istic values like the effective refractive indices and the field confinement factors are deter-mined. The fabrication section describes typical SOI fabrication steps and the limits ofcurrent fabrication techniques. Additionally, developments regarding loss reduction inSOI slot waveguides are given from the fabrication point of view. This is followed by thetheory and practice of slot waveguide based electro-optical modulators. Here, the SOI slotwaveguide is embedded in an organic nonlinear optical material in order to achieverecord-low voltage-length products. In the field of optical sensors, it is shown that slotwaveguides enable remarkable waveguide sensitivity for both refractive index sensingand surface sensing.}, language = {en} } @article{GrebinykGrebinykPrylutskaetal.2018, author = {Grebinyk, Anna and Grebinyk, Sergii and Prylutska, Svitlana and Ritter, Uwe and Matyshevska, Olga and Dandekar, Thomas and Frohme, Marcus}, title = {C60 fullerene accumulation in human leukemic cells and perspectives of LED-mediated photodynamic therapy}, series = {Free Radical Biology and Medicine}, volume = {124}, journal = {Free Radical Biology and Medicine}, issn = {1873-4596}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-10588}, pages = {319 -- 327}, year = {2018}, abstract = {Recent progress in nanobiotechnology has attracted interest to a biomedical application of the carbon nanostructure C60 fullerene since it possesses a unique structure and versatile biological activity. C60 fullerene potential application in the frame of cancer photodynamic therapy (PDT) relies on rapid development of new light sources as well as on better understanding of the fullerene interaction with cells. The aim of this study was to analyze C60 fullerene effects on human leukemic cells (CCRF-CEM) in combination with high power single chip light-emitting diodes (LEDs) light irradiation of different wavelengths: ultraviolet (UV, 365 nm), violet (405 nm), green (515 nm) and red (632 nm). The time-dependent accumulation of fullerene C60 in CCRF-CEM cells up to 250 ng/106 cells at 24 h with predominant localization within mitochondria was demonstrated with immunocytochemical staining and liquid chromatography mass spectrometry. In a cell viability assay we studied photoexcitation of the accumulated C60 nanostructures with ultraviolet or violet LEDs and could prove that significant phototoxic effects did arise. A less pronounced C60 fullerene phototoxic effect was observed after irradiation with green, and no effect was detected with red light. A C60 fullerene photoactivation with violet light induced substantial ROS generation and apoptotic cell death, confirmed by caspase3/7 activation and plasma membrane phosphatidylserine externalization. Our work proved C60 fullerene ability to induce apoptosis of leukemic cells after photoexcitation with high power single chip 405 nm LED as a light source. This underlined the potential for application of C60 nanostructure as a photosensitizer for anticancer therapy.}, language = {en} } @article{MeierGrawBeyerleinetal.2017, author = {Meier, Richard and Graw, Stefan and Beyerlein, Peter and Koestler, Devin and Molina, Julian R. and Chien, Jeremy}, title = {digit—a tool for detection and identification of genomic interchromosomal translocations}, series = {Nucleic Acids Research}, volume = {45}, journal = {Nucleic Acids Research}, number = {9}, issn = {1362-4962}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-9697}, pages = {e72}, year = {2017}, abstract = {Structural variations (SVs) in genomic DNA can have profound effects on the evolution of living organisms, on phenotypic variations and on disease processes. A critical step in discovering the full extent of structural variations is the development of tools to characterize these variations accurately in next generation sequencing data. Toward this goal, we developed a software pipeline named digit that implements a novel measure of mapping ambiguity to discover interchromosomal SVs from mate-pair and pair-end sequencing data. The workflow robustly handles the high numbers of artifacts present in mate-pair sequencing and reduces the false positive rate while maintaining sensitivity. In the simulated data set, our workflow recovered 96\% of simulated SVs. It generates a self-updating library of common translocations and allows for the investigation of patient- or group-specific events, making it suitable for discovering and cataloging chromosomal translocations associated with specific groups, traits, diseases or population structures.}, language = {en} } @article{KinuthiaFrohmeBroedeletal.2017, author = {Kinuthia, Chuaga and Frohme, Marcus and Br{\"o}del, Oliver and Mugendi, Beatrice}, title = {LCMS Analysis of Biochemical Composition in Different Kenyan Coffee Classifications}, series = {Food Science and Quality Management}, volume = {69}, journal = {Food Science and Quality Management}, issn = {2225-0557}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-10185}, pages = {44 -- 52}, year = {2017}, abstract = {Kenyan coffee is classified by defects after grading by the 'Devonshire method.' The method involves classification of the coffee beans into different classes based on the raw and roasted coffees and cup quality, with class one being the best and ten the poorest. In this study, the relationship between classification of the coffee and the content of sucrose, trigonelline, caffeine and chlorogenic acids was determined by simultaneous LC-MS analysis. By using the sensory variables the class 3 coffee portrayed the best quality, followed by class 4 and 5 which were placed further distinctively from the other classes (6, 7, 8 and 9). The class 3 coffee had a high percent of non-defective beans with 94.31\% and class 9 had a high defect count at 79.53\% hence the defective beans increased with decrease in coffee class. The caffeine concentration in green coffee for class 3 coffee was significantly different from the rest of the coffees at 1.23 ± 0.00g/100g. A higher content of trigonelline levels was observed as the quality of the green coffee decreased in classes 6, 7 and 8. The highest level of sucrose in green coffee beans was observed in class 3 coffee and the lowest in the class 9. Lower content of chlorogenic acids were observed among the high quality coffees i.e. class 3, 4 and 5 with class 3 having the lowest while a higher content was observed among the lower quality coffees i.e. classes 6, 7 and 9 with class 6 having a higher content was it significantly different in class 6 compared to 7 and 9?. Quantities of different chemical components among the classes are clear indicators that the classification method used on the Kenyan coffees brings out the differences in coffee quality based on the analysis of the green and the roasted coffees.}, language = {en} } @inproceedings{JacobKubica2017, author = {Jacob, Thomas and Kubica, Stefan}, title = {Einsatz von Stream-Machine-Learning auf Fahrzeugdaten}, series = {2. Automobil Symposium Wildau: Tagungsband Technische Hochschule Wildau 2017}, booktitle = {2. Automobil Symposium Wildau: Tagungsband Technische Hochschule Wildau 2017}, editor = {Kubica, Stefan and Ringshausen, Hagen and Reiff-Stephan, J{\"o}rg and Schlingelhof, Marius}, doi = {10.15771/ASW_2017_6}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-9039}, pages = {39 -- 46}, year = {2017}, abstract = {Daten liegen in modernen Fahrzeugen in einer großen Menge vor. Die Daten, welche die Sensoren des Fahrzeuges erzeugen, werden {\"u}ber Bus-Systeme zentral zur Verf{\"u}gung gestellt und f{\"u}r die jeweiligen Anwendungen von den Steuerger{\"a}ten ausgewertet. Nach diesem Einsatz werden die Sensordaten verworfen. Eine Herausforderung an die Verwendung jener Daten sind die Historisierung und systematische Auswertung dieser. Daf{\"u}r werden Data-Mining-Methoden angewandt, welche die internen sowie die externen Daten (Car2X-Kommunikation) in Echtzeit auswerten und mit dem digitalem Ged{\"a}chtnis abgleichen. Ziel dessen ist die Erkennung von Mustern, zur Identifikation von Situationen (z.B. Verkehrsunfall) und Fahrzust{\"a}nden (z.B. Autobahnfahrt). Als Ergebnisse sollen der Komfort der Insassen und die Sicherheit des Straßenverkehrs verbessert werden. Potentiell bedrohliche Situationen sollen dabei vor dem Eintreffen erkannt werden, um Fahrer und Fahrzeug entsprechend zu konditionieren. Das Vorhaben zielt konkret auf ein Echtzeit-Data-Mining von Fahrzeugdaten ab. Dabei wird Stream-Machine-Learning als m{\"o}glicher L{\"o}sungsansatz verwendet, da große Datenmengen vorhanden sind und diese in Echtzeit ausgewertet werden m{\"u}ssen, um potentiell bedrohliche Situationen fr{\"u}hzeitig zu erkennen. Der klassische Batch-Learning-Ansatz ist dazu nicht geeignet, da jener alle Daten mit einmal verarbeiten will. Stream-Machine-Learning kombiniert das Konzept von Datenstr{\"o}men mit dem Online-Lernen. Dadurch verwendet der Ansatz nur die im Stream empfangenden Daten und zudem lernt er w{\"a}hrend des Betriebs weiter. Nach jeder verarbeiteten Instanz ist es dem Algorithmus m{\"o}glich ein Modell auszugeben bzw. das vorhandene Modell wird weiter trainiert. Ein selbstst{\"a}ndiges Lernen wird erm{\"o}glicht. F{\"u}r die Umsetzung ist eine Toolchain erstellt worden, die das Vorhaben mit vom Fahrzeug erzeugten und {\"u}ber die OBD2-Schnittstelle bereitgestellten Datens{\"a}tzen simuliert darstellt. Dabei ist besonderes Augenmerk auf die Komptabilit{\"a}t zu in Fahrzeugen genutzten Betriebssysteme (Linux, Autosar [WaPa12]) gelegt, damit eine Migration gew{\"a}hrleistet wird.}, language = {de} } @article{MaierClausiusRichteretal.2021, author = {Maier, Petra and Clausius, Benjamin and Richter, Asta and Bittner, Benjamin and Hort, Norbert and Menze, Roman}, title = {Crack Propagation in As-Extruded and Heat-Treated Mg-Dy-Nd-Zn-Zr Alloy Explained by the Effect of LPSO Structures and Their Micro- and Nanohardness}, series = {Materials}, volume = {14}, journal = {Materials}, number = {13}, publisher = {MDPI}, issn = {1996-1944}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-14194}, year = {2021}, abstract = {The investigation of the crack propagation in as-extruded and heat-treated Mg-Dy-Nd-Zn-Zr alloy with a focus on the interaction of long-period stacking-ordered (LPSO) structures is the aim of this study. Solution heat treatment on a hot extruded Mg-Dy-Nd-Zn-Zr (RESOLOY®) was done to change the initial fine-grained microstructure, consisting of grain boundary blocky LPSO and lamellar LPSO structures within the matrix, into coarser grains of less lamellar and blocky LPSO phases. C-ring compression tests in Ringer solution were used to cause a fracture. Crack initiation and propagation is influenced by twin boundaries and LPSO lamellae. The blocky LPSO phases also clearly hinder crack growth, by increasing the energy to pass either through the phase or along its interface. The microstructural features were characterized by micro- and nanohardness as well as the amount and location of LPSO phases in dependence on the heat treatment condition. By applying nanoindentation, blocky LPSO phases show a higher hardness than the grains with or without lamellar LPSO phases and their hardness decreases with heat treatment time. On the other hand, the matrix increases in hardness by solid solution strengthening. The microstructure consisting of a good balance of grain size, matrix and blocky LPSO phases and twins shows the highest fracture energy.}, language = {en} } @article{GrebinykPrylutskaGrebinyketal.2021, author = {Grebinyk, Anna and Prylutska, Svitlana and Grebinyk, Sergii and Evstigneev, Maxim and Krysiuk, Iryna and Skaterna, Tetiana and Horak, Iryna and Sun, Yanfang and Drobot, Liudmyla and Matyshevska, Olga and Prylutskyy, Yuriy and Ritter, Uwe and Frohme, Marcus}, title = {Antitumor efficiency of the natural alkaloid berberine complexed with C60 fullerene in Lewis lung carcinoma in vitro and in vivo}, series = {Cancer Nanotechnology}, volume = {12}, journal = {Cancer Nanotechnology}, publisher = {BioMed Central}, issn = {1868-6966}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-14749}, pages = {24}, year = {2021}, abstract = {Background Berberine (Ber) is a herbal alkaloid with pharmacological activity in general and a high anticancer potency in particular. However, due to its low bioavailability, the difficulty in reaching a target and choosing the right dose, there is a need to improve approaches of Ber use in anticancer therapy. In this study, Ber, noncovalently bound to a carbon nanostructure C60 fullerene (C60) at various molar ratios of the components, was explored against Lewis lung carcinoma (LLC). Methods C60-Ber noncovalent nanocomplexes were synthesized in 1:2, 1:1 and 2:1 molar ratios. Ber release from the nanocomplexes was studied after prolonged incubation at different pH with the liquid chromatography-mass spectrometry analysis of free Ber content. Biological effects of the free and C60-complaxated Ber were studied in vitro towards LLC cells with phase-contrast and fluorescence microscopy, flow cytometry, MTT reduction, caspase activity and wound closure assays. The treatment with C60-Ber nanocomplex was evaluated in vivo with the LLC-tumored C57Bl mice. The mice body weight, tumor size, tumor weight and tumor weight index were assessed for four groups, treated with saline, 15 mg C60/kg, 7.5 mg Ber/kg or 2:1 C60-Ber nanocomplex (15 mg C60/kg, 7.5 mg Ber/kg). Results Ber release from C60-Ber nanocomplexes was promoted with medium acidification. LLC cells treatment with C60-Ber nanocomplexes was followed by enhanced Ber intracellular uptake as compared to free Ber. The cytotoxicity of the studied agents followed the order: free Ber < 1:2 < 1:1 < 2:1 C60-Ber nanocomplex. The potency of cytotoxic effect of 2:1 C60-Ber nanocomplex was confirmed by 21.3-fold decrease of IC50 value (0.8 ± 0.3 µM) compared to IC50 for free Ber (17 ± 2 µM). C60-Ber nanocomplexes induced caspase 3/7 activation and suppressed the migration activity of LLC cells. The therapeutic potency of 2:1 C60-Ber nanocomplex was confirmed in a mouse model of LLC. The tumor growth in the group treated with 2:1 C60-Ber nanocomplex is suppressed by approximately 50\% at the end of experiment, while in the tumor-bearing group treated with free Ber no therapeutic effect was detected. Conclusions This study indicates that complexation of natural alkaloid Ber with C60 may be a novel therapeutic strategy against lung carcinoma.}, language = {en} } @article{GoldenbergKoehlerDreyer2021, author = {Goldenberg, Leonid and K{\"o}hler, Mathias and Dreyer, Christian}, title = {SiO2 Nanoparticles-Acrylate Formulations for Core and Cladding in Planar Optical Waveguides}, series = {Nanomaterials}, volume = {11}, journal = {Nanomaterials}, number = {5}, publisher = {MDPI}, issn = {2079-4991}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-14057}, year = {2021}, abstract = {A combination of acrylate formulations and SiO2 nanoparticles is investigated with the aim to improve the optical properties of low-refractive index polymers that are used for the fabrication of planar optical waveguides. A decrease in refractive index and also in the thermo-optic coefficient of nanocomposite materials is clearly demonstrated, while some formulations exhibit an increase in the glass transition temperature. The possibility of using these nanocomposite materials to fabricate waveguiding layers with low optical propagation losses at telecommunication wavelengths around 1550 nm is also shown. The nanomaterials can be applied in optical microchips on polymer platforms.}, language = {en} } @article{Ruediger2020, author = {R{\"u}diger, Jens}, title = {Enhancements of the numerical simulation algorithm for natural gas networks based on node potential analysis}, series = {IFAC-PapersOnLine}, volume = {53}, journal = {IFAC-PapersOnLine}, number = {2}, issn = {2405-8963}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-14129}, pages = {13119 -- 13124}, year = {2020}, abstract = {A reliable energy supply for the economy of every country is a matter of national importance. Powerful simulation tools for natural gas networks are essential for operators of gas networks. In this paper, enhancement algorithms of previous developed node potential analysis algorithm are presented. These enhancement algorithms are used for a reasonable setting of initial values in the numerical gas net simulation algorithm. The setting of the initial values has a significant influence on the convergence behavior of the numerical simulation. The presented enhancement algorithms are explained and simulation results are evaluated.}, language = {en} } @phdthesis{Grebinyk2021, author = {Grebinyk, Anna}, title = {Synergistic Chemo- and Photodynamic Treatment of Cancer Cells with C60 Fullerene Nanocomplexes}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-14137}, school = {Technische Hochschule Wildau}, year = {2021}, abstract = {Recent progress in nanotechnology has attracted interest to a biomedical application of the carbon nanoparticle C60 fullerene (C60) due to its unique structure and versatile biological activity. In the current study the dual functionality of C60 as a photosensitizer and a drug nanocarrier was exploited to improve the efficiency of chemotherapeutic drugs towards human leukemic cells. Pristine C60 demonstrated time-dependent accumulation with predominant mitochondrial localization in leukemic cells. C60's effects on leukemic cells irradiated with high power single chip LEDs of different wavelengths were assessed to find out the most effective photoexcitation conditions. A C60-based noncovalent nanosized system as a carrier for an optimized drug delivery to the cells was evaluated in accordance to its physicochemical properties and toxic effects. Finally, nanomolar amounts of C60-drug nanocomplexes in 1:1 and 2:1 molar ratios were explored to improve the efficiency of cell treatment, complementing it with photodynamic approach. A proposed treatment strategy was developed for C60 nanocomplexes with the common chemotherapeutic drug Doxorubicin, whose intracellular accumulation and localization, cytotoxicity and mechanism of action were investigated. The developed strategy was revealed to be transferable to an alternative potent anticancer drug - the herbal alkaloid Berberine. Hereafter, a strong synergy of treatments arising from the combination of C60-mediated drug delivery and C60 photoexcitation was revealed. Presented data indicate that a combination of chemo- and photodynamic treatments with C60-drug nanoformulations could provide a promising synergetic approach for cancer treatment.}, subject = {cancer}, language = {en} } @article{GrytsenkoKsianzouKolomzarovetal.2021, author = {Grytsenko, Kostyantyn and Ksianzou, Viachaslau and Kolomzarov, Yurii and Lytvyn, Peter and Dietzel, Birgit and Schrader, Sigurd}, title = {Fluoropolymer Film Formation by Electron Activated Vacuum Deposition}, series = {Surfaces}, volume = {4}, journal = {Surfaces}, number = {1}, publisher = {MDPI}, issn = {2571-9637}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-13786}, pages = {66 -- 80}, year = {2021}, abstract = {Polytetrafluoroethylene (PTFE), polyhexafluoropropylene (PHFP) and polychlorotrifluoroethylene (PCTFE) were heated to their decomposition temperature in a high vacuum. The emitted fragments passed an electron cloud, condensed on a substrate and formed fluoropolymer film. Growth rate of PTFE and PHFP films increased up to a factor five in the presence of the electron cloud. Mass spectrometry revealed changes in the mass spectra of fragments generated by thermal decomposition only and formed under electron activation. The observed changes were different for each fluoropolymer. Infrared spectroscopy (IRS) showed that the structure of the films was close to the structure of the bulk polymers. Atomic force microscopy (AFM) has revealed different morphologies of PTFE, PHFP and PCTFE films, suggesting a Volmer-Weber growth mechanism for PTFE and PHFP but a Frank-van der Merwe one for PCTFE. All films were smooth at nanoscale and transparent from ultraviolet to near-infrared region. Additional radio frequency (RF) plasma ignited in the emitted fragments at a low pressure increased mechanical characteristics of the films without losing their optical transparency and smoothness.}, language = {en} } @article{Lisdat2020, author = {Lisdat, Fred}, title = {Coupling biology to electrochemistry—future trends and needs}, series = {Journal of Solid State Electrochemistry}, volume = {24}, journal = {Journal of Solid State Electrochemistry}, publisher = {Springer Nature}, issn = {1433-0768}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-13639}, pages = {2125 -- 2127}, year = {2020}, abstract = {The coupling of biological entities with electrodes has already quite some history and has reached a status which is not only based on phenomenological descriptions. Nowadays, we are able to effectively couple redox centres within protein molecules to electrochemical transducers. This allows the transduction of a biochemical reaction into an electrode signal with applications mainly in sensing and bioenergetics [1,2,3,4,5,6,7,8]. However, in most cases, this coupling is not direct, and shuttle molecules or side products of the reaction are used. But also for the direct coupling, significant progress has been made, and several enzymes and redox proteins can be addressed directly by electrodes [8,9,10,11,12,13]. The understanding of the functioning of developed systems is, however, in its infancy. Charge and electrostatic interactions have been mostly studied, and for small dipole molecules such as cytochrome c, the situation can be well described [14]. There is a lack of understanding for more complex enzyme molecules which brings a lot of trial and error into research.}, language = {en} } @article{GoebelTalkeAhnertetal.2019, author = {G{\"o}bel, Gero and Talke, Anja and Ahnert, Uwe and Lisdat, Fred}, title = {Electrochemical Activity Determination of Catechol-O-methyl Transferase by Selective Dopamine Detection}, series = {ChemElectroChem}, volume = {6}, journal = {ChemElectroChem}, number = {17}, publisher = {Wiley}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-13900}, pages = {4533 -- 4540}, year = {2019}, abstract = {For the treatment of Parkinson's disease, as one of the most frequent diseases of the central nervous system, several key enzymes for dopamine metabolism [e. g. catechol-O-methyl transferase (COMT)] are drug targets. For an efficient and long-lasting treatment, the activity of this enzyme should be monitored. In this study, an electrochemical approach using differential pulse voltammetry (DPV) is introduced for the activity determination. The applied electrode material, fluorine-doped tin oxide (FTO), is characterized by a clear discrimination between substrate and product of COMT, a high stability of the dopamine signal during consecutive measurements, and a linear dependency on the dopamine concentration in the range of the maximum reaction rate of COMT. Despite these advantageous results, dopamine detection in the complete activity assay is influenced by each of the added essential assay components, even though none of the added components reveal a current signal at the FTO electrode itself. After adjusting the potential range and the assay composition, these effects can be circumvented. By following the dopamine concentrations during COMT action, it can be shown that the activity of COMT can be detected by using differential pulse voltammetry (DPV) at an FTO electrode and, by analyzing different COMT amounts, quantification can be demonstrated.}, language = {en} } @article{KeNieLiebchenetal.2020, author = {Ke, Yu and Nie, Lei and Liebchen, Christian and Yuan, Wuyang and Wu, Xin}, title = {Improving Synchronization in an Air and High-Speed Rail Integration Service via Adjusting a Rail Timetable: A Real-World Case Study in China}, series = {Journal of Advanced Transportation}, volume = {2020}, journal = {Journal of Advanced Transportation}, publisher = {Hindawi}, issn = {2042-3195}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-13105}, year = {2020}, abstract = {Air and high-speed rail (AH) integration services are gaining ground with the development of the high-speed railway and airline industries. A well-designed feeder train timetable with good synchronization is of great significance in an AH integration service, because it can improve the connectivity at transfer nodes and offer more opportunities for intermodal passengers to travel. In this study, we propose a multi-objective model of a feeder railway timetable problem in an AH integration service to improve synchronization. The aims of the optimization model are to maximize the number of synchronizations and the coverage of synchronized flights, as well as to minimize the transfer penalties of passengers. We focus on a scenario of a partial subnetwork in which one direction of a two-direction railroad line with one transfer station is considered. The model is applied to Shijiazhuang Zhengding International Airport, China. The results illustrate the effectiveness of the approach developed in the paper.}, language = {en} } @article{GerhardLetienCressentetal.2020, author = {Gerhard, Christoph and Letien, Emilie and Cressent, Thomas and Hofmann, Mandy}, title = {Inline monitoring of hydrogenous plasma-induced defect formation within fused silica via plasma emission spectroscopy}, series = {Applied Physics A: Materials Science and Processing}, volume = {126}, journal = {Applied Physics A: Materials Science and Processing}, issn = {1432-0630}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-13118}, year = {2020}, abstract = {In this paper, the indirect monitoring of plasma-induced defect formation within fused silica via plasma emission spectroscopy is presented. It is shown that low-pressure plasma treatment with hydrogen as process gas leads to a decrease in UV transmission of fused silica. This decrease can be directly attributed to oxygen vacancy-related defects and the presence of hydrogen within the silicon dioxide glass network. By the analysis of the plasma composition, it was observed that the amount of oxygen within the plasma increases with increasing treatment duration. Hence, oxygen was continuously released from glass network in the course of the plasma treatment. It was further observed that this release is strongly dependent on the applied plasma power where the lowest process efficiency occurs at the highest plasma power. It is shown that an increase in plasma power leads to a remarkable increase in light emission from the working gas, hydrogen. This observation indicates that the higher the degree of excitation and ionisation of the plasma, the lower the efficiency of plasma-induced formation of oxygen deficiency-related defects. This finding is of mentionable relevance for a better understanding of plasma-induced surface modification and coating processes.}, language = {en} } @article{PajčinVlajkovFrohmeetal.2020, author = {Pajčin, Ivana and Vlajkov, Vanja and Frohme, Marcus and Grebinyk, Sergii and Grahovac, Mila and Mojićević, Marija and Grahovac, Jovana}, title = {Pepper Bacterial Spot Control by Bacillus velezensis: Bioprocess Solution}, series = {Microorganisms}, volume = {8}, journal = {Microorganisms}, number = {10}, publisher = {MDPI}, issn = {2076-2607}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-13510}, year = {2020}, abstract = {Pepper bacterial spot is one of the most severe plant diseases in terms of infection persistence and economic losses when it comes to fresh pepper fruits used in nutrition and industrial processing. In this study, Bacillus velezensis IP22 isolated from fresh cheese was used as a biocontrol agent of pepper bacterial spot, whose main causal agent is the cosmopolitan pathogen Xanthomonas euvesicatoria. After optimization of the cultivation medium composition aimed at maximizing of the antimicrobial activity against X. euvesicatoria and validation of the optimized medium at the scale of a laboratory bioreactor, in planta tests were performed. The results have showed significant suppression of bacterial spot symptoms in pepper plants by the produced biocontrol agent, as well as reduction of disease spreading on the healthy (uninoculated) pepper leaves. Furthermore, HPLC-MS (high pressure liquid chromatography-mass spectrometry) analysis was employed to examine antimicrobial metabolites produced by B. velezensis IP22, where lipopeptides were found with similar m/z values compared to lipopeptides from fengycin and locillomycin families. The bioprocess solution developed at the laboratory scale investigated in this study represents a promising strategy for production of pepper bacterial spot biocontrol agent based on B. velezensis IP22, a food isolate with a great perspective for application in plant protection.}, language = {en} } @article{GoldenbergKoehlerKahleetal.2020, author = {Goldenberg, Leonid and K{\"o}hler, Mathias and Kahle, Olaf and Dreyer, Christian}, title = {Impact of inorganic nanoparticles on optical properties of low refractive index waveguiding polymers}, series = {Optical Materials Express}, volume = {10}, journal = {Optical Materials Express}, number = {11}, issn = {2159-3930}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-13521}, pages = {2987 -- 2997}, year = {2020}, abstract = {The objective of this work is to improve the optical properties of low refractive index polymers used for waveguide by introduction of inorganic nanoparticles. Copolymers of fluorinated monomers and glycidyl methacrylate are used. Introduction of SiO2 nanoparticles into polymer matrix is performed by direct mixing; copolymerization with SiO2 nanoparticles modified by monomer, and in situ sol-gel formation of SiO2 during photochemical cross-linking and annealing catalyzed by photoacid generator. It is demonstrated that nanoparticles are able to decrease thermo-optic coefficient. It is also possible to fabricate waveguiding layers by direct introduction of nanoparticles without compromising of optical propagation losses.}, language = {en} } @misc{KornejewDimitrovHerzog2014, author = {Kornejew, Eckhart and Dimitrov, Kiril and Herzog, Michael}, title = {New aromatic polyesterpolyols derived from PET industrial wastes}, series = {Wissenschaftliche Beitr{\"a}ge 2014}, volume = {18}, journal = {Wissenschaftliche Beitr{\"a}ge 2014}, issn = {0949-8214}, doi = {10.15771/0949-8214_2014_1_9}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-3363}, pages = {71 -- 75}, year = {2014}, abstract = {China hat den globalen Recycling-Markt letztes Jahr mit der Ank{\"u}ndigung geschockt, nicht l{\"a}nger niederwertige Qualit{\"a}ten von rezyklierbaren Abf{\"a}llen von ausl{\"a}ndischen Exporteuren zu akzeptieren - die so genannte „Aktion Gr{\"u}ner Zaun" startete zu Beginn des Jahres 2013. Die Antwort im Westen sollte ein Innovations- und Investitionsschub in Recycling-Technologie zur Entwicklung eines erfolgreichen Recycling-Marktes sein. Dies sollte hochentwickelte Behandlungstechnologien und installierte Anlagentechnik umfassen. F{\"u}r PET-Getr{\"a}nkeflaschen aus den Pfandsystemen haben wir einen Prozess des rohstofflichen Recyclings entwickelt, mit dem Ausgangsstoffe f{\"u}r verschiedene technische Anwendungen gewonnen werden k{\"o}nnen. Die gewonnenen Aromatischen Polyesterpolyole (APP) dienen hierbei als Ausgangsstoffe zur Herstellung von Polyurethanen.}, language = {en} } @misc{RoeschSchollStreweetal.2014, author = {R{\"o}sch, Olga and Scholl, Margit and Strewe, Bettina and Niemczik, Christian and Teske, Anja}, title = {Onlinekurs "Interkulturelles Lernen und Arbeiten" als ein Baustein der interkulturellen Qualifizierung - Anmerkungen zum Einsatz}, series = {Wissenschaftliche Beitr{\"a}ge 2014}, volume = {18}, journal = {Wissenschaftliche Beitr{\"a}ge 2014}, issn = {0949-8214}, doi = {10.15771/0949-8214_2014_1_15}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-3427}, pages = {117 -- 125}, year = {2014}, abstract = {Im Rahmen des Verbundprojekts „InterKomp KMU 2.0" ist im Teilprojekt „Technik und Kultur" der TH Wildau [FH] ein computergest{\"u}tztes Lehrwerk zu interkulturellen Kompetenzen f{\"u}r KMU und insbesondere f{\"u}r KKU in Brandenburg entstanden, das inhaltlich und methodisch sowohl mehreren Anforderungen an Weiterbildungsangebote im Themenfeld Interkulturalit{\"a}t entspricht als auch dem Lehr- und Lernformat Blended Learning (BL) gen{\"u}gt. Der modular aufgebaute Onlinekurs bildet thematisch die wichtigsten Schwerpunkte des Bereiches Interkulturelles Lernen ab, stellt eine bereichernde Erg{\"a}nzung f{\"u}r jede interkulturelle Bildungsmaßnahme dar und ist f{\"u}r Nutzer frei und kostenlos zug{\"a}nglich. F{\"u}r das selbstst{\"a}ndige Lernen ist der Onlinekurs eine gute M{\"o}glichkeit, eine gr{\"o}ßere Sensibilit{\"a}t f{\"u}r interkulturellen Kontexte zu entwickeln und das Grundlagenwissen auf dem Gebiet der interkulturellen Kommunikation anzueignen. Allerdings muss er als Lehrund Lernmaterial in den Gesamtzusammenhang der interkulturellen Bildung eingebettet und der Lernprozess durch diskursive Lernmethoden in den Pr{\"a}senzphasen professionell begleitet werden, um das Lernziel interkultureller Handlungskompetenz zu erreichen.}, language = {de} } @misc{LiskerHellwigWildenauer2015, author = {Lisker, Roberto and Hellwig, Udo and Wildenauer, Franz-Xaver}, title = {Entwicklung und Leistungsbestimmung einer 2,2 kW Tesla Turbine}, series = {Wissenschaftliche Beitr{\"a}ge 2015}, volume = {19}, journal = {Wissenschaftliche Beitr{\"a}ge 2015}, issn = {0949-8214}, doi = {10.15771/0949-8214_2015_1_8}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-3582}, pages = {61 -- 66}, year = {2015}, abstract = {Im Folgenden wird die Entwicklung und Evaluation eines 2,2 kW Tesla Turbinen Prototyps beschrieben. Ausgehend von der konstruktiven Verbesserung der Ein- und Auslassstr{\"o}mung - mit dem Ziel der Steigerung des isentropen Wirkungsgrades - wurde ein Turbinenprototyp gefertigt und auf einem Turbinenversuchsstand erprobt. Hierbei wurde untersucht, ob eine Wirkungsgradsteigerung mit einem Profileinsatz m{\"o}glich ist. Die gewonnenen Ergebnisse lagen im Erwartungsbereich und zeigten, dass der Profileinsatz zu einer Wirkungsgradsteigerung bei beitr{\"a}gt.}, language = {de} } @inproceedings{JacobKubica2016, author = {Jacob, Thomas and Kubica, Stefan}, title = {Data-Mining-Methoden zur fr{\"u}hzeitigen Erkennung bedrohlicher Situationen im Fahrzeug}, series = {1. Automobil Symposium Wildau: Tagungsband}, booktitle = {1. Automobil Symposium Wildau: Tagungsband}, editor = {Kubica, Stefan and Ringshausen, Hagen and Reiff-Stephan, J{\"o}rg and Schlingelhof, Marius}, doi = {10.15771/ASW_2016_9}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-5576}, pages = {59 -- 63}, year = {2016}, abstract = {Das autonome Fahren ist eines der großen Themen im Automobilbereich der Gegenwart. Umsatzstarke Soft­ware-Unternehmen gehen Kooperationen mit Unter­nehmen der Automobilbranche ein, um das automati­sierte Fahren schnellstm{\"o}glich voranzutreiben (Fuest 2015). Gleichzeitig forschen diverse Universit{\"a}ten an dem Thema und zeigen bereits weitgehende Fortschrit­te. Exemplarisch ist die Universit{\"a}t Ulm zu nennen, die bereits Testfahrten im urbanen Gebiet erfolgreich absol­viert hat (Dietmayer 2014). Auch die Politik f{\"o}rdert den Forschungsschwerpunkt zunehmend. Als Beispiel ist das F{\"o}rderprogramm »Elektroniksysteme f{\"u}r das vollauto­matisierte Fahren (ELEVATE)« zu nennen, welches vom Bundesministerium f{\"u}r Bildung und Forschung angebo­ten wird (Bundesministerium f{\"u}r Bildung und Forschung 2015). Diese intensive Forschung, die gleichzeitig von der Wirtschaft, der Wissenschaft und der Politik vorange­trieben wird, zeigt wie viel Potential das Thema besitzt. Auch dadurch stellen sich neue Herausforderungen an die Sensorik innerhalb der Fahrzeuge. Aktuell wird der Großteil der Sensordaten einmalig f{\"u}r den jeweiligen Zweck genutzt und anschließend verworfen. An diesen Punkt setzen das Vorhaben und der damit ver­bundene Einsatz von Data-Mining-Methoden an. Ziel ist die systematische Auswertung von Daten im Fahrzeug und von außerhalb (Car2X) in Echtzeit, um aktuelle Fahrsituationen mit einem digitalen Ged{\"a}chtnis abzu­gleichen und somit einen kurzen Blick in die Zukunft abzuleiten. Hierbei werden Situationen durch Muster erkannt und Fahrzeug bzw. Fahrer konditioniert, um die Situation positiv zu beeinflussen. Das Vorhaben ist nicht ausschließlich auf das autonome Fahren ausgerichtet, sondern auch als Hilfe f{\"u}r fahrerge­lenkte Fahrzeuge konzipiert.}, language = {de} } @article{SternPaulyZydeketal.2016, author = {Stern, Daniel and Pauly, Diana and Zydek, Martin and Miller, Lilija and Piesker, Janett and Laue, Michael and Lisdat, Fred and Dorner, Martin B. and Dorner, Brigitte G. and Nitsche, Andreas}, title = {Development of a Genus-Specific Antigen Capture ELISA for Orthopoxviruses - Target Selection and Optimized Screening}, series = {PLoS ONE}, volume = {11}, journal = {PLoS ONE}, number = {3}, issn = {1932-6203}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-5830}, pages = {22}, year = {2016}, abstract = {Orthopoxvirus species like cowpox, vaccinia and monkeypox virus cause zoonotic infections in humans worldwide. Infections often occur in rural areas lacking proper diagnostic infrastructure as exemplified by monkeypox, which is endemic in Western and Central Africa. While PCR detection requires demanding equipment and is restricted to genome detection, the evidence of virus particles can complement or replace PCR. Therefore, an easily distributable and manageable antigen capture enzyme-linked immunosorbent assay (ELISA) for the detection of orthopoxviruses was developed to facilitate particle detection. By comparing the virus particle binding properties of polyclonal antibodies developed against surface-exposed attachment or fusion proteins, the surface protein A27 was found to be a well-bound, highly immunogenic and exposed target for antibodies aiming at virus particle detection. Subsequently, eight monoclonal anti-A27 antibodies were generated and characterized by peptide epitope mapping and surface plasmon resonance measurements. All antibodies were found to bind with high affinity to two epitopes at the heparin binding site of A27, toward either the N- or C-terminal of the crucial KKEP-segment of A27. Two antibodies recognizing different epitopes were implemented in an antigen capture ELISA. Validation showed robust detection of virus particles from 11 different orthopoxvirus isolates pathogenic to humans, with the exception of MVA, which is apathogenic to humans. Most orthopoxviruses could be detected reliably for viral loads above 1 × 103 PFU/mL. To our knowledge, this is the first solely monoclonal and therefore reproducible antibody-based antigen capture ELISA able to detect all human pathogenic orthopoxviruses including monkeypox virus, except variola virus which was not included. Therefore, the newly developed antibody-based assay represents important progress towards feasible particle detection of this important genus of viruses.}, language = {en} } @article{KoberMeyerAlertGrienitzetal.2015, author = {Kober, Liane and Meyer-Alert, Henriette and Grienitz, Desir{\´e}e and Hollert, Henner and Frohme, Marcus}, title = {Intact cell mass spectrometry as a rapid and specific tool for the differentiation of toxic effects in cell-based ecotoxicological test systems}, series = {Analytical and Bioanalytical Chemistry}, volume = {407}, journal = {Analytical and Bioanalytical Chemistry}, number = {25}, issn = {1618-2650}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-5900}, pages = {7721 -- 7731}, year = {2015}, abstract = {In the last few decades, MALDI-TOF MS has become a useful technique not only in proteomics, but also as a fast and specific tool for whole cell analysis through intact cell mass spectrometry (IC-MS). The present study evaluated IC-MS as a novel tool for the detection of distinct patterns that can be observed after exposure to a certain toxin or concentration by utilizing the eukaryotic fish cell line RTL-W1. Two different viability assays were performed to define the range for IC-MS investigations, each of which employing copper sulfate, acridine, and β-naphthoflavone (BNF) as model compounds for several classes of environmental toxins. The IC-MS of RTL-W1 cells revealed not only specific spectral patterns for the various toxins, but also that the concentration used had an effect on RTL-W1 profiles. After the exposure with copper sulfate and acridine, the spectra of RTL-W1 showed a significant increase of certain peaks in the higher mass range (m/z >7000), which is probably attributed to the apoptosis of RTL-W1. On the contrary, exposure to BNF showed a distinct change of ion abundances only in the lower mass range (m/z <7000). Furthermore, a set of mass peaks could be identified as a specific biomarker for a single toxin treatment, so IC-MS demonstrates a new method for the distinction of toxic effects in fish cells. Due to fast sample preparation and high throughput, IC-MS offers great potential for ecotoxicological studies to investigate cellular effects of different substances and complex environmental samples.}, language = {en} } @article{SchulzeLangEnkeetal.2015, author = {Schulze, Katja and Lang, Imke and Enke, Heike and Grohme, Diana and Frohme, Marcus}, title = {The use of fluorescence microscopy and image analysis for rapid detection of non-producing revertant cells of Synechocystis sp. PCC6803 and Synechococcus sp. PCC7002}, series = {BMC Research Notes}, volume = {8}, journal = {BMC Research Notes}, number = {160}, issn = {1756-0500}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-5911}, pages = {11}, year = {2015}, abstract = {Ethanol production via genetically engineered cyanobacteria is a promising solution for the production of biofuels. Through the introduction of a pyruvate decarboxylase and alcohol dehydrogenase direct ethanol production becomes possible within the cells. However, during cultivation genetic instability can lead to mutations and thus loss of ethanol production. Cells then revert back to the wild type phenotype. A method for a rapid and simple detection of these non-producing revertant cells in an ethanol producing cell population is an important quality control measure in order to predict genetic stability and the longevity of a producing culture. Several comparable cultivation experiments revealed a difference in the pigmentation for non-producing and producing cells: the accessory pigment phycocyanin (PC) is reduced in case of the ethanol producer, resulting in a yellowish appearance of the culture. Microarray and western blot studies of Synechocystis sp. PCC6803 and Synechococcus sp. PCC7002 confirmed this PC reduction on the level of RNA and protein.}, language = {en} } @article{BilousMalkoFrohmeetal.2024, author = {Bilous, Nataliya and Malko, Vladyslav and Frohme, Marcus and Nechyporenko, Alina}, title = {Comparison of CNN-Based Architectures for Detection of Different Object Classes}, series = {AI}, volume = {5}, journal = {AI}, number = {4}, publisher = {MDPI}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-19634}, pages = {2300 -- 2320}, year = {2024}, abstract = {(1) Background: Detecting people and technical objects in various situations, such as natural disasters and warfare, is critical to search and rescue operations and the safety of civilians. A fast and accurate detection of people and equipment can significantly increase the effectiveness of search and rescue missions and provide timely assistance to people. Computer vision and deep learning technologies play a key role in detecting the required objects due to their ability to analyze big volumes of visual data in real-time. (2) Methods: The performance of the neural networks such as You Only Look Once (YOLO) v4-v8, Faster R-CNN, Single Shot MultiBox Detector (SSD), and EfficientDet has been analyzed using COCO2017, SARD, SeaDronesSee, and VisDrone2019 datasets. The main metrics for comparison were mAP, Precision, Recall, F1-Score, and the ability of the neural network to work in real-time. (3) Results: The most important metrics for evaluating the efficiency and performance of models for a given task are accuracy (mAP), F1-Score, and processing speed (FPS). These metrics allow us to evaluate both the accuracy of object recognition and the ability to use the models in real-world environments where high processing speed is important. (4) Conclusion: Although different neural networks perform better on certain types of metrics, YOLO outperforms them on all metrics, showing the best results of mAP-0.88, F1-0.88, and FPS-48, so the focus was on these models.}, language = {en} } @article{ZhaoYueZhuetal.2024, author = {Zhao, Shuang and Yue, Zhao and Zhu, Dingcheng and Harberts, Jann and Blick, Robert H. and Zierold, Robert and Lisdat, Fred and Parak, Wolfgang J.}, title = {Quantum Dot/TiO2 Nanocomposite-Based Photoelectrochemical Sensor for Enhanced H2O2 Detection Applied for Cell Monitoring and Visualization}, series = {Small}, volume = {20}, journal = {Small}, number = {45}, publisher = {Wiley}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-19642}, year = {2024}, abstract = {This work exploits the possibility of using CdSe/ZnS quantum dot (QD)-electrodes to monitor the metabolism of living cells based on photoelectrochemical (PEC) measurements. To realize that, the PEC setup is improved with respect to an enhanced photocurrent signal, better stability, and an increased signal-to-noise ratio, but also for a better biocompatibility of the sensor surface on which cells have been grown. To achieve this, a QD-TiO2 heterojunction is introduced with the help of atomic layer deposition (ALD). The heterojunction reduces the charge carrier recombination inside the semiconductor nanoparticles and improves the drift behavior. The PEC performance is carefully analyzed by adjusting the TiO2 thickness and combining this strategy with multilayer immobilizations of QDs. The optimal thickness of this coating is ≈5 nm; here, photocurrent generation can be enhanced significantly (e.g., for a single QD layer electrode by more than one order of magnitude at 0 V vs Ag/AgCl). The resulting optimized electrode is used for hydrogen peroxide (H2O2) sensing with a good sensitivity down to µmolar concentrations, reusability, stability, response rate, and repeatability. Finally, the sensing system is applied to monitor the activity of cells directly grown on top of the electrode surface.}, language = {en} } @article{SchueteBuerklen2025, author = {Sch{\"u}te, Nicolas and B{\"u}rklen, Anna}, title = {A cross-case comparison of the use of shared mobility services in Germany}, series = {Transportation Research Procedia}, volume = {82}, journal = {Transportation Research Procedia}, publisher = {Elsevier}, issn = {2352-1465}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-19865}, pages = {3215 -- 3236}, year = {2025}, abstract = {E-scooter and e-bike shared mobility systems are now available in many cities worldwide as a low-threshold mobility offering for a broad mass. In Germany, e-scooter shared mobility systems have been established for the first time in 2019 in large cities, primarily in inner-city areas. In the meantime, various shared mobility service providers have expanded to small towns and the outskirts of large cities with different supply strategies. Therefore, this paper aims to investigate the different aspects, such as pricing models and parking regulations that affect the usage of such services in the outskirts. For this purpose, the provided data of an e-scooter and e-bike shared mobility service provider has been analyzed. The results show that shared mobility service provider can profit from extending their supply strategies to outskirts due to similar user behaviour compared to inner-city areas. Compared to other outskirts with a lower price, a higher price does not necessarily result in lower demand. Thus, the demand on the outskirts is not necessarily price-driven but rather depends on local factors. In addition, there was a strong tendency to use e-scooters compared to e-bikes. In all case studies, an almost identical relationship between residents and users could be determined.}, language = {en} } @article{PrzymusRykaczewskiMartinSeguraetal.2025, author = {Przymus, Piotr and Rykaczewski, Krzysztof and Mart{\´i}n-Segura, Adri{\´a}n and Truu, Jaak and De Santa Pau, Enrique Carrillo and Kolev, Mikhail and Naskinova, Irina and Gruca, Aleksandra and Sampri, Alexia and Frohme, Marcus and Nechyporenko, Alina}, title = {Deep Learning in Microbiome Analysis: A Comprehensive Review of Neural Network Models}, series = {Frontiers in Microbiology}, volume = {15}, journal = {Frontiers in Microbiology}, publisher = {Frontiers}, issn = {1664-302X}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-19889}, year = {2025}, abstract = {Microbiome research, the study of microbial communities in diverse environments, has seen significant advances due to the integration of deep learning (DL) methods. These computational techniques have become essential for addressing the inherent complexity and high-dimensionality of microbiome data, which consist of different types of omics datasets. Deep learning algorithms have shown remarkable capabilities in pattern recognition, feature extraction, and predictive modeling, enabling researchers to uncover hidden relationships within microbial ecosystems. By automating the detection of functional genes, microbial interactions, and host-microbiome dynamics, DL methods offer unprecedented precision in understanding microbiome composition and its impact on health, disease, and the environment. However, despite their potential, deep learning approaches face significant challenges in microbiome research. Additionally, the biological variability in microbiome datasets requires tailored approaches to ensure robust and generalizable outcomes. As microbiome research continues to generate vast and complex datasets, addressing these challenges will be crucial for advancing microbiological insights and translating them into practical applications with DL. This review provides an overview of different deep learning models in microbiome research, discussing their strengths, practical uses, and implications for future studies. We examine how these models are being applied to solve key problems and highlight potential pathways to overcome current limitations, emphasizing the transformative impact DL could have on the field moving forward.}, language = {en} } @article{KoetheGuskeMartinenetal.2024, author = {K{\"o}the, Alexander and Guske, Oliver and Martinen, Ivan and Hopf, Janik and Worrmann, Paul}, title = {Development and Validation of an Automatic Waypoint Navigation Control System for Watercrafts}, series = {IFAC-PapersOnLine}, volume = {58}, journal = {IFAC-PapersOnLine}, number = {25}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-19673}, pages = {174 -- 179}, year = {2024}, abstract = {This paper presents the development and testing of an automatic control system for waypoint navigation in a solar boat, initially designed for manual operation. It covers the boat's modifications for automation, system identification through step response experiments, and control strategy implementation. The system includes a Base Controller for yaw rate and speed as well as a subsequent Waypoint Path Controller for navigation. Utilizing a nominal dynamic model of the boat, the Base Controller's design emphasizes robustness against parameter uncertainties, while the Waypoint Path Controller follows a conventional approach. The effectiveness of the system is validated with real driving tests.}, language = {en} } @article{LemieszewskiHannebauerRemiszewski2024, author = {Lemieszewski, Łukasz and Hannebauer, Dina and Remiszewski, Grzegorz}, title = {Vulnerability of Wi-Fi wireless network to signal interference}, series = {Journal of Engineering 360 (JoE 360)}, volume = {1}, journal = {Journal of Engineering 360 (JoE 360)}, number = {1/24}, publisher = {The Jacob of Paradies University}, issn = {3071-7507}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-19742}, pages = {58 -- 65}, year = {2024}, abstract = {Wi-Fi networks are often susceptible to signal interference that can disrupt services, intercept sensitive data, and allow unauthorized access. Exploiting this vulnerability, attackers can launch Intentional Electromagnetic Interference (IEMI) attacks or protocol-based attacks. IEMI attacks include, but are not limited to, jamming, which involves the introduction of interference signals in the frequency band used by a given Wi-Fi network, thus disrupting its proper operation. The article presents research on different types of IEMI attacks, aimed at illustrating this type of threat to video transmission from Wi-Fi cameras and discusses methods of protection against this type of attack. The paper examines the methods of jamming the wireless network band, which are used on the distribution methods and the Sweeping Jammer methods that cyclically disrupt all available devices. Based on experiments, it has been confirmed that SOHO devices are highly susceptible to this type of simple attacks and implementing a method to minimize the effects of jamming yields poor results. The simplicity of this type of attack and the high availability of software and hardware tools on the market make the threat highly popular and still dangerous.}, language = {en} } @inproceedings{LindnerLiebchen2019, author = {Lindner, Niels and Liebchen, Christian}, title = {New Perspectives on PESP: T-Partitions and Separators}, series = {19th Workshop on Algorithmic Approaches for Transportation Modelling, Optimization, and Systems (ATMOS 2019)}, booktitle = {19th Workshop on Algorithmic Approaches for Transportation Modelling, Optimization, and Systems (ATMOS 2019)}, publisher = {Schloss Dagstuhl, Leibniz-Zentrum f{\"u}r Informatik}, address = {Dagstuhl}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-20074}, pages = {2:1 -- 2:18}, year = {2019}, abstract = {In the planning process of public transportation companies, designing the timetable is among the core planning steps. In particular in the case of periodic (or cyclic) services, the Periodic Event Scheduling Problem (PESP) is well-established to compute high-quality periodic timetables. We are considering algorithms for computing good solutions and dual bounds for the very basic PESP with no additional extra features as add-ons. The first of these algorithms generalizes several primal heuristics that have been proposed, such as single-node cuts and the modulo network simplex algorithm. We consider partitions of the graph, and identify so-called delay cuts as a structure that allows to generalize several previous heuristics. In particular, when no more improving delay cut can be found, we already know that the other heuristics could not improve either. This heuristic already had been proven to be useful in computational experiments [Ralf Bornd{\"o}rfer et al., 2019], and we locate it in the more general concept of what we denote T-partitions. With the second of these algorithms we propose to turn a strategy, that has been discussed in the past, upside-down: Instead of gluing together the network line-by-line in a bottom-up way, we develop a divide-and-conquer-like top-down approach to separate the initial problem into two easier subproblems such that the information loss along their cutset edges is as small as possible. We are aware that there may be PESP instances that do not fit well the separator setting. Yet, on the RxLy-instances of PESPlib in our experimental computations, we come up with good primal solutions and dual bounds. In particular, on the largest instance (R4L4), this new separator approach, which applies a state-of-the-art solver as subroutine, is able to come up with better dual bounds than purely applying this state-of-the-art solver in the very same time.}, language = {en} } @inproceedings{SteglichVillringerDuemeckeetal.2015, author = {Steglich, Patrick and Villringer, Claus and D{\"u}mecke, Silvio and Padilla-Michel, Yazmin and Casalboni, Mauro and Schrader, Sigurd}, title = {Silicon-On-Insulator Slot-Waveguide Design Trade-Offs}, series = {Proceedings of the 3rd International Conference on Photonics, Optics and Laser Technology : vol. 2}, booktitle = {Proceedings of the 3rd International Conference on Photonics, Optics and Laser Technology : vol. 2}, publisher = {SciTePress}, address = {Set{\´u}bal}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-20104}, pages = {47 -- 52}, year = {2015}, abstract = {Silicon-on-insulator slot-waveguide structures are designed and analysed numerically. We present our theoretical investigation of field confinement factors and effective nonlinear areas for different waveguide structures in order to find optimized geometrical dimensions. It is shown that a slot-waveguide with a height of 220 nm, a slot width of 180 nm and a silicon rail width of 180 nm provides a five times higher field confinement in the cladding region compared to conventional strip-waveguides which explains the high sensitivity of slotwaveguide based label-free bio-sensors.}, language = {en} } @inproceedings{MalisaReiffStephan2025, author = {Malisa, Viktorio and Reiff-Stephan, J{\"o}rg}, title = {Auswirkung der neuen gesetzlichen und normativen Regelungen auf Industrieroboter-Systeme}, series = {Tagungsband AALE 2025 : menschenzentrierte Automation im digitalen Zeitalter}, booktitle = {Tagungsband AALE 2025 : menschenzentrierte Automation im digitalen Zeitalter}, editor = {Reiff-Stephan, J{\"o}rg and J{\"a}kel, Jens and Reichelt, Dirk}, publisher = {Hochschule f{\"u}r Technik, Wirtschaft und Kultur}, address = {Leipzig}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-20130}, pages = {49 -- 59}, year = {2025}, abstract = {EU-Verordnungen und ISO-Normen ver{\"a}ndern die Nutzung von Industrieroboter und beeinflussen deren Integration in effiziente Produktionssysteme. Die rasante Entwicklung der Digitalisierung und die Notwendigkeit einer umfassenden Vernetzung haben Auswirkungen auf die Sicherheit von Maschinen, die Gestaltung von Arbeitspl{\"a}tzen und die Anforderungen an die Ausbildung der Besch{\"a}ftigten. Mit einer Reihe von Gesetzen und Richtlinien schafft die EU einen Ordnungsrahmen f{\"u}r die aktuellen Technologien und versucht, die Rahmenbedingungen f{\"u}r weitere Entwicklungen festzulegen. Gleichzeitig ist die Industrie gefordert, zus{\"a}tzliche Kompetenzen in bestimmten Bereichen der Digitalisierung aufzubauen. Einige Herausforderungen sind jedoch noch zu bew{\"a}ltigen, z. B. wie der Sicherheitsnachweis f{\"u}r in Maschinen integrierte K{\"u}nstliche Intelligenz f{\"u}r autonome mobile Roboter erbracht werden kann, wie die Zertifizierung von Software als Sicherheitselement und dessen Integration in die Automatisierungssysteme und wie die Behandlung von Industrierobotern als vollst{\"a}ndige und nicht mehr als unvollst{\"a}ndige Maschinen erfolgen wird.}, language = {de} } @inproceedings{PadillaMichelLucciCasalbonietal.2015, author = {Padilla-Michel, Yazmin and Lucci, Massimiliano and Casalboni, Mauro and Steglich, Patrick and Schrader, Sigurd}, title = {Mechanical Characterisation of the Four Most Used Coating Materials for Optical Fibres}, series = {Proceedings of the 3rd International Conference on Photonics, Optics and Laser Technology : vol. 1}, booktitle = {Proceedings of the 3rd International Conference on Photonics, Optics and Laser Technology : vol. 1}, editor = {Ribeiro, Paulo A.}, publisher = {SciTePress}, address = {Set{\´u}bal}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-20063}, pages = {96 -- 102}, year = {2015}, abstract = {Optical multimode fibres have a wide variety of applications ranging from industrial to medical use. Therefore, even if they are just used as waveguides or sensors, it is important to characterise the whole fingerprint, including the optical and mechanical properties of such fibres. Since the stiffness/elasticity of a material could influence the optical output of a fibre due to micro-bendings, in this paper we report the calculated Young's Modulus of acrylate, fluorinated acrylate, polyimide and silicone, which are the four most used coating materials for such optical components. The results demonstrate that Young's Modulus does have an impact on the attenuation of propagating light along the optical fibre. However, the refractive index of the coating materials still has a significant impact on the performance of optical fibres.}, language = {en} } @inproceedings{KnotheGeringGloddeetal.2022, author = {Knothe, Thomas and Gering, Patrick and Glodde, Ilona and Ahle, Ulrich and B{\"o}ttger, Jonas and D{\"o}beritz, Niklas}, title = {Model based Configuration of Platforms for Managing Cross- Organizational (Business) Processes}, series = {Interoperability for Enterprise Systems and Applications I-ESA workshops 2022}, booktitle = {Interoperability for Enterprise Systems and Applications I-ESA workshops 2022}, editor = {Zelm, Martin and Boza, Andr{\´e}s and Le{\´o}n, Ramona-Diana and Rodriguez-Rodriguez, Raul}, publisher = {RWTH Aachen}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-18993}, pages = {1 -- 6}, year = {2022}, abstract = {In this contribution interoperability is considered from the perspective of platforms, which have to manage cross-organisational business processes. A model-based approach for configuring a cloud platform for managing complex processes and their dependencies across different organisations is provided. The approach is applied on using FIWARE, which provides a framework of open source software platform components. The core concept is to extend the open source core data model of FIWARE by using the artefacts of an Enterprise model, describing the dependencies of processes, roles, object data and application interfaces. Based on a given use case the principal configuration was applied and validated.}, language = {en} } @article{TillichWolterSchulzeetal.2014, author = {Tillich, Ulrich M. and Wolter, Nick and Schulze, Katja and Kramer, Dan and Br{\"o}del, Oliver and Frohme, Marcus}, title = {High-throughput cultivation and screening platform for unicellular phototrophs}, series = {BMC Microbiology}, volume = {14}, journal = {BMC Microbiology}, number = {239}, issn = {1471-2180}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-6007}, pages = {13}, year = {2014}, abstract = {In this work we describe and test high-throughput methods with the model organism Synechocystis sp. PCC6803. The required technical automation for these processes was achieved with a Tecan Freedom Evo 200 pipetting robot. The cultivation was performed in 2.2 ml deepwell microtiter plates within a cultivation chamber outfitted with programmable shaking conditions, variable illumination, variable temperature, and an adjustable CO2 atmosphere. Each microtiter-well within the chamber functions as a separate cultivation vessel with reproducible conditions. The automated measurement of various parameters such as growth, full absorption spectrum, chlorophyll concentration, MALDI-TOF-MS, as well as a novel vitality measurement protocol, have already been established and can be monitored during cultivation. Measurement of growth parameters can be used as inputs for the system to allow for periodic automatic dilutions and therefore a semi-continuous cultivation of hundreds of cultures in parallel. The system also allows the automatic generation of mid and long term backups of cultures to repeat experiments or to retrieve strains of interest.}, language = {en} } @article{HerzogJaenchen2016, author = {Herzog, Thomas H. and J{\"a}nchen, Jochen}, title = {Adsorption Properties of Modified Zeolites for Operating Range Enhancement of Adsorption Heat Pumps through the Use of Organic Adsorptive Agents}, series = {Energy Procedia}, volume = {91}, journal = {Energy Procedia}, issn = {1876-6102}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-6614}, pages = {155 -- 160}, year = {2016}, abstract = {Faujasite zeolites with the highest possible Al-content and different cations as well as a dealuminated zeolite Y have been chosen to study the impact on the adsorption behavior in view of differed adsorptive agents for heat pumps or thermochemical storages. Our results show advantages and disadvantages for water, methanol or ethanol adsorption due to the structure of the anion skeleton, kind of cations and size of the adsorbat molecule.}, language = {en} } @article{Michalk2013, author = {Michalk, Philip}, title = {Optimizing sales areas of combined transport chains}, series = {LogForum}, volume = {9}, journal = {LogForum}, number = {4}, issn = {1734-459X}, doi = {10.15771/1734-459X_2013_1}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-6252}, pages = {247 -- 253}, year = {2013}, abstract = {Background: Combined transport chains (such as intermodal transport), have certain advantages. The main advantage from customer points of view is the possibility to bundle freight and thereby decrease transport costs. On the other hand, a combined transport chain can cause longer transport times, due to the necessary transshipment processes. Methods: The area around a terminal, in which a combined service has favourable properties to a customer in comparison to a direct transport, can be understood as a sales-area, in which a combined transport product is marketable. The aim of this paper was to find a method to determine the best shape and size of this area. Results and conclusions: The paper at hand lined out a method in order to calculate such a sales area and determine which geographical points around a terminal have an advantage in comparison to a direct transport service.}, language = {en} }