@inproceedings{TannenbergPaulFuenningetal.2025, author = {Tannenberg, Robert and Paul, Martin and F{\"u}nning, Tabea and Schumann, Christoph and Weller, Michael G. and Steglich, Patrick}, title = {Multichannel real-time detection of biomarkers with highly miniaturized photonic microchips}, series = {Proceedings of SPIE : Optical Sensors 2025}, volume = {13527}, booktitle = {Proceedings of SPIE : Optical Sensors 2025}, editor = {Baldini, Francesco and Homola, Jiri and Lieberman, Robert A.}, publisher = {SPIE}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:526-opus4-20456}, year = {2025}, abstract = {The development of novel photonic integrated microchips (PIC) is a promising approach to allow for the convenient detection of key biomarkers in complex matrices through multichannel real-time analysis in a highly compact package. This study reports the successful development and application of a backside released CMOS chip designed for the multichannel real-time detection of biomarkers. Operating at the C-band at approx. 1550 nm, the microchip features three dedicated detection sensors in addition to a reference sensor, enabling simultaneous analysis of multiple biomarkers. The compact and highly miniaturized design of this microchip, with a footprint of just 1 mm², positions it as promising candidate for point-of-care diagnostics and personalized medicine applications. This technology opens a path to transform biomarker detection across various medical fields, offering rapid, reliable, and cost-effective diagnostic solutions. In conclusion, the presented multichannel photonic microchips signify a substantial leap forward in real-time biomarker detection, providing a highly capable platform for future research and clinical applications.}, language = {en} }