TY - CONF A1 - Messaoudi, Hamza A1 - Das, Susanta Kumar A1 - Lange, Janine A1 - Heinrich, Friedhelm A1 - Schrader, Sigurd A1 - Frohme, Marcus A1 - Grunwald, RĂ¼diger T1 - Femtosecond laser induced nanostructuring for surface enhanced Raman spectroscopy N2 - The formation of periodical nanostructures with femtosecond laser pulses was used to create highly efficient substrates for surface-enhanced Raman spectroscopy (SERS). We report about the structuring of silver and copper substrates and their application to the SERS of DNA (herring sperm) and protein molecules (egg albumen). The maximum enhancement factors were found on Ag substrates processed with the second harmonic generation (SHG) of a 1-kHz Ti:sapphire laser and structure periods near the SHG wavelength. In the case of copper, however, the highest enhancement was obtained with long-period ripples induced with at fundamental wavelength. This is explained by an additional significant influence of nanoparticles on the surface. Nanostructured areas in the range of 1.25 mm2 were obtained in 10 s. The surfaces were characterized by scanning electron microscopy, Fast Fourier Transform and Raman spectroscopy. Moreover, the role of the chemical modification of the metal structures is addressed. Thin oxide layers resulting from working in atmosphere which improve the biocompatibility were indicated by vibration spectra. It is expected that the detailed study of the mechanisms of laser-induced nanostructure formation will stimulate further applications of functionalized surfaces like photocatalysis, selective chemistry and nano-biology. KW - laser-induced periodic surface structure KW - surface enhanced Raman spectroscopy KW - SERS KW - metal nanostructure KW - bio-molecule KW - DNA KW - femtosecond laser KW - ultrashort pulse Y1 - 2014 UR - https://opus4.kobv.de/opus4-th-wildau/frontdoor/index/index/docId/1525 UR - https://nbn-resolving.org/urn:nbn:de:kobv:526-opus4-15252 SP - 61 EP - 68 PB - Society of Photo-Optical Instrumentation Engineers (SPIE) ER -