TY - JOUR A1 - Schlegel, Volker A1 - Engels, Andreas A1 - Bifaretti, Stefano A1 - Foitzik, Andreas T1 - Validation of Material Parameters of Collagen Compositions for the Application as a Bioink TI - Materials Science Forum N2 - The novel approach of an individualized medicine affects nowadays various areas of therapeutic treatment. Primarily, these include the application of pharmaceuticals, private point-of-care solutions, surgical procedures as well as steps of rehabilitation. However, beside these existing strategies the development of patient specific models for the training of clinical personal is currently insufficient. Such models are essential to prepare a personalized approach of medical care. One possible solution to address this problem could be the adaption of the established 3d printing technology for the processing of suitable biopolymers. The presented work is focused on the development of a printing system utilizing collagen. Therefore, it is intended to design multiple extrusion heads in accordance with the material parameters. In order to achieve the aspired physiological properties of the final model, a first set of experiments will be performed with several compositions of collagen to validate the fundamental mechanical characteristics. Hereby, the elasticity, thermal stability, force resistance as well as the haptic behaviour are of most interest. Afterwards, these obtained experimental results should be used to simulate the extrusion process and to validate the extruder concepts. In case of a positive evaluation these concepts are realized by using rapid prototyping technologies. Finally, this novel 3d printer will be used to print first organic test structures with collagen. KW - bio-ink KW - bioprinting KW - collagen KW - validation of material parameters Y1 - 2018 UR - https://opus4.kobv.de/opus4-th-wildau/frontdoor/index/index/docId/1876 UR - https://nbn-resolving.org/urn:nbn:de:kobv:526-opus4-18764 SN - 0255-5476 SN - 1662-9752 VL - 941 SP - 2437 EP - 2441 PB - Trans Tech Publications ER -