TY - GEN A1 - Hessel, Franz T1 - Gesundheitsmanagement N2 - Keine Angabe No details KW - Gesundheitsmanagement Y1 - 2012 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. ER - TY - CHAP A1 - Hessel, Franz A1 - Biermann, Janine A1 - Kerkemeyer, Linda A1 - Korff, Lasse A1 - Mostardt, Sarah A1 - Neumann, Anja ED - Wasem, Jürgen T1 - Arzneimittelversorgung T2 - Medizinmanagement: Grundlagen und Praxis N2 - Keine Angabe - No details KW - Medizinische Einrichtung KW - Arzneimittelversorgung Y1 - 2013 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. SP - 355 EP - 391 PB - Medizinisch Wissenschaftliche Verlagsgesellschaft CY - Berlin ER - TY - JOUR A1 - Hessel, Franz T1 - Personalized Medicines: worth the Effort and Investment? JF - Pharmaceutical Executive N2 - Prof. Dr. Franz Hessel questions whether personalized medicine and companion diagnostics are actually enhancing the drug development process. KW - Personalized Medicine KW - Drug Development Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0298-opus4-5479 VL - 11 SP - 2 EP - 6 ER - TY - CHAP A1 - Hessel, Franz T1 - The relevance of the analytic validity of genetic tests in personalized medicine technologies for reimbursement decision making in Germany T2 - EACME Annual Conference, Bochum N2 - Keine Angabe - No details KW - Personalized Medicine KW - Germany Y1 - 2013 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. ER - TY - CHAP A1 - Hessel, Franz T1 - Developing personalized medicine drugs: incentives for pharmaceutical companies T2 - EACME Annual Conference, Bochum N2 - Objectives: Stratification of oncology drug therapy by genetic marker diagnostics can reveal additional patient benefit but also might influence the development process of drug manufacturers. The objective of this study is to identify and describe the most important incentives for pharmaceutical companies to develop personalized medicine drugs. Methods: To describe the main factors influencing the decision making process in the development of personalized medicine drugs we designed a qualitative systemdynamic model. The main factors influencing the process and their priority ranking were determined by systematic literature search, structured expert interviews with pharmaceutical companies, test manufacturers and other key stakeholders such as regulatory bodies, reimbursement decision makers and payers. The model was build with the Consideo iModeler software package. Results: In contrast to small companies big international companies constantly look for suitable companion diagnostic tests to select subgroups of high responder. The most important key factor for market success is the extent of clinical efficacy in comparison with competitors respectively the current treatment standard. Stratification of patient populations according to treatment response or frequency of adverse events using biomarker is regarded to increase clinical efficacy of the target indication. The test performance is important due to unsolved safety issues although not regarded as crucial for the success of the drug. In contrast to other stakeholders pharmaceutical companies did not consider personalized medicine to relevantly decrease development costs or marketing efforts respectively to increase the price potential for new drugs. A low prevalence of the remaining patient population after testing is not irrelevant but it is not seen as a factor which might lead to a stop of the development of a new drug by pharmaceutical companies. Conclusions: Genetic stratification is seen as a breakthrough in cancer therapy by pharmaceutical companies and physicians. Due to the current need for improvement of approval and reimbursement processes for personalized medicine approaches in oncology especially in Europe future sales are more difficult to predict. KW - Personalized Medicine KW - Pharmaceutical Companies Y1 - 2013 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. ER - TY - JOUR A1 - Moock, Jörn A1 - Hessel, Franz A1 - Ziegeler, Diana A1 - Kubiak, Thomas A1 - Kohlmann, Thomas T1 - Development and Validation of the Insulin Treatment Experience Questionnaire (ITEQ) JF - The Patient N2 - Objectives: To develop and psychometrically evaluate a domain-specific questionnaire to assess subtle but clinically relevant differences in treatment experiences and satisfaction over a wide range of currently available insulin therapy regimens. The study focussed on patients with type 2 diabetes mellitus and placed particular attention on the impact of different forms of insulin therapy on diabetes self-management. Methods: The development of the Insulin Treatment Experience Questionnaire (ITEQ) was conducted in three steps: (i) a qualitative phase to generate relevant items and identify relevant domains; (ii) a pilot study to reduce the number of generated items; and (iii) a validation study to assess major psychometric properties of the final ITEQ version. Results: The final version of the questionnaire comprised 28 items with the subscales ‘leisure activities’ (four items), ‘psychological barriers’ (two items), ‘handling’ (five items), ‘diabetes control’ (six items), ‘dependence’ (five items), ‘weight control’ (three items), ‘sleep’ (two items), and one further item assessing general treatment satisfaction. The subscales’ internal consistencies (Cronbach’s alpha) ranged from 0.52 to 0.83. Motivated by the homogenous structure of inter-scale-correlations (range 0.10–0.46), a summary composite score was calculated (alpha = 0.86). Construct validity showed statistically significant correlations with other scales (ITEQ vs the Problem Areas in Diabetes [PAID] questionnaire total score −0.60, ITEQ vs the Diabetes Treatment Satisfaction Questionnaire [DTSQ] total score 0.52). Conclusion: The newly developed ITEQ displayed satisfactory to good psychometric properties, thereby allowing the assessment of everyday life experience and treatment satisfaction in patients with insulin-treated type 2 diabetes. Additional research is needed to assess test-retest reliability and sensitivity to change. KW - Diabetis Self-Management KW - Diabetis Mellitus Y1 - 2010 N1 - Online: https://www.researchgate.net/publication/233507832_Development_and_Testing_of_the_Insulin_Treatment_Experience_Questionnaire_ITEQ VL - 3 IS - 1 SP - 45 EP - 58 ER - TY - JOUR A1 - Hessel, Franz A1 - Bramlage, Peter A1 - Wasem, Jürgen A1 - Mitzner, Steffen R. T1 - Cost effectiveness of the artifical liver support system MARS in patients with acute-on-chronic liver failure JF - European Journal of Gastroenterology & Hepatology N2 - For patients with an acute exacerbation of chronic liver failure (ACLF), the molecular adsorbent recirculating system (MARS) can result in a prolongation of life, but data on costs and cost-effectiveness are lacking. A health economic evaluation of a prospective controlled cohort trial in patients with ACLF not eligible for liver transplantation with 3 years follow-up and consecutive modelling of long-term costs, outcomes and cost-effectiveness was conducted. Costs were calculated from the perspective of the German health-care system. One hundred and forty-nine patients with ACLF were included of which 67 (44.9%) were treated with MARS and 82 (55.1%) assigned to the control group. Mean survival was 692 days in MARS-treated patients (33% survival after 3 years) and 453 days in control patients (15% after 3 years, logrank P = 0.022). MARS patients gained 0.66 [95% confidence interval (CI): -0.12 to 1.46] life years (LYs), determined by the bootstrap method. The mean cost difference was 19.835 euro (95% CI: 13.308-25.429) with 35639 euro for MARS-treated patients and 15804 euro for controls. Incremental costs per LY gained were 29.985 euro (95% CI: 9.441-321.761) and 43.040 euro (95% CI: 13.551-461.856) per quality-adjusted LY gained. There is an acceptable cost-effectiveness of MARS, compared with other medical technologies presently reimbursed. Randomized controlled trials with sufficient sample size are necessary before a final recommendation for MARS can be given. KW - Health Economics KW - Cost Benefit Analysis Y1 - 2010 N1 - Online: https://www.researchgate.net/publication/26830926_Cost-effectiveness_of_the_artificial_liver_support_system_MARS_in_patients_with_acute-on-chronic_liver_failure VL - 22 IS - 2 SP - 213 EP - 220 ER - TY - JOUR A1 - Reinhold, Thomas A1 - Brüggenjürgen, Bernd A1 - Schlander, Michael A1 - Rosenfeld, Stephanie A1 - Hessel, Franz A1 - Willich, Stefan N. T1 - Economic analysis based on multinational studies: methods for adapting findings to national contexts JF - Journal of Public Health N2 - Background: Health economic parameters are increasingly considered as variables in health care decisions, but decision makers are interested in country-specific evaluations. However, a large number of studies are performed in foreign countries or in a multinational setting, which limits the transferability to a single nation’s context. Objective: The present analysis summarises several of the most common international methods for generating health economic analyses based on clinical studies from different settings. Methods: A narrative literature review was performed to identify potential reasons for limited transferability of health economic evaluation results from one country to another. Based on these results, we searched the methodological literature for analytic approaches to handle the restrictions. Additionally we describe the possibility of transferring foreign economic study results to the country of interest by matching trial data with routine data of national databases. Results: The main factors for limited transferability of health economic findings were found in country-specific differences in resource consumption and the resulting costs. These differences are affected by a number of influencing cofactors (demography, epidemiology and individual patient’s factors) and the overall health care system structures (e.g. payment systems, health provider incentives). However, despite the limitations country-specific health economic assessments could be realised using the pooled/split analyses approach, some statistical approaches and modelling approaches. Conclusion: A variety of methods for identifying and adjusting country-specific differences in costs, effects and cost-effectiveness was established during the past decades. Multinational studies will continue to play a crucial role in the evaluation of cost-effectiveness at national levels. It seems likely that the growing interest in multinational studies will lead to continued developments in adaptation methods. KW - International Adaption KW - Cost-Effectiveness KW - Economic Evaluation Y1 - 2010 N1 - Online: https://www.ssoar.info/ssoar/handle/document/20369 VL - 18 IS - 4 SP - 327 EP - 335 ER - TY - GEN A1 - Hessel, Franz T1 - Knorpelzellentransplantation aus Sicht der Gesundheitsökonomie und Versorgungsforschung N2 - Keine Angabe No details KW - Transplantation KW - Gesundheitsökonomie KW - Versorgungsforschung Y1 - 2012 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. ER - TY - GEN A1 - Schermuly, Carsten C. T1 - Die systematische Verhaltensbeobachtungsmethode in der Arbeits- und Organisationspsychologie: Chancen, Risiken und neue Entwicklungen N2 - Kommunikationsprozesse von Angesicht zu Angesicht sind alltägliche und allgegenwärtige Aspekte der menschlichen Existenz. Dies gilt nicht nur für die Freizeit sondern auch für das Arbeitsleben und insbesondere für die Arbeit in Teams. Die Güte der Kommunikation in Organisationen sowie Teams und die Konsequenzen dieser für das Beziehungsgefüge haben erhebliche Auswirkungen auf den Unternehmenserfolg. Die empirische Herausarbeitung der Verhaltens komponenten, Strukturmerkmale und Wirkfaktoren von Kommunikationsepisoden in Organisationen und Teams ist deshalb besonders wichtig. Mit adäquaten Methoden muss analysiert werden, wie in Teams kommuniziert wird und welche Konsequenzen daraus erwachsen. In diesem Vortrag werden die Hintergründe sowie Vor- und Nachteile der systematischen Verhaltensbeobachtungsmethode für die Analyse von Kommunikationsprozessen in Arbeitsteams dargestellt. Es werden verschiedene Studien vorgestellt, die Beobachtungsdaten nutzen sowie neue methodische Entwicklungen wie das Instrument zur Kodierung von Diskussionen(IKD, Schermuly & Scholl, 2011), die eine softwaregestützte Beobachtung und Analyse von Kommunikationsprozessen möglich machen. KW - Verhaltensbeobachtung KW - Arbeitspsychologie KW - Organisationspsychologie Y1 - 2012 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. ER - TY - CHAP A1 - Chlebus, Krysztof A1 - Hahnenkamp, Klaus A1 - Stricker, Monika A1 - Ternès, Anabel T1 - Fachkräftesicherung in Life Sciences und Gesundheitswirtschaft N2 - Keine Angaben No details KW - Fachkräfte KW - Life Science KW - Gesundheitsmanagement Y1 - 2014 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. ER - TY - JOUR A1 - Ternès, Anabel A1 - Towers, Ian A1 - Shauvencka, N. T1 - Testing the Impact of Gamification on the Interest in Urban Planning JF - Journal of the Worldwide Forum on Education and Culture N2 - Keine Angabe No details KW - Gamification KW - Urban Planning Y1 - 2014 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. VL - 5 IS - 1 SP - 63 EP - 84 ER - TY - CHAP A1 - Stantchev, Vladimir T1 - Towards Ambient IT in Healthcare N2 - Keine Angabe No details KW - Ambient IT KW - Healthcare Y1 - 2015 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. ER - TY - CHAP A1 - Stantchev, Vladimir T1 - The Perspectives for IT in Healthcare: the Case of Spain and Germany N2 - Keine Angabe No details KW - IT KW - Healthcare Y1 - 2015 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. ER - TY - CHAP A1 - Stantchev, Vladimir T1 - PrevenTAB: Towards Ambient IT in Healthcare N2 - Keine Angabe No details KW - Ambient IT KW - Healthcare Y1 - 2015 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. ER - TY - JOUR A1 - Hamed, Sara A1 - Ternès, Anabel A1 - El-Bassiouny, Noha T1 - Evidence-Based Designs and Transformative Service Research Application for Achieving Sustainable Healthcare Services: a Developing Country Perspective JF - Journal of Cleaner Production N2 - Keine Angabe No details KW - Healthcare KW - Sustainability Y1 - 2015 N1 - Online: https://www.researchgate.net/publication/308417368_Evidence-Based_Design_and_Transformative_Service_Research_Application_for_Achieving_Sustainable_Healthcare_Services_A_Developing_Country_Perspective ER - TY - CHAP A1 - Stantchev, Vladimir T1 - Requirements Engineering for Risk Management Solutions in Hospitals N2 - Keine Angabe No details KW - Risk Management KW - Service Computing Y1 - 2015 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. ER - TY - THES A1 - Mezger, Leyan T1 - Challenging dominating beauty ideals? A content analysis of body positive accounts on Instagram N2 - In the last few years, the body-positive movement, which challenges unrealistic beauty standards by promoting self-love and acceptance towards diverse bodies, has grown in popularity specifically on Instagram. This has generated mixed resonance about the movement. The present study aimed at understanding the criticism of body positivity being co-opted by corporations and reinforcing beauty ideals by examining body positive messages and their impact. This thesis provides a content analysis of 150 Instagram posts of 15 body positive influencers on Instagram while focusing on commercialistic aspects and follower interaction. The results showed that body positive content usually depicted broad ranges of body sizes but focused less on communicating positive body image themes. It was found that commercialism is majorly integrated into the accounts and follower interaction is higher if the individual showed more skin or self-objectified poses. KW - Social Media KW - Body Positivity KW - Instagram KW - Beauty ideal KW - Beauty standard KW - Creative Industries Management Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0298-opus4-11940 N1 - Das Einverständnis zur Veröffentlichung liegt der Bibliothek vor. Consent for publication has been given to the library. ER - TY - THES A1 - Lück, Anne T1 - Fitness-Werbung für Nahrungsergänzungsmittel : In welchen Rollentypologien werden Männer und Frauen von den Herstellern Qi² und MyProtein dargestellt? N2 - Immer mehr neue Proteinprodukte kommen auf den Markt: Proteinjoghurts und Quarks, Müslis und Shakes. An kaum einer Supermarktkasse findet man keine Proteinriegel. Ein Fitnesstrend zeigt sich sowohl in den steigenden Zahlen der Fitnessstudio Mitglieder, als auch in boomenden Umsatzzahlen im Bereich der Fitnessprodukte und Nahrungsergänzungsmittel. [...] Problematisch an dieser gesellschaftlichen Entwicklung kann sein, dass der Fitnesstrend potenziell einhergeht mit einem wachsenden Selbstoptimierungswunsch der Menschen, die sich an gesellschaftlichen Schönheitsidealen orientieren. Dies steht möglicherweise im engen Zusammenhang mit geschlechtsspezifischen Rollendarstellungen im Marketing. Inwieweit sich Sexismus in der Fitness-Werbung für Nahrungsergänzungsmittel widerspiegelt, soll in der Bachelorarbeit beispielhaft anhand von zwei Proteinprodukt-Marken untersucht werden. KW - Journalismus und PR KW - Fitness-Branche KW - Geschlechterforschung KW - Social Media Marketing KW - Werbung KW - Sexismus KW - Nahrungsergänzungsmittel Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0298-opus4-12043 N1 - Das Einverständnis zur Veröffentlichung des Volltextes liegt der Bibliothek vor. Consent to publish the full text has been given to the library. ER - TY - JOUR A1 - Hamed, Sara A1 - El-Bassiouny, Noha A1 - Ternès, Anabel T1 - Evidence-Based Design and Transformative Service Research Application for Achieving Sustainable Healthcare Services: A Developing Country Perspective JF - International Journal of Pharmaceutical and Healthcare Marketing N2 - Patients look carefully for detailed information pertaining to their expectations before selecting a healthcare service provider. In order to meet these expectations and achieve patient wellbeing, healthcare service providers should understand more the importance of sustainable hospital servicescape designs for their patients jointly with the common focus on functionality in the medical procedures. The importance of the servicescape in creating a healing environment for patients has been shown through Evidence-Based Design research. The rising importance of consumer wellbeing and sustainability is shown in Transformative Service Research. The aim of this study is to bridge the gap between the two research fields to develop guidelines for future hospital servicescapes in developing countries. The application of this study is on Egypt because of the deterioration of its healthcare service provision. Results indicate that patients find plants and greenery, safety, and single rooms as the most important aspects to improve their wellbeing state. These results indicate that patients want to receive their basic treatment in a healing environment without mistakes. The achieved results act as guidelines for improving servicescapes of hospitals in Egypt and other developing countries. This contributes to hospital managers by offering a more sustainable competitive advantage. Contributions for future research are related to testing the effect of the servicescape on patient wellbeing by combining all servicescape aspects in one model. KW - Healthcare KW - Transformative service research KW - Evidence-based design Y1 - 2016 SN - 1750-6123 N1 - Online: https://www.researchgate.net/publication/303869203_Evidence-based_design_and_transformative_service_research_for_the_healthcare_in_hospitals_Setting_the_research_agenda VL - 10 IS - 2 SP - 214 EP - 229 PB - Emerald CY - Bradford ER - TY - BOOK A1 - Ghadiri, Argang A1 - Ternès, Anabel A1 - Peters, Theo T1 - Trends im Betrieblichen Gesundheitsmanagement BT - Ansätze aus Forschung und Praxis N2 - Dieser Herausgeberband schafft einen Überblick darüber, wie Betriebliches Gesundheitsmanagement neue Trends aus der Unternehmenspraxis und Forschung aufgreifen und erfolgreich umsetzen kann. Experten aus Theorie und Praxis liefern dazu Grundlagen sowie bisher selten berücksichtigte Instrumente der Forschung im Betrieblichen Gesundheitsmanagement. Sie geben praxisnahe Anregungen sowie Anleitungen, die Unternehmen leicht umsetzen können. Zielgruppen sind Unternehmen, Manager, aber auch Berater, Auditoren und alle, die an dem Thema Gesundheit in Unternehmen interessiert sind. Der Inhalt • Teil 1: „Organisation“ mit Themen wie Motivation und Sensibilisierung für Maßnahmen im Gesundheitsmanagement, psychische Gefährdungsbeurteilungen und neue Arbeitsformen • Teil 2: „Technologie“ mit Themen wie E-Health in der Gesundheitsförderung, Mind Machines und Neurofeedback • Teil 3: „Mensch“ mit Themen wie Mimikmeditation, gesunde Führung und Interkulturalität Die Herausgeber Argang Ghadiri (M.Sc.) arbeitet als Wissenschaftlicher Mitarbeiter an der Hochschule Bonn-Rhein-Sieg im Fachbereich Wirtschaftswissenschaften und promoviert an der Mercator School of Management der Universität Duisburg-Essen. Prof. Dr. Anabel Ternès ist Geschäftsführerin des Instituts für Nachhaltiges Management. Sie leitet die Studiengänge International Communication Management und E-Business an der SRH Hochschule Berlin. Prof. Dr. Theo Peters lehrt Betriebswirtschaftslehre, insbesondere Führung und Projektmanagement, an der Hochschule Bonn-Rhein-Sieg und leitet den Studienschwerpunkt Gesundheitsmanagement. KW - Gesundheitsförderung KW - Unternehmen Y1 - 2016 SN - 978-3-658-07977-2 N1 - Buch verfügbar in der Bibliothek der SRH Hochschule Berlin, Signatur QP420 3. Book available in the library oft he SRH Hochschule Berlin, shelf mark QP420 3. PB - Springer CY - Wiesbaden ER - TY - GEN A1 - Ternès, Anabel T1 - Trends im Betrieblichen Gesundheitsmanagement BT - Gesunde und motivierte Mitarbeiter sind der Schlüssel für nachhaltigen Unternehmenserfolg N2 - Der Begriff „Betriebliches Gesundheitsmanagement“ wird in der betrieblichen Praxis oftmals unterschiedlich aufgefasst und verwendet; auch in der wissenschaftlichen Literatur existiert hierzu kein einheitliches Begriffsverständnis. Eine oft zitierte und für den Einstieg in die Thematik geeignete Definition liefern Badura et al.(2010,S.33): „Unter Betrieblichem Gesundheitsmanagement verstehen wir die Entwicklung betrieblicher Strukturen und Prozesse, die die gesundheitsförderliche Gestaltung von Arbeit und Organisation und die Befähigung zum gesundheitsfördernden Verhalten der Mitarbeiterinnen und Mitarbeiter zum Ziel haben.“... KW - Lebensqualität KW - Leistungsfähigkeit KW - Gesunde Arbeit Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0298-opus4-10730 SP - 20 EP - 25 ER - TY - JOUR A1 - Icks, Andrea A1 - Chernyak, Nadja A1 - Bestehorn, Kurt A1 - Brüggenjürgen, Bernd A1 - Bruns, J. A1 - Damm, Oliver A1 - Dintsios, Charalabos-Markos A1 - Dreinhöfer, Karsten E. A1 - Gandjour, Afschin A1 - Gerber-Grote, Andreas A1 - Greiner, Wolfgang A1 - Hermanek, P. A1 - Hessel, Franz A1 - Heymann, Romy A1 - Huppertz, Eduard A1 - Jacke, Christian Olaf A1 - Kächele, H. A1 - Kilian, R. A1 - Klingenberger, D. A1 - Kolominsky-Rabas, P. A1 - Krämer, Heike U. A1 - Krauth, Christian A1 - Lüngen, M. A1 - Neumann, T. A1 - Porzsolt, Franz A1 - Prenzler, A. A1 - Pueschner, F. A1 - Riedel, R. A1 - Rüther, A. A1 - Salize, H. J. A1 - Scharnetzky, E. A1 - Schwerd, W. A1 - Selbmann, Hans Konrad A1 - Siebert, H. A1 - Stengel, Dirk A1 - Stock, Stephanie A1 - Völler, Heinz A1 - Wasem, Jürgen A1 - Schrappe, Martin T1 - Methoden der gesundheitsökonomischen Evaluation in der Versorgungsforschung JF - Das Gesundheitswesen N2 - Das Deutsche Netzwerk Versorgungsforschung e. V. (DNVF e. V.) hat am 30.08.2010 getragen von den genannten im DNVF organisierten Fachgesellschaften und Organisationen, das Memorandum III „Methoden für die Versorgungsforschung” Teil 2 verabschiedet, das in dieser Zeitschrift publiziert wurde [Gesundheitswesen 2010; 72: 739-748]. Die vorliegende Publikation fokussiert auf die Methodik der ökonomischen Evaluation der Gesundheitstechnologien bzw. Interventionen und stellt eine Vertiefung zu dem Memorandum III „Methoden für die Versorgungsforschung” Teil 2 dar. Zunächst werden allgemeine methodische Standards gesundheitsökonomischer Evaluationen, d. h. Studien, die die Kosten-Nutzen Relation (Wirtschaftlichkeit) von Interventionen untersuchen, kurz dargestellt. Um Versorgungsrealität adäquat zu reflektieren, müssen zur Ermittlung der Interventionskosten und -effekte oft mehrere Datenquellen, z. B. Wirksamkeitsstudien, Register, administrative Quellen usw., verwendet werden. Daher werden für die gesundheitsökonomischen Evaluationen im Rahmen der Versorgungsforschung potenziell geeignete Datenquellen vorgestellt, ihre Vorteile und Limitationen genannt. Anschließend wird der Weiterentwicklungsbedarf der Methodik im Hinblick auf die Datenerhebung, und -auswertung sowie die Kommunikation und Dissemination der Ergebnisse diskutiert. KW - Gesundheitsökonomie KW - Ökonomische Evaluation KW - Versorgungsforschung Y1 - 2010 N1 - Online: https://www.researchgate.net/publication/46414905_Methoden_der_gesundheitsokonomischen_Evaluation_in_der_Versorgungsforschung VL - 72 IS - 12 SP - 917 EP - 933 ER - TY - JOUR A1 - Neumann, Anja A1 - Jahn, Rebecca A1 - Diehm, Curt A1 - Driller, Elke A1 - Hessel, Franz A1 - Ommen, Oliver A1 - Pfaff, Holger A1 - Siebert, Uwe A1 - Pittrow, David A1 - Wasem, Jürgen T1 - Outcomes of medical management of peripheral arterial disease in general practice: follow-up results of the PACE-PAD Study JF - Journal of Public Health N2 - Peripheral arterial disease (PAD), a marker of elevated vascular risk, is highly prevalent in general practice. We aimed to investigate patient characteristics and outcomes of PAD patients treated according to the guidelines versus those who were not. Methods. PACE-PAD was a multicentre, cluster - randomised prospective, longitudinal cohort study of patients with PAD in primary care, who were followed-up for death or vascular events over 18 months. Guideline-orientation was assumed, if patients received anti¬coagu¬lant/antiplatelet therapy, exercise training, and (if applicable) advice for smoking cessation and therapy of diabetes mellitus, hypertension, or hypercholesterolemia, respectively. Results. The 5099 PAD patients (mean age 68.0 ± 9.0 years, 68.5% males) who were followed-up were in Fontaine stages I, IIa, IIb, III, and IV in 22.5%, 34.6%, 30.1%, 7.8%, and 3.5% (1.5% not specified). Comprehensive guideline orientation was reported in 28.4% only, however, patients in lower Fontaine stages received more often guideline-oriented therapy (I: 30.3%; IIa: 31.6%, IIb: 29.1%, III: 9.8%, IV: 18.0%). During 18 months, 457 patients died (224 due to cerebrovascular or coronary deaths), 319 had instable angina pectoris, 116 myocardial infarction, and 140 an ischemic stroke event. In total, 24% of patients had experienced any vascular event (19.1% a first event). Event rates did not differ between patients treated according to guidelines, and those who were not. Conclusion. The present PAD cohort was a high-risk sample with an unexpectedly high rate of deaths and vascular events. While physicians appear to focus on the treatment of individual risk factors, rates of comprehensive PAD management in line with guideline recommendations are still suboptimal. Factors contributing to the lacking difference between outcomes in the guideline-oriented and non-guideline-oriented groups may comprise low treatment intensity or other reasons for unsatisfactory effect of treatment, misclassification of events, patient's non-compliance with therapy. KW - Guideline Orientation KW - Peripheral Arterial Disease KW - Observational Study Y1 - 2010 N1 - Online: https://www.ssoar.info/ssoar/handle/document/23313 VL - 18 SP - 523 EP - 532 ER - TY - CHAP A1 - Ternès, Anabel A1 - Kavalera-Lodge, W. T1 - Arbeitnehmergesundheit als Chefsache?: Warum Arbeitnehmergesundheit langfristig nur gelingen kann, wenn die Kommunikation im Unternehmen stimmt ; innovativer Ansatz zur Arbeitnehmergesundheit auf der Grundlage eines Pilotprojektes mit Studie im Europäischen Patentamt T2 - Corporate Health Jahrbuch2012: Betriebliches Gesundheitsmanagement in Deutschland N2 - Keine Angabe No details KW - Arbeitnehmergesundheit KW - BGM KW - Betriebliches Gesundheitsmanagement Y1 - 2012 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. SP - 110 EP - 114 PB - Hoehner Research & Consulting Group CY - Bonn ER - TY - JOUR A1 - Glasberg, Ronald A1 - Hartmann, Michael A1 - Draheim, Michael A1 - Tamm, Gerrit A1 - Hessel, Franz T1 - Risks and Crises for Healthcare Providers: the Impact of Cloud Computing JF - The Scientific World Journal N2 - We analyze risks and crises for healthcare providers and discuss the impact of cloud computing in such scenarios. The analysis is conducted in a holistic way, taking into account organizational and human aspects, clinical, IT-related, and utilities-related risks as well as incorporating the view of the overall risk management. KW - Healthcare KW - Cloud Computing Y1 - 2014 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0298-opus4-9695 ER - TY - JOUR A1 - Vetter, Laura A1 - Gockel, Christine T1 - Can’t buy me laughter : Humour in organisational change JF - Gruppe. Interaktion. Organisation. Zeitschrift für Angewandte Organisationspsychologie (GIO) N2 - This article reflects upon the potential role of humour during an organisational change process. We focus on three facets that are of special importance during change: coping with the change, resisting the change, and leading the change. For each facet, we present relevant quantitative and qualitative studies; and in a final section, we derive implications for employees, leaders, and organisations. In regards to coping with change, we focus on the stress-buffering effects of humour. High-humour individuals maintain higher levels of positive affect in stressful situations and appraise a potentially stressful event as a positive challenge rather than a threat. In regards to resisting change, we show that aggressive humour can be an indicator of serious distress and a means to express resistance towards authority or aspects of the change process. In regards to leading change, we point out how effective leaders may utilise humour to manage followers’ emotions in order to increase positive affect and to reduce perceived threat associated with change. We conclude by suggesting how humour can be used as a diagnostic tool, to foster a humour-supportive climate, to improve communication strategies, and to support an error management culture. KW - Organisational change KW - Leadership KW - Resistance Y1 - 2016 N1 - Online: https://www.researchgate.net/publication/310780092_Can't_buy_me_laughter_-_Humour_in_organisational_change VL - 47 IS - 4 SP - 313 EP - 320 PB - Springer Fachmedien CY - Wiesbaden ER - TY - CHAP A1 - Hessel, Franz T1 - Im Spannungsfeld zwischen Gesundheitsförderung und Ressourcenknappheit BT - Gesundheitsheitsökonomische Aspekte des Betrieblichen Gesundheitsmanagement T2 - Trends im Betrieblichen Gesundheitsmanagement N2 - Ökonomische Faktoren spielen bei der Ausgestaltung des Betrieblichen Gesundheitsmanagements eine wichtige Rolle. Zahlreiche und regelmäßige Statistiken zu Absentismus und Präsentismus durch berufsbedingte Erkrankungen weisen auf die Notwendigkeit eines Betrieblichen Gesundheitsmanagements für Unternehmen hin. Doch die Auswirkungen gehen über die Konsequenzen für die Unternehmen weit hinaus. Diese Nutzen- und Kostenkonsequenzen eines Betrieblichen Gesundheitsmanagements für die betroffenen Patienten, die Gesellschaft und die Krankenkassen werden in gesundheitsökonomischen Analysen dargestellt. Trotz des hohen gesellschaftlichen Potenzials eines Betrieblichen Gesundheitsmanagements und der grundsätzlichen Eignung der methodischen Ansätze der Gesundheitsökonomie auch zur Untersuchung dieser Maßnahmen finden sich nur wenige Studien zur medizinischen Wirksamkeit und so gut wie keine gesundheitsökonomischen Evaluationen zu unternehmensbasierten Präventionskonzepten. Dieser Beitrag fasst die wesentlichen geeigneten methodischen Konzepte der Gesundheitsökonomie sowie den Stand der Literatur zu gesundheitsökonomischen Studien von Maßnahmen des Betrieblichen Gesundheitsmanagements zusammen. KW - Gesundheit KW - Krankheiten Y1 - 2016 N1 - Buch verfügbar in der Bibliothek der SRH Berlin School of Management and Technology, Signatur QP420 3. Book available in the library oft he SRH Berlin School of Management and Technology, shelf mark QP420 3. SP - 43 EP - 57 PB - Springer CY - Wiesbaden ER - TY - JOUR A1 - Hessel, Franz T1 - Genetisch stratifizierende Medizin in der Onkologie BT - Individualisierte Medizin. Chancen und Grenzen zukünftiger Patientenbehandlung. JF - Blickpunkte Mensch Gesellschaft Sicherheit N2 - Keine Angabe - No details Y1 - 2015 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Full text due to copyright not available. IS - 4 SP - 10 EP - 12 ER - TY - CHAP A1 - Hessel, Franz T1 - The Relevance of the Analytic Validity of Genetic Biomarker Tests in Personalised Medicine in Oncology BT - critical perspectives T2 - The Ethics Personalised Medicine N2 - A crucial attribute of genetically stratifying personalised medicine technologies is the combination of a biomarker test (or a set of more than one) and a therapeutic decision which is made according to the test results. The biomarker test – often called a ‘companion diagnostic’ – is an essential part of the personalised medicine treatment strategy. The US FDA (Food and Drug Administration) approval agency even stated in a recent reflection paper that it would not approve a new drug without the companion biomarker test if a marker is known (FDA, 2011). KW - Health Y1 - 2015 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright no available. SP - 187 EP - 208 PB - Ashgate CY - Farnham ER - TY - CHAP A1 - Noweski, Michael A1 - Walendzik, Anke A1 - Hessel, Franz A1 - Jahn, Rebecca A1 - Wasem, Jürgen T1 - Approval and Reimbursement of Personalised Drugs: Interim Results of the Adjustment Process BT - critical perspektives T2 - The Ethics of Personalised Medicine N2 - According to drug manufacturers, the pharmaceutical industry is suffering from an ‘innovation crisis’. Nowadays, the development of new products requires significantly more investment than in the past. Most of the simple but useful chemical entities seem to have been discovered already. Moreover, many topselling drugs lose their patent protection (‘patent cliff ’) and, subsequently, prices and sales of the original drug are undermined by competing generics. Producers try to compensate for the loss of sales by launches of new molecular entities (Jimenez, 2012). However, the new compounds generate fewer sales. As market observers calculated, new products launched in the period from 2001 to 2005 achieved annual average sales of USD 208 million after three years. New products of the period from 2006 to 2010 reached only USD 143 million (Rockoff and Winslow, 2013). Development of a drug which yields more than a billion USD per year (‘blockbuster’) succeeds less often. Drugs combined with biomarker-based diagnostic tests, stratifying patients into groups characterised by different drug reactions, appear to be one way out of trouble, because a new generation of patented products seems attainable (Scollen and Phelan, 2014). KW - Medicine KW - Drugs Y1 - 2015 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright no available. SP - 199 EP - 209 PB - Ashgate CY - Farnham ER - TY - CHAP A1 - Schildmann, Jan A1 - Böttcher, Miriam A1 - Gabriel, Maria A1 - Ganser, Arnold A1 - Hessel, Franz A1 - Gottwald, Sina T1 - "Personalised medicine": Multidisciplinary perspectives and interdisciplinary recommendations on a framework for future research and practice BT - critical perspectives T2 - The Ethics of Personalised Medicine N2 - ‘Personalised medicine’ (PM) has raised great hopes and expectations among researchers, patients, health-care providers and politicians in past years. Although the term ‘person’ in PM suggests an approach of medicine which takes into account psychosocial and value aspects of the patient as human being, most articles refer to PM as strategies limited to biological features of individuals which are used to stratify patient groups for the purposes of prevention, diagnosis and treatment of disease. KW - Medicine Y1 - 2015 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright no available. SP - keine Angabe EP - keine Angabe PB - Ashgate CY - Farnham ER - TY - CHAP A1 - Hessel, Franz T1 - HTA in Personalized Medicine Technologies BT - Technological, Clinical and Commercial Aspects T2 - Biomarker Validation N2 - Beyond the proof of efficacy and safety for approval purposes health technology assessment (HTA) is a more comprehensive evaluation of all relevant short- and long-term consequences of the application of a specific medical technology. HTA is performed for the purpose of reimbursement decision making. It covers clinical, societal, economic, ethical and legal aspects based on the available scientific evidence. Although there are some special issues to be considered all principles of HTA are equally valid for the evaluation of biomarker tests and personalized medicine technologies. All requirements of evidence-based medicine remain and causality should and could only be demonstrated with high-quality controlled studies, preferably with randomized design. The multimodality of the intervention and by tendency smaller sample sizes lead to an increased amount of uncertainty. Besides the test strategy, itself also questions of test or sample quality, laboratory size, or the platform used, and the specific technology must be taken into consideration. Economic evaluations should also include these aspects. In summary the fundamental principles of HTA and health economic evaluation are also valid and feasible for the evaluation of personalized medicine and genetic biomarker tests, but careful adaptations of the existing HTA and health economic guidelines are required. KW - Medicine KW - Technology Y1 - 2015 N1 - Online: https://www.researchgate.net/publication/300912255_HTA_in_Personalized_Medicine_Technologies SP - 95 EP - 106 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Schermuly, Carsten C. A1 - Meyer, Bertolt T1 - Good relationships at work: The effects of Leader–Member Exchange and Team–Member Exchange on psychological empowerment, emotional exhaustion, and depression JF - Journal of Organizational Behavior N2 - Emotional exhaustion and depression pose a threat to employees' psychological health. Social relationships at work are important potential buffers against these threats, but the corresponding psychological processes are still unclear. We propose that the subjective experience of high-quality relationships with supervisors (i.e., Leader–Member Exchange [LMX]) is one of the protective factors against psychological health issues at work and that this effect is mediated by psychological empowerment. We tested these assumptions with two studies (one cross-sectional and one time lagged) on diverse samples of employees from different organizations. The first study employed emotional exhaustion as the outcome measure; the second used depression. Results from both studies support the proposed process by showing that LMX positively affects empowerment, which negatively affects emotional exhaustion (Study 1) and depression (Study 2). Additionally, Study 2 also showed that Team–Member Exchange is as important as LMX for preventing psychological health issues among employees. KW - Depression KW - Mental Health Y1 - 2015 N1 - Online: https://www.researchgate.net/publication/283507876_Good_relationships_at_work_The_effects_of_Leader-Member_Exchange_and_Team-Member_Exchange_on_psychological_empowerment_emotional_exhaustion_and_depression VL - 37 IS - 5 SP - 673 EP - 691 PB - Wiley CY - Hoboken, NJ ER - TY - JOUR A1 - Prieto-González, Lisardo A1 - Jaedicke, Corvin A1 - Schubert, Johannes A1 - Stantchev, Vladimir T1 - Fog computing architectures for healthcare: Wireless performance and semantic opportunities JF - Journal of Information, Communication and Ethics in Society N2 - Purpose – The purpose of this study is to analyze how embedding of self-powered wireless sensors into cloud computing further enables such a system to become a sustainable part of work environment. Design/methodology/approach – This is exemplified by an application scenario in healthcare that was developed in the context of the OpSIT project in Germany. A clearly outlined three-layer architecture, in the sense of Internet of Things, is presented. It provides the basis for integrating a broad range of sensors into smart healthcare infrastructure. More specifically, by making use of short-range communication sensors (sensing layer), gateways which implement data transmission and low-level computation (fog layer) and cloud computing for processing the data (application layer). Findings – A technical in-depth analysis of the first two layers of the infrastructure is given to provereliability and to determine the communication quality and availability in real-world scenarios. Furthermore, two example use-cases that directly apply to a healthcare environment are examined,concluding with the feasibility of the presented approach. Practical implications – Finally, the next research steps, oriented towards the semantic tagging and classification of data received from sensors, and the usage of advanced artificial intelligence-based algorithms on this information to produce useful knowledge, are described together with the derived social benefits. Originality/value – The work presents an innovative, extensible and scalable system, proven to be useful in healthcare environments. KW - Healthcare KW - Cloud computing KW - Ontologies Y1 - 2016 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Full text due to copyright no available. VL - 14 IS - 4 SP - 334 EP - 349 PB - Emerald CY - Bingley ER - TY - JOUR A1 - Leibfried, Stephan A1 - Stecker, Christina T1 - Sozialpolitik: Bilanz und Perspektiven für Forschung und Lehre an den deutschen Universitäten. Eine Einführung an den deutschen Universitäten. Eine Einführ JF - Deutsche Rentenversicherung N2 - Keine Angabe - No details KW - Ausbildungssystem KW - Deutschland KW - Bildung Y1 - N1 - Volltext ist aus urheberrechtlichen Gründen nicht verfügbar. Full text due to copyright not available. VL - 72 IS - 2 SP - 121 EP - 134 ER - TY - JOUR A1 - Kreft, Johanna A1 - Kühling-Thees, Carla A1 - Gockel, Christine T1 - With a little help from my trainers : Ausbildung von Studierenden zu Bewerbungstrainern für Geflüchtete JF - Gruppe. Interaktion. Organisation. Zeitschrift für Angewandte Organisationspsychologie (GIO) N2 - In diesem Beitrag wird über die Ausbildung von Studierenden zu Bewerbungstrainern für Geflüchtete in einem Train-the-Trainer Programm berichtet. Dieses Programm gliedert sich in zwei Phasen. In der ersten Phase erhalten Masterstudierende eine Trainerausbildung und in der zweiten Phase geben die Studierenden selbstständig rekrutierten Geflüchteten Bewerbungstrainings. Mit diesem didaktischen Ansatz können aufgrund des Multiplikatoreneffektes viele Geflüchtete erreicht werden. Um die Effektivität der ersten Phase des Programms für die Studierenden zu überprüfen, wurde eine Fragebogen- und Interviewstudie durchgeführt. Die Ergebnisse zeigten Folgendes: Die Teilnehmenden waren in der Vergangenheit mehr von ihren Familien ermutigt worden, sich für andere einzusetzen als die Teilnehmenden einer Kontrollgruppe. Des Weiteren wiesen sie eine höhere Motivation auf, sich bewusst und aktiv ehrenamtlich zu engagieren. Außerdem verbesserten sich die notwendigen Kernkompetenzen für das Trainieren. Darüber hinaus konnte die Intention, sich ehrenamtlich zu engagieren, sowie die Einstellung zur Arbeitsmarktintegration von Geflüchteten vorhergesagt werden. Wir diskutieren abschließend die Herausforderungen bei der Umsetzung des Projektes. _________________________________________________________ We report on the training of graduate students as job application trainers within a train-the-trainer program. This program consists of two phases: in the first phase of the program, graduate students are trained to become job application trainers and in the second phase, the students give trainings to refugees whom they recruit themselves. Given the multiplier effect of this didactic approach, many refugees may be reached. To evaluate the effectiveness of the first phase of the program for the students, we conducted a questionnaire and interview study. Results of the evaluation show the following: based on their past experience, the participants of the program were more likely to be encouraged by their families to help others than the participants in a control group. In addition, they were more motivated to volunteer deliberately and actively. Furthermore, all necessary core competencies for training performance improved over time. We were also able to predict participants’ intentions to volunteer and their attitude towards labor market integration of refugees. We discuss challenges of the program’s implementation. KW - Train-the-Trainer KW - Geflüchtete KW - Bewerbungstrainings KW - Refugees KW - Job application trainings Y1 - N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Full text due to copyright not available. VL - 48 IS - 3 SP - 217 EP - 223 ER - TY - JOUR A1 - Gerlach, Rebecca A1 - Gockel, Christine T1 - We belong together : belonging to the principal’s in-group protects teachers from the negative effects of task conflict on psychological safety JF - School Leadership & Management N2 - Psychological safety is the shared belief that the team is safe for interpersonal risk-taking. Critical team events such as conflict and faultlines (hypothetical lines that split a team into subgroups) should impact psychological safety. Previous research has shown the benefits of task conflict on team outcomes under certain conditions and the consistently negative effects of demographic faultline strength on team outcomes. We propose that being close to the principal (what we call belonging to the principal’s in-group) should help attenuate the negative effects of task conflict and faultlines among teachers, because it is associated with a more effective working relationship. In a survey study with 244 teachers from 45 primary schools, we tested the moderating effect of belonging to the principal’s in-group vs. belonging to an out-group on the relationships of task conflict and faultlines on psychological safety. Results of multilevel model tests showed that relationship conflict (but not task conflict) and faultlines decreased psychological safety. However, when teachers belonged to the principal’s in-group as compared to an out-group, task conflict had no negative effect on psychological safety. We present implications to bridge the negative effects due to subgroup presence, so that psychological safety can become a resource for all. KW - Psychological safety KW - Task conflict KW - Relationship conflict Y1 - N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Full text due to copyright not available. SP - 1 EP - 21 ER - TY - JOUR A1 - Hessel, Franz T1 - Budget impact of computer-based psychotherapy in Germany JF - Value in Health N2 - Keine Angabe No details KW - Health care Y1 - N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Full text due to copyright not available. ER - TY - JOUR A1 - López González, Lisbet Mailin A1 - Pereda Reyes, Illeana A1 - Romero, Osvaldo T1 - Anaerobic co-digestion of sugarcane press mud with vinasse on methane yield JF - Waste Management N2 - The conversion efficiency of high solids waste digestion as sugarcane press mud (P) may be limited due to hydrolysis step. The option of co-digestion with vinasse, main liquid waste generated from ethanol production, was investigated under batch regime at mesophilic conditions (37.5 ± 1 °C) and the best mixture was evaluated under semicontinuous regime in stirred-tank reactors. The maximum values for methane yield in batch tests were for V75/P25 and V50/P50 mixtures (on basis of the chemical oxygen demand (COD) percentage added in the mixture), with an average value of 246 N mL CH4 g−1 CODfed, which was 13% higher than that of press mud alone. A highest methane production rate of 69.6 N mL CH4 g−1 CODfed−1 d−1 was obtained for the mixtureV75/P25. During the experiment carried out in CSTR reactors, the organic loading rate (OLR) was increased from 0.5 up to 2.2 g VS L−1 d−1. Methane yields of 365 L CH4 kg−1 VS and biogas productivities of 1.6 L L−1 were obtained in co-digestion, which was 64% higher in comparison to mono-digestion. The performance of the process in mono-digestion was less stable than in co-digestion, with a significant fall of methane yield to 1.8 kg VS m−3 d−1, and a partial inhibition of the methanogenic archaeas when the OLR was increased up to 2.2 kg VS m−3 d−1. The co-digestion of vinasse with press mud is a good option for the treatment of streams at the alcohol-sugar industry. KW - Press mud KW - Filter cake KW - Vinasse Y1 - 2017 N1 - Online: https://www.researchgate.net/publication/318540325_Anaerobic_co-digestion_of_sugarcane_press_mud_with_vinasse_on_methane_yield VL - 68 SP - 139 EP - 145 PB - Elsvier ER - TY - JOUR A1 - Jiménez, Janet A1 - Barrera, Ernesto L. A1 - de Vrieze, Jo A1 - Boon, Nico A1 - DeMeester, Steven A1 - Spanjers, Henri A1 - Romero, Osvaldo A1 - Dewulf, Jo T1 - Microbial community dynamics reflect reactor stability during the anaerobic digestion of a very high strength and sulfate‐rich vinasse JF - Journal of Chemical Technology & Biotechnology N2 - BACKGROUND Microbial community dynamics during the anaerobic digestion of vinasse has been little studied. However, having knowledge about it is essential for early detection of reactor operational difficulties to apply preventive actions. This research studies the microbial community dynamics in the anaerobic digestion of vinasse, linking to experimental observations about product yields and organic matter degradation. RESULTS Methane and sulfide yields decreased with increasing SO42‐/COD ratio, while the fraction of organic matter degraded by sulfate reducing bacteria increased from 4.5 ± 0.3% to 27.1 ± 0.6%. The archaeal community showed that acetoclastic Methanosaetaceae were little affected by the increase of the SO42‐/COD ratio, in contrast to the Methanomicrobiales and Methanobacteriales population, which decreased during the experiment. The total bacterial diversity was influenced mainly by substrate composition, showing that the increase of the SO42‐/COD ratio above 0.10 shifted the bacterial community to a lower richness. CONCLUSION These results provide knowledge on the dynamics of the microbial communities, which can be useful to control the anaerobic digestion of sulfate‐rich vinasses, showing that reactor stability equates to the higher ratios between total methanogens and total bacteria gene copy numbers, whereas operational difficulties can be associated to lower bacterial richness and higher community organization. KW - Biotechnology KW - Anaerobic digestion KW - Methanomicrobiales Y1 - 2017 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Full text due to copyright not available. VL - 993 IS - 4 SP - 975 EP - 984 ER - TY - CHAP A1 - López Gonzélez, L. M. A1 - Reyes, I. P. A1 - Romero, Osvaldo T1 - Efecto de la mezcla cachaza-vinaza en el rendimiento de metano y la estabilidad del proceso de dogestión anaerobia N2 - Keine Angabe No details KW - Digestion KW - Sugar Y1 - N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Full text due to copyright not available. ER - TY - CHAP A1 - Britze, Nils A1 - Büsch, Victoria A1 - Hessel, Franz A1 - Stähler, Tobias A1 - Ternès, Anabel T1 - Die steigende Bedeutung des betrieblichen Demografie- und Gesundheitsmanagements im 21. Jahrhundert T2 - Herausforderung Management N2 - Keine Angabe No details KW - Entwicklung KW - Krankheitslast Y1 - 2016 N1 - Buch verfügbar in der Bibliothek der SRH Berlin School of Management and Technology, Signatur AL24000 3. Book available in the library of the SRH Berlin School of Management and Technology, shelf mark AL24000 3. VL - 2016 SP - 62 EP - 79 PB - SRH Hochschule Heidelberg CY - Heidelberg ER - TY - CHAP A1 - Büsch, Victoria A1 - Hessel, Franz A1 - Stähler, Tobias A1 - Ternès, Anabel T1 - Arbeitsfähigkeit von Mitarbeitern stärken - Good-Practice-Beispiele BT - Ansätze aus Forschung und Praxis T2 - Trends im Betrieblichen Gesundheitsmanagement N2 - Obwohl die Diskussion zur Arbeitsfähigkeit der Belegschaft bereits durch Trends wie den demografischen Wandel angeregt wurde, sind entsprechende unternehmerische oder politische Umsetzungen noch selten. Um ein ganzheitliches Betriebliches Gesundheitsmanagement umzusetzen, fehlt es häufig an praxistauglichen Modellen und Anregungen. Dieses Kapitel stellt zunächst Ilmarinens Work-Ability-Modell bzw. das empirische Werkzeug des Work-Ability-Index als mögliche Ansatzpunkte für ein Betriebliches Gesundheitsmanagement vor und zeigt weiterhin Praxisbeispiele auf, die sich mit den Dimensionen bzw. Zielbereichen des Modells assoziieren lassen. KW - Gesundheitsförderung KW - Unternehmen Y1 - 2016 N1 - Buch verfügbar in der Bibliothek der SRH Berlin School of Management and Technology, Signatur QP420 3. Book available in the library of the SRH Berlin School of Management and Technology, shelf mark QP420 3. VL - 2016 SP - 225 EP - 236 PB - Springer CY - Berlin ER - TY - GEN A1 - Hessel, Franz T1 - Vergütung personalisierter Medizin N2 - Keine Angabe No details KW - Personalisierte Medizin KW - Vergütung Y1 - 2012 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. ER - TY - GEN A1 - Hessel, Franz T1 - Gesundheitsökonomische Betrachtung kongenitaler Cytomegalie-Virus Infektionen N2 - Keine Angabe No details KW - Gesundheitsökonomie KW - Cytomegalie-Virus Infektion Y1 - 2012 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. ER - TY - GEN A1 - Hessel, Franz T1 - Gesundheitsökonomische Evaluation nicht nur für Arzneimittel: Diagnostika und Medizinprodukte N2 - Keine Angaben No details KW - Gesundheitsökonomie Y1 - 2012 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. ER - TY - GEN A1 - Hessel, Franz T1 - Gesundheitsökonomische Studien auf der Basis von Registerdaten N2 - Keine Angaben No details KW - Gesundheitsökonomie KW - Registerdaten Y1 - 2012 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. ER - TY - GEN A1 - Hessel, Franz T1 - Qualität der Versorgung von Substitutionspatienten anhand der Premos-Studie N2 - Keine Angabe No details KW - Premos-Studie Y1 - 2012 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. ER - TY - GEN A1 - Hessel, Franz T1 - Auswirkungen des demografischen Wandels auf die Arbeitssituation von Ärzten und Pflegekräften N2 - Keine Angabe No details KW - Demografischer Wandel KW - Medical Recruiting Y1 - 2012 N1 - Volltext aus urheberrechtlichen Gründen nicht verfügbar. Fulltext due to copyright not available. ER -