TY - JOUR A1 - Kirsch, R. A1 - Bergmann, A. A1 - Koller, D. A1 - Leidl, R. A1 - Mansmann, U. A1 - Müller, Martin A1 - Sanftenberg, L. A1 - Schelling, J. A1 - Sundmacher, L. A1 - Voigt, Karen A1 - Grill, E. T1 - Patient trajectories and their impact on mobility, social participation and quality of life in patients with vertigo/dizziness/balance disorders and osteoarthritis (MobilE-TRA): study protocol of an observational, practice-based cohort study JF - BMJ Open N2 - Introduction Mobility limitations have a multitude of different negative consequences on elderly patients including decreasing opportunities for social participation, increasing the risk for morbidity and mortality. However, current healthcare has several shortcomings regarding mobility sustainment of older adults, namely a narrow focus on the underlying pathology, fragmentation of care across services and health professions and deficiencies in personalising care based on patients’ needs and experiences. A tailored healthcare strategy targeted at mobility of older adults is still missing. Objective The objective is to develop multiprofessional care pathways targeted at mobility sustainment and social participation in patients with vertigo/dizziness/balance disorders (VDB) and osteoarthritis (OA) . Methods Data regarding quality of life, mobility limitation, pain, stiffness and physical function is collected in a longitudinal observational study between 2017 and 2019. General practitioners (GPs) recruit their patients with VDB or OA. Patients who visited their GP in the last quarter will be identified in the practice software based on VDB and OA-related International Classification of Diseases 10th Revision. Study material will be sent from the practice to patients by mail. Six months and 12 months after baseline, all patients will receive a mail directly from the study team containing the follow-up questionnaire. GPs fill out questionnaires regarding patient diagnostics, therapy and referrals. Ethics and dissemination The study was approved by the ethical committee of the Ludwig-Maximilians-Universität München and of the Technische Universität Dresden. Results will be published in scientific, peer-reviewed journals and at national and international conferences. Results will be disseminated via newsletters, the project website and a regional conference for representatives of local and national authorities. KW - Vertigo KW - Dizziness KW - Balance Disorders KW - Osteoarthritis KW - Cohort Study Y1 - 2018 UR - http://dx.doi.org/10.1136/bmjopen-2018-022970 VL - 8 IS - 4 SP - e022970 ER - TY - JOUR A1 - Hammerschmidt, Thomas A1 - Zeitler, HP. A1 - Gulich, M. A1 - Leidl, R. T1 - A Comparison of Different Strategies to Collect Standard Gamble Utilities JF - Medical Decision Making N2 - Objective. The authors performed a methodological comparison of the usual standard gamble with methods that could also be used in mailed questionnaires.Methods.Ninety-two diabetic patients valued diabetes-related health states twice. In face-to-face interviews, the authors used an iterative standard gamble (ISG) in which the probabilities were varied in a ping-pong manner and a self-completion method (SC) with top-down titration as search procedure (SC-TD) in 2 independent subsamples of 46 patients. Three months later, all patients received a mailed questionnaire in which the authors used the self-completion method with bottom-up (SCBU) and SC-TD as search procedures.Results.ISG and SCTD showed feasibility and consistency in the interviews. The ISG resulted in significantly higher utilities than the SC-TD. Two thirds of the mailed questionnaires provided useful results indicating some problems of feasibility. Utilities measured by SC-BU and SC-TD did not differ significantly showing procedural invariance. Further, patients indicated ambivalence when given the choice not to definitely state their preferences.Conclusions.The results show that different strategies to collect standard gamble utilities can yield different results. Compared with the usually applied ISG, the SC method is feasible in interviews and provides a consistent alternative that is less costly when used in mailed questionnaires, although its practicability has to be improved in this later setting. KW - utility assessment KW - standard gamble KW - methodology KW - diabetes Y1 - 2018 ER - TY - JOUR A1 - Hammerschmidt, Thomas A1 - Zeitler, HP A1 - Leidl, R. T1 - A utility-theoretic approach to the aggregation of willingness to pay measured in decomposed scenarios: development and empirical test. JF - Health Econ N2 - For cost–benefit analysis, health technologies with multiple effects should be valued in a single scenario by a holistic willingness‐to‐pay (WTP) measure. Recent studies instead used decomposed scenarios in which respondents report their WTP for each individual effect. Evidence can be found that the sum of such decomposed WTPs overestimates the holistic WTP, i.e. the holistic WTP is sub‐additive. This sum of decomposed WTPs can lead to wrong conclusions on the efficiency of health technologies. This is also relevant in decision making about new technologies that are valued separately in different surveys. To date, no utility‐theoretical and empirically validated aggregation function for decomposed WTPs exists. Within an expected utility model, this paper identifies as a reason for sub‐additivity – beside risk aversion with respect to wealth – a negative influence of better health on the marginal utility of wealth, i.e. marginal utility of wealth is smaller in better health states. Assuming mutual utility independence of health and wealth, a theoretically founded aggregation function covering these two impacts is derived. In a contingent valuation study, 92 patients with diabetes were asked to state their WTP for reductions of the risk of several diabetic complications in decomposed as well as in holistic scenarios. The patients had preferences with a significant negative influence of health on the marginal utility of wealth. Sub‐additivity occurred and theoretically founded aggregation could considerably lower the degree of overestimation. These results suggest that the theoretically founded aggregation function might reduce problems of sub‐additivity that can be economically relevant. Further empirical testing of the approach is indicated. KW - holistic willingness‐to‐pay (WTP) KW - economical research Y1 - 2018 ER - TY - JOUR A1 - Hammerschmidt, Thomas A1 - Zeitler, H. P. A1 - Leidl, R. T1 - Unexpected yes- and no-answering behaviour in the discrete choice approach to elicit willingness to pay: a methodological comparison with payment cards JF - International Journal of Health Care Finance and Economics KW - Discrete choice approach KW - Willingness to pay KW - Payment cards Y1 - 2003 IS - 3 / 3 SP - 147 EP - 166 ER - TY - JOUR A1 - Müller, A. A1 - Stratmann- Schöne, D. A1 - Hammerschmidt (ehem. Klose), Thomas A1 - Leidl, R. T1 - Overview of economic evaluation of positron-emission-tomography JF - The European Journal of Health Economics KW - Economic evaluation KW - Positron-emission-tomography Y1 - 2002 IS - 3 / 1 SP - 59 EP - 65 ER - TY - RPRT A1 - Müller, A. A1 - Stratmann- Schöne, D. A1 - Hammerschmidt (ehem. Klose), Thomas A1 - Leidl, R. T1 - Ökonomische Evaluation der Positronen-Emissions-Tomographie BT - Ein gesundheitsökonomischer HTA-Bericht KW - Ökonomische Evaluation KW - Positronen-Emissions-Tomographie KW - HTA- Bericht Y1 - 2001 ER - TY - JOUR A1 - Müller, A. A1 - Stratmann- Schöne, D. A1 - Hammerschmidt (ehem. Klose), Thomas A1 - Leidl, R. T1 - Eine Übersicht über die ökonomische Evaluation der Positronen-Emissions-Tomographie JF - Bundesgesundheitsblatt KW - Ökonomische Evaluation KW - Positronen-Emissions-Tomographie Y1 - 2001 IS - 44 / 9 SP - 895 EP - 902 ER - TY - JOUR A1 - Rösch, M. A1 - Hammerschmidt (ehem. Klose), Thomas A1 - Leidl, R. A1 - Gebhard, F. A1 - Kinzl, L. A1 - Ebinger, T. T1 - Kostenanalyse der Behandlung polytraumatisierter Patienten JF - Der Unfallchirurg KW - Polytraumata KW - Kostenanalyse Y1 - 2000 IS - 8 ER - TY - JOUR A1 - Hammerschmidt (ehem. Klose), Thomas A1 - Leidl, R. A1 - Buchmann, I. A1 - Brams, HJ A1 - Reske, SN T1 - Primary staging of lymphomas: cost-effectiveness of FDG-PET versus computed tomography JF - European Journal of Nuclear Medicine KW - Lymphomas KW - FDG-PET KW - Computer tomography Y1 - 2000 IS - 27 / 10 SP - 1457 EP - 1464 ER - TY - CHAP A1 - Leidl, R. A1 - Hammerschmidt (ehem. Klose), Thomas A1 - Stratmann, D. ED - Rüdel, Reinhardt ED - Stadelhofer, Carmen T1 - Altern, Gesundheitsversorgung und nachhaltige Finanzierbarkeit T2 - Interdisziplinäre Beiträge zur Nachhaltigkeit von Lebensstilen und zu neunen Biotechnologien KW - Gesundheitsversorgung KW - Finanzierung im Gesundheitswesen Y1 - 1999 PB - Kleine Verlag CY - Ulm ER - TY - JOUR A1 - Hammerschmidt (ehem. Klose), Thomas A1 - Herlemann, B. A1 - Leidl, R. T1 - Kostenmessung in der ökonomischen Evaluation von Gesundheitsleistungen: die Kosten stationärer Akutversorgung am Universitätsklinikum Ulm JF - Journal of Public Health / Zeitschrift für Gesundheitswissenschaften KW - Ökonomische Evaluation KW - stationäre Akutversorgung KW - Kosten in der Universitätsklinik Y1 - 1999 IS - 4 ER -