@article{Petković2022, author = {Petković, Dušan}, title = {Specification of Row Pattern Recognition in the SQL Standard and its Implementations}, series = {Datenbank-Spektrum}, volume = {22}, journal = {Datenbank-Spektrum}, number = {2}, doi = {10.1007/s13222-022-00404-3}, pages = {163 -- 174}, year = {2022}, abstract = {Recently, the SQL standardization Committee published a specification for support of the concept called Row Pattern Recognition in SQL. That way, the focus for the members of the Committee turned back to a kernel issue of the language, after standardizing the storage and manipulation of data formats, such as XML and JSON. In this paper we discuss the specified features using several examples and show to what extent different relational database systems as well as Data Analytics tools have integrated them. At the end of the paper, we describe the main inaccuracies of the proposal and the ways how to solve them. From our point of view, the following should be modified in one of the future proposals of the standard in relation to this concept: (a) Naming of several pattern navigation operations is inappropriate and should be changed; (b) The concept of implicit definition for row pattern variables in DEFINE should be changed to explicit; (c) The set of existing functions should be extended.}, language = {en} } @inproceedings{LindnerOrtler2022, author = {Lindner, Johannes A. and Ortler, Matthias}, title = {Zur dynamischen Mischtechnik f{\"u}r die {\"A}nderung des Str{\"o}mungsbilds w{\"a}hrend des Prozessverlaufs}, series = {Jahrestreffen der ProcessNet-Fachgruppen Computational Fluid Dynamics + Mischvorg{\"a}nge + Agglomerations- und Sch{\"u}ttguttechnik}, booktitle = {Jahrestreffen der ProcessNet-Fachgruppen Computational Fluid Dynamics + Mischvorg{\"a}nge + Agglomerations- und Sch{\"u}ttguttechnik}, editor = {Dechema,}, year = {2022}, language = {en} } @misc{BergerBahl2022, author = {Berger, Yvonne and Bahl, Eva}, title = {"Processes of South-South migration in their historical context: Case studies from Brazil and China". Doing Global Sociology in Polarized Worlds: Methodological Approaches from Qualitative Social Research. 41st Congress of the German Sociological Association, Bielefeld, Germany}, editor = {Berger, Yvonne and Bahl, Eva}, year = {2022}, language = {en} } @misc{Berger2022, author = {Berger, Yvonne}, title = {Negotiating Ambiguities - Translation and its Challenges in Qualitative Research, 18th International Congress of Qualitative Inquiry, Champaign-Urbana, USA}, editor = {Berger, Yvonne}, year = {2022}, language = {en} } @inproceedings{KellnerSchroeder2022, author = {Kellner, Florian and Schr{\"o}der, Nadine}, title = {Location Planning \& Analysis Using Uncertain Data}, series = {2021 International Conference on Decision Aid Sciences and Application (DASA)}, booktitle = {2021 International Conference on Decision Aid Sciences and Application (DASA)}, doi = {10.1109/DASA53625.2021.9682323}, pages = {720 -- 723}, year = {2022}, abstract = {In today's big data era, a humongous amount of data are collected from various sources. In many cases, these data are incomplete, imprecise, and uncertain. An illustrative example is the OpenStreetMap project, where users all over the world contribute data on a more or less precise and complete level. This research shows whether these data are suited to support management decisions. A real-world example demonstrates the extent to which location decisions of a fast-food restaurant chain can be reproduced using techniques from the field of advanced analytics. The problem deals with classifying potential locations and comparing the predicted locations with the actual ones. The data used for this example are retrieved from the OpenStreetMap project. We find that the OpenStreetMap data are generally suitable for predicting location decisions. However, the choice of the data analytics technique is crucial. In our illustrative example case, boosted trees resulted in the best forecast, thereby outperforming neural networks, classic trees, and logit models.}, language = {en} } @article{Kellner2022, author = {Kellner, Florian}, title = {Generating greenhouse gas cutting incentives when allocating carbon dioxide emissions to shipments in road freight transportation}, series = {OR Spectrum}, volume = {44}, journal = {OR Spectrum}, doi = {10.1007/s00291-022-00675-y}, pages = {833 -- 874}, year = {2022}, abstract = {Road freight transportation accounts for a great share of the anthropogenic greenhouse gas (GHG) emissions. In order to provide a common methodology for carbon accounting related to transport activities, the European Committee for Standardization has published the European Norm EN-16258. Unfortunately, EN-16258 contains gaps and ambiguities and leaves room for interpretation, which makes the comparison of the environmental performance of different logistics networks still difficult and hinders the identification of best practices. This research contributes to the identification of particularly meaningful principles for the allocation of GHG to shipments in road freight transportation by presenting an analytical framework for studying the performance of the EN-16258 allocation schemes with respect to accuracy, fairness, and the GHG minimizing incentive. In doing so, we continue previous studies that analyzed two important aspects of the EN-16258 allocation rules: accuracy and fairness. This study provides further insights into this allocation problem by investigating the incentive power of the different allocation schemes to opt for the GHG minimal way of running a road freight network. First, we complement the list of transport scenarios introduced in prior studies and present two novel scenarios. Second, we carry out a series of numerical experiments to compare the EN-16258 allocation rules with respect to accuracy, fairness, and the GHG minimizing incentive. We find that the results may differ significantly for the two scenarios, suggesting a case-by-case recommendation. This is particularly interesting because the first scenario confirms the results of the prior studies, while the second scenario rather contradicts them.}, language = {en} } @article{KraftKellner2022, author = {Kraft, Sarah Katharina and Kellner, Florian}, title = {Can Blockchain Be a Basis to Ensure Transparency in an Agricultural Supply Chain?}, series = {Sustainability}, volume = {14}, journal = {Sustainability}, number = {13}, doi = {10.3390/su14138044}, pages = {8044}, year = {2022}, abstract = {Many supply chains within developing countries lack transparency and are fraught with fraud, corruption, and a substantial number of intermediaries. For several decades, the cocoa sector has faced multiple social, economic, and environmental challenges, some of which include the issue of child labor and very low incomes for farmers, leading to poor living conditions. Blockchain technology has a high potential to reduce—or completely eradicate—some of these hurdles. In this article, we present a blockchain-based solution based on the open-source framework Hyperledger Fabric for the cocoa supply chain to promote transparency and reduce fraud. In doing so, we explicitly describe how farmers can be directly integrated into the whole blockchain solution considering the limited infrastructure, knowledge, and technologies available to them. Since about 70\% of all cocoa worldwide is produced in West Africa, this case study uses the cocoa sector in Ghana as an example.}, language = {en} } @article{ParzingerHanfstaenglSiggetal.2022, author = {Parzinger, Michael and Hanfstaengl, Lucia and Sigg, Ferdinand and Spindler, Uli and Wellisch, Ulrich and Wirnsberger, Markus}, title = {Comparison of different training data sets from simulation and experimental measurement with artificial users for occupancy detection — Using machine learning methods Random Forest and LASSO}, series = {Building and Environment}, volume = {223}, journal = {Building and Environment}, doi = {10.1016/j.buildenv.2022.109313}, pages = {109313}, year = {2022}, abstract = {The applications for occupancy detection range from controlling building automation and systems, determining heat transfer coefficients and even assessing the risk of infection in rooms. Studies in the literature use various statistical models, physical models and machine learning techniques to detect occupancy. All these methods require data for training the occupancy detection models. However, data generation is time-consuming and expensive. This study demonstrates the feasibility of using simulated learning data. Using three different data sources, we tested the suitability of different methods for generating learning data. We conducted two experiments in two office spaces with a real user and an artificial user, and we generated a third data set using a building simulation model. In addition, this study compares two different machine learning approaches (Random Forest and LASSO) using environmental parameters. Both machine learning approaches could develop models with a sensitivity of at least 83 \% and a specificity of at least 97 \% with both training data sets. This work shows that it is possible to determine the presence in rooms using simulated data. The results compared to measured data were just slightly less accurate, and the added value due to the lower effort was considerable}, language = {en} } @inproceedings{HerzSigruenerWalteretal.2022, author = {Herz, Jonas and Sigr{\"u}ner, Michael and Walter, David and Muscat, Dirk and Str{\"u}bbe, Nicole}, title = {Coextruded Polymeric Bicomponent Fibers for Concrete Reinforcements}, series = {SAMPE Europe Conference Proceedings 2022, Hamburg, 15. - 17. Nov. 2022}, booktitle = {SAMPE Europe Conference Proceedings 2022, Hamburg, 15. - 17. Nov. 2022}, year = {2022}, language = {en} } @article{RuethingHaupertSchmitzetal.2022, author = {R{\"u}thing, Justus and Haupert, Frank and Schmitz, Regine and Sigr{\"u}ner, Michael and Str{\"u}bbe, Nicole}, title = {A new approach for the friction and wear characterisation of polymer fibres under dry, mixed and hydrodynamic sliding}, series = {Tribologie und Schmierungstechnik}, volume = {69}, journal = {Tribologie und Schmierungstechnik}, number = {Sonderausgabe 2}, pages = {18 -- 25}, year = {2022}, abstract = {A new approach for the friction and wear characterisation of polymer fibres under dry, mixed, and hydrodynamic sliding conditions is developed. The production process of the tested polymer fibres is described and an introduction in fibre-reinforced concrete is given. Tribotesting is done on an optimised tribometer capable of measuring the friction and wear behaviour of polymer fibres with diameters of a few 100 µm under lubricated conditions. Three extruded polypropylene macro fibres with varying diameters are characterised under tribological conditions found in an industrial concrete mixing process. It is shown that detailed friction and wear data of polymer fibres can be gathered.}, language = {en} } @inproceedings{ManiyattuGeegyLeiteretal.2022, author = {Maniyattu, Georgekutty Jose and Geegy, Eldho and Leiter, Nina and Wohlschl{\"a}ger, Maximilian and Versen, Martin and Laforsch, Christian}, title = {Development of a neural network to identify plastics using Fluorescence Lifetime Imaging Microscopy}, series = {2022 IEEE Sensors Applications Symposium (SAS)}, booktitle = {2022 IEEE Sensors Applications Symposium (SAS)}, doi = {10.1109/SAS54819.2022.9881372}, pages = {1 -- 6}, year = {2022}, abstract = {Plastics have become a major part of human's daily life. An uncontrolled usage of plastic leads to an accumulation in the environment posing a threat to flora and fauna, if not recycled correctly. The correct sorting and recycling of the most commonly available plastic types and an identification of plastic in the environment are important. Fluorescence lifetime imaging microscopy shows a high potential in sorting and identifying plastic types. A data-based and an image-based classification are investigated using python programming language to demonstrate the potential of a neural network based on fluorescence lifetime images to identify plastic types. The results indicate that the data-based classification has a higher identification accuracy compared to the image-based classification.}, language = {en} } @inproceedings{LeiterWohlschlaegerVersen2022, author = {Leiter, Nina and Wohlschl{\"a}ger, Maximilian and Versen, Martin}, title = {Frequency-domain fluorescence lifetime imaging as method to analyze wood structures}, series = {Conference on Lasers and Electro-Optics}, booktitle = {Conference on Lasers and Electro-Optics}, organization = {Technical Digest Series (Optica Publishing Group, 2022)}, doi = {10.1364/CLEO_AT.2022.JW3A.19}, pages = {JW3A.19}, year = {2022}, abstract = {The analysis of wood structures using FD-FLIM seems promising for the identification of wood at 488 nm, as lignin has a high impact on the fluorescence lifetime.}, language = {en} } @inproceedings{WohlschlaegerVersenLaforsch2022, author = {Wohlschl{\"a}ger, Maximilian and Versen, Martin and Laforsch, Christian}, title = {Investigation of the Impact of CaCO3 Concentrations on the Fluorescence Lifetime of Polypropylene}, series = {Conference on Lasers and Electro-Optics}, booktitle = {Conference on Lasers and Electro-Optics}, organization = {Technical Digest Series (Optica Publishing Group, 2022)}, doi = {10.1364/CLEO_AT.2022.AM2M.2}, pages = {AM2M.2}, year = {2022}, abstract = {The impact of fillers on the fluorescence lifetime of polymers is still unknown. Investigating polypropylene containing different CaCO3 concentrations using FD-FLIM show an exponential increase in fluorescence lifetime proportional to the CaCO3 density in polypropylene.}, language = {en} } @inproceedings{Kellner2022, author = {Kellner, Robert}, title = {Making Effective Videos For (Live) Online Learning Quickly}, series = {Proceedings of the IUPAP International Conference on Physics Education}, booktitle = {Proceedings of the IUPAP International Conference on Physics Education}, address = {Sydney}, isbn = {978-1-74210-532-1}, pages = {109 -- 109}, year = {2022}, abstract = {Abstract for the presentation held at the 2020 International Conference on Physics Edcucation}, language = {en} } @inproceedings{SchelerDaumeSojitraetal.2022, author = {Scheler, M. and Daume, D. and Sojitra, D. and Neumeyer, T. and Steinbach, S. and Beck, T. and Schulze, A. and H{\"u}ttl, B.}, title = {Precise On-Site Power Analysis of Photovoltaic Arrays by Self-Reference Algorithm}, series = {Proceedings of the 8th World Conference on Photovoltaic Energy Conversion}, booktitle = {Proceedings of the 8th World Conference on Photovoltaic Energy Conversion}, pages = {4}, year = {2022}, abstract = {To detect degradation of photovoltaic systems at an early stage, precise performance determinations are essential. Current-voltage measurements on single modules in indoor labs under well-defined conditions are state-of-the-art. However, this method causes a logistical and economic effort. On-site measurements reduce the effort but are prone to error because of poorly determinable test conditions: The detected temperature on the backside of modules as well as the irradiance detected by pyranometer in tilted module plane usually differs from the actual operating conditions. In consequence, the accuracy of measured current-voltage characteristics is poor. A precise on-site power determination is achieved by a self-reference algorithm. Improvements by self-referencing are not achieved by correcting the raw electrical data, but by replacing the measured test conditions (temperature and irradiance) with effective data. These effective values correspond better to the actual module irradiance and temperature values. Furthermore, precise power determination of photovoltaic arrays requires to identify and exclude emporarily deformed current-voltage curves from consideration, as it can arise from non-uniform irradiation within array like shading. In this paper, the application of a digital curve filter is reported and performance determinations by a self-reference algorithm are demonstrated on a photovoltaic array. We review and discuss the measurement concept in terms of its ease of use. … }, language = {en} } @article{GetchellCarradiniCardonetal.2022, author = {Getchell, Kristen M. and Carradini, Stephen and Cardon, Peter W. and Fleischmann, Carolin and Ma, Haibing and Aritz, Jolanta and Stapp, James}, title = {Artificial Intelligence in Business Communication: The Changing Landscape of Research and Teaching}, series = {Business and Professional Communication Quarterly}, volume = {85}, journal = {Business and Professional Communication Quarterly}, number = {1}, doi = {10.1177/23294906221074311}, pages = {7 -- 33}, year = {2022}, abstract = {The rapid, widespread implementation of artificial intelligence technologies in workplaces has implications for business communication. In this article, the authors describe current capabilities, challenges, and concepts related to the adoption and use of artificial intelligence (AI) technologies in business communication. Understanding the abilities and inabilities of AI technologies is critical to using these technologies ethically. The authors offer a proposed research agenda for researchers in business communication concerning topics of implementation, lexicography and grammar, collaboration, design, trust, bias, managerial concerns, tool assessment, and demographics. The authors conclude with some ideas regarding how to teach about AI in the business communication classroom.}, language = {en} } @inproceedings{CardonFleischmannAritzetal.2022, author = {Cardon, Peter and Fleischmann, Carolin and Aritz, Jolanta and Ma, Haibing and Springer, Ann and Springer, Scott}, title = {The Influence of Psychological Safety and Personality on Technology Acceptance of Team-Based Technology in Global Virtual Teams}, series = {Proceedings of the 55th Hawaii International Conference on System Sciences}, booktitle = {Proceedings of the 55th Hawaii International Conference on System Sciences}, year = {2022}, abstract = {Collaboration platforms for teams, such as Slack, are increasingly used in virtual teams. Conventional wisdom suggests attitudes about adopting these types of platforms is primarily driven by their affordances. Our project emerged from the premise that psychological safety and personality traits can also significantly influence attitudes related to technology adoption. This research of roughly 300 global virtual teams showed that psychological safety influences views of collaboration platforms in terms of performance expectancy, effort expectancy, and hedonic motivation. In addition, this research showed that personality traits influence views of collaboration platforms. These findings about psychological safety and personality traits suggest a team-development approach is an integral component of the technology adoption process. Recommendations for future research are provided.}, language = {en} } @article{LogemannAritzCardonetal.2022, author = {Logemann, Minna and Aritz, Jolanta and Cardon, Peter and Swartz, Stephanie and Elhaddaoui, Terri and Getchell, Kristen and Fleischmann, Carolin and Helens-Hart, Rose and Li, Xiaoli and Palmer-Silveira, Juan Carlos and Ruiz-Garrido, Miguel and Springer, Scott and Stapp, James}, title = {Standing strong amid a pandemic: How a global online team project stands up to the public health crisis}, series = {British Journal of Educational Technology}, volume = {53}, journal = {British Journal of Educational Technology}, number = {3}, doi = {10.1111/bjet.13189}, pages = {577 -- 592}, year = {2022}, abstract = {The annual instructional virtual team Project X brings together professors and students from across the globe to engage in client projects. The 2020 project was challenged by the global disruption of the COVID-19 pandemic. This paper draws on a quantitative dataset from a post-project survey among 500 participating students and a qualitative narrative inquiry of personal experiences of the faculty members. The findings reveal how innovative use of a variety of collaboration and communication technologies helped students and their professors in building emotional connection and compassion to support each other in the midst of the crisis, and to accomplish the project despite connectivity disruptions. The results suggest that the role of an instructor changed to a coach and mentor, and technology was used to create a greater sense of inclusion and co-presence in student-faculty interactions. Ultimately, the paper highlights the role of technology to help the participants navigate sudden crisis affecting a global online instructional team project. The adaptive instructional teaching strategies and technologies depicted in this study offer transformative potential for future developments in higher education.}, language = {en} } @article{MuchaRobertBreitschwerdtetal.2022, author = {Mucha, Henrik and Robert, Sebastian and Breitschwerdt, R{\"u}diger and Fellmann, Michael}, title = {Usability of clinical decision support systems}, series = {Zeitschrift f{\"u}r Arbeitswissenschaft}, journal = {Zeitschrift f{\"u}r Arbeitswissenschaft}, doi = {10.1007/s41449-022-00324-8}, year = {2022}, abstract = {Usability is considered a major success factor for current and future decision support systems. Such systems are increasingly used to assist human decision-makers in high-stakes tasks in complex domains such as health care, jurisdiction or finance. Yet, many if not most expert systems—especially in health care—fail to deliver the degree of quality in terms of usability that its expert users are used to from their personal digital consumer products. In this article, we focus on clinical decision support systems (CDSS) as an example for how important a human-centered design approach is when designing complex software in complex contexts. We provide an overview of CDSS classes, discuss the importance of systematically exploring mental models of users, and formulate challenges and opportunities of future design work on CDSS. We further provide a case study from a current research project to illustrate how we used codesign as a practical approach to produce usable software in a real-world context. Practical Relevance: We make a point for usability to be considered a major success factor and non-negotiable characteristic of expert software. With software evolving into virtual coworkers in terms of supporting human decision-making in complex, high-risk domains, the necessity of and demand for systems that are unambiguously understandable and interpretable for their expert users have never been higher. We show that this is a real-world problem with high practical relevance by describing our work in the domain of clinical decision support systems (CDSS) as an example. We introduce the topic and a classification of CDSS. Thus, we highlight a conceptual framework of how to approach complex domains from a technology designer's point of view. We continue by explaining why usability must be regarded as a major goal in software development. We derive challenges and opportunities that may well be transferred to other domains. Finally, be including a real-world example from our own professional work we propose a practical approach towards taking the challenges and exploiting the associated opportunities.}, language = {en} } @inproceedings{WohlschlaegerVersenLaforsch2022, author = {Wohlschl{\"a}ger, Maximilian and Versen, Martin and Laforsch, Christian}, title = {Investigation of the Impact of CaCO3 Concentrations on the Fluorescence Lifetime of Polypropylene}, series = {2022 Conference on Lasers and Electro-Optics (CLEO)}, booktitle = {2022 Conference on Lasers and Electro-Optics (CLEO)}, pages = {1 -- 2}, year = {2022}, abstract = {The impact of fillers on the fluorescence lifetime of polymers is still unknown. Investigating polypropylene containing different CaCO 3 concentrations using FD-FLIM show an exponential increase in fluorescence lifetime proportional to the CaCO 3 density in polypropylene.}, language = {en} } @article{HempelLapaGaumannetal.2022, author = {Hempel, L.C. and Lapa, C. and Gaumann, A. and Veloso de Oliveira, J. and Scheiber, J. and Philipp, P. and Oyarzun, C. and Wesarg, S. and Robert, Sebastian and Hempel, D.}, title = {36P A point mutation replacing cysteine with arginine at position 382 (C382R) in the transmembrane domain of FGFR2 leads to response to FGF2-inhibitor pemigatinib in chemo-refractory intrahepatic cholangiocarcinoma}, series = {Annals of Oncology}, volume = {33}, journal = {Annals of Oncology}, doi = {https://doi.org/10.1016/j.annonc.2022.01.045}, pages = {S17 -- S17}, year = {2022}, abstract = {Background To date, targeted tyrosine kinase inhibitors have been approved for FGFR2 and FGFR3 fusions (pemigatinib and erdafitinib, respectively), but the importance of FGFR2 mutations for transformation activity and as a druggable gene variant with response to different FGFR inhibitors is poorly understood. FGFR2 inhibitors present a mainstay of treatment for locally advanced or metastatic intrahepatic cholangiocellular carcinoma (iCCA). Methods A 74-year-old male was diagnosed with iCCA in liver segments seven and eight with infiltration of the hepatic veins and inferior vena cava revealed a C382R mutation of the intramembrane domain of FGRR2 receptor. We performed an in-silico study to understand the potential mode-of-action of the mutant FGFR2 targets. Based on experimentally determined structures we then used a structure generated by AlphaFold2 as the variation in question is located at a position not determined well in the experiments. This revealed that the C382R mutation is located in the trans-membranal domain at a position crucial for signal transduction, both for activation and inhibition of downstream-signaling. The Molecular Tumor Board decided to start the treatment with 13.5 mg pemigatinib once daily for 14 days, followed by 7 days of free therapy interval resulting in a sustained partial response. The patient continues to be treated of 13.5 mg as described above. Results In our case report, we were able to show that the patient in whom an C382R mutation was detected responded to the therapy with pemigatinib. This shows that real-world scenarios differ from the data of the approval studies, thereby illustrating how complex data on patients with FGFR mutations is. One of the main problems of large approval studies is that the functionality of the respective alterations is often disregarded. Conclusions Our results suggest that respective mutation may be successfully targeted by FGFR-selective tyrosine-kinase inhibitors, demonstrating the importance of the functional characterization of mutations. no conflicts of interest.}, language = {en} } @article{HempelLapaDierksetal.2022, author = {Hempel, Louisa and Lapa, Constantin and Dierks, Alexander and Gaumann, Andreas and Scheiber, Josef and Veloso de Oliveira, Julia and Philipp, Patrick and Oyarzun Laura, Cristina and Wesarg, Stefan and Robert, Sebastian and Hempel, Dirk}, title = {A new promising oncogenic target (p.C382R) for treatment with pemigatinib in patients with cholangiocarcinoma}, series = {Therapeutic Advances in Medical Oncology}, volume = {14}, journal = {Therapeutic Advances in Medical Oncology}, doi = {10.1177/17588359221125096}, year = {2022}, abstract = {Point mutations of the fibroblast growth factor receptor (FGFR)2 receptor in intrahepatic cholangiocarcinoma (iCC) are mainly of unknown functional significance compared to FGFR2 fusions. Pemigatinib, a tyrosine kinase inhibitor, is approved for the treatment of cholangiocarcinoma with FGFR2 fusion/rearrangement. Although it is hypothesized that FGFR2 mutations may cause uncontrolled activation of the signaling pathway, the data for targeted therapies for FGFR2 mutations remain unclear. In vitro analyses demonstrated the importance of the p.C382R mutation for ligand-independent constitutive activation of FGFR2 with transforming potential. The following report describes the clinical case of a patient diagnosed with an iCC carrying a FGFR2 p.C382R point mutation which was detected in liquid, as well as in tissue-based biopsies. The patient was treated with pemigatinib, resulting in a sustained complete functional remission in fluorodeoxyglucose-positron emission tomography/computed tomography over 10 months to date. The reported case is the first description of a complete functional remission under the treatment with pemigatinib in a patient with p.C383R mutation.}, language = {en} } @article{HempelPiehlerGandorferetal.2022, author = {Hempel, Louisa and Piehler, Armin and Gandorfer, Beate and De Oliveira, Julia Veloso and Philipp, Patrick and Robert, Sebastian and Axel, Kleespies and Schick, Cordula and Fleischmann, Bastian and Schweneker, Katrin and Milani, Valeria and Schenk, Kristina and Ebner, Florian and Donhauser, Lara and Zehn, Dietmar and Hempel, Dirk}, title = {Clinical impact of SARS-CoV-2 delta variant infection in tumor patients and the impact of vaccination on different cancer treatment regimens.}, series = {Journal of Clinical Oncology}, volume = {40}, journal = {Journal of Clinical Oncology}, number = {16_suppl}, doi = {10.1200/JCO.2022.40.16_suppl.e18750}, pages = {E18750 -- E18750}, year = {2022}, abstract = {Background: Data on SARS-CoV-2 infections in oncological patients in the outpatient settings are scarce. Methods: During the spread of the delta variant between April 2021 and September 2021, a total of 10.677 patients were tested for SARS-CoV-2 infection by RT-qPCR in seven outpatient clinics in Bavaria, Germany. Results: Within the tested patient cohort, 4.960 patients (46.5\%) suffered from a malignant disease (74\% solid tumors and 26\% malignant hematological diseases). This group was compared with 5.717 patients (53.5\%) without a malignant disease (33.1\% with other hematological diseases and 66.9\% patients without a hematological or oncological disease). During the observation period, 119 (2.4\%) patients with malignancies were tested positive (88 patients with solid tumors; 31 patients with malignant hematological diseases) compared to 115 positive patients (2.0\%) in the control group. 32 of 119 positively tested patients (26.9\%) suffering from malignant disease required hospitalization and 9/32 patients (28.1\%) died during the clinical course. Conclusions: These observations are in clear contrast to data from patients we evaluated during the pre-delta variants period between 15 and 26 April 2020 in the same seven outpatient clinics. In this period, a total of 1.227 patients were tested for SARS-CoV-2 by RT-qPCR. 78/1227 patients (6.3\%) were tested positive in RT-qPCR and most showed mild symptoms of infection. None of the SARS-CoV-2 infected patients died. These data were analyzed when no vaccination was available. These data were evaluated during a period where no vaccine was available. Vaccination of patients with malignancies with BiontechPfizer's mRNA vaccines was started in April 2021. The response to the vaccine was tested by an antibody assay (Elecsys Anti-SARS-CoV-2 S-immunoassay, Roche) at the earliest four weeks after the second vaccination. To assess the response, we compared five patient cohorts: Patients who received (i) B cell depleting antibodies, (ii) checkpoint inhibitors (ICI), (iii) chemotherapy, or (iv) tyrosin kinase inhibitors (TKIs), and (v) healthy controls. The patients treated with ICI or TKI showed a comparable vaccination response to the healthy patients, while patients receiving Rituximab/Obinutuzumab showed no significant humoral vaccination response at all. The more severe disease course of patients infected by the SARS-CoV-2 delta variant compared to the initial waves of infections strongly underline the importance of vaccination in cancer patients.}, language = {en} } @article{LeiterWohlschlaegerVersenetal.2022, author = {Leiter, Nina and Wohlschl{\"a}ger, Maximilian and Versen, Martin and Laforsch, Christian}, title = {An algorithmic method for the identification of wood species and the classification of post-consumer wood using fluorescence lifetime imaging microscopy}, series = {Journal of Sensors and Sensor Systems}, volume = {11}, journal = {Journal of Sensors and Sensor Systems}, number = {1}, doi = {10.5194/jsss-11-129-2022}, pages = {129 -- 136}, year = {2022}, abstract = {In this contribution the frequency domain fluorescence lifetime imaging microscopy (FD-FLIM) technique is evaluated for post-consumer wood sorting. The fluorescence characteristics of several wood samples were determined, whereby two excitation wavelengths (405 and 488 nm) were used. The measured data were processed using algorithmic methods to identify the wood species and post-consumer wood category. With the excitation wavelength of 405 nm, 16 out of 19 samples could be correctly assigned to the corresponding post-consumer wood category by means of the fluorescence lifetimes. Thus, the experimental results revealed the high potential of the FD-FLIM technique for automated post-consumer wood sorting.}, language = {en} } @inproceedings{LeiterWohlschlaegerVersenetal.2022, author = {Leiter, Nina and Wohlschlaeger, Maximilian and Versen, Martin and Laforsch, Christian}, title = {Non-destructive differentiation of treated and non-treated wood using fluorescence lifetime imaging microscopy}, series = {Sensors and Measuring Systems; 21th ITG/GMA-Symposium}, booktitle = {Sensors and Measuring Systems; 21th ITG/GMA-Symposium}, pages = {1 -- 6}, year = {2022}, language = {en} } @inproceedings{WohlschlaegerVersenLaforsch2022, author = {Wohlschlaeger, Maximilian and Versen, Martin and Laforsch, Christian}, title = {A novel approach to optically detect microplastic in an environmental matrix with Rapid-FLIM}, series = {Sensors and Measuring Systems; 21th ITG/GMA-Symposium}, booktitle = {Sensors and Measuring Systems; 21th ITG/GMA-Symposium}, pages = {1 -- 6}, year = {2022}, language = {en} } @inproceedings{LeiterWohlschlaegerVersen2022, author = {Leiter, Nina and Wohlschl{\"a}ger, Maximilian and Versen, Martin}, title = {Frequency-domain fluorescence lifetime imaging as method to analyze wood structures}, series = {2022 Conference on Lasers and Electro-Optics (CLEO)}, booktitle = {2022 Conference on Lasers and Electro-Optics (CLEO)}, pages = {1 -- 2}, year = {2022}, language = {en} } @inproceedings{WohlschlaegerVersenLaforsch2022, author = {Wohlschl{\"a}ger, Maximilian and Versen, Martin and Laforsch, Christian}, title = {Optical identification of car tire particles on soil using fluorescence lifetime imaging microscopy}, series = {Optical Sensors and Sensing Congress 2022 (AIS, LACSEA, Sensors, ES), Technical Digest Series (Optica Publishing Group, 2022)}, booktitle = {Optical Sensors and Sensing Congress 2022 (AIS, LACSEA, Sensors, ES), Technical Digest Series (Optica Publishing Group, 2022)}, doi = {10.1364/ES.2022.ETu3H.3}, pages = {ETu3H.3}, year = {2022}, abstract = {Tire wear is one of the major contributors of environmental pollution by microplastic. FD-FLIM in combination with an image processing algorithm are successfully applied to detect tyre wear on soil.}, language = {en} } @unpublished{KimmerleDvorskyLiessetal.2022, author = {Kimmerle, Sven-Joachim and Dvorsky, Karl and Liess, Hans-Dieter and Avenhaus, Rudolf}, title = {Time to Failure under Varying Thermal Stresses}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:861-opus4-19126}, pages = {30}, year = {2022}, abstract = {Varying thermal stresses influence significantly the time to failure of electric components as used, for instance, in automotive devices. For applications as autonomous driving a high reliability has to be guaranteed. In this article we discuss how to combine probability distributions for failure. Discrete and continuous changes of the probability distribution in time are both considered. It turns out that the temporal order of the distributions, corresponding to the succession of stresses in applications, is essential. The latter observation restricts the general applicability of the widely used temperature collectives where only the total time of a temperature stress is considered neglecting the order of the stresses. An application of our results are thermal overstress tests on electric components. We may explain yet not well understood measurements for automotive electric cables.}, language = {en} } @inproceedings{Seliger2022, author = {Seliger, Norbert}, title = {A Differential Relaxation Oscillator for Inductive Power Transfer}, series = {2022 IEEE Industrial Electronics and Applications Conference (IEACon)}, booktitle = {2022 IEEE Industrial Electronics and Applications Conference (IEACon)}, publisher = {IEEE}, pages = {1 -- 6}, year = {2022}, abstract = {We present a novel differential relaxation oscillator for inductive power transfer. The proposed oscillator offers an automatic adaption of the oscillation period to a change in the power link impedance, which ensures a high efficient operation for variable loads and coupling factors. A detailed circuit model of the self-oscillation system is provided with analytical design equations. We find a large self-oscillation range for variable coupling factors and loads. The theoretical results are confirmed by circuit simulation and measurements carried out on a low-power demonstrator system. We demonstrate non-resonant and robust self-adaption of the relaxation oscillator to coupling factors ranging from k=0.6-0.9.}, language = {en} } @article{KubikKoslowskiSchubertetal.2022, author = {Kubik, Veit and Koslowski, Kenneth and Schubert, Torsten and Aslan, Alp}, title = {Metacognitive judgments can potentiate new learning: The role of covert retrieval}, series = {Metacognition and Learning}, journal = {Metacognition and Learning}, year = {2022}, abstract = {Interim tests of previously studied information can potentiate subsequent learning of new information, in part, because retrieval-based processes help to reduce proactive interference from previously learned information. We hypothesized that an effect similar to this forward testing effect would also occur when making judgments of (prior) learning (JOLs). Previous research showed that making JOLs likely prompts covert retrieval attempts and thereby enhances memory, specifically when providing only parts of previously studied information. This study examined the forward effect of different types of JOLs (i.e., with complete or partial prior study information available) on subsequent learning of new materials, compared to restudy and retrieval practice. In a between-subjects design, participants (N = 161) consecutively studied five lists of 20 words with the aim to recall as many of them on a final cumulative recall test. After the presentation of each of the first four lists, participants either restudied the list, made JOLs with complete words, made JOLs with word stems, or they were tested on word stems. Compared to restudy, practicing retrieval and making JOLs with word stems, but not JOLs with complete words, facilitated the List-5 interim recall performance and attenuated the number of intrusions from prior lists. The findings suggest that, similar to overt retrieval, making JOLs with incomplete information can enhance new learning to the extent that it elicits covert retrieval attempts.}, language = {en} } @inproceedings{Seliger2022, author = {Seliger, Norbert}, title = {Self-Oscillating Capacitive Power Transfer with Multiple Receiver Capability and Coupling Path Adaption}, series = {Proceedings 24th European Conference on Power Electronics and Applications (EPE'22 ECCE Europe)}, booktitle = {Proceedings 24th European Conference on Power Electronics and Applications (EPE'22 ECCE Europe)}, publisher = {EPE}, organization = {Labor f{\"u}r Leistungselektronik und EMV, TH Rosenheim}, pages = {6}, year = {2022}, language = {en} } @inproceedings{SeligerFaltlhauser2022, author = {Seliger, Norbert and Faltlhauser, Georg}, title = {Active Expansion Sampling of Magnetic Near-Fields in Unbounded Regions}, series = {Proceedings 26th IEEE Workshop on Signal and Power Integrity (IEEE SPI-2022)}, booktitle = {Proceedings 26th IEEE Workshop on Signal and Power Integrity (IEEE SPI-2022)}, publisher = {IEEE}, organization = {Labor f{\"u}r Leistungselektronik und EMV, TH Rosenheim}, pages = {4}, year = {2022}, language = {en} } @inproceedings{DechantSeligerKennel2022, author = {Dechant, Eduard and Seliger, Norbert and Kennel, Ralph}, title = {Common Mode DGS EMI Filter Integrated into a GaN Half Bridge Switching Cell}, series = {Procceedings International Exhibition and Conference for Power Electronics, Intelligent Motion, Renewable Energy and Energy Management (PCIM 2022)}, booktitle = {Procceedings International Exhibition and Conference for Power Electronics, Intelligent Motion, Renewable Energy and Energy Management (PCIM 2022)}, publisher = {Mesago}, organization = {Labor f{\"u}r Leistungselektronik und EMV, TH Rosenheim}, pages = {6}, year = {2022}, language = {en} } @inproceedings{SeligerDechantKennel2022, author = {Seliger, Norbert and Dechant, Eduard and Kennel, Ralph}, title = {EMI mitigation by substrate integrated common mode filter}, series = {Proceedings of 12th International Conference on Integrated Power Electronics Systems (CIPS 2022)}, booktitle = {Proceedings of 12th International Conference on Integrated Power Electronics Systems (CIPS 2022)}, publisher = {VDE}, address = {Berlin (Germany)}, organization = {Labor f{\"u}r Leistungselektronik und EMV, TH Rosenheim}, year = {2022}, language = {en} } @article{HummelObermeierZieretal.2022, author = {Hummel, Sabine and Obermeier, Katharina and Zier, Katja and Krommes, Sandra and Schemme, Michael and Karlinger, Peter}, title = {Analysis of Mechanical Properties Related to Fiber Length of Closed-Loop-Recycled Offcuts of a Thermoplastic Fiber Composites (Organo Sheets)}, series = {Materials}, volume = {15}, journal = {Materials}, number = {11}, pages = {3872}, year = {2022}, abstract = {Increasing demand for energy-efficient means of transport has steadily intensified the trend towards lightweight components. Thermoplastic glass fiber composites (organo sheets) play a major role in the production of functional automotive components. Organo sheets are cut, shaped and functionalized by injection molding to produce hybrid components, such as those used in car door modules. The cutting process produces a considerable amount of production waste, which has thus far been thermally recycled. This study develops a closed mechanical recycling process and analyzes the different steps of the process. The offcuts were shredded using two shredding methods and implemented directly in the injection-molding process. Using tensile tests and impact bending tests, the material properties of the recycled materials were compared with the virgin material. In addition, fiber length degradation via the injection-molding process and the influence of the waterjet-cutting process on the mechanical properties are investigated. Recycled offcuts are both comparable to new material in terms of mechanical properties and usability, and are also economically and ecologically advantageous. Recycling polypropylene waste with glass fiber reinforcement in a closed loop is an effective way to reduce industrial waste in a sustainable and economical production process.}, language = {en} } @inproceedings{SchaefleGraupnerStanzel2022, author = {Schaefle, Claudia and Graupner, Franziska and Stanzel, Silke}, title = {TOWARDS A THERMAL CONCEPTUAL ASSESSMENT FOR FIRST-YEAR ENGINEERING STUDENTS - TCA-1Y}, series = {Proceedings of the 11th international conference on Physics Teaching in Engineering Education}, booktitle = {Proceedings of the 11th international conference on Physics Teaching in Engineering Education}, organization = {SEFI - Soci{\´e}t{\´e} Europ{\´e}enne pour la Formation des Ing{\´e}nieurs}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:861-opus4-18637}, pages = {6}, year = {2022}, abstract = {We report from an ongoing process to develop a thermal conceptual assessment that covers the essential concepts of first-year thermodynamics to be administered to engineering students. The goal is to develop a measurement instrument in order to investigate students' pre-knowledge as well as the influence of teaching and learning settings. The assessment builds on known misconceptions and concept questions described in the literature. The original items have been modified significantly in the current version 3 of the test in order to create single-choice questions with four distracters each that address frequent misconceptions from student answers in a systematic way. The working process to create these distracters is described exemplarily.}, language = {en} } @article{ProdingerCoenenHammondetal.2022, author = {Prodinger, Birgit and Coenen, Michaela and Hammond, Alison and K{\"u}{\c{c}}{\"u}kdeveci, Ay{\c{s}}e A. and Tennant, Alan}, title = {Scale Banking for Patient-Reported Outcome Measures That Measure Functioning in Rheumatoid Arthritis: A Daily Activities Metric}, series = {Arthritis Care \& Research}, volume = {74}, journal = {Arthritis Care \& Research}, number = {4}, pages = {579 -- 587}, year = {2022}, abstract = {Objective Functioning is an important outcome for the management of rheumatoid arthritis (RA). Heterogeneity of respective patient-reported outcome measures (PROMs) challenges direct comparisons between their results. This study aimed to standardize reporting of such PROMs measuring functioning in RA to facilitate comparability. Methods Common-item nonequivalent group design with the Health Assessment Questionnaire (HAQ) as a common scale across data sets from various countries (including the UK, Turkey, and Germany) to establish a common metric was used. Other PROMs included are the physical function items of the Multidimensional HAQ (MDHAQ), the Disabilities of the Arm, Shoulder, and Hand questionnaire, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), the World Health Organization Disability Assessment Schedule II (WHODAS II), the Medical Outcomes Study Short Form 36 (SF-36) health survey, and 4 short forms (20, 10, 6, and 4 physical function items) from the Patient-Reported Outcomes Measurement Information System. As the HAQ includes mobility, self-care, and domestic life items, this study focuses on these 3 domains. PROMs were described using standard error of measurement (SEM) and smallest detectable difference (SDD). A Rasch measurement model was used to create the common metric. Results The range of the SEM was 0.2 (MDHAQ) to 7.4 (SF-36 health survey physical functioning domain). The SDD revealed a range from 9.7\% (WOMAC rating scale) to 33.5\% (WHODAS physical functioning domain). PROMs co-calibration revealed fit to the Rasch measurement model. A transformation table was developed to allow exchange between PROM scores. Conclusion Scores between the daily activity PROMs commonly used in RA can now be compared. Factors such as SEM and SDD help to determine the choice of a PROM in clinical practice and research.}, language = {en} } @incollection{Prodinger2022, author = {Prodinger, Birgit}, title = {Institutional Ethnography}, series = {Rehabilitation in Practice}, booktitle = {Rehabilitation in Practice}, editor = {Hayre, Christopher M. and Muller, Dave J. and Hackett, Paul M. W.}, publisher = {Springer}, address = {Singapore}, publisher = {Technische Hochschule Rosenheim}, pages = {55 -- 66}, year = {2022}, abstract = {Rehabilitation aims to enable people with disabilities or who are likely to experience disability to participate fully in their daily lives through a set of interprofessional and multimodal measures. Yet, rehabilitation services are embedded within social and healthcare systems that shape what individuals, who are active within these systems, can and may have to do. This chapter introduces Institutional Ethnography, a critical method of inquiry, which aims to explicate what people actually do and experience and how their doings and experiences become organized within textually mediated social relations. For rehabilitation practice and research, Institutional Ethnography is a powerful method to delineate which concepts are dominating institutional practices and to explicate whether these concepts are comprehensive enough to serve not only institutional purposes but account for and respond to the realities of people's daily lives.}, language = {en} } @inproceedings{HirschmuellerKovrygaUnterbergeretal.2022, author = {Hirschm{\"u}ller, Sebastian and Kovryga, Andriy and Unterberger, Seraphin and Larbig, Harald and Marais, Brendan and Brischke, Christian and van de Kuilen, Jan-Willem and Krey, Adrian}, title = {Laminated veneer lumber made from cement-impregnated veneers}, series = {The 10th European Conference on Wood Modification}, booktitle = {The 10th European Conference on Wood Modification}, editor = {Gerardin, Philippe and Militz, Holger}, pages = {5}, year = {2022}, abstract = {Typically, to improve the fire resistance of wood, chemical substances, including phosphorus, borate, phenols, nitrogen and halogen based compounds, are impregnated into the wooden material. However, due to problems related to the toxic properties of these fire-retardant compounds, new fire-retardancy methods based on a mineralization process have been developed. Cementitious mineralization of wood is a novel and alternative approach for a non-toxic flame retardant, with viable application in laminated veneer lumber. This paper briefly describes the effects of different solid impregnation materials on the thermal properties and fire retardance of beech veneers (Fagus sylvatica L.). Beech veneers were impregnated with a suspension of (i) microfine binder and glycol, (ii) microfine binder mixed with calcium oxalate monohydrate and glycol, and (iii) aluminium hydroxide and glycol, in a vacuum/high pressure process. Single-flame source tests of with different solids impregnated veneers revealed a considerable improvement in flame retardancy of cementitious mineralized beech veneers compared to untreated control specimens.}, language = {en} } @techreport{Hammerschmidt2022, type = {Working Paper}, author = {Hammerschmidt, Thomas}, title = {Sustainability of pharmaceutical expenditures in the German social health care system}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:861-opus4-18523}, pages = {16}, year = {2022}, abstract = {Background Pharmaceutical expenditure grow strongly in most health care systems. Especially high prices of new drugs are perceived to be driver of growth which might threaten the sustainability of financing drugs. Objective The study aims to analyse a) whether German health policies can achieve sustainable growth of pharmaceutical expenditure, and b) which therapeutic groups fasten and slow pharmaceutical growth based on price and/or volume effects. Methods Annual growth rates of pharmaceutical expenditure in the German social health insurance (SHI) between 2006 and 2018 are compared with indicators reflecting the ability to pay. Annual growth rate in therapeutic subgroups are analysed with respects to volume and price developments. Results Without policies to control pharmaceutical spending, annual growth rates are significantly higher than the growths of indicators of ability to pay. After accounting for the savings from health policy measures, net pharmaceutical expenditure does not grow significantly faster than ability to pay. Policies mainly targeting generic drugs achieve threefold savings compared with policies targeting at patent-protected drugs, although the latter account for more than halve of the expenditure. A limited number of therapeutic subgroups with new drugs grow significantly faster than average expenditure, but this growths is counterbalanced by subgroups which in the end of their innovation cycle and a huge proportion of generic drugs. Conclusion The growths of net drug expenditure in the German SHI does not threaten the sustainability of financing health expenditure based on comprehensive policy measures and innovation cycle effects. Generics do contribute savings to a larger extent. Key points for decision makers: • Germany efficiently uses a comprehensive set of health policies to control drug expenditure in the social health insurance with limited impact on reimbursement. • Net drug expenditure grow on annual rates which correlate to ability to pay and thus do not threaten sustainability of health care financing. • Natural progress of innovation cycles together with targeted policies on patent-protected as well as generic drugs counterbalance exaggerated growth in areas with a high degree of innovation. • Policies targeted mainly on generic drugs yield threefold savings compared with policies targeting on patent-protected drugs. This imbalance should be considered in potential refinements of drug policies.}, language = {en} } @article{ObermeierKarlingerSchemmeetal.2022, author = {Obermeier, Frederik and Karlinger, Peter and Schemme, Michael and Altst{\"a}dt, Volker}, title = {Thermoplastic Hybrid Composites with Wood Fibers: Bond Strength of Back-Injected Structures}, series = {Materials}, volume = {15}, journal = {Materials}, number = {7}, pages = {2473}, year = {2022}, abstract = {Due to their lightweight potential and good eco-balance, thermoplastic hybrid composites with natural fiber reinforcement have long been used in the automotive industry. A good alternative to natural fibers is wood fibers, which have similar properties but are also a single-material solution using domestic raw materials. However, there has been hardly any research into wood fibers in thermoplastic back-injected hybrid composites. This article compares the bond strength of an injection molded rib from polypropylene (PP) and wood fibers to different non-wovens. The non-wovens consisted of wood fibers (spruce) or alternatively natural fibers (kenaf, hemp), both with a polypropylene matrix. Pull-off and instrumented puncture impact tests show that, given similar parameters, the natural and wood-fiber-hybrid composites exhibit very similar trends in bond strength. Further tests using viscosity measurements, microscopy, and computed tomography confirm the results. Wood-fiber-reinforced thermoplastic hybrid composites can thus compete with the natural fiber composites in terms of their mechanical behavior and therefore present a good alternative in technical semi-structural applications.}, language = {en} }