Open Access

Ernest Malov

• Hydrogels are a broad field of materials with applications in many niche areas. To advance the state of the art, research should explore new combinations of chemical and practical components to discover syntheses with novel emergent properties. However, given the vast amount of information available, it is challenging to systematically narrow the search to an effective comparison of a few select candidates. This work proposes a selection and evaluation methodology for building a comparative scope to decide on a set of hydrogel recipe components. Recipe design needs are determined using an existing bibliometric analysis of a hydrogel subfield, and available options are sourced from literature reviews, then assessed based on properties discussed in the literature. Candidates for the crosslinking initiation mechanism, the monomer system, and the crosslinking control method are evaluated separately and sequentially. Recipe permutations are possible as multiple choices are scored. The resultant recipe is a photoinitiated (LAP; irradiated at 380.5nm), thiol-ene (TMPMP-Maleimide), light-patterned (maskless PWM-DLP) hydrogel that swells and bends in response to water due to osmolyte (D-Sorbitol) diffusion. This novel formulation is not currently present in the literature; however, it does not exhibit any chemical or practical incompatibilities. A range of component concentrations, possible failure scenarios, and recommended fixes are provided for initial testing.