TY - THES A1 - Hülshoff, Kristina T1 - Visualisierung klimafreundlicher Baumaßnahmen am Beispiel der Stadt Xanten N2 - Due to anthropogenic climate change, cities need to be restructured. New measures are necessary to achieve climate neutral cities. With the assistance of 3D Programs, concepts against flooding, heat and in favor of mobility transition can be visualized. This thesis will emphasize why it is so relevant to take actions against climate change and will investigate which measures are helpful, especially in cities. In connection, the ideation of measures for the City of Xanten will be presented. Subsequently, the process of chosen Design Style and concepts for various Xanten locations will be explained and displayed. These elaborated concepts can be seen as a thought provoking impulse for at least Xanten, which may be realized in the future. KW - 3D Visualisierung KW - Klimawandel KW - Stadtplanung KW - Xanten Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18847 ER - TY - THES A1 - Cremer, Luca T1 - Opportunity and Risk. A critical Assessment of the Ethics of Artificial Intelligence N2 - The literature review at hand addresses the following research question: “Does artificial intelligence and its future development potentially pose a significant threat to individuals’ well-being and humanity’s ethical values?”. For providing answers to the topic at hand, three hypotheses are investigated in detail out of which H0: “Artificial intelligence does pose a significant potential threat to individuals well-being and humanity’s ethical values.” is accepted in accordance with evaluation of findings gathered from 121 sources overall. Threats of artificial intelligence were identified in overall five fields of application, namely medical science, transport industry, potential militarization, surveillance as well as in interaction of artificial intelligence with consumers, for which the natural language processing model ChatGPT was investigated. Regarding medical sciences, threats include potential dehumanization effects through care robots equipped with artificial intelligence. In the transport industry, multiple issues may arise with autonomously operating vehicles while in potential military application of artificial intelligence, research is conducted in multiple countries. Regarding surveillance, artificial intelligence severely facilitates the implementation of social credit systems, as for instance seen in China. Additionally, human nature is embedded in the context of continuous development of artificial intelligence with aim of establishing a first approximation to guidelines of potentially needed limitations of further development of artificial intelligence. It is concluded that, for implementing specific limitations on development of artificial intelligence, more research is needed for identifying the most suitable approach of limiting further development of artificial intelligence. KW - Artificial intelligence KW - Human nature KW - Ethics KW - Threats of artificial intelligence Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18656 ER - TY - THES A1 - Üngüder, Ömer Özgün T1 - Real-Time Chat Application with ADALM-PLUTO Software Defined Radio N2 - Software-defined radios (SDRs) are flexible, inexpensive, portable, and efficient devices that can be used in the development of applications and solutions for various domains, from telecommunications to radar systems. In this thesis, I present the PlutoChat application that establishes wireless digital communication between two AdalmPluto SDRs in Python programming language. To take advantage of the structure of the Pluto SDR RF chip and handle phase shifts, I introduce the 4/2-QAM quadrature amplitude modulation. For the PlutoChat application, I developed the communication system's components, both on the transmitting and receiving ends, in Python and tested with the data obtained from the Pluto SDR. To address the challenges related to carrier recovery and timing synchronization, adaptive algorithms were used in PlutoChat. This thesis also outlines a communication protocol that involves symbol conversion and frame generation to facilitate the transmission of text messages over the air. To ensure system reliability, I measured the local oscillator performance of the Pluto SDR and tested individual communication blocks of the PlutoChat, including both receiver and transmitter components, using an example text through the Pluto SDR. Having achieved successful transmission and reception, I integrated the communication system blocks in the PlutoChat application. To validate the practical utility of PlutoChat, the end users engaged with the system, sending and receiving text messages via the IPython terminal. KW - PlutoChat KW - software-defined radio KW - PlutoSDR KW - chat application KW - SDR Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18525 ER - TY - THES A1 - Lezana Pascual, Miguel T1 - Development of an Agrivoltaic Plant N2 - The present paper deals with developing two Agrivoltaics (Agri-PV) plants in Kleve, Germany, to study their feasibility and analyze the interaction between cattle farming and solar photovoltaic power generation. The study area will be used as pasture to feed the cows, which will allow evaluation of the economic and technical feasibility of this combination in an area called the "test area" and then to perform the second installation with a larger area called the "potential area." The main results include the decisions taken for the plant's design, the efficiency and performance of the Agri-PV system, the economic results obtained through simulations in PV*SOL software, and the use of plans developed in AutoCAD. The objective of the report is the correct implementation of the Agri-PV system in both the test area and the potential area. It has been demonstrated that integrating solar energy in agricultural areas offers a favorable economic projection, with adequate returns and positive cash flows. This implementation represents an opportunity to diversify income in the farm sector by generating energy for export to the power grid. The conclusions highlight the feasibility of the Agri-PV model and its potential as an effective solution for renewable energy generation in agricultural areas. Further research is suggested to evaluate the impact on agricultural productivity and the interaction of the cows with the panels and to conduct long-term economic and financial studies to ensure the system's sustainability. KW - AGRIVOLTAIC KW - DEVELOPMENT KW - AGRI-PV KW - PLANT Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18536 ER - TY - THES A1 - Rohlfing, Pauline T1 - Einfluss von Benzalkoniumchlorid auf die Selektion von Bakteriengemeinschaften und die Verbreitung von Resistenzgenen in mit Mikroplastik angereichertem Boden N2 - Die zunehmende Anreicherung anthropogener Mikroverunreinigungen in der Umwelt hat in jüngster Zeit verstärkte wissenschaftliche Aufmerksamkeit erhalten. Der steigende Eintrag von Mikroplastik in die Umwelt kombiniert mit der Ausbreitung von Resistenzgenen erfordert eine eingehende Analyse ihrer möglichen Interaktionen und Auswirkungen auf die Ökosysteme. In dieser Studie stand die Interaktion zwischen Mikroplastik, speziell HDPE, einem nicht biologisch abbaubaren Polymer, und PHBH, eine biologisch abbaubare Alternative, in Kombination mit Benzalkoniumchlorid im Fokus. Ziel war es, deren Einfluss auf die Gemeinschaftsstruktur von Bodenmikroorganismen und die Prävalenz von Antibiotikaresistenzgenen zu untersuchen. Unter Verwendung eines Mikrokosmos- Designs wurden organisch bewirtschaftete Bodenproben mit den vorgenannten Substanzen über drei und sechs Wochen inkubiert. Im Anschluss wurden die Biofilme auf den Mikropartikeln mittels qPCR und ddPCR analysiert, wobei die Abundanz von Bakterien, Pilzen und dem Klasse-1-Integron-Gen untersucht wurde. Die Ergebnisse können nicht bestätigen, dass Benzalkoniumchlorid die Verbreitung von Resistenzgenen oder mikrobielle Gemeinschaftsstrukturen beeinflusst. Im Gegensatz dazu wirkte PHBH als signifikanter Modulator, der die Vielfalt der Pilz- und Bakterientaxa im Biofilm verringerte, jedoch die Gesamtabundanz erhöhte. Vor dem Hintergrund dieser Befunde werden die potenziellen ökologischen Implikationen der Mikroplastikverschmutzung deutlich. Es betont die Notwendigkeit vertiefter Forschungen, um die komplexen Wechselwirkungen zwischen Mikroplastik und anderen anthropogenen Kontaminanten in terrestrischen Ökosystemen zu verstehen. N2 - The increasing accumulation of anthropogenic micropollutants in the environment has received greater scientific attention in recent years. The rise of microplastics in the environment combined with the spread of resistance genes requires an in-depth analysis of their potential interactions and impacts on ecosystems. This study focused on the interaction between microplastics, specifically HDPE, a non- biodegradable polymer, and PHBH, a biodegradable alternative, in combination with benzalkonium chloride. The aim was to investigate their influence on the community structure of soil microorganisms and the prevalence of antibiotic resistance genes. Using a microcosm design, organically managed soil samples were incubated with the aforementioned substances for three and six weeks. Subsequently, biofilms on the microparticles were analysed using qPCR and ddPCR method, with particular emphasis on the abundance of bacteria, fungi and the class 1 integron gene. The results cannot confirm that benzalkonium chloride influences the dissemination of resistance genes or microbial community structures. In contrast, PHBH acted as a significant modulator, reducing the diversity of fungal and bacterial taxa in the biofilm, but increasing overall abundance. Given these results, the potential ecological implications of microplastic pollution become apparent. It emphasises the need for deeper research to understand the complex interactions between microplastics and other anthropogenic contaminants in terrestrial ecosystems. Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18573 ER - TY - THES A1 - Mumtaz, Muhammad Imran T1 - Generation and expression of a mutated murine tRNA-guanine transglycosylase variant N2 - Translation of messenger RNA carrying the nucleic code for protein synthesis is one of the vital bioprocesses of living organisms. This translation is mediated by transfer RNA, which allocates specific amino acids to the growing chain by decoding the genetic code. The tRNAs with the G34U35N36 anticodon sequence are recognised by an enzyme called tRNA-guanine transglycosylase, which catalyses the exchange of guanine with queuine. TGT enzyme is found in all three domains of life and is involved in post-transcriptional modification. TGT is of keen interest in the development of therapeutics against shigellosis, since the genetic inactivation of TGT leads to decreased pathogenicity in Shigella. For understanding the differences between bacterial and eukaryotic TGT, studies have been performed in the past, which show remarkable resemblance. On the contrary, some pronounced structural contrast can also be observed. One prominent difference is that the bacterial TGT contains a short turn of three amino acids, whereas, in eukaryotes, this turn is replaced by an extended loop of more than 45 amino acids. The function of this loop in eukaryotic TGT is not known. The loop is a highly flexible region and, thus, is not structurally solved. To elucidate the function of this loop, a TGT mutant lacking this loop was generated, expressed and purified. TGT mutant was expressed in different bacterial cell strains. For the purification, different chromatography techniques were utilised. The mutation resulted in a low yield of the protein in comparison to the wild-type TGT. This leads to the inference that the loop influences the physicochemical characteristics of the protein. KW - RNA-guanine transglycosylase KW - Generation KW - Expression KW - Queuine KW - Protein purification KW - Chromatography KW - Site-directed mutagenesis KW - Protein mutation Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18560 ER - TY - THES A1 - Schlüter, Leon T1 - Modelling Power Generation of Photovoltaics using Weather Data for the Design of an Electrolysis System N2 - To simplify the process towards the development of necessary hydrogen energy storage systems, this research project provides important information and tools for the planning process of such systems on a small scale. Several questions about a solar powered system using hydrogen for energy storage designed for the companies WSN and ESN, could not be answered sufficiently with the available tools which made developing new tools necessary. This tool incorporates various input variables and PV energy generation data to simulate the system's performance over a year into a Microsoft Excel based simulation. Within the framework of the tool developed over the course of the thesis, theoretical exploration of various options for system composition can take place. The insights gained there can be transferred to the implementation of actual projects and have an impact on the speed at which these projects can be realized. The results of the simulation led to the proposal of a system designed for the company WSN, where hydrogen serves as a long-term energy storage solution. Notably, this approach significantly reduces the surplus energy that goes unused, making the system more efficient. This research contributes valuable insights and practical tools to enhance the planning and implementation of small-scale hydrogen energy storage projects. KW - System simulation KW - Hydrogen energy storage KW - Green hydrogen KW - Renewable energy storage KW - Renewable microgrid Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18547 ER - TY - THES A1 - Belkhodja, Fatma T1 - Targeted therapy to overcome the blood-brain barrier in treating Glioblastoma N2 - Glioblastoma represents a challenge in oncology, characterized by its aggressive nature and resistance to conventional therapies. This thesis conducts a comprehensive examination of Glioblastoma, with a primary focus on advancing therapeutic strategies through precision medicine and sophisticated drug delivery mechanisms. The inquiry starts with an exhaustive analysis of the intricate blood-brain barrier, a vital neurovascular interface critical for understanding drug delivery complexities to the central nervous system. Subsequently, the study delves into Glioblastoma, elucidating its etiological foundations, molecular intricacies, clinical presentations, and existing treatment paradigms. The core of this research centers on the exploration of state-of-the-art targeted therapies, encompassing molecular-level targeting, immunotherapeutic modalities, and synergistic therapeutic approaches. It dissects a range of strategies aimed at enhancing drug delivery, including chemical disruption techniques, innovative delivery methodologies, and bioengineered approaches. Furthermore, it underscores the transformative potential of nanotechnology, emphasizing nanocarriers as precision tools poised to revolutionize GBM therapy. The literature review is conducted meticulously, drawing from renowned databases like PubMed, NCBI, NIH/National Cancer Institute, JSTOR, and BioMed Central. Additionally, reputable national and international health institute websites, along with carefully selected books from the campus library, contribute to the diverse and robust foundation of credible information. The discussion segment dissects the challenges inherent in GBM targeted treatment, underscores the burgeoning domain of precision medicine, highlights the paradigm-shifting role of theranostics, and outlines a roadmap for future prospects in this intricate landscape. Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18504 ER - TY - JOUR T1 - 34/2023 Neunte Änderungssatzung zur Satzung über die Ausgestaltung des Auswahl- und Zulassungsverfahrens in zulassungsbeschränkten Studiengängen der Hochschule Rhein-Waal vom 07.11.2023 T3 - Amtliche Bekanntmachungen der Hochschule Rhein-Waal - 2023-34 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18428 VL - 2023 IS - 34 ER - TY - THES A1 - Gniffke, Jennifer Eileen T1 - Sole Searching in Germany: Customer Journeys and the Effect of AI Marketing Tools on Footwear Purchases N2 - This thesis examines the effects Artificial Intelligence Marketing has on German customers and their Customer Journey. As Artificial Intelligence is gaining in significance in our lives, it is also starting to make its way into marketing, though it is still in its early stages here. Compared to other countries, like China and the USA, Germany's adaptation of Artificial Intelligence solutions is limited. Current literature shows that the opinions of customers on Artificial Intelligence Marketing in Germany are still rather unexplored. Semi-structured interviews with six young adults from Germany were conducted to investigate their Customer Journey for footwear purchases. Additionally they were introduced to Artificial Intelligence Marketing and their acceptance was analyzed by using the Technology Acceptance Model. The analysis of the results shows that the factor of assistance through Artificial Intelligence Marketing is appreciated by most who do not know what they want before they start their Customer Journey. It is concluded that the actual usage and how this affects German Generation Z customers is dependent on their Customer Journey and how they prefer to shop. KW - Artificial Intelligence KW - Marketing KW - Customer Journey KW - Technology Acceptance Model KW - Germany Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18351 ER - TY - THES A1 - Martin, Alina T1 - Long-term effects after a short learning event: Evaluation of the effectivity of an ESD (Education for Sustainable Development) module on the importance of pollinating insects N2 - In order to design a fairer and more sustainable planet, the United Nations have agreed on the Agenda 2030 and the corresponding 17 sustainable development goals (SDGs) as well as the Education for Sustainable Development (ESD) campaign. In order to assess the effectivity of this widely funded campaign, evaluation is in order. While usually larger projects and programs are evaluated, this thesis focuses on whether a short one-time education event can also create long-term learning effects. For a two-hour module on insect and pollinator diversity and their economic importance and conservation, evaluation was performed using empirical questionnaires with statistical analysis as well as participatory evaluation methodology. Statistical analysis shows that knowledge, skills and motivation increase strongly directly after the event, but for some part lower significantly after three weeks’ time. Participatory interviews reflect very different developments in the participants, with some only having an increased awareness of the topic but others having implemented conservation measures and networking in their daily lives. Overall, the evaluation shows that long-term effects of short events are only partly observable and different depending on the participating person. There is, however, a potential for further education and activism whose importance should not be underestimated. Accordingly, even though longer programs are surely more effective in creating long-term learning effects and activism, short events can be very efficient as a gateway into many sustainability topics and should be part of ESD. KW - ESD KW - BNE KW - Pollinators Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18347 ER - TY - JOUR T1 - 33/2023 Zweite Änderungssatzung zur Prüfungsordnung für den Masterstudiengang Economics and Finance der Fakultät Gesellschaft und Ökonomie vom 01.09.2023 T3 - Amtliche Bekanntmachungen der Hochschule Rhein-Waal - 2023-33 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18371 VL - 2023 IS - 33 ER - TY - THES A1 - Erkkilä, Julia T1 - Identification of Cas9-nickase Fusions that Promote HDR-mediated Genome Editing N2 - At the heart of this project was the exploration and improvement of the CRISPR/Cas9 gene editing platform with the goal of enhancing efficiency and ensuring safety. The research carried out was primarily concerned with testing and developing a gene editing system that bypasses the need for double strand breaks (DSBs). Given that DSBs are the most damaging events for a cell and pose a major safety risk in genome editing, eliminating them was a key focus of the project. The project aimed to increase the frequency of homology directed repair (HDR) while simultaneously decreasing non homologous end joining (NHEJ), thereby improving the accuracy of genome editing. The methodology involved the use of a Cas9 protein fused to factors involved in DNA repair. Based on previous evidence that this strategy improves the HDR mediated repair of a Cas9 induced DSB, intention here was to apply the same strategy to Cas9 nickases for a safer alternative to standard genome editing procedures. A Cas9 nuclease can be transformed into a Cas9 nickase (nCas9) that cuts only one strand of DNA by mutating one of the two nuclease domains of the Cas9 either via a D10A point mutation for RuvC or an H840A for HNH. Preliminary experiments had shown that using nickases could reduce the occurrence of DSBs at both target and non target sites. However, because genome editing efficiency of nickases is limited, the project focused on amplifying nickase induced HDR frequency by fusing the D10A nCas9 with DNA repair factors that guide the repair of single strand breaks via HDR. Experiments evaluated the ability of each Cas9 nickase to direct the resolution of single strand breaks via HDR. An eGFP or mCherry cassette under its own promoter was employed as a reporter gene to measure the success of the transfection. The experiments were performed in three genomic loci, namely AAVS1, CLYBL, and H2AX. The degree of eGFP or mCherry expression after 14 days, as quantified by flow cytometry, was used to estimate the knock in success. The results obtained support the hypothesis that fusing D10A nCas9 with selected DNA repair factors leads to an increase in the knock in efficiencies as compared to the unmodified nCas9. The choice of the promoter used to express the nuclease, either CMV or CAG, did not seem to influence the knock in efficiencies. Instead, the type of repair template used did influence the knock in efficiencies with nicked plasmid templates contributing to greater HDR levels than non nicked ones. Knock in efficiencies of Cas9 nickases varied depending on which locus they were tested in. More research remains to be done to test alternative Cas9 nickase fusions. However, this approach represents a promising direction for the creation of a more efficient and safer gene editing instrument for clinical use. Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18322 ER - TY - THES A1 - Gauri, Kshama T1 - Feasibility of Pfeiffer’s Circular Chromatography for testing soil and compost quality in the Environmental Labs at HSRW. N2 - The utilization of a simple test, such as Pfeiffer's Circular Chromatography (PCC), has the potential to provide deeper insights into all the parameters affecting soil health. However, despite its promise, the method has yet to attain widespread adoption among farmers and universities, primarily due to challenges in interpreting its outcomes. This thesis investigates the application of PCC as a technique for soil analysis at Hochschule Rhein Waal University. The paper analyses compost and soil samples sourced from the Rhein Ruhr region, focusing on the potential of PCC in determining chemical parameters, including nitrate content, pH, and organic matter quantity. As a result, the aforementioned chemical parameters were documented and the economic viability of the methods were compared to PCC. The development of PCC is dependent on environmental conditions. To explore this aspect, the test was conducted under different lighting conditions and assessed by various researchers to gauge its interpretability. The paper evaluates the test's reliability based on its reproducibility. The PCC results were found to be sensitive to environmental conditions; nevertheless, the method displays potential in assessing overall soil and compost health on a relative scale. The paper suggests improvements to enhance the technique's quality and provides recommendations for further research to explore the various possibilities of PCC and its interpretation. In conclusion, with additional research and data collection on the PCC method coupled with the integration of existing technologies such as machine learning and AI, the potential exists to provide farmers with a rapid technique for assessing their soil. Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18268 ER - TY - THES A1 - Idowu, Adetola T1 - Innovative Solutions to Waste Management: A Case Study of Lagos State, Nigeria. N2 - Lagos State, Nigeria’s most populous city, experiences a continuous increase in its population, resulting in a substantial rise in waste generation from various sources including households, industries, and commercial activities. Unfortunately, the existing waste management infrastructure and practices within the state remain inadequate, giving rise to environmental pollution, health hazards, and the deterioration of urban landscapes. Thus, this study explores innovative and sustainable solutions for waste management in Lagos State. Specifically, this study focuses on two important waste categories; Municipal Solid Waste and Sewage Waste. This study includes a thorough examination of the existing waste management practices in Lagos State through visits and interviews conducted with the relevant waste management authorities within the state. In pursuit of possible solutions to address Lagos State waste challenges, this study draws insights from the waste management practices established in Germany, with a particular focus on Cologne. Additionally, this study evaluates the feasibility and potential effectiveness of implementing these practices in Lagos State. Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18239 ER - TY - JOUR T1 - 32/2023 Einschreibungsordnung der Hochschule Rhein-Waal vom 08.08.2023 T3 - Amtliche Bekanntmachungen der Hochschule Rhein-Waal - 2023-32 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18253 VL - 2023 IS - 32 ER - TY - JOUR T1 - 31/2023 Zweite Änderungssatzung zur Wahlordnung zu den Gremien und Organen der Hochschule Rhein-Waal vom 27.09.2023 T3 - Amtliche Bekanntmachungen der Hochschule Rhein-Waal - 2023-31 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18247 VL - 2023 IS - 31 ER - TY - THES A1 - Hammoudeh, Basil Mazen T1 - The use of biocatalysis in the diagnosis and treatment of colorectal cancer (CRC) N2 - Colorectal cancer is a significant global health burden. Early-stage colorectal cancer is asymptomatic, which, coupled with the fact that later stages of CRC have a very low prognosis, and that current methods of diagnosis and treatment significantly impact the patient, exploring alternate ways to diagnose and treat CRC is vital. Biocatalysis is the use of naturally found catalysts such as nanozymes and enzymes in order to catalyze reactions. Due to their characteristics and uses, biocatalysts are seen as promising alternatives to current methods of CRC diagnosis and therapy. This research-based bachelor thesis aims to summarize and analyze current traditional and biocatalytic methods that exist to diagnose and treat CRC, in order to seek the potential of biocatalysis in this field, as well as discuss its current state and its future in comparison to currently implemented methods. It provides an extensive overview of traditional and biocatalytic approaches to diagnosis and therapy, considering important factors such as efficacy, sensitivity, selectivity, cost, and safety. The thesis also delves into the use of biocatalysis for important points such as the early diagnosis of CRC, and the challenges faced during development, regulation, and monetary concerns. Through careful analysis of the strengths and limitations of techniques in the field, as well as personal opinions on the future of research, conclusions on given hypotheses regarding biocatalysis in CRC diagnosis and therapies were presented and included strong support for the unquestionable potential of biocatalysis use in cancer healthcare, while highlighting possibilities to tap into that potential by scrutinizing their equally as unquestionable current limitations. Overall, this thesis aspires to contribute, on however minuscule a scale, towards the advancement of CRC diagnosis and therapy approaches, with the ambition of improving patient care and prognosis, as well as quality of life for those struggling or who will struggle in the future with the disease, together with their kin who are profoundly affected as well. KW - Colorectal cancer KW - Cancer KW - Biocatalysis KW - Enzymes KW - Diagnosis KW - Therapy Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18147 ER - TY - THES A1 - Langer, Sven T1 - The Impact of Leader Behavior on Team Processes N2 - The modern work environment is subject to constant change with a notable shift from individual to team-based work structures. This transition necessitates an improved un-derstanding of how managerial actions influence the dynamics within these teams, to optimally align them for success. Despite the substantial research about leader effec-tiveness and team effectiveness based on organizational performance indicators, it is rather infrequent that the direct influence of leader behavior on teams is explored. This thesis aims to address this gap by answering how leader behaviors impact team pro-cesses in the context of German medium to large-scale IT-enterprises. Using a quanti-tative cross-sectional methodology, individuals working in team-based structures under direct supervision were surveyed. Analyzing data from 94 respondents via hierarchical linear regression analysis, several significant relationships were identified. In general, leader behavior has a strong positive impact on team processes. Furthermore, task-oriented leaders have the greatest positive influence on action processes, while relation-oriented leaders have the greatest positive influence on interpersonal processes. Change-oriented leaders also significantly influence action processes and interpersonal processes, albeit less strongly than their counterparts. These results provide implications for team management practices, emphasizing the importance of leader behavior for aligning team processes in the direction of success. KW - Leader Behavior KW - Team Processes KW - IT-Management KW - Leader Effectiveness KW - Team Effectiveness Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18136 ER - TY - THES A1 - Saberi, Sabiha T1 - Governance of Global Value Chains in the Garment Industry: The Bangladesh Fire and Building Safety Accord N2 - Global Value Chain (GVC) is a process where production takes places in different countries for different stages. Many of the scholars have argued that social upgrading and economic upgrading is connected as a result of Global Value Chain. This paper is built on the concept of Global Value Chain (GVC) in terms of social upgrading. There will be discussion on the fire incident of “Tazreen Fashion” and another consecutive disaster named as “Rana Plaza Tragedy” and the aftermath of International Labor Organization intervention resulted in “The Bangladesh Accord: Fire and Building safety”. GVC upgrading framework approach and the link between framework and the Accord helps to understand the governance. The Accord analyzed as GVC upgrading tool and addresses the shortcomings of inspection and transparency issues. The paper aims at explain how much the accord has been conducted using GVC upgrading framework. This paper draws a conclusion by analyzing from publicly available secondary data. This paper tries to answer the progress rate of the investigation using descriptive statistics and testing hypothese. The paper aims to shed a light on it and suggests insight after the expiration of the Accord in 2021. KW - ILO KW - RMG KW - Global value chains KW - Global product network KW - Descriptive statistics KW - Progress rate KW - Analysis KW - Effectiveness Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18072 ER - TY - THES A1 - Peschel, Raphaela T1 - Vermehrte Inanspruchnahme deutscher Notfallambulanzen - Eine Patientenbefragung im BG Klinikum Duisburg N2 - Einleitung: Die vermehrte und stetig steigende Inanspruchnahme von Deutschlands Notaufnahmen und das damit einhergehende Crowding innerhalb dieser stellen ein komplexes Problem des Gesundheitssystems dar, welches bereits seit geraumer Zeit konkretes Handeln auf gesundheitspolitischer Ebene fordert (Doan et al., 2019). Die patientenseitigen Beweggründe für die vermehrte Inanspruchnahme wurden dabei bislang nicht hinreichend untersucht (Reinhold et al., 2021). Auf der Grundlage der bisherigen Literatur scheint das Nachfragewachstum jedoch häufig auf Patienten ohne medizinische Notfallindikation zurückzuführen zu sein (Durand et al., 2012). Methode: Im Zeitraum vom 01.10.-30.11.2022 wurde eine quantitative Fragebogenerhebung im BG Klinikum Duisburg durchgeführt. Der Fragebogen besteht aus insgesamt 16 Fragen. Die Datenauswertung basierte dabei auf deskriptiven sowie inferenzstatistischen Analysen und konnte mehrere Unterschiede zwischen einigen Patientengruppen aufdecken. Es wurde ein 95% Konfidenzintervall festgelegt. Ergebnisse: Im Rahmen der Fragebogenerhebung konnten 548 gültige Fragebögen erworben werden. Dabei zeigten sich die Gründe für das vermehrte Inanspruchnahme-Verhalten multifaktoriell. In erster Linie zählten hierzu antizipierte Qualitätsvorteile innerhalb der Notaufnahmen im Vergleich zu ambulanten Versorgungseinrichtungen seitens der Patienten sowie insbesondere die Unkenntnis der Bevölkerung über bestehende Gesundheitsdienstleistungen im Notfall, wie bspw. den ärztlichen Bereitschaftsdienst. Ebenso ist ein genereller Rückgang der Gesundheitskompetenz zu verzeichnen. Diskussion: Grundsätzlich ist eine fehlende medizinische Notfallindikation bei dem Großteil der Notfallpatienten zu verzeichnen. Das rund um die Uhr zur Verfügung stehende Versorgungsangebot der Notaufnahmen zeigt sich äußerst attraktiv für die Patienten und führt nicht zuletzt zu Bequemlichkeitsentscheidungen. Letztlich muss das ambulante Versorgungssystem ausgebaut, die Bevölkerung besser aufgeklärt und der bestehende Status der Gesundheitskompetenz dadurch gefordert sowie gefördert werden. KW - Notaufnahme KW - Vermehrte Inanspruchnahme KW - Crowding KW - Behandlungsdringlichkeit KW - Gesundheitskompetenz KW - Antizipierte Qualitätsvorteile Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18099 ER - TY - THES A1 - Pricken, Lennard T1 - The effect of Covid 19 on Mergers and Acquisitions in Germany in contrast to European Countries. N2 - This paper investigates the impact of the Corona pandemic on M&A activities considering the variables M&A volume, M&A value, GDP, and Covid figures. The aim is to analyze the relationships between the development of the pandemic and M&A activities in five European countries (Germany, the UK, France, Italy, and Spain). With an introduction to the literature published so far on the topic, an excellent introduction to the situations around Corona and the M&A market is already offered. The one or other outlooks are already scientifically proven here and have thus also been very for the following analyses and results. In the first step of the research, we analyze M&A volumes and values in the countries under consideration before and during the pandemic. It can be seen that the number of M&A transactions increased overall during the pandemic, but transaction values were very fluctuating in comparison. This observation certainly reflects the general uncertainties and economic challenges of the pandemic. The next step is correlating Covid figures, M&A activity, and GDP. This shows that the pandemic outbreak led to a short-lived decline in M&A activity, as companies acted more cautiously and held back on transactions due to the uncertainty. However, M&A activity rose again as the economic situation in the countries stabilized, and companies were better able to respond to the pandemic. In addition, the impact of GDP on M&A activity is also examined. It can be seen that GDP was affected in all countries due to lockdowns and restrictions on public life. Nevertheless, there was some resilience in the economy as GDP showed an increase in all countries despite the pandemic. The analysis of the correlation between the variables shows that there is a significant relationship between Covid numbers and M&A activity. The higher the Covid numbers were in a country, the more M&A activity was affected. This suggests that the development of the pandemic had a significant impact on M&A activity. Overall, this work shows that the Corona pandemic significantly impacted M&A activity in Europe. The uncertainty and economic challenges led to a short-lived decline in activity, but the overall number of deals increased. The correlation analysis highlights the links between the pandemic and M&A activity and underscores the importance of thoroughly examining the variable factors influencing M&A decisions under Corona conditions. KW - M&A KW - Mergers and Acquisitions KW - Covid-19 KW - Corona Krise KW - Unternehmensübernahmen Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18047 ER - TY - THES A1 - Puzachenko, Georgii T1 - Unravelling mortality of Perca fluviatilis: Meta-analysis and integration into a physiologically structured population model N2 - Perca fluviatilis is widely distributed food generalist fish across the Europe and Asia (Couture and Pyle, 2015). As a part of the project by Winkelmann et al. (2022), the continuos physiologically structured population model (cPSPM) of P. fluviatilis was established which appeared to have potential points for improvement. In this study, I attempted to modify mortality function of the population model. Hence based on thorough literature research 4 models for mortality estimation mortality as well as the data of life-traits of perch were found. The models include Hoenig-Then (Then et al., 2015), Pauly-Then (Then et al., 2015), Lorenzen (Lorenzen, 2022). and Weibull probability density function as function of weight dependent mortality. The methods were parametrised via arithmetic average of population specific traits and non-parametric least-square method. As a result, the mortality models were compared to each other as well as to the base model. Further on, each mortality model was integrated into cPSPM and stable population was found. At the end only Lorenzen and Weibull models were analysed. As a result of mortality model comparison, it was found that the difference between these models lies mainly in difference of magnitude. Integration of the models into cPSPM showed the potential correlation between the mortality and reproduction. The comparison of simulations results in similarity in population dynamics of our models with experimental data, with main difference in magnitude. Overall results suggest that every model has reason to be applied, and all of them have their own application. In terms of current cPSPM, it would be suggested to consider population dynamics of perch over multiple years period with different mortality method employed for each year to address the issue of variability of population dynamics on yearly basis. Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-18017 ER - TY - THES A1 - Stalnyi, Volodymyr T1 - Controller Design, Implementation, and Comparison on a Ball-on-Wheel Test Rig N2 - This thesis project considers the control of the ball-on-wheel (BOW) system with proportional-integral-derivative (PID) and full-state feedback controllers. The BOW test rig consists of the wheel that is actuated by the electric motor, motor encoder, and laser sensor. The desired outcome is to stabilize the ball around the equilibrium point on top of the wheel. By employing common control design techniques and establishing appropriate Simulink models the controllers for the BOW system were implemented. The dSpace software was used to capture the performance of the controllers, while MATLAB was used for analysis. However, various issues arose during the design and commissioning processes, preventing the state-space controller to achieve the desired outcome. As a result, a performance comparison was conducted based on Simulink models, as the state-space controller design failed to perform adequately on the BOW test rig. These issues were thoroughly explained within the thesis and the implications were summarized in the conclusion. KW - PID Controller KW - State-Space Controller KW - Control Engineering KW - Matlab KW - Simulink Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17933 ER - TY - THES A1 - Galeta, Erja Polina T1 - Medien als politisches Mittel: Propaganda und ihre historische Entwicklung N2 - In der vorliegenden Literaturarbeit wird die Entwicklung von Propaganda anhand des Fortschritts von Massenmedien des 20. Jahrhunderts und der digitalen Wende um 2000 untersucht. Beginnend mit der Beschreibung von Büchern als Medien wird das letzte Jahrhundert chronologisch bis zum Fernsehen behandelt. Dabei werden historische Ereignisse in Verbindung mit der Verwendung von Propaganda gebracht. Mit Beginn des digitalen Zeitalters verlagert sich der Handlungsraum der Propagandamethoden aus der analogen auf die digitale Welt. Auszeichnend sind die Geschwindigkeit und Erreichbarkeit großer Menschengruppen mithilfe des Netzes. Durch die Demokratisierung des Internets in Form des Mitmach-Webs können Nutzende gezielt durch die Verwendung von Algorithmen und von künstlicher Intelligenz gesteuerten Social Bots angeworben werden. Es wird auf die Gefahren von Filterblasen und Echo-Kammern eingegangen, die zu einer Radikalisierung führen können. Vorschläge zur Eindämmung der Instrumentalisierung von sozialen Netzwerken zu Propagandazwecken durch die Verbreitung von Fake News und Verschwörungsnarrativen werden sowohl für Nutzende, Institutionen, der Regierung als auch für Tech-Unternehmen unterbreitet. N2 - The present work examines the development of propaganda based on the progression of mass media in the 20th century and the switch to digital media around the year 2000. Beginning with the description of books, the mass media of the last century is described chronologically up to the topic of television. Historical events are associated with the use of propaganda. With the onset of the digital age, the scope of propaganda methods is shifting from the analogue to the digital world. The risks on the internet of these processes are highlighted. Particularly outstanding is the speed and accessibility of large groups of people with the help of networks. By democratizing the internet with the help of the participatory web, users can be targeted using algorithms and artificial intelligence-driven social bots. The dangers of filter bubbles and echo-chambers, which can lead to radicalization, are discussed. Proposals to curb the exploitation of social networks for propaganda purposes through the dissemination of fake news and conspiracy narratives are laid out to users, institutions, governments and tech companies. KW - Propaganda KW - Massenmedien KW - Digitalisierung KW - Künstliche Intelligenz Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17876 ER - TY - JOUR T1 - 30/2023 Richtlinie zur Eintragung studentischer Vereinigungen in die Matrikel an der Hochschule Rhein-Waal vom 25.04.2023 T3 - Amtliche Bekanntmachungen der Hochschule Rhein-Waal - 2023-30 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17864 VL - 2023 IS - 30 ER - TY - THES A1 - Mezghani, Mohamed Rami T1 - A software architecture and reference implementation based on xAPI for a modular, personalized learning platform N2 - Interactive learning platforms which include multiple modules and components require handling learning data and synchronizing progress across the entities. This thesis aims to create a control layer to manage the learning data and depict it on the user interface, as well as a learning path recommendation system to establish a learning path defined by the teacher. The project extends the pre-existing TierschutzErleben platform, utilizing a stateof-the-art specification for learning data, frontend framework, and a video game engine. A main control unit is developed to manage learning data and coordinate elements of the platform. To recommend learning paths, a system is created, and interfaces are established to validate communication. A service is introduced to relay events between components, with events containing instructions for executing appropriate actions on the receiving end. Additionally, a command execution system is implemented to manage these commands. The implementation of a single control layer, composed of the developed services, effectively coordinates data collected from multiple entities. The use of interfaces and the command execution system provides a clear and structured view of events and their corresponding actions. KW - Xapi learning path interactive platform gamified angular Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17718 ER - TY - JOUR T1 - 29/2023 Richtlinie zur Ausübung des Hausrechts an der Hochschule Rhein-Waal (Hausordnung) vom 05.07.2023 T3 - Amtliche Bekanntmachungen der Hochschule Rhein-Waal - 2023-29 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17784 VL - 2023 IS - 29 ER - TY - JOUR T1 - 28/2023 Zweite Änderungssatzung zur Berufungsordnung der Hochschule Rhein-Waal vom 30.05.2023 T3 - Amtliche Bekanntmachungen der Hochschule Rhein-Waal - 2023-28 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17770 VL - 2023 IS - 28 ER - TY - CHAP A1 - van Bruggen, Jannike A1 - Bockmühl, Dirk A1 - Bruckmann, Dirk A1 - Gebauer, Jens A1 - Reiser, Dirk A1 - Wichern, Florian A1 - Darr, Dietrich T1 - SUFACHAIN - Sustainable Agroforestry Value Chains in Central Asia N2 - The agricultural sector represents an important means of livelihood for the rural population in Central Asia, while the region's agricultural and forest landscapes are at risk of degradation due to population growth and economic development. The SUFACHAIN project aims to analyse agroforestry systems and integrate them into local land use systems, while developing products and technologies that contribute to the sustainable use of resources and create local value. In close collaboration with local partners, the project will (1) analyse and design sustainable agroforestry systems, (2) improve quality in the foods made from agroforestry products, (3) develop efficient technologies for the re-use of waste materials from the processing chain, (4) improve transparency along the supply chain, (5) increase local value by valorising selected ecosystem services and (6) develop attractive market niches for agroforestry products. T3 - Beiträge des Forschungs- und Transfertags der Hochschule-Rhein Waal - 03 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17660 ER - TY - THES A1 - Tannhäuser, Tristan T1 - Methodenentwicklung zur Bestimmung des Serumspiegels und der Stabilität von Bupropion und Hydroxy-Bupropion mittels LCMS Orbitrap im Zuge des therapeutischen Drug Monitorings N2 - Patients undergoing psychiatric treatment are typically treated with a variety of medications, the interactions of which and the resulting impact on the serum concentration levels of the drugs are unpredictable. Such interactions and the occurrence of side effects due to incorrect dosages are also known for the antidepressant bupropion, emphasizing the importance of therapeutic drug monitoring for this medication. Therefore, this study aimed to develop and validate a method for the determination of serum levels of bupropion and its pharmacologically active major metabolite, hydroxybupropion, using LC-MS. Additionally, due to the low stability of bupropion at room temperature, the influence of this factor on the routine measurements of bupropion patient samples in the laboratory of the LVR-Klinik Viersen pharmacy was also examined. Various bupropion solutions (dissolved in methanol or human albumin) were prepared for measurement. These solutions were analyzed using an LC-MS "Exactive Plus Orbitrap" with a biphenyl column as the stationary phase and various mobile phases differing in polarity to allow for the generation of a gradient. An electron spray ionization (ESI) method and an Orbitrap detector were used for quantifying the sample concentration. The measurement of a 0.1 ng/ml bupropion solution and a 0.5 ng/ml hydroxybupropion solution resulted in a signal-to-noise ratio in the mass spectrum that was well above the required 3:1 ratio for background noise subtraction. As the concentration was already below the required detection limit of 0.2 ng/ml for bupropion and 17 ng/ml for hydroxybupropion, no further steps were taken to determine the actual limit of detection for economic reasons since sufficient sensitivity of the LC-MS method was already demonstrated. The investigations into the recovery rate (WFR) and ion suppression showed that the applied sample preparation (protein precipitation with acetonitrile) did not lead to any relevant loss of content and that no interfering effects from other components of the sample matrix occurred during the measurement. The WFR was determined to be 100 ± 5% for bupropion and 101 ± 4.8% for hydroxybupropion. The examination of ion suppression resulted in a content deviation from the target value of 4 ± 0.2% for bupropion and -9 ± 0.1% for hydroxybupropion. The linearity of the method was confirmed by measuring a 5-point calibration with a correlation coefficient for the regression line of approximately 0.99 for both analytes. The precision and reproducibility of the method were also confirmed through the evaluation of in-day and day-to-day variation, with a coefficient of variation of <10 for all measurements conducted for both analytes. Thus, a reliable method for the determination of bupropion content using LC-MS was successfully developed and validated. By participating in proficiency testing programs, the method will be further validated and potentially certified in the future. N2 - Patienten in psychiatrischer Behandlung werden in der Regel mit einer Vielzahl von Medikamenten behandelt, deren Wechselwirkungen und der daraus resultierende Einfluss auf die Serumspiegelkonzentration der Arzneistoffe nicht vorhersehbar sind. Auch für das Antidepressivum Bupropion sind solche Wechselwirkungen, sowie das Auftreten von Nebenwirkungen aufgrund falscher Dosierungen in der Therapie bekannt und unterstreichen die Bedeutung des therapeutischen Drug Monitorings für diesen Wirkstoff. In dieser Arbeit sollte daher eine Methode zur Serumspiegelbestimmung von Bupropion und seinem pharmakologisch wirksamen Hauptmetaboliten Hydroxy-Bupropion für die LCMS entwickelt und validiert werden. Aufgrund der geringen Stabilität von Bupropion bei Raumtemperatur, sollte zudem überprüft werden, welchen Einfluss dies auf die Routinemessungen von Bupropion-Patientenproben im Labor der Apotheke der LVR-Klinik Viersen hat. Es wurden verschiedene Bupropion Lösungen (in Methanol oder Humanalbumin gelöst) für die Vermessung hergestellt. Diese wurden auf einer LCMS „Exactive Plus Orbitrap“ unter Verwendung einer Biphenyl-Säule als stationäre Phase und diverser Fließmittel, die sich in ihrer Polarität unterschieden und so die Erzeugung eines Gradienten ermöglichten, analysiert. Als Ionisationsverfahren kam eine Elektronensprayionisation (ESI), sowie ein Orbitrap-Detektor zur Quantifizierung der Probenkonzentration zum Einsatz. Die Vermessung einer 0,1 ng/ml Bupropion-Lösung und einer 0,5 ng/ml Hydroxy-Bupropion-Lösung ergaben ein Signal-Rausch-Verhältnis im Massenspektrum, welches weit über dem erforderlichen 3:1-Verhältnis für die Abhebung vom Hintergrundrauschen lag. Da die Konzentration bereits unterhalb der erforderlichen Messempfindlichkeit von 0,2 ng/ml für Bupropion bzw. 17 ng/ml für Hydroxy-Bupropion lag, wurden aus wirtschaftlichen Gründen keine weiteren Schritte zur Bestimmung der tatsächlichen Nachweisgrenze unternommen, da eine ausreichende Empfindlichkeit der LCMS bereits belegt war. Die Untersuchungen zur Wiederfindungsrate (WFR) und der Ionensupression konnten zeigen, dass die verwendete Aufbereitung (Proteinfällung mit Acetonitril) zu keinem relevanten Gehaltsverlust führt und keine störenden Effekte durch andere Bestandteile der Probenmatrix während der Vermessung auftreten. Es ergab sich eine WFR für Bupropion von 100 ± 5 % und für Hydroxy-Bupropion von 101 ± 4,8 %. Bei der Untersuchung zur Ionensuppression kam es zu einer Gehaltsabweichung vom Zielwert von 4 ± 0,2 % für Bupropion und von -9 ± 0,1 % für Hydroxy-Bupropion. Die Linearität der Methode wurde durch die Vermessung einer 5-Punkt-Kalibration mit einem Korrelationskoeffizienten für die Regressionsgerade von ~0,99 für beide Analyten bestätigt. Durch die Überprüfung der In-Day- und Day-to-Day-Variation konnte auch die Präzision und Reproduzierbarkeit der Methode bestätigt werden. Dabei ergab sich ein Variationskoeffizient für alle durchgeführten Messungen von <10 für beide Analyten. Somit konnte erfolgreich eine zuverlässige Methode für die Gehaltsbestimmung von Bupropion mittels LCMS entwickelt und validiert werden. Durch das Integrieren von Bupropion in die Teilnahme an Ringversuchen, wird die Methode in Zukunft auch weiter validiert und ggf. zertifiziert werden. Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17690 ER - TY - CHAP A1 - Watson, Conor A1 - Rummel, Pauline A1 - Beule, Lukas A1 - Schlösser, Charlotte A1 - Hemkemeyer, Michael A1 - Schwalb, Sanja A1 - Preißing, Timo A1 - Vögerl, Jakob A1 - Wichern, Florian T1 - Excellent excrement? The potential benefits and drawbacks of soil amendment with frass N2 - Insect rearing is a rapidly growing sector in Europe, with larval protein production projected to exceed 1 Mt in 2025. The by-product frass is a mix of larval faeces, exoskeletons and undigested substrate. Given its potential as a soil improver, frass could make insect production a “zero waste” industry. However, its positive reputation has not been thoroughly scrutinized with regard to environmental impacts. We therefore conducted experiments to investigate the effects of frass application on the soil microbial community, release of greenhouse gases and heavy metal availability. The main conclusions were: 1) Frass is nutritious and can benefit the soil microbial biomass, but rapid loss of C and N reduces its fertiliser and organic amendment potential 2) Co-application of frass with urease inhibitors could allow it to be utilised as a slow-release N fertiliser 3) Concurrent soil amendment of frass with nitrification inhibitors prevents soil nitrite accumulation 4) All frass types tested are suitable as ameliorative amendments to heavy-metal contaminated soils T3 - Beiträge des Forschungs- und Transfertags der Hochschule-Rhein Waal - 05 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17689 ER - TY - CHAP A1 - Hansen, Ute A1 - Huth, Miriam A1 - Platte, Frank A1 - Stawicki, Piotr A1 - Struck, Alexander A1 - Tewes, Thomas A1 - Wenda, André T1 - Entwicklung innovativer Verfahren zur mikrobiologischen Qualitätsüberwachung in Echtzeit N2 - Entwicklung biophysikalischer Verfahren zur schnellen Identifikation mikrobieller Kontaminationen in Gewässern – Vorstellung des InnoMiBiQ-Projektes Ute Hansen1, Miriam Huth2, Frank Platte2, Piotr Stawicki3, Alexander Struck3, Thomas J. Tewes2, André Wenda1 1 Fakultät Kommunikation und Umwelt, Hochschule Rhein-Waal, Friedrich-Heinrich-Allee 25, 47475 Kamp-Lintfort 2 Fakultät Life Sciences, Hochschule Rhein-Waal, Marie-Curie-Straße 1, 47533 Kleve 3 Fakultät Technologie und Bionik, Hochschule Rhein-Waal, Marie-Curie-Straße 1, 47533 Kleve Daten zur mikrobiellen Wasserbelastung liegen bei Anwendung etablierter Standardmethoden erst nach Tagen vor. Ziel des InnoMiBiQ Projektes ist die Entwicklung eines schnellen biophysikalischen Verfahrens zur Identifikation mikrobieller Kontaminationen in Gewässern. Gefördert wird das Projekt mit zweijähriger Laufzeit im Rahmen des Focus Forschung HAW Programms des Ministeriums für Kultur und Wissenschaft des Landes Nordrhein-Westfalen. Die Förderlinie FF HAW-Kooperation zielt auf eine verbesserte HS-interne interdisziplinäre Kooperation und den Auf- und Ausbau eines attraktiven Forschungsschwerpunkts. Ausgangspunkt der Arbeiten war das in der Arbeitsgruppe von F. Platte und in Kooperation mit der AG Hygiene (Prof. Bockmühl) von T. Tewes entwickelte Verfahren zur Identifizierung von Mikroorganismen mit Hilfe der Raman-Spektroskopie. Experimentelle Arbeiten wurden zu der Frage durchgeführt, ob die Methodik für die Identifizierung einzelner Bakterien in Gewässerproben anwendbar ist und welche Probenvorbehandlungs- und Datenverarbeitungsprozeduren unter Berücksichtigung der Automatisierbarkeit erforderlich sind. Die Ergebnisse bzgl. der Raman-spektroskopischen Identifizierung der Bakterienzellen waren vielversprechend. Problematisch ist allerdings, dass es gilt, wenige bakterielle Zellen zwischen einer sehr großen Zahl anderer Partikel zu identifizieren. Ideen für ein Raman-basiertes schnelles Partikel-Scan-Verfahren wurden entwickelt. Untersucht wurde auch, ob neben Mikroorganismen weitere Wasserkontaminationen mit Hilfe der Raman-Spektroskopie nachweisbar sind. Hier standen Verunreinigungen durch Mikroplastik (speziell Reifenabrieb), Ölfilme, Sulfat und Nitrat im Mittelpunkt. Im Rahmen zahlreicher „networking“-Aktivitäten wurden Kontakte zu Herstellern von Partikelmess-Systemen aufgebaut und Kooperationen mit Anbietern von Raman-Spektrometern initiiert mit dem Ziel, über F&E Projekte die Entwicklung eines kontinuierlich arbeitenden des Raman-Systems voranzubringen. Projektskizzen wurden entwickelt und Anträge auf Forschungsförderung eingereicht. Dass schnelle, kontinuierlich arbeitende biophysikalische Verfahren zur Identifikation von Gewässer-Kontaminationen erforderlich sind, wurde von potentiellen Anwendern bestätigt. Nur eine zeitlich hoch aufgelöste Überwachung der Wasserqualität kann Katastrophen wie das Fischsterben in der Oder verhindern. T3 - Beiträge des Forschungs- und Transfertags der Hochschule-Rhein Waal - 06 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17674 ER - TY - CHAP A1 - Lamik, Jonas T1 - Publikationsfonds der Hochschule Rhein-Waal. Rahmendaten und Förderkriterien N2 - Die Bibliothek der Hochschule Rhein-Waal unterstützt bereits seit mehreren Jahren Open-Access-Veröffentlichungen, um digitale wissenschaftliche Information ohne finanzielle, gesetzliche oder technische Einschränkungen zugänglich zu machen. Um das Publikationsaufkommen qualitativ und quantitativ weiterzuentwickeln, steht ab dem Haushaltsjahr 2023 an der Hochschule Rhein-Waal erstmals ein Fonds für Ausgaben im Zusammenhang mit Open-Access-Publikationen bereit. Der Publikationsfonds umfasst 100.000 € und steht, verwaltet von der Bibliothek, ab sofort zur Verfügung. Das Poster stellt vor, welche Publikationstypen gefördert werden können, welche Kriterien für eine Förderfähigkeit erfüllt sein müssen und welche weiteren Publikationsdienstleistungen die Bibliothek anbietet. Darüber hinaus wird ein kurzes Schlaglicht auf die weitere Entwicklung des Publikationsfonds und der Publikationsförderung geworfen. T3 - Beiträge des Forschungs- und Transfertags der Hochschule-Rhein Waal - 04 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17613 ER - TY - CHAP A1 - Merbecks, Ute T1 - Corporate Digital Responsibility in Germany N2 - Corporate Digital Responsibility (CDR) is a recently developing new management concept in response to the increasing challenges caused by digital transformation. In Germany, this self-governance approach influenced the political discussions and led to a more integrative and collaborative multi-policy strategy beyond pure regulatory regimes. The launch of the German CDR-code by the German action group in June 2021 is a milestone to capture ethical problems in digitalised firms by voluntary commitments from signatories. However, little empirical evidence on the current state of CDR-initiatives at German corporations is available up-to now. This project addresses the identified research gap by performing a qualitative analysis of the disclosed information on CDR in nonfinancial reports of the DAX 30 companies from 2020. T3 - Beiträge des Forschungs- und Transfertags der Hochschule-Rhein Waal - 02 KW - Corporate Digital Responsibility KW - Digitalisation KW - Sustainability Reporting KW - Corporate Responsibility KW - Business Ethics Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17637 ER - TY - JOUR T1 - 27/2023 Erste Änderungssatzung zur Praktikumsordnung der Fakultät Technologie und Bionik für Ingenieurwissenschaftliche Studiengänge an der Hochschule Rhein-Waal vom 19.01.2023 T3 - Amtliche Bekanntmachungen der Hochschule Rhein-Waal - 2023-27 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17583 VL - 2023 IS - 27 ER - TY - JOUR T1 - 26/2023 Erste Änderungssatzung zur Praktikumsordnung für den Bachelorstudiengang Biomaterials Science der Fakultät Technologie und Bionik an der Hochschule Rhein-Waal vom 19.01.2023 T3 - Amtliche Bekanntmachungen der Hochschule Rhein-Waal - 2023-26 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17577 VL - 2023 IS - 26 ER - TY - THES A1 - Ferraresi Moura, Rafaela T1 - How Could a Global Company Communicate and Work Interculturally? Detecting Cultural Patterns of Communication to Successfully Work in a Global Company N2 - This research considers the hidden aspects of culture suggested by Edward T. Hall and Joseph Shaules, when referring to intercultural communication. It uses the cultural dimensions from Erin Meyer, Geert Hofstede, and Richard Lewis to explain cultural misunderstandings between the German and Indian teams of a multinational. It also considers the Expectancy Violations Theory from Judee K. Burgoon to improve communication among dissimilar cultures. KW - Intercultural communication KW - Intercultural studies KW - Social psychology KW - Macro-Culture KW - Cultural dimensions Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17563 ER - TY - THES A1 - Navid, Sina T1 - Real-Time Web Application for Decision Support in Groundwater Management N2 - Groundwater is an essential resource that is used for a wide range of purposes all over the world, and retaining this important natural asset demands that it be managed and utilized sustainably. Despite the fact that groundwater is frequently abundant and widely utilized, it is difficult and costly to precisely estimate water levels when compared to surface water systems. Groundwater managers require improved digital tools to understand the system state of the aquifers they seek to interact with sustainably (e.g., accessing real-time updates on the state of the water table to check whether pumping operation is achieving or violating a desired drawdown target.) Here we propose a workflow for a pilot region that (a) temporally interpolates irregularly, manually-measured water levels in a real observation network using data from neighboring sensor-equipped observation, using a multiple linear regression approach to reduce complexity. The resulting interpolated time series are then used in conjunction with the sensor data to come up with (b) spatial interpolations of the groundwater field over time using inversed distance weighting (IDW) at any given point in time. From that, spatial estimates of the groundwater field can be transformed into maps of deviation from drawdown targets. We visualize these targets and their temporal evolution for groundwater managers in real-time on a web application. The web application displays these maps together with operational data (e.g., extraction rates) and meteorological data (recent and forecasted precipitation rates). It serves as a foundational tool for groundwater management when making control decisions to save energy in climate change mitigation and to reduce costs. KW - Groundwater KW - Web application KW - Plotly Dash KW - Data Engineering KW - Data visualizing Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17550 ER - TY - JOUR T1 - 25/2023 Ordnung der Hochschule Rhein-Waal über das Verfahren und die Vergabe von Leistungsbezügen vom 31.05.2023 T3 - Amtliche Bekanntmachungen der Hochschule Rhein-Waal - 2023-25 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17547 VL - 2023 IS - 25 ER - TY - JOUR T1 - 24/2023 Erste Änderungssatzung zur Wahlordnung zu den Gremien und Organen der Hochschule Rhein-Waal vom 08.05.2023 T3 - Amtliche Bekanntmachungen der Hochschule Rhein-Waal - 2023-24 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17534 VL - 2023 IS - 24 ER - TY - THES A1 - Schmidt, Sören T1 - Offshore Wind Farms - The new kind of Marine Protected Area for Northern Europe? N2 - This thesis combines the findings of several publications and studies on the influ- ence of offshore wind farms on marine life, in Northern Europe. The properties and characteristics of this offshore wind farm areas were compared to the characteristics of marine protected areas and differences as well as conformities were highlighted. It is evident, that the negative consequences accompanying the implementation of offshore wind farms are less concise, than the public opinion assumes. Although scientific knowledge gaps in multiple related fields for example, the influence of elec- tromagnetic fields on individuals or the influence of noise on benthos species, are present, offshore wind farms offer chances to contribute positive effects for marine life in terms of de facto protected areas and new possibilities for population growth. The planned extensions of offshore wind farms in geographical relation to marine protected areas could enhance the size of protected areas and connect remote ma- rine protected areas with each other. Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17490 ER - TY - THES A1 - Büsch, Ida T1 - Decades in Deadlock: Analysis of the Intergovernmental Discourse among Middle Eastern States about a Weapons of Mass Destruction-Free Zone in their Region N2 - Despite intense international efforts to make progress regarding the establishment of a Middle Eastern Weapons of Mass Destruction-Free Zone (ME WMDFZ), governments have spent decades in deadlock on the issue. This thesis examined the intergovernmental discourse among Middle Eastern states about the proposed zone by analyzing the prevalent topics and sentiments of Middle Eastern governments in the discourse. The thesis applied a quantitative approach, in which documents from an international context about a ME WMDFZ were analyzed using computational text analysis and interpreted by drawing on models of political discourse analysis. The conducted analysis contributed to close a research gap related to the evolution of the discourse on a ME WMDFZ and explored the application of computational text analysis to political documents. KW - Arms control KW - Disarmament KW - Middle East KW - Nuclear weapons KW - United Nations Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17465 ER - TY - THES A1 - Steup, Maike T1 - Untersuchung der Präferenzen der Generationen Z und Y bei der Arbeitgeberwahl unter Betrachtung der Arbeitgeberattraktivität - eine empirische Untersuchung N2 - Das Ziel der vorliegenden Bachelorarbeit ist die Präferenzen der Generation Z und Y gemessen an der Arbeitgeberattraktivität zu analysieren und entsprechend zu vergleichen. Dazu wurden 93 Studierende in einer quantitativen Onlineumfrage befragt. Die Umfrage basiert auf der Employer Attractiveness Scale von Berthon, Ewing & Ha aus dem Jahr 2005 sowie auf der Authentic Living Scale von Wood et al. aus dem Jahre 2008. Ergänzungen wurden in den Bereichen ethischer Diversität, Unternehmenskultur, Glaubwürdigkeit, Authentizität und persönliche Werte vorgenommen. Diese Aspekte sind im Fragebogen von Berthon, Ewing & Ha im Vergleich mit anderen Arbeitsattraktivitätsmodellen, beispielsweise das Treiberfaktorenmodell von Nagel (2011), unterrepräsentiert, haben allerdings laut einer umfassenden Literaturrecherche für die jungen Generationen Z und Y an Wichtigkeit zugenommen. Die Ergebnisse liefern einen umfassenden Vergleich zu allgemeinen Aspekten der Präferenzen beider Generationen an den Arbeitgeber. Die jungen Generationen unterscheiden sich nur leicht voneinander, was aufwändige Anpassungen an HR-Strategien und Praktiken nicht notwendig macht. Die Bachelorarbeit ist für jegliches Unternehmen interessant, das ihre Zielgruppen (Generation Y & Z) zum Zweck der Rekrutierung besser verstehen möchte. Die Ergebnisse können in Recruiting- und Employer Branding Maßnahmen adaptiert werden. KW - Employer Branding KW - Generation Z KW - Generation Y Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17447 ER - TY - RPRT ED - Zimenkova, Tatiana ED - Ascani, Katrin T1 - Days of Antidiscrimination 3 N2 - This brochure shows the results and impressions of the five-day event “Days of Antidiscrimination 3” at Rhine-Waal University of Applied Sciences, which took place from November 28 to December 2, 2022. The Vice-President for Internationalisation and Diversity and the AStA jointly organized this exchange of all university members and, with this report, make visible the voices of the participants, the expertise of the academics and activists and the contributions of the students. T3 - Days of Antidiscrimination - 3 KW - Antidiscrimination KW - DoA KW - Diversity KW - Antiracism Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17405 ER - TY - THES A1 - Fischer, Alexander T1 - Workplace Health Promotion through Physical Activity Programs Private Economic Return: A Prospective Partial Cost Benefit Analysis for German Firms N2 - Increasing levels of inactivity in contemporary work and lifestyle and the consequent rise in chronic disease have necessitated public health intervention, delivered particularly through the workplace setting. The purpose of this thesis is to provide information on the economic ramifications of such workplace health promotion programs in the field of physical activity to allow for data-based investment decisions of firms. Within a cost-benefit evaluation framework, this thesis identified relevant costs and benefits from practically oriented literature. While most outcomes have been found inconclusive, reductions in absenteeism might be appropriately evidenced and sufficiently tangible to allow quantification. Based on population-attributable risk and insurance data, per employee 0.38-0.58 absence days, or 47.17-71.08€ were estimated to be solely attributable to physical inactivity. Oppositely, cost magnitude depends largely on the interventions’ format, cost-effectiveness, and especially the time investment of the participant. Yet, the economic evidence is largely restricted and demands further investigation. KW - Cost benefit analysis KW - Workplace health promotion KW - Physical activity KW - Economic impact KW - Work related outcomes Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17375 ER - TY - JOUR T1 - 23/2023 Fakultätsordnung der Fakultät Technologie und Bionik an der Hochschule Rhein-Waal vom 12.04.2023 T3 - Amtliche Bekanntmachungen der Hochschule Rhein-Waal - 2023-23 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17368 VL - 2023 IS - 23 ER - TY - JOUR T1 - 22/2023 Dritte Änderungssatzung zur Grundordnung der Hochschule Rhein-Waal vom 13.02.2023 T3 - Amtliche Bekanntmachungen der Hochschule Rhein-Waal - 2023-22 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17353 VL - 2023 IS - 22 ER - TY - THES A1 - Pramanik, Lukas T1 - Digitale Selbstwirksamkeit als Schlüssel zur Arbeitszufriedenheit im demographischen Wandel. Der Mediierende Effekt digitaler Selbstwirksamkeit auf die Beziehung zwischen Alter und Arbeitszufriedenheit. N2 - Die kontinuierliche Digitalisierung der Arbeitswelt führt zu immer schnelllebigeren und komplexeren Arbeitsumfeldern, welche auf der effektiven Nutzung von Informations- und Kommunikationstechnologien (IKT) beruhen. Arbeitsfelder transformieren und verdichten sich mit rasanter Geschwindigkeit. Parallel steigt das durchschnittliche Alter der arbeitnehmenden Population und die Arbeitszufriedenheit sinkt. Besonders betroffen sind Erwachsene gehobenen Alters. Da die Arbeitszufriedenheit als starker Prädiktor für die physische- und psychische Gesundheit der Arbeitnehmenden wirkt, ist es notwendig zu verstehen, welche Konstrukte auf die Arbeitszufriedenheit wirken. Die vorliegende Studie betrachtet daher die mediierende Wirkung der digitalen Selbstwirksamkeit auf die Beziehung zwischen Alter und Arbeitszufriedenheit. Es wurde eine online-Befragung mit 124 Arbeitnehmenden im Alter von 17-63 Jahren durchgeführt. Es wurde erwartet, dass steigendes Alter in einer negativen Beziehung zu Arbeitszufriedenheit und digitaler Selbstwirksamkeit steht. Zusätzlich wurde angenommen, dass digitale Selbstwirksamkeit positiv auf Arbeitszufriedenheit wirkt. Es wurde eine indirekte Mediation, mit einer negativen Wirkung von Alter auf Digitale Selbstwirksamkeit und einer positiven Wirkung von digitaler Selbstwirksamkeit auf Arbeitszufriedenheit identifiziert. Die Wirkung der Geschlechtsidentifikation als Störvariable konnte ausgeschlossen werden. Praktische und theoretische Implikationen werden diskutiert. KW - Digitale Selbstwirksamkeit KW - Digitalisierung KW - Demographie Wandel KW - Arbeitszufriedenheit Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17339 ER - TY - JOUR T1 - 21/2023 Gleichstellungsquoten zur Gewährleistung der Chancengerechtigkeit von Frauen und Männern bei der Berufung von Professorinnen und Professoren der Fakultät Kommunikation und Umwelt an der Hochschule Rhein-Waal T3 - Amtliche Bekanntmachungen der Hochschule Rhein-Waal - 2023-21 Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:1383-opus4-17325 VL - 2023 IS - 21 ER -