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  <doc>
    <id>1608</id>
    <completedYear/>
    <publishedYear>2022</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>88</pageNumber>
    <edition/>
    <issue/>
    <volume/>
    <type>bachelorthesis</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2022-10-26</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>2022-07-20</thesisDateAccepted>
    <title language="eng">CRISPR technology in human medicine: advantages and disadvantages over traditional treatments</title>
    <abstract language="eng">Genome editing tools hold tremendous potential in fighting various diseases via editing specific sites within the target gene of interest of distinct cell types. Among these tools, CRISPR has shown several advantages over alternative nucleases, such as ease of design, high efficiency, and low cost. In this work, a comprehensive review of the existing research on the application of CRISPR technology to the treatment of human diseases is presented. These diseases include monogenic and infectious diseases, as well as conditions for which immunotherapies are typically applied, such as cancer and autoimmune disorders. Following this review is an analysis of the advantages and disadvantages of CRISPR-based strategies compared to traditional treatments in a selection of diseases; this aims to demonstrate the overall potential of CRISPR therapeutic applications in humans and the need for further investigation and development.</abstract>
    <identifier type="urn">urn:nbn:de:hbz:1383-opus4-16080</identifier>
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    <enrichment key="opus.doi.autoCreate">false</enrichment>
    <enrichment key="opus.urn.autoCreate">true</enrichment>
    <licence>CC BY 4.0 International - Namensnennung</licence>
    <author>Mahmoud Karssli</author>
    <collection role="institutes" number="">Fakultät Life Sciences</collection>
    <thesisPublisher>Hochschule Rhein-Waal</thesisPublisher>
    <thesisGrantor>Hochschule Rhein-Waal</thesisGrantor>
    <file>https://opus4.kobv.de/opus4-rhein-waal/files/1608/Karssli_Thesis.pdf</file>
  </doc>
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