@misc{Luthmann, type = {Master Thesis}, author = {Luthmann, Sarah}, title = {Physician Assistants - Rechtliche Lage, Wirtschaftlichkeit und Einsatz am Beispiel des Evangelischen Krankenhaus Wesel}, school = {Hochschule Rhein-Waal}, abstract = {Im Gesundheitswesen, wird das Thema Fachkr{\"a}ftemangel zunehmend zum Problem. Um insbesondere dem {\"A}rztemangel entgegenzutreten, wird verst{\"a}rkt auf Arztassistenzberufe gesetzt. Daher ist es notwendig den gesetzlichen Rahmen und die zwischenmenschlichen Aspekte des Einsatzes von bspw. Physician Assistants zu verstehen. Das Ziel der vorliegenden Arbeit ist es zu beantworten, welchen Spielraum es bei der Delegation {\"a}rztlicher T{\"a}tigkeiten an nicht-{\"a}rztliches Personal gibt, wie die Zusammenarbeit zwischen den unterschiedlichen Berufsgruppen abl{\"a}uft und wie sich der Einsatz von Physician Assistants im Vergleich zu medizinischen Fachangestellten wirtschaftlich darstellt. Um die Forschungsfragen zu beantworten, wurden Experteninterviews mit Angeh{\"o}rigen verschiedener medizinischer Berufsgruppen im Krankenhaus gef{\"u}hrt, zus{\"a}tzlich ist eine Literaturrecherche erfolgt. Es wurden Pflegekr{\"a}fte, Physician Assistants sowie {\"a}rztliches Personal befragt. Deren Aussagen wurden dann im Kontext der Literatur sowie mit den Aussagen eines Fachanwalts f{\"u}r Medizinrecht diskutiert. Die Ergebnisse zeigen, dass die Delegation von {\"a}rztlichen T{\"a}tigkeiten an nicht-{\"a}rztliches Personal unter bestimmten Voraussetzungen m{\"o}glich ist. Die Delegation ist jedoch bei T{\"a}tigkeiten, die unter Arztvorbehalt stehen, begrenzt. In diesen F{\"a}llen k{\"o}nnen lediglich vorbereitende oder assistierende Aufgaben durch nicht-{\"a}rztliche Mitarbeitende erfolgen. Die Zusammenarbeit mit Physician Assistants mit dem Pflegedienst ist sehr gut. Beim {\"a}rztlichen Dienst h{\"a}ngt diese von den individuellen Erfahrungen und der Hierarchieebene ab. Außerdem zeigen die Ergebnisse, dass Physician Assistants im Vergleich zu Medizinischen Fachangestellten einen Mehrwert bei der Arztentlastung bieten, der sich unter gewissen Voraussetzungen auch wirtschaftlich auszahlt. Weiterf{\"u}hrende Forschungen k{\"o}nnten den Einsatz von Physician Assistants im ambulanten Bereich des Gesundheitssektors untersuchen.}, language = {de} } @masterthesis{Tran, type = {Bachelor Thesis}, author = {Tran, Tung}, title = {Development and Implementation of a Cascade Torque Controller for a Motor Test Rig}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-16663}, school = {Hochschule Rhein-Waal}, pages = {144}, abstract = {Servo systems play an important role in the field of automation thanks to their great actuation capability. The majority of industrial servos rely on feeding back armature current for torque control based on the torque-current linear relationship. However, system non-linearity like input delay or external disturbances can make the built-in control mode no longer yields acceptable torque response. This thesis deals with two servo systems in coupling with a torque transducer on a motor test rig as part of a Hardware-in-the-Loop setup. The motor torque step response exhibits a large steady-state error and significant overshoot behavior. This thesis work takes two different approaches to develop a cascade controller that gives desired torque performance. One method is the popular PID control logic and the second is the modern State-Feedback Control architecture using Pole Placement technique. The controller design process is carried out based on an estimated plant model obtained from grey box system identification with experiment data. The designed cascade controllers are implemented and tested on the HIL system with different use cases and yield improved torque transient response with near-zero steady-state error and less than 5\% overshoot under step input in both stationary and rotating conditions. The outer loop controllers are also able to reject intermittent disturbance and track low-frequency input better than the original system. The developed cascade control systems are characterized by high stability margins but limited bandwidth, hence not being able to compensate for the dynamic disturbance of frequency larger than 2.5 Hz. Overall, there are not many differences between the performance of the two control laws, as both can satisfy the system performance requirements.}, language = {en} } @masterthesis{Sadeghi, type = {Bachelor Thesis}, author = {Sadeghi, Yasaman}, title = {Fermentation production process of hyaluronic acid}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-16618}, school = {Hochschule Rhein-Waal}, pages = {58}, abstract = {Hyaluronic acid is an anionic and naturally produced polysaccharide with an unbranched formation, with two alternating disaccharide units (β-1, 3-N-acetyl glucosamine, and β-1, 4-glucuronic acid), which has various medical and pharmaceutical applications due to its wide variety of unique and natural functions and characteristics. Hyaluronan is essential in treating joint diseases by reducing inflammation in osteoarthritic joints, from which so many people suffer worldwide, and the demand for this product is increasing. The industrial production of hyaluronic acid has improved over time. The industrial production process is primarily based on the extraction of hyaluronic acid from animal tissues and the biotechnological application of microorganisms for hyaluronic acid biosynthesis that produce high molecular weight hyaluronan molecules. Using microorganisms is the most favorable method for large-scale hyaluronic acid production. This study focuses on designing hyaluronic acid production using Streptococcus zooepidemicus and SuperPro Designer to obtain a suitable yield of injectable HA to treat knee-related problems. Two cases have been developed. Case A is the baseline scenario, mainly focused on producing injectable hyaluronic acid, and case B is an elevated and optimized scenario to achieve a higher amount of injectable HA. Both processes include upstream processing, primary recovery, purification, production of injectable hyaluronan, and isopropanol distillation. The upstream section contains the fermentation process and the inoculum preparation by seed training. The fermentation step was set to work in fed-batch mode, and aeration was applied to increase the final yield. The primary recovery section encompasses crossflow filtration. This process starts with the centrifugation of the broth in disk-stack centrifugation, and purification includes Granular Activated Carbon adsorption, isopropanol precipitation, basket centrifugation, diafiltration, spray drying, and freeze-drying. Ultimately, the cost of raw materials, labor, equipment purchase, annual operating, waste treatment, and utilities are analyzed in the economic evaluation. The selling price was estimated to be \$2000 per kg of HA for the cosmetic industry and \$50,000 per kg for injections. Additionally, sensitivity analysis is performed to predict the outcome of any changes in a variable and assist the producers in decision-making processes.  }, language = {en} } @misc{OPUS4-1658, title = {2/2023 Erste {\"A}nderungssatzung zur Zugangsordnung f{\"u}r den Masterstudiengang Information Engineering and Computer Science der Fakult{\"a}t Kommunikation und Umwelt an der Hochschule Rhein-Waal vom 27.10.2022}, volume = {2023}, number = {02}, organization = {Hochschule Rhein-Waal}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-16588}, pages = {4}, language = {de} } @masterthesis{Geurts, type = {Bachelor Thesis}, author = {Geurts, Nick}, title = {Photodecompostion of Sodium Dodecyl Sulfate Using a UV/H2O2 Reactor with Ultraviolet-C Light Emitting Diodes}, school = {Hochschule Rhein-Waal}, abstract = {Anionic surfactants are used in many common household products, such as dishwashing detergents or soaps. Sodium dodecyl sulfate (SDS) is one of the most prominent surfactants and can cause substantial damage to the environment. Removal from wastewater is therefore a significant problem. This thesis investigates the photochemical decomposition of SDS using ultraviolet-c light emitting diodes (UV-C LEDs) and hydrogen peroxide. The experiments were performed with a surfactant concentration of 10 mg L which is actually found in wastewater after hand washing. Direct exposure to UV radiation to destroy organic compounds is generally seen as inefficient and consumes a large amount of energy. Adding hydrogen peroxide significantly increased the destruction rate due to the UV-induced formation of hydroxyl radicals. It was also investigated how the effectiveness of the reactor can be further increased. The use of a photocatalyst (titanium dioxide) improved the removal efficiency of SDS substantially. The data generated in this work indicates that using UV-C LEDs in a UV/H2O2 reactor works, and the process was significantly more efficient than only UV radiation. The ease of handling the diodes and implementing them into the reactor offers a significant advantage over other light sources. The standard SDS determination method is known to be very time-consuming. Therefore, a new approach was developed. This technique works faster than the commonly used one and has a low standard deviation. Photodecomposition of the investigated impurity is possible. In the future, development will concentrate on the realisation and system integration of UV/H2O2 reactors, as a common technology in the product family of OPHARDT Hygiene AG.}, language = {en} } @misc{OPUS4-1655, title = {1/2023 Beiratsordnung f{\"u}r den Beirat des Bachelorstudiengangs International Business and Management an der Fakult{\"a}t Gesellschaft und {\"O}konomie der Hochschule Rhein-Waal vom 01.12.2022}, volume = {2023}, number = {01}, organization = {Hochschule Rhein-Waal}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-16551}, pages = {6}, language = {de} } @masterthesis{Hawas, type = {Bachelor Thesis}, author = {Hawas, Takwa}, title = {Chancen und Risiken der CAR-T-Zellen in der onkologischen Immuntherapie}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-16513}, school = {Hochschule Rhein-Waal}, pages = {75}, abstract = {Bei der CAR-T-Zell-Therapie erhalten Patient*innen nach einer Leukapherese autologer T-Lymphozyten ihre eigenen T-Zellen zur{\"u}ck, die vor der Behandlung mittels viraler Vektoren die chim{\"a}ren Antigenrezeptoren, engl. Chimeric Antigen Receptor (CAR), transduziert bekommen. Bereits Stunden nach der Zellinfusion und in den folgenden Wochen expandieren die CAR-T-Zellen und sind in der Lage, das Antigen spezifisch zu binden und die Tumorzellen zu zerst{\"o}ren. CAR-T-Zellen haben sich in Therapien gegen h{\"a}matologische Tumore als spektakul{\"a}r wirksam erwiesen. Doch die vielversprechende Behandlung hat ihre Grenzen und ihren Preis. Drei große Herausforderungen begrenzen derzeit ihren Erfolg im Bereich solider Tumore: Antigenerkennung, Migration und {\"U}berleben in der Tumormikroumgebung. CAR-T-Zell-Therapien z{\"a}hlen auch mit Kosten von etwa 300 Tausend Euro immer noch zu den teuersten Verfahren in der Medizin. Eine intensivere Forschung im Bereich der Dysfunktion des Immunsystems in der Tumormikroumgebung stellt ein notwendiger Schritt zur {\"U}berwindung von H{\"u}rden bei der Behandlung von soliden Tumoren mit CAR-T-Zellen dar. Angemessene finanzielle sowie gesetzliche Anreize und die Einf{\"u}hrung optimierter Herstellungsprozesse, multidisziplin{\"a}rer und pr{\"a}diktiver Ans{\"a}tze und zeitgem{\"a}ßer Tools der Biotechnologie und Bioinformatik in den klinischen Alltag zur pr{\"a}diktiven Krebsmodellierung sind ebenso wichtige Grundvoraussetzungen f{\"u}r eine wirtschaftliche Ausweitung des Einsatzes von CAR-T-Zellen. Anderenfalls w{\"u}rden Gesundheitssysteme die Kosten sowie die Komplexit{\"a}t nicht mehr stemmen k{\"o}nnen und diese lebensrettende CAR-T-Zell-Therapien w{\"u}rden außerhalb der Reichweite der Patienten bleiben, die es wirklich brauchen.}, language = {de} } @masterthesis{Murugesu, type = {Bachelor Thesis}, author = {Murugesu, Patmanjalie N}, title = {Production and Characterization of Polyhydroxyalkanoate Bioplastic from Palm Sludge Oil}, school = {Hochschule Rhein-Waal}, abstract = {The use of plastics has skyrocketed since its discovery in the 1900s and it can now be seen everywhere across the globe being used for many domestic as well as industrial applications. The overuse along with the unwise behaviour of discarding this material has caused negative impacts to the environment such as degradation of ecosystem affecting the flora and fauna of the Earth as well as giving rise to heavily fluctuating climatic conditions. As an attempt to combat the undesired outcomes from the use of these commodity plastics, many researches were devoted to the development of bioplastics made from natural resources that are fully biodegradable. Polyhydroxyalkanoate (PHA), a type of biodegradable bioplastic that possesses many types of monomers has gained the limelight due to its ability to be accumulated naturally in various different microorganisms under certain nutrient limiting conditions. In particular, the copolymer of this PHA, Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate), P(3HB-co-3HHx), has been studied vigorously due to its prominent resemblance to the commodity plastic on the basis of physical and mechanical properties. Nevertheless, the production of this copolymer was bottlenecked by the high cost of production in which most of it is contributed by the cost of carbon source used. Therefore, many researches were performed in testing cheap and renewable resource especially oilbased material as it has been reported to result in high yields of this PHA synthesized. This study focuses on the use of a by-product of the palm oil industry, which is the palm sludge oil (PSO) in the making of this PHA copolymer using a recombinant strain of Cupriavidus necator; a natural producer of this polymer. In addition to that, monomeric and physical characterisation of the PHA synthesized was performed in order to assess the PHA bioplastic produced from this possible feedstock.}, language = {en} } @masterthesis{Hartmann, type = {Bachelor Thesis}, author = {Hartmann, Tabea}, title = {Die Erforschung von potenziellen Zusammenh{\"a}ngen zwischen sozialer Neugier und der Gr{\"o}ße der sozialen Netzwerke von Studierenden zu Beginn des Studiums}, school = {Hochschule Rhein-Waal}, abstract = {Aufbau und Erhalt von sozialen Beziehungen finden {\"u}ber das gesamte Leben hinweg statt. In manchen Lebensphasen werden vermehrt soziale Kontakte gekn{\"u}pft. Ein solcher Abschnitt ist oft der Beginn eines Studiums. Hier vergr{\"o}ßert sich in der Regel das soziale Netzwerk. Wie viele neue Beziehungen aufgenommen werden, wird unter anderem von der Pers{\"o}nlichkeit der jeweiligen Person bestimmt. Um den Einfluss von sozialer Neugier auf die Gr{\"o}ße von sozialen Netzwerken zu {\"u}berpr{\"u}fen, wurden die Daten der Network Evaluation for Academic Retention - Studie ausgewertet. Die Studie erhebt unter anderem Daten zur Pers{\"o}nlichkeit und {\"u}ber egozentrierte Netzwerke von Erstsemesterstudierenden. Die Befragung erfolgt {\"u}ber einen Zeitraum von sechs Monaten zu drei konkreten Messzeitpunkten. Der Einfluss von sozialer Neugier auf die Gr{\"o}ße des gesamten sozialen Netzwerks und des nicht-famili{\"a}ren Netzwerks wurde mithilfe von multiplen Regressionsanalysen untersucht (N = 93). Es konnte kein signifikanter Zusammenhang gefunden werden. Auch die Analyse des Effekts der sozialen Neugier auf die Ver{\"a}nderung der Netzwerkgr{\"o}ße {\"u}ber sechs Monate ergab keine signifikanten Ergebnisse (n = 55). Bei den Analysen wurden auch andere Pers{\"o}nlichkeitsvariablen betrachtet, die in der Forschung bereits signifikante Zusammenh{\"a}nge mit der Gr{\"o}ße von sozialen Netzwerken aufgewiesen haben. In der verwendeten Stichprobe konnten diese Zusammenh{\"a}nge nicht verifiziert werden. Die Gr{\"u}nde f{\"u}r diesen Unterschied werden diskutiert. Die Untersuchung bietet einen ersten Einblick in den Zusammenhang von sozialer Neugier und der Gr{\"o}ße von sozialen Netzwerken, welcher in der Zukunft weiter erforscht werden sollte.}, language = {de} } @masterthesis{BarbosaSilva, type = {Bachelor Thesis}, author = {Barbosa Silva, Maria Eduarda}, title = {Motivation and Quality Management towards ISO 9001:2015}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-16453}, school = {Hochschule Rhein-Waal}, pages = {48}, abstract = {This bachelor thesis simulates a self-created schematic representation of the elements of a single process in ISO 9001:2015 (officially named as DIN EN ISO 9001:2015), incrementing problem-based aspects regarding employee management and motivation. Methodically, this paper provides a qualitative analysis, demonstrating theoretical and empirical findings in motivational methodologies and quality management. Motivation is a term that reduces itself into a diversifiable definition but is mostly associated to an individual's behavior to achieve goals. Work motivation theories follow different theories to explain the individual's behavior. These theories generate ideas to increase company performance, create goal-achievement, and can be achieved by managers mostly with extrinsic facets. On the other hand, within the DIN EN ISO 9001:2015 quality management system, work quality is divided into four focus areas: process orientation, management with motivational aspects, employee-, and customer satisfaction. Including, DIN EN ISO 9001:2015 is model oriented on a personal management basis. On behalf of the increasing employee-focus in DIN EN ISO 9001:2015, the German Society for Quality (Deutsche Gesellschaft f{\"u}r Qualit{\"a}t) proposes a New-Work model that emphasizes intrinsic motivation in the updated quality management process of DIN EN ISO 9001:2015. As a result of these theoretical findings, this thesis creates its own self-developed problem-based schematic representation of the elements of a single process in DIN EN ISO 9001:2015. Hereby, the current issues of quality management and motivation such as lack of quality awareness or limited motivation impulses in companies using DIN EN ISO 9001:2015 are emphasized and improved in the problem- based model. Quality management and motivation are progressively englobed as one factor in the current and future managerial models, which reinforces the importance of finding a problem-oriented solution.}, language = {en} } @masterthesis{Oesterwind, type = {Bachelor Thesis}, author = {Oesterwind, Ferdinand Clemens}, title = {Study on the Potential of Mob Grazing on Animal and Pasture Performance exemplified by an Organic Holstein Dairy Herd}, school = {Hochschule Rhein-Waal}, abstract = {Increasing adverse effects of climate change challenge Central European farmers. Severe precipitation deficits reduce fodder crop yields in livestock production and make grazing difficult. Understanding the effects of climate change and the impact grazing systems have on the environment is vital to economically utilize grassland. Mob grazing is a strategy that could provide an opportunity to ensure stable grassland yields during drought periods. Commonly used grazing systems, impact of climate change on pasture management and possible benefits of mob grazing are reviewed in this thesis. In addition, the effects of mob grazing on animal and pasture performance exemplified by an organic Holstein dairy herd are assessed in a field trial carried out at the Agricultural Chamber of North-Rhine Westphalia. The potential on animal performance is evaluated by milk yield and body condition. Pasture performance is determined by yield, sward height, pasture residues, and yield shares. Computation of milk yield from pasture allows for an interpretation of the potential of mob grazing in an interdisciplinary scope of pasture and animal performance. The research showed that mob grazing has the potential to achieve promising yields, regarding milk yield, pasture forage yield and milk production from pasture in comparison to conventional grazing systems. Mob grazing can provide resilience against potential consequences of climate change. It has the potential to be further adapted by farmers due to its economic and ecological advantages. To emphasize this, future research must focus on the effects of mob grazing on soil fertility, carbon sequestration and biodiversity.}, language = {en} } @misc{OPUS4-1642, title = {12/2022 Erste {\"A}nderungssatzung zur Praktikumsordnung f{\"u}r den Bachelorstudiengang Kindheitsp{\"a}dagogik der Fakult{\"a}t Gesellschaft und {\"O}konomie an der Hochschule Rhein-Waal vom 19.05.2022}, volume = {2022}, number = {12}, organization = {Hochschule Rhein-Waal}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-16426}, pages = {4}, language = {de} } @misc{OPUS4-1641, title = {11/2022 Zweite {\"A}nderungssatzung zur Pr{\"u}fungsordnung f{\"u}r den Bachelorstudiengang Kindheitsp{\"a}dagogik der Fakult{\"a}t Gesellschaft und {\"O}konomie an der Hochschule Rhein-Waal vom 18.05.2022}, volume = {2022}, number = {11}, organization = {Hochschule Rhein-Waal}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-16418}, pages = {3}, language = {de} } @masterthesis{Birkenbach, type = {Bachelor Thesis}, author = {Birkenbach, Gesa}, title = {Quantitative real-time PCR Detection of Yersinia ruckeri for Application in Aquaculture}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-16361}, school = {Hochschule Rhein-Waal}, pages = {76}, abstract = {To detect pathogen infections in aquaculture early and reduce their impact, a photonic biosensing chip is being developed in the PHOTO-SENS project, to enable fast and easy routine testing in aquaculture facilities. One target bacterial pathogen is Yersinia ruckeri, the causative agent of enteric redmouth disease. Detection is based on short DNA sequences (probes), that are complementary to the DNA of their target pathogen. In this work, a Yersinia ruckeri-specific probe was designed together with a set of qPCR primers. The probe and primers were tested in qPCR experiments, including quantifi- cation of extracted DNA, specificity and sensitivity testing, and detection of bacterial DNA from highly diluted samples to mimic the detection of environmental DNA. Three different standard series were created for the quantification of unknown samples. The influence of fish tissue on detection was tested, and the efficiency of Chelex-DNA ex- tractions were compared to peqGOLD Tissue DNA Mini Kit extractions. During quantification experiments with a first standard series (Y1P), the quantification output of most samples was 12-175 times higher than expected. The lower limit of detection was at 100 copies based on that standard, with an efficiency of 88\%. The discrepancy was reduced with a gBlocks standard (limit of detection: 5 copies; effi- ciency: 92\%). A CFU standard provided quantification results in reasonable agreement with expected CFU starting quantities (limit of detection: 1 CFU; efficiency: 106\%). De- tection of diluted samples after filtration was possible. Chelex DNA extractions yielded higher amounts of detectable DNA compared to a DNA extraction kit. Less bacterial DNA was extracted in bacterial culture samples containing fish tissue than in samples that did not contain fish tissue. Higher-than-expected quantification outputs were attributed to flaws in the creation of a first standard series as well as detectable DNA from dead cells or clusters that were not accounted for in the expected starting quantities. The gBlocks standard was as- sumed to be most reliable for quantification of exact copy numbers, while the CFU standard produced results that could be accounted for in CFU counts. As these chal- lenges concerned the standard series' and not the probe itself, it was concluded that the probe was suitable for application in the PHOTO-SENS project for detection of Yersinia ruckeri.}, language = {en} } @masterthesis{Meyer, type = {Bachelor Thesis}, author = {Meyer, Tobias}, title = {Automatisierte Tests oberfl{\"a}chenbezogener Gesch{\"a}ftslogik mit simulierten Benutzereingaben}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-8544}, school = {Hochschule Rhein-Waal}, pages = {64}, abstract = {A lack of stability and reliability in user interfaces leads to user dissatisfaction. If this dissatisfaction is a repeating occurence users loose trust in the software and the company behind it. In the long run this leads to a migration from existing users to competitors and less new customers. To combat these effects companies have to ensure their user interfaces are stable and reliable. The Schleupen AG provides a browserbased user interface to its customers, which is split into a display layer running in the browser and a logic layer running on the server. In this thesis an automated solution for finding such problems in the logic layer was developed and applied to a selected subset of user interfaces. The solution was able to find multiple issues with most of them representing possible stability problems. This showed that automated testing of user interfaces for stability and reliability is possible and worthwhile.}, language = {de} } @misc{Mou, type = {Master Thesis}, author = {Mou, Youness}, title = {A Hybrid Strategy Using Human Centered Design and Agile Methodologies to Develop an Error Taxonomy to Assist Businesses in Avoiding and Repairing Software Issues}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-16355}, school = {Hochschule Rhein-Waal}, pages = {178}, abstract = {Companies often utilize error taxonomies to handle software problems. Agile and scrum-based software engineering procedures leverage software testing and quality management to find, repair, and prevent functional faults. Taxonomies help programmers see patterns and solve comparable challenges. Usability engineering-based taxonomies emphasize the use of HCD approaches to discover and classify usability concerns across the software development life cycle. Software and usability engineering have pros and cons. This thesis presents a hybrid software challenge taxonomy to bridge these two areas. The research project aims to build a new hybrid error classification system for identifying and correcting software errors at their source, leading to more user-centric software. Software engineering taxonomies and design issues are investigated. The weaknesses of any research taxonomy are then evaluated against one that fits some of this thesis' needs. User interviews and contextual inquiry are used to uncover software faults. The results of the study showed that poor usability, a mediocre user interface, workflow issues, and poor user experience caused most non-technical problems. Non-functional faults may have created many technical challenges. Six out of ten company professionals who participated in a questionnaire and interview mistook "usability" for "user experience." Usability and user experience were valued by two out of ten specialists, but they were misunderstood, expensive, and time-consuming premium approaches, and thus not included in the software development lifecycle. Ignoring non-functional issues may have caused numerous software failures. Scrum and agile used alone may also be to blame for many of the software issues uncovered in this thesis project.}, language = {en} } @misc{Adebiyi, type = {Master Thesis}, author = {Adebiyi, Akinloluwa Iyanu}, title = {Combining User Experience Design \& Service Design: Theory meets Practice}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-16337}, school = {Hochschule Rhein-Waal}, pages = {94}, abstract = {This thesis explores how UXD and SD can work together more seamlessly in practice. UXD and SD have a lot of similarities. This has led to confusion around the borders and overlaps of both fields. Therefore researchers called for more studies to clarify their relationship. Most recent studies suggested diverting from polishing single touchpoints; some studies and focussing on end-to-end journey and the customer. The thesis examines the underlying activities of existing theoretical approaches and the challenges of combining UXD and SD with the help of thematic analysis. A set of proposed strategies were developed based on a survey on current practices and challenges with practitioners and thematic analysis. As a result, the thesis presents four strategies that design teams can incorporate into their processes. The idea is to promote the creation of better quality products and services by harnessing the benefits of both fields. The key point was that these concepts are still broad and should be simplified into leaner modes that can be applied in daily activities.}, language = {en} } @masterthesis{Kanwal, type = {Bachelor Thesis}, author = {Kanwal, Hafsa}, title = {Detection of the Fish Pathogen Vagococcus salmoninarum via Quantitative real-time PCR for Aquaculture}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-16222}, school = {Hochschule Rhein-Waal}, pages = {72}, abstract = {PHOTO-SENS is a project that aims to develop photonic biosensing chips as a means of allowing onset detection of pathogenic infections in aquaculture. These chips are meant to be a way for quick and simple routine testing that would enable aquaculture facilities to recognize potential outbreaks and minimize their effects. The chips detect target bacteria using short DNA sequences known as probes which are complementary to target DNA. One of the fish pathogens under consideration for the course of this project is Vagococcus salmoninarum, that is a causative agent of Vagococcosis. For this work, a primer and probe set specific to V. salmoninarum was designed. These primers and probes were then tested via qPCR for their selectivity and sensitivity and most importantly, quantification of DNA in samples using two different standard dilution series. Due to V. salmoninarum being a Gram-positive bacteria, three methods of DNA extraction were used and compared for maximum efficiency. Moreover, experiments were also conducted to mimic capture of eDNA (environmental DNA) from highly diluted water samples. Upon comparing the three DNA extraction methods, the improved 5\% Chelex protocol that included rapid agitation via glass beads, yielded the highest amount of DNA that was closest to expected SQ. The detection of all samples, including very low copy number, was possible via qPCR. The first standard series which was the gBlocks standard series had the lowest detection limit of 1 copy with an efficiency of 105.8\% and the second standard series that is the CFU standard series had a detection limit of 10 copies and had an efficiency of 104.2\%. The filtration experiment also showed detection in diluted, filtered samples. Since detection using the designed probe was successful, the probes are therefore considered suitable for detection of Vagococcus salmoninarum in the PHOTO-SENS project.}, language = {en} } @misc{Zenger, type = {Master Thesis}, author = {Zenger, Colin}, title = {Evaluation of functional silphie paper in the disposal process}, school = {Hochschule Rhein-Waal}, abstract = {The future of packaging seems to be in paper. Especially functional papers are on the rise of replacing plastic packaging more and more. The aim of the present work is to answer which disposal route is most suitable for functional silphie papers and how different coating techniques perform in a recyclability analysis. To answer this question, a laboratory experiment conducted in a paper laboratory in Lenningen, Germany tested how functional coating behaves in material recycling. Following the test method PTS-RH 021/2012 (Draft Ocober 2019), five functional paper samples and three reference samples with at least 35 \% silphie content were defibered and new laboratory sheets were formed. For this, water-based coatings and extrusion coatings were used as coating techniques. Additionally, the rejects were separated in a screening step and evaluated. The laboratory trials reveal important trends:. First, it shows that extrusion coatings detach from the paper surface and were found in the reject, from which they can be energetically recovered. This leads to a high mass loss and therefore a low recyclability rate. Second, for water-based coatings, solubility is of great importance. Results demonstrate that with good solubility, these coatings can lead to low mass loss and high recycling quality. Subsequently, this results in high recyclability rates. However, in samples with a difficult to dissolve water based coating, stickies and inhomogenities remained in the paper. This can significantly impede the recycling process. Future research could investigate further technologies of functionalization of silphie paper, as well as broaden the discussion by including complete mass balancing without loss of fibers and process water analysis. With the results obtained, OutNature is advised to pursue the route of water-based coatings while maintaining watch-out of their dissolvability in the recycling process. Extrusion coated functionality is to be avoided currently as the loss of mass for recycling is hindering recyclability with the current definitions and analysis methods. At the same time, reevaluation should be done if major changes in legislation or focus of discussion are happening.}, subject = {Recyclability}, language = {en} } @masterthesis{Karssli, type = {Bachelor Thesis}, author = {Karssli, Mahmoud}, title = {CRISPR technology in human medicine: advantages and disadvantages over traditional treatments}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-16080}, school = {Hochschule Rhein-Waal}, pages = {88}, abstract = {Genome editing tools hold tremendous potential in fighting various diseases via editing specific sites within the target gene of interest of distinct cell types. Among these tools, CRISPR has shown several advantages over alternative nucleases, such as ease of design, high efficiency, and low cost. In this work, a comprehensive review of the existing research on the application of CRISPR technology to the treatment of human diseases is presented. These diseases include monogenic and infectious diseases, as well as conditions for which immunotherapies are typically applied, such as cancer and autoimmune disorders. Following this review is an analysis of the advantages and disadvantages of CRISPR-based strategies compared to traditional treatments in a selection of diseases; this aims to demonstrate the overall potential of CRISPR therapeutic applications in humans and the need for further investigation and development.}, language = {en} } @masterthesis{Oezkoek, type = {Bachelor Thesis}, author = {{\"O}zk{\"o}k, G{\"u}l}, title = {Molekularbiologische Untersuchungen von Vibrio spp. auf das Vorhandensein von mobilen mcr-Genen und deren Klassifizierung}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-16148}, school = {Hochschule Rhein-Waal}, pages = {79}, abstract = {Vibrio spp. sind gramnegative Bakterien, die {\"u}berwiegend in aquatischen und marinen Lebensr{\"a}umen vorkommen. Sie umfassen >139 Spezies, von denen 12 Spezies als humanpathogen gelten. Diese unterschiedlichen pathogenen Spezies verursachen verschiedene Erkrankungen und sind vom Tier auf den Menschen {\"u}bertragbar. Durch den Einsatz von Antibiotika steigt die Anzahl resistenter Bakterien rasant an. Im Jahr 2015 wurde erstmals ein Colistin-Resistenz-vermittelndes mcr-1 Gen in einem E. coli identifiziert. Seither wurden r{\"u}ckblickend viele Isolate ermittelt, die mcr-Gene tragen (mcr-1 bis mcr-10). Seit 2016 gilt Colistin als „Critically Important Antimicrobial" und dient als „Last Resort Antibiotica", daher ist die Bewertung von mcr-Genen sehr bedeutsam. Ziel dieser Untersuchung war es, 67 Vibrio-Isolate auf das Vorhandensein von mcr-Genen zu untersuchen. Zu Beginn erfolgte eine Speziesidentifikation der Isolate mit Hilfe der MALDI-TOF MS und eine MHK-Analyse, um die MHK-Werte gegen{\"u}ber Colistin zu ermitteln. Anschließend wurden die Isolate f{\"u}r die MiSeq-Sequenzierung vorbereitet. Dazu z{\"a}hlten die Verfahren der DNA-Extraktion und der Library Preparation, wobei in mehreren Schritten die Konzentrationen der DNA mittels Qubit und die DNA-L{\"a}ngen mit dem LabChip gemessen wurden. Nach der Sequenzierung folgte die bioinformatische Auswertung, durch die unter anderem die Sequenzauswertung, die Speziesidentifikation und die Auswertung von Resistenzgenen erfolgte. Im Rahmen dieser Arbeit konnte ein Vibrio-Isolat mit einem mcr-Gen identifiziert werden; dieses trug zus{\"a}tzlich die Resistenzgene almG, eptA, lpxN und gspIEF. Es handelt sich um ein mcr-4 Gen in einem Plasmid, welches bisher nicht beschrieben ist. Das Plasmid tr{\"a}gt katalytische Dom{\"a}nen von Mobilit{\"a}ts-Genen, die weder durch die NCBI-Datenbank noch durch andere Tools detektiert werden konnten. Folglich kann keine Risikoabsch{\"a}tzung bez{\"u}glich der Transferabilit{\"a}t des Plasmids erfolgen. Zus{\"a}tzlich zu diesem Ergebnis konnten putative neue chromosomale Resistenzgene ermittelt werden, die eine hohe {\"A}hnlichkeit zu den bisher bekannten mcr-Genen aufweisen. Eine weiterf{\"u}hrende Analyse hinsichtlich des unbekannten Plasmids und der m{\"o}glichen neuen Resistenzgene erfolgt.}, language = {de} } @misc{Maier, type = {Master Thesis}, author = {Maier, Franziska}, title = {Komparative Analyse von Literaturdaten und Herstellerangaben zur Effektivit{\"a}t antimikrobiell ausger{\"u}steter Oberfl{\"a}chen}, school = {Hochschule Rhein-Waal}, abstract = {Die schnelle Ausbreitung von Mikroorganismen wie Bakterien, Pilzen und Viren kann {\"a}ußerst sch{\"a}dlich sein und zu saisonalen Epidemien f{\"u}hren. Dar{\"u}ber hinaus k{\"o}nnen diese Mikroorganismen Lebensmittel und wichtige Materialien verunreinigen, was zu erheblichen wirtschaftlichen Verlusten f{\"u}hrt. Um die Ausbreitung von Mikroorganismen zu verhindern, ist es wichtig, die Wechselwirkungen zwischen verschiedenen Mikroben und Oberfl{\"a}chen zu verstehen, die zu deren Anhaftung und Wachstum f{\"u}hren. Ein solches Verst{\"a}ndnis ist entscheidend f{\"u}r die Entwicklung antimikrobieller Oberfl{\"a}chen. In dieser Arbeit werden verschiedene Ans{\"a}tze und Produkte zu den antimikrobiellen Oberfl{\"a}chen untersucht und Oberfl{\"a}cheneigenschaften mit antimikrobiellen Aktivit{\"a}ten in Beziehung gebracht und analysiert. Eine Gegen{\"u}berstellung der wichtigsten Hersteller von antimikrobiellen Oberfl{\"a}chen und deren Technologien wird durchgef{\"u}hrt und mit aktuellen wissenschaftlichen Studien belegt. Die {\"U}bersicht konzentriert sich auf die physikalische und chemische Modifizierung der Oberfl{\"a}chen, um die Benetzbarkeit, die Oberfl{\"a}chentopografie und die Oberfl{\"a}chenladung zu modulieren und so die Adh{\"a}sion, das Wachstum und die Vermehrung von Mikroben zu hemmen. Dar{\"u}ber hinaus werden die Anwendungsgebiete von antimikrobiellen Oberfl{\"a}chen dargestellt. Die allgemeinen Erwartungen an eine antimikrobielle Oberfl{\"a}che sind hoch, da sie die Anhaftung und das Wachstum von pathogenen Mikroben wirksam verhindern und langlebig sind. Sie sollen sicher f{\"u}r Mensch und Umwelt und m{\"o}glichst kosteng{\"u}nstig sein. Bislang wurde das Design antimikrobieller Oberfl{\"a}chen zumeist nach dem Zufallsprinzip durchgef{\"u}hrt, ohne dass f{\"u}r jede Designstrategie robuste Struktur-Aktivit{\"a}ts-Beziehungen oder die beabsichtigte Verwendung eines bestimmten antimikrobiellen Materials ber{\"u}cksichtigt wurden. Dar{\"u}ber hinaus werden in der vorliegenden Arbeit die wichtigsten Erkenntnisse der Systeme zur Entwicklung antimikrobieller Oberfl{\"a}chen kritisch diskutiert, ebenso wie die Grenzen der aktuellen Forschung und die L{\"u}cke, die noch geschlossen werden muss, bevor diese Ans{\"a}tze in der Praxis umgesetzt werden k{\"o}nnen.}, language = {de} } @masterthesis{Takafakare, type = {Bachelor Thesis}, author = {Takafakare, Chiyedza}, title = {A critical assessment of the impact of an organization's affiliationtosocial movements on brand equity: A study of the Black Lives Matter Movement}, school = {Hochschule Rhein-Waal}, abstract = {Brands and advertising agencies have successfully tapped into the cultural momentum of social and political issues to attract new customers and promote their products. Numerous studies have examined the link between marketing and social and political movements, but advertising firms have largely ignored them. This study was titled "Acritical assessment of the impact of an organization's affiliation to social movements on brand equity: A study of the Black Lives Matter Movement". The study was guided by the objectives which were to identify the benefits of organizational allegiance to social movements on brand equity, determine the factors affecting social allegiance to social movements on brand equity, and recommend strategies that enhance brand equity. The study adopted a mixed methods approach whereby using a sample size of 65, online surveys were administered. Data was analyzed using descriptive means and SPSS was the main analysis tool. Findings illustrated that organizational allegiance to social movement has an impact on brandequity, profitability, and brand recognition. Brands are increasingly using social movements to promote their products, and much recent research has been done to understand what constitutes a socio-political activist brand, to explore consumers' attitudes, and determine if the perception of a brand as being socio-politically engaged has animpacton consumers' product use. When companies adopt a socio-political stance, they give consumers a far better opportunity to identify with them, while also allowing them to differentiate themselves from competitors by using secondary sources of meaning. Nonetheless, there are still untapped resources to be discovered, particularly in connection to the relationship between organizational allegiance and social movement participation.}, language = {en} } @masterthesis{Wagner, type = {Bachelor Thesis}, author = {Wagner, Katja}, title = {Einfluss der Versorgung von Coronapatienten auf die Pr{\"a}valenz und {\"U}bertragungsrate von multiresistenten Erregern}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-16029}, school = {Hochschule Rhein-Waal}, pages = {102}, abstract = {Einleitung: Das neuartige SARS-CoV-19 Virus hat weltweit zu einer Bedrohung der {\"o}ffentlichen Gesundheit gef{\"u}hrt. Nun stellen nicht nur die MRE in den Krankenh{\"a}usern ein Problem dar. Methoden: Es wurden die positiv getesteten SARS-CoV-2 Proben und die positiv getesteten MRE Proben retrospektiv vom 01.01.2018 bis zum 31.05.2022 ausgewertet. Mittels den Belegungszahlen wurden die Pr{\"a}valenzen der MRE berechnet. Die {\"U}bertragungsrate wurde anhand der nosokomialen F{\"a}lle berechnet. Die Jahre 2018 und 2019 stellen die Pr{\"a}valenz von MRE vor der COVID-19 Pandemie dar. Die Jahre 2020,2021 und 2022 (bis Mai) demonstrieren die Pr{\"a}valenz von MRE w{\"a}hrend der COVID-19 Pandemie. Ergebnisse: Die durchschnittliche MRSA Pr{\"a}valenz vor der COVID-19 Pandemie lag bei 0,66\%, w{\"a}hrend der Pandemie lag sie bei 0,52\%. Die durchschnittliche {\"U}bertragungsrate von MRSA lag vor der Pandemie bei 4,55\%, w{\"a}hrend der Pandemie lag sie bei 5,64\%. Die Pr{\"a}valenz von VRE lag im Schnitt vor der Pandemie bei 0,48\%, w{\"a}hrend der Pandemie lag sie bei 0,56\%. Die {\"U}bertragungsrate von VRE lag im Schnitt vor der Pandemie bei 57,98\%, w{\"a}hrend der Pandemie bei 52,79\%. Im Durchschnitt lag die 4MRGN Pr{\"a}valenz vor der Pandemie bei 0,04\% und w{\"a}hrend der Pandemie lag sie bei 0,06\%. Die {\"U}bertragungsrate von 4MRGN lag im Durchschnitt vor der Pandemie bei 43,47\% und w{\"a}hrend der Pandemie bei 17,29\%. Fazit: Die Pr{\"a}valenz von MRSA ist insgesamt gesunken, jedoch ist die {\"U}bertragungsrate von MRSA w{\"a}hrend der Pandemie gestiegen. Die Pr{\"a}valenz und {\"U}bertragungsrate von VRE verh{\"a}lt sich asynchron. Beim VRE ist die Pr{\"a}valenz gestiegen und die {\"U}bertragungsrate gesunken. Die Pr{\"a}valenz von 4MRGN hat w{\"a}hrend der Pandemie leicht zugenommen, w{\"a}hrend die {\"U}bertragungsrate stark zur{\"u}ckgegangen ist. Nach dieser Studie hat die Versorgung von Coronapatienten einen Einfluss auf die Pr{\"a}valenz und {\"U}bertragungsrate von MRE.}, language = {de} } @masterthesis{ViyofFul, type = {Bachelor Thesis}, author = {Viyof Ful, Flavian}, title = {The effects of P53 stabilitization in SMARCB1-deficent, deficent TP53- wildtype epitheliod sarcoma cells}, school = {Hochschule Rhein-Waal}, abstract = {Epithelioid sarcomas (ES) which are a rare form of soft tissue sarcomas are known to afflict both males and females with a slight bias for males. They are characterised by a defective SMARCB1 gene as well as a TP53 wildtype. Owing to this distinctive trait, it was hypothesised that reactivating p53 protein could hold therapeutic advantage in these type of tumours since p53 is a transcription factor at the crossroads between cell survival or death. P53 downstream target genes regulate the cell cycle or promote apoptosis. Since p53 is inactivated by its natural inhibitor, MDM2, in these types of tumours (Claudia Schaffner et al. 1999), using an MDM2 inhibitor to disrupt the P53-MDM2 interaction and stabilise p53 offered a sensible rationale to explore. It is often the case that cancer cells develop a resistance to a particular chemotherapy over time. Therefore, using a combination of two different inhibitors with completely different mechanisms of action to antagonise the tumour cells and prevent a possible recurrence was also considered. Two epithelioid sarcoma cell lines, VAESBJ and EPI544, were used for these experiments. HDM201, which is an MDM2 inhibitor, and doxorubicin, the current standard in threating epithelioid sarcomas, were both employed to be used as single agent treatments and in combination. Firstly, it had to be established that both cells are sensitive to the inhibitors in a dose dependent fashion. This was done using the MTS assay which quantifies cell viability based on the metabolism of tetrazolium salts and its eventual conversion to a purple soluble formazan residue by viable cells. Next, to further investigate the downstream effects of reactivated p53 in the cell populations, indirect immunofluorescence (IF) was performed to demonstrate that both inhibitors were capable of individually stabilising p53 in both cell lines. To further support the results from the indirect IF, western blot analysis was done to prove that p53 accumulates within the cell. Furthermore, quantitative polymerase chain reaction (PCR) was also performed to explore the extent to which p53's stabilisation influences the fate of the treated cells. The results obtained from the MTS assay experiments showed that the cell lines used were indeed sensitive to both inhibitors as single agent treatments (EPI544 cells IC50 (HDM)= 0.212nM, IC50 (Dox)= 259.9nM) and VAESBJ IC50 (HDM)= 1.52µM, IC50 (Dox)= 17.5nM). At their respective IC50 values in combination, both drugs acted synergistically to halt cell viability in VAESBJ cell line whereas they were antagonistic against EPI544 cell line. However, these discrepancies were due to the dose response of the cells to the drugs. Moreover, from the IF analysis, p53 was clearly stabilised and as a result affected cell viability in all cell lines for both drugs. There was a considerable amount of p53 accumulation in treated cells when analysed by western blot. Lastly, the qPCR data showed that upon stabilisation, p53 upregulated the cell cycle checkpoint protein p21 as well as its natural regulator MDM2 because of a negative feedback loop meant to regulate the amount of p53 in normal cells. BCL2 which encodes an anti-apoptotic protein is also downregulated in all treated cells. Pro-apoptotic TP53I3 gene is significantly upregulated in the cell populations treated with the combination. In a nutshell, the results support the rationale that targeting MDM2 in ES tumours holds therapeutic value. They also highlight the usefulness of combination therapies as a better approach at targeting cancer cells. Although p53 is stabilised, its accumulation and downstream effects are largely dependent on whether it was achieved through posttranslational modifications or not. These results necessitate future research to characterise the effects of a combination of HDM201 and Doxorubicin on ES tumours in vivo.}, language = {en} } @masterthesis{Ponten, type = {Bachelor Thesis}, author = {Ponten, Marvin}, title = {Visualisierung von Kulturg{\"u}tern am Beispiel der r{\"o}mischen Kaiserthermen in Trier als 3D Modell.}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-15889}, school = {Hochschule Rhein-Waal}, pages = {49}, abstract = {This paper is a summary of the "Kaiserthermen Project'' for the "Landesmuseum Trier" and shows in detail how to convert a 3Ds Max 3D model for usage into an open source program like Blender. It tries to explain the basics of 3D modelling and compares it to the 3D modelling of cultural heritages. It should work as a form of manual to further convert different models into the FBX file format. It also aims to explain the high value of cultural heritage as a 3D model and compares it to the 3D model of the "Trier Kaiserthermen". It furthermore gives examples and reasons for the usage of 3D models in different fields. It also presents the final 3D renderings and shows how they were created. At the end it explains how the perfect model for scientific research should be and how this project and paper improved this for the "Kaiserthermen".}, language = {de} } @masterthesis{Izzuddin, type = {Bachelor Thesis}, author = {Izzuddin, Kamal}, title = {Experimental and Simulative Study on the Performance of PEM Fuel Cell under Different Operating Conditions}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-15909}, school = {Hochschule Rhein-Waal}, pages = {80}, abstract = {The aim of the thesis is to study the influence of operating conditions on the performance of the proton exchange membrane fuel cell (PEMFC) such as temperature, cathode stoichiometry and cathode relative humidity. The experiment is conducted at temperature points of 60°C, 70°C and 80°C, where at each temperature point cathode stoichiometry of 2 and 5 are set. Within each stoichiometry, the cell is operated at cathode relative humidity of 50\%, 75\% and 100\%. The fuel cell performance is analyzed using two methods, current-voltage measurement, and the electrochemical impedance spectroscopy, where the polarization curves, power output density and high-frequency resistance (HFR) are recorded. A numerical analysis is then conducted on a 3-dimensional straight single channel fuel cell and is fitted with the data measured experimentally. Increasing the temperature has a different degree of improvement on the fuel cell's performance based on its cathode stoichiometry and relative humidity settings. The HFR measurements provide an insight into the voltage loss that is exerted by the fuel cell on each test condition. The numerical analysis shows that the impact of operating conditions does not exhibit any significant differences on the fuel cell model.}, language = {en} } @misc{Morawietz, type = {Master Thesis}, author = {Morawietz, Caroline}, title = {Etablierung von digitaler betrieblicher Gesundheitsf{\"o}rderung im Unternehmen anhand eines Praxisbeispiels im Handlungsfeld Ern{\"a}hrung}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-15938}, school = {Hochschule Rhein-Waal}, abstract = {Diese Masterarbeit skizziert die aktuelle Entwicklung der Digitalisierung im Bereich des Betrieblichen Gesundheitsmanagements (BGM) mit Fokus auf die Betriebliche Gesundheitsf{\"o}rderung (BGF) in Deutschland. Auf Grundlage von sieben Experteninterviews werden die Anforderungen f{\"u}r die langfristige Etablierung einer dBGF abgeleitet. Dabei werden die Rahmenbedingungen und Voraussetzungen f{\"u}r die Anbieter*innen im Bereich des BGM/BGF sowie f{\"u}r die Betriebe, die digitale BGF-Maßnahmen f{\"u}r ihre Mitarbeitenden einsetzen m{\"o}chten, ausgearbeitet und in der Struktur eines PDCA-Zyklus erl{\"a}utert. Anhand eines skizzierten Praxisbeispiels werden die Umsetzungsm{\"o}glichkeiten in digitalen BGF-Angeboten aufgezeigt. Das Praxisbeispiel skizziert ein Jahreskonzept im Handlungsfeld Ern{\"a}hrung, welches im Rahmen dieser Masterarbeit in Auftrag der Kraaibeek GmbH angepasst wurde. Die Masterarbeit soll folgende Fragestellungen beantworten: Wie kann eine digitale BGF nachhaltig in Unternehmen etabliert werden? Die Methodik besteht zum einen aus einer Literaturrecherche zum aktuellen Stand der digitalen BGF sowie den Voraussetzungen und Umsetzungsm{\"o}glichkeiten digitaler Maßnahmen im Bereich der BGF. Hierf{\"u}r wurden sieben leitfadengest{\"u}tzte Experteninterviews zur Beantwortung der Forschungsfrage, nach der qualitativen Inhaltsanalyse von Mayring, ausgewertet. Aus den Ergebnissen der qualitativen Inhaltsanalyse wurden Anforderungen f{\"u}r die Etablierung einer dBGF abgeleitet. Die Anforderungen sind grunds{\"a}tzlich auf den bereits bestehenden Anforderungen einer klassischen BGF aufzubauen, m{\"u}ssen jedoch um einige wesentliche ressourcenintensive Aspekte erg{\"a}nzt werden. Eine h{\"o}here Aufmerksamkeit erhalten die Faktoren: Kommunikation mit methodisch-didaktischen Ver{\"a}nderungen, Strukturierung und Bewerbung der Maßnahmen, Einbezug der F{\"u}hrungskr{\"a}fte, Datenschutzrichtlinien, technische Umsetzungsm{\"o}glichkeiten sowie die Aufkl{\"a}rung und der stetige Einbezug der Mitarbeitenden Die aus den Experteninterviews abgeleiteten Anforderungen wurden auf Grundlage eines PDCA Zyklus strukturiert dargestellt. Schlagw{\"o}rter: digitale Betriebliche Gesundheitsf{\"o}rderung (dBGF), digitale Betriebliches Gesundheitsmanagement, Gesundheitsf{\"o}rderung im Homeoffice, Digitale Gesundheitsf{\"o}rderung im Betrieb}, language = {de} } @masterthesis{Theiler, type = {Bachelor Thesis}, author = {Theiler, Jason}, title = {Implementierung und iterative Entwicklung eines Konzepts f{\"u}r eine Wissensduell-Applikation im Kontext von Serious Games}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-15988}, school = {Hochschule Rhein-Waal}, pages = {74}, abstract = {This bachelor thesis accompanies and documents the implementation and first step in the iterative development of a concept for a knowledge duel application. The application's goal is to exploit a player's playfulness and competitiveness, in order to learn new information and reinforce previously acquired knowledge. The concept was developed in cooperation with the B{\"a}umer, Afonso, Meissner GmbH. Because of its goal, the concept and its implementation are analyzed in the context of serious games. To achieve this, the thesis first examines the meaning of the serious games term and what their most significant attributes are. It also explores some state of the art systems and concepts of all the implementation's related fields. After extensive documentation of the concept and its implementation in the form of the web application called sw¨up, a formative evaluation using the results of several semi-structured interviews takes place. Following that, the thesis further explores possible improvements and new features for later iterations of the application. The evaluation shows that sw¨up happens to be a very intuitive, performant and both optically and structurally well designed application. Additionally several problem fixes and improvements were found while evaluating the interviews' results. While it is shown that sw¨up shares many similarities with a serious game, it can not be proven with the acquired results that sw¨up can effectively cause a learning effect and thus be considered a serious game. This remains to be determined by further, more in-depth tests and evaluations.}, language = {de} } @masterthesis{Sternberg, type = {Bachelor Thesis}, author = {Sternberg, Daniel}, title = {Cannabislegalisierung in Deutschland: Auswirkungen auf den Jugend- und Gesundheitsschutz}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-15970}, school = {Hochschule Rhein-Waal}, pages = {87}, abstract = {Das Thema der Cannabislegalisierung in Deutschland ist mit dem Beschluss im Koalitionsvertrag der neuen Koalition von 2021 so aktuell wie nie zuvor. In der vorliegenden Arbeit soll herausgearbeitet werden, ob die Cannabislegalisierung in Deutschland den Jugend- und Gesundheitsschutz f{\"o}rdern kann. Nach Beantwortung dieser Frage soll dar{\"u}ber hinaus analysiert werden, welche Maßnahmen bzw. Rahmenbedingungen der Legalisierung den Jugend- und Gesundheitsschutz am effektivsten f{\"o}rdern k{\"o}nnen. Zur Beantwortung dieser Forschungsfragen wurde eine umfassende Literaturrecherche durchgef{\"u}hrt. Dass Cannabis in Deutschland trotz Verbot konsumiert wird, zeigt die Lebenszeitpr{\"a}valenz von {\"u}ber 28 \%. Es wurde herausgestellt, dass Cannabis insbesondere f{\"u}r Jugendliche gesundheitliche Gefahren mit sich bringt. Auf Grund der Illegalit{\"a}t wird das Cannabis unkontrolliert auf dem Schwarzmarkt verkauft, weshalb es oftmals zu minderwertiger Qualit{\"a}t oder sogar Streckmitteln und Verunreinigungen kommt, die zus{\"a}tzliche Gesundheitsrisiken bergen. Ebenfalls wird der Kontakt zu anderen illegalen Drogen gef{\"o}rdert. Staaten, die Cannabis bereits legalisiert haben, zeigen, dass der Konsum kaum anstieg und bei Jugendlichen sogar r{\"u}ckl{\"a}ufig war. Bez{\"u}glich cannabisinduzierter Krankheiten konnte ein Anstieg festgestellt werden, der allerdings auf die steigende gesellschaftliche Akzeptanz von Cannabis zur{\"u}ckzuf{\"u}hren ist. Erstere Forschungsfrage l{\"a}sst sich demnach damit beantworten, dass mit dem Wegfallen versteckter Gefahren des Schwarzmarktes der Jugend- und Gesundheitsschutz gef{\"o}rdert werden kann, da das alleinige Verbot nicht vom Konsum abh{\"a}lt. Mit gewissen Rahmenbedingungen, wie z.B. dem Preis, Verkaufsstellen, H{\"o}chstabgabemengen, Produktion und THC-Obergrenzen kann die Gesundheit der Konsumenten gesch{\"u}tzt sowie auch die H{\"a}ufigkeit und Intensit{\"a}t des Konsums eingeschr{\"a}nkt werden. Somit sch{\"u}tzt die Legalisierung von Cannabis unter den richtigen Rahmenbedingungen effektiv die Gesundheit von Jugendlichen sowie allen Cannabiskonsumenten, w{\"a}hrend dar{\"u}ber hinaus finanzielle Vorteile entstehen.}, language = {de} } @masterthesis{Brender, type = {Bachelor Thesis}, author = {Brender, Nadja}, title = {Effects of Simulated Drought on Microbial Activity in Biologically and Conventionally managed Soils}, school = {Hochschule Rhein-Waal}, abstract = {Increasing droughts and intensified agricultural management cause stress and disturbance on agricultural soil, but their effects on soil microbial activity are not fully known yet. This thesis studied the effects of induced short-term drought in two contrasting agricultural management systems, namely biodynamic (BioDyn) and conventional (ConMin), on microbial activity. The soil samples taken from the DOK long-term trial were analysed using MicroResp™, fluorometric enzyme assays and disease suppression bioassays. Soil basal- and multiple substrate-induced respiration (MSIR), microbial functional diversity, extracellular enzymatic activity (EEA) and soil suppressiveness against Pythium ultimum (Pu) were evaluated as indicators for microbial activity. Drought increased basal respiration but had no effects on other parameters. Conventional farming decreased EEA involved in carbon (C)- and nitrogen (N)-cycling, while it increased phosphorus (P)-cycling. No significant effects on the interaction between farming system and drought were found. The results indicate that organic farming has, to some extent, positive effects on microbial activity while drought does not decrease activity but induces stress in microorganisms.}, language = {en} } @misc{Akbik, type = {Master Thesis}, author = {Akbik, Hia}, title = {The Effect of Risk and Uncertainity on Purchasing Decisions}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-15858}, school = {Hochschule Rhein-Waal}, pages = {95}, abstract = {The end of 2019 has brought upon the world a new virus called Covid-19 that has quickly evolved into a pandemic at the start of 2020. To control the spread of the virus, countries around the world were forced to implement various strict measures that includes travel bans, lockdowns, and limited social contacts. As per pervious pandemics, this crisis had severe consequences on economy, consumer behavior, purchasing decisions and people's mental and physical wellbeing. Consumers were forced to adapt and find alternatives that would fit the "new norm". This added to the psychological distress people were experi-encing and in turn increased their feeling of risk and uncertainty. Thus, this research con-ducts a semi-structured exploratory in-depth interview (N=16) to profoundly investigate the effect of risk and uncertainty on consumers' purchasing decisions in Germany. Find-ings of this study suggests that consumers with high uncertainty avoidance and high per-ceived risk are more likely to have a changed behavior. Their purchasing decisions are more oriented toward necessities and self-development products. On the other hand, con-sumers with low uncertainity avoidance and risk perception have experiences less change in terms of consumer behavior and purchasing decisions. The results of this research would help companies understand consumers' psychological needs which is often ne-glected in literature to provide the needed products and services. It would also benefit the academic and professional world by knowing what to expect during crisis and if changed behaviors will continue after the pandemic is over.}, language = {en} } @techreport{OPUS4-1579, title = {Days of Antidiscrimination 2 - 29. Nov-03. Dez 2021}, editor = {Zimenkova, Tatiana and Ascani, Katrin}, organization = {Hochschule Rhein-Waal}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-15792}, pages = {24}, abstract = {This digital brochure shows the results and impressions of the five-day event "Virtual Days of Antidiscrimination 2" at Rhine-Waal University of Applied Sciences, which took place from November 29 to December 3, 2021. The Vice-President for Internationalisation and Diversity and the AStA jointly organized this exchange of all university members and, with this report, make visible the voices of the participants, the expertise of the academics and activists and the contributions of the students.}, language = {en} } @masterthesis{Siamudaala, type = {Bachelor Thesis}, author = {Siamudaala, Nathan}, title = {Enhancing the Resilience of the Zambian Maize and Aquaculture Value Chains}, school = {Hochschule Rhein-Waal}, abstract = {Many Zambian people depend on Maize for their livelihoods and much of their nutrition. With the increase in the number of disruptions globally, much of the Zambian population is at risk of suffering from malnutrition. Also, the Maize bias has not assisted poverty reduction, especially in rural areas. In response, the Zambian government has urged farmers to diversify and invest in other agricultural sectors. One industry that has been of interest to the state is the aquaculture sector. This thesis aims to understand the resilience of Maize and aquaculture value chains to offer policy recommendations to decision-makers. To that end, this study utilizes a metric called the Farmers Adaptive Ratio, which looks at a loss in a food systems resilience after a disturbance occurs and a value chain resilience assessment questionnaire in order to understand reasons for or the lack of resilience. Results show that the Zambian Maize value chain is not resilient to the Fall Army Worm and Droughts. However, the disruptions do not affect all actors in the same way. For example, the study discovered that small-scale farmers are the most vulnerable to shocks. The aquaculture value chain displayed much higher resilience than the Maize value chain. The most significant disturbance is the volatile feed prices. The resilience of both value chains can be enhanced by employing long-term irrigation policies and investing in research and development to find local solutions to some of the disturbances.}, language = {en} } @misc{SilvaCabral, type = {Master Thesis}, author = {Silva Cabral, Catarina}, title = {Einfluss eines 10-w{\"o}chigen Kraft- und Ausdauertrainings auf Entz{\"u}ndungsbiomarker im Blut bei Menschen mit schubf{\"o}rmig remittierender Multipler Sklerose}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-15826}, school = {Hochschule Rhein-Waal}, abstract = {Hintergrund: Die Multiple Sklerose (MS) ist eine bis dato unheilbare chronisch-entz{\"u}ndliche Erkrankung des zentralen Nervensystems, bei der es zur Besch{\"a}digung und teilweise auch zur Zerst{\"o}rung der Myelinscheiden kommt. H{\"a}ufig wird die medikament{\"o}se Therapie eingesetzt, welche jedoch h{\"a}ufig mit unerw{\"u}nschten Nebenwirkungen verbunden ist. Sport wirkt, wie auch die medikament{\"o}se Therapie, nachweislich immunmodulatorisch. Dieser l{\"a}sst sich folglich in der symptomatischen Behandlung einsetzten und hilft, das Fortschreiten der Erkrankung zu kontrollieren. Erwiesenermaßen ruft regelm{\"a}ßige k{\"o}rperliche Bewegung ebenso entz{\"u}ndungshemmende Mechanismen hervor. Demzufolge birgt regem{\"a}ßiger Sport großes Potenzial in der Pr{\"a}vention und Behandlung von Krankheiten, die im Zusammenhang mit chronischen Entz{\"u}ndungen stehen. Ziel: Im Rahmen dieser Arbeit soll der Einfluss eines kombinierten Kraft- und Ausdauertrainings auf den Neutrophilen-Lymphozyten-Quotient (NLR), den Pl{\"a}ttchen-Lymphozyten-Quotient (PLR) und den systemischen Immuninflammationsindex (SII) bei Personen mit schubf{\"o}rmig remittierender Multipler Sklerose untersucht werden. In diesem Zusammenhang soll der akute und chronische Einfluss von Training auf die untersuchten Parameter beschrieben werden. Methoden: Vierzehn Personen mit eindeutig diagnostizierter RRMS wurden der Interventionsgruppe (n = 7) oder der Kontrollgruppe (n = 7) randomisiert zugeteilt. {\"U}ber einen Interventionszeitraum von zehn Wochen nahm die Interventionsgruppe dreimal w{\"o}chentlich an einem funktionellen Kraft- und Ausdauertraining teil, w{\"a}hrend die Kontrollgruppe keinem spezifischen Training nachging. Die Entz{\"u}ndungsmarker wurden aus den gewonnen Daten des Blutbildes bestimmt. Ergebnisse: Der Einfluss eines hochintensiven kombinierten Kraft- und Ausdauertrainings auf die NLR, PLR und den SII kann aufgrund eines nicht signifikanten Effektes in dieser Arbeit nicht best{\"a}tigt werden (NLR: p = 0,582; PLR: p = 0,940; SII: p = 0,225). Ebenso konnte kein signifikanter Unterschied zwischen dem akuten Effekt einer Trainingseinheit und dem chronischen Trainingseffekt nach zehn Wochen festgestellt werden (NLR: p = 0,243; PLR: p = 0,497; SII: p = 0,218). Fazit: Trotz der nicht signifikanten Ergebnisse bietet diese Untersuchung erste Hinweise zu der Auswirkungen von Sport auf MS-Patienten. Die bereits bestehende Evidenz zu potentiellen positiven Effekten durch k{\"o}rperliches Training auf den Entz{\"u}ndungsstatus von MS-Betroffenen ist heterogen. Daher besteht weiterhin Forschungsbedarf.}, language = {de} } @masterthesis{Kouis, type = {Bachelor Thesis}, author = {Kouis, Zacharias}, title = {Photovoltaic power potential in Cyprus and how the synergies observed in an Agrivoltaic system affect the efficiency of food and energy production}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-15707}, school = {Hochschule Rhein-Waal}, pages = {72}, abstract = {Cyprus plans to drastically increase its share of RES grid penetration from 16.7\% in 2020 to 22.9\% in 2030 by taking advantage of the sun's energy abundance in the region and the favorable climatic conditions available. In this study, the solar potential of Cyprus through PV technology will be assessed and quantified with the use of PVGIS tool on three different levels: theoretical, practical and economical, while spatial representation of the region's potential will allow for better comprehension of the concept. Land use constraints being a major limitation for the implementations of such concepts can be avoided with the dual use of land in a scheme known as Agrivoltaics. The coexistence of crop and energy production can give rise to synergies that affect the efficiency of such schemes. This paper using a qualitative approach will investigate and analyse these possible synergies and will identify barriers that might arouse. Results demonstrate yearly GHI and DNI values of 1963.62 kWh/m2 and 2201.61 kWh/m2 respectively, while yearly PVOUT accounts for 1828.75 kWh/kWp with a seasonality index of 1.4 and LCOE value of €0.053/kWh, evidencing undoubtedly the resource's potential in the region. Within an agrivoltaic system nine categories of synergies where identified indicating an overall positive effect in the efficiency of food-energy nexus. The limpid representation of the PV energy resource potential in Cyprus and the comprehensive description of the arousing synergies can propel further exploitation of the agrivoltaic concept within the region.}, language = {en} } @misc{Bhadula, type = {Master Thesis}, author = {Bhadula, Divya}, title = {Evaluating the influence of adaption to the vegan lifestyle on protecting the right of farm animals and challenges faced by them due to climate change}, school = {Hochschule Rhein-Waal}, abstract = {This research is on evaluating the influence of vegan lifestyle on the protection of animal rights. There are different factors that influence the adaption of veganism, such as ethical reasons or health reasons for choosing a vegan lifestyle. Those factors have been evaluated in this research in the context of European countries. There are different steps taken by the European countries to improve animal protection at livestock farms, which have also been determined in this research. The evaluation has identified that there are different initiatives taken by European countries and EFSA to ensure that the animals feel less pain and distress on livestock farms. Climate change also has an influence on animal protection. Specifically, it is related to the livestock farms as well because it impacts the quality of crop and water supply. It have been identified that both livestock farms and climate change have an influence on each other, and the steps are being taken to overcome the challenges related to the influence of climate change on livestock farms.}, language = {en} } @masterthesis{Islam, type = {Bachelor Thesis}, author = {Islam, Md Ariful}, title = {Effects of arbuscular mycorrhizal fungi on plant growth, yield, and plant-parasitic nematode control in organic tomato production: A field study and a systematic review}, school = {Hochschule Rhein-Waal}, abstract = {The symbiotic relationship between plants and Arbuscular Mycorrhizal fungi (AMF) is widely known. However, the effect of AMF on plant growth and overall yield, together with plant physiology and soil metabolism under inappropriate field conditions, shows ambiguous conclusions. Moreover, AMF in organic farming systems may be less effective because organic farming excludes most biocides and water-soluble fertilizers and generally have more diversified rotations. AMF can be used as a natural tool to reduce the effect of plant-parasitic nematodes (PPN) as well. Therefore, this study aims to assess the impact of AMF on plant growth, yield, and PPN in organic tomato production. The study consists of a field study and a systematic review. A renowned tomato variety and a mixture of AMF inoculum were used in an organic greenhouse with a controlled irrigation system for the field experiment. In addition, a Systematic Literature Review using the PRISMA framework was conducted to investigate the effect of AMF on the PPN population. For the simplicity of this review, PPN Pratylenchus spp. (PS) was only included, as AMF inoculated plants exhibit better tolerance under PS pressure. Results showed no significant increase in overall tomato production in response to AMF application. However, a positive correlation was found between AMF and PS population densities, as most studies indicated no effect or decrease in the PS population. Different AMF and PS interaction results indicate the involvement of different cultivars, soil characteristics, temperature, and various AMF and crop species. The mechanisms involved in these interactions are reviewed and could be an object for further study.}, language = {en} } @masterthesis{Mizane, type = {Bachelor Thesis}, author = {Mizane, Amal}, title = {Implementation of organic agriculture and sustainability thinking in higher agricultural education in Uganda}, school = {Hochschule Rhein-Waal}, abstract = {Several significant reforms have been implemented by the Ugandan government in the last few years aimed at converting conventional agriculture into organic agriculture. To analyze the impact of organic agriculture policies on the education system in Uganda, in this study, it has been assessed the number of courses, training institutions, and University programs available during the past years. The researcher also examined from the students' perspective the limitations and possible improvements of the organic agriculture courses to identify possible gaps and develop better strategies. Furthermore, the researcher interviewed students from Uganda Martyrs University, a leading African University in Agro-ecological solutions, with top-rated courses in Organic Agriculture and Agroecology. The research revealed there are several courses available in Uganda based on the policies found. Most programs are dealing with Agroecology and Organic agriculture.}, language = {en} } @masterthesis{Cheung, type = {Bachelor Thesis}, author = {Cheung, Ho Yu}, title = {Comparison of wheel and rubber track drives for tractors regarding masses, mass inertias, energy demands and tractor mechanics}, school = {Hochschule Rhein-Waal}, abstract = {Soil compaction is a major concern in agriculture. As farming machinery develops to be larger and heavier, the risk of soil compaction increases. Tractors with rubber tracks have been developed to increase the contact area with soil in order to reduce the risk of soil compaction as well as to increase tractive performance. However, tractors with rubber tracks have increased mass due to the track components. Therefore, the combined effect of rubber tracks was investigated. Comparison of tyres and rubber tracks for tractors on mass, mass inertia, tractor mechanics, energy demand, and soil compaction were investigated. Configurations of tractors consisting of combinations of tyres and interchangeable rubber tracks are evaluated in calculations and in simulation tool Terranimo. Simplified rubber track models were built in order to investigate effect of inertia from the rotational components on energy demand. A theoretical scenario was constructed to calculate the energy demand for the predefined workload. Experimental data in past research showed that the superior tractive performance of rubber track is more apparent in looser soil. In the energy demand calculation part of the thesis the tracked configurations resulted in a higher energy demand. The tracked configurations also showed effect on reducing risk of soil compaction in the same defined scenario. However, the increased energy demand, hence higher fuel consumption and energy efficiency is a downside of the tracked configurations, and the selection between tyre and rubber track should depend on the situation.}, language = {en} } @techreport{Guggenberger, type = {Working Paper}, author = {Guggenberger, Lennart}, title = {Die Befristung von Arbeitsverh{\"a}ltnissen in der Rechtsprechung des Bundesarbeitsgerichts}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-15671}, pages = {6}, abstract = {In diesem Arbeitspapier werden die Befristung von Arbeitsverh{\"a}ltnissen und aktuelle F{\"a}lle der Rechtsprechung er{\"o}rtert.}, language = {de} } @misc{Hoffmann, type = {Master Thesis}, author = {Hoffmann, Annika}, title = {Wie der Darm unsere Psyche beeinflusst-Modulation des Mikrobioms als geeigneter Therapieansatz f{\"u}r psychische Krankheiten?}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-15614}, school = {Hochschule Rhein-Waal}, abstract = {Die Pr{\"a}valenz von psychischen Erkrankungen ist in der Bev{\"o}lkerung weit verbreitet und in den letzten Jahren stark angestiegen. J{\"a}hrlich sind etwa 27,8 \% der Erwachsenen in Deutschland von psychischen Erkrankungen betroffen. Dabei sind die R{\"u}ckfallquoten und die Wahrscheinlichkeit einer Chronifizierung dieser Krankheiten sehr hoch. Auch besteht die Problematik, dass es wenige Anlaufstellen f{\"u}r die Betroffenen gibt, lange Wartezeiten in Kauf genommen werden m{\"u}ssen und herk{\"o}mmliche medikament{\"o}se Therapien teilweise starke Nebenwirkungen hervorrufen. In dieser Masterthesis wurde der Zusammenhang zwischen psychischen Krankheiten, dem Mikrobiom und Stoffwechselparametern untersucht, um zu kl{\"a}ren, ob eine Modulation des Darm Mikrobioms durch Pr{\"a}biotika und Probiotika einen geeigneten Behandlungsansatz f{\"u}r die Therapie von psychischen Erkrankungen wie Depressionen, Angstst{\"o}rungen, Schizophrenie oder Anorexia nervosa darstellen k{\"o}nnte. Dazu wurden insgesamt 55 Artikel analysiert. Die Abundanz von Darmmikroben auf Phylum-, Familien- und Gattungsebene, die Konzentrationsver{\"a}nderung von Stoffwechselparametern, die Auswirkungen bestimmter Mikroorganismen auf die Stoffwechselparameter und der Effekt von Pr{\"a}- und Probiotika auf das Mikrobiom und die Verhaltensweisen der Patienten bzw. der Tiere wurden in den Studien verglichen. Es konnte eine Korrelation zwischen der relativen H{\"a}ufigkeit bestimmter Mikroorganismen, den von ihnen produzierten Metaboliten und dem Auftreten der untersuchten psychischen Erkrankungen festgestellt werden. Durch die Supplementation mit Pr{\"a}- und Probiotika und insbesondere durch Lactobacillus spp. und Bifidobacterium spp., konnten die Symptome abgeschw{\"a}cht werden. Vor allem der kombinierte Einsatz von Pro- und Pr{\"a}biotika hat sich als effektiv erwiesen. Die Behandlung von psychischen Erkrankungen ausschließlich durch den Einsatz von Pr{\"a}- und Probiotika ist h{\"a}ufig nicht ausreichend. In Kombination mit herk{\"o}mmlichen Behandlungsmethoden ist die gezielte Modulation des Mikrobioms als sinnvoll zu bewerten. Insgesamt ist dieses Themenfeld jedoch noch wenig erforscht und die Literatur liefert teilweise widerspr{\"u}chliche Ergebnisse, wodurch zuk{\"u}nftig weitere Untersuchungen erforderlich sind.}, language = {de} } @masterthesis{Ruiz, type = {Bachelor Thesis}, author = {Ruiz, Yudit}, title = {Investigation of Self-Healing in Fruit Epidermis with Atomic Force Microscopy}, school = {Hochschule Rhein-Waal}, abstract = {Different advanced microscopy techniques, mainly atomic force microscopy and scanning electron microscopy are used to inspect damage healing on fruit epidermis using squash - Cucurbita pepo L. - as prime specimen. The approach and methods used followed instructions reported by comparable projects studying epicuticular wax regeneration with SEM and AFM. However, novel detailed and instructive information was collected and reported on how to perform tasks involving certain degrees of technical difficulty, such as using AFM to find a particular location on a sample that is, by definition, thousands of times larger than the target focal zone. A non-reported system was used to trace and cut out the damages on the fruit surface. The manipulation and lithography mode of the AFM JPK software is known to work to trace micro-scale designs on hard surfaces such as CDs but we prove it can also be used on soft and very irregular surfaces such as that of C. pepo - to a certain extent. A total of 19 scratches and one round-shaped damage were cut and optical information was collected through time with AFM. All relevant parameters were measured with the JPKs built-in measuring tool and information was collected and later plotted on excel spreadsheets. Damage sealing was found to happen for all cases and for almost all different parameters -length, depth, width. The characteristics of all cases reported are unique - follow up times vary from minutes to hours and other features such as initial damage size and the force applied for its creation are different. However, damage sealing did not seem to correlate with any of these. Samples cut from specimens several days after purchase or simply from specimens with a rough, dry surface seemed to progress much more slowly than those coming from fresh-looking samples. The focus of the study was the fruit cuticle (stiff polymeric film covering the outer surface of all higher plants). To make sure that the processes of healing observed actually correspond to this part a) wax was removed in all of the samples and b) the cuticle of our model fruit was measured with light microscopy, showing that its thickness is much higher than the deepest of our AFM scratches. This way we aimed to prove that the regeneration observed represents actual cellulose regrowth and cellular activity healing the cutin layer. Progress is observed in all cases, which is a good sign. However, wax is known to regenerate immediately after removal in experiments with leaves. The fact that some of our damages seal within the first 10 minutes of observation may be an indication that wax is filling the scratch instead of other biological activity. Further research is needed to clarify the nature of this process.}, language = {en} } @techreport{Peltzer, type = {Working Paper}, author = {Peltzer, Henrik}, title = {Die Befristung von Arbeitsverh{\"a}ltnissen in der Rechtsprechung des Bundesarbeitsgerichts}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-15582}, pages = {6}, abstract = {Die Befristung von Arbeitsverh{\"a}ltnissen in der Rechtsprechung des Bundesarbeitsgerichts - Hausarbeit f{\"u}r das Modul Grundlagen Recht}, language = {de} } @misc{Theiss, type = {Master Thesis}, author = {Theiss, Doreen Viktoria}, title = {Implementierung einer zielgerichteten Gesundheitsf{\"o}rderung im betrieblichen Gesundheitsmanagement mit einer deskriptiven Studie zur Human Ressource-gest{\"u}tzten Analyse eines Großunternehmens und Entwicklung bedarfsgerechter Gesundheitsf{\"o}rderungsmaßnahmen}, school = {Hochschule Rhein-Waal}, abstract = {Vor dem Hintergrund der wachsenden Bedeutung des Erhalts der Gesundheit und Besch{\"a}ftigungsf{\"a}higkeit Erwerbst{\"a}tiger wurde der Auftrag zur Implementierung einer betrieblichen Gesundheitsf{\"o}rderung (BGF) in einem Großunternehmen erteilt. Ziel der vorliegenden Abschlussarbeit ist es, Ziele f{\"u}r eine bedarfsgerechte BGF und einen Maßnahmenplan zu entwickeln. F{\"u}r eine bedarfsgerechte Ausrichtung muss die Ist-Situation im Unternehmen analysiert werden. Dazu wird folgende Forschungsfrage gestellt: Welche Rahmenbedingungen bestehen in dem untersuchten Großunternehmen und sind relevant bei der Entwicklung zielgerichteter betrieblicher Gesundheitsf{\"o}rderungsmaßnahmen? Um die Forschungsfrage zu beantworten, wird eine deskriptive Studie zur Sekund{\"a}r- und Prim{\"a}ranalyse des Großunternehmens durchgef{\"u}hrt. Hierf{\"u}r werden vorhandene Daten der Besch{\"a}ftigten analysiert und mittels eines Fragebogens neue Mitarbeiterdaten erhoben. Untersucht werden als Rahmenbedingungen der Ist-Zustand des betrieblichen Gesundheitsmanagements (BGM) im Unternehmen, die vorherrschende Arbeitsumgebung und die betriebsinternen Strukturen, der aktuelle (subjektive) Gesundheitszustand sowie bestehende Mitarbeiterbed{\"u}rfnisse bez{\"u}glich ihrer aktuellen gesundheitlichen Situation. In die Stichprobe einbezogen werden alle Mitarbeitenden an allen deutschen Standorten des Unternehmens, diese stellen die Zielgruppe der Gesundheitsf{\"o}rderungsmaßnahmen dar. Die Ergebnisse werden in St{\"a}rken und Schw{\"a}chen (interne Faktoren) sowie Chancen und Risiken (externe Faktoren) unterteilt und daraus strategische Stoßrichtungen entwickelt. Aus diesen werden lang- und kurzfristige (operative) Ziele entwickelt und Maßnahmen zur Erreichung dieser formuliert. Zur {\"U}berpr{\"u}fung der Zielerreichung werden Mess- und Zielgr{\"o}ßen f{\"u}r die operativen Ziele formuliert. Die quantitative Studie zeigt, dass ein {\"u}berdurchschnittlich schlechter Krankenstand, vielf{\"a}ltige Arbeitsbelastungen, eine geringe Arbeitsmotivation und -organisation und ein ausbauf{\"a}higes Betriebsklima im Unternehmen vorherrschen. Zudem gibt es ein BGM und eine BGF, welche f{\"u}r einen Erfolg {\"u}berarbeitet werden sollten. Es konnten vier strategische und, f{\"u}r diese, 33 operative Ziele sowie vielf{\"a}ltige Maßnahmen entwickelt werden. Durch diese Abschlussarbeit wird der Grundstein f{\"u}r die Implementierung einer bedarfsgerechten BGF gelegt, anhand dessen wesentliche Strukturen optimiert sowie konkrete Maßnahmen zur Umsetzung gebracht werden k{\"o}nnen. Die Arbeit gibt Orientierung bei der Weiterf{\"u}hrung der BGF als Regelkreis f{\"u}r das Großunternehmen, als auch f{\"u}r andere Unternehmen bei der Einf{\"u}hrung einer BGF und der Anwendung einer Mitarbeiterbefragung.}, subject = {Betriebliche Gesundheitsf{\"o}rderung}, language = {de} } @misc{OPUS4-1557, title = {10/2022 Rahmenordnung zur Gremienarbeit der nicht{\"o}ffentlich tagenden Gremien der Hochschule Rhein-Waal in elektronischer Kommunikation (Gremienordnung - GremienO) vom 07.06.2022}, volume = {2022}, number = {10}, organization = {Hochschule Rhein-Waal}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-15575}, pages = {6}, language = {de} } @techreport{Olgun, type = {Working Paper}, author = {Olgun, Ismail}, title = {{\"O}ffentlich-rechtliche Vertr{\"a}ge - Juristische Grundlagen, Sinn, Fallbeispiele}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-15569}, pages = {6}, abstract = {In diesem Arbeitspapier, das an der Fakult{\"a}t f{\"u}r Kommunikation und Umwelt der Hochschule Rhein-Waal entstanden ist, werden {\"o}ffentlich-rechtliche Vertr{\"a}ge hinsichtlich ihrer juristischen Grundlagen, ihres Sinnes und aktuellen Fallbeispielen er{\"o}rtert und mit genauen Quellenangaben versehen.}, language = {de} } @masterthesis{Nosseir, type = {Bachelor Thesis}, author = {Nosseir, Dominic}, title = {Prototypisches Design einer barrierefreien E-Commerce- Website - gem{\"a}ß der Web Content Accessibility Guidelines (WCAG) 2.1}, school = {Hochschule Rhein-Waal}, abstract = {This work focuses on accessibility on the internet, in this context a research for a prototype was developed and afterwards evaluated, to show the usability difference between an accessible and an inaccessible website. Both sites were evaluated with respectively three test subjects for every site, to find out which site is more user- friendly. For this purpose The Web Content Accessibility Guidelines (WCAG) were explained. Afterwards ten E-Commerce-Sites that sell Dog Food were analyzed on their conformity to the WCAG, to find the most common WCAG-violations, in order to prevent these in the later implementation of the prototype. This prototype was developed in three stages, the first one was a paper-prototype to concept the structure. The second was modeled through the software „Figma" to specify the styling. At the end the final prototype was implemented in HTML with the „Angular" framework. Thereafter, the prototype was examined through user-tests to check if there were usability-errors or inaccessible elements, that need to be fixed in order to accomplish an accessible prototype. After the result were evaluated and the found accessibility- errors were fixed. The prototype went again through a usability-test execution, to ensure that the prototype is accessible. The result show, that the accessible site is more user-friendly and WCAG compliant than the inaccessible site. So the statement can be made that the WCAG-conformity increases the usability of a website.}, language = {de} } @techreport{Sivaloganathan, type = {Working Paper}, author = {Sivaloganathan, Janitha}, title = {Die Befristung von Arbeitsverh{\"a}ltnissen in der Rechtsprechung des Bundesarbeitsgerichts}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-15530}, pages = {6}, abstract = {Die Befristung von Arbeitsverh{\"a}ltnissen in der Rechtsprechung des Bundesarbeitsgerichts-Hausarbeit in Grundlagen Recht}, language = {de} } @techreport{Vogt, type = {Working Paper}, author = {Vogt, Thomas}, title = {{\"O}ffentlich-rechtliche Vertr{\"a}ge - Juristische Grundlagen, Sinn, Fallbeispiele}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:1383-opus4-15548}, pages = {6}, abstract = {Der {\"o}ffentlich-rechtliche Vertrag ({\"o}rV) stellt eine Handlungsform des deutschen {\"o}ffentlichen Rechts dar. Es handelt sich um einen Vertrag {\"u}ber einen {\"o}ffentlich-rechtlichen Gegenstand, an dem sich mindestens eine juristische Person des {\"o}ffentlichen Rechts beteiligt. Neben dem Verwaltungsakt stellt er die wichtigste Form des Verwaltungshandelns dar. In diesem Papier werden Grundlagen, Sinn und Anwendung erl{\"a}utert.}, language = {de} }