Lebenswissenschaften und Ethik
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The success of surgical treatment for fractures hinges on various factors, notably accurate surgical indication. The process of developing and certifying a new osteosynthesis device is a lengthy and costly process that requires multiple cycles of review and validation. Current methods, however, often rely on predecessor standards rather than physiological loads in specific anatomical locations. This study aimed to determine actual loads experienced by an osteosynthesis plate, exemplified by a standard locking plate for the femoral shaft, utilizing finite elements analysis (FEA) and to obtain the bending moments for implant development standard tests. A protocol was developed, involving the creation and validation of a fractured femur model fixed with a locking plate, mechanical testing, and FEA. The model’s validation demonstrated exceptional accuracy in predicting deformations, and the FEA revealed peak stresses in the fracture bridging zone. Results of a parametric analysis indicate that larger fracture gaps significantly impact implant mechanical behavior, potentially compromising stability. This study underscores the critical need for realistic physiological conditions in implant evaluations, providing an innovative translational approach to identify internal loads and optimize implant designs. In conclusion, this research contributes to enhancing the understanding of implant performance under physiological conditions, promoting improved designs and evaluations in fracture treatments.
Hintergrund:
In der Physiotherapie existieren zahlreiche Assessments zur Befunderhebung der unteren Extremität bei Kniepatient*innen. Damit können praktizierende Physiotherapeut*innen das Problem der Patient*innen genauer erfassen und dementsprechend die Behandlung aufbauen. Das Ergebnis der Beurteilung einer Patient#ast#in hängt oftmals stark von den Bewertenden ab. Fragestellung: Deshalb überprüft die Studie die Hypothese, ob innerhalb einer Tester*innengruppe mehr gleiche Ausgleichsbewegung bei der Befundung des Sit-to-Stand (STS) anhand von Videomaterial erkannt werden, als es der Standard erwarten würde.
Methode:
In dieser beobachtenden klinischen Querschnittsstudie wurde die Vergleichbarkeit der Befundergebnisse von 4 Therapeut*innen zum abgewandelten STS untersucht. Die zu beurteilenden Proband*innen wurden während der Durchführung des abgewandelten STS standardisiert in der Frontal- und Sagittalebene gefilmt und mittels eines Fragebogens von Berufsanfänger*innen der Physiotherapie beurteilt. Bei dem erstellten Fragebogen handelte es sich um eine systematische Abfrage aller möglichen Bewegungen der großen Gelenke der unteren Extremität mit dichotomen Antwortmöglichkeiten. Eingeschlossen wurden Proband*innen mit oder ohne diagnostizierten Knieproblemen, die älter als 18 Jahre und deutschsprachig sind. Proband*innen mit einschränkenden Nebenerkrankungen wie z.B. neurologische Erkrankungen und Operationen in den letzten 6 Monaten wurden ausgeschlossen. Anschließend wurden die Antworten der Therapeut*innen auf die Übereinstimmung der Ergebnisse überprüft.
Ergebnisse:
Die vollständigen Ergebnisse werden auf dem Poster nachgereicht. Die Interrater-Reliabilität wird mit Hilfe des Fleiss’ Kappa bestimmt. Voraussichtlich werden 25 Proband*innen in die Studie eingeschlossen.
Schlussfolgerung:
Mittels der Ergebnisse soll auf die Interrater-Reliabilität von Bewegungsbefunden des abgewandelten STS bei Kniepatient*innen geschlossen werden
Using markerless motion capture and musculoskeletal models: An evaluation of joint kinematics
(2024)
BACKGROUND: This study presents a comprehensive comparison between a marker-based motion capture system (MMC) and a video-based motion capture system (VMC) in the context of kinematic analysis using musculoskeletal models. OBJECTIVE: Focusing on joint angles, the study aimed to evaluate the accuracy of VMC as a viable alternative for biomechanical research.
METHODS: Eighteen healthy subjects performed isolated movements with 17 joint degrees of freedom, and their kinematic data were collected using both an MMC and a VMC setup. The kinematic data were entered into the AnyBody Modelling System, which enables the calculation of joint angles. The mean absolute error (MAE) was calculated to quantify the deviations between the two systems.
RESULTS: The results showed good agreement between VMC and MMC at several joint angles. In particular, the shoulder, hip and knee joints showed small deviations in kinematics with MAE values of 4.8∘, 6.8∘ and 3.5∘, respectively. However, the study revealed problems in tracking hand and elbow movements, resulting in higher MAE values of 13.7∘ and 27.7∘. Deviations were also higher for head and thoracic movements.
CONCLUSION: Overall, VMC showed promising results for lower body and shoulder kinematics. However, the tracking of the wrist and pelvis still needs to be refined. The research results provide a basis for further investigations that promote the fusion of VMC and musculoskeletal models.
Pelvic floor dysfunction is a common problem in women and has a negative impact ontheir quality of life. The aim of this review was to provide a general overview of the current state oftechnology used to assess pelvic floor functionality. It also provides literature research of the phys-iological and anatomical factors that correlate with pelvic floor health. The systematic review wasconducted according to the PRISMA guidelines. PubMed, ScienceDirect, Cochrane Library andIEEE databases were searched for publications on sensor technology for the assessment of pelvicfloor functionality. Anatomical and physiological parameters were identified through a manualsearch. In the systematic review 115 publications were included. 12 different sensor technologieswere identified. Information on the obtained parameters, sensor position, test activities and subjectcharacteristics were prepared in tabular form from each publication. 16 anatomical and physiologi- cal parameters influencing pelvic floor health were identified in 17 published studies and rankedfor their statistical significance. Taken together, this review could serve as a basis for the develop-ment of novel sensors which could allow for quantifiable prevention and diagnosis, as well as par-ticularized documentation of rehabilitation processes related to pelvic floor dysfunctions.
Pelvic floor dysfunction is a common problem in women and has a negative impact on their quality of life. The aim of this review was to provide a general overview of the current state of technology used to assess pelvic floor functionality. It also provides literature research of the physiological and anatomical factors that correlate with pelvic floor health. This systematic review was conducted according to the PRISMA guidelines. The PubMed, ScienceDirect, Cochrane Library, and IEEE databases were searched for publications on sensor technology for the assessment of pelvic floor functionality. Anatomical and physiological parameters were identified through a manual search. In the systematic review, 114 publications were included. Twelve different sensor technologies were identified. Information on the obtained parameters, sensor position, test activities, and subject characteristics was prepared in tabular form from each publication. A total of 16 anatomical and physiological parameters influencing pelvic floor health were identified in 17 published studies and ranked for their statistical significance. Taken together, this review could serve as a basis for the development of novel sensors which could allow for quantifiable prevention and diagnosis, as well as particularized documentation of rehabilitation processes related to pelvic floor dysfunctions.
Extracorporeal membrane oxygenation (ECMO) was established as a treatment for severe cardiac or respiratory disease. Intra-device clot formation is a common risk. This is based on complex coagulation phenomena which are not yet sufficiently understood. The objective was the development and validation of a methodology to capture the key properties of clots deposed in membrane lungs (MLs), such as clot size, distribution, burden, and composition. One end-oftherapy PLS ML was examined. Clot detection was performed using multidetector computed tomography (MDCT), microcomputed tomography (μCT), and photography of fiber mats (fiber mat imaging, FMI). Histological staining was conducted for von Willebrand factor (vWF), platelets (CD42b, CD62P), fibrin, and nucleated cells (4′, 6-diamidino-2-phenylindole, DAPI). The three imaging
methods showed similar clot distribution inside the ML. Independent of the imaging method, clot loading was detected predominantly in the inlet chamber of the ML. The μCT had the highest accuracy. However, it was more expensive and time consuming than MDCT or FMI. The MDCT detected the clots with low scanning time. Due to its lower resolution, it only showed clotted areas but not
the exact shape of clot structures. FMI represented the simplest variant, requiring little effort and resources. FMI allowed clot localization and calculation of clot volume. Histological evaluation indicated omnipresent immunological deposits throughout the ML. Visually clot-free areas were covered with leukocytes and platelets forming platelet-leukocyte aggregates (PLAs). Cells were embedded in vWF cobwebs, while vWF fibers were negligible. In conclusion, the presented
methodology allowed adequate clot identification and histological classification
of possible thrombosis markers such as PLAs.
Von den modelltheoretischen Grundlagen hin zu konkreten diagnostischen Möglichkeiten, diese komplexe Symptomatik zu erfassen; Zahlreiche Therapieansätze – verständlich, präzise und gezielt in der Praxis anwendbar; Wertvoller Begleiter für Lehrende, Studierende sowie praktisch tätige Therapeutinnen und Therapeuten
Background:
Stroke as a cause of disability in adulthood causes an increasing demand for therapy and care services, including telecare and teletherapy.
Objectives: Aim of the study is to analyse the acceptance of telepresence robotics and digital therapy applications. Methods: Longitudinal study with a before and after survey of patients, relatives and care and therapy staff.
Results: Acceptance of the technology analysed is high in all three groups. Although acceptance among patients declined in parts of the cases in the second survey after having used telerobotics, all in all approval ratings remained high. With regard to patients no significant correlation was found between the general technology acceptance and the acceptance of use of telerobotics.
Conclusion:
Accepted new telecare and teletherapies can be offered with the help of telepresence robotics. This requires knowledge of and experience with the technology.