Lebenswissenschaften und Ethik
Refine
Year of publication
Document Type
- Article (106)
- conference proceeding (article) (86)
- conference talk (37)
- conference proceeding (presentation, abstract) (30)
- Part of a Book (4)
- Doctoral Thesis (3)
- Moving Images (2)
- Other (2)
- conference proceeding (volume) (1)
- Edited collection (1)
Is part of the Bibliography
- no (275)
Keywords
- Biomechanik (13)
- Biomechanics (10)
- Simulation (10)
- Hüftgelenkprothese (9)
- Biomechanische Analyse (7)
- Stent (6)
- Bewegungsapparat (4)
- Finite element analysis (4)
- Spongiosa (4)
- biomechanics (4)
- AnyBody (3)
- Computerunterstütztes Verfahren (3)
- Deformation (3)
- ECMO (3)
- Finite-Elemente-Methode (3)
- Gait analysis (3)
- Inverse dynamics (3)
- Lumbar spine (3)
- Musculoskeletal simulation (3)
- Operationstechnik (3)
- Schultergelenk (3)
- THA (3)
- musculoskeletal simulation (3)
- Adhesives (2)
- Aerosols (2)
- Alter (2)
- Anisotropie (2)
- AnyBody Modeling System (2)
- Ballondilatation (2)
- Belastung (2)
- Biomaterial (2)
- Blood Viscosity (2)
- Breast augmentation (2)
- CFD (2)
- Catheters (2)
- Combined anteversion (2)
- Computertomografie (2)
- Coronary stenting (2)
- Flow visualisation (2)
- Implantation (2)
- Knochen (2)
- Knochenbruch (2)
- Lendenwirbelsäule (2)
- Mechanische Belastung (2)
- Membrane Oxygenator (2)
- Musculoskeletal Modeling (2)
- Nasal airflow (2)
- Numerische Strömungssimulation (2)
- Stiffness (2)
- Stress (2)
- Test (2)
- Tissue Engineering (2)
- Tomographic PIV (2)
- computational fluid dynamics (2)
- stem cells (2)
- total hip replacement (2)
- 3D measurement (1)
- 3D scan (1)
- 3D volumetry (1)
- 3D-Druck (1)
- ANEURYSMS (1)
- ANTERIOR CINGULATE CORTEX (1)
- ANTERIOR CRUCIATE LIGAMENT (1)
- APOPTOSIS (1)
- ARTERIES (1)
- ASCORBIC-ACID (1)
- ASIS (1)
- AUGMENTATION (1)
- Abduction tasks (1)
- Accoucheur (1)
- Acetabulum/physiology (1)
- Adaptive clinical trial (1)
- Aerodynamics (1)
- Aerosole (1)
- Altenpflege (1)
- Aluminum Silicates (1)
- Animals (1)
- Anisotropy (1)
- Antibiotika (1)
- Antioxidant (1)
- Arbeitsbedingungen (1)
- Arbeitshilfe (1)
- Assistenzsystem (1)
- Autologous bone graft (1)
- BIOREACTOR (1)
- BLOOD FLOW (1)
- BLOOD-VESSELS (1)
- BYPASS GRAFTS (1)
- Beckenbruch (1)
- Beckenkammknochen (1)
- Beweglichkeit (1)
- Bewegung (1)
- Bewegungsanalyse (1)
- Bewegungsanalyse <Technik> (1)
- Bildbasierte Verfahren (1)
- Bildgebendes Verfahren (1)
- Bioactivity (1)
- Biological models (1)
- Biologische Modelle (1)
- Biomechanical Phenomena (1)
- Biomechanical investigation (1)
- Blutdruck (1)
- Blutgefäß (1)
- Body Weight (1)
- Bond strength (1)
- Bone harvesting (1)
- Bone imaging (1)
- Bone substitute materials (1)
- Bovine cartilage (1)
- Breast cancer (1)
- Breast implant (1)
- Breathing cycle (1)
- Brusterhaltende Therapie (1)
- Brustkorb (1)
- Brustwirbelsäule (1)
- CANCER (1)
- CELT (1)
- CEUS (1)
- COMPLEX (1)
- CONNECTIVITY (1)
- CONSTRUCTS (1)
- CONTRAST AGENT (1)
- COORDINATE SYSTEM (1)
- COVID-19 (1)
- CULTURES (1)
- Cancellous bone (1)
- Cancer-cells (1)
- Cardiovascular stents (1)
- Cartilage samples (1)
- Catheter (1)
- Ceramics (1)
- Characterisation testing (1)
- Classification (1)
- Coherent motion detection (1)
- Communication engineering education (1)
- Computational Fluid Dynamics Simulation (1)
- Computer-assisted surgery (1)
- Computersimulation (1)
- Computertomographie (1)
- Conventional surgery (1)
- Convolutional neural networks (1)
- Coronary (1)
- Coronary artery (1)
- Corrosion rate (1)
- Corrosion test (1)
- Covid-19 (1)
- Crimping (1)
- Cup medialisation (1)
- DEFICIENCY (1)
- Damage (1)
- Damage mechanism (1)
- Deep Learning (1)
- Deep learning fluid mechanics (1)
- Deformation behaviour (1)
- Dental Materials (1)
- Dental alloys (1)
- Dental membrane (1)
- Dentin (1)
- Depression (1)
- Deutschland (1)
- Distraktion (1)
- Dragonfly (1)
- Dragonfly wing (1)
- Dreidimensionale Bildverarbeitung (1)
- EARLY OSTEOARTHRITIS (1)
- ECMO SYSTEMS (1)
- EMG (1)
- Early recovery (1)
- Einflussgröße (1)
- Elasticity (1)
- Electromyography (1)
- Elektromyographie (1)
- Elite athletes (1)
- Ellenbogenstabilität (1)
- Empfindlichkeit (1)
- Endotracheal Intubation (1)
- Endotracheal Tube (1)
- Equipment Failure Analysis/statistics & numerical data (1)
- Ergonomics (1)
- Ermüdung (1)
- Ermüdungsbruch (1)
- Euler-Bernoulli-Beam-Theory (1)
- Ex vivo porcine stent model (1)
- Extracorporeal Membrane Oxygenation/instrumentation (1)
- FEA (1)
- FORCE (1)
- FRONTAL-CORTEX (1)
- Fat graft (1)
- Fatigue (1)
- Fatigue fracture (1)
- Feedback (1)
- Femur first (1)
- Finite element (1)
- Finite element analysis (FEA) (1)
- Flow (1)
- Fluid Mechanics (1)
- Football (1)
- Functional MRI (1)
- Funktionelle Anatomie (1)
- GAIT (1)
- GULO (1)
- Gait (1)
- Ganganalyse (1)
- Gefäßverletzung (1)
- Gehen (1)
- Geometrical imperfections (1)
- Geometrie (1)
- Germany (1)
- Glenohumeral joint reaction force (1)
- Glenohumeral stability (1)
- Gliding Flight (1)
- Ground Reaction Force Prediction (1)
- HYDROGELS (1)
- Haltungsfehler (1)
- Haut (1)
- Head trauma (1)
- Heat treatment (1)
- Hemodynamics (1)
- Hip Prosthesis (1)
- Hochschulschrift (1)
- Humans (1)
- Hyaluronsäure (1)
- Hämodynamik (1)
- Hüftgelenk (1)
- Hüftgelenkpfanne (1)
- IMMEDIATE BREAST RECONSTRUCTION (1)
- IMU (1)
- IN-VITRO (1)
- INFLAMMATION (1)
- INJURY (1)
- INSTABILITY (1)
- Iliac crest (1)
- Indentation test (1)
- Indian ink (1)
- Inertial Measurement Units (1)
- Injury score (1)
- Internal fixator (1)
- Ion release (1)
- Joint Reaction Forces (1)
- Kardiovaskuläres System (1)
- Kennzeichnung (1)
- Kicks (1)
- Kniegelenk (1)
- Kniegelenkband (1)
- Knochenbildung (1)
- Knochenentnahme (1)
- Knochenersatz (1)
- Knorpel (1)
- Knowledge engineering (1)
- Kontaktkraft (1)
- Kopfverletzung (1)
- Koronare Herzkrankheit (1)
- Koronarendoprothese (1)
- Körper (1)
- Körperliche Belastung (1)
- Künstliche Intelligenz (1)
- Laser powder bed fusion (L-PBF) (1)
- Lasers (1)
- Lastverteilung <Statik> (1)
- Le Fort III (1)
- Leg length (1)
- Leistungssportler (1)
- Leitfähgkeit (1)
- Lendenwirbelsäulenkrankheit (1)
- Ligament stiffness (1)
- Linear Models (1)
- Lipofilling (1)
- MAMMAPLASTY (1)
- MDCT (1)
- MECHANICAL PROPERTIES (1)
- MECHANICAL-PROPERTIES (1)
- MEDICINAL PLANTS (1)
- MITOCHONDRIAL DYSFUNCTION (1)
- MOTION (1)
- MRI (1)
- MULTIDETECTOR COMPUTED-TOMOGRAPHY (1)
- Magnesium (1)
- Mammoplastik (1)
- Material properties (1)
- Measurement and testing (1)
- Mechanical Phenomena (1)
- Mechanical behaviour (1)
- Mechanical properties (1)
- Medizintechnik (1)
- Mehrkörpersimulation (1)
- Membrane/classification/standards/statistics & numerical data (1)
- Meniskusschaden (1)
- Mensch (1)
- Mesenchymzelle (1)
- Method labeling (1)
- Micro-structure (1)
- Minimal-invasive Chirurgie (1)
- Modell (1)
- Motion Capture (1)
- Motion Capturing (1)
- Motion capture (1)
- Movement (1)
- Multibody Simulation (1)
- Multiphase blood flow (1)
- Multiresistant (1)
- Mund-Kiefer-Gesichts-Chirurgie (1)
- Muscle (1)
- Muscle influence (1)
- Muscle model (1)
- Muscle trajectory (1)
- Muscle weakness (1)
- Muscles (1)
- Muscoloskeletal model (1)
- Musculoskeletal Simulation (1)
- Musculoskeletal analysis (1)
- Musculoskeletal model (1)
- Musculoskeletal modelling (1)
- Musculoskeletal system (1)
- Muskelkraft (1)
- Muskuloskelettale Simulation (1)
- Nabelvene (1)
- Nachweis (1)
- Nanoparticles (1)
- Non-Newtonian multiphase flow (1)
- Numerische Methode (1)
- OSTEOARTHRITIS (1)
- OUTCOMES (1)
- OXIDATIVE STRESS (1)
- OXYGENATION (1)
- Offset (1)
- Orthopädische Chirurgie (1)
- Osteoconductive (1)
- Osteomyelitis (1)
- Osteosynthese (1)
- Osteotomie (1)
- Outcome (1)
- PCR (1)
- PHOSPHATIDYLCHOLINE (1)
- PLATELET ACTIVATION (1)
- PLATELET-RICH PLASMA (1)
- POLYPHENOLS (1)
- PREDICTOR (1)
- Pandemie (1)
- Parameter study (1)
- Particle Image Velocimetry (1)
- Pelvic ring fracture (1)
- Pelvis (1)
- Perceptual learning (1)
- Percutaneous coronary intervention (1)
- Physiological Breathing (1)
- Polymer (1)
- Polymerase-Kettenreaktion (1)
- Polymers (1)
- Powders (1)
- Precious alloys (1)
- Primary Health Care/statistics & numerical data (1)
- Prognose (1)
- Prosthesis Design (1)
- Prüfung (1)
- Pulleys (1)
- QUANTIFICATION (1)
- RADIATION-THERAPY (1)
- RECIPIENT-SITE (1)
- RTMS (1)
- Radiotherapy (1)
- Randomized (1)
- Rapamycin (1)
- Rapid prototyping (1)
- Reconstruction (1)
- Resilience, psychological (1)
- Resilienz, psychologische (1)
- Resistance to corrosion (1)
- Respiratory Distress Syndrome/therapy (1)
- Restenosis (1)
- Retrospective Studies (1)
- Rind (1)
- Robot sensing systems (1)
- Robotik (1)
- Rotator cuff tears (1)
- Rotatorenmanschettenriss (1)
- SARS-CoV-2 (1)
- SHAPE (1)
- STIFFNESS (1)
- STIMULATION (1)
- Sagittal balance (1)
- Schulkind (1)
- Schädel-Hirn-Trauma (1)
- Second-harmonic generation imaging (1)
- Severity of Illness Index (1)
- Shear Raed Induced Coagulation (1)
- Shear Rate Induced Coagulation (1)
- Shoulder joint (1)
- Shoulder joint complex (1)
- Signals (1)
- Silent Breathing (1)
- Softening (1)
- Specimen preparation and treatment (1)
- Speedcourt (1)
- Spinal fusion (1)
- Spine biomechanics (1)
- Stabilität (1)
- Steifigkeit (1)
- Stent design (1)
- Stent implantation (1)
- Stent screening (1)
- Stent-artery interaction (1)
- Stents (1)
- Stress, Mechanical (1)
- Surface Properties (1)
- Surface treatments (1)
- Surgical smoke (1)
- T-peel configuration (1)
- THR (1)
- THROMBOSIS (1)
- THROMBOTIC DEPOSITS (1)
- TMS (1)
- Task analysis (1)
- Testing biomaterials (1)
- Thoracolumbar spine (1)
- Time factors (1)
- Tinte (1)
- Topographic shift (1)
- Torus (1)
- Total hip athroplasty (1)
- Tracheotomies (1)
- Transfer functions (1)
- Turbulent Kinetic Energy (1)
- Valves (1)
- Vascular injury (1)
- Vergleichende Anatomie (1)
- Verletzung (1)
- Vertebra (1)
- Violinspiel (1)
- Viscoelasticity (1)
- Webcast (1)
- Werkstoff (1)
- Wirbelsäule (1)
- Wirbelsäulenversteifung (1)
- Wrapping (1)
- aerodynamics (1)
- anchorage (1)
- anti-Inflammatory agent (1)
- attention (1)
- biomaterial (1)
- biomechanical implant test (1)
- blood (1)
- bone biomechanics (1)
- brain mapping (1)
- cancer (1)
- cell- free DNA (1)
- cell-enriched lipotransfer (1)
- chemical synthesis (1)
- children (1)
- chondrocytes (1)
- coagulation (1)
- collagen (1)
- combined anteversion (1)
- component position (1)
- computer-assisted orthopaedic surgery (1)
- cortical plasticity (1)
- critical hip joint loading (1)
- crosstalk (1)
- cup loading (1)
- data-driven analysis (1)
- design (1)
- distraction (1)
- drug-eluting stent (1)
- dynamic multiplanar loading (1)
- elbow stability (1)
- electromyography (1)
- embodiment (1)
- emotion (1)
- enhanced resorption (1)
- esb (1)
- extracellular matrix (1)
- fMRI BOLD (1)
- fat grafting (1)
- femoral fracture (1)
- femoral offset (1)
- finite elements analysis (1)
- flexibility ellipsis (1)
- force angles (1)
- force pathways (1)
- form-finding (1)
- functional outcome (1)
- functionality (1)
- gait analysis (1)
- gargle (1)
- gliding flight (1)
- happiness (1)
- high-impact exercisess (1)
- hip contact force (1)
- hip fractureg (1)
- histological evaluation (1)
- human articular cartilage (1)
- human umbilical vein (1)
- humeroradial stability (1)
- hydrogels (1)
- immune system (1)
- implant migration (1)
- inertial measurement units (1)
- infiltration (1)
- inflammation (1)
- influence parameters (1)
- insect flight (1)
- kinematics (1)
- language assessment (1)
- ligaments (1)
- lipoaspirate (1)
- lipograft (1)
- liposomal packing (1)
- lower back load (1)
- lumbar geometry (1)
- lumbar spine (1)
- macular degeneration (1)
- mechanical compliance (1)
- membrane lung (1)
- meniscus (1)
- multifidus (1)
- muscle activity (1)
- muscle injury (1)
- muscle recruitment (1)
- musculoskeletal disease (1)
- musculoskeletal modeling (1)
- musculoskeletal system (1)
- neutrophil extracellular traps (1)
- optical motion capture (1)
- osteoarthritis (1)
- osteoporosis (1)
- pandemic (1)
- patient specific loading (1)
- pelvic floor (1)
- pelvic tilt (1)
- perceptual learning (1)
- pharmacology (1)
- pooling (1)
- proteolysis (1)
- radial head arthroplasty (1)
- radial head prostheses (1)
- range of motion (1)
- rapamycin (1)
- resting-state fMRI (1)
- rheological model (1)
- rim loading (1)
- sadness (1)
- scaffolds (1)
- schools (1)
- sensitivity study (1)
- sensors (1)
- shear induced clotting (1)
- shoulder elevation (1)
- shoulder joint force (1)
- simplified loading model (1)
- sirolimus (1)
- small calibre graft (1)
- sonography (1)
- stent platform (1)
- subject-specific musculoskeletal modeling (1)
- subluxation (1)
- surface electromyography (1)
- surgery (1)
- tannic acid (1)
- task-based fMRI (1)
- tensegrity joint (1)
- therapeutic use (1)
- three-dimensional computed tomography analysis (1)
- tissue engineering (1)
- tissue regeneration (1)
- total hip anthroplasty (1)
- total hip arthroplasty (1)
- toxicity (1)
- tracheobronchial mucus (1)
- vWF (1)
- validation (1)
- vascular tissue engineering (1)
- vector (1)
- violin (1)
- viscoelasticity (1)
- visual cortex (1)
- vitamin C (1)
- von Willebrand factor (1)
- wearable motion-tracking sensors (1)
- white adipose tissue (1)
- zwitterionic monomers (1)
- µCT (1)
Institute
- Fakultät Maschinenbau (275) (remove)
Begutachtungsstatus
- peer-reviewed (98)
- begutachtet (10)
Fragestellung
Es soll in dieser Computersimulationsstudie untersucht werden, wie der Osteosyntheseverbund Platte mit Schrauben im Verbund mit einer im mittleren Drittel gebrochenen Clavicula durch das Bewegungsausmaß
in vivo belastet ist. Was sind die grundlegenden Kräfte die auf Clavicula und Implantat wirken und welchen Einfl uss hat die Bruchform.
Methodik
Die Muskel- und Gelenkkräfte sowie die Belastung des Implantatverbundes wurden mit einer muskuloskelletalen
Simulationssoftware (AnyBody Technology, V.4) berechnet. Hierfür wurden mit einem komplexen Model des menschlichen Körpers folgende Bewegungen analysiert: eine Flexion von 160° und Abduktion 160° mit
einem Gewicht von 2 kg in der Hand. Aus CT-Patientendaten wurden zwei dreidimensionale Modelle des Clavicula-Implantat Verbundes gebildet, die sich in der Frakturform unterscheiden (Querfraktur und vertikale
Fraktur). In beiden Modellen wurde eine Claviculaosteosynthese in superiorer Position mit einer 6 Loch LCP mit 2 Schrauben pro Hauptfragment verwendet. Die Materialeigenschaften wurden aus der Dichte des Materials sowie aus Literaturdaten verwendet. Die Muskel- und Gelenkkräfte aus der muskuloskelletalen Berechnung wurden auf das Finite Elemente Modell übertragen und die Spannungen und Dehnungen des Implantat-Knochenverbundes
wurden berechnet.
Ergebnisse
Es zeigte sich, dass die simulierte in vivo Belastung stark abhängig vom Flexionswinkel ist. Das Implantat ist in der superioren Lage auf Biegung belastet, welche maximale Werte im Überschulterniveau erreicht. Die Bruchform mit anatomischer Reposition und Kontakt der Hauptfragmente zueinander führt zu einer deutlichen Entlastung des Osteosyntheseverbundes im Vergleich zu einer Bruchform mit vertikaler Fraktur.
Schlussfolgerung
Aus den Analysen ist eine Positionierung der Plattenosteosynthese für die im mittleren Drittel frakturierte Clavicula in anterior-superiorer Lage wünschenswert. Die anatomische Reposition entlastet den Osteosyntheseverbund und sollte möglichst erreicht werden. Die Nachbehandlung sollte ein Bewegungsausmaß für den Arm für 4 Wochen für einfache Bruchformen auf 70° Flexion und Abduktion limitieren und für komplexe Bruchformen diese Limitierung ausgedehnt werden.