TY - JOUR A1 - Currle, Edda A1 - Haug, Sonja A1 - Weber, Karsten T1 - Akzeptanz des Einsatzes von Künstlicher Intelligenz im Anamneseprozess: Ergebnisse einer Bevölkerungsbefragung in Deutschland JF - Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen N2 - Hintergrund und Zielsetzung Zunehmend werden digitale Anamneseverfahren, wie z. B. Chatbots, entwickelt und evaluiert, sind jedoch in Arztpraxen in Deutschland noch nicht flächendeckend implementiert. Ziel dieser Arbeit ist die Erhebung der Akzeptanz der Bevölkerung in Deutschland gegenüber KI-gestützten Verfahren im Anamneseprozess, durch die es möglich wird, Rückschlüsse auf die Nutzung der Verfahren und ihre Eignung als Bestandteil von Digitalisierungsstrategien der Praxen zu ziehen. Methode Die Studie basiert auf einer Onlinebefragung der Bevölkerung in Deutschland (Feldphase 18.-24.11.2024, n = 1.000). Zurückgehend auf die „Unified Theory of Acceptance and Use of Technology“ (UTAUT) wurden drei zentrale Hypothesen zur Nutzung von Künstlicher Intelligenz (KI) im Anamneseprozess aufgestellt und mit linearen Regressionsmodellen getestet. Ergebnisse Die Akzeptanz für die Nutzung von KI-gestützten Systemen fällt in beiden untersuchten Szenarien, der Nutzung eines Chatbots zu Hause und der Nutzung eines Chatbots in einer Arztpraxis, hoch aus. Dabei bestätigen sich die erwarteten Zusammenhänge von Leistungserwartung, Aufwandserwartung und erwartetem Sozialem Einfluss mit der Verhaltensabsicht, einen Chatbot in der Arztpraxis oder vor dem Besuch einer Arztpraxis zu nutzen. Die Einflüsse von Alter, Geschlecht oder Erfahrung mit der Technologie zeigen jedoch nicht die vermuteten Zusammenhänge. Diskussion und Schlussfolgerung Die Praktikabilität ist von entscheidender Bedeutung für eine positive Einstellung gegenüber der Nutzung. Dabei zeigt sich kein Unterschied zwischen den Geschlechtern. Bei der Implementierung von Chatbots im Anamneseprozess sollten die Aspekte Praktikabilität, Datenschutz und Datensicherheit eine wesentliche Rolle spielen. Angesichts der Tatsache, dass ein großer Teil der älteren Bevölkerung in Deutschland nach wie vor über begrenzte Erfahrung mit digitalen Technologien verfügt, ist Gebrauchstauglichkeit für diese Bevölkerungsgruppe sowie für Menschen mit Beeinträchtigungen von hoher Relevanz. N2 - Background and objectives Digital tools for medical history-taking, such as chatbots, are increasingly being developed and evaluated but have not yet been implemented across the board in medical practices in Germany. The aim of this study was to survey the acceptance of AI-supported tools for medical history-taking among the German population, thereby allowing conclusions to be drawn about the use of these tools and their suitability as part of digitalization strategies in medical practices. Method The study is based on an online survey among the German population (fieldwork November 18 to 24, 2024, n = 1,000). Based on the ‘Unified Theory of Acceptance and Use of Technology’ (UTAUT), three central hypotheses on the use of artificial intelligence (AI) in the medical history-taking process were generated and tested using linear regression models. Results In the two scenarios examined — patients using a chatbot at home and at the doctor’s office — there was a high level of acceptance for the use of AI-supported systems. The expected relationships between Performance Expectancy, Effort Expectancy and expected Social Influence with the behavioral intention to use a chatbot either in the doctor’s office or before visiting the doctor’s office have been confirmed. However, influential factors such as age, gender, or experience with technology do not show the expected correlations. Discussion and conclusion Practicability is crucial for a favorable attitude towards AI applications. There were no apparent gender differences. When implementing chatbots in the medical history-taking process, the aspects of practicability, data protection, and data security should play a key role. Given that a large number of the elderly in Germany still have limited experience with digital technologies, usability is highly relevant for both this population group and for people with disabilities. T2 - Acceptance of artificial intelligence tools for medical history-taking: Findings of a population survey in Germany KW - Künstliche Intelligenz KW - Anamnese KW - Technologieakzeptanz KW - UTAUT KW - Bevölkerungsumfrage Y1 - 2025 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-86715 N1 - Corresponding author der OTH Regensburg: Edda Currle VL - 198-199 SP - 9 EP - 17 PB - Elsevier ER - TY - JOUR A1 - Weiherer, Maximilian A1 - Eigenberger, Andreas A1 - Egger, Bernhard A1 - Brébant, Vanessa A1 - Prantl, Lukas A1 - Palm, Christoph T1 - Learning the shape of female breasts: an open-access 3D statistical shape model of the female breast built from 110 breast scans JF - The Visual Computer N2 - We present the Regensburg Breast Shape Model (RBSM)—a 3D statistical shape model of the female breast built from 110 breast scans acquired in a standing position, and the first publicly available. Together with the model, a fully automated, pairwise surface registration pipeline used to establish dense correspondence among 3D breast scans is introduced. Our method is computationally efficient and requires only four landmarks to guide the registration process. A major challenge when modeling female breasts from surface-only 3D breast scans is the non-separability of breast and thorax. In order to weaken the strong coupling between breast and surrounding areas, we propose to minimize the variance outside the breast region as much as possible. To achieve this goal, a novel concept called breast probability masks (BPMs) is introduced. A BPM assigns probabilities to each point of a 3D breast scan, telling how likely it is that a particular point belongs to the breast area. During registration, we use BPMs to align the template to the target as accurately as possible inside the breast region and only roughly outside. This simple yet effective strategy significantly reduces the unwanted variance outside the breast region, leading to better statistical shape models in which breast shapes are quite well decoupled from the thorax. The RBSM is thus able to produce a variety of different breast shapes as independently as possible from the shape of the thorax. Our systematic experimental evaluation reveals a generalization ability of 0.17 mm and a specificity of 2.8 mm. To underline the expressiveness of the proposed model, we finally demonstrate in two showcase applications how the RBSM can be used for surgical outcome simulation and the prediction of a missing breast from the remaining one. Our model is available at https://www.rbsm.re-mic.de/. KW - Statistical shape model KW - Non-rigid surface registration KW - Breast imaging KW - Surgical outcome simulation KW - Breast reconstruction surgery Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-30506 N1 - Corresponding author: Christoph Palm N1 - Zugehörige arXiv-Publikation: https://opus4.kobv.de/opus4-oth-regensburg/frontdoor/index/index/docId/2023 VL - 39 IS - 4 SP - 1597 EP - 1616 PB - Springer Nature ER - TY - JOUR A1 - Brébant, Vanessa A1 - Weiherer, Maximilian A1 - Noisser, Vivien A1 - Seitz, Stephan A1 - Prantl, Lukas A1 - Eigenberger, Andreas T1 - Implants Versus Lipograft: Analysis of Long-Term Results Following Congenital Breast Asymmetry Correction JF - Aesthetic Plastic Surgery N2 - Aims Congenital breast asymmetry represents a particular challenge to the classic techniques of plastic surgery given the young age of patients at presentation. This study reviews and compares the long-term results of traditional breast augmentation using silicone implants and the more innovative technique of lipografting. Methods To achieve this, we not only captured subjective parameters such as satisfaction with outcome and symmetry, but also objective parameters including breast vol-ume and anthropometric measurements. The objective examination was performed manually and by using the Vectra H2 photogrammetry scanning system. Results Differences between patients undergoing either implant augmentation or lipograft were revealed not to be significant with respect to patient satisfaction with surgical outcome (p= 0.55) and symmetry (p= 0.69). Furthermore, a breast symmetry of 93 % was reported in both groups. Likewise, no statistically significant volume difference between the left and right breasts was observed in both groups (p\0.41). However, lipograft patients needed on average 2.9 procedures to achieve the desired result, compared with 1.3 for implant augmentation. In contrast, patients treated with implant augmentation may require anumber of implant changes during their lifetime. Conclusion Both methods may be considered for patients presenting with congenital breast asymmetry. KW - Congenital Breast Asymmetry KW - 3D volumetry KW - Autologous fat injections KW - Three-dimensional imaging KW - Lipograft Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-32404 N1 - Corresponding author der OTH Regensburg: Vanessa Brébant VL - 46 SP - 2228 EP - 2236 PB - Springer Nature ER - TY - JOUR A1 - Maier, Johannes A1 - Weiherer, Maximilian A1 - Huber, Michaela A1 - Palm, Christoph T1 - Imitating human soft tissue on basis of a dual-material 3D print using a support-filled metamaterial to provide bimanual haptic for a hand surgery training system JF - Quantitative Imaging in Medicine and Surgery N2 - Background: Currently, it is common practice to use three-dimensional (3D) printers not only for rapid prototyping in the industry, but also in the medical area to create medical applications for training inexperienced surgeons. In a clinical training simulator for minimally invasive bone drilling to fix hand fractures with Kirschner-wires (K-wires), a 3D-printed hand phantom must not only be geometrically but also haptically correct. Due to a limited view during an operation, surgeons need to perfectly localize underlying risk structures only by feeling of specific bony protrusions of the human hand. Methods: The goal of this experiment is to imitate human soft tissue with its haptic and elasticity for a realistic hand phantom fabrication, using only a dual-material 3D printer and support-material-filled metamaterial between skin and bone. We present our workflow to generate lattice structures between hard bone and soft skin with iterative cube edge (CE) or cube face (CF) unit cells. Cuboid and finger shaped sample prints with and without inner hard bone in different lattice thickness are constructed and 3D printed. Results: The most elastic available rubber-like material is too firm to imitate soft tissue. By reducing the amount of rubber in the inner volume through support material (SUP), objects become significantly softer. Without metamaterial, after disintegration, the SUP can be shifted through the volume and thus the body loses its original shape. Although the CE design increases the elasticity, it cannot restore the fabric form. In contrast to CE, the CF design increases not only the elasticity but also guarantees a local limitation of the SUP. Therefore, the body retains its shape and internal bones remain in its intended place. Various unit cell sizes, lattice thickening and skin thickness regulate the rubber material and SUP ratio. Test prints with higher SUP and lower rubber material percentage appear softer and vice versa. This was confirmed by an expert surgeon evaluation. Subjects adjudged pure rubber-like material as too firm and samples only filled with SUP or lattice structure in CE design as not suitable for imitating tissue. 3D-printed finger samples in CF design were rated as realistic compared to the haptic of human tissue with a good palpable bone structure. Conclusions: We developed a new dual-material 3D print technique to imitate soft tissue of the human hand with its haptic properties. Blowy SUP is trapped within a lattice structure to soften rubber-like 3D print material, which makes it possible to reproduce a realistic replica of human hand soft tissue. KW - Dual-material 3D printing KW - Hand surgery training KW - Metamaterial KW - Support material KW - Tissue-imitating hand phantom KW - Handchirurgie KW - 3D-Druck KW - Biomaterial KW - Lernprogramm Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-979 N1 - Corresponding author: Christoph Palm VL - 9 IS - 1 SP - 30 EP - 42 PB - AME Publishing Company ER - TY - JOUR A1 - Maier, Johannes A1 - Weiherer, Maximilian A1 - Huber, Michaela A1 - Palm, Christoph T1 - Optically tracked and 3D printed haptic phantom hand for surgical training system JF - Quantitative Imaging in Medicine and Surgery N2 - Background: For surgical fixation of bone fractures of the human hand, so-called Kirschner-wires (K-wires) are drilled through bone fragments. Due to the minimally invasive drilling procedures without a view of risk structures like vessels and nerves, a thorough training of young surgeons is necessary. For the development of a virtual reality (VR) based training system, a three-dimensional (3D) printed phantom hand is required. To ensure an intuitive operation, this phantom hand has to be realistic in both, its position relative to the driller as well as in its haptic features. The softest 3D printing material available on the market, however, is too hard to imitate human soft tissue. Therefore, a support-material (SUP) filled metamaterial is used to soften the raw material. Realistic haptic features are important to palpate protrusions of the bone to determine the drilling starting point and angle. An optical real-time tracking is used to transfer position and rotation to the training system. Methods: A metamaterial already developed in previous work is further improved by use of a new unit cell. Thus, the amount of SUP within the volume can be increased and the tissue is softened further. In addition, the human anatomy is transferred to the entire hand model. A subcutaneous fat layer and penetration of air through pores into the volume simulate shiftability of skin layers. For optical tracking, a rotationally symmetrical marker attached to the phantom hand with corresponding reference marker is developed. In order to ensure trouble-free position transmission, various types of marker point applications are tested. Results: Several cuboid and forearm sample prints lead to a final 30 centimeter long hand model. The whole haptic phantom could be printed faultless within about 17 hours. The metamaterial consisting of the new unit cell results in an increased SUP share of 4.32%. Validated by an expert surgeon study, this allows in combination with a displacement of the uppermost skin layer a good palpability of the bones. Tracking of the hand marker in dodecahedron design works trouble-free in conjunction with a reference marker attached to the worktop of the training system. Conclusions: In this work, an optically tracked and haptically correct phantom hand was developed using dual-material 3D printing, which can be easily integrated into a surgical training system. KW - Handchirurgie KW - 3D-Druck KW - Lernprogramm KW - Zielverfolgung KW - HaptiVisT KW - Dual-material 3D printing KW - hand surgery training KW - metamaterial KW - tissue imitating phantom hand Y1 - 2020 U6 - https://doi.org/10.21037/qims.2019.12.03 N1 - Corresponding author: Christoph Palm VL - 10 IS - 02 SP - 340 EP - 455 PB - AME Publishing Company CY - Hong Kong, China ER - TY - JOUR A1 - Ebigbo, Alanna A1 - Mendel, Robert A1 - Probst, Andreas A1 - Manzeneder, Johannes A1 - Souza Jr., Luis Antonio de A1 - Papa, João Paulo A1 - Palm, Christoph A1 - Messmann, Helmut T1 - Computer-aided diagnosis using deep learning in the evaluation of early oesophageal adenocarcinoma JF - GuT N2 - Computer-aided diagnosis using deep learning (CAD-DL) may be an instrument to improve endoscopic assessment of Barrett’s oesophagus (BE) and early oesophageal adenocarcinoma (EAC). Based on still images from two databases, the diagnosis of EAC by CAD-DL reached sensitivities/specificities of 97%/88% (Augsburg data) and 92%/100% (Medical Image Computing and Computer-Assisted Intervention [MICCAI] data) for white light (WL) images and 94%/80% for narrow band images (NBI) (Augsburg data), respectively. Tumour margins delineated by experts into images were detected satisfactorily with a Dice coefficient (D) of 0.72. This could be a first step towards CAD-DL for BE assessment. If developed further, it could become a useful adjunctive tool for patient management. KW - Speiseröhrenkrebs KW - Diagnose KW - Computerunterstütztes Verfahren KW - Maschinelles Lernen Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-68 N1 - Corresponding authors: Alanna Ebigbo and Christoph Palm VL - 68 IS - 7 SP - 1143 EP - 1145 PB - British Society of Gastroenterology ER - TY - JOUR A1 - Safi, Hila A1 - Bandic, Medina A1 - Niedermeier, Christoph A1 - Almudever, Carmen G. A1 - Feld, Sebastian A1 - Mauerer, Wolfgang T1 - Stacking the odds: full-stack quantum system design space exploration JF - EPJ Quantum Technology N2 - Design space exploration (DSE) plays an important role in optimising quantum circuit execution by systematically evaluating different configurations of compilation strategies and hardware settings. In this paper, we conduct a comprehensive investigation into the impact of various layout methods, qubit routing techniques, and optimisation levels, as well as device-specific properties such as different variants and strengths of noise and imperfections, the topological structure of qubits, connectivity densities, and back-end sizes. By spanning through these dimensions, we aim to understand the interplay between compilation choices and hardware characteristics. A key question driving our exploration is whether the optimal selection of device parameters, mapping techniques, comprising of initial layout strategies and routing heuristics can mitigate device induced errors beyond standard error mitigation approaches. Our results show that carefully selecting software strategies (e.g., mapping and routing algorithms) and tailoring hardware characteristics (such as minimising noise and leveraging topology and connectivity density) significantly improve the fidelity of circuit execution outcomes, and thus the expected correctness or success probability of the computational result. We provide estimates based on key metrics such as circuit depth, gate count and expected fidelity. Our results highlight the importance of hardware–software co-design, particularly as quantum systems scale to larger dimensions, and along the way towards fully error corrected quantum systems: Our study is based on computationally noisy simulations, but considers various implementations of quantum error correction (QEC) using the same approach as for other algorithms. The observed sensitivity of circuit fidelity to noise and connectivity suggests that co-design principles will be equally critical when integrating QEC in future systems. Our exploration provides practical guidelines for co-optimising physical mapping, qubit routing, and hardware configurations in realistic quantum computing scenarios. Y1 - 2025 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-85157 N1 - Corresponding author der OTH Regensburg: Hila Safi VL - 12 PB - Springer CY - Heidelberg ER - TY - CHAP A1 - Graf, Julian A1 - Hachani, Murad A1 - Fischer, Sebastian A1 - Hackenberg, Rudolf T1 - A heuristic packet processing model for improved encrypted network analysis T2 - CSCS '25: Proceedings of the 2nd Cyber Security in CarS Workshop N2 - Modern networked systems, such as those in the automotive sector, face increasing complexity and growing attack surfaces due to the rise of interconnected and data-driven technologies. Detecting malicious behavior in these environments requires efficient and scalable methods that can operate reliably despite limited resources and high communication volumes. This paper proposes a heuristic packet processing model designed to support intrusion detection based on structural and temporal characteristics of encrypted network traffic. The model follows a modular architecture consisting of four key phases: recording, sorting, prioritizing, and analyzing. At the core of the approach is the Polymetric Queueing Topology Space, a feature space that combines statistical and time series attributes derived from model structure and flow data. These features serve as input for machine learning models, which can effectively distinguish between benign and intrusion traffic patterns without relying on packet data beyond the transport layer. The approach was evaluated using the publicly available ToN_IoT dataset and demonstrated that reliable classification is achievable using a subset of the developed feature space that contains model-derived traffic features. We used Random Forest for supervised binary and multi-class classification achieving high accuracy scores of 99% for binary and 98% for multi-class classification. Additionally, for unsupervised anomaly detection, we created an Isolation Forest model accomplishing F1-scores of 0.92 for the benign and 0.96 for intrusion class. The architecture is designed to enable dynamic traffic prioritization and to offer a flexible foundation that can observe diverse network domains while maintaining efficient performance under constrained computational conditions. Y1 - 2025 U6 - https://doi.org/10.1145/3736130.3764510 PB - ACM CY - New York, USA ER - TY - JOUR A1 - Heberl, Michael A1 - Hofrichter, Andreas A1 - Rank, Daniel A1 - Bauer, Franz A1 - Sterner, Michael T1 - Influence of plant dimensioning and location on the ecology of PEM electrolysis JF - International Journal of Hydrogen Energy N2 - PV and wind systems with PEM electrolysis offer great potential for producing hydrogen with low emissions. Our research has identified the ecologically optimal size of PEM in relation to fixed PV/wind capacities. We calculate efficiencies and production volumes for PEM with 240 capacity and site variations. We analyse the global warming potential of all systems and draw conclusions about the optimal system design. The lowest GWP is achieved at the site with the highest full load hours with 1.32 kg CO2-eq/kg H2 (Wind, 28 MW electrolysis) and 4.24 kg CO2-eq/kg H2 (PV, 23 MW electrolysis). We have identified a clear trend: increasing PV/wind full load hours leads to higher ideal PEM capacities. However, there is a significant discrepancy between the ideal economic and ecological capacity. Furthermore, higher electrolysis capacities can achieve lower emissions as they increasingly operate at a more efficient partial load. KW - Electrolysis KW - Life cycle analysis KW - Global warming potential KW - Plant design KW - Renewable energy Y1 - 2025 U6 - https://doi.org/10.1016/j.ijhydene.2025.151039 SN - 0360-3199 VL - 167 PB - Elsevier ER - TY - CHAP A1 - Stocker, Philipp A1 - Lehrer, Tobias A1 - Duddeck, Fabian A1 - Wagner, Marcus T1 - Face-wise prediction of sheet-metal drawability using graph neural networks T2 - Journal of Physics: Conference Series N2 - The early design phase of deep-drawn structural components involves time-consuming iterative development. Traditional drawability assessments rely on finite element simulations, which are computationally expensive and slow the design process. Alternative machine learning (ML) approaches show promise in accelerating this process but face challenges with existing methods. Existing low-dimensional ML models only provide global predictions without identifying specific geometric regions prone to failure. High-dimensional models provide local predictions but require significant amounts of training data. We propose a data-driven approach leveraging graph neural networks (GNNs) for face-wise drawability prediction of sheet metal components in their computer-aided design (CAD) representation. Our method aims to bridge the gap between the computational efficiency of ML and the spatial resolution of simulation by providing face-wise insight into potential failure regions. This study utilises a dataset of parametric U-channel geometries with variability in both geometry and topology. Ground-truth labels are generated using inverse analysis simulations. Geometric entities are represented through the use of UV parameterisations, whereby 3D surfaces are mapped into 2D space to facilitate geometric encoding. Concurrently, the topological relationships are captured using a face adjacency graph. To address data scarcity, we evaluate how different amounts of training data affect model performance and perform ablation studies to analyse the impact of different CAD representation features. Our results show that the proposed approach achieves high accuracy even with limited training data. In addition, the ablation studies provide insights into the most critical CAD features, guiding future research. These results highlight the potential of our GNN to predict face-wise drawability in the early design phase. Y1 - 2025 U6 - https://doi.org/10.1088/1742-6596/3104/1/012053 SN - 1742-6588 N1 - Corresponding author der OTH Regensburg: Philipp Stocker VL - 3104 IS - 1 PB - IOP Publishing ER - TY - JOUR A1 - Hantsch, Carolin A1 - Westner, Markus A1 - Matschi, Markus T1 - IT/OT-Konvergenz: Status-Quo und Umsetzungsempfehlungen JF - HMD Praxis der Wirtschaftsinformatik N2 - Organisationen machen große Anstrengungen zur Verbesserung ihrer Ambidextrie, d. h. ihrer Fähigkeit sowohl Exploitationsziele (z. B. Effizienz, Vorhersagbarkeit) als auch Explorationsziele (z. B. Anpassbarkeit, Innovation) zu erreichen. Obwohl gemäß der Praxisliteratur Technologie in Software-Projekten dabei eine zentrale Rolle spielen kann, gibt es kaum Forschung dazu, wie technologische Faktoren Ambidexterie in Software-Projekten beeinflussen. In dieser Studie untersuchen wir die Rolle dreier technologischer Faktoren: kontinuierliche Integration, Standardisierung und Microservice-Architektur. Die Ergebnisse einer Mehrinformanten-Umfrage in 95 Projekten in der Schweiz und Dänemark zeigen, dass kontinuierliche Integration und Standardisierung mit höherer Ambidexterie einhergehen, während der Zusammenhang zwischen Microservice-Architektur und Ambidextrie nicht signifikant ist. Unser Artikel geht über die existierende Forschung hinaus, indem er zeigt, dass kontinuierliche Integration und Standardisierung nicht nur Exploitation, sondern auch Exploration fördern können. Wir diskutieren auch Gründe für den insignifikanten Zusammenhang zwischen Microservice-Architektur und Ambidextrie. N2 - This study examines IT/OT Convergence in 31 predominantly large German companies. It presents an “IT/OT Governance Framework” as a specific model for successful convergence implementation. The analysis reveals a heterogeneous level of convergence maturity across the examined companies, the majority of which are at the beginning or in the implementation phase. Close cooperation between IT and OT is favored, but without IT completely taking over OT. An IT/OT tandem consisting of a CIO and a central OT responsible person is seen as the ideal way to take responsibility. Six specific recommendations were derived from the interviews and included in the IT/OT Governance Framework developed. These include ensuring top management support, using security as a driver, introducing a central OT responsible person, bringing IT and OT teams physically closer together, continuously demonstrating the added value of convergence, and taking a step-by-step approach to implementation. KW - IT/OT Convergence KW - Operational Technology KW - OT KW - Governance Y1 - 2024 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-77937 N1 - Corresponding author der OTH Regensburg: Markus Westner PB - Springer Nature ER - TY - JOUR A1 - Schmid, Michael T. A1 - Thiel, Charlotte T1 - Is it worth it? Potential for reducing the environmental impact of bitumen roofing membrane production JF - Recycling N2 - Between 51% and 72% of a bituminous roofing membrane used for structural water-proofing consists of organic material, predominantly bitumen - a derivative of crude oil refining - highlighting the strong dependence of this product on fossil resources. Considering that several tonnes of these membranes must be replaced every 30 to 50 years, substantial potential exists for emission reduction through the establishment of circular material systems. This study investigates this potential by analysing 26 Environmental Product Declarations (EPDs) and life cycle datasets from across Europe covering the period from 2007 to 2023. To ensure comparability, all data were normalised to a declared unit of 1 kg of roofing membrane. The reinforcement layers were categorised into glass and polyester & glass composites, and their differences were examined using Welch’s t-tests. Correlative analyses and linear as well as multiple regression models were then applied to explore relationships between environmental indicators and the shares of organic and mineral mass fractions. The findings reveal that renewable energy sources, although currently representing only a small share of total production energy, provide a major lever for reducing nearly all environmental impact categories. The type of reinforcement layer was also found to influence the demand for fossil resources, both materially and energetically. For most environmental indicators, only multiple regression models can explain at least 30% of the variance based on the proportions of organic and mineral inputs. Overall, the study underscores the crucial importance of high-quality, transparently documented product data for accurately assessing the sustainability of building products. It further demonstrates that substituting fossil energy carriers with renewable sources and optimising material efficiency can substantially reduce environmental burdens, provided that methodological consistency and clarity of indicator definitions are maintained. KW - bitumen sealing KW - bitumen recycling KW - circular construction KW - correlation analysis KW - LCA Y1 - 2025 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-86873 N1 - Corresponding author der OTH Regensburg: Michael Schmid VL - 10 IS - 6 PB - MDPI ER - TY - JOUR A1 - Bedbur, Stefan A1 - Kamps, Udo A1 - Schmiedt, Anja Bettina T1 - A flexible model of ordered random variables for non-metallic inclusions in steels and related statistical inference JF - Applied Mathematical Modelling N2 - In a data set of non-metallic inclusion sizes in samples from engineering steel, common order statistics fail to serve as a suitable model for ascendingly ordered measurements within single samples. Therefore, a flexible model of ordered random variables is proposed, which allows for changes of distributions described by model parameters. Joint maximum likelihood estimation of these parameters and the shape parameter of an underlying left-truncated Weibull distribution is considered, and a model test is developed for the null-hypothesis of common order statistics being an adequate model. To overcome small data situations, a link-function approach is examined in order to reduce the number of involved model parameters as well as to propose to use a link-function parameter as a material indicator. An asymptotic test is provided to check for the presence of a linear link function, and tests for hypotheses about two link-function parameters are studied. Moreover, the construction of simultaneous confidence regions for the link-function parameters as well as of confidence bands for the entire graph of the link function are presented. Throughout, the findings are applied to the real metallurgical data set. Similar problems and data structures arise in other fields of material science and applications such as geology. Y1 - 2026 U6 - https://doi.org/10.1016/j.apm.2025.116284 SN - 0307-904X N1 - Corresponding author der OTH Regensburg: Anja Bettina Schmiedt VL - 149 PB - Elsevier ER - TY - JOUR A1 - Schumm, Leon A1 - Brown, Tom A1 - Abdel-Khalek, Hazem A1 - Ueckerdt, Falko A1 - Sterner, Michael A1 - Fioriti, David A1 - Parzen, Max T1 - The impact of temporal hydrogen regulation on hydrogen exporters and their domestic energy transition JF - Nature Communications N2 - As global demand for green hydrogen rises, potential hydrogen exporters move into the spotlight. While exports can bring countries revenue, large-scale on-grid hydrogen electrolysis for export can profoundly impact domestic energy prices and energy-related emissions. Our investigation explores the interplay of hydrogen exports, domestic energy transition and temporal hydrogen regulation, employing a sector-coupled energy model in Morocco. We find substantial co-benefits of domestic carbon dioxide mitigation and hydrogen exports, whereby exports can reduce market-based costs for domestic electricity consumers while mitigation reduces costs for hydrogen exporters. However, increasing hydrogen exports in a fossil-dominated system can substantially raise market-based costs for domestic electricity consumers, but surprisingly, temporal matching of hydrogen production can lower these costs by up to 31% with minimal impact on exporters. Here, we show that this policy instrument can steer the welfare (re-)distribution between hydrogen exporting firms, hydrogen importers, and domestic electricity consumers and hereby increases acceptance among actors. KW - Energy Transition KW - Hydrogen regulation Y1 - 2025 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-84857 N1 - Die Preprint-Version ist ebenfalls in diesem Repositorium verzeichnet unter: https://opus4.kobv.de/opus4-oth-regensburg/7272 VL - 16 PB - Nature CY - London ER - TY - JOUR A1 - Schmiedt, Anja B. A1 - Empacher, Christina A1 - Kamps, Udo T1 - One- and two-sided prediction intervals for future Pareto record values with applications JF - Journal of Statistical Theory and Applications N2 - Based on upper record values in a series of observations over time from a Pareto distribution, an exact and several approximate one-sided and two-sided prediction intervals for the next record value (or for another future record value) to appear are studied and compared by means of an extensive simulation study. The performances of the prediction intervals are evaluated and recommendations are proposed for what method should be used in a given situation with respect to the form of the prediction interval on the one hand and to the tail behaviour on the other. The proposed methods are applied to insurance, environmental and sports data, where the respectively fitted Pareto distributions show a different tail behaviour. As a result, it is seen that although the number of observed record values in the presented real data applications is rather small, as it is usually the case, the selected prediction intervals are of practical use. KW - Interval prediction KW - Pareto distribution KW - Real data analyses KW - Record values KW - Simulation study Y1 - 2025 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-81605 SN - 2214-1766 N1 - Corresponding author der OTH Regensburg: Anja B. Schmiedt PB - Springer ER - TY - JOUR A1 - Dotter, Caroline A1 - Haug, Sonja A1 - Schnell, Rainer A1 - Raptis, Georgios A1 - Weber, Karsten T1 - Sharing health data for research purposes: results of a population survey in Germany JF - BMC health services research N2 - BACKGROUND: Increased use of health data has the potential to improve both health care and health policies. Several recent policy initiatives at the European and German legislative levels aim to increase the primary and secondary use of health data. However, little is known about general population views on health data access for research. Most studies are based on subsets defined by specific illnesses. METHODS: We commissioned a national computer-assisted dual-frame telephone survey (landline and mobile). Logit estimation models were used to identify predictors of willingness to provide access to health data to different organizations (universities in Germany, universities worldwide, German government organizations, pharmaceutical companies). RESULTS: A high willingness to share health data for research purposes is observed, depending on the specific data recipient. The willingness is highest for research at universities in Germany and German governmental organizations, and lowest regarding research by pharmaceutical companies. The main drivers for sharing health data are the level of trust in public institutions, the respondents' assessment of the seriousness and likelihood of data misuse, and the level of digital literacy. Age, gender, and level of education have small effects and do not determine the willingness to share health data for all organizations. CONCLUSION: We present evidence from a random sample of the German population. The results indicate widespread support among the population for providing access to health data for research purposes. Similar to findings in other countries, the willingness depends strongly on the recipient of the data. This paper evaluates the impact of various determinants - identified in previous qualitative and quantitative research - on the willingness of the German population to share health data. While previous studies have found that patients are generally more willing to share health data, we found that the presence of a medical precondition does not translate into respondents' unequivocal support for health data sharing. We identify privacy concerns, general trust, and digital literacy as key factors influencing the willingness to share health data. Therefore, policymakers and stakeholders need to ensure and communicate the necessary privacy protection measures to increase the willingness of the German population to share health data. Y1 - 2025 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-81622 N1 - Corresponding author der OTH Regensburg: Caroline Dotter VL - 25 PB - BMC ER - TY - CHAP A1 - Bugl, Benedikt A1 - Schneider, Viola I. A1 - Sehr, Armin T1 - Vertical Sound Localization: Precision and Robustness to Reverberation in a Large-Scale Study T2 - Proceedings of the 11th Convention of the European Acoustics Association Forum Acusticum / EuroNoise 2025 // Málaga, Spain ; 23-26. June 2025 N2 - Vertical sound localization, the ability to perceive the elevation of a sound source, is a fundamental aspect of human auditory perception, yet it remains far less understood than horizontal localization. Existing studies rely on small sample sizes, limiting the generalizability of findings. The presented study bridges that gap by examining vertical sound localization and precision in a cohort exceeding 150 participants, making it the largest investigation of its kind to date.Participants were exposed to broadband noise stimuli from various elevations under controlled anechoic conditions. The elevation localization error was measured by comparing perceived sound source elevations to actual positions of speakers of a curved array. Azimuth angles of arrival were altered between 0°, 45° and 90°. For a small group the experiment was repeated in echoic conditions, to gain insight in reverberation and reflection robustness of vertical sound localization.This large-scale study establishes benchmarks for vertical sound localization precision and robustness, advancing our understanding of human auditory spatial perception. These findings have implications for audio technology development, such as spatial audio rendering and hearing aid design, and lay the groundwork for further exploration into the neural and anatomical underpinnings of vertical localization. Y1 - 2025 SN - 978-84-87985-35-5 U6 - https://doi.org/10.61782/fa.2025.0953 SP - 3431 EP - 3434 PB - European Acoustics Association ER - TY - CHAP A1 - Galka, Stefan A1 - Meißner, Sebastian T1 - Simulation-Based Digital Twins for Internal Transport Systems T2 - Procedia Computer Science N2 - The increasing complexity of internal transport systems in industrial applications poses significant challenges for operational decision-making. This paper presents a simulation-based Digital Twin framework developed within the research project TwinTraSys to support the control of such systems. The framework is specifically tailored to the constraints of real-world IT infrastructures, requiring minimal transaction data, while enabling predictive analysis and dynamic scenario evaluation. It consists of a modular architecture divided into four core components: data provision, data preparation, simulation, and decision support. A dedicated simulation framework enables the automated generation of structural models and the integration of real-world operational control systems. The proposed approach has been validated in industrial settings and has demonstrated its ability to support resource planning and transport resource allocation through simulation-based experimentation and multi-criteria evaluation. This paper contributes to the practical advancement of Digital Twin applications in intralogistics by bridging the gap between theoretical models and real-world constraints. KW - Digital Twin KW - Intralogistics KW - Logistics KW - Operational Control KW - Simulation KW - Simulation-based Decision Support Y1 - 2025 U6 - https://doi.org/10.1016/j.procs.2025.12.016 N1 - Corresponding author der OTH Regensburg: Stefan Galka VL - 274 SP - 161 EP - 170 PB - Elsevier ER - TY - JOUR A1 - Afanasev, Anna A1 - Höfer, Philipp A1 - Holtmannspötter, Jens A1 - Zimmer, Felix A1 - Ehrlich, Ingo T1 - Development of a continuous fiber-reinforced 3D printing process with a 6-axis robot arm: Process design and equipment JF - The International Journal of Advanced Manufacturing Technology N2 - The utilisation of 3D printing processes in the fabrication of continuous fiber-reinforced composites confers a multitude of advantages, in particular flexible design based on structural requirements. In order to achieve greater flexibility, there is a necessity for 3D printing systems that allow for customisable material selection and fiber positioning. This paper presents the design of a robot-based 3D printing system that incorporates an in-situ impregnation line and flexibility regarding the machine code generation for fiber positioning. The development of the system enabled the attainment of an average fiber volume content of up to 37.12%. In the tensile tests, material characteristics up to E1 = 24.7 GPa and strength of up to RM1 = 0.51 GPa were determined. Y1 - 2026 U6 - https://doi.org/10.1007/s00170-025-17263-3 SN - 0268-3768 N1 - Corresponding author der OTH Regensburg: Anna Afanasev PB - Springer ER - TY - JOUR A1 - Wolfgramm, Alex A1 - Abb, Valerius A1 - Samp, Artur A1 - Samp, Rafal A1 - Hoffmann, Jens Christoph A1 - Müller, Rainer A1 - Kammler, Martin T1 - Structural and functional evolution of HKUST-1 nanoparticles induced by ball milling JF - Next Materials N2 - In this study, the effect of post-synthetic ball milling on the structural and functional properties of as-synthesized nanoparticles of the copper-based metal-organic framework (MOF) HKUST-1 was investigated for the first time. Nanoparticles were synthesized using sodium formate as a capping agent. The crystalline particles were subjected to a controlled ball milling process, which induced significant structural changes. Powder X-ray diffraction (PXRD) revealed a reduction in crystallite size from 91 nm to 21 nm and the introduction of microstrain, partially disrupting the MOF's long-range crystalline order, as evidenced by peak broadening and the diminished intensity of high-angle reflections. Particle morphology pre- and post-milling was further studied with scanning electron microscopy (SEM) imaging, verifying a narrow particle size distribution of ± 22 nm after milling. Fourier-transform infrared spectroscopy (FTIR) indicated protonation of carboxylate groups in the larger pores of the framework, likely due to moisture incorporation during milling. Brunauer-Emmett-Teller (BET) surface area analysis showed a substantial decrease in specific surface area from 521 m²/g to 226 m²/g, suggesting a partial collapse of the porous framework. We discuss the applicability of ball milling as a versatile means of post-synthetic approach to reduce MOF particle sizes, a key element in the preparation of MOF-based thin films using inks or polymers. KW - Ball milling KW - Copper-based metal-organic framework KW - HKUST-1 KW - Nitrogen adsorption Y1 - 2026 U6 - https://doi.org/10.1016/j.nxmate.2025.101544 N1 - Corresponding author der OTH Regensburg: Alex Wolfgramm VL - 10 PB - Elsevier ER -