TY - JOUR A1 - Wiesent, Lisa A1 - Spear, Ashley A1 - Nonn, Aida T1 - Computational analysis of the effects of geometric irregularities on the interaction of an additively manufactured 316L stainless steel stent and a coronary artery JF - Journal of the Mechanical Behavior of Biomedical Materials N2 - Customized additively manufactured (laser powder bed fused (L-PBF)) stents could improve the treatment of complex lesions by enhancing stent-artery conformity. However, geometric irregularities inherent for L-PBF stents are expected to influence not only their mechanical behavior but also their interaction with the artery. In this study, the influence of geometrical irregularities on stent-artery interaction is evaluated within a numerical framework. Thus, computed arterial stresses induced by a reconstructed L-PBF stent model are compared to those induced by the intended stent model (also representing a stent geometry obtained from conventional manufacturing processes) and a modified CAD stent model that accounts for the increased strut thickness inherent for L-PBF stents. It was found that, similar to conventionally manufactured stents, arterial stresses are initially related to the basic stent design/topology, with the highest stresses occurring at the indentations of the stent struts. Compared to the stent CAD model, the L-PBF stent induces distinctly higher and more maximum volume stresses within the plaque and the arterial wall. In return, the modified CAD model overestimates the arterial stresses induced by the L-PBF stent due to its homogeneously increased strut thickness and thus its homogeneously increased geometric stiffness compared with the L-PBF stent. Therefore, the L-PBF-induced geometric irregularities must be explicitly considered when evaluating the L-PBF stent-induced stresses because the intended stent CAD model underestimates the arterial stresses, whereas the modified CAD model overestimates them. The arterial stresses induced by the L-PBF stent were still within the range of values reported for conventional stents in literature, suggesting that the use of L-PBF stents is conceivable in principle. However, because geometric irregularities, such as protruding features from the stent surface, could potentially damage the artery or lead to premature stent failure, further improvement of L-PBF stents is essential. KW - Laser powder bed fusion (L-PBF) KW - Cardiovascular stents KW - Finite element analysis (FEA) KW - Geometrical imperfections KW - Stent-artery interaction Y1 - 2022 U6 - https://doi.org/10.1016/j.jmbbm.2021.104878 SN - 1751-6161 VL - 125 PB - Elsevier ER - TY - CHAP A1 - Xue, Lufeng A1 - Paredes, Marcelo A1 - Nonn, Aida A1 - Wierzbicki, Tomasz T1 - Modeling of Crack Propagation in Defective X100 Line Pipes T2 - ASME 2020 39th International Conference on Ocean, Offshore and Arctic Engineering: August 3-7, 2020, virtual, online N2 - A comprehensive experimental program is carried out to determine material parameters for fracture initiation and propagation in X100 pipeline steels. The quadratic Hill’48 yield function along with an isotropic hardening are used to describe plastic flow at large deformation and a phenomenological fracture criterion to predict fracture initiation. Fracture mechanics SENT specimens are used to calibrate post-initiation softening parameters necessary for ductile crack propagation in thick components. Once the material model parameters set is complete a final comparison is conducted with ring expansion test on same material. KW - Berg KW - Bruchmechanik KW - Pipeline KW - plastisches Fließen KW - Rissausbreitung KW - Versuchsprogramm KW - Werkstoffmodell KW - Werkstoffparameter Y1 - 2020 SN - 978-0-7918-8434-8 U6 - https://doi.org/10.1115/OMAE2020-18048 PB - American Society of Mechanical Engineers CY - New York ER - TY - JOUR A1 - Wiesent, Lisa A1 - Stocker, Felix A1 - Nonn, Aida T1 - Investigating the influence of geometric parameters on the deformation of laser powder bed fused stents using low-fidelity thermo-mechanical analysis JF - Materialia N2 - Maintaining dimensional accuracy is a major challenge of laser powder bed fusion (L-PBF) preventing its application for more complex and filigree L-PBF structures in industrial practice. Previous studies have shown that residual stresses and distortion of benchmark L-PBF components may be predicted by sequential thermo-mechanical analyses. However, the reliability of these analyses for more complex structures must be critically questioned, as comprehensive validation and sensitivity analyses are scarce. In this paper, we present a calibrated and validated low-fidelity sequential thermo-mechanical finite element analysis (FEA) of a tubular L-PBF lattice structure, i.e., an aortic stent, where pronounced local deformation is expected. As a first step, the finite element model was extensively calibrated using experimental data to ensure reproducibility of the simulation results. Thereupon, geometric features critical to the distortion of L-PBF lattice structures and measures to compensate for the distortion, such as inversion of the distorted L-PBF structure, were investigated. It was found that the distortion of the L-PBF lattice structures can be reduced, but not completely prevented, by increasing the strut angles, increasing the strut thickness, and decreasing the transition radius in the area of merging struts. FEA-based inversion of the numerically predicted deformed structure minimized distortion, resulting in the L-PBF aortic stent approximating the intended CAD geometry even with a small strut thickness. This work shows that low-fidelity sequential thermo-mechanical FEA can be used not only for the analysis and deformation compensation of reference structures, but also for the analysis of more complex filigree structures with pronounced local deformation. Y1 - 2023 U6 - https://doi.org/10.1016/j.mtla.2023.101774 VL - 28 PB - Elsevier ER - TY - JOUR A1 - Nonn, Aida A1 - Kiss, Bálint A1 - Pezeshkian, Weria A1 - Tancogne-Dejean, Thomas A1 - Cerrone, Albert R. A1 - Kellermayer, Miklos A1 - Bai, Yuanli A1 - Li, Wei A1 - Wierzbicki, Tomasz T1 - Inferring mechanical properties of the SARS-CoV-2 virus particle with nano-indentation tests and numerical simulations JF - Journal of the mechanical behavior of biomedical materials N2 - The pandemic caused by the SARS-CoV-2 virus has claimed more than 6.5 million lives worldwide. This global challenge has led to accelerated development of highly effective vaccines tied to their ability to elicit a sustained immune response. While numerous studies have focused primarily on the spike (S) protein, less is known about the interior of the virus. Here we propose a methodology that combines several experimental and simulation techniques to elucidate the internal structure and mechanical properties of the SARS-CoV-2 virus. The mechanical response of the virus was analyzed by nanoindentation tests using a novel flat indenter and evaluated in comparison to a conventional sharp tip indentation. The elastic properties of the viral membrane were estimated by analytical solutions, molecular dynamics (MD) simulations on a membrane patch and by a 3D Finite Element (FE)-beam model of the virion's spike protein and membrane molecular structure. The FE-based inverse engineering approach provided a reasonable reproduction of the mechanical response of the virus from the sharp tip indentation and was successfully verified against the flat tip indentation results. The elastic modulus of the viral membrane was estimated in the range of 7-20 MPa. MD simulations showed that the presence of proteins significantly reduces the fracture strength of the membrane patch. However, FE simulations revealed an overall high fracture strength of the virus, with a mechanical behavior similar to the highly ductile behavior of engineering metallic materials. The failure mechanics of the membrane during sharp tip indentation includes progressive damage combined with localized collapse of the membrane due to severe bending. Furthermore, the results support the hypothesis of a close association of the long membrane proteins (M) with membrane-bound hexagonally packed ribonucleoproteins (RNPs). Beyond improved understanding of coronavirus structure, the present findings offer a knowledge base for the development of novel prevention and treatment methods that are independent of the immune system. Y1 - 2023 U6 - https://doi.org/10.1016/j.jmbbm.2023.106153 SN - 1751-6161 VL - 148 PB - Elsevier ER - TY - JOUR A1 - Cerrone, Albert R. A1 - Nonn, Aida A1 - Hochhalter, Jacob D. A1 - Bomarito, Geoffrey F. A1 - Warner, J. E. A1 - Carter, Bruce J. T1 - Predicting failure of the Second Sandia Fracture Challenge geometry with a real-world, time constrained, over-the-counter methodology JF - International Journal of Fracture N2 - An over-the-counter methodology to predict fracture initiation and propagation in the challenge specimen of the Second Sandia Fracture Challenge is detailed herein. This pragmatic approach mimics that of an engineer subjected to real-world time constraints and unquantified uncertainty. First, during the blind prediction phase of the challenge, flow and failure locus curves were calibrated for Ti–6Al–4V with provided tensile and shear test data for slow (0.0254 mm/s) and fast (25.4 mm/s) loading rates. Thereafter, these models were applied to a 3D finite-element mesh of the non-standardized challenge geometry with nominal dimensions to predict, among other items, crack path and specimen response. After the blind predictions were submitted to Sandia National Labs, they were improved upon by addressing anisotropic yielding, damage initiation under shear dominance, and boundary condition selection. KW - Ti–6Al–4V KW - Failure locus curve KW - Sandia Fracture Challenge KW - Anisotropic yielding Y1 - 2016 U6 - https://doi.org/10.1007/s10704-016-0086-x VL - 198 IS - 1-2 SP - 117 EP - 126 ER - TY - CHAP A1 - Romano, Marco A1 - Hoinkes, Carl J. J. A1 - Ehrlich, Ingo A1 - Höcherl, Johannes A1 - Gebbeken, Norbert ED - Meran, C. T1 - Influence of the impactor on the experimentally determined energy dissipation properties of fiber-reinforced plastics with hybrid layups under high velocity impact loads T2 - Proceeding of the 15th International Materials Symposium (IMSP´2014), Pamukkale University (Denizli, Turkey), 15./17. October 2014 Y1 - 2014 SP - 650 EP - 664 ER - TY - CHAP A1 - Hoinkes, Carl J. J. A1 - Romano, Marco A1 - Ehrlich, Ingo A1 - Höcherl, Johannes A1 - Gebbeken, Norbert ED - Ziemann, Olaf ED - Mottok, Jürgen ED - Pforr, Johannes T1 - Investigation of fibre reinforced plastics with monolithic and hybrid stacking sequences under high-velocity impact loads T2 - Applied Research Conference 2014 - ARC 2014, 5th July 2014, Ingolstadt Y1 - 2014 PB - Shaker CY - Aachen ER - TY - JOUR A1 - Cerrone, Albert R. A1 - Wawrzynek, Paul A1 - Nonn, Aida A1 - Paulino, Glaucio H. A1 - Ingraffea, Anthony R. T1 - Implementation and verification of the Park–Paulino–Roesler cohesive zone model in 3D JF - Engineering Fracture Mechanics N2 - The Park–Paulino–Roesler (PPR) potential-based model is a cohesive constitutive model formulated to be consistent under a high degree of mode-mixity. Herein, the PPR’s generalization to three-dimensions is detailed, its implementation in a finite element framework is discussed, and its use in single-core and high performance computing (HPC) applications is demonstrated. The PPR model is shown to be an effective constitutive model to account for crack nucleation and propagation in a variety of applications including adhesives, composites, linepipe steel, and microstructures. KW - Cohesive zone modeling KW - Cohesive element KW - Intergranular fracture KW - Finite element analysis KW - PPR potential-based model Y1 - 2014 U6 - https://doi.org/10.1016/j.engfracmech.2014.03.010 VL - 120 SP - 26 EP - 42 ER - TY - CHAP A1 - Eisenried, Michael A1 - Romano, Marco A1 - Jungbauer, Bastian A1 - Ehrlich, Ingo A1 - Gebbeken, Norbert ED - Ziemann, Olaf ED - Bogner, Werner ED - Mottok, Jürgen T1 - Influence of parameters of the production process on the material quality of unidirectionally reinforced prepregs T2 - Applied Research Conference 2013, ARC 2013 ; 17th and 18th October 2013, Deggendorf Y1 - 2013 SP - 70 EP - 75 PB - Shaker CY - Aachen ER - TY - CHAP A1 - Lindner, Matthias A1 - Berndt, Dominik A1 - Tschurtschenthal, Karl A1 - Ehrlich, Ingo A1 - Jungbauer, Bastian A1 - Schreiner, Rupert A1 - Pipa, Andrei V. A1 - Hink, Rüdiger A1 - Foest, Rüdiger A1 - Brandenburg, Ronny A1 - Neuwirth, Daniel A1 - Karpen, Norbert A1 - Bonaccurso, Elmar A1 - Weichwald, Robert A1 - Max, Alexander A1 - Caspari, Ralf T1 - Aircraft Icing Mitigation by DBD-based Micro Plasma Actuators T2 - AIAA AVIATION 2020 FORUM: June 15-19, 2020 N2 - We present the application of plasma actuators as a technology for ice prevention at airfoils. The miniaturized dielectric barrier discharge (DBD) plasma actuators (PA) were fabricated by means of microelectromechanical systems (MEMS). We elucidate how to make the actuator samples scalable and applicable to any desired shape by the use of flexible inorganic zirconia substrates. For this purpose, we applied our developed embedding method to integrate the micro actuators in modern carbon/glass fiber reinforced polymer (CFRP/GFRP) materials. Next, the embedded actuator samples were mounted on a mechanical air profile-like fixture and placed in the icing wind tunnel iCORE. The samples were tested in rime ice conditions at temperatures of -15 to -20° C and air speeds up to 30 m/s. Unlike other groups we used a thin film zirconia substrate as dielectric for the plasma actuator. Due to the low substrate thickness of just 150 µm, an operating voltage of 2 kVRMS is already sufficient enough for a stable plasma formation. The experiments show that the operated actuator was able to prevent the ice formation and first indications of a De-icing function were also found. Hence, we show that it is feasible to realize an anti-icing system with zirconia-based plasma actuators operated at lower voltages compared to conventional ones. Y1 - 2020 U6 - https://doi.org/10.2514/6.2020-3243 ER - TY - CHAP A1 - Lindner, Matthias A1 - Berndt, Dominik A1 - Jungbauer, Bastian A1 - Ehrlich, Ingo A1 - Schreiner, Rupert A1 - Pipa, Andrei V. A1 - Hink, Rüdiger A1 - Foest, Rüdiger A1 - Brandenburg, Ronny A1 - Max, Alexander A1 - Caspari, Ralf T1 - Fabrication, surface integration and testing of miniaturized dielectric barrier discharge plasma actuators for active flow control applications T2 - AIAA Aviation 2019 Forum, 17-21 June 2019, Dallas, Texas Y1 - 2019 U6 - https://doi.org/10.2514/6.2019-2998 ER - TY - CHAP A1 - Niedernhuber, Michal A1 - Ehrlich, Ingo A1 - Holtmannspötter, Jens ED - Ziemann, Olaf ED - Mottok, Jürgen ED - Pforr, Johannes T1 - Fiber-Oriented Repair of Fiber Reinforced Plastics: Investigations on Tensile Specimens T2 - 4th Applied Research Conference - ARC 2014, 5th July 2014, Ingolstadt Y1 - 2014 SP - 298 EP - 302 PB - Shaker CY - Aachen ER - TY - CHAP A1 - Pongratz, Christian A1 - Ehrlich, Ingo ED - Mottok, Jürgen ED - Reichenberger, Marcus ED - Stolle, Reinhard T1 - Structural Dynamic Analysis of Thin Composite Plates Using Noncontact Measurement and Excitation T2 - Applied Research Conference 2016 - ARC 2016, Augsburg, 24 June 2016 Y1 - 2016 SN - 978-3-86460-494-2 SP - 351 EP - 358 PB - Pro Business Verlag CY - Berlin ER - TY - RPRT A1 - Pongratz, Christian A1 - Ehrlich, Ingo ED - Baier, Wolfgang T1 - DampSIM: Lebensdauerüberwachung von faserverstärkten Kunststoffen auf Basis der strukurdynamischen Werkstoffdämpfung T2 - Forschungsbericht 2017 / Ostbayerische Technische Hochschule Regensburg Y1 - 2017 UR - https://doi.org/10.35096/othr/pub-1383 SN - 978-3-9818209-3-5 SP - 62 EP - 63 ER -