TY - JOUR A1 - Winter, Lina A1 - Artinger, Annalena A1 - Böck, Hendrik A1 - Ramakrishnan, Vignesh A1 - Reible, Bruno A1 - Albin, Jan A1 - Schüffler, Peter J. A1 - Raptis, Georgios A1 - Brochhausen, Christoph T1 - Developing a smart and scalable tool for histopathological education—PATe 2.0 JF - Journal of Pathology Informatics N2 - Digital microscopy plays a crucial role in pathology education, providing scalable and standardized access to learning resources. In response, we present PATe 2.0, a scalable redeveloped web-application of the former PATe system from 2015. PATe 2.0 was developed using an agile, iterative process and built on a microservices architecture to ensure modularity, scalability, and reliability. It integrates a modern web-based user interface optimized for desktop and tablet use and automates key workflows such as whole-slide image uploads and processing. Performance tests demonstrated that PATe 2.0 significantly reduces tile request times compared to PATe, despite handling larger tiles. The platform supports open formats like DICOM and OpenSlide, enhancing its interoperability and adaptability across institutions. PATe 2.0 represents a robust digital microscopy solution in pathology education enhancing usability, performance, and flexibility. Its design enables future integration of research algorithms and highlights it as a pivotal tool for advancing pathology education and research. Y1 - 2026 U6 - https://doi.org/10.1016/j.jpi.2025.100535 SN - 2153-3539 VL - 20 PB - Elsevier ER - TY - INPR A1 - Cenko, Egidia A1 - Weimann, Thure Georg A1 - Raptis, Georgios T1 - Navigating the DiGA Jungle: A Taxonomy and Archetypal Framework of the German Digital Therapeutics Landscape N2 - Digital therapeutics (DTx) are patient-facing apps designed to support individuals in their daily lives. Therefore, they have thepotential to revolutionize healthcare by empowering and engaging patients to become active players in their own care. Despitethe increasing adoption of DTx in national healthcare systems, research on their design remains limited. The present studyintroduces “DiGATax”, a taxonomy designed to categorize and analyze DTx, including perspectives on content, interventiondelivery logic and technology, as well as the patient’s interface, consolidating and expanding upon prior taxonomic work.Based on n = 44 applications retrieved from the German DiGA directory that demonstrated positive health outcomes, thetaxonomy is supported by empirical evidence. Additionally, the study contributes by presenting an archetype frameworkof DTx derived from a taxonomy-based cluster analysis. Further analyses offer insights into specific combinations of DTxcharacteristics across archetypes, the user interface as a key factor in their acceptance, and potential links between DTxdesign and health-related and user engagement outcomes. By offering new insights into DTx design, this study contributestowards more organized research and reporting, ultimately paving the way for the development of effective solutions. It alsomarks a further step towards Meta-DTx, which aim to align patient care for multimorbid patients under one umbrella. KW - Archetypes KW - Digital Behavior Change Interventions KW - Digital Therapeutics KW - mHealth KW - Taxonomy Y1 - 2025 U6 - https://doi.org/10.64898/2025.12.30.25343225 ER -