TY - JOUR A1 - Prantl, Lukas A1 - Eigenberger, Andreas A1 - Gehmert, Sebastian A1 - Haerteis, Silke A1 - Aung, Thiha A1 - Rachel, Reinhard A1 - Jung, Ernst Michael A1 - Felthaus, Oliver T1 - Enhanced Resorption of Liposomal Packed Vitamin C Monitored by Ultrasound JF - Journal of Clinical Medicine N2 - Vitamin C is an essential nutrient for humans and is involved in a plethora of health-related functions. Several studies have shown a connection between vitamin C intake and an improved resistance to infections that involves the immune system. However, the body cannot store vitamin C and both the elevated oral intake, and the intravenous application have certain disadvantages. In this study, we wanted to show a new formulation for the liposomal packaging of vitamin C. Using freeze etching electron microscopy, we show the formed liposomes. With a novel approach of post-processing procedures of real-time sonography that combines enhancement effects by contrast-like ultrasound with a transducer, we wanted to demonstrate the elevated intestinal vitamin C resorption on four participants. With the method presented in this study, it is possible to make use of the liposomal packaging of vitamin C with simple household materials and equipment for intake elevation. For the first time, we show the enhanced resorption of ingested liposomes using microbubble enhanced ultrasound imaging. KW - ASCORBIC-ACID KW - CEUS KW - CONTRAST AGENT KW - CULTURES KW - DEFICIENCY KW - enhanced resorption KW - GULO KW - immune system KW - liposomal packing KW - MITOCHONDRIAL DYSFUNCTION KW - OXIDATIVE STRESS KW - PHOSPHATIDYLCHOLINE KW - sonography KW - vitamin C Y1 - 2020 U6 - https://doi.org/10.3390/jcm9061616 VL - 9 IS - 6 SP - 1 EP - 12 PB - MDPI CY - Basel ER - TY - JOUR A1 - Huss, Sorin A. A1 - Stein, Oliver T1 - A Novel Design Flow for a Security-Driven Synthesis of Side-Channel Hardened Cryptographic Modules JF - Journal of Low Power Electronics and Applications N2 - Over the last few decades, computer-aided engineering (CAE) tools have been developed and improved in order to ensure a short time-to-market in the chip design business. Up to now, these design tools do not yet support an integrated design strategy for the development of side-channel-resistant hardware implementations. In order to close this gap, a novel framework named AMASIVE (Adaptable Modular Autonomous SIde-Channel Vulnerability Evaluator) was developed. It supports the designer in implementing devices hardened against power attacks by exploiting novel security-driven synthesis methods. The article at hand can be seen as the second of the two contributions that address the AMASIVE framework. While the first one describes how the framework automatically detects vulnerabilities against power attacks, the second one explains how a design can be hardened in an automatic way by means of appropriate countermeasures, which are tailored to the identified weaknesses. In addition to the theoretical introduction of the fundamental concepts, we demonstrate an application to the hardening of a complete hardware implementation of the block cipher PRESENT. KW - side-channel analysis KW - secure CAE design Y1 - 2017 U6 - https://doi.org/10.3390/jlpea7010004 SN - 2079-9268 VL - 7 IS - 1 PB - MDPI CY - Basel ER - TY - CHAP A1 - Baumann, Timo A1 - Bangalore, Srinivas A1 - Hirschberg, Julia ED - Federico, Marcello ED - Stüker, Sebastian ED - Yvon, François T1 - Towards Simultaneous Interpreting: The Timing of Incremental Machine Translation and Speech Synthesis T2 - Proceedings of the 11th International Workshop on Spoken Language Translation. Papers. Lake Tahoe, December 4th and 5th, 2014 N2 - In simultaneous interpreting, human experts incrementally construct and extend partial hypotheses about the source speaker’s message, and start to verbalize a corresponding message in the target language, based on a partial translation – which may have to be corrected occasionally. They commence the target utterance in the hope that they will be able to finish understanding the source speaker’s message and determine its translation in time for the unfolding delivery. Of course, both incremental understanding and translation by humans can be garden-pathed, although experts are able to optimize their delivery so as to balance the goals of minimal latency, translation quality and high speech fluency with few corrections. We investigate the temporal properties of both translation input and output to evaluate the tradeoff between low latency and translation quality. In addition, we estimate the improvements that can be gained with a tempo-elastic speech synthesizer. KW - incremental processing KW - speech synthesis KW - timing KW - simultaneous interpreting Y1 - 2014 UR - https://aclanthology.org/2014.iwslt-papers.2.pdf SP - 163 EP - 168 ER - TY - JOUR A1 - Meyer-Sickendiek, Burkhard A1 - Hussein, Hussein A1 - Baumann, Timo T1 - Towards the Creation of a Poetry Translation Mapping System JF - Archives of Data Science, Series A N2 - The translation of poetry is a complex, multifaceted challenge: the translated text should communicate the same meaning, similar metaphoric expressions, and also match the style and prosody of the original poem. Research on machine poetry translation is existing since 2010, but for four reasons it is still rather insufficient: 1. The few approaches existing completely lack any knowledge about current developments in both lyric theory and translation theory. 2. They are based on very small datasets. 3. They mostly ignored the neural learning approach that superseded the long-standing dominance of phrase-based approaches within machine translation. 4. They have no concept concerning the pragmatic function of their research and the resulting tools. Our paper describes how to improve the existing research and technology for poetry translations in exactly these four points. With regards to 1) we will describe the “Poetics of Translation”. With regards to 2) we will introduce the Worlds largest corpus for poetry translations from lyrikline. With regards to 3) we will describe first steps towards a neural machine translation of poetry. With regards to 4) we will describe first steps towards the development of a poetry translation mapping system. Y1 - 2018 U6 - https://doi.org/10.5445/KSP/1000087327/21 SN - 2363-9881 VL - 5 IS - 1 SP - 1 EP - 15 PB - Towards the Creation of a Poetry Translation Mapping System ER - TY - JOUR A1 - Weber, Felix A1 - Borchsenius, Fredrik A1 - Distl, Johann A1 - Braun, Christian T1 - Performance of Numerically Optimized Tuned Mass Damper with Inerter (TMDI) JF - Applied Sciences N2 - In recent years, the Tuned Mass Damper with inerter (TMDI) has received significant attention. The inerter is defined to exert a force that is in proportion to the relative acceleration of the two inerter terminals. Here, two TMDI topologies are investigated. The conventional topology is given by the inerter being in parallel to the spring and viscous damper of the TMDI. The other topology is the serial arrangement of spring, inerter and viscous damper being in parallel to the stiffness of the mass spring oscillator of the TMDI. While the first topology intends to increase the inertial force of the TMDI, the second topology aims at producing an additional degree of freedom. The considered TMDI concepts are simulated for harmonic and random excitations, with parameters set according to those described in the literature and with numerically optimized parameters which minimize the primary structure displacement response. The classical TMD is used as a benchmark. The findings are twofold. The conventional TMDI with typical inertance ratio of 1% and the very small value of 0.02% performs significantly worse than the classical TMD with the same mass ratio. In contrast, the TMDI with an additional degree of freedom can improve the mitigation of the primary structure if the inertance ratio is set very small and if the TMDI parameters are numerically optimized. KW - damping KW - inerter KW - optimization KW - TMD KW - TMDI KW - vibration Y1 - 2022 U6 - https://doi.org/10.3390/app12126204 VL - 12 IS - 12 SP - 1 EP - 15 PB - MDPI CY - Basel ER - TY - CHAP A1 - Baumann, Timo A1 - Meyer-Sickendiek, Burkhard ED - Krauwer, Steven ED - Fišer, Darja T1 - Deep Learning meets Post-modern Poetry T2 - TwinTalks 2020: Understanding and Facilitating Collaboration in Digital Humanities 2020, proceedings of the Twin Talks 2 and 3 workshops at DHN 2020 and DH 2020, Ottawa Canada and Riga Latvia, July 23 and October 20, 2020 N2 - We summarize our project Rhythmicalizer in which we analyze a corpus of post-modern poetry in a combination of qualitative hermeneutical and computational methods, as we have run the project over the course of the past three years (and preparing it for some time before that). Interdisciplinary work is always challenging and we here focus on some of the highlights of our collaboration. KW - Literary Studies KW - Machine Learning KW - Meta-Research Y1 - 2020 UR - http://ceur-ws.org/Vol-2717/paper03.pdf SN - 1613-0073 SP - 30 EP - 36 PB - RWTH Aachen ER - TY - JOUR A1 - Bayerstadler, Andreas A1 - Becquin, Guillaume A1 - Binder, Julia A1 - Botter, Thierry A1 - Ehm, Hans A1 - Ehmer, Thomas A1 - Erdmann, Marvin A1 - Gaus, Norbert A1 - Harbach, Philipp A1 - Hess, Maximilian A1 - Klepsch, Johannes A1 - Leib, Martin A1 - Luber, Sebastian A1 - Luckow, Andre A1 - Mansky, Maximilian A1 - Mauerer, Wolfgang A1 - Neukart, Florian A1 - Niedermeier, Christoph A1 - Palackal, Lilly A1 - Pfeiffer, Ruben A1 - Polenz, Carsten A1 - Sepulveda, Johanna A1 - Sievers, Tammo A1 - Standen, Brian A1 - Streif, Michael A1 - Strohm, Thomas A1 - Utschig-Utschig, Clemens A1 - Volz, Daniel A1 - Weiss, Horst A1 - Winter, Fabian T1 - Industry quantum computing applications JF - EPJ Quantum Technology N2 - Quantum computing promises to overcome computational limitations with better and faster solutions for optimization, simulation, and machine learning problems. Europe and Germany are in the process of successfully establishing research and funding programs with the objective to dvance the technology’s ecosystem and industrialization, thereby ensuring digital sovereignty, security, and competitiveness. Such an ecosystem comprises hardware/software solution providers, system integrators, and users from research institutions, start-ups, and industry. The vision of the Quantum Technology and Application Consortium (QUTAC) is to establish and advance the quantum computing ecosystem, supporting the ambitious goals of the German government and various research programs. QUTAC is comprised of ten members representing different industries, in particular automotive manufacturing, chemical and pharmaceutical production, insurance, and technology. In this paper, we survey the current state of quantum computing in these sectors as well as the aerospace industry and identify the contributions of QUTAC to the ecosystem. We propose an application-centric approach for the industrialization of the technology based on proven business impact. This paper identifies 24 different use cases. By formalizing high-value use cases into well-described reference problems and benchmarks, we will guide technological progress and eventually commercialization. Our results will be beneficial to all ecosystem participants, including suppliers, system integrators, software developers, users, policymakers, funding program managers, and investors. KW - Benchmarks KW - Industry application KW - Quantum computing KW - QUTAC KW - Reference problems Y1 - 2021 U6 - https://doi.org/10.1140/epjqt/s40507-021-00114-x VL - 8 SP - 1 EP - 17 PB - Springer ER - TY - JOUR A1 - Pit, Sabrina A1 - Fisk, Malcolm A1 - Freihaut, Winona A1 - Akintunde, Fashola A1 - Aloko, Bamidele A1 - Berge, Britta A1 - Burmeister, Anne A1 - Ciacâru, Adriana A1 - Deller, Jürgen A1 - Dulmage, Rae A1 - Han, Tae Hwa A1 - Hao, Qiang A1 - Honeyman, Peter A1 - Huber, Peter C. A1 - Linner, Thomas A1 - Lundberg, Stefan A1 - Nwamara, Mofoluwaso A1 - Punpuing, Kamolpun A1 - Schramm, Jennifer A1 - Yamada, Hajime A1 - Yap, Jason C. H. T1 - COVID-19 and the ageing workforce: global perspectives on needs and solutions across 15 countries JF - International Journal for Equity in Health volume N2 - BACKGROUND: COVID-19 has a direct impact on the employment of older people. This adds to the challenge of ageism. The World Health Organization has started a worldwide campaign to combat ageism and has called for more research and evidence-based strategies that have the potential to be scaled up. This study specifically aims to identify solutions to combat the adverse effects of COVID-19 on the global ageing workforce. METHODS: We present 15 case studies from different countries and report on what those countries are doing or not doing to address the impact of COVID-19 on ageing workers. RESULTS: We provide examples of how COVID-19 influences older people's ability to work and stay healthy, and offer case studies of what governments, organizations or individuals can do to help ensure older people can obtain, maintain and, potentially, expand their current work. Case studies come from Australia, Austria, Canada, China, Germany, Israel, Japan, Nigeria, Romania, Singapore, Sweden, South Korea, Thailand, United Kingdom (UK), and the United States (US). Across the countries, the impact of COVID-19 on older workers is shown as widening inequalities. A particular challenge has arisen because of a large proportion of older people, often with limited education and working in the informal sector within rural areas, e.g. in Nigeria, Thailand and China. Remedies to the particular disadvantage experienced by older workers in the context of COVID are presented. These range from funding support to encouraging business continuity, innovative product and service developments, community action, new business models and localized, national and international actions. The case studies can be seen as frequently fitting within strategies that have been proven to work in reducing ageism within the workplace. They include policy and laws that have increased benefits to workers during lockdowns (most countries); educational activities such as coaching seniorpreneurship (e,g, Australia); intergenerational contact interventions such as younger Thai people who moved back to rural areas and sharing their digital knowledge with older people and where older people reciprocate by teaching the younger people farming knowledge. CONCLUSION: Global sharing of this knowledge among international, national and local governments and organizations, businesses, policy makers and health and human resources experts will further understanding of the issues that are faced by older workers. This will facilitate the replication or scalability of solutions as called for in the WHO call to combat ageism in 2021. We suggest that policy makers, business owners, researchers and international organisations build on the case studies by investing in evidence-based strategies to create inclusive workplaces. Such action will thus help to challenge ageism, reduce inequity, improve business continuity and add to the quality of life of older workers. KW - Aged KW - Aging KW - Communicable Disease Control KW - COVID-19 KW - Humans KW - Quality of Life KW - SARS-CoV-2 KW - United States KW - Workforce Y1 - 2021 U6 - https://doi.org/10.1186/s12939-021-01552-w VL - 20 SP - 1 EP - 22 PB - Springer Nature ER - TY - JOUR A1 - Göppel, Simon A1 - Frikel, Jürgen A1 - Haltmeier, Markus T1 - Feature Reconstruction from Incomplete Tomographic Data without Detour JF - Mathematics N2 - In this paper, we consider the problem of feature reconstruction from incomplete X-ray CT data. Such incomplete data problems occur when the number of measured X-rays is restricted either due to limit radiation exposure or due to practical constraints, making the detection of certain rays challenging. Since image reconstruction from incomplete data is a severely ill-posed (unstable) problem, the reconstructed images may suffer from characteristic artefacts or missing features, thus significantly complicating subsequent image processing tasks (e.g., edge detection or segmentation). In this paper, we introduce a framework for the robust reconstruction of convolutional image features directly from CT data without the need of computing a reconstructed image first. Within our framework, we use non-linear variational regularization methods that can be adapted to a variety of feature reconstruction tasks and to several limited data situations. The proposed variational regularization method minimizes an energy functional being the sum of a feature dependent datafitting term and an additional penalty accounting for specific properties of the features. In our numerical experiments, we consider instances of edge reconstructions from angular under-sampled data and show that our approach is able to reliably reconstruct feature maps in this case. KW - Computed tomography KW - Radon transform KW - reconstruction KW - limited data KW - sparse data KW - feature reconstruction, KW - edge detection Y1 - 2022 U6 - https://doi.org/10.3390/math10081318 VL - 10 IS - 8 PB - MDPI ER - TY - JOUR A1 - Christ, Andreas A1 - Brecht, Benjamin A1 - Mauerer, Wolfgang A1 - Silberhorn, Christine T1 - Theory of quantum frequency conversion and type-II parametric down-conversion in the high-gain regime JF - New Journal of Physics N2 - Frequency conversion (FC) and type-II parametric down-conversion (PDC) processes serve as basic building blocks for the implementation of quantum optical experiments: type-II PDC enables the efficient creation of quantum states such as photon-number states and Einstein–Podolsky–Rosen (EPR)-states. FC gives rise to technologies enabling efficient atom–photon coupling, ultrafast pulse gates and enhanced detection schemes. However, despite their widespread deployment, their theoretical treatment remains challenging. Especially the multi-photon components in the high-gain regime as well as the explicit time-dependence of the involved Hamiltonians hamper an efficient theoretical description of these nonlinear optical processes. In this paper, we investigate these effects and put forward two models that enable a full description of FC and type-II PDC in the high-gain regime. We present a rigorous numerical model relying on the solution of coupled integro-differential equations that covers the complete dynamics of the process. As an alternative, we develop a simplified model that, at the expense of neglecting time-ordering effects, enables an analytical solution. While the simplified model approximates the correct solution with high fidelity in a broad parameter range, sufficient for many experimental situations, such as FC with low efficiency, entangled photon-pair generation and the heralding of single photons from type-II PDC, our investigations reveal that the rigorous model predicts a decreased performance for FC processes in quantum pulse gate applications and an enhanced EPR-state generation rate during type-II PDC, when EPR squeezing values above 12 dB are considered. Y1 - 2013 U6 - https://doi.org/10.1088/1367-2630/15/5/053038 VL - 15 IS - 5 PB - IOP ER -