TY - GEN A1 - Auer, Simon A1 - Reinker, Lukas A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Comparing calculated and measured muscle activity of thigh muscles in dynamic motion. T2 - 27th Congress of the European Society of Biomechanics, 26 - 29 June 2022, Porto, Portugal Y1 - 2022 UR - https://drive.google.com/uc?id=1RBguxyHZE-Wr2y6ktOWK06_3lQg2M9Rb&export=download&confirm=t SP - 640 ER - TY - GEN A1 - Melzner, Maximilian A1 - Pfeifer, Christian A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Muskuloskeletal analysis of elbow stability for common injury patterns T2 - 27th Congress of the European Society of Biomechanics, 26 - 29 June 2022, Porto, Portugal Y1 - 2022 UR - https://drive.google.com/uc?id=1RBguxyHZE-Wr2y6ktOWK06_3lQg2M9Rb&export=download&confirm=t SP - 654 ER - TY - GEN A1 - Eger, Maximilian A1 - Bergstraesser, Marcel A1 - Dendorfer, Sebastian A1 - Lenich, Andreas A1 - Pfeifer, Christian T1 - Influence of radial head prosthetic design on humeroradial stability: Validation of a test rig therefore T2 - DOKU2022, Deutscher Kongress für Orthopädie und Unfallchirurgie, 25.-28. 10.2022, Berlin KW - radial head prostheses KW - humeroradial stability KW - radial head arthroplasty KW - subluxation Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0183-22dkou6115 PB - German Medical Science GMS Publishing House CY - Düsseldorf ER - TY - GEN A1 - Birkenmaier, Clemens A1 - Krenkel, Lars A1 - Lehle, Karla T1 - Linking flow conditions in membrane oxygenators to arrangements of multimeric von-Willebrand-factor as indication for coagulation T2 - World Congress of Biomechanics 2018, Convention Centre Dublin, 8.-12. Juli 2018 N2 - Introduction Shear induced multimerisation of von-Willebrand-factor (vWF) is supposed to play an important role in coagulation inside extracorporeal membrane oxygenators. However, there is no proof that links observed vWF structures to computed or measured flow conditions. Methods The structures of multimeric vWF fibers, observed in clinically used membrane oxygenators is examined using immunofluorescence microscopy (IFM) using Carstairs’ staining method (positive ethics committee vote). The flow around the membrane fibres inside the oxygenator is investigated in terms of shear rate, wall shear velocity and streamlines by using CFD (RANS, Carreau-Yasuda viscosity, geometry remodelled after high-resolution µCT-scans). By interpreting the histological and numerical results in this common context, indications for shear induced coagulation mechanisms can be identified. Results The fibre structures of multimeric vWF build regular but not exactly symmetric formations around the contact face (CF) between the crosswise stacked oxygenator fibres (OF), see fig.1B, vWF marked red. Annular around the CF arranged, cells are likely to be found, see fig.1B, nuclei marked blue. The computed streamlines around the OF show attached flow around the circular fibres. However, the irregular arrangement of real OF produce considerable cross flow between the interconnected neighbouring channels, in contrast to previous 2D-simulations. Thus, the CF are washed around closely by blood, also from neighbouring channels. The wall shear velocity streamlines form regular, slightly asymmetric shapes around the contact faces. The occurring maximum shear rates are in the range of 1,000 1/s. Discussion The shapes of vWF structures found in clinically used oxygenators match the computational results in terms of wall shear velocity and streamlines well. The accumulation of cells close to the CF can also be explained by fluid mechanics, as there are small shear gradients and slow velocities. However, occurring shear rates between OFs are too low to trigger multimerisation of vWF. That raises the question where in the circuit the actual activation of vWF is started and how, at least partly chained, vWF multimeres are attracted towards the OF surface. A next step will be the investigation of the actual shear rate triggered (or mediated) multimerisation of vWF. Towards this end, microfluidic experiments with shear triggered coagulation will be performed. Also of big interest is the computation of the flow situation in the oxygenator in proximity to chaining threads, which have been ignored in computations so far. However, first a realistic representation of the effective viscosity in computations is needed, which is not available yet. Y1 - 2018 ER - TY - GEN A1 - Kögler, Michael A1 - Ismail, Khaled M. A1 - Rusavy, Zdenek A1 - Kalis, Vladimir A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Influence of bed height and stance on accoucheurs lower back and glenohumeral load during simulated childbirth T2 - 31st meeting of Czech Urogynaecological Society, Prague, 2022 Y1 - 2022 ER - TY - GEN A1 - Melzner, Maximilian A1 - Engelhardt, Leonard A1 - Süß, Friedrich A1 - Dendorfer, Sebastian T1 - Sensitivity evaluation of a musculoskeletal hand model using Latin hypercube sampling T2 - ESMAC 2020 Abstracts Y1 - 2020 U6 - https://doi.org/10.1016/j.gaitpost.2020.08.008 VL - 81 IS - Suppl. 1 PB - Elsevier ER - TY - GEN A1 - Engelhardt, Lucas A1 - Melzner, Maximilian A1 - Havelkova, Linda A1 - Fiala, Pavel A1 - Rybarova, Martina A1 - Christen, Patrik A1 - Dendorfer, Sebastian A1 - Simon, Ulrich T1 - A new musculoskeletal AnyBody detailed hand model T2 - European Society of Biomechanics meeting 2019, Vienna, Austria N2 - The AnyBody™ Modeling System (AMS) [1], is an universally used musculoskeletal simulation software using inverse dynamics. Until now, no complete human hand model is known in the AMS. Also considering other musculoskeletal software platforms, just one detailed entire hand model is recently published [2] but is only based on one subject. The aim of this work is to implement a full detailed hand model for the AMS including all extrinsic and intrinsic muscles using data by the UWB gained through an anatomical study of ten cadaver hands. Y1 - 2019 UR - https://owncloud.tuwien.ac.at/index.php/s/dovqqcj02VeZHze ER - TY - GEN A1 - Auer, Simon A1 - Niebler, Michael A1 - Eiglsperger, Josef A1 - Kubowitsch, Simone A1 - Renkawitz, Tobias A1 - Achenbach, Leonard A1 - Krutsch, Werner A1 - Dendorfer, Sebastian T1 - Cognitive stress increases muscle forces in dynamic football specific movements T2 - European Society of Biomechanics meeting 2019, Vienna, Austria Y1 - 2019 UR - https://owncloud.tuwien.ac.at/index.php/s/dovqqcj02VeZHze ER - TY - GEN A1 - Aurbach, Maximilian A1 - Spicka, Jan A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Musculoskeletal modelling of the shoulder – effects on muscle recruitment and joint reaction force T2 - European Society of Biomechanics meeting 2019, Vienna, Austria Y1 - 2019 UR - https://owncloud.tuwien.ac.at/index.php/s/dovqqcj02VeZHze ER - TY - GEN A1 - Kubowitsch, Simone A1 - Süß, Franz A1 - Jansen, Petra A1 - Dendorfer, Sebastian T1 - Effect of dual tasking on muscular imbalances T2 - European Society of Biomechanics meeting 2019, Vienna, Austria Y1 - 2019 UR - https://owncloud.tuwien.ac.at/index.php/s/dovqqcj02VeZHze ER -