TY - GEN ED - Palm, Christoph ED - Breininger, Katharina ED - Deserno, Thomas M. ED - Handels, Heinz ED - Maier, Andreas ED - Maier-Hein, Klaus H. ED - Tolxdorff, Thomas M. T1 - Bildverarbeitung für die Medizin 2025 BT - Proceedings, German Conference on Medical Image Computing, Regensburg March 09-11, 2025 N2 - Die Konferenz "BVM - Bildverarbeitung für die Medizin" ist seit vielen Jahren als die nationale Plattform für den Austausch von Ideen und die Diskussion der neuesten Forschungsergebnisse im Bereich der Medizinischen Bildverarbeitung und der Künstlichen Intelligenz (KI) etabliert. Auch 2025 werden wir aktuelle Forschungsergebnisse vorstellen und Gespräche zwischen (jungen) Wissenschaftler*innen, Industrie und Anwender*innen vertiefen. Die Beiträge dieses Bandes – die meisten davon in englischer Sprache - umfassen alle Bereiche der medizinischen Bildverarbeitung, insbesondere die Bildgebung und -akquisition, Segmentierung und Analyse, Registrierung, Visualisierung und Animation, computerunterstützte Diagnose sowie bildgestützte Therapieplanung und Therapie. Hierbei kommen Methoden des maschinellen Lernens, der biomechanischen Modellierung sowie der Validierung und Qualitätssicherung zum Einsatz. Das Kapitel "Leveraging multiple total body segmentators and anatomy-informed post-processing for segmenting bones in Lung CTs" ist unter einer Creative Commons Attribution 4.0 International License über link.springer.com frei verfügbar (Open Access). Die Herausgebenden Prof. Palm forscht im Bereich KI für die Medizin mit einem Schwerpunkt in der Analyse endoskopischer Bilddaten zur computerunterstützten Diagnose und Therapie. Prof. Breininger entwickelt robuste Ansätze des maschinellen Lernens in verschiedenen interdisziplinären Bereichen, mit einem Schwerpunkt auf medizinischen Bilddaten. Prof. Deserno forscht in Biosignal- und Bilderzeugung und -verarbeitung, insbesondere in der videobasierten Vitaldatenmessung. Prof. Handels entwickelt problemoptimierte, lernfähige Bildverarbeitungsmethoden und integriert diese in hybride Bildverarbeitungssysteme zur Unterstützung der medizinischen Diagnostik und Therapie. Prof. Maier entwickelt Anwendungen in der medizinischen Bildverarbeitung zur Diagnoseunterstützung bis hin zur Schichtbildberechnung durch künstliche Intelligenz. Prof. Maier-Hein forscht im Bereich maschinelles Lernen und entwickelt Open-Source-Lösungen wie das Medical Imaging Interaction Toolkit (MITK), Kaapana oder das nnU-Net. Prof. em. Tolxdorff ist Experte für maschinelles Lernen, biomedizinisches Datenmanagement, Datenvisualisierung und -analyse sowie Medizinproduktentwicklung in klinischen Workflows. KW - Bildverarbeitung KW - Computerunterstützte Medizin KW - Bildgebendes Verfahren KW - Bildanalyse KW - Deep Learning Y1 - 2025 SN - 978-3-658-47421-8 U6 - https://doi.org/10.1007/978-3-658-47422-5 SN - 1431-472X PB - Springer Fachmedien Wiesbaden CY - Wiesbaden ER - TY - JOUR A1 - Hartwig, Regine A1 - Berlet, Maximilian A1 - Czempiel, Tobias A1 - Fuchtmann, Jonas A1 - Rückert, Tobias A1 - Feussner, Hubertus A1 - Wilhelm, Dirk T1 - Bildbasierte Unterstützungsmethoden für die zukünftige Anwendung in der Chirurgie JF - Die Chirurgie N2 - Hintergrund: Die Entwicklung assistiver Technologien wird in den kommenden Jahren nicht nur in der Chirurgie von zunehmender Bedeutung sein. Die Wahrnehmung der Istsituation stellt hierbei die Grundlage jeder autonomen Handlung dar. Hierfür können unterschiedliche Sensorsysteme genutzt werden, wobei videobasierte Systeme ein besonderes Potenzial aufweisen. Methode: Anhand von Literaturangaben und auf Basis eigener Forschungsarbeiten werden zentrale Aspekte bildbasierter Unterstützungssysteme für die Chirurgie dargestellt. Hierbei wird deren Potenzial, aber auch die Limitationen der Methoden erläutert. Ergebnisse: Eine etablierte Anwendung stellt die Phasendetektion chirurgischer Eingriffe dar, für die Operationsvideos mittels neuronaler Netzwerke analysiert werden. Durch eine zeitlich gestützte und transformative Analyse konnten die Ergebnisse der Prädiktion jüngst deutlich verbessert werden. Aber auch robotische Kameraführungssysteme nutzen Bilddaten, um das Laparoskop zukünftig autonom zu navigieren. Um die Zuverlässigkeit an die hohen Anforderungen in der Chirurgie anzugleichen, müssen diese jedoch durch zusätzliche Informationen ergänzt werden. Ein vergleichbarer multimodaler Ansatz wurde bereits für die Navigation und Lokalisation bei laparoskopischen Eingriffen umgesetzt. Hierzu werden Videodaten mittels verschiedener Methoden analysiert und diese Ergebnisse mit anderen Sensormodalitäten fusioniert. Diskussion: Bildbasierte Unterstützungsmethoden sind bereits für diverse Aufgaben verfügbar und stellen einen wichtigen Aspekt für die Chirurgie der Zukunft dar. Um hier jedoch zuverlässig und für autonome Funktionen eingesetzt werden zu können, müssen sie zukünftig in multimodale Ansätze eingebettet werden, um die erforderliche Sicherheit bieten zu können. T2 - Image-based supportive measures for future application in surgery KW - Künstliche Intelligenz KW - Robotik KW - Kognitiver Operationsaal KW - Autonomie KW - Digitalisierung Y1 - 2022 U6 - https://doi.org/10.1007/s00104-022-01668-x VL - 93 SP - 956 EP - 965 PB - Springer ER - TY - CHAP A1 - Rückert, Tobias A1 - Rieder, Maximilian A1 - Feussner, Hubertus A1 - Wilhelm, Dirk A1 - Rückert, Daniel A1 - Palm, Christoph ED - Maier, Andreas ED - Deserno, Thomas M. ED - Handels, Heinz ED - Maier-Hein, Klaus H. ED - Palm, Christoph ED - Tolxdorff, Thomas T1 - Smoke Classification in Laparoscopic Cholecystectomy Videos Incorporating Spatio-temporal Information T2 - Bildverarbeitung für die Medizin 2024: Proceedings, German Workshop on Medical Image Computing, March 10-12, 2024, Erlangen N2 - Heavy smoke development represents an important challenge for operating physicians during laparoscopic procedures and can potentially affect the success of an intervention due to reduced visibility and orientation. Reliable and accurate recognition of smoke is therefore a prerequisite for the use of downstream systems such as automated smoke evacuation systems. Current approaches distinguish between non-smoked and smoked frames but often ignore the temporal context inherent in endoscopic video data. In this work, we therefore present a method that utilizes the pixel-wise displacement from randomly sampled images to the preceding frames determined using the optical flow algorithm by providing the transformed magnitude of the displacement as an additional input to the network. Further, we incorporate the temporal context at evaluation time by applying an exponential moving average on the estimated class probabilities of the model output to obtain more stable and robust results over time. We evaluate our method on two convolutional-based and one state-of-the-art transformer architecture and show improvements in the classification results over a baseline approach, regardless of the network used. Y1 - 2024 U6 - https://doi.org/10.1007/978-3-658-44037-4_78 SP - 298 EP - 303 PB - Springeer CY - Wiesbaden ER - TY - INPR A1 - Mendel, Robert A1 - Rückert, Tobias A1 - Wilhelm, Dirk A1 - Rückert, Daniel A1 - Palm, Christoph T1 - Motion-Corrected Moving Average: Including Post-Hoc Temporal Information for Improved Video Segmentation N2 - Real-time computational speed and a high degree of precision are requirements for computer-assisted interventions. Applying a segmentation network to a medical video processing task can introduce significant inter-frame prediction noise. Existing approaches can reduce inconsistencies by including temporal information but often impose requirements on the architecture or dataset. This paper proposes a method to include temporal information in any segmentation model and, thus, a technique to improve video segmentation performance without alterations during training or additional labeling. With Motion-Corrected Moving Average, we refine the exponential moving average between the current and previous predictions. Using optical flow to estimate the movement between consecutive frames, we can shift the prior term in the moving-average calculation to align with the geometry of the current frame. The optical flow calculation does not require the output of the model and can therefore be performed in parallel, leading to no significant runtime penalty for our approach. We evaluate our approach on two publicly available segmentation datasets and two proprietary endoscopic datasets and show improvements over a baseline approach. KW - Deep Learning KW - Video KW - Segmentation Y1 - 2024 U6 - https://doi.org/10.48550/arXiv.2403.03120 ER - TY - GEN A1 - Scheppach, Markus W. A1 - Mendel, Robert A1 - Probst, Andreas A1 - Meinikheim, Michael A1 - Palm, Christoph A1 - Messmann, Helmut A1 - Ebigbo, Alanna T1 - Artificial Intelligence (AI) – assisted vessel and tissue recognition during third space endoscopy (Smart ESD) T2 - Zeitschrift für Gastroenterologie N2 - Clinical setting  Third space procedures such as endoscopic submucosal dissection (ESD) and peroral endoscopic myotomy (POEM) are complex minimally invasive techniques with an elevated risk for operator-dependent adverse events such as bleeding and perforation. This risk arises from accidental dissection into the muscle layer or through submucosal blood vessels as the submucosal cutting plane within the expanding resection site is not always apparent. Deep learning algorithms have shown considerable potential for the detection and characterization of gastrointestinal lesions. So-called AI – clinical decision support solutions (AI-CDSS) are commercially available for polyp detection during colonoscopy. Until now, these computer programs have concentrated on diagnostics whereas an AI-CDSS for interventional endoscopy has not yet been introduced. We aimed to develop an AI-CDSS („Smart ESD“) for real-time intra-procedural detection and delineation of blood vessels, tissue structures and endoscopic instruments during third-space endoscopic procedures. Characteristics of Smart ESD  An AI-CDSS was invented that delineates blood vessels, tissue structures and endoscopic instruments during third-space endoscopy in real-time. The output can be displayed by an overlay over the endoscopic image with different modes of visualization, such as a color-coded semitransparent area overlay, or border tracing (demonstration video). Hereby the optimal layer for dissection can be visualized, which is close above or directly at the muscle layer, depending on the applied technique (ESD or POEM). Furthermore, relevant blood vessels (thickness> 1mm) are delineated. Spatial proximity between the electrosurgical knife and a blood vessel triggers a warning signal. By this guidance system, inadvertent dissection through blood vessels could be averted. Technical specifications  A DeepLabv3+ neural network architecture with KSAC and a 101-layer ResNeSt backbone was used for the development of Smart ESD. It was trained and validated with 2565 annotated still images from 27 full length third-space endoscopic videos. The annotation classes were blood vessel, submucosal layer, muscle layer, electrosurgical knife and endoscopic instrument shaft. A test on a separate data set yielded an intersection over union (IoU) of 68%, a Dice Score of 80% and a pixel accuracy of 87%, demonstrating a high overlap between expert and AI segmentation. Further experiments on standardized video clips showed a mean vessel detection rate (VDR) of 85% with values of 92%, 70% and 95% for POEM, rectal ESD and esophageal ESD respectively. False positive measurements occurred 0.75 times per minute. 7 out of 9 vessels which caused intraprocedural bleeding were caught by the algorithm, as well as both vessels which required hemostasis via hemostatic forceps. Future perspectives  Smart ESD performed well for vessel and tissue detection and delineation on still images, as well as on video clips. During a live demonstration in the endoscopy suite, clinical applicability of the innovation was examined. The lag time for processing of the live endoscopic image was too short to be visually detectable for the interventionist. Even though the algorithm could not be applied during actual dissection by the interventionist, Smart ESD appeared readily deployable during visual assessment by ESD experts. Therefore, we plan to conduct a clinical trial in order to obtain CE-certification of the algorithm. This new technology may improve procedural safety and speed, as well as training of modern minimally invasive endoscopic resection techniques. KW - Artificial Intelligence KW - Medical Image Computing KW - Endoscopy KW - Bildgebendes Verfahren KW - Medizin KW - Künstliche Intelligenz KW - Endoskopie Y1 - 2022 U6 - https://doi.org/10.1055/s-0042-1755110 VL - 60 IS - 08 PB - Georg Thieme Verlag CY - Stuttgart ER - TY - GEN A1 - Meinikheim, Michael A1 - Mendel, Robert A1 - Probst, Andreas A1 - Scheppach, Markus W. A1 - Messmann, Helmut A1 - Palm, Christoph A1 - Ebigbo, Alanna T1 - Barrett-Ampel T2 - Zeitschrift für Gastroenterologie N2 - Hintergrund  Adenokarzinome des Ösophagus sind bis heute mit einer infausten Prognose vergesellschaftet (1). Obwohl Endoskopiker mit Barrett-Ösophagus als Präkanzerose konfrontiert werden, ist vor allem für nicht-Experten die Differenzierung zwischen Barrett-Ösophagus ohne Dysplasie und assoziierten Neoplasien mitunter schwierig. Existierende Biopsieprotokolle (z.B. Seattle Protokoll) sind oftmals unzuverlässig (2). Eine frühzeitige Diagnose des Adenokarzinoms ist allerdings von fundamentaler Bedeutung für die Prognose des Patienten. Forschungsansatz  Auf der Grundlage dieser Problematik, entwickelten wir in Kooperation mit dem Forschungslabor „Regensburg Medical Image Computing (ReMIC)“ der OTH Regensburg ein auf künstlicher Intelligenz (KI) basiertes Entscheidungsunterstützungssystem (CDSS). Das auf einer DeepLabv3+ neuronalen Netzwerkarchitektur basierende CDSS differenziert mittels Mustererkennung Barrett- Ösophagus ohne Dysplasie von Barrett-Ösophagus mit Dysplasie bzw. Neoplasie („Klassifizierung“). Hierbei werden gemittelte Ausgabewahrscheinlichkeiten mit einem vom Benutzer definierten Schwellenwert verglichen. Für Vorhersagen, die den Schwellenwert überschreiten, berechnen wir die Kontur der Region und die Fläche. Sobald die vorhergesagte Läsion eine bestimmte Größe in der Eingabe überschreitet, heben wir sie und ihren Umriss hervor. So ermöglicht eine farbkodierte Visualisierung eine Abgrenzung zwischen Dysplasie bzw. Neoplasie und normalem Barrett-Epithel („Segmentierung“). In einer Studie an Bildern in „Weißlicht“ (WL) und „Narrow Band Imaging“ (NBI) demonstrierten wir eine Sensitivität von mehr als 90% und eine Spezifität von mehr als 80% (3). In einem nächsten Schritt, differenzierte unser KI-Algorithmus Barrett- Metaplasien von assoziierten Neoplasien anhand von zufällig abgegriffenen Bildern in Echtzeit mit einer Accuracy von 89.9% (4). Darauf folgend, entwickelten wir unser System dahingehend weiter, dass unser Algorithmus nun auch dazu in der Lage ist, Untersuchungsvideos in WL, NBI und „Texture and Color Enhancement Imaging“ (TXI) in Echtzeit zu analysieren (5). Aktuell führen wir eine Studie in einem randomisiert-kontrollierten Ansatz an unveränderten Untersuchungsvideos in WL, NBI und TXI durch. Ausblick  Um Patienten mit aus Barrett-Metaplasien resultierenden Neoplasien frühestmöglich an „High-Volume“-Zentren überweisen zu können, soll unser KI-Algorithmus zukünftig vor allem Endoskopiker ohne extensive Erfahrung bei der Beurteilung von Barrett- Ösophagus in der Krebsfrüherkennung unterstützen. KW - Barrett-Ösophagus KW - Adenokarzinom KW - Künstliche Intelligenz KW - Speiseröhrenkrebs KW - Diagnose KW - Künstliche Intelligenz Y1 - 2022 U6 - https://doi.org/10.1055/s-0042-1755109 VL - 60 IS - 08 PB - Georg Thieme Verlag CY - Stuttgart ER - TY - GEN A1 - Scheppach, Markus W. A1 - Mendel, Robert A1 - Probst, Andreas A1 - Meinikheim, Michael A1 - Palm, Christoph A1 - Messmann, Helmut A1 - Ebigbo, Alanna T1 - Intraprozedurale Strukturerkennung bei Third-Space Endoskopie mithilfe eines Deep-Learning Algorithmus T2 - Zeitschrift für Gastroenterologie N2 - Einleitung Third-Space Interventionen wie die endoskopische Submukosadissektion (ESD) und die perorale endoskopische Myotomie (POEM) sind technisch anspruchsvoll und mit einem erhöhten Risiko für intraprozedurale Komplikationen wie Blutung oder Perforation assoziiert. Moderne Computerprogramme zur Unterstützung bei diagnostischen Entscheidungen werden unter Einsatz von künstlicher Intelligenz (KI) in der Endoskopie bereits erfolgreich eingesetzt. Ziel der vorliegenden Arbeit war es, relevante anatomische Strukturen mithilfe eines Deep-Learning Algorithmus zu detektieren und segmentieren, um die Sicherheit und Anwendbarkeit von ESD und POEM zu erhöhen. Methoden Zwölf Videoaufnahmen in voller Länge von Third-Space Endoskopien wurden aus der Datenbank des Universitätsklinikums Augsburg extrahiert. 1686 Einzelbilder wurden für die Kategorien Submukosa, Blutgefäß, Dissektionsmesser und endoskopisches Instrument annotiert und segmentiert. Mit diesem Datensatz wurde ein DeepLabv3+neuronales Netzwerk auf der Basis eines ResNet mit 101 Schichten trainiert und intern anhand der Parameter Intersection over Union (IoU), Dice Score und Pixel Accuracy validiert. Die Fähigkeit des Algorithmus zur Gefäßdetektion wurde anhand von 24 Videoclips mit einer Spieldauer von 7 bis 46 Sekunden mit 33 vordefinierten Gefäßen evaluiert. Anhand dieses Tests wurde auch die Gefäßdetektionsrate eines Experten in der Third-Space Endoskopie ermittelt. Ergebnisse Der Algorithmus zeigte eine Gefäßdetektionsrate von 93,94% mit einer mittleren Rate an falsch positiven Signalen von 1,87 pro Minute. Die Gefäßdetektionsrate des Experten lag bei 90,1% ohne falsch positive Ergebnisse. In der internen Validierung an Einzelbildern wurde eine IoU von 63,47%, ein mittlerer Dice Score von 76,18% und eine Pixel Accuracy von 86,61% ermittelt. Zusammenfassung Dies ist der erste KI-Algorithmus, der für den Einsatz in der therapeutischen Endoskopie entwickelt wurde. Präliminäre Ergebnisse deuten auf eine mit Experten vergleichbare Detektion von Gefäßen während der Untersuchung hin. Weitere Untersuchungen sind nötig, um die Leistung des Algorithmus im Vergleich zum Experten genauer zu eruieren sowie einen möglichen klinischen Nutzen zu ermitteln. KW - Deep Learning KW - Third-Space Endoscopy Y1 - 2022 U6 - https://doi.org/10.1055/s-0042-1745652 VL - 60 IS - 04 PB - Thieme CY - Stuttgart ER - TY - JOUR A1 - Souza Jr., Luis Antonio de A1 - Pacheco, André G.C. A1 - Passos, Leandro A. A1 - Santana, Marcos Cleison S. A1 - Mendel, Robert A1 - Ebigbo, Alanna A1 - Probst, Andreas A1 - Messmann, Helmut A1 - Palm, Christoph A1 - Papa, João Paulo T1 - DeepCraftFuse: visual and deeply-learnable features work better together for esophageal cancer detection in patients with Barrett’s esophagus JF - Neural Computing and Applications N2 - Limitations in computer-assisted diagnosis include lack of labeled data and inability to model the relation between what experts see and what computers learn. Even though artificial intelligence and machine learning have demonstrated remarkable performances in medical image computing, their accountability and transparency level must be improved to transfer this success into clinical practice. The reliability of machine learning decisions must be explained and interpreted, especially for supporting the medical diagnosis. While deep learning techniques are broad so that unseen information might help learn patterns of interest, human insights to describe objects of interest help in decision-making. This paper proposes a novel approach, DeepCraftFuse, to address the challenge of combining information provided by deep networks with visual-based features to significantly enhance the correct identification of cancerous tissues in patients affected with Barrett’s esophagus (BE). We demonstrate that DeepCraftFuse outperforms state-of-the-art techniques on private and public datasets, reaching results of around 95% when distinguishing patients affected by BE that is either positive or negative to esophageal cancer. KW - Deep Learning KW - Speiseröhrenkrebs KW - Adenocarcinom KW - Endobrachyösophagus KW - Diagnose KW - Maschinelles Lernen KW - Machine learning KW - Adenocarcinoma KW - Object detector KW - Barrett’s esophagus KW - Deep Learning Y1 - 2024 U6 - https://doi.org/10.1007/s00521-024-09615-z VL - 36 SP - 10445 EP - 10459 PB - Springer CY - London ER - TY - JOUR A1 - Souza, Luis A. A1 - Pacheco, André G.C. A1 - de Souza, Alberto F. A1 - Oliveira-Santos, Thiago A1 - Badue, Claudine A1 - Palm, Christoph A1 - Papa, João Paulo T1 - TransConv: a lightweight architecture based on transformers and convolutional neural networks for adenocarcinoma and Barrett’s esophagus identification JF - Neural Computing and Applications N2 - Barrett’s esophagus, also known as BE, is commonly associated with repeated exposure to stomach acid. If not treated properly, it may evolve into esophageal adenocarcinoma, aka esophageal cancer. This paper proposes TransConv, a hybrid architecture that benefits from features learned by pre-trained vision transformers (ViTs) and convolutional neural networks (CNNs), followed by a shallow neural network composed of three normalizations, ReLU activations, and fully connected layers, and a SoftMax head to distinguish between BE and esophageal cancer. TransConv is designed to be training-lightweight, and for the ViT and CNN backbone models, weights are kept frozen during training, i.e., the primary goal of TransConv is to learn the weights of the fully connected layer from both backbones only, avoiding the burden of updating their weights but still learning their final descriptions for the lightweight convolutional model. We report promising results with low computational training costs in two datasets, one public and another private. From our achievements, TransConv was able to deliver balanced accuracy results around 85% and 86% for each evaluated dataset, respectively, in a design that required only 50 epochs of model training, a very reduced number compared to state-of-the-art conducted studies in the same domain. Y1 - 2025 U6 - https://doi.org/10.1007/s00521-025-11299-y IS - 37 SP - 15535 EP - 15546 PB - Springer ER - TY - INPR A1 - Rückert, Tobias A1 - Rückert, Daniel A1 - Palm, Christoph T1 - Methods and datasets for segmentation of minimally invasive surgical instruments in endoscopic images and videos: A review of the state of the art N2 - In the field of computer- and robot-assisted minimally invasive surgery, enormous progress has been made in recent years based on the recognition of surgical instruments in endoscopic images. Especially the determination of the position and type of the instruments is of great interest here. Current work involves both spatial and temporal information with the idea, that the prediction of movement of surgical tools over time may improve the quality of final segmentations. The provision of publicly available datasets has recently encouraged the development of new methods, mainly based on deep learning. In this review, we identify datasets used for method development and evaluation, as well as quantify their frequency of use in the literature. We further present an overview of the current state of research regarding the segmentation and tracking of minimally invasive surgical instruments in endoscopic images. The paper focuses on methods that work purely visually without attached markers of any kind on the instruments, taking into account both single-frame segmentation approaches as well as those involving temporal information. A discussion of the reviewed literature is provided, highlighting existing shortcomings and emphasizing available potential for future developments. The publications considered were identified through the platforms Google Scholar, Web of Science, and PubMed. The search terms used were "instrument segmentation", "instrument tracking", "surgical tool segmentation", and "surgical tool tracking" and result in 408 articles published between 2015 and 2022 from which 109 were included using systematic selection criteria. Y1 - 2023 U6 - https://doi.org/10.48550/arXiv.2304.13014 ER - TY - JOUR A1 - Safi, Hila A1 - Bandic, Medina A1 - Niedermeier, Christoph A1 - Almudever, Carmen G. A1 - Feld, Sebastian A1 - Mauerer, Wolfgang T1 - Stacking the odds: full-stack quantum system design space exploration JF - EPJ Quantum Technology N2 - Design space exploration (DSE) plays an important role in optimising quantum circuit execution by systematically evaluating different configurations of compilation strategies and hardware settings. In this paper, we conduct a comprehensive investigation into the impact of various layout methods, qubit routing techniques, and optimisation levels, as well as device-specific properties such as different variants and strengths of noise and imperfections, the topological structure of qubits, connectivity densities, and back-end sizes. By spanning through these dimensions, we aim to understand the interplay between compilation choices and hardware characteristics. A key question driving our exploration is whether the optimal selection of device parameters, mapping techniques, comprising of initial layout strategies and routing heuristics can mitigate device induced errors beyond standard error mitigation approaches. Our results show that carefully selecting software strategies (e.g., mapping and routing algorithms) and tailoring hardware characteristics (such as minimising noise and leveraging topology and connectivity density) significantly improve the fidelity of circuit execution outcomes, and thus the expected correctness or success probability of the computational result. We provide estimates based on key metrics such as circuit depth, gate count and expected fidelity. Our results highlight the importance of hardware–software co-design, particularly as quantum systems scale to larger dimensions, and along the way towards fully error corrected quantum systems: Our study is based on computationally noisy simulations, but considers various implementations of quantum error correction (QEC) using the same approach as for other algorithms. The observed sensitivity of circuit fidelity to noise and connectivity suggests that co-design principles will be equally critical when integrating QEC in future systems. Our exploration provides practical guidelines for co-optimising physical mapping, qubit routing, and hardware configurations in realistic quantum computing scenarios. Y1 - 2025 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-85157 N1 - Corresponding author der OTH Regensburg: Hila Safi VL - 12 PB - Springer CY - Heidelberg ER - TY - CHAP A1 - Graf, Julian A1 - Hachani, Murad A1 - Fischer, Sebastian A1 - Hackenberg, Rudolf T1 - A heuristic packet processing model for improved encrypted network analysis T2 - CSCS '25: Proceedings of the 2nd Cyber Security in CarS Workshop N2 - Modern networked systems, such as those in the automotive sector, face increasing complexity and growing attack surfaces due to the rise of interconnected and data-driven technologies. Detecting malicious behavior in these environments requires efficient and scalable methods that can operate reliably despite limited resources and high communication volumes. This paper proposes a heuristic packet processing model designed to support intrusion detection based on structural and temporal characteristics of encrypted network traffic. The model follows a modular architecture consisting of four key phases: recording, sorting, prioritizing, and analyzing. At the core of the approach is the Polymetric Queueing Topology Space, a feature space that combines statistical and time series attributes derived from model structure and flow data. These features serve as input for machine learning models, which can effectively distinguish between benign and intrusion traffic patterns without relying on packet data beyond the transport layer. The approach was evaluated using the publicly available ToN_IoT dataset and demonstrated that reliable classification is achievable using a subset of the developed feature space that contains model-derived traffic features. We used Random Forest for supervised binary and multi-class classification achieving high accuracy scores of 99% for binary and 98% for multi-class classification. Additionally, for unsupervised anomaly detection, we created an Isolation Forest model accomplishing F1-scores of 0.92 for the benign and 0.96 for intrusion class. The architecture is designed to enable dynamic traffic prioritization and to offer a flexible foundation that can observe diverse network domains while maintaining efficient performance under constrained computational conditions. Y1 - 2025 U6 - https://doi.org/10.1145/3736130.3764510 PB - ACM CY - New York, USA ER - TY - GEN A1 - Hauser, Dominic A1 - Graf, Julian A1 - Fischer, Sebastian T1 - SEPP – Security Education and Penetration-Testing Platform for IoT T2 - Conference programme & abstract book N2 - The Internet of Things (IoT) is becoming a major part of our everyday lives, offering convenience and smarter solutions, but also bringing significant security challenges. While theoretical knowledge in IoT security is essential, studies have shown that practical content can be an essential part of internalizing understanding. To address this, we developed the Security Education and Penetration-Testing Platform (SEPP) as the practical component of an existing IoT security course at the OTH Regensburg. SEPP uses real IoT devices like smart locks, cameras, and plugs, simulating a smart home environment to make learning interactive and engaging. Students can explore vulnerabilities, conduct penetration tests, and document their findings through structured exercises. By working on tasks like network scanning, analyzing data traffic, and simulating attacks, students gain a deeper understanding of IoT security risks. Initial tests show that this approach helps students apply their theoretical knowledge and significantly improve their practical skills. This paper explains how SEPP was built, the exercises it offers, and why it’s an important step forward in teaching IoT security effectively. Furthermore, we aim to share the findings and tasks from this paper with other universities, providing them with a solid foundation to teach practical IoT security knowledge in their own courses. Y1 - 2025 UR - https://iafor.org/archives/conference-programmes/ece/ece-programme-2025.pdf SN - 2433-7544 SP - 101 PB - IAFOR ER - TY - GEN A1 - Fischer, Sebastian T1 - The persistent problems with cybersecurity : a negative example and an outlook on the Cyber Resilience Act Y1 - 2025 UR - https://www.iaria.org/conferences2025/filesDataSys25/Keynote_SebastianFischer_ThePersistentProblem.pdf PB - IARIA ER - TY - CHAP A1 - Bauer, Patrick A1 - Frikel, Jürgen T1 - BPConvNet: a deep learning based ρ-Filtered layergram reconstruction method for computed tomography T2 - AIP Conference Proceedings N2 - In this article, we address the reconstruction problem in computed tomography (CT) when dealing with sparse view data. Traditional approaches like filtered backprojection (FBP) often fail under these conditions, leading to streaking artifacts. We propose BPConvNet, a deep learning based version of the ρ-filtered layergram or backprojection filtration (BPF) technique (cf. [1]). Unlike FBP, the BPF method applies filtering (F) after backprojection (BP), hence the name. The proposed BPConvNet adapts the BPF workflow by substituting the filtering step with a residual convolutional neural network. Our numerical experiments demonstrate that BPConvNet is competitive to similar deep learning methods. Moreover, we explain that BPConvNet can be easily adapted to to different CT acquisition geometries, such as fan beam and 3D configurations KW - Convolutional neural network KW - Deep learning KW - Learning and learning models KW - Computed tomography Y1 - 2025 U6 - https://doi.org/10.1063/5.0286063 SN - 0094-243X VL - 3315 IS - 1 PB - AIP Publishing ER - TY - THES A1 - Schaffer, Josefa T1 - Precision in eye tracking: evaluation and improvement of accuracy N2 - This thesis will evaluate the accuracy of the Tobii Pro Glasses 3, which are wearable eye tracking glasses. A static and dynamic accuracy study will be conducted, utilising a poster and imitating realistic environments. The results will be evaluated using a self-developed sample-wise approach, trying to determine possible differences between static and dynamic conditions while wearing eye tracking glasses. In addition to that, a tool named glassesValidator, used to calculate data quality metrics of eye tracking glasses, will be evaluated on its accuracy and validity itself. In the static accuracy study, participants will focus, in reading order, on nine fixation targets on the poster for at least two seconds while using a chin rest to prevent head movement. In the dynamic accuracy study participants will be walking in a semicircular movement around the poster while focusing only on the central fixation target on the poster. The results for the static and dynamic study will be compared to each other, providing possible influence of different lighting conditions and the usage of contact lenses. The results provided by glassesValidator and the self-developed accuracy approach will also be compared to each other to evaluate and provide possible improvements to increase the accuracy of the tool. Y1 - 2025 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-85296 CY - Regensburg ER - TY - JOUR A1 - Neubauer, Katrin A1 - Fischer, Sebastian A1 - Hackenberg, Rudolf T1 - Security risk analysis of the cloud infrastructure of Smart Grid and IoT - 4-Level-Trust-Model as a security solution JF - International Journal on Advances in Internet Technology N2 - The digital transformation has found its way into business and private life. It consists of digitization and digitaliza- tion. Digitization means the technical process and digitalization is the socio-technological process. Technologies of digitization are Cloud Computing (CC), Internet of Things (IoT) and Smart Grid (SG), which are separate technologies. The increasing digitalization in the private sector and of the energy industry connect these technologies. Actually, there is no connection between the CC infrastructure and the SG infrastructure at the moment, because in Germany the SG is currently under construction. If one looks at the CC and IoT, it must be stated there is an connection between the IoT infrastructure and the CC infrastructure as a service provider. To connect the technologies CC, IoT and SG and also build an SG cloud for innovative services, the new laws for privacy must be implemented. For privacy and security analyses it is important to know which data can be stored and distributed on a cloud. To illustrate this analysis, we connect the SG infrastructure with the IoT. An IoT device (car charging station) should be able to transfer data to and from the SG. SG is a critical infrastructure and the IoT device a potential insecure device and network. We show the communication between the smart meter switching box and the IoT device and the data transferred between their clouds. The charging station is connected to the SG to get the current amount of renewable energy in the grid. This is necessary to create a new smart service. But this service also generates private data (e.g., name, address, payment details). The private data should not be transferred to the IoT cloud. For the connection of SG and IoT, availability, confidentiality and integrity must be ensured. A risk analysis over all the cloud connections, including the vulnerability and the ability of an attacker, the resulting risk and the 4-Level- Trust-Model for security assessment are developed. Furthermore, we show the application of the 4-Level-Trust-Model in this paper. Y1 - 2020 UR - https://www.researchgate.net/publication/346580224_Security_Risk_Analysis_of_the_Cloud_Infrastructure_of_Smart_Grid_and_IoT_-_4-Level-Trust-Model_as_a_Security_Solution UR - https://www.iariajournals.org/internet_technology/inttech_v13_n12_2020_paged.pdf VL - 13 IS - 1&2 SP - 11 EP - 20 ER - TY - CHAP A1 - Schwägerl, Felix A1 - Buchmann, Thomas A1 - Westfechtel, Bernhard T1 - Multi-variant model transformations - a problem statement T2 - Proceedings of the 11th International Conference on Evaluation of Novel Software Approaches to Software Engineering N2 - Model Transformations are a key element of Model-Driven Software Engineering. As soon as variability is involved, transformations become increasingly complicated. The lack of support for variability in model transformations impairs the acceptance of approaches to organized reuse such as software product lines. In this position paper, the general problem of multi-variant model transformations is formulated for MOF-based, XMI-serialized models. A simplistic case study is presented to specify the input and the expected output of such a transformation. Furthermore, requirements for tool support are defined, including a standardized representation of both multi-variant model instances and variability information, as well as an execution specification for multi-variant transformations. A literature review reveals that the problem is weakly identified and often solved using ad-hoc solutions; there exists no tool providing a general solution to the proposed problem statement. The observation s presented here may serve for the future development of standards and tools. KW - Model-Driven Software Engineering KW - Software Product Lines KW - Model Transformations KW - Code Generation Y1 - 2016 SN - 978-989-758-189-2 U6 - https://doi.org/10.5220/0005878702030209 SN - 2184-4895 SP - 203 EP - 209 PB - SCITEPRESS ER - TY - RPRT A1 - Alex, Karla A1 - Eichinger, Johanna A1 - Heyder, Clemens A1 - Kandlbinder, Agnes A1 - Loder, Sandra A1 - Rolfes, Vasilija A1 - Röttger, Sara A1 - Scharf, Anna A1 - Scorna, Ulrike A1 - Weigold, Stefanie ED - Cerullo, Laura ED - Gerhards, Helene ED - Weber, Karsten T1 - Abstractband I: In-vitro-Gametogenese (IVG) und artifizieller Uterus (AU) – Problemauslöser oder Problemlöser? Ethische, soziale und rechtliche Aspekte zukünftiger reproduktionsmedizinischer Verfahren BT - Klausurwoche für Early Career Researchers (19. September bis 23. September 2022, OTH Regensburg) Y1 - 2022 U6 - https://doi.org/10.13140/RG.2.2.30303.53928 N1 - Die Klausurwoche wird vom Bundesministerium für Bildung und Forschung (BMBF) (Förderkennzeichen: 01GP2185, Projektkürzel: IVG-AU-PP) finanziell gefördert. ER - TY - JOUR A1 - Hantsch, Carolin A1 - Westner, Markus A1 - Matschi, Markus T1 - IT/OT-Konvergenz: Status-Quo und Umsetzungsempfehlungen JF - HMD Praxis der Wirtschaftsinformatik N2 - Organisationen machen große Anstrengungen zur Verbesserung ihrer Ambidextrie, d. h. ihrer Fähigkeit sowohl Exploitationsziele (z. B. Effizienz, Vorhersagbarkeit) als auch Explorationsziele (z. B. Anpassbarkeit, Innovation) zu erreichen. Obwohl gemäß der Praxisliteratur Technologie in Software-Projekten dabei eine zentrale Rolle spielen kann, gibt es kaum Forschung dazu, wie technologische Faktoren Ambidexterie in Software-Projekten beeinflussen. In dieser Studie untersuchen wir die Rolle dreier technologischer Faktoren: kontinuierliche Integration, Standardisierung und Microservice-Architektur. Die Ergebnisse einer Mehrinformanten-Umfrage in 95 Projekten in der Schweiz und Dänemark zeigen, dass kontinuierliche Integration und Standardisierung mit höherer Ambidexterie einhergehen, während der Zusammenhang zwischen Microservice-Architektur und Ambidextrie nicht signifikant ist. Unser Artikel geht über die existierende Forschung hinaus, indem er zeigt, dass kontinuierliche Integration und Standardisierung nicht nur Exploitation, sondern auch Exploration fördern können. Wir diskutieren auch Gründe für den insignifikanten Zusammenhang zwischen Microservice-Architektur und Ambidextrie. N2 - This study examines IT/OT Convergence in 31 predominantly large German companies. It presents an “IT/OT Governance Framework” as a specific model for successful convergence implementation. The analysis reveals a heterogeneous level of convergence maturity across the examined companies, the majority of which are at the beginning or in the implementation phase. Close cooperation between IT and OT is favored, but without IT completely taking over OT. An IT/OT tandem consisting of a CIO and a central OT responsible person is seen as the ideal way to take responsibility. Six specific recommendations were derived from the interviews and included in the IT/OT Governance Framework developed. These include ensuring top management support, using security as a driver, introducing a central OT responsible person, bringing IT and OT teams physically closer together, continuously demonstrating the added value of convergence, and taking a step-by-step approach to implementation. KW - IT/OT Convergence KW - Operational Technology KW - OT KW - Governance Y1 - 2024 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-77937 N1 - Corresponding author der OTH Regensburg: Markus Westner PB - Springer Nature ER - TY - JOUR A1 - Schultz, Maximilian A1 - Hauer, Franziska A1 - Haug, Sonja A1 - Weber, Karsten T1 - Künstliche Intelligenz in sozialen Organisationen implementieren BT - von der Einzelinitiative zur Strategie JF - Sozialwirtschaft N2 - Die Digitalisierung wird in der Gesellschaft seit vielen Jahren thematisiert. Durch Künstliche Intelligenz (KI) hat diese Diskussion einen zusätzlichen Anstoß bekommen. Inbesondere für gemeinwohlorientierte Organisationen bieten sich Potenziale sowie Risiken. Sie könnten zur Entlastung von Fachkräften, zur Verbesserung organisatorischer Abläufe und zur Entwicklung neuer Unterstützungsangebote beitragen. Angesichts chronischer Herausforderungen wie Fachkräftemangel, Ressourcenknappheit und wachsender Komplexität von Arbeitsprozessen erscheint KI daher als möglicher Hebel für eine tiefgreifende Transformation. KW - KI KW - Sozialwirtschaft Y1 - 2025 U6 - https://doi.org/10.5771/1613-0707-2025-5-35 VL - 35 IS - 5 SP - 35 EP - 38 PB - nomos Verlag ER - TY - GEN A1 - Weber, Karsten T1 - KI-Nutzung für (psychisch) kranke Menschen: Auswirkungen auf das Professionsverständnis der Fachkräfte Y1 - 2024 ER - TY - GEN A1 - Weber, Karsten T1 - Elektrisch + digital = nachhaltig? Welche Nachhaltigkeitsgewinne haben neue Mobilitätformen? Y1 - 2023 ER - TY - GEN A1 - Weber, Karsten T1 - Medizin, Mobilität, Medien: Digitaler Wandel als Chance und Herausforderung Y1 - 2023 ER - TY - GEN A1 - Weber, Karsten T1 - Der Mars zwischen Science und Fiction Y1 - 2023 ER - TY - GEN A1 - Weber, Karsten T1 - Nachhaltigkeit ist (k)eine Frage der Philosophie Y1 - 2025 ER - TY - GEN A1 - Weber, Karsten T1 - Mögliche Zukünfte der Künstlichen Intelligenz Y1 - 2023 ER - TY - GEN A1 - Weber, Karsten T1 - Mögliche Zukünfte der Künstlichen Intelligenz Y1 - 2023 ER - TY - GEN A1 - Weber, Karsten T1 - Der Mensch nach Maß?! Y1 - 2023 ER - TY - GEN A1 - Weber, Karsten T1 - The weapons of war and conflict are technology BT - Security from the viewpoint of Technology Assessment Y1 - 2023 ER - TY - GEN A1 - Weber, Karsten T1 - Social science research, research on acceptance, and applied ethics on technology and artificial intelligence in the health sector Y1 - 2024 ER - TY - GEN A1 - Weber, Karsten T1 - KI und Roboter in der Science Fiction – eine (augenzwinkernde) Einführung zur KI-Forschung Y1 - 2024 ER - TY - GEN A1 - Weber, Karsten T1 - Die üblichen Verdächtigen – automatisierte Strafverfolgung aus Perspektive der Technikfolgenabschätzung und Technikbewertung Y1 - 2024 ER - TY - GEN A1 - Weber, Karsten T1 - Nutzungsdauer und Recycling softwareabhängiger Geräte – Herausforderungen und mögliche Lösungsansätze Y1 - 2023 ER - TY - GEN A1 - Weber, Karsten T1 - Digitalisierung, KI, Robotik – Visionen für die Gesundheitsversorgung von morgen Y1 - 2024 ER - TY - GEN A1 - Weber, Karsten T1 - Verstand, Vernunft, Seele: Was unterscheidet KI-Systeme von Menschen? Y1 - 2024 ER - TY - GEN A1 - Weber, Karsten T1 - KI und Big Data: Wenn ein Hype zum ethischen Stolperstein wird Y1 - 2025 ER - TY - GEN A1 - Weber, Karsten T1 - Aspekte der sozialen Nachhaltigkeit am Beispiel des Einsatzes von KI. Ergebnisse einer Befragung von zivilgesellschaftlichen Organisationen in der Grenzregion im Bereich Umweltschutz, Sozial- und Gesundheitswesen T2 - Aspekty sociální udržitelnosti na příkladu využití umělé inteligence. Výsledky průzkumu mezi občanskými organizacemi v pohraniční oblasti v oblasti ochrany životního prostředí, sociálních věcí a zdravotnictví a lidských práv Y1 - 2025 ER - TY - GEN A1 - Weber, Karsten T1 - Künstliche Intelligenz für Nichtregierungsorganisationen (KINiro) – Bedarf, Akzeptanz und Umsetzungsmöglichkeiten Y1 - 2025 ER - TY - GEN A1 - Weber, Karsten T1 - Zwischen Fortschritt und Verantwortung: KI, Nachhaltigkeit und wir Y1 - 2025 ER - TY - GEN A1 - Weber, Karsten T1 - Künstliche Intelligenz: Ökonomische und ethische Aspekte Y1 - 2025 ER - TY - GEN A1 - Weber, Karsten T1 - KI ./. Demokratie BT - Ein kompliziertes Verhältnis Y1 - 2024 ER - TY - CHAP A1 - Vetter, Miriam A1 - Haug, Sonja A1 - Weber, Karsten ED - BBSR – Bundesinstitut für Bau-, Stadt- und Raumforschung im Bundesamt für Bauwesen und Raumordnung, T1 - Die Zukunft der Notfallerkennung in Haushalten älterer Menschen : eine Technikbewertung T2 - Demografische Alterungsprozesse : Chancen und Herausforderungen für die Regionalentwicklung N2 - Die meisten älteren Personen wünschen sich ein Altern in der Häuslichkeit, auch bei zunehmendem Anteil an Pflegebedürftigen in der Bevölkerung. Der Pflegenotstand im ländlichen Raum und im ambulanten Bereich stellt die häusliche Versorgung jedoch vor Herausforderungen. Die Digitalisierung soll dabei Abhilfe schaffen. Hausnotrufsysteme sind eine weit verbreitete Form digitaler Assistenzsysteme, die auf Knopfdruck Hilferufe an Hausnotrufzentralen übermitteln. Sie stehen jedoch in der Kritik, da die Handsender aus Angst vor Stigmatisierung von den Pflegebedürftigen oft abgelegt und daher trotz Notlage nicht genutzt werden. Neben vielfältiger Forschung zu digitalen Assistenzsystemen werden zunehmend technische Prototypen zu Smart-Meter-Anwendungen zur Notfallerkennung für ältere Menschen entwickelt, die mithilfe von Stromverbrauchsdaten und Künstlicher Intelligenz auf Inaktivität und somit mögliche Notfälle schließen. Smart-Meter sind intelligente Messsysteme, die für bestimmte Privathaushalte gesetzlich verpflichtend eingeführt werden, um Netzstabilität zu gewährleisten. Dieser Beitrag stellt erste Ergebnisse einer Technikbewertung mithilfe eines Mixed-Method-Ansatzes vor. Ein Drittel der Expertinnen und Experten sieht eine positive Nutzungsintention. Die Bevölkerungsbefragung zeigt Unentschlossenheit bezüglich der neuen Technologie. Eine Nutzungsintention besteht vor allem bei jüngeren technikaffinen Personen, d.h. den älteren Menschen der Zukunft. KW - Notfallerkennung KW - Smart Meter KW - Akzeptanz Y1 - 2025 U6 - https://doi.org/10.58007/gcpc-7j48 SN - 1868-0097 SP - 126 EP - 136 PB - BBSR – Bundesinstitut für Bau-, Stadt- und Raumforschung im Bundesamt für Bauwesen und Raumordnung (BBR) CY - Bonn ER - TY - JOUR A1 - Bedbur, Stefan A1 - Kamps, Udo A1 - Schmiedt, Anja Bettina T1 - A flexible model of ordered random variables for non-metallic inclusions in steels and related statistical inference JF - Applied Mathematical Modelling N2 - In a data set of non-metallic inclusion sizes in samples from engineering steel, common order statistics fail to serve as a suitable model for ascendingly ordered measurements within single samples. Therefore, a flexible model of ordered random variables is proposed, which allows for changes of distributions described by model parameters. Joint maximum likelihood estimation of these parameters and the shape parameter of an underlying left-truncated Weibull distribution is considered, and a model test is developed for the null-hypothesis of common order statistics being an adequate model. To overcome small data situations, a link-function approach is examined in order to reduce the number of involved model parameters as well as to propose to use a link-function parameter as a material indicator. An asymptotic test is provided to check for the presence of a linear link function, and tests for hypotheses about two link-function parameters are studied. Moreover, the construction of simultaneous confidence regions for the link-function parameters as well as of confidence bands for the entire graph of the link function are presented. Throughout, the findings are applied to the real metallurgical data set. Similar problems and data structures arise in other fields of material science and applications such as geology. Y1 - 2026 U6 - https://doi.org/10.1016/j.apm.2025.116284 SN - 0307-904X N1 - Corresponding author der OTH Regensburg: Anja Bettina Schmiedt VL - 149 PB - Elsevier ER - TY - JOUR A1 - Schmiedt, Anja B. A1 - Empacher, Christina A1 - Kamps, Udo T1 - One- and two-sided prediction intervals for future Pareto record values with applications JF - Journal of Statistical Theory and Applications N2 - Based on upper record values in a series of observations over time from a Pareto distribution, an exact and several approximate one-sided and two-sided prediction intervals for the next record value (or for another future record value) to appear are studied and compared by means of an extensive simulation study. The performances of the prediction intervals are evaluated and recommendations are proposed for what method should be used in a given situation with respect to the form of the prediction interval on the one hand and to the tail behaviour on the other. The proposed methods are applied to insurance, environmental and sports data, where the respectively fitted Pareto distributions show a different tail behaviour. As a result, it is seen that although the number of observed record values in the presented real data applications is rather small, as it is usually the case, the selected prediction intervals are of practical use. KW - Interval prediction KW - Pareto distribution KW - Real data analyses KW - Record values KW - Simulation study Y1 - 2025 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-81605 SN - 2214-1766 N1 - Corresponding author der OTH Regensburg: Anja B. Schmiedt PB - Springer ER - TY - JOUR A1 - Dotter, Caroline A1 - Haug, Sonja A1 - Schnell, Rainer A1 - Raptis, Georgios A1 - Weber, Karsten T1 - Sharing health data for research purposes: results of a population survey in Germany JF - BMC health services research N2 - BACKGROUND: Increased use of health data has the potential to improve both health care and health policies. Several recent policy initiatives at the European and German legislative levels aim to increase the primary and secondary use of health data. However, little is known about general population views on health data access for research. Most studies are based on subsets defined by specific illnesses. METHODS: We commissioned a national computer-assisted dual-frame telephone survey (landline and mobile). Logit estimation models were used to identify predictors of willingness to provide access to health data to different organizations (universities in Germany, universities worldwide, German government organizations, pharmaceutical companies). RESULTS: A high willingness to share health data for research purposes is observed, depending on the specific data recipient. The willingness is highest for research at universities in Germany and German governmental organizations, and lowest regarding research by pharmaceutical companies. The main drivers for sharing health data are the level of trust in public institutions, the respondents' assessment of the seriousness and likelihood of data misuse, and the level of digital literacy. Age, gender, and level of education have small effects and do not determine the willingness to share health data for all organizations. CONCLUSION: We present evidence from a random sample of the German population. The results indicate widespread support among the population for providing access to health data for research purposes. Similar to findings in other countries, the willingness depends strongly on the recipient of the data. This paper evaluates the impact of various determinants - identified in previous qualitative and quantitative research - on the willingness of the German population to share health data. While previous studies have found that patients are generally more willing to share health data, we found that the presence of a medical precondition does not translate into respondents' unequivocal support for health data sharing. We identify privacy concerns, general trust, and digital literacy as key factors influencing the willingness to share health data. Therefore, policymakers and stakeholders need to ensure and communicate the necessary privacy protection measures to increase the willingness of the German population to share health data. Y1 - 2025 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-81622 N1 - Corresponding author der OTH Regensburg: Caroline Dotter VL - 25 PB - BMC ER - TY - CHAP A1 - Schwägerl, Felix A1 - Uhrig, Sabrina T1 - Tool Support for the Evaluation of Matching Algorithms in the Eclipse Modeling Framework T2 - Proceedings of the 1st International Conference on Model-Driven Engineering and Software Development, February 19-21, 2013, in Barcelona, Spain, Vol. 1 N2 - In the field of model-driven development, sophisticated support for comparing model versions is urgently needed. Unfortunately, algorithms for model matching have been rarely evaluated so far. This paper deals with two extensions to the Eclipse Modeling Framework (EMF) that facilitate the evaluation of matching algorithms for EMF models, with the goal to combine user involvement and automated testing in the evaluation process. First a tree editor is presented that allows for the manual and semi-automated creation of match models which formalize the intended matching result. Second a benchmarking procedure is implemented which – given the intended match and the actual results of matching algorithms – automatically derives the number of a and b errors in a target-performance comparison. These results are valuable for drawing conclusions about the specific qualities of matching algorithms or for finding an adequate set of parameters for a configurable algorithm. KW - EMF Models KW - Model Comparison KW - Matching Algorithms KW - Evaluation Y1 - 2013 SN - 978-989-8565-42-6 U6 - https://doi.org/10.5220/0004310801010110 SN - 2184-4348 SP - 101 EP - 110 PB - SciTePress - Science and and Technology Publications ER - TY - CHAP A1 - Buchmann, Thomas A1 - Schwägerl, Felix T1 - Using Meta-code Generation to Realize Higher-order Model Transformations T2 - Proceedings of the 8th International Joint Conference on Software Technologies, July 29-31, 2013, in Reykjavík, Iceland, Vol. 1 N2 - Model-driven engineering is a wide-spread paradigm in modern software engineering. During the last couple of years, many tools and languages have been developed, which are especially designed for model transformations — a discipline which is needed in many model-driven engineering approaches. While most of the existing model-to-model tools and languages are tailored towards batch transformations for specific model instances, they lack support for generic transformation problems, where the metamodel is unknown beforehand. In this paper we present a two-step meta-code generation approach that derives a metamodel-specific modelto- model transformation from a model-to-text transformation. The approach has been successfully applied to the problem of product derivation in model-driven software product lines. KW - Model-driven Development KW - M2M Transformations KW - Model Transformations KW - Higher-order Transformations KW - Software Product Lines Y1 - 2013 SN - 978-989-8565-68-6 U6 - https://doi.org/https://doi.org/10.5220/0004522305360541 SP - 536 EP - 541 PB - SciTePress - Science and and Technology Publications ER - TY - JOUR A1 - Winter, Lina A1 - Artinger, Annalena A1 - Böck, Hendrik A1 - Ramakrishnan, Vignesh A1 - Reible, Bruno A1 - Albin, Jan A1 - Schüffler, Peter J. A1 - Raptis, Georgios A1 - Brochhausen, Christoph T1 - Developing a smart and scalable tool for histopathological education—PATe 2.0 JF - Journal of Pathology Informatics N2 - Digital microscopy plays a crucial role in pathology education, providing scalable and standardized access to learning resources. In response, we present PATe 2.0, a scalable redeveloped web-application of the former PATe system from 2015. PATe 2.0 was developed using an agile, iterative process and built on a microservices architecture to ensure modularity, scalability, and reliability. It integrates a modern web-based user interface optimized for desktop and tablet use and automates key workflows such as whole-slide image uploads and processing. Performance tests demonstrated that PATe 2.0 significantly reduces tile request times compared to PATe, despite handling larger tiles. The platform supports open formats like DICOM and OpenSlide, enhancing its interoperability and adaptability across institutions. PATe 2.0 represents a robust digital microscopy solution in pathology education enhancing usability, performance, and flexibility. Its design enables future integration of research algorithms and highlights it as a pivotal tool for advancing pathology education and research. Y1 - 2026 U6 - https://doi.org/10.1016/j.jpi.2025.100535 SN - 2153-3539 VL - 20 PB - Elsevier ER - TY - GEN A1 - Weber, Karsten T1 - Künstliche Intelligenz als vielschichtige Herausforderung Y1 - 2025 ER - TY - RPRT A1 - Bhardwaj, Prakhar A1 - Hauer, Franziska A1 - Mücke, Vanessa A1 - Dotter, Caroline A1 - Haug, Sonja A1 - Weikl, Simone A1 - Weber, Karsten T1 - Recording and understanding multi- and intermodal mobility - a review N2 - The transition to sustainable mobility requires detailed knowledge of actual mobility behavior. Recording mobility behavior through conventional, aggregated, or retrospective survey methods (e.g., counting stations, travel diaries) may yield incomplete insights. In addition, these methods are often expensive, prone to error, or not scalable. The aim of this literature review is to provide a systematic overview of the current state of the literature on recording and analysis of individual mobility data and, based on this, to identify possible research gaps and potential. The exploratory literature review includes social science surveys on multi- and intermodal mobility behavior, as well as an overview of possible ways to analyze travel data. The focus of the latter is on identifying relevant data sources and methodological approaches for segmentation, identification of transport mode, and trip purpose determination. Results from recent studies show that sensor-based data collection alone is not sufficient to fully and accurately map mobility behavior. One possible solution is a “best-of-both-worlds” approach that combines passive, automatic mobility data collection via smartphone sensors with targeted user corrections and additions (“human-in-the-loop”) within an app. The literature review shows that this approach yields the best data quality. Combining mobility surveys with passive collection of mobility data provides a comprehensive, accurate, and complete overview of mobility behavior. KW - multimodal mobility KW - mobility Y1 - 2025 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-87427 CY - Regensburg ER -