TY - JOUR A1 - Völlner, Florian A1 - Weber, Tim A. A1 - Weber, Markus A1 - Renkawitz, Tobias A1 - Dendorfer, Sebastian A1 - Grifka, Joachim A1 - Craiovan, Benjamin T1 - A simple method for determining ligament stiffness during total knee arthroplasty in vivo JF - Scientific Reports N2 - A key requirement in both native knee joints and total knee arthroplasty is a stable capsular ligament complex. However, knee stability is highly individual and ranges from clinically loose to tight. So far, hardly any in vivo data on the intrinsic mechanical of the knee are available. This study investigated if stiffness of the native ligament complex may be determined in vivo using a standard knee balancer. Measurements were obtained with a commercially available knee balancer, which was initially calibrated in vitro. 5 patients underwent reconstruction of the force-displacement curves of the ligament complex. Stiffness of the medial and lateral compartments were calculated to measure the stability of the capsular ligament complex. All force-displacement curves consisted of a non-linear section at the beginning and of a linear section from about 80 N onwards. The medial compartment showed values of 28.4 ± 1.2 N/mm for minimum stiffness and of 39.9 ± 1.1 N/mm for maximum stiffness; the respective values for the lateral compartment were 19.9 ± 0.9 N/mm and 46.6 ± 0.8 N/mm. A commercially available knee balancer may be calibrated for measuring stiffness of knee ligament complex in vivo, which may contribute to a better understanding of the intrinsic mechanical behaviour of knee joints. KW - Biomechanische Analyse KW - Kniegelenkband KW - Steifigkeit Y1 - 2019 U6 - https://doi.org/10.1038/s41598-019-41732-x VL - 9 SP - 1 EP - 8 PB - Nature ER - TY - JOUR A1 - Renkawitz, Tobias A1 - Weber, Tim A. A1 - Dullien, Silvia A1 - Woerner, Michael A1 - Dendorfer, Sebastian A1 - Grifka, Joachim A1 - Weber, Markus T1 - Leg length and offset differences above 5 mm after total hip arthroplasty are associated with altered gait kinematics JF - Gait & Posture N2 - We aimed to investigate the relationship between postoperative leg length/offset (LL/OS) reconstruction and gait performance after total hip arthroplasty (THA). In the course of a prospective randomized controlled trial, 60 patients with unilateral hip arthrosis received cementless THA through a minimally-invasive anterolateral surgical approach. One year post-operatively, LL and global OS restoration were analyzed and compared to the contralateral hip on AP pelvic radiographs. The combined postoperative limb length/OS reconstruction of the operated hip was categorized as restored (within 5 mm) or non-restored (more than 5 mm reduction or more than 5 mm increment). The acetabular component inclination, anteversion and femoral component anteversion were evaluated using CT scans of the pelvis and the femur. 3D gait analysis of the lower extremity and patient related outcome measures (HHS, HOOS, EQ-5D) were obtained pre-operatively, six months and twelve months post-operatively by an observer blinded to radiographic results. Component position of cup and stem was comparable between the restored and non-restored group. Combined LL and OS restoration within 5 mm resulted in higher Froude number (p < 0.001), normalized walking speed (p < 0.001) and hip range-of-motion (ROM) (p = 0.004) during gait twelve months postoperatively, whereas gait symmetry was comparable regardless of LL and OS reconstruction at both examinations. Clinical scores did not show any relevant association between the accuracy of LL or OS reconstruction and gait six/twelve months after THA. In summary, postoperative LL/OS discrepancies larger than 5 mm relate to unphysiological gait kinematics within the first year after THA. DRKS00000739, German Clinical Trials Register. KW - THA KW - Leg length KW - Offset KW - Gait analysis KW - Biomechanics Y1 - 2016 U6 - https://doi.org/10.1016/j.gaitpost.2016.07.011 VL - vol. 49 SP - 196 EP - 201 ER - TY - JOUR A1 - Renkawitz, Tobias A1 - Weber, Markus A1 - Springorum, H.-R. A1 - Sendtner, E. A1 - Woerner, Michael A1 - Ulm, K. A1 - Weber, Tim A1 - Grifka, Joachim T1 - Impingement-free range of motion, cup coverage and early clinical results between femur first navigation and conventional total hip arthroplasty: a randomised controlled trial JF - Journal of Bone & Joint Surgery N2 - We report the kinematic and early clinical results of a patient- and observer-blinded randomised controlled trial in which CT scans were used to compare potential impingement-free range of movement (ROM) and acetabular component cover between patients treated with either the navigated 'femur-first' total hip arthroplasty (THA) method (n = 66; male/female 29/37, mean age 62.5 years; 50 to 74) or conventional THA (n = 69; male/female 35/34, mean age 62.9 years; 50 to 75). The Hip Osteoarthritis Outcome Score, the Harris hip score, the Euro-Qol-5D and the Mancuso THA patient expectations score were assessed at six weeks, six months and one year after surgery. A total of 48 of the patients (84%) in the navigated 'femur-first' group and 43 (65%) in the conventional group reached all the desirable potential ROM boundaries without prosthetic impingement for activities of daily living (ADL) in flexion, extension, abduction, adduction and rotation (p = 0.016). Acetabular component cover and surface contact with the host bone were > 87% in both groups. There was a significant difference between the navigated and the conventional groups' Harris hip scores six weeks after surgery (p = 0.010). There were no significant differences with respect to any clinical outcome at six months and one year of follow-up. The navigated 'femur-first' technique improves the potential ROM for ADL without prosthetic impingement, although there was no observed clinical difference between the two treatment groups. KW - combined anteversion KW - computer-assisted orthopaedic surgery KW - THA KW - Hüftgelenkprothese KW - Operationstechnik KW - Computerunterstütztes Verfahren KW - Beweglichkeit Y1 - 2015 U6 - https://doi.org/10.1302/0301-620X.97B7.34729 VL - 97-B SP - 890 EP - 898 ER - TY - JOUR A1 - Weber, Markus A1 - Weber, Tim A. A1 - Woerner, Michael A1 - Craiovan, Benjamin A1 - Worlicek, Michael A1 - Winkler, Sebastian A1 - Grifka, Joachim A1 - Renkawitz, Tobias T1 - The impact of standard combined anteversion definitions on gait and clinical outcome within one year after total hip arthroplasty JF - International Orthopaedics N2 - Different target areas within the concept of combined cup and stem anteversion have been published for total hip arthroplasty (THA). We asked whether component positioning according to eight standard combined anteversion rules is associated with (1) more physiological gait patterns, (2) higher improvement of gait variables and (3) better clinical outcome after THA.In a prospective clinical study, 60 patients received cementless THA through an anterolateral MIS approach in a lateral decubitus position. Six weeks postoperatively, implant position was analysed using 3D-CT by an independent external institute. Preoperatively, six and 12 months postoperatively range of motion, normalized walking speed and hip flexion symmetry index were measured using 3D motion-capture gait analysis. Patient-related outcome measures (HHS, HOOS, EQ-5D) were obtained by an observer blinded to 3D-CT results. Eight combined anteversion definitions and Lewinnek's "safe zone" were evaluated regarding their impact on gait patterns and clinical outcome.Combined cup and stem anteversion according to standard combined anteversion definitions as well as cup placement within Lewinnek's "safe zone" did not influence range of motion, normalized walking speed and/or hip flexion symmetry index six and 12 months after THA. Similarly, increase of gait parameters within the first year after THA was comparable between all eight combined anteversion rules. Clinical outcome measures like HHS, HOOS and EQ-5D did not show any benefit for either of the combined anteversion definitions.Standard combined cup and stem anteversion rules do not improve postoperative outcome as measured by gait analysis and clinical scores within one year after THA. KW - Total hip athroplasty KW - Combined anteversion KW - Outcome KW - Gait analysis KW - Hüftgelenkprothese KW - Bewegungsanalyse KW - Gehen KW - Funktionelle Anatomie Y1 - 2015 U6 - https://doi.org/10.1007/s00264-015-2777-8 VL - 39 IS - 12 SP - 2323 EP - 2333 ER - TY - JOUR A1 - Weber, Markus A1 - Suess, Franz A1 - Jerabek, Seth A1 - Meyer, Matthias A1 - Grifka, Joachim A1 - Renkawitz, Tobias A1 - Dendorfer, Sebastian T1 - Kinematic pelvic tilt during gait alters functional cup position in total hip arthroplasty JF - Journal of Orthopaedic Research N2 - Static pelvic tilt impacts functional cup position in total hip arthroplasty (THA). In the current study we investigated the effect of kinematic pelvic changes on cup position. In the course of a prospective controlled trial postoperative 3D-computed tomography (CT) and gait analysis before and 6 and 12 months after THA were obtained in 60 patients. Kinematic pelvic motion during gait was measured using Anybody Modeling System. By fusion with 3D-CT, the impact of kinematic pelvic tilt alterations on cup anteversion and inclination was calculated. Furthermore, risk factors correlating with high pelvic mobility were evaluated. During gait a high pelvic range of motion up to 15.6° exceeding 5° in 61.7% (37/60) of patients before THA was found. After surgery, the pelvis tilted posteriorly by a mean of 4.0 ± 6.6° (p < .001). The pelvic anteflexion led to a mean decrease of −1.9 ± 2.2° (p < .001) for cup inclination and −15.1 ± 6.1° (p < .001) for anteversion in relation to the anterior pelvic plane (APP). Kinematic pelvic changes resulted in a further change up to 2.3° for inclination and up to 12.3° for anteversion. In relation to the preoperative situation differences in postoperative cup position ranged from −4.4 to 4.6° for inclination and from −7.8 to 17.9° for anteversion, respectively. Female sex (p < .001) and normal body weight (p < .001) correlated with high alterations in pelvic tilt. Kinematic pelvic changes highly impact cup anteversion in THA. Surgeons using the APP as reference should aim for a higher anteversion of about 15° due to the functional anteflexion of the pelvis during gait. KW - component position KW - gait analysis KW - kinematics KW - pelvic tilt KW - total hip arthroplasty KW - Hüftgelenkprothese KW - Haltungsfehler KW - Hüftgelenkpfanne Y1 - 2021 U6 - https://doi.org/10.1002/jor.25106 SN - 1554-527X VL - 40 IS - 4 SP - 846 EP - 853 PB - Wiley ER - TY - JOUR A1 - Weber, Markus A1 - Merle, Christian A1 - Nawabi, Danyal H. A1 - Dendorfer, Sebastian A1 - Grifka, Joachim A1 - Renkawitz, Tobias T1 - Inaccurate offset restoration in total hip arthroplasty results in reduced range of motion JF - Scientific Reports N2 - Offset restoration in total hip arthroplasty (THA) is associated with postoperative range of motion (ROM) and gait kinematics. We aimed to research into the impact of high offset (HO) and standard stems on postoperative ROM. 121 patients received cementless THA through a minimally-invasive anterolateral approach. A 360° hip ROM analysis software calculated impingement-free hip movement based on postoperative 3D-CTs compared to ROM values necessary for activities of daily living (ADL). The same model was then run a second time after changing the stem geometry between standard and HO configuration with the implants in the same position. HO stems showed higher ROM for all directions between 4.6 and 8.9° (p < 0.001) compared with standard stems but with high interindividual variability. In the subgroup with HO stems for intraoperative offset restoration, the increase in ROM was even higher for all ROM directions with values between 6.1 and 14.4° (p < 0.001) compared to offset underrestoration with standard stems. Avoiding offset underrestoration resulted in a higher amount of patients of over 20% for each ROM direction that fulfilled the criteria for ADL (p < 0.001). In contrast, in patients with standard stems for offset restoration ROM did increase but not clinically relevant by offset overcorrection for all directions between 3.1 and 6.1° (p < 0.001). Offset overcorrection by replacing standard with HO stems improved ROM for ADL in a low number of patients below 10% (p > 0.03). Patient-individual restoration of offset is crucial for free ROM in THA. Both over and underrestoration of offset should be avoided. KW - Adaptive clinical trial KW - Bone imaging Y1 - 2020 U6 - https://doi.org/10.1038/s41598-020-70059-1 VL - 10 IS - 13208 SP - 9 PB - Nature ER - TY - JOUR A1 - Yaghmaei, Emad A1 - van de Poel, Ibo A1 - Christen, Markus A1 - Gordijn, Bert A1 - Kleine, Nadine A1 - Loi, Michele A1 - Morgan, Gwenyth A1 - Weber, Karsten T1 - Canvas White Paper 1 Cybersecurity and Ethics JF - SSRN Electronic Journal N2 - This White Paper outlines how the ethical discourse on cybersecurity has developed in the scientific literature, which ethical issues gained interest, which value conflicts are discussed, and where the “blind spots” in the current ethical discourse on cybersecurity are located. The White Paper is based on an extensive literature with a focus on three reference domains with unique types of value conflicts: health, business/finance and national security. For each domain, a systematic literature search has been performed and the identified papers have been analysed using qualitative and quantitative methods. An important observation is that the ethics of cybersecurity not an established subject. In all domains, cybersecurity is recognized as being an instrumental value, not an end in itself, which opens up the possibility of trade-offs with different values in different spheres. The most prominent common theme is the existence of trade-offs and even conflicts between reasonable goals, for example between usability and security, accessibility and security, privacy and convenience. Other prominent common themes are the importance of cybersecurity to sustain trust (in institutions), and the harmful effect of any loss of control over data. Y1 - 2017 U6 - https://doi.org/10.2139/ssrn.3091909 VL - 18 IS - 4 PB - SSRN ER - TY - JOUR A1 - Christen, Markus A1 - Gordijn, Bert A1 - Weber, Karsten A1 - van de Poel, Ibo A1 - Yaghmaei, Emad T1 - A Review of Value-Conflicts in Cybersecurity BT - A Review of Value-Conflicts in Cybersecurity An assessment based on quantitative and qualitative literature analysis JF - Orbit Journal - An Online Journal for Responsible Research and Innovation in ICT N2 - Cybersecurity is of capital importance in a world where economic and social processes increasingly rely on digital technology. Although the primary ethical motivation of cybersecurity is prevention of informational or physical harm, its enforcement can also entail conflicts with other moral values. This contribution provides an outline of value conflicts in cybersecurity based on a quantitative literature analysis and qualitative case studies. The aim is to demonstrate that the security-privacy-dichotomy—that still seems to dominate the ethics discourse based on our bibliometric analysis—is insufficient when discussing the ethical challenges of cybersecurity. Furthermore, we want to sketch how the notion of contextual integrity could help to better understand and mitigate such value conflicts. Y1 - 2017 U6 - https://doi.org/10.29297/orbit.v1i1.28 VL - 1 IS - 1 SP - 1 EP - 19 ER - TY - JOUR A1 - Loi, Michele A1 - Christen, Markus A1 - Kleine, Nadine A1 - Weber, Karsten T1 - Cybersecurity in health BT - Disentangling value tensions JF - Journal of Information, Communication & Ethics in Society N2 - Purpose Cybersecurity in healthcare has become an urgent matter in recent years due to various malicious attacks on hospitals and other parts of the healthcare infrastructure. The purpose of this paper is to provide an outline of how core values of the health systems, such as the principles of biomedical ethics, are in a supportive or conflicting relation to cybersecurity. Design/methodology/approach This paper claims that it is possible to map the desiderata relevant to cybersecurity onto the four principles of medical ethics, i.e. beneficence, non-maleficence, autonomy and justice, and explore value conflicts in that way. Findings With respect to the question of how these principles should be balanced, there are reasons to think that the priority of autonomy relative to beneficence and non-maleficence in contemporary medical ethics could be extended to value conflicts in health-related cybersecurity. Research limitations/implications However, the tension between autonomy and justice, which relates to the desideratum of usability of information and communication technology systems, cannot be ignored even if one assumes that respect for autonomy should take priority over other moral concerns. Originality/value In terms of value conflicts, most discussions in healthcare deal with the conflict of balancing efficiency and privacy given the sensible nature of health information. In this paper, the authors provide a broader and more detailed outline. KW - Healthcare KW - Cybersecurity KW - Computer ethics KW - Bioethics KW - E-Health Y1 - 2019 U6 - https://doi.org/10.1108/JICES-12-2018-0095 VL - 17 IS - 2 SP - 229 EP - 245 ER - TY - JOUR A1 - Weber, Karsten A1 - Loi, Michele A1 - Christen, Markus A1 - Kleine, Nadine T1 - Digital Medicine, Cybersecurity, and Ethics BT - An Uneasy Relationship JF - American Journal of Bioethics Y1 - 2018 U6 - https://doi.org/10.1080/15265161.2018.1498935 VL - 18 IS - 9 SP - 52 EP - 53 PB - Taylor&Francis ER - TY - VIDEO A1 - Auer, Simon A1 - Reinker, Lukas A1 - Süß, Franz A1 - Kubowitsch, Simone A1 - Krutsch, Werner A1 - Weber, Markus A1 - Renkawitz, Tobias A1 - Dendorfer, Sebastian T1 - Webcast: Effect of mental demand on leg loading in highly dynamic motion N2 - Football players have a high risk of leg muscle injuries, especially when exposed to mental stress. Injuries to muscles of the thigh are common in amateur and professional football, representing almost a third of all injuries. These injuries occur primarily in non-contact situations and from overuse. They can lead to a range of costs, including financial costs associated with treatment as well as those associated with long-term recovery, and absence from training and/or competition. Further, there is a high risk of injury recurrence and subsequent injury. KW - Webcast KW - AnyBody KW - Stress KW - Football KW - Speedcourt Y1 - 2020 UR - https://www.youtube.com/watch?v=uSc_9XlnkaA ER - TY - JOUR A1 - Lenk, Christian A1 - Duttge, Gunnar A1 - Flatau, Laura A1 - Frommeld, Debora A1 - Poser, Wolfgang A1 - Reitt, Markus A1 - Schulze, Thomas A1 - Weber, Alexandra A1 - Zoll, Barbara T1 - A look into the future? Patients' and health care staff's perception and evaluation of genetic information and the right not to know JF - American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics N2 - The progress of medical genetics leads to a significant increase in genetic knowledge and a vast expansion of genetic diagnostics. However, it is still unknown how these changes will be integrated into medical practice and how they will change patients' and healthy persons' perception and evaluation of genetic diagnoses and genetic knowledge. Therefore, we carried out a comprehensive questionnaire survey with more than 500 patients, clients seeking genetic counseling, health care staff, and healthy persons (N = 523). The questionnaire survey covered detailed questions on the value of genetic diagnoses for the different groups of study participants, the right to know or not to know genetic diagnoses, possible differences between genetic and other medical diagnoses, and the practical use and implications of genetic knowledge with a special focus on hereditary neuropsychiatric diseases. A huge majority of the participants (90.7%) stated to have a right to learn every aspect of her or his genetic make-up. Similarly, study participants showed high interest (81.8%) in incidental health care findings-independent of whether the diseases are treatable or not. One can derive from the data outcome that study participants did not follow the implications of a "genetic exceptionalism" and often considered genetic findings as equivalent in relation to other medical diagnoses. KW - Attitude of Health Personnel KW - Female KW - Genetic Counseling/methods KW - Genetic Testing/ethics KW - Health Knowledge, Attitudes, Practice KW - Humans KW - Incidental Findings KW - Male KW - Middle Aged KW - Surveys and Questionnaires Y1 - 2019 U6 - https://doi.org/10.1002/ajmg.b.32751 VL - 180 IS - 8 SP - 576 EP - 588 PB - Wiley ER - TY - CHAP A1 - Christen, Markus A1 - Gordijn, Bert A1 - Weber, Karsten A1 - van de Poel, Ibo A1 - Yaghmaei, Emad ED - Oleksiewicz, Izabela T1 - A review of value-conflicts in cybersecurity T2 - Bezpieczeństwo informacyjne w wymiarze systemowym N2 - The growing complexity of the digital ecosystem in combination with increasing global risks has created the following dilemma. Overemphasizing cybersecurity may violate fundamental values like equality, fairness, freedom, or privacy but neglecting cybersecurity could undermine citizens’ trust and confidence in the digital infrastructure as well as in policy makers and state authorities. In order to increase our understanding of this dilemma, this contribution aims to provide an overview on value conflicts in cybersecurity based on a systematic review on the ethical, legal and technological literature on cybersecurity. It shall be emphasized that a focus on the opposition of cybersecurity vs. privacy is insufficient for understanding the ethical complexity of cybersecurity. KW - Computersicherheit KW - Rechnernetz KW - Literaturbericht Y1 - 2018 UR - https://www.researchgate.net/publication/327646764_A_review_of_value-conflicts_in_cybersecurity SP - 67 EP - 92 PB - Rambler Press CY - Warszawa ER - TY - GEN A1 - Scheppach, Markus W. A1 - Nunes, Danilo Weber A1 - Arizi, X. A1 - Rauber, David A1 - Probst, Andreas A1 - Nagl, Sandra A1 - Römmele, Christoph A1 - Meinikheim, Michael A1 - Palm, Christoph A1 - Messmann, Helmut A1 - Ebigbo, Alanna T1 - Procedural phase recognition in endoscopic submucosal dissection (ESD) using artificial intelligence (AI) T2 - Endoscopy N2 - Aims Recent evidence suggests the possibility of intraprocedural phase recognition in surgical operations as well as endoscopic interventions such as peroral endoscopic myotomy and endoscopic submucosal dissection (ESD) by AI-algorithms. The intricate measurement of intraprocedural phase distribution may deepen the understanding of the procedure. Furthermore, real-time quality assessment as well as automation of reporting may become possible. Therefore, we aimed to develop an AI-algorithm for intraprocedural phase recognition during ESD. Methods A training dataset of 364385 single images from 9 full-length ESD videos was compiled. Each frame was classified into one procedural phase. Phases included scope manipulation, marking, injection, application of electrical current and bleeding. Allocation of each frame was only possible to one category. This training dataset was used to train a Video Swin transformer to recognize the phases. Temporal information was included via logarithmic frame sampling. Validation was performed using two separate ESD videos with 29801 single frames. Results The validation yielded sensitivities of 97.81%, 97.83%, 95.53%, 85.01% and 87.55% for scope manipulation, marking, injection, electric application and bleeding, respectively. Specificities of 77.78%, 90.91%, 95.91%, 93.65% and 84.76% were measured for the same parameters. Conclusions The developed algorithm was able to classify full-length ESD videos on a frame-by-frame basis into the predefined classes with high sensitivities and specificities. Future research will aim at the development of quality metrics based on single-operator phase distribution. Y1 - 2024 U6 - https://doi.org/10.1055/s-0044-1783804 VL - 56 IS - S 02 SP - S439 PB - Thieme CY - Stuttgart ER - TY - GEN A1 - Scheppach, Markus W. A1 - Weber Nunes, Danilo A1 - Arizi, X. A1 - Rauber, David A1 - Probst, Andreas A1 - Nagl, Sandra A1 - Römmele, Christoph A1 - Palm, Christoph A1 - Messmann, Helmut A1 - Ebigbo, Alanna T1 - Single frame workflow recognition during endoscopic submucosal dissection (ESD) using artificial intelligence (AI) T2 - Endoscopy N2 - Aims  Precise surgical phase recognition and evaluation may improve our understanding of complex endoscopic procedures. Furthermore, quality control measurements and endoscopy training could benefit from objective descriptions of surgical phase distributions. Therefore, we aimed to develop an artificial intelligence algorithm for frame-by-frame operational phase recognition during endoscopic submucosal dissection (ESD). Methods  Full length ESD-videos from 31 patients comprising 6.297.782 single images were collected retrospectively. Videos were annotated on a frame-by-frame basis for the operational macro-phases diagnostics, marking, injection, dissection and bleeding. Further subphases were the application of electrical current, visible injection of fluid into the submucosal space and scope manipulation, leading to 11 phases in total. 4.975.699 frames (21 patients) were used for training of a video swin transformer using uniform frame sampling for temporal information. Hyperparameter tuning was performed with 897.325 further frames (6 patients), while 424.758 frames (4 patients) were used for validation. Results  The overall F1 scores on the test dataset for the macro-phases and all 11 phases were 0.96 and 0.90, respectively. The recall values for diagnostics, marking, injection, dissection and bleeding were 1.00, 1.00, 0.95, 0.96 and 0.93, respectively. Conclusions  The algorithm classified operational phases during ESD with high accuracy. A precise evaluation of phase distribution may allow for the development of objective quality metrics for quality control and training. Y1 - 2025 U6 - https://doi.org/10.1055/s-0045-1806324 VL - 57 IS - S 02 SP - S511 PB - Thieme CY - Stuttgart ER - TY - GEN A1 - Gschoßmann, Lukas A1 - Schedel, Valentin A1 - Süß, Franz A1 - Weber, Markus A1 - Pfingsten, Andrea A1 - Dendorfer, Sebastian T1 - Evaluating Knee Joint Loads Across Exercises and Activities of Daily Living to Personalize TKA Rehabilitation T2 - ISB 2025 - The XXX Congress of the International Society of Biomechanics, 27.-31. July 2025, Stockholm N2 - This study assessed knee joint loading during various physiotherapy exercises and activities of daily living in 30 healthy subjects. Results showed that lunges and squats caused the highest joint forces, while gait and stair activities also imposed substantial loads. These findings support datadriven exercise selection for personalized rehabilitation after total knee arthroplasty. Y1 - 2025 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-87252 ER -