TY - JOUR A1 - Metsch, P. A1 - Schmidt, Henrik A1 - Sindersberger, Dirk A1 - Kalina, K. A. A1 - Brummund, J. A1 - Auernhammer, Günter A1 - Monkman, Gareth J. A1 - Kästner, Markus T1 - Field-Induced Interactions in Magneto-Active Elastomers BT - A Comparison of Experiments and Simulations JF - Smart Materials and Structures N2 - In this contribution, field-induced interactions of magnetizable particles embedded into a soft elastomer matrix are analyzed with regard to the resulting mechanical deformations. By comparing experiments for two-, three- and four-particle systems with the results of finite element simulations, a fully coupled continuum model for magneto-active elastomers is validated with the help of real data for the first time. The model under consideration permits the investigation of magneto-active elastomers with arbitrary particle distances, shapes and volume fractions as well as magnetic and mechanical properties of the individual constituents. It thus represents a basis for future studies on more complex, realistic systems. Our results show a very good agreement between experiments and numerical simulations—the deformation behavior of all systems is captured by the model qualitatively as well as quantitatively. Within a sensitivity analysis, the influence of the initial particle positions on the systems' response is examined. Furthermore, a comparison of the full three-dimensional model with the often used, simplified two-dimensional approach shows the typical overestimation of resulting interactions in magneto-active elastomers. Y1 - 2020 U6 - https://doi.org/10.1088/1361-665X/ab92dc N1 - Corrigendum: Field-induced interactions in magneto-active elastomers—a comparison of experiments and simulations (2020 Smart Mater. Struct. 29 085026); https://doi.org/10.1088/1361-665X/abb98b VL - 29 IS - 8 SP - 1 EP - 10 PB - IOPscience ER - TY - GEN A1 - Hirmer, Marion A1 - Danilov, Sergey N. A1 - Giglberger, Stephan A1 - Putzger, Jürgen A1 - Niklas, Andreas A1 - Jäger, Andreas A1 - Hiller, Karl-Anton A1 - Schmalz, Gottfried A1 - Redlich, Britta A1 - Monkman, Gareth J. A1 - Ganichev, Sergey D. T1 - Spectroscopic Study of Human Teeth and Blood from Visible to Terahertz Frequencies for Clinical Diagnosis of Dental Pulp Vitality T2 - PACS, November 11, 2011 N2 - Transmission spectra of wet human teeth and dentin slices, together with blood of different flow rates were investigated. The measurements carried out over a wide spectral range, from visible light down to terahertz radiation. The results make it possible to find the optimum light frequency for an all-optical determination of pulpal blood flow and, consequently, for clinically diagnosis of tooth vitality. Y1 - 2011 ER - TY - CHAP A1 - Mayer, Matthias A1 - Forster, Eva A1 - Rabindranath, Raman A1 - Bentz, Alexander A1 - Böse, Holger A1 - Shamonin (Chamonine), Mikhail A1 - Monkman, Gareth J. T1 - Highly compliant Magneto-Active Polymers (MAPs) T2 - Actuator'11, Bremen, May 2011 Y1 - 2011 ER - TY - CHAP A1 - Schrimer, M A1 - Putz, Christoph A1 - Monkman, Gareth J. ED - McConnell, Lynn T1 - Boron-Silicone-Oxide Polymers T2 - Boron: advances in research and applications Y1 - 2021 SN - 9781685072315 SN - 1685072313 U6 - https://doi.org/10.52305/AFKU5564 SP - 117 EP - 179 PB - Nova Science Publishers CY - New York, NY ER - TY - JOUR A1 - Zimmermann, Klaus A1 - Chavez Vega, Jhohan Harvey A1 - Becker, Tatiana I. A1 - Witte, Hartmut A1 - Schilling, Cornelius A1 - Köhring, Sebastian A1 - Böhm, Valter A1 - Monkman, Gareth J. A1 - Prem, Nina A1 - Sindersberger, Dirk A1 - Lutz, I. I. A1 - Merker, Lukas T1 - An approach to a form-adaptive compliant gripper element based on magneto-sensitive elastomers with a bioinspired sensorized surface JF - Problems of Mechanics Y1 - 2019 SN - 1512-0740 VL - 75 IS - 2 SP - 23 EP - 38 PB - Georgian Technical University CY - Tbilisi ER - TY - GEN A1 - Chavez Vega, Jhohan Harvey A1 - Böhm, Valter A1 - Yin, J. A1 - Becker, Tatiana I. A1 - Köhring, Sebastian A1 - Monkman, Gareth J. A1 - Odenbach, Stefan A1 - Zimmermann, Klaus T1 - Field induced plasticity of magneto-sensitive elastomers for gripping technology applications T2 - 6th Colloquium of SPP 1681, Benediktbeuern, 26. - 28.09.2018 : Book of Abstracts Y1 - 2018 SP - 16 EP - 17 ER - TY - CHAP A1 - Drexler, C. A1 - Hirmer, Marion A1 - Danilov, Sergey N. A1 - Giglberger, Stephan A1 - Putzger, Jürgen A1 - Niklas, Andreas A1 - Jäger, Andreas A1 - Hiller, Karl-Anton A1 - Löffler, S. A1 - Schmalz, Gottfried A1 - Redlich, Britta A1 - Schulz, Irene A1 - Monkman, Gareth J. A1 - Ganichev, Sergey D. T1 - Infrared spectroscopy for clinical diagnosis of dental pulp vitality T2 - 37th International Conference on Infrared, Millimetre, and Terahertz Waves (IRMMW-THz 37), 23-28 September 2012 , Wollongong, Australia N2 - Transmission spectra of wet human teeth and dentin slices, together with blood of different flow rates were investigated over a wide spectral range, from visible to terahertz (THz) light. The results make it possible to find the optimum light frequency for an all-optical determination of pulpal blood flow and, consequently, for clinically diagnosis of tooth vitality. Y1 - 2012 U6 - https://doi.org/10.1109/IRMMW-THz.2012.6380091 PB - IEEE CY - Piscataway, NJ ER - TY - CHAP A1 - Forster, Eva A1 - Rabindranath, Raman A1 - Mayer, Matthias A1 - Bentz, Alexander A1 - Böse, Holger A1 - Shamonin (Chamonine), Mikhail A1 - Monkman, Gareth J. T1 - Characterization of ultra soft Magneto-Active Polymers (MAPs) T2 - Conference proceedings / INDUCTICA 2011, Berlin, Germany, 24 - 26 May Y1 - 2011 ER - TY - CHAP A1 - Nerlich, Michael A1 - Monkman, Gareth J. A1 - Füchtmeier, Bernd A1 - Egersdörfer, Stefan T1 - Development of a Robotic Navigation and Fracture Fixation System T2 - 1. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie (CURAC), Leipzig, 2002 Y1 - 2002 ER - TY - JOUR A1 - Broser, Christian A1 - Falter, Thomas A1 - Ławrowski, Robert Damian A1 - Altenbuchner, Amelie A1 - Vögele, Daniel A1 - Koss, Claus A1 - Schlamp, Matthias A1 - Dunnweber, Jan A1 - Steffens, Oliver A1 - Heckner, Markus A1 - Jaritz, Sabine A1 - Schiegl, Thomas A1 - Corsten, Sabine A1 - Lauer, Norina A1 - Guertler, Katherine A1 - Koenig, Eric A1 - Haug, Sonja A1 - Huber, Dominik A1 - Birkenmaier, Clemens A1 - Krenkel, Lars A1 - Wagner, Thomas A1 - Justus, Xenia A1 - Saßmannshausen, Sean Patrick A1 - Kleine, Nadine A1 - Weber, Karsten A1 - Braun, Carina N. A1 - Giacoppo, Giuliano A1 - Heinrich, Michael A1 - Just, Tobias A1 - Schreck, Thomas A1 - Schnabl, Andreas A1 - Gilmore, Amador Téran A1 - Roeslin, Samuel A1 - Schmid, Sandra A1 - Wellnitz, Felix A1 - Malz, Sebastian A1 - Maurial, Andreas A1 - Hauser, Florian A1 - Mottok, Jürgen A1 - Klettke, Meike A1 - Scherzinger, Stefanie A1 - Störl, Uta A1 - Heckner, Markus A1 - Bazo, Alexander A1 - Wolff, Christian A1 - Kopper, Andreas A1 - Westner, Markus A1 - Pongratz, Christian A1 - Ehrlich, Ingo A1 - Briem, Ulrich A1 - Hederer, Sebastian A1 - Wagner, Marcus A1 - Schillinger, Moritz A1 - Görlach, Julien A1 - Hierl, Stefan A1 - Siegl, Marco A1 - Langer, Christoph A1 - Hausladen, Matthias A1 - Schreiner, Rupert A1 - Haslbeck, Matthias A1 - Kreuzer, Reinhard A1 - Brückl, Oliver A1 - Dawoud, Belal A1 - Rabl, Hans-Peter A1 - Gamisch, Bernd A1 - Schmidt, Ottfried A1 - Heberl, Michael A1 - Gänsbauer, Bianca A1 - Bick, Werner A1 - Ellermeier, Andreas A1 - Monkman, Gareth J. A1 - Prem, Nina A1 - Sindersberger, Dirk A1 - Tschurtschenthaler, Karl A1 - Aurbach, Maximilian A1 - Dendorfer, Sebastian A1 - Betz, Michael A. A1 - Szecsey, Tamara A1 - Mauerer, Wolfgang A1 - Murr, Florian ED - Baier, Wolfgang T1 - Forschung 2018 T3 - Forschungsberichte der OTH Regensburg - 2018 KW - Forschung KW - Forschungsbericht Y1 - 2018 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-13826 SN - 978-3-9818209-5-9 CY - Regensburg ER - TY - RPRT A1 - Rabindranath, Raman A1 - Böse, Holger A1 - Probst, Jörn A1 - Schlunck, Günther A1 - Mayer, Matthias A1 - Forster, Eva A1 - Bentz, Alexander A1 - Shamonin (Chamonine), Mikhail A1 - Monkman, Gareth J. T1 - EAP mit magnetisch steuerbarer Elastizität zur Interaktion mit Bindegewebszellen MagElan BT - Teilvorhaben (HS-Regensburg) "Etablierung eines mechatronischen Systems zur (Magneto) Elastophorese von Bindegewebszellen" ; Schlussbericht ; Verbundprojekt "MagElan" ; Laufzeit des Vorhabens: 01.07.2009 - 30.10.2011 Y1 - 2012 N1 - Förderkennzeichen BMBF 13N10574 CY - Regensburg ER - TY - JOUR A1 - Dillinger, Andrea Elisabeth A1 - Weber, Gregor R. A1 - Mayer, Matthias A1 - Schneider, Magdalena A1 - Göppner, Corinna A1 - Ohlmann, Andreas A1 - Shamonin (Chamonine), Mikhail A1 - Monkman, Gareth J. A1 - Fuchshofer, Rudolf A1 - Keller, Kate A1 - Lozano, Diana C. A1 - Clark, Abbot T1 - CCN2/CTGF-A Modulator of the Optic Nerve Head Astrocyte JF - Frontiers in cell and developmental biology (Front Cell Dev Biol.) N2 - In primary open-angle glaucoma (POAG), a neurodegenerative disease of the optic nerve (ON) and leading cause of blindness, the optic nerve head (ONH) undergoes marked structural extracellular matrix (ECM) changes, which contribute to its permanent deformation and to degeneration of ON axons. The remodeling process of the ECM causes changes in the biomechanical properties of the ONH and the peripapillary sclera, which is accompanied by an increased reactivity of the resident astrocytes. The molecular factors involved in the remodeling process belong to the Transforming growth factor (TGF)-β superfamily, especially TGF-β2. In previous publications we showed that TGF-β2 induced ECM alterations are mediated by Cellular Communication Network Factor (CCN)2/Connective Tissue Growth Factor (CTGF) and recently we showed that CCN2/CTGF is expressed by astrocytes of the ON under normal conditions. In this study we wanted to get a better understanding of the function of CCN2/CTGF under normal and pathologic conditions. To this end, we analyzed the glial lamina and peripapillary sclera of CCN2/CTGF overexpressing mice and studied the effect of CCN2/CTGF and increasing substratum stiffness on murine ON astrocytes in vitro. We observed enhanced astrocyte reactivity in the ONH, increased ECM protein synthesis in the peripapillary sclera and increased Ccn2/Ctgf expression in the ONH during the pathologic development in situ. CCN2/CTGF treatment of primary murine ON astrocytes induced a higher migration rate, and increase of ECM proteins including fibronectin, elastin and collagen type III. Furthermore, the astrocytes responded to stiffer substratum with increased glial fibrillary acidic protein, vimentin, actin and CCN2/CTGF synthesis. Finally, we observed the reinforced appearance of CCN2/CTGF in the lamina cribrosa of glaucomatous patients. We conclude that reactive changes in ONH astrocytes, induced by the altered biomechanical characteristics of the region, give rise to a self-amplifying process that includes increased TGF-β2/CCN2/CTGF signaling and leads to the synthesis of ECM molecules and cytoskeleton proteins, a process that in turn augments the stiffness at the ONH. Such a scenario may finally result in a vicious circle in the pathogenesis of POAG. The transgenic CTGF-overexpressing mouse model might be an optimal model to study the chronic pathological POAG changes in the ONH. KW - astrocytes KW - extracellar matrix KW - glaucoma KW - glial lamina KW - growth factors KW - optic nerve KW - stiffness Y1 - 2022 U6 - https://doi.org/10.3389/fcell.2022.864433 VL - 10 PB - frontiers ER - TY - GEN A1 - Chavez Vega, Jhohan Harvey A1 - Böhm, Valter A1 - Scharff, Moritz A1 - Prem, Nina A1 - Monkman, Gareth J. A1 - Becker, Tatiana I. A1 - Günther, L. A1 - Alencastre, Jorge H. A1 - Grieseler, R. A1 - Zimmermann, Klaus T1 - Magneto-active elastomer as viscoelastic foundation material for artificial tactile sensors with tuneable properties T2 - Book of Abstracts of the 16th German Ferrofluid Workshop, Braunschweig, 18.-20.07.2018 Y1 - 2018 SP - 16 EP - 17 ER - TY - CHAP A1 - Füchtmeier, Bernd A1 - Egersdörfer, Stefan A1 - Tuma, G. A1 - Monkman, Gareth J. A1 - Nerlich, Michael ED - Nerlich, Michael ED - Schächinger, Ulrich T1 - Development of a Robotic Navigation and Fracture Fixation System T2 - Integration of Health Telematics into Medical Practice Y1 - 2003 SP - 43 EP - 49 PB - IOS Press ER - TY - JOUR A1 - Putz, Christoph A1 - Schirmer, Maximilian A1 - Sattler, Robert A1 - Monkman, Gareth J. T1 - Fabrication of Bisphenol-free Boron-Siloxane Polymers JF - Materials Chemistry and Physics N2 - Interest in the preparation of magnetoactive boron-siloxane polymers (MBP) has been stimulated by recent scientific developments. However, recent regulations have prohibited the inclusion of Bisphenol-A normally employed in the manufacture of commercially available products. In the following publication, two different routes for the preparation of magnetoactive borosiloxane polymers have been taken. First, the possibilities of obtaining homogeneous mixtures of magnetoactive polymers by mixing the magnetic particles with the polymer using solid CO2 (dry ice) and stirring (shearing) are investigated. In the course of the work, an approach for the preparation of reference materials of different viscosities was made to prove the transferability to other elastomers. This is then followed by a brief review of the reaction of the polymer with different solvents in relation to the mixing with particles. In manually kneaded compounds, dispersions ranging from 0.00004 to 0.004 particles per mm3 are common. The process described in this work resulted in agglomerations of no greater than 0.00004 particles per mm3 A possible synthesis route for bisphenol-free boron-siloxanes is then considered, in which for the polymer matrix, polydimethylsilanes (dichloro(methyl)silane), boric acid and iron(III)chloride are used for this purpose by polycondensation. Y1 - 2025 U6 - https://doi.org/10.1016/j.matchemphys.2025.130567 N1 - Corresponding author der OTH Regensburg: Gareth J. Monkman PB - Elsevier ET - Journal Pre-proof ER -