TY - JOUR A1 - Hirmer, Marion A1 - Danilov, Sergey N. A1 - Giglberger, Stephan A1 - Putzger, Jürgen A1 - Niklas, Andreas A1 - Jäger, Andreas A1 - Hiller, Karl-Anton A1 - Schmalz, Gottfried A1 - Redlich, Britta A1 - Schulz, Irene A1 - Monkman, Gareth J. A1 - Ganichev, Sergey D. T1 - Spectroscopic Study of Human Teeth and Blood from Visible to Terahertz Frequencies for Clinical Diagnosis of Dental Pulp Vitality JF - Journal of Infrared, Millimeter, and Terahertz Waves N2 - Transmission spectra of wet human teeth and dentin slices, together with blood of different flow rates were investigated. The measurements carried out over a wide spectral range, from visible light down to terahertz radiation. The results make it possible to find the optimum light frequency for an all-optical determination of pulpal blood flow and, consequently, for clinically diagnosis of tooth vitality. KW - Infrared and terahertz transmission KW - Dentin KW - Lentic or flowing blood KW - Dental pulp vitality Y1 - 2012 U6 - https://doi.org/10.1007/s10762-012-9872-3 SN - 1866-6906 VL - 33 SP - 366 EP - 375 PB - Springer ER - TY - JOUR A1 - Knörzer, S. A1 - Hiller, K-A A1 - Brandt, M. A1 - Niklas, Andreas A1 - Putzger, Jürgen A1 - Monkman, Gareth J. A1 - Danilov, Sergey N. A1 - Ganichev, Sergey D. A1 - Schulz, Irene A1 - Schmalz, Gottfried T1 - Detection of pulsed blood flow through a molar pulp chamber and surrounding tissue in vitro JF - Journal of Clinical Oral Investigations N2 - OBJECTIVES Due to severe limitations of dental pulp sensitivity tests, the direct recording of pulsed blood flow, using photoplethysmography (PPG), has been proposed. In vivo evaluation is methodologically difficult and in vitro models have hitherto been adversely influenced by shortcomings in emulating the in vivo situation. Consequently, the aim of this study was to test an improved data acquisition system and to use this configuration for recording pulsed blood in a new model. MATERIALS AND METHODS We introduced a PPG signal detection system by recording signals under different blood flow conditions at two wavelengths (625 and 940 nm). Pulsed blood flow signals were measured using an in vitro model, containing a molar with a glass pulp and a resin socket, which closely resembled in vivo conditions with regard to volumetric blood flow, pulp anatomy, and surrounding tissue. RESULTS The detection system showed improved signal strength without stronger blanketing of noise. On the tooth surface, it was possible to detect signals emanating from pulsed blood flow from the glass pulp and from surrounding tissue at 625 nm. At 940 nm, pulp derived signals were recorded, without interference signals from surrounding tissue. CONCLUSION The PPG-based method has the potential to detect pulsed blood flow in small volumes in the pulp and (at 625 nm) also in adjacent tissues. CLINICAL RELEVANCE The results show the need for clear differentiation of the spatial origins of blood flow signals of any vitality test method to be applied to teeth. KW - Dental Pulp KW - Dental Pulp Cavity KW - Dental Pulp Test KW - Laser-Doppler Flowmetry KW - Molar Y1 - 2019 U6 - https://doi.org/10.1007/s00784-018-2530-y VL - 23 IS - 3 SP - 1121 EP - 1132 PB - Springer Nature ER - TY - CHAP A1 - Niklas, Andreas A1 - Hiller, Karl-Anton A1 - Jäger, Andreas A1 - Brandt, M. A1 - Putzger, Jürgen A1 - Ermer, C. A1 - Schulz, Irene A1 - Monkman, Gareth J. A1 - Giglberger, Stephan A1 - Hirmer, Marion A1 - Danilov, Sergey N. A1 - Ganichev, Sergey D. A1 - Schmalz, Gottfried ED - Arenholt-Bindslev, Dorthe ED - Schmalz, Gottfried T1 - In vitro optical detection of simulated blood pulse in a human tooth pulp model T2 - Biocompatibility of Dental Materials Y1 - 2013 PB - Springer CY - Berlin ; Heidelberg ER - TY - GEN A1 - Hirmer, Marion A1 - Danilov, Sergey N. A1 - Giglberger, Stephan A1 - Putzger, Jürgen A1 - Niklas, Andreas A1 - Jäger, Andreas A1 - Hiller, Karl-Anton A1 - Schmalz, Gottfried A1 - Redlich, B. A1 - Monkman, Gareth J. A1 - Ganichev, Sergey D. T1 - Spectroscopic Study of Human Teeth and Blood from Visible to Terahertz Frequencies for Clinical Diagnosis of Dental Pulp Vitality T2 - PACS, November 11, 2011 N2 - Transmission spectra of wet human teeth and dentin slices, together with blood of different flow rates were investigated. The measurements carried out over a wide spectral range, from visible light down to terahertz radiation. The results make it possible to find the optimum light frequency for an all-optical determination of pulpal blood flow and, consequently, for clinically diagnosis of tooth vitality. Y1 - 2011 ER - TY - CHAP A1 - Drexler, C. A1 - Hirmer, Marion A1 - Danilov, Sergey N. A1 - Giglberger, Stephan A1 - Putzger, Jürgen A1 - Niklas, Andreas A1 - Jäger, Andreas A1 - Hiller, K.A A1 - Löffler, S. A1 - Schmalz, Gottfried A1 - Redlich, B. A1 - Schulz, Irene A1 - Monkman, Gareth J. A1 - Ganichev, Sergey D. T1 - Infrared spectroscopy for clinical diagnosis of dental pulp vitality T2 - 37th International Conference on Infrared, Millimetre, and Terahertz Waves (IRMMW-THz 37), 23-28 September 2012 , Wollongong, Australia N2 - Transmission spectra of wet human teeth and dentin slices, together with blood of different flow rates were investigated over a wide spectral range, from visible to terahertz (THz) light. The results make it possible to find the optimum light frequency for an all-optical determination of pulpal blood flow and, consequently, for clinically diagnosis of tooth vitality. Y1 - 2012 U6 - https://doi.org/10.1109/IRMMW-THz.2012.6380091 PB - IEEE CY - Piscataway, NJ ER - TY - CHAP A1 - Schulz, Irene A1 - Putzger, Jürgen A1 - Niklas, Andreas A1 - Brandt, M. A1 - Jäger, Andreas A1 - Hardt, A. A1 - Knörzer, S. A1 - Hiller, Karl-Anton A1 - Löffler, S. A1 - Schmalz, Gottfried A1 - Danilov, Sergey N. A1 - Giglberger, Stephan A1 - Hirmer, Marion A1 - Ganichev, Sergey D. A1 - Monkman, Gareth J. T1 - PPG signal acquisition and analysis on in vitro tooth model for dental pulp vitality assessmen T2 - 2nd Applied Research Conference 2012 (ARC 2012), 25./26. June 2012, Nuremberg Y1 - 2012 SP - 142 EP - 146 PB - Shaker-Verlag CY - Aachen ER -