TY - CHAP A1 - Horner, Marc A1 - Dendorfer, Sebastian A1 - Kiis, Arne A1 - Lawrenchuk, Mike A1 - Verma, Gunjan T1 - A Patient based simulation workflow for orthopedic device design and analysis T2 - SBC Ortho Workshop, June 2011 Y1 - 2011 ER - TY - CHAP A1 - Andersen, Michael Skipper A1 - de Zee, Mark A1 - Dendorfer, Sebastian A1 - MacWilliams, Bruce A1 - Rasmussen, John T1 - Validation of a detailed lower extremity model based on the Klein Horsman data set T2 - Proceedings of the 12th International Symposium on Computer Simulation in Biomechanics (ISB 2009), July 2nd - 4th 2009, Cape Town, South Africa Y1 - 2009 SP - 27 EP - 28 ER - TY - CHAP A1 - Robie, Bruce A1 - Rasmussen, John A1 - Christensen, Soeren Toerholm A1 - Dendorfer, Sebastian T1 - Herniation Induces 55% Increase in Load of Key Stabilizing Muscle – Impact on Herniation Treatment Devices? T2 - Spine Arthoplasty Society Meeting, New Orleans, 2010 Y1 - 2010 ER - TY - CHAP A1 - Dendorfer, Sebastian A1 - Carbes, S. A1 - Rasmussen, John T1 - The influence of muscle forces on biomechanical fracture fixation simulations – from in-vivo forces to tissue strains T2 - World Congress on Medical Physics and Biomedical Engineering, 7 - 12, 2009, Munich Y1 - 2009 ER - TY - CHAP A1 - Dendorfer, Sebastian A1 - Rasmussen, John T1 - The influence of in-vivo muscle forces on the stress distribution in a vertebral body during activities of daily living T2 - Eurospine Warsaw, Poland 2009 Y1 - 2009 ER - TY - CHAP A1 - Dendorfer, Sebastian T1 - How much iron to pump? The determination of muscle forces for activities of daily living T2 - DGU, Berlin, 2008 Y1 - 2008 ER - TY - GEN A1 - Gschoßmann, Lukas A1 - Dendorfer, Sebastian T1 - Personalized Rehabilitation after Total Knee Arthroplasty T2 - 32nd Annual Meeting of the European Orthopaedic Research Society (EORS 2024), 18 - 20 September 2024, Aalborg Y1 - 2024 ER - TY - CHAP A1 - Melzner, Maximilian A1 - Engelhardt, Lucas A1 - Havelkova, Leonard A1 - Simon, Ulrich A1 - Dendorfer, Sebastian T1 - A new musculoskeletal AnyBody detailed hand model validated by electromyography T2 - 16th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (CMBBE) 2019, New York City, USA N2 - The AnyBody™ Modeling System (AMS) [1], is an universally used musculoskeletal simulation software using inverse dynamics. Until now, no complete human hand model is known in the AMS. Also considering other musculoskeletal software platforms, just one detailed entire hand model is recently published [2] but is only based on one subject. The aim of this work is to implement a full detailed hand model for the AMS including all extrinsic and intrinsic muscles using data by the UWB gained through an anatomical study of ten cadaver hands. Y1 - 2019 UR - https://www.researchgate.net/publication/336944957_A_NEW_MUSCULOSKELETAL_ANYBODY_DETAILED_HAND_MODEL_VALIDATED_BY_ELECTROMYOGRAPHY ER - TY - GEN A1 - Auer, Simon A1 - Krutsch, Werner A1 - Renkawitz, Tobias A1 - Kubowitsch, Simone A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Effect of mental demand on leg loading in highly dynamic motion T2 - AnyBody online Webinar, Oct 2020 N2 - Football players have a high risk of leg muscle injuries, especially when exposed to mental stress. Injuries to muscles of the thigh are common in amateur and professional football, representing almost a third of all injuries. These injuries occur primarily in non-contact situations and from overuse. They can lead to a range of costs, including financial costs associated with treatment as well as those associated with long-term recovery, and absence from training and/or competition. Further, there is a high risk of injury recurrence and subsequent injury. Y1 - 2020 ER - TY - JOUR A1 - Auer, Simon A1 - Krutsch, Werner A1 - Renkawitz, Tobias A1 - Kubowitsch, Simone A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Kognitiver Stress führt zu unphysiologisch erhöhten Kniebelastungen im Profifußball JF - Sports Orthopaedics and Traumatology Y1 - 2020 U6 - https://doi.org/10.1016/j.orthtr.2020.04.122 VL - 36 IS - 2 SP - 202 EP - 203 PB - Elsevier ER - TY - CHAP A1 - Süß, Franz A1 - Kubowitsch, Simone A1 - Rasmussen, John A1 - Verkerke, Gijsbertus Jacob A1 - Dendorfer, Sebastian T1 - The influence of cognitive stress on muscle activation and spinal disc load T2 - European Society of Biomechanics meeting 2019, Vienna, Austria Y1 - 2019 UR - https://owncloud.tuwien.ac.at/index.php/s/dovqqcj02VeZHze ER - TY - GEN A1 - Aurbach, Maximilian A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - The impact of the hill type muscle model on the glenohumeral joint reaction force T2 - 16th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (CMBBE) 2019, New York City, USA Y1 - 2019 ER - TY - CHAP A1 - Kubowitsch, Simone A1 - Dendorfer, Sebastian T1 - Psychologie und Biomechanik – Integrierte Betrachtung von Muskelrekrutierung BT - Erkenntnisse und Ableitungen für Biofeedback T2 - Jahrestagung der Deutschen Gesellschaft für Biofeedback e. V., Regensburg, 2018 Y1 - 2018 ER - TY - GEN A1 - Dendorfer, Sebastian T1 - Virtuelle Modelle der oberen Extremität T2 - 22. Interdisziplinäres Symposium Medizin-Physiotherapie-Sportwissenschaften, 22.-23.11.2019, Regensburg, Germany Y1 - 2019 ER - TY - CHAP A1 - Aurbach, Maximilian A1 - Wagner, Kilian A1 - Süß, Franz A1 - Dendorfer, Sebastian ED - Badnjevic, Almir T1 - Implementation and Validation of Human Kinematics Measured Using IMUs for Musculoskeletal Simulations by the Evaluation of Joint Reaction Forces T2 - CMBEBIH 2017, Proceedings of the International Conference on Medical and Biological Engineering 2017, Sarajevo, Bosnia and Herzegovina N2 - The gold standard for the analysis of human kinematics and kinetics is a camera-based motion capture system in combination with force measurement platforms. Alternatively, inertial measurement units can be utilized to obtain human kinematics, while ground reaction forces are computed from full body dynamics. This setup represents a system independent from the spatial confinement of a gait laboratory. The aim of this study is the comparison of the two methods by the investigation of lower limb kinematics and the resulting joint reaction forces within the ankle-, knee- and hip joints. For this purpose, human motion during gait was captured simultaneously by both measurement techniques. 13 trials from 8 different test subjects were evaluated in total. IMU data was processed with a quaternion based Kalman Filter. The data sets were implemented into a musculoskeletal simulation program in order to drive a virtual human body model. Each sensor was aligned to the gravitational and magnetic field vectors of the earth. The angles of flexions, extensions and rotations were analyzed to determine kinematic differences. Joint reaction forces defined kinetic dissimilarities. The overall kinematic differences of both models yielded root mean square errors of 7.62°, 6.02°, 4.95°, 2.79°, 2.38° and 3.56° for ankle flexion, subtalar eversion, knee flexion, hip external rotation, hip abduction and hip flexion, respectively. The proximo-distal differences in force peaks between the models yielded overall for the ankle, 57.33 %Bodyweight(BW) ± 46.86 %BW (16.66 %(Maximum peak to peak) ± 13.62 %) for the knee 37.09 %BW ± 29.33 %BW (17.65 % ± 15.44 %) and 32.03 %BW ± 24.33 %BW (15.6 % ± 12.54 %) for the hip. The overall outcome of this work investigated an approach independent of the common setup of the gait laboratory, thus enabling a cheaper and more flexible technology as an alternative. However, kinematic and thus kinetic differences remain rather large. Future work aims to improve the contact criterion for the calculation of the ground reaction forces and the implementation of a full-body calibration algorithm for the IMU system in order to counteract magnetic field disturbances. KW - Inertial Measurement Units KW - Multibody Simulation KW - Musculoskeletal Simulation KW - AnyBody KW - Motion Capture KW - Bewegungsapparat KW - Biomechanik KW - Motion Capturing KW - Mehrkörpersimulation KW - Ground Reaction Force Prediction KW - Gait KW - IMU KW - Joint Reaction Forces Y1 - 2017 U6 - https://doi.org/10.1007/978-981-10-4166-2_31 VL - Vol. 62 SP - 205 EP - 211 PB - Springer CY - Singapore ER - TY - CHAP A1 - Hammer, Joachim A1 - Dendorfer, Sebastian T1 - Cyclic loading and microstructure of cancellous bone T2 - Journal of Biomechanics Y1 - 2008 U6 - https://doi.org/10.1016/S0021-9290(08)70409-3 VL - 41 IS - Suppl. 1, July 2008 SP - S410 ER - TY - CHAP A1 - Dendorfer, Sebastian T1 - Biomechanical evaluation and optimisation of countermeasure exercises T2 - ESA/ESTEC Bedrest Strategy Workshop, Noordwijk, NL, 2009 Y1 - 2009 ER - TY - GEN A1 - Adler, Ina A1 - Förstl, Nikolas A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Biomechanical exposition of the factors influencing the pelvic floor muscle activity T2 - ESB 2024, 29th Congress of the European Society of Biomechanics, 30 June-3 July 2024, Edinburgh, Scotland N2 - Introduction About 40 % of the women worldwide suffer from Pelvic Floor Dysfunctions [1]. In previous studies, musculoskeletal simulations helped to understand and facilitate the complex issues of musculoskeletal disorders in several different branches [2, 3]. A fundamental prerequisite for the generation of these models is to have a basic understanding of the stresses acting on the pelvic floor. The aim of this study is to investigate the biomechanical factors influencing the activity of the pelvic floor muscles by establishing a parameterised model. Methods To identify the factors that affect the pelvic floor muscles, the process is divided into several stages. The first step is to investigate the loads acting on the pelvic floor. For this, a simplified sagittal cross-sectional model of the upper body is analysed. The discretization of the abdominal cavity is presented with resulting force vectors representing the organs in the abdominal and pelvic region, the tensile force of the structures that fixate the organs as well as the intraabdominal pressure. A second step is the examination of the basic mechanics of the pelvic floor muscles. As the functional anatomy of these muscles demonstrate differences compared to other muscle groups [4], the understanding of how they differ is crucial for the construction of musculoskeletal models. After a static examination of loads on a simplified muscle model, an extended model including the physiological properties of a muscle must be involved in the considerations. Therefore, the influence of parameters such as the ideal muscle strength and fibre length, as well as elasticity or passive stiffness of the elements must be taken into account. The influencing factors of the variables can be analysed in a simplified pelvic floor muscle model by systematically changing the parameters. Results The process of analysing the factors influencing the activity of the pelvic floor muscles follows two main strategies. The review of the effects of the whole body identifies the forces acting on the pelvic floor muscles and effect their activity. With the examination of the basic mechanics of a simplified pelvic floor muscle model a better understanding is achieved of how the pelvic floor muscles absorb the loads acting in the body. Discussion This process results in the main influence factors on the activity of the pelvic floor. The consequent parameters form the basis for a biomechanically justified construction of musculoskeletal simulation models of the pelvic floor. Nevertheless, it must be considered, that these mechanical studies represent simplifications of the reality. References 1. Wang et al, Front Public Health, 10:975829, 2022. 2. Bulat et al., Curr Sports Med Rep, 18(6):210-216, 2019 3. Melzner et al., Eur J Obstet Gynecol Reprod Biol, 264:306-313, 2021 4. Ashton-Miller et al., Ann N Y Acad Sci, 1101:266-96, 2007 Y1 - 2024 ER - TY - VIDEO A1 - Auer, Simon A1 - Reinker, Lukas A1 - Süß, Franz A1 - Kubowitsch, Simone A1 - Krutsch, Werner A1 - Weber, Markus A1 - Renkawitz, Tobias A1 - Dendorfer, Sebastian T1 - Webcast: Effect of mental demand on leg loading in highly dynamic motion N2 - Football players have a high risk of leg muscle injuries, especially when exposed to mental stress. Injuries to muscles of the thigh are common in amateur and professional football, representing almost a third of all injuries. These injuries occur primarily in non-contact situations and from overuse. They can lead to a range of costs, including financial costs associated with treatment as well as those associated with long-term recovery, and absence from training and/or competition. Further, there is a high risk of injury recurrence and subsequent injury. KW - Webcast KW - AnyBody KW - Stress KW - Football KW - Speedcourt Y1 - 2020 UR - https://www.youtube.com/watch?v=uSc_9XlnkaA ER - TY - JOUR A1 - Dendorfer, Sebastian A1 - Melzner, Maximilian T1 - Rückenschmerzen bei Geburtshelfer:innen. Die Haltung macht's. JF - Deutsche Hebammen-Zeitschrift N2 - Für Mutter und Kind konnte das Risiko der Geburt durch die Weiterentwicklung der Medizin drastisch reduziert werden. Doch wie ist es um das Wohl derer bestellt, die die Gebärende unterstützen? Eine Studie der Ostbayerischen Technischen Hochschule Regensburg hat sich mit den muskuloskelettalen Beschwerden von Geburtshelfer:innen auseinandergesetzt Y1 - 2022 UR - https://ip.staudeverlag.de/de/profiles/c3962f735915-elwin-staude-verlag-kiosk-bc/editions/dhz-11-2022/pages/page/32 SN - 0012-026X VL - 74 IS - 11 SP - 60 EP - 62 PB - Staude CY - Hannover ER - TY - JOUR A1 - Visscher, Rosa A1 - Wyss, C. A1 - Singh, Navrag B. A1 - Taylor, William R. A1 - Dendorfer, Sebastian A1 - Rutz, E. A1 - Brunner, Reinald T1 - Influence of TAL-TATS surgery on energy production of Tricepts Surae - A musculoskeletal modeling evaluation JF - Gait & Posture Y1 - 2020 U6 - https://doi.org/10.1016/j.gaitpost.2020.08.090 VL - 81 IS - Suppl. 1 SP - 381 EP - 382 PB - Elsevier ER - TY - GEN A1 - Gschoßmann, Lukas A1 - Stein, Leonhard A1 - Dendorfer, Sebastian T1 - Subject Specific Scaling Of Muscle Strengths In The Lower Extremity For Musculoskeletal Models T2 - ESB 2024, 29th Congress of the European Society of Biomechanics, 30 June-3 July 2024, Edinburgh, Scotland Y1 - 2024 ER - TY - CHAP A1 - Suess, Franz A1 - Melzner, Maximilian A1 - Dendorfer, Sebastian T1 - Towards ergonomics working - machine learning algorithms and musculoskeletal modeling T2 - IOP Conference Series: Materials Science and Engineering N2 - Ergonomic workplaces lead to fewer work-related musculoskeletal disorders and thus fewer sick days. There are various guidelines to help avoid harmful situations. However, these recommendations are often rather crude and often neglect the complex interaction of biomechanical loading and psychological stress. This study investigates whether machine learning algorithms can be used to predict mechanical and stress-related muscle activity for a standardized motion. For this purpose, experimental data were collected for trunk movement with and without additional psychological stress. Two different algorithms (XGBoost and TensorFlow) were used to model the experimental data. XGBoost in particular predicted the results very well. By combining it with musculoskeletal models, the method shown here can be used for workplace analysis but also for the development of real-time feedback systems in real workplace environments. Y1 - 2021 U6 - https://doi.org/10.1088/1757-899X/1208/1/012001 SN - 1757-899X N1 - Corresponding author: Sebastian Dendorfer VL - 1208 PB - IOP Publishing ER - TY - CHAP A1 - Aurbach, Maximilian A1 - Jungtäubl, Dominik A1 - Spicka, Jan A1 - Dendorfer, Sebastian T1 - EMG-based validation of musculoskeletal models considering crosstalk T2 - World Congress Biomechanics, 28-30 June 2018, Dublin N2 - BACKGROUND: Validation and verification of multibody musculoskeletal models sEMG is a difficult process because of the reliability of sEMG data and the complex relationship of muscle force and sEMG. OBJECTIVE: This work aims at comparing experimentally recorded and simulated muscle activities considering a numerical model for crosstalk. METHODS: For providing an experimentally derived reference data set, subjects were performing elevations of the arm, where the activities of the contemplated muscle groups were measured by sEMG sensors. Computed muscle activities were further processed and transformed into an artificial electromyographical signal, which includes a numerical crosstalk model. In order to determine whether the crosstalk model provides a better agreement with the measured muscle activities, the Pearson correlation coefficient has been computed as a qualitative way of assessing the curve progression of the data sets. RESULTS: The results show an improvement in the correlation coefficient between the experimental data and the simulated muscle activities when taking crosstalk into account. CONCLUSIONS: Although the correlation coefficient increased when the crosstalk model was utilized, it is questionable if the discretization of both, the crosstalk and the musculoskeletal model, is accurate enough. Y1 - 2018 U6 - https://doi.org/10.1109/BIOMDLORE.2018.8467211 ER - TY - GEN A1 - Suess, Franz A1 - Melzner, Maximilian A1 - Dendorfer, Sebastian T1 - Towards Ergonomic working - machine learning algorithms and musculoskeletal modeling T2 - RIM 2021, 13th International Scientific Conference on Manufacturing Engineering, 29 Sept. - 1 Oct 2021, Sarajevo, Bosnia and Herzegovina Y1 - 2021 ER - TY - RPRT A1 - Putzer, Michael A1 - Rasmussen, John A1 - Ehrlich, Ingo A1 - Gebbeken, Norbert A1 - Dendorfer, Sebastian ED - Baier, Wolfgang T1 - Muskuloskelettale Simulation zur Untersuchung des Einflusses geometrischer Parameter der Wirbelkörper auf die Belastung der Lendenwirbelsäule T2 - Forschungsbericht 2013 / Ostbayerische Technische Hochschule Regensburg Y1 - 2013 UR - https://doi.org/10.35096/othr/pub-799 SP - 60 EP - 61 CY - Regensburg ER - TY - GEN A1 - Dendorfer, Sebastian T1 - Sturz- und Frakturprävention: Use it or lose it! T2 - 10 Jahre Alterstraumatologie Caritas Krankenhaus St. Josef Regensburg Y1 - 2024 ER - TY - CHAP A1 - Dendorfer, Sebastian A1 - Englert, Carsten T1 - Forces on a clavicles midshaft fracture and influence of fracture type T2 - AO Symposium, Regensburg, 2009 Y1 - 2009 ER - TY - JOUR A1 - Förstl, Nikolas A1 - Süß, Franz A1 - Englert, Carsten A1 - Dendorfer, Sebastian T1 - Design of a reverse shoulder implant to measure shoulder stiffness during implant component positioning JF - Medical Engineering & Physics N2 - To avoid dislocation of the shoulder joint after reverse total shoulder arthroplasty, it is important to achieve sufficient shoulder stability when placing the implant components during surgery. One parameter for assessing shoulder stability can be shoulder stiffness. The aim of this research was to develop a temporary reverse shoulder implant prototype that would allow intraoperative measurement of shoulder stiffness while varying the position of the implant components. Joint angle and torque measurement techniques were developed to determine shoulder stiffness. Hall sensors were used to measure the joint angles by converting the magnetic flux densities into angles. The accuracy of the joint angle measurements was tested using a test bench. Torques were determined by using thin-film pressure sensors. Various mechanical mechanisms for variable positioning of the implant components were integrated into the prototype. The results of the joint angle measurements showed measurement errors of less than 5° in a deflection range of ±15° adduction/abduction combined with ±45° flexion/extension. The proposed design provides a first approach for intra-operative assessment of shoulder stiffness. The findings can be used as a technological basis for further developments. Y1 - 2023 U6 - https://doi.org/10.1016/j.medengphy.2023.104059 N1 - Corresponding author: Sebstian Dendorfer VL - 121 PB - Elsevier ET - Journal Pre-proof ER - TY - CHAP A1 - Muehling, M. A1 - Englert, Carsten A1 - Dendorfer, Sebastian T1 - Influence of biceps tenotomy and tenodesis on post-operative shoulder strength T2 - Jahrestagung der Deutschen Gesellschaft für Biomechanik, March 2017, Hannover, Germany Y1 - 2017 ER - TY - CHAP A1 - Englert, Carsten A1 - Müller, F. A1 - Dendorfer, Sebastian T1 - Einfluss der Muskelkräfte, des Bewegungsausmaßes und der Bruchform auf die Kraftübertragung des Implantat-Knochenverbundes am Beispiel der Claviculafraktur im mittleren Drittel T2 - 17. Jahreskongress der Deutschen Vereinigung für Schulter- und Ellenbogenchirurgie (DVSE), Rosenheim 2010 N2 - Fragestellung Es soll in dieser Computersimulationsstudie untersucht werden, wie der Osteosyntheseverbund Platte mit Schrauben im Verbund mit einer im mittleren Drittel gebrochenen Clavicula durch das Bewegungsausmaß in vivo belastet ist. Was sind die grundlegenden Kräfte die auf Clavicula und Implantat wirken und welchen Einfl uss hat die Bruchform. Methodik Die Muskel- und Gelenkkräfte sowie die Belastung des Implantatverbundes wurden mit einer muskuloskelletalen Simulationssoftware (AnyBody Technology, V.4) berechnet. Hierfür wurden mit einem komplexen Model des menschlichen Körpers folgende Bewegungen analysiert: eine Flexion von 160° und Abduktion 160° mit einem Gewicht von 2 kg in der Hand. Aus CT-Patientendaten wurden zwei dreidimensionale Modelle des Clavicula-Implantat Verbundes gebildet, die sich in der Frakturform unterscheiden (Querfraktur und vertikale Fraktur). In beiden Modellen wurde eine Claviculaosteosynthese in superiorer Position mit einer 6 Loch LCP mit 2 Schrauben pro Hauptfragment verwendet. Die Materialeigenschaften wurden aus der Dichte des Materials sowie aus Literaturdaten verwendet. Die Muskel- und Gelenkkräfte aus der muskuloskelletalen Berechnung wurden auf das Finite Elemente Modell übertragen und die Spannungen und Dehnungen des Implantat-Knochenverbundes wurden berechnet. Ergebnisse Es zeigte sich, dass die simulierte in vivo Belastung stark abhängig vom Flexionswinkel ist. Das Implantat ist in der superioren Lage auf Biegung belastet, welche maximale Werte im Überschulterniveau erreicht. Die Bruchform mit anatomischer Reposition und Kontakt der Hauptfragmente zueinander führt zu einer deutlichen Entlastung des Osteosyntheseverbundes im Vergleich zu einer Bruchform mit vertikaler Fraktur. Schlussfolgerung Aus den Analysen ist eine Positionierung der Plattenosteosynthese für die im mittleren Drittel frakturierte Clavicula in anterior-superiorer Lage wünschenswert. Die anatomische Reposition entlastet den Osteosyntheseverbund und sollte möglichst erreicht werden. Die Nachbehandlung sollte ein Bewegungsausmaß für den Arm für 4 Wochen für einfache Bruchformen auf 70° Flexion und Abduktion limitieren und für komplexe Bruchformen diese Limitierung ausgedehnt werden. Y1 - 2010 ER - TY - JOUR A1 - Pfeifer, Christian A1 - Müller, Michael A1 - Prantl, Lukas A1 - Berner, Arne A1 - Dendorfer, Sebastian A1 - Englert, Carsten T1 - Cartilage labelling for mechanical testing in T-peel configuration JF - International Orthopaedics N2 - PURPOSE: The purpose of this study was to find a suitable method of labelling cartilage samples for the measurement of distraction distances in biomechanical testing. METHODS: Samples of bovine cartilage were labelled using five different methods: hydroquinone and silver nitrate (AgNO3), potassium permanganate (KMnO4) with sodium thiosulphate (Na2S2O3), India ink, heat, and laser energy. After the labelling, we analysed the cartilage samples with regard to cytotoxity by histochemical staining with ethidiumbromide homodimer (EthD-1) and calcein AM. Furthermore, we tested cartilages labelled with India ink and heat in a T-peel test configuration to analyse possible changes in the mechanical behaviour between marked and unlabelled samples. RESULTS: Only the labelling methods with Indian ink or a heated needle showed acceptable results in the cytotoxity test with regard to labelling persistence, accuracy, and the influence on consistency and viability of the chondrocytes. In the biomechanical T-peel configuration, heat-labelled samples collapsed significantly earlier than unlabelled samples. CONCLUSION: Labelling bovine cartilage samples with Indian ink in biomechanical testing is a reliable, accurate, inexpensive, and easy-to-perform method. This labelling method influenced neither the biomechanical behaviour nor the viability of the tissue compared to untreated bovine cartilage. KW - Bovine cartilage KW - Cartilage samples KW - Indian ink KW - T-peel configuration KW - Method labeling KW - Knorpel KW - Rind KW - Kennzeichnung KW - Tinte KW - Biomechanik KW - Prüfung Y1 - 2012 U6 - https://doi.org/10.1007/s00264-011-1468-3 VL - 36 IS - 7 SP - 1493 EP - 1499 PB - Springer ER - TY - JOUR A1 - Förstl, Nikolas A1 - Adler, Ina A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Technologies for Evaluation of Pelvic Floor Functionality: A Systematic Review JF - Sensors N2 - Pelvic floor dysfunction is a common problem in women and has a negative impact on their quality of life. The aim of this review was to provide a general overview of the current state of technology used to assess pelvic floor functionality. It also provides literature research of the physiological and anatomical factors that correlate with pelvic floor health. This systematic review was conducted according to the PRISMA guidelines. The PubMed, ScienceDirect, Cochrane Library, and IEEE databases were searched for publications on sensor technology for the assessment of pelvic floor functionality. Anatomical and physiological parameters were identified through a manual search. In the systematic review, 114 publications were included. Twelve different sensor technologies were identified. Information on the obtained parameters, sensor position, test activities, and subject characteristics was prepared in tabular form from each publication. A total of 16 anatomical and physiological parameters influencing pelvic floor health were identified in 17 published studies and ranked for their statistical significance. Taken together, this review could serve as a basis for the development of novel sensors which could allow for quantifiable prevention and diagnosis, as well as particularized documentation of rehabilitation processes related to pelvic floor dysfunctions. Y1 - 2024 U6 - https://doi.org/10.3390/s24124001 N1 - Die Preprint-Version ist ebenfalls in diesem Repositorium verzeichnet unter: https://opus4.kobv.de/opus4-oth-regensburg/frontdoor/index/index/docId/7306 VL - 24 IS - 12 PB - MDPI ER - TY - GEN A1 - Englert, Carsten A1 - Dendorfer, Sebastian T1 - Einfluss der Rotatorenmanschette auf die glenohumerale Stabilität T2 - 20. Intensivkurs Schulterendoprothetik Marburg KW - Biomechanik Y1 - 2022 CY - Marburg ER - TY - GEN A1 - Förstl, Nikolas A1 - Adler, Ina A1 - Suess, Franz A1 - Čechová, Hana A1 - Jansová, Magdalena A1 - Cimrman, Robert A1 - Vychytil, Jan A1 - Dendorfer, Sebastian T1 - Workflow for the development of a non-invasive feedback device to assess pelvic floor contractions T2 - ESB 2024, 29th Congress of the European Society of Biomechanics, 30 June-3 July 2024, Edinburgh, Scotland N2 - Introduction Pelvic floor disorders affect about 40% of women worldwide [1]. Pelvic floor muscle (PFM) training is both a preventive and a therapeutic intervention. Current PFM training devices are invasive and have little scientific evidence. The idea is to develop a noninvasive feedback device to assess adequate PFM contraction. Therefore, evidence-based female musculoskeletal models, non-invasive data acquisition, sensor technology and artificial intelligence (AI) will be combined. This work presents the workflow to achieve such a feedback device and describes the interaction of the technologies used. Methods Exercises that induce PFM contractions have been evaluated and defined. Motion capture of these exercises will provide input for female musculoskeletal models. A combination of biomechanical rigid body and FEM simulations will be used to estimate PFM contractions. In addition, a non-invasive sensor will measure pelvic floor activity. The simulated and measured data will be used to develop an AI model that provides feedback on PFM contractions based on non-invasive data collection. Results The AMMR (AnyBody Managed Model Repository) of the AnyBody modelling system (AMS, Aalborg, Denmark) serves as the initial model for performing inverse dynamic simulations of the exercises. To calculate the PFM forces, the full-body model must be supplemented with the relevant pelvic floor structures and a mass model of the internal organs. A modified abdominal pressure model must also be incorporated. The AMS calculates the PFM activities caused by the internal organ loads and the generated abdominal pressure during the exercises. The muscle activities are transferred to a FEM model of the female pelvic floor (SfePy, simple finite elements in Python). The identical pelvic floor structures were integrated into the FEM model as in the AMS. Active PFM contractions can be simulated using the FEM model. Movement of the coccyx due to PFM contractions has been reported in the literature [2,3]. Therefore, a noninvasive coccyx motion sensor will be developed to provide additional information on PFM contractions. The measured data (coccyx motion sensor, motion capture) and the simulation results of the models will be combined to create an AI feedback model using Python. The final feedback device will consist of the AI model and the developed coccyx motion sensor, which can reproduce the resulting PFM contractions based on the sensor data and simplified motion tracking. Discussion The creation of the AMS and the FEM model is a prerequisite for the development of the feedback device. The relevant structures in the models are located inside the body. This limits the ability to observe the structures during the exercises, which can lead to difficulties in model validation. The development of a user-friendly sensor with sufficient measuring accuracy of the coccyx motion is another challenge. Nevertheless, the workflow represents a promising approach to develop a noninvasive feedback system to assess PFM contraction. References 1. Wang et al, Front Public Health, 10:975829, 2022. 2. Bø et al, Neurourol Urodyn, 20:167–174, 2001. 3. Fujisaki et al, J Phys Ther Sci, 30:544–548, 2018. Acknowledgements This work was supported by the project no. BYCZ01-014 of the Program INTERREG Bavaria – Czechia 2021–2027. Y1 - 2024 ER - TY - GEN A1 - Förstl, Nikolas A1 - Süß, Franz A1 - Englert, Carsten A1 - Dendorfer, Sebastian T1 - Design of a reverse shoulder implant to measure shoulder stiffness during implant component positioning T2 - Book of abstracts / ESB 2023, 28th Congress of the European Society of Biomechanics, 9-12 July 2023, Maastricht, The Netherlands. N2 - Introduction Dislocation of the shoulder joint is one of the more common complications after reverse total shoulder arthroplasty [1], which is often associated with malposition of the prosthetic components [2]. Therefore, achieving sufficient shoulder stability should not be neglected when positioning the implant components. One parameter for assessing shoulder stability can be shoulder stiffness. The aim of this work is to develop a reverse shoulder implant prototype that allows intraoperative measurement of shoulder stiffness while varying the position of the implant components. The measured stiffness could provide a quantitative statement regarding the optimal positioning of the implant components, which can be adjusted accordingly in the final reverse shoulder prosthesis. Methods To measure the stiffness of the shoulder joint, it is necessary to record the joint angles and the torques generated during movement. The changes in the rotation angles were measured using 3D hall sensors and magnets. The magnets were placed under the humerosocket, and the hall sensors were integrated into the glenosphere. The strength of the magnetic field was used to determine the position of the humerosocket in relation to the glenosphere. The accuracies of the angle measurements were tested using a test bench. Three thin film pressure sensors were used to record forces at different points under the humerosocket. To obtain a force value from the sensor signal, the sensors were calibrated using a load cell. The variation of the implant components positions was integrated into the prototype implant through different constructive mechanisms to adjust the stiffness of the shoulder joint. Results In the range of ±45° flexion/extension combined with ±15° adduction/abduction, the joint position could be determined with sufficient accuracy (error e ≤ 5°). The areas near the combined maximum deflections of ±45° flexion/extension and ±45° adduction/abduction indicate the greatest deviation from the target angle. The force values of the thin film sensors enable the calculation of moments around two axes. As variable component position parameters, the tray offset, the neck-shaft angle and the humerus version were integrated into the implant prototype. Discussion Ideally, the accuracy of the angle measurements should only depend on the amount of deflection and not on the direction of deflection. The asymmetric behavior indicates a deviation from the correct positioning of the hall sensors. The application of a calibration matrix could compensate for the measurement errors and could demonstrate the potential of the new method for joint angle measurements. The accuracy of the torque measurements and the functionality of the mechanical arresting mechanisms must be investigated in further studies. Overall, the developed measurement method can help to avoid malpositioning of the implant components in reverse total shoulder arthroplasty. References 1. Clark et al, J Shoulder and elbow surgery, 21:36-41 2012. 2. Randelli et al, J Musculoskeletal surgery, 98:15-18, 2014. Y1 - 2023 UR - https://esbiomech.org/conference/archive/2023maastricht/332.pdf ER - TY - GEN A1 - Melzner, Maximilian A1 - Ismail, Khaled M. A1 - Rušavý, Zdeněk A1 - Kališ, Vladimír A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Musculoskeletal Lower Back Load of Accoucheurs During Delivery T2 - 26th Congress of the European Society of Biomechanics, July 11-14, 2021, Milan, Italy N2 - With the progress in modern medicine, it was possible to significantly reduce the risks of birth for mother and child. One aspect that has received less attention so far is the risk of injury to the accoucheurs (obstetricians and midwives) during the birth process. Indeed, studies indicate that 92% of midwives suffer from musculoskeletal disorders, with the lower back being the main cause of complaints (72%). The aim of this study was to investigate two commonly used postural techniques used by accoucheurs during childbirth and to analyze the resulting load on the lower back using the AnyBodyTM musculoskeletal simulation software. Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-20208 CY - Milan ER - TY - JOUR A1 - Melzner, Maximilian A1 - Ismail, Khaled M. A1 - Rušavy, Zdenek A1 - Kališ, Vladimír A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Musculoskeletal lower back load of accoucheurs during childbirth – A pilot and feasibility study JF - European Journal of Obstetrics & Gynecology and Reproductive Biology N2 - Introduction: Back problems represent one of the leading causes of accouchers' work-related musculoskeletal morbidities. The correct execution of birth-related maneuvers including manual perineal protection is crucial not only for the mother and child but also for obstetricians and midwives to reduce any strain on their musculoskeletal system. Therefore, the overall aim of this study was to test the feasibility of determining the effect of different accouchers' postures (standing and kneeling) on their musculoskeletal system. Methods: The biomechanical analysis is based on musculoskeletal simulations that included motion recordings of real deliveries as well as deliveries conducted on a birthing simulator. These simulations were then used to determine individual joints' loads. Results: In the kneeling posture, both a low intra-operator variability and a lower average maximum load of the lower back was observed. For the standing position the spine load was reduced by pivoting the elbow on the accouchers' thigh, which in turn was associated with a significantly greater load on the shoulder joint. Conclusion: The study demonstrated the feasibility of our technique to assess joints loads. It also provided initial data indicating that a posture that reduces spinal flexion and tilt, achieved in this study by the kneeling, can significantly reduce the strain on the practitioner's musculoskeletal system. KW - lower back load KW - Accoucheur KW - Musculoskeletal simulation Y1 - 2021 U6 - https://doi.org/10.1016/j.ejogrb.2021.07.042 IS - 264 SP - 306 EP - 313 PB - Elsevier ER - TY - JOUR A1 - Kieninger, Martin A1 - Schneider, Corinna A1 - Auer, Simon A1 - Reinker, Lukas A1 - Adler, Ina A1 - Dendorfer, Sebastian A1 - Rosenberger, Johanna A1 - Popp, Daniel A1 - Eissnert, Christoph A1 - Ludsteck, Dominik A1 - Cyrus, Christopher A1 - Hoffmann, Johannes A1 - Morag, Sarah A1 - Graf, Bernhard A1 - Kieninger, Bärbel T1 - Transport von schwer verletzten Traumapatienten im Rettungswagen mit und ohne starre Halsorthese: vergleichende biomechanische Messungen JF - Die Anaesthesiologie N2 - Hintergrund: Der tatsächliche Stellenwert der prähospitalen Immobilisation der Halswirbelsäule (HWS) bei schwer verletzten Traumapatienten ist weiterhin unklar. In Anbetracht möglicher negativer Implikationen durch das Anbringen einer starren HWS-Orthese muss deren Anwendung während der gesamten prähospitalen Phase kritisch hinterfragt werden. Ziel der Arbeit: Es sollten vergleichende biomechanische Messungen zur Beweglichkeit der HWS bei Immobilisation mittels Vakuummatratze mit und ohne zusätzliches Anbringen einer starren HWS-Orthese nach Lagerung auf der Trage durchgeführt werden. Material und Methoden: Die Bewegungen der HWS beim Ein- und Ausladeprozess in einen modernen RTW sowie während der Fahrt entlang eines vordefinierten Parkours wurden mit einem Motion-Capture-System aufgezeichnet. Die Probandin, an der die Messungen durchgeführt wurden, wurde auf einer Vakuummatratze mit der Möglichkeit zur seitlichen Fixierung des Kopfes sowie Kinn- und Stirngurt auf einer elektrohydraulischen Fahrtrage immobilisiert. Bei der einen Hälfte der Versuche erfolgte die zusätzliche Immobilisation der HWS mittels starrer Orthese, bei der anderen wurde auf die Anwendung einer HWS-Orthese verzichtet. Ergebnisse: Statistisch signifikante Unterschiede ergaben sich nur bei einigen biomechanischen Parametern in der sagittalen Ebene (Flexion und Extension). Für die anderen Bewegungsrichtungen (axiale Rotation, laterale Beugung) wurden keine signifikanten Unterschiede für die gemessenen Parameter ermittelt. Generell wurden sowohl bei den Versuchen mit HWS-Orthese als auch ohne HWS-Orthese nur sehr geringe Winkelauslenkungen (im Mittel bei axialer Rotation und Flexion/Extension im Bereich von einem bis 2 Grad, bei der lateralen Beugung höchstens 3 Grad) gemessen. Schlussfolgerung: Bei einer korrekt durchgeführten Immobilisation mittels einer Vakuummatratze mit der Möglichkeit zur seitlichen Stabilisierung des Kopfes sowie Kinn- und Stirngurt auf einer elektrohydraulischen Fahrtrage mit Beladesystem ergeben sich für den Ein- und Ausladeprozess sowie während der Fahrt in einem modernen RTW mit luftgefederter Tragenlagerung und Luftfederung der Hinterachse keine relevanten Vorteile bezüglich der Einschränkung der Bewegung der HWS durch die zusätzliche Verwendung einer starren HWS-Orthese. T2 - Transport of severely injured trauma patients in an ambulance with and without a rigid neck orthosis: comparative biomechanical measurements KW - Notfallmedizin KW - Immobilisation KW - Vakuummatratze KW - Zervikalstütze · KW - Halswirbelsäule Y1 - 2024 U6 - https://doi.org/10.1007/s00101-024-01462-w VL - 73 IS - 10 SP - 668 EP - 675 PB - Springer Nature ER - TY - JOUR A1 - Rusavy, Zdenek A1 - Cechova, Hana A1 - Dendorfer, Sebastian A1 - Kalis, Vladimir A1 - Ismail, Khaled M. T1 - Is the Finnish grip tight enough? A manometric study of two manual perineal protection techniques JF - Acta Obstetricia et Gynecologica Scandinavica Y1 - 2025 U6 - https://doi.org/10.1111/aogs.15033 VL - 104 IS - 2 SP - 423 EP - 425 PB - Wiley ER - TY - JOUR A1 - Morag, Sarah A1 - Kieninger, Martin A1 - Eissnert, Christoph A1 - Auer, Simon A1 - Dendorfer, Sebastian A1 - Popp, Daniel A1 - Hoffmann, Johannes A1 - Kieninger, Bärbel T1 - Comparison of different techniques for prehospital cervical spine immobilization: Biomechanical measurements with a wireless motion capture system JF - PLOS ONE Y1 - 2023 U6 - https://doi.org/10.1371/journal.pone.0292300 VL - 18 IS - 11 SP - 1 EP - 14 PB - PLOS CY - San Francisco, California ER - TY - JOUR A1 - Hoenicka, Markus A1 - Lehle, Karla A1 - Jacobs, V. R. A1 - Dendorfer, Sebastian A1 - Kostorz, A. A1 - Schmid, F. X. A1 - Birnbaum, D. E. T1 - Mechanical and seeding properties of human umbilical vein – a potential scaffold for a tissue-engineered vessel graft JF - The Thoracic and Cardiovascular Surgeon N2 - Objectives: The mechanical properties and seeding with endothelial cells were investigated in fresh and cryopreserved human umbilical vein. Methods: Human umbilical veins (HUV) were frozen in Euro-Collins/1M DMSO at –1°C/min and stored in liquid nitrogen. Stress-strain relationships of fresh and thawed veins were determined in an uniaxial tension-testing rig. HUV endothelial cells (HUVEC) were seeded onto denuded HUV under static conditions and grown for 3d. Luminal surfaces were analyzed by scanning electron microscopy. Calcein-stained cells were seeded hyperconfluently to determine the cell retention capacity of fresh and cryopreserved veins. Results: The stress-strain relationships of HUV followed a biphasic pattern typical for natural vessels. Neither the failure stress (2.71±0.36 vs. 3.25±0.97 N, n=3) nor the displacement required to achieve failure (9.73±0.9 vs. 7.43±2.07mm, n=3) were altered by cryopreservation. The burst pressure was estimated as approx. 1000mm Hg within the limitations of the uniaxial model. HUVEC seeded onto denuded HUV formed patches (at 9E3 cells per cm2) or an almost confluent endothelium (at 3E4 cells per cm2) within three days. The capacity to retain seeded HUVEC of denuded HUV was not altered by cryopreservation (1.15±0.08E5 vs. 1.26±0.14E5 cells per cm2, n=6). Conclusions: The burst pressure of HUV seems to be sufficiently high for the human arterial circulation and is not altered by cryopreservation. HUVEC can establish a confluent endothelium on denuded HUV. Therefore HUV appears to be a suitable storable scaffold for vascular tissue engineering. KW - Nabelvene KW - Tissue Engineering Y1 - 2007 U6 - https://doi.org/10.1055/s-2007-967592 VL - 55 IS - S 1 SP - P_37 PB - Thieme ER - TY - JOUR A1 - Lazarev, Igor A. A1 - Riabokon, P. V. A1 - Haller, M. A1 - Dendorfer, Sebastian T1 - Effect of the Displacement of Calcaneal Bone Peripheral Fragment in its Fracture on the Function of the Three-Headed Calf Muscle JF - TRAUMA N2 - In the structure of musculoskeletal injuries, calcaneal fractures account for up to 4 % of all skeletal fractures and up to 60 % of hindfoot fractures. The effect of the displacement of the peripheral fragment of the calcaneus on the calf muscles’s reaction forces at the time of the adoption of the simplified squatting position was investigated by modeling in AnyBody Modeling System 6.0 software. M.gastrocnemius (lateralis et medialis) in the initial phase of motion in all variants of the peripheral fragment displacement did not develop sufficient muscular effort in comparison to the intact calcaneus. M.soleus medialis et lateralis showed significant increase in muscle activity rates in the initial phase of motion (41.87 ± 1.90 H and 52.07 ± 2.10 H) before reaching its maximum values, as compared with those of the intact calcaneus. In the final phase of the movement, upon muscle reaches its maximum length, muscular strength indicators of the m.soleus returned to their original values or were significantly below them. The decline in muscle strength was due to shortening of the moment arm or muscle excursion in case of convergence of muscle attachment points. When the peripheral fragment is displaced, due to putting down the heel to the surface of the support in terms of anatomical muscle lengthening, it takes extra effort to achieve rest length and its maximum power. In all types of the displacement of the peripheral fragment, the function of three-headed calf muscle is disturbed with involvement of additional muscular effort and energy expenditure. This fact should motivate the surgeon on the need for accurate repositioning of bone fragments in calcaneal fractures with the displacement of the peripheral fragment. Y1 - 2016 U6 - https://doi.org/10.22141/1608-1706.2.16.2015.80247 VL - 16 IS - 2 SP - 20 EP - 24 PB - Zaslavsky ER - TY - JOUR A1 - Lazarev, Igor A. A1 - Ryabokon, P.V. A1 - Haller, M. A1 - Dendorfer, Sebastian T1 - Effect of the fractured calcaneus's peripheral fragment displacement on the triceps surae function JF - ЖУРНАЛ «ТРАВМА» Ukrainian Trauma Journal Y1 - 2015 VL - 2, TOM 16 ER - TY - JOUR A1 - Dendorfer, Sebastian A1 - Maier, Hans Jürgen A1 - Hammer, Joachim T1 - Fatigue damage in cancellous bone: an experimental approach from continuum to micro scale JF - Journal of the Mechanical Behavior of Biomedical Materials N2 - Repeated loadings may cause fatigue fractures in bony structures. Even if these failure types are known, data for trabecular bone exposed to cyclic loading are still insufficient as the majority of fatigue analyses on bone concentrate on cortical structures. Despite its highly anisotropic and inhomogeneous structure, trabecular bone is treated with continuum approaches in fatigue analyses. The underlying deformation and damage mechanism within trabecular specimens are not yet sufficiently investigated. In the present study different types of trabecular bone were loaded in monotonic and cyclic compression. In addition to the measurement of integral specimen deformations, optical deformation analysis was employed in order to obtain strain distributions at different scale levels, from the specimens' surface to the trabeculae level. These measurements allowed for the possibility of linking the macroscopic and microscopic mechanical behaviour of cancellous bone. Deformations were found to be highly inhomogeneous across the specimen. Furthermore strains were found to already localise at very low load levels and after few load cycles. Microcracks in individual trabeculae were induced in the very early stage of cyclic testing. The results provide evidence of the capability of the method to supply essential data on the failure behaviour of individual trabeculae in future studies. KW - Knochen KW - Spongiosa KW - Ermüdungsbruch KW - Fatigue KW - Cancellous bone KW - Deformation behaviour KW - Damage KW - Measurement and testing KW - Mechanical behaviour Y1 - 2009 U6 - https://doi.org/10.1016/j.jmbbm.2008.03.003 VL - 2 IS - 1 SP - 113 EP - 119 ER - TY - CHAP A1 - Dendorfer, Sebastian A1 - Maier, Hans Jürgen A1 - Hammer, Joachim T1 - How do age and anisotropy affect the fatigue behaviour of cancellous bone? T2 - Medicine Meets Engineering N2 - The fatigue behaviour of materials is of particular interest for the failure prediction of materials and structures exposed to cyclic loading. For trabecular bone structures only a few sets of lifetime data have been reported in the literature and structural measures are commonly not considered. The influence of load contributions not aligned with the main physiological axis remains unclear. Furthermore age effects on the fatigue behaviour are not well described. In the present study, different groups of human vertebral cancellous bone were exposed to cyclic compression. The inital modulus and therefore lifetimes were found to be highly dependent on age. The decrease in both with increasing age was much more pronounced in specimens which were not aligned with the main physiological axis. This implies that old bone is much more sensitive to (cyclic) failure loads in general but particularly to loads which are not coincident with the physiological main axis. KW - Knochenbruch KW - Spongiosa KW - Alter KW - Anisotropie Y1 - 2008 SP - 68 EP - 74 PB - IOS Press ER - TY - JOUR A1 - Hölscher, Thomas A1 - Weber, Tim A. A1 - Lazarev, Igor A. A1 - Englert, Carsten A1 - Dendorfer, Sebastian T1 - The influence of rotator cuff tears on glenohumeral stability during abduction tasks JF - Journal of Orthopaedic Research N2 - One of the main goals in reconstructing rotator cuff tears is the restoration of glenohumeral joint stability, which is subsequently of utmost importance in order to prevent degenerative damage such as superior labral anterior posterior (SLAP) lesion, arthrosis, and malfunction. The goal of the current study was to facilitate musculoskeletal models in order to estimate glenohumeral instability introduced by muscle weakness due to cuff lesions. Inverse dynamics simulations were used to compute joint reaction forces for several static abduction tasks with different muscle weakness. Results were compared with the existing literature in order to ensure the model validity. Further arm positions taken from activities of daily living, requiring the rotator cuff muscles were modeled and their contribution to joint kinetics computed. Weakness of the superior rotator cuff muscles (supraspinatus; infraspinatus) leads to a deviation of the joint reaction force to the cranial dorsal rim of the glenoid. Massive rotator cuff defects showed higher potential for glenohumeral instability in contrast to single muscle ruptures. The teres minor muscle seems to substitute lost joint torque during several simulated muscle tears to maintain joint stability. Joint instability increases with cuff tear size. Weakness of the upper part of the rotator cuff leads to a joint reaction force closer to the upper glenoid rim. This indicates the comorbidity of cuff tears with SLAP lesions. The teres minor is crucial for maintaining joint stability in case of massive cuff defects and should be uprated in clinical decision-making. KW - Abduction tasks KW - Glenohumeral stability KW - Musculoskeletal Modeling KW - Muscle weakness KW - Rotator cuff tears KW - Rotatorenmanschettenriss KW - Schultergelenk KW - Stabilität Y1 - 2016 U6 - https://doi.org/10.1002/jor.23161 VL - 34 IS - 9 SP - 1628 EP - 1635 ER - TY - JOUR A1 - Englert, Carsten A1 - Angele, Peter A1 - Fierlbeck, J. A1 - Dendorfer, Sebastian A1 - Schubert, T. A1 - Müller, R. A1 - Lienhard, S. A1 - Zellner, Johannes A1 - Nerlich, Michael A1 - Neumann, Carsten T1 - Conductive bone substitute material with variable antibiotic delivery JF - Der Unfallchirurg N2 - A new bone substitute, consisting of hydroxylapatite and calcium sulphate, was prepared in two formulations and analysed for its mechanical strength and antibiotic elution.The bone substitute PerOssal has osteoconductive and degradable properties. The material has a built-in capillary structure, which results in an immediate fluid uptake. Antibiotics absorbed to the bone substitute resulted in a prolonged release rate. Mechanical strength was investigated by an unconfined compression test up to failure under both wet and dry conditions for both formulations of the bone substitute. Antibiotic release was analysed microbiologically for two antibiotics, vancomycin and gentamicin, over an elution period of 10 days using the agar diffusion method.The drug release analysis resulted in a prolonged release rate of both antibiotics over 10 days. In vitro the amount of gentamicin and vancomycin eluted at day 10. From one pellet still exceeded the minimal inhibitory concentration of most aetiologically important pathogens. Formulation two of the present bone substitute is significantly harder in both wet and dry conditions when compared to formulation one. Both formulations lose strength in the wet condition relative to their performance in the dry condition. However, formulation two is as hard under wet conditions as formulation one is when dry.PerOssal is a suitable new degradable osteoconductive bone substitute that can be loaded with antibiotic solutions, which are released in effective doses over 10 days. The mechanical strength of PerOssal is sufficient to support cancellous bone defects in non-weight-bearing areas or in combination with osteosynthesis. KW - Knochenersatz KW - Leitfähgkeit KW - Antibiotika KW - Biomechanik KW - Bone substitute materials KW - Osteoconductive KW - Osteomyelitis KW - Multiresistant KW - Biomechanics Y1 - 2007 U6 - https://doi.org/10.1007/s00113-007-1229-3 VL - 110 IS - 5 SP - 408 EP - 413 PB - Springer ER - TY - GEN A1 - Saffert, Anne-Sophie A1 - Melzner, Maximilian A1 - Dendorfer, Sebastian T1 - Biomechanical Analysis of the Right Elevated Glenohumeral Joint in Violinists during Legato-Playing T2 - Biomdlore 2021: 21-23 October 2021 Vilnius/Trakai, Lithuania N2 - BACKGROUND: Many statistics reveal that violin players suffer most often from musculoskeletal disorders compared to musicians of other instrument groups. A common phenomenon, especially observed in violin beginners, is the tendency to elevate the right shoulder during playing the violin. This can probably lead to serious disorders in long-term practice with repetitive movements. OBJECTIVE: For this reason, this study investigated the relationship between the right shoulder elevation and the force in the right glenohumeral joint during violin playing. It was hypothesized that the forces in the right glenohumeral joint are higher during playing with the right shoulder raised compared to playing in normal posture. METHODS: Motion capture data from four experienced violinists was recorded and processed by means of musculoskeletal simulation to get the force and elevation angle while playing with raised shoulder and in normal position. RESULTS: The results indicate that the absolute values of the resulting force, as well as the forces in the mediolateral, inferosuperior, and anteroposterior directions, are higher in playing the violin with the shoulder raised than in a normal posture. CONCLUSIONS: Elevating the right shoulder while playing the violin may pose a potential problem. Y1 - 2021 U6 - https://doi.org/10.3233/THC-219001 N1 - Veröffentlicht in: Technology and Health Care, vol. 30, no. 1 (Selected Papers From the 13th International Conference BIOMDLORE 2021), pp. 177-186, 2022 ER - TY - JOUR A1 - Schaeffer, Leon A1 - Herrmann, David A1 - Schratzenstaller, Thomas A1 - Dendorfer, Sebastian A1 - Böhm, Valter T1 - Theoretical considerations on stiffness characteristics of a 3-dimensional tensegrity joint model for the use in dynamic hand orthoses JF - Journal of Medical Robotics Research Y1 - 2025 U6 - https://doi.org/10.1142/S2424905X25400069 PB - World Scientific ER - TY - GEN A1 - Brandt, Hanna A1 - Steinhilber, Bernd A1 - Dendorfer, Sebastian A1 - Pfingsten, Andrea T1 - Exoskelettale Unterstützung in der Pflege - eine Untersuchung der Muskelaktivität, des Hüftflexionswinkels und des subjektiven Belastungsempfinden bei einem simulierten Transfer. T2 - Physioscience N2 - Die dargestellten Ergebnisse weisen darauf hin, dass das in der Studie verwendete passive rückenunterstützende Exoskelett die (wahrgenommene) körperliche Belastung beim dynamischen Transfer eines 45 kg schweren Dummys potenziell reduzieren kann und sich der maximale Hüftgelenksflexionswinkel mit Exo verkleinert. Dieses Ergebnis deckt sich mit bereits publizierten Studienergebnissen von Arbeitsaufgaben im Bereich des Hebens und Tragens von Gegenständen aus der Logistik Y1 - 2025 U6 - https://doi.org/10.1055/s-0045-1808226 VL - 21 IS - S 01 SP - S61 EP - S62 PB - Thieme ER - TY - CHAP A1 - Schaeffer, Leon A1 - Schmaußer, Theresa A1 - Herrmann, David A1 - Lehmann, Lukas A1 - Dendorfer, Sebastian A1 - Böhm, Valter T1 - Multi-Body Simulation of a Dynamic Hand Orthosis based on a Prestressed Compliant Structure Incorporating the Human Hand T2 - 2025 International Symposium on Medical Robotics (ISMR), May 14-16, 2025, Atlanta, GA, USA, N2 - Many dynamic hand orthoses use one degree of freedom joints, such as hinge joints. Therefore, these orthoses can only partially replicate the complex, multi-axis movement of the hand. A possible solution for this is the use of prestressed compliant structures as the basis for orthoses. Determining the joint forces in the wrist and optimizing the dynamic orthosis to influence these forces as well as acting muscle forces are important steps in the development of these orthoses. For this reason, in this work multi-body simulation models of an orthosis with human hand models are presented. Based on these theoretical investigations, more detailed orthosis models as well as initial prototypes of prestressed compliant dynamic hand orthoses can be developed. KW - Hands KW - Wrist KW - Systematics KW - Simulation KW - Dynamics KW - Refining KW - Prototypes KW - Usability KW - Research and development KW - Testing Y1 - 2025 U6 - https://doi.org/10.1109/ISMR67322.2025.11025982 SP - 80 EP - 86 PB - IEEE ER - TY - GEN A1 - Pfingsten, Andrea A1 - Schedel, Valentin A1 - Dendorfer, Sebastian A1 - Gschoßmann, Lukas T1 - Biomechanical characteristics of knee rehabilitation exercises: a new approach for data-based exercise selection N2 - Purpose: The principal objective of our research is to characterize key exercises that represent significant milestones in the rehabilitation process, employing biomechanical parameters to facilitate the distinction between stages of progression. Methods: We conducted an observational cross-sectional study on healthy volunteers (30 years), approved by an ethics committee. Subjects with a history of lower extremity disease were excluded. Movement data was collected, including the following hierarchy of exercise progressions: sit-to-stand-supported (STSS) - sit-to-stand (STS) - squat, stair climbing supported (SCS) - stair climbing (SC) - step-up, single-leg-stance-supported (SLSS) - single-leg-stance (SLS) - single-leg-stance-advanced (SLSA). Motion data was captured using a marker-less system (CapturyLive, v255, TheCaptury, Germany) and used for musculoskeletal simulations in the AnyBody Modeling System (v7.4.4, AnyBodyTechnology, Denmark) with a full-body model. ANOVA or Welch-Test with Bonferroni Post-Hoc was used to describe the anterior-posterior joint reaction force (JRF) normalized for body weight (BW) for each exercise. Positive values indicate an anterior JRF, and negative values a posterior JRF. Results: We recruited 31 subjects (female: 23/74.2%) with a mean age of 22.81 years (SD:2.18). The analysis showed a significant difference in minimum JRF for STSS, STS, and squat (Welch-Test: F(2,56.421)=71.216, p0.001). Post-hoc analysis revealed that posterior JRF for STSS (mean:-2.63BW, SD:0.53) was lower than for STS (mean:-3.74BW, SD:0.42, p0.001), and STS was lower than squat (mean:-4.02BW, SD:0.35, p=0.043). No significant differences were observed in maximum JRF in the posterior direction (ANOVA: F(2,87)=1.151, p=0.324). For single-leg-stance exercises, the minimum JRF was similar for SLSS (mean:-0.34BW, SD:0.22) and SLS (mean:-0.55BW, SD:0.25, p=0.056), but higher in the posterior direction for SLSA (mean:-0.98BW, SD:0.49, p0.001; Welch-Test: F(2,54.379)=22.536, p0.001). Maximum JRF differences were also significant (ANOVA: F(2,87)=11.546, p0.001), with SLSS (mean:0.01BW, SD:0.22) showing a significant higher anterior JRF compared to SLS (mean:-0.16BW, SD:0.19, p=0.020). In the progression from SCS, SC to step-up, there was a significant difference in minimum JRF (ANOVA: F(2,87)=5.33, p=0.007), but not in maximum JRF (ANOVA: F(2,87)=0.624, p=0.538). SCS (mean:-3.42BW, SD:0.38) and SC (mean:-3.48BW, SD:0.54) showed no difference (p=1.000), but SC was significantly higher than step-up (mean:-3.58BW, SD:0.62, p=0.036). Conclusion(s): The exercises show differences in the JRF according to stages of progression, which can be taken into account when selecting exercises. Future research should address the group of patients who have undergone knee arthroplasty. Implications: In the future, it may be feasible to quantify patients' resilience based on sensor data and associate this with the optimal progression of an exercise sequence throughout the rehabilitation process. KW - Physiotherapie KW - Biomechanik KW - Rehabilitation KW - Knie KW - Physiotherapie Y1 - 2025 U6 - https://doi.org/10.82161/v9a4-yt39 ER - TY - JOUR A1 - Barthel, Mareike A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Application of a transformer encoder for the prediction of intra-abdominal pressure JF - Computer Methods in Biomechanics and Biomedical Engineering N2 - Intra-abdominal pressure is a significant physiological parameter influencing spinal stability and pelvic floor health. This study investigates the potential of a transformer encoder model to predict IAP using motion capture data and musculoskeletal modeling. Data from 211 subjects performing walking, fast walking, and running were used to train a transformer encoder. The model showed promising results with an overall Mean Absolute Percentage Error of 13.5% and a Pearson correlation coefficient of 0.85. Predictions for fast walking and running proved to be more challenging compared to walking, which was attributed to the greater variability and complexity of faster movements. KW - Intra-abdominal pressure KW - transformer encoder KW - machine learning KW - motion capture KW - musculoskeletal modeling Y1 - 2025 U6 - https://doi.org/10.1080/10255842.2025.2586143 N1 - Corresponding author der OTH Regensburg: Mareike Barthel PB - Taylor & Francis ER - TY - GEN A1 - Dendorfer, Sebastian T1 - Towards a deeper understanding of Pelvic Floor Disorders via Biomechanical Models Y1 - 2025 ER - TY - GEN A1 - Dendorfer, Sebastian T1 - Zahlen statt Meinung – virtuelle Ganzkörpermodelle für die Mensch-Fahrzeug-Interaktion Y1 - 2025 ER - TY - JOUR A1 - Tröster, Mark A1 - Eckstein, Simon A1 - Kennel, Paula A1 - Kopp, Verna A1 - Benkiser, Alina A1 - Bihlmeier, Felicitas A1 - Daub, Urban A1 - Maufroy, Christophe A1 - Dendorfer, Sebastian A1 - Fritzsche, Lars A1 - Schneider, Urs A1 - Bauernhasl, Thomas T1 - Person-specific evaluation method for occupational exoskeletons - Biomechanical body heat map JF - Applied Ergonomics N2 - Human-centred and ergonomic work design is one of the most important drivers for increasing the competitiveness of the European Union. As a flexible, person-specific occupational measure, exoskeletons promise great potential for effectively reducing individual ergonomic stress. Digital human models can provide important insights and offer great potential for systematising the effect and targeted use of exoskeletons, supporting their effective implementation in practice. In this article, digital human models are applied on two levels. Firstly, a realistic industrial logistics scenario in which boxes had to be relocated is designed with the help of a digital human model for workplace and process planning and secondly, a new biomechanical evaluation methodology to analyse intended and unintended effects on internal stress on the human body is demonstrated by applying musculoskeletal exoskeleton human models of four test subjects. Finally, the modelled biomechanical support tendencies of one exoskeleton are preliminary validated using EMG measurement data of the back muscles collected from the four male workers. The preliminary analysis of two back-support exoskeletons to demonstrate the new methodological approach confirms the expected, intended effects in the lower back and reveals unintended effects, such as e.g. changes in knee kinetics when applying a soft or hard-frame exoskeleton. Furthermore, the exemplary results to demonstrate the methodological approach expose notable differences between the test subjects, which underlines the relevance of person-specific evaluation and consideration of exoskeleton support. The preliminary validation shows a correlation between the modelled and the EMG-measured biomechanical exoskeleton support of the considered back muscles. KW - Industry 5.0 KW - Ergonomics KW - Digital human modelling KW - Biomechanics KW - Musculoskeletal modelling KW - Occupational exoskeletons Y1 - 2025 U6 - https://doi.org/10.1016/j.apergo.2025.104671 VL - 132 PB - Elsevier ER - TY - GEN A1 - Gschoßmann, Lukas A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Impact of Model Parameters on Ground Reaction Force Predictions in Musculoskeletal Modelling T2 - ISB 2025 - The XXX Congress of the International Society of Biomechanics, 27-31 July, Stockholm N2 - This study evaluated how model parameters affect ground reaction force (GRF) predictions in musculoskeletal simulations. A parameter study varying contact height and velocity thresholds and marker weights was conducted. While height and velocity thresholds had minimal impact, marker weights impact prediction errors. These findings highlight the importance of carefully selecting model parameters. Y1 - 2025 ER - TY - GEN A1 - Stein, Leonhard A1 - Schmitz, Paul A1 - Kretschmer, Rainer A1 - Dendorfer, Sebastian T1 - Gait parameter based fall risk scoring N2 - This study explored the connection between subjective self-assessed gait insecurities and objective movement scores. 93 subjects answered detailed fall risk questionnaires and performed functional tests. Significantly different movement patterns between fallers and non-fallers were found. Y1 - 2025 ER - TY - GEN A1 - Förstl, Nikolas A1 - Adler, Ina A1 - Süß, Franz A1 - Jansová, Magdalena A1 - Vychytil, Jan A1 - Dendorfer, Sebastian T1 - Evaluating the loads on the female pelvic floor during full-body activities using computational models N2 - This work investigated the loads on the female pelvic floor during various full-body movements using computational models to calculate abdominal pressure and organ dynamic loads. While high-impact exercises resulted in higher loads, other movements showed lower loads, potentially indicating, which movements may be performed without risking pelvic floor overload and subsequent dysfunctions. Y1 - 2025 ER - TY - GEN A1 - Barthel, Mareike A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Predicting intra-abdominal pressure during walking and running T2 - ISB 2025 - The XXX Congress of the International Society of Biomechanics, 27-31. July 2025, Stockholm N2 - Intra-abdominal pressure (IAP) is an important physiological parameter, which is difficult to measure during physical activity. In this study, motion capture, musculoskeletal modeling and a transformer encoder model are used to predict IAP during walking and running. The model showed promising results with an overall mean percentage error of 13.5% and a Pearson correlation coefficient of 0.85. Minor challenges included the lower accuracy for fast walking and running and the limited amount of data. All in all, the prediction of IAP was successful, which opens up prospects for further applications. KW - Intra-abdominal pressure; machine learning; motion capture; musculoskeletal modeling; transformer encoder Y1 - 2025 ER - TY - GEN A1 - Adler, Ina A1 - Förstl, Nikolas A1 - Čechová, Hana A1 - Nováček, Vít A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Mechanistic analysis of pelvic floor functionality using musculoskeletal simulation T2 - ISB 2025 - The XXX Congress of the International Society of Biomechanics, 27-31 July 2025, Stockholm N2 - There is consensus that knowledge about the fundamentals of the pelvic floor remains incomplete, particularly regarding the sensitivity of individual pelvic floor muscles to posture variations. This study aimed to investigate the effects of variations in pelvic tilt and the point of force application induced by changes in posture on pelvic floor activity using musculoskeletal simulation. A parameter study analysed various loading cases, highlighting the coherent response of individual pelvic floor muscles to loads. Muscle activities and forces were compared across different force application points and pelvic tilt angles. A key finding was identifying peak muscle activity conditions that could help better understand the causes of pelvic floor disorders. Y1 - 2025 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-87294 ER - TY - GEN A1 - Gschoßmann, Lukas A1 - Schedel, Valentin A1 - Süß, Franz A1 - Weber, Markus A1 - Pfingsten, Andrea A1 - Dendorfer, Sebastian T1 - Evaluating Knee Joint Loads Across Exercises and Activities of Daily Living to Personalize TKA Rehabilitation T2 - ISB 2025 - The XXX Congress of the International Society of Biomechanics, 27.-31. July 2025, Stockholm N2 - This study assessed knee joint loading during various physiotherapy exercises and activities of daily living in 30 healthy subjects. Results showed that lunges and squats caused the highest joint forces, while gait and stair activities also imposed substantial loads. These findings support datadriven exercise selection for personalized rehabilitation after total knee arthroplasty. Y1 - 2025 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-87252 ER - TY - JOUR A1 - Kraus, Richard F. A1 - Knipfer, Maximilian L. A1 - Jacob, Matthias A1 - Kieninger, Baerbel A1 - Alikhani, Jasmine A1 - Ghamsary, Parham Heydarzadeh A1 - Reinker, Lukas A1 - Adler, Ina A1 - Dendorfer, Sebastian A1 - Kieninger, Martin T1 - Effectiveness and safety of techniques for cervical spine immobilization in mountain rescue JF - Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine N2 - BACKGROUND Cervical spine injuries in alpine sports require immediate immobilization at the site of the accident to avoid possible secondary damage caused by transportation. Using special sensor technology, this study investigated whether a cervical spine orthosis (cervical collar, Stifneck collar (Laerdal Medical GmbH, Puchheim, Germany)) provides greater stability than a vacuum mattress alone. METHODS Using one male test person, we simulated transporting a patient with a spinal injury in steep alpine terrain. A wireless motion capture system (Xsens Technologies, Movella™ Inc., Henderson, USA) was used to record motion in three-dimensional space within a standardized environment. All tests were performed on a set course by the Bavarian Mountain Rescue Service. The test person lay on a mountain rescue stretcher and was immobilized with a vacuum mattress, either with or without a cervical orthosis. The axes of cervical spine movements were analyzed separately. RESULTS There were no significant differences between immobilization with and without a cervical orthosis with regard to lateral flexion (max. 3.7° compared to 3.0°) in the frontal plane and maximum excursion in flexion (max. 1.6° compared to 2.8°) or extension (max. -1.6° compared to -1.7°). There was significantly greater rotation movement around the craniocaudal axis without an orthosis (max. 2.4° compared to 1.3°). CONCLUSION During mountain rescues, the cervical spine can be immobilized without a rigid cervical spine orthosis. Future research should explore the fundamental benefits of cervical spine immobilization, while the findings of this work contribute to the safe care of patients by avoiding the disadvantages associated with rigid cervical orthoses. KW - Cervical spine KW - Immobilization KW - Mountain rescue KW - Orthosis KW - Vacuum mattress Y1 - 2026 U6 - https://doi.org/10.1186/s13049-025-01530-z VL - 34 PB - Springer ER - TY - JOUR A1 - Kraus, Richard A1 - Knipfer, Maximilian A1 - Jacob, Matthias A1 - Kienninger, Baerbel A1 - Alikhani, Jasmine A1 - Ghamsary, Parham Heydarzadeh A1 - Reinker, Lukas A1 - Adler, Ina A1 - Dendorfer, Sebastian A1 - Kieninger, Martin T1 - Effectiveness and safety of techniques for cervical spine immobilization in mountain rescue JF - Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine N2 - Background Cervical spine injuries in alpine sports require immediate immobilization at the site of the accident to avoid possible secondary damage caused by transportation. Using special sensor technology, this study investigated whether a cervical spine orthosis (cervical collar, Stifneck collar (Laerdal Medical GmbH, Puchheim, Germany)) provides greater stability than a vacuum mattress alone. Methods Using one male test person, we simulated transporting a patient with a spinal injury in steep alpine terrain. A wireless motion capture system (Xsens Technologies, Movella™ Inc., Henderson, USA) was used to record motion in three-dimensional space within a standardized environment. All tests were performed on a set course by the Bavarian Mountain Rescue Service. The test person lay on a mountain rescue stretcher and was immobilized with a vacuum mattress, either with or without a cervical orthosis. The axes of cervical spine movements were analyzed separately. Results There were no significant differences between immobilization with and without a cervical orthosis with regard to lateral flexion (max. 3.7° compared to 3.0°) in the frontal plane and maximum excursion in flexion (max. 1.6° compared to 2.8°) or extension (max. -1.6° compared to -1.7°). There was significantly greater rotation movement around the craniocaudal axis without an orthosis (max. 2.4° compared to 1.3°). Conclusion During mountain rescues, the cervical spine can be immobilized without a rigid cervical spine orthosis. Future research should explore the fundamental benefits of cervical spine immobilization, while the findings of this work contribute to the safe care of patients by avoiding the disadvantages associated with rigid cervical orthoses. KW - Mountain rescue KW - Orthosis KW - Cervical spine KW - Immobilization KW - Vacuum mattress Y1 - 2026 U6 - https://doi.org/10.1186/s13049-025-01530-z VL - 34 PB - Springer ER -