TY - CHAP A1 - Putzer, Michael A1 - Galibarov, Pavel E. A1 - Dendorfer, Sebastian T1 - Influence of vertebral parameters on lumbar spine loading T2 - Pre-meeting SpineFX, Eurospine 2013, Liverpool, UK Y1 - 2013 ER - TY - JOUR A1 - Weber, Tim A1 - Dullien, Silvia A1 - Grifka, Joachim A1 - Renkawitz, Tobias A1 - Dendorfer, Sebastian T1 - Validation of a Motion Capture Laboratory and a new marker-placement protcol for clinical applications JF - Gait & Posture Y1 - 2013 U6 - https://doi.org/10.1016/j.gaitpost.2013.07.229 VL - 38 IS - Suppl. 1 SP - 113 EP - 114 ER - TY - CHAP A1 - Weber, Tim A1 - Dullien, Silvia A1 - Putzer, Michael A1 - Dendorfer, Sebastian A1 - Renkawitz, Tobias T1 - Biomechanical outcome after computer-assisted vs. conventional THR – study concept and preliminary gait analysis results T2 - GAMMA Workshop, Hannover, 2012 Y1 - 2012 ER - TY - CHAP A1 - Weber, Tim A1 - Dendorfer, Sebastian A1 - Renkawitz, Tobias A1 - Dullien, Silvia A1 - Grifka, Joachim T1 - Clinical gait analysis combined with musculoskeletal modelling – coding a new generation of evaluation instruments T2 - Deutsche Gesellschaft für Biomechanik, Murnau, 2011 Y1 - 2011 ER - TY - CHAP A1 - Spreiter, G. A1 - Galibarov, Pavel E. A1 - Dendorfer, Sebastian A1 - Ferguson, Stephen J. T1 - Influence of kyphosis on spinal loading T2 - 10th International Symposium Computer Methods in Biomechanics and Biomedical Engineering (CMBBE) Meeting, 11. - 14. April 2012, Berlin Y1 - 2012 ER - TY - CHAP A1 - Putzer, Michael A1 - Weber, Tim A1 - Dendorfer, Sebastian T1 - Design studies on hip prosthesis using patient specific data T2 - Simpleware Users meeting, November 9th 2011, Bristol, UK Y1 - 2011 ER - TY - CHAP A1 - Dendorfer, Sebastian T1 - The effect of multifidus muscles atrophy following disc herniation on disc loading T2 - Deutsche Gesellschaft für Biomechanik, Murnau, 2011 Y1 - 2011 ER - TY - CHAP A1 - Galibarov, Pavel E. A1 - Al-Munajjed, Amir Andreas A1 - Dendorfer, Sebastian A1 - Christensen, Soeren Toerholm A1 - Rasmussen, John T1 - The effect of varying the stiffness of spinal fusion devices on the adjacent levels using multibody dynamics simulation T2 - Orthopaedic Proceedings N2 - INTRODUCTION Several clinical studies demonstrated long-term adjacent-level effects after implantation of spinal fusion devices[1]. These effects have been reported as adjacent joint degeneration and the development of new symptoms correlating with adjacent segment degeneration[2] and the trend has therefore gone to motion preservation devices; however, these effects have not been understood very well and have not been investigated thoroughly[3]. The aim of this study is to investigate the effect of varying the stiffness of spinal fusion devices on the adjacent vertebral levels. Disc forces, moments and facet joint forces were analyzed. METHODS The AnyBody Modeling System was used to compute the in-vivo muscle and joint reaction forces of a musculoskeletal model. The full body model used in this study consists of 188 muscle fascicles in the lumbar spine and more than 1000 individual muscle branches in total. The model has been proposed by de Zee et al.[3], validated by Rasmussen et al.[4] and by Galibarov et al.[5]. The new model[5] determines the individual motions between vertebrae based on the equilibrium between forces acting on the vertebrae from muscles and joints and the passive stiffness in disks and ligaments, figure 1a. An adult of 1.75 m and 75 kg with a spinal implant in L4L5 was modeled. This model was subjected to a flexion-extension motion using different elastic moduli to analyze and compare to a non-implanted scenario. The analyzed variables were vertebral motion, the disc reaction forces and moments, as well as facet joint forces in the treated and the adjacent levels: L2L3, L3L4, L4L5 and L5-Sacrum. RESULTS When introducing a spinal fusion device in the L4L5 joint the reaction forces and moments decreased in this joint with stiffer devices leading to lower joint loads. However, in the adjacent joints, L3L4 and L5Sacrum, an increase was observed when implanting stiffer devices. Similar trends could be found for the L2L3 joint. The loads in the facet joints showed the same trends. While introducing a spinal fusion device reduced the facet joint forces in the treated joint, the loads in the adjacent facet joints were increased according to the stiffness of the implanted device, figure 1b. DISCUSSION While the treated disc joint showed reduced motion and loads, the adjacent levels demonstrated a significant increase. In particular, the increased facet joint forces in the adjacent levels can lead to adjacent level facet pain or accelerated facet joint degeneration. Introducing a device resulted in preventing facet contact and therefore facet joint loads, even using the device with the lowest stiffness. CONCLUSION The presented model shows that clinical complications such as facet joint degeneration in adjacent levels after implantation of spinal fusion device are consistent with the change in the mechanical-stimulus distribution in the system. Y1 - 2011 VL - 94-B IS - SUPP_XL01 Sep 2012 SP - 2 ER - TY - CHAP A1 - Galibarov, Pavel E. A1 - Dendorfer, Sebastian A1 - Christensen, Soeren Toerholm T1 - On modelling spine curvature dependent on muscular and external forces in multibody dynamics system T2 - International Society of Biomechanics (ISB), 13th congress, 2011, Brussels, Belgium N2 - This paper presents a computational approach for investigating effect of muscular and external forces on curvature of the lumbar spine. Multibody dynamics system is used to compute the lumbar spine curvature using a force-dependent kinematics facility, e.g. this method allows releasing some degrees of freedom in order to be computed based on the current load configuration. Y1 - 2011 UR - https://paperpile.com/shared/63VCBY/download/2608c6d1-adef-0330-86f8-7996e623c627 SP - 2 ER - TY - CHAP A1 - Rasmussen, John A1 - Bichler, R. A1 - Christensen, Soeren Toerholm A1 - Wirix-Speetjens, Roel A1 - Dendorfer, Sebastian A1 - Renkawitz, Tobias T1 - Subject-specific Musculoskeletal Simulation of Hip Dislocation Risk in Activities of Daily Living T2 - Proceedings of the 2011 ORS Annual Meeting, Long Beach, CA. Y1 - 2011 UR - http://www.ors.org/Transactions/57/0306.pdf IS - Paper No. 306 ER - TY - CHAP A1 - Robie, Bruce A1 - Dendorfer, Sebastian A1 - Rasmussen, John A1 - Christensen, Soeren Toerholm T1 - Axial Rotation Requires Greatest Load in Multifidus Muscle – Potential Association with Low Back Pain? T2 - Annual Meeting of the AANS/CNS Section on Disorders of the Spine and Peripheral Nerves, 2011, Phoenix, Arizona Y1 - 2011 UR - https://paperpile.com/shared/o0LQEG ER - TY - CHAP A1 - Dendorfer, Sebastian A1 - Rasmussen, John A1 - Christensen, Soeren Toerholm A1 - Robie, Bruce T1 - The Effect of Spinal Disc Herniation on Multifidus Muscles T2 - 56th Orthopaedic Research Society Meeting, New Orleans, USA, 2010 Y1 - 2010 UR - https://www.ors.org/Transactions/56/1487.pdf ER - TY - CHAP A1 - Galibarov, Pavel E. A1 - Dendorfer, Sebastian A1 - Rasmussen, John T1 - Two Computational Models of the Lumbar Spine: BT - Comparison and Validation T2 - Proceedings of the 2011 ORS Annual Meeting, Long Beach, CA, vol. Marie Curie Initial Training Network "SpineFX" Y1 - 2011 UR - http://www.ors.org/Transactions/57/0786.pdf ER - TY - CHAP A1 - Horner, Marc A1 - Dendorfer, Sebastian A1 - Kiis, Arne A1 - Lawrenchuk, Mike A1 - Verma, Gunjan T1 - A Patient based simulation workflow for orthopedic device design and analysis T2 - SBC Ortho Workshop, June 2011 Y1 - 2011 ER - TY - CHAP A1 - Andersen, Michael Skipper A1 - de Zee, Mark A1 - Dendorfer, Sebastian A1 - MacWilliams, Bruce A1 - Rasmussen, John T1 - Validation of a detailed lower extremity model based on the Klein Horsman data set T2 - Proceedings of the 12th International Symposium on Computer Simulation in Biomechanics (ISB 2009), July 2nd - 4th 2009, Cape Town, South Africa Y1 - 2009 SP - 27 EP - 28 ER - TY - CHAP A1 - Robie, Bruce A1 - Rasmussen, John A1 - Christensen, Soeren Toerholm A1 - Dendorfer, Sebastian T1 - Herniation Induces 55% Increase in Load of Key Stabilizing Muscle – Impact on Herniation Treatment Devices? T2 - Spine Arthoplasty Society Meeting, New Orleans, 2010 Y1 - 2010 ER - TY - CHAP A1 - Dendorfer, Sebastian A1 - Carbes, S. A1 - Rasmussen, John T1 - The influence of muscle forces on biomechanical fracture fixation simulations – from in-vivo forces to tissue strains T2 - World Congress on Medical Physics and Biomedical Engineering, 7 - 12, 2009, Munich Y1 - 2009 ER - TY - CHAP A1 - Dendorfer, Sebastian A1 - Rasmussen, John T1 - The influence of in-vivo muscle forces on the stress distribution in a vertebral body during activities of daily living T2 - Eurospine Warsaw, Poland 2009 Y1 - 2009 ER - TY - CHAP A1 - Dendorfer, Sebastian T1 - How much iron to pump? The determination of muscle forces for activities of daily living T2 - DGU, Berlin, 2008 Y1 - 2008 ER - TY - GEN A1 - Gschoßmann, Lukas A1 - Dendorfer, Sebastian T1 - Personalized Rehabilitation after Total Knee Arthroplasty T2 - 32nd Annual Meeting of the European Orthopaedic Research Society (EORS 2024), 18 - 20 September 2024, Aalborg Y1 - 2024 ER - TY - CHAP A1 - Melzner, Maximilian A1 - Engelhardt, Lucas A1 - Havelkova, Leonard A1 - Simon, Ulrich A1 - Dendorfer, Sebastian T1 - A new musculoskeletal AnyBody detailed hand model validated by electromyography T2 - 16th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (CMBBE) 2019, New York City, USA N2 - The AnyBody™ Modeling System (AMS) [1], is an universally used musculoskeletal simulation software using inverse dynamics. Until now, no complete human hand model is known in the AMS. Also considering other musculoskeletal software platforms, just one detailed entire hand model is recently published [2] but is only based on one subject. The aim of this work is to implement a full detailed hand model for the AMS including all extrinsic and intrinsic muscles using data by the UWB gained through an anatomical study of ten cadaver hands. Y1 - 2019 UR - https://www.researchgate.net/publication/336944957_A_NEW_MUSCULOSKELETAL_ANYBODY_DETAILED_HAND_MODEL_VALIDATED_BY_ELECTROMYOGRAPHY ER - TY - GEN A1 - Auer, Simon A1 - Krutsch, Werner A1 - Renkawitz, Tobias A1 - Kubowitsch, Simone A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Effect of mental demand on leg loading in highly dynamic motion T2 - AnyBody online Webinar, Oct 2020 N2 - Football players have a high risk of leg muscle injuries, especially when exposed to mental stress. Injuries to muscles of the thigh are common in amateur and professional football, representing almost a third of all injuries. These injuries occur primarily in non-contact situations and from overuse. They can lead to a range of costs, including financial costs associated with treatment as well as those associated with long-term recovery, and absence from training and/or competition. Further, there is a high risk of injury recurrence and subsequent injury. Y1 - 2020 ER - TY - CHAP A1 - Süß, Franz A1 - Kubowitsch, Simone A1 - Rasmussen, John A1 - Verkerke, Gijsbertus Jacob A1 - Dendorfer, Sebastian T1 - The influence of cognitive stress on muscle activation and spinal disc load T2 - European Society of Biomechanics meeting 2019, Vienna, Austria Y1 - 2019 UR - https://owncloud.tuwien.ac.at/index.php/s/dovqqcj02VeZHze ER - TY - GEN A1 - Aurbach, Maximilian A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - The impact of the hill type muscle model on the glenohumeral joint reaction force T2 - 16th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (CMBBE) 2019, New York City, USA Y1 - 2019 ER - TY - CHAP A1 - Aurbach, Maximilian A1 - Wagner, Kilian A1 - Süß, Franz A1 - Dendorfer, Sebastian ED - Badnjevic, Almir T1 - Implementation and Validation of Human Kinematics Measured Using IMUs for Musculoskeletal Simulations by the Evaluation of Joint Reaction Forces T2 - CMBEBIH 2017, Proceedings of the International Conference on Medical and Biological Engineering 2017, Sarajevo, Bosnia and Herzegovina N2 - The gold standard for the analysis of human kinematics and kinetics is a camera-based motion capture system in combination with force measurement platforms. Alternatively, inertial measurement units can be utilized to obtain human kinematics, while ground reaction forces are computed from full body dynamics. This setup represents a system independent from the spatial confinement of a gait laboratory. The aim of this study is the comparison of the two methods by the investigation of lower limb kinematics and the resulting joint reaction forces within the ankle-, knee- and hip joints. For this purpose, human motion during gait was captured simultaneously by both measurement techniques. 13 trials from 8 different test subjects were evaluated in total. IMU data was processed with a quaternion based Kalman Filter. The data sets were implemented into a musculoskeletal simulation program in order to drive a virtual human body model. Each sensor was aligned to the gravitational and magnetic field vectors of the earth. The angles of flexions, extensions and rotations were analyzed to determine kinematic differences. Joint reaction forces defined kinetic dissimilarities. The overall kinematic differences of both models yielded root mean square errors of 7.62°, 6.02°, 4.95°, 2.79°, 2.38° and 3.56° for ankle flexion, subtalar eversion, knee flexion, hip external rotation, hip abduction and hip flexion, respectively. The proximo-distal differences in force peaks between the models yielded overall for the ankle, 57.33 %Bodyweight(BW) ± 46.86 %BW (16.66 %(Maximum peak to peak) ± 13.62 %) for the knee 37.09 %BW ± 29.33 %BW (17.65 % ± 15.44 %) and 32.03 %BW ± 24.33 %BW (15.6 % ± 12.54 %) for the hip. The overall outcome of this work investigated an approach independent of the common setup of the gait laboratory, thus enabling a cheaper and more flexible technology as an alternative. However, kinematic and thus kinetic differences remain rather large. Future work aims to improve the contact criterion for the calculation of the ground reaction forces and the implementation of a full-body calibration algorithm for the IMU system in order to counteract magnetic field disturbances. KW - Inertial Measurement Units KW - Multibody Simulation KW - Musculoskeletal Simulation KW - AnyBody KW - Motion Capture KW - Bewegungsapparat KW - Biomechanik KW - Motion Capturing KW - Mehrkörpersimulation KW - Ground Reaction Force Prediction KW - Gait KW - IMU KW - Joint Reaction Forces Y1 - 2017 U6 - https://doi.org/10.1007/978-981-10-4166-2_31 VL - Vol. 62 SP - 205 EP - 211 PB - Springer CY - Singapore ER - TY - CHAP A1 - Hammer, Joachim A1 - Dendorfer, Sebastian T1 - Cyclic loading and microstructure of cancellous bone T2 - Journal of Biomechanics Y1 - 2008 U6 - https://doi.org/10.1016/S0021-9290(08)70409-3 VL - 41 IS - Suppl. 1, July 2008 SP - S410 ER - TY - CHAP A1 - Dendorfer, Sebastian T1 - Biomechanical evaluation and optimisation of countermeasure exercises T2 - ESA/ESTEC Bedrest Strategy Workshop, Noordwijk, NL, 2009 Y1 - 2009 ER - TY - GEN A1 - Adler, Ina A1 - Förstl, Nikolas A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Biomechanical exposition of the factors influencing the pelvic floor muscle activity T2 - ESB 2024, 29th Congress of the European Society of Biomechanics, 30 June-3 July 2024, Edinburgh, Scotland N2 - Introduction About 40 % of the women worldwide suffer from Pelvic Floor Dysfunctions [1]. In previous studies, musculoskeletal simulations helped to understand and facilitate the complex issues of musculoskeletal disorders in several different branches [2, 3]. A fundamental prerequisite for the generation of these models is to have a basic understanding of the stresses acting on the pelvic floor. The aim of this study is to investigate the biomechanical factors influencing the activity of the pelvic floor muscles by establishing a parameterised model. Methods To identify the factors that affect the pelvic floor muscles, the process is divided into several stages. The first step is to investigate the loads acting on the pelvic floor. For this, a simplified sagittal cross-sectional model of the upper body is analysed. The discretization of the abdominal cavity is presented with resulting force vectors representing the organs in the abdominal and pelvic region, the tensile force of the structures that fixate the organs as well as the intraabdominal pressure. A second step is the examination of the basic mechanics of the pelvic floor muscles. As the functional anatomy of these muscles demonstrate differences compared to other muscle groups [4], the understanding of how they differ is crucial for the construction of musculoskeletal models. After a static examination of loads on a simplified muscle model, an extended model including the physiological properties of a muscle must be involved in the considerations. Therefore, the influence of parameters such as the ideal muscle strength and fibre length, as well as elasticity or passive stiffness of the elements must be taken into account. The influencing factors of the variables can be analysed in a simplified pelvic floor muscle model by systematically changing the parameters. Results The process of analysing the factors influencing the activity of the pelvic floor muscles follows two main strategies. The review of the effects of the whole body identifies the forces acting on the pelvic floor muscles and effect their activity. With the examination of the basic mechanics of a simplified pelvic floor muscle model a better understanding is achieved of how the pelvic floor muscles absorb the loads acting in the body. Discussion This process results in the main influence factors on the activity of the pelvic floor. The consequent parameters form the basis for a biomechanically justified construction of musculoskeletal simulation models of the pelvic floor. Nevertheless, it must be considered, that these mechanical studies represent simplifications of the reality. References 1. Wang et al, Front Public Health, 10:975829, 2022. 2. Bulat et al., Curr Sports Med Rep, 18(6):210-216, 2019 3. Melzner et al., Eur J Obstet Gynecol Reprod Biol, 264:306-313, 2021 4. Ashton-Miller et al., Ann N Y Acad Sci, 1101:266-96, 2007 Y1 - 2024 ER - TY - VIDEO A1 - Auer, Simon A1 - Reinker, Lukas A1 - Süß, Franz A1 - Kubowitsch, Simone A1 - Krutsch, Werner A1 - Weber, Markus A1 - Renkawitz, Tobias A1 - Dendorfer, Sebastian T1 - Webcast: Effect of mental demand on leg loading in highly dynamic motion N2 - Football players have a high risk of leg muscle injuries, especially when exposed to mental stress. Injuries to muscles of the thigh are common in amateur and professional football, representing almost a third of all injuries. These injuries occur primarily in non-contact situations and from overuse. They can lead to a range of costs, including financial costs associated with treatment as well as those associated with long-term recovery, and absence from training and/or competition. Further, there is a high risk of injury recurrence and subsequent injury. KW - Webcast KW - AnyBody KW - Stress KW - Football KW - Speedcourt Y1 - 2020 UR - https://www.youtube.com/watch?v=uSc_9XlnkaA ER - TY - JOUR A1 - Visscher, Rosa A1 - Wyss, C. A1 - Singh, Navrag B. A1 - Taylor, William R. A1 - Dendorfer, Sebastian A1 - Rutz, E. A1 - Brunner, Reinald T1 - Influence of TAL-TATS surgery on energy production of Tricepts Surae - A musculoskeletal modeling evaluation JF - Gait & Posture Y1 - 2020 U6 - https://doi.org/10.1016/j.gaitpost.2020.08.090 VL - 81 IS - Suppl. 1 SP - 381 EP - 382 PB - Elsevier ER - TY - GEN A1 - Gschoßmann, Lukas A1 - Stein, Leonhard A1 - Dendorfer, Sebastian T1 - Subject Specific Scaling Of Muscle Strengths In The Lower Extremity For Musculoskeletal Models T2 - ESB 2024, 29th Congress of the European Society of Biomechanics, 30 June-3 July 2024, Edinburgh, Scotland Y1 - 2024 ER - TY - CHAP A1 - Suess, Franz A1 - Melzner, Maximilian A1 - Dendorfer, Sebastian T1 - Towards ergonomics working - machine learning algorithms and musculoskeletal modeling T2 - IOP Conference Series: Materials Science and Engineering N2 - Ergonomic workplaces lead to fewer work-related musculoskeletal disorders and thus fewer sick days. There are various guidelines to help avoid harmful situations. However, these recommendations are often rather crude and often neglect the complex interaction of biomechanical loading and psychological stress. This study investigates whether machine learning algorithms can be used to predict mechanical and stress-related muscle activity for a standardized motion. For this purpose, experimental data were collected for trunk movement with and without additional psychological stress. Two different algorithms (XGBoost and TensorFlow) were used to model the experimental data. XGBoost in particular predicted the results very well. By combining it with musculoskeletal models, the method shown here can be used for workplace analysis but also for the development of real-time feedback systems in real workplace environments. Y1 - 2021 U6 - https://doi.org/10.1088/1757-899X/1208/1/012001 SN - 1757-899X N1 - Corresponding author: Sebastian Dendorfer VL - 1208 PB - IOP Publishing ER - TY - CHAP A1 - Aurbach, Maximilian A1 - Jungtäubl, Dominik A1 - Spicka, Jan A1 - Dendorfer, Sebastian T1 - EMG-based validation of musculoskeletal models considering crosstalk T2 - World Congress Biomechanics, 28-30 June 2018, Dublin N2 - BACKGROUND: Validation and verification of multibody musculoskeletal models sEMG is a difficult process because of the reliability of sEMG data and the complex relationship of muscle force and sEMG. OBJECTIVE: This work aims at comparing experimentally recorded and simulated muscle activities considering a numerical model for crosstalk. METHODS: For providing an experimentally derived reference data set, subjects were performing elevations of the arm, where the activities of the contemplated muscle groups were measured by sEMG sensors. Computed muscle activities were further processed and transformed into an artificial electromyographical signal, which includes a numerical crosstalk model. In order to determine whether the crosstalk model provides a better agreement with the measured muscle activities, the Pearson correlation coefficient has been computed as a qualitative way of assessing the curve progression of the data sets. RESULTS: The results show an improvement in the correlation coefficient between the experimental data and the simulated muscle activities when taking crosstalk into account. CONCLUSIONS: Although the correlation coefficient increased when the crosstalk model was utilized, it is questionable if the discretization of both, the crosstalk and the musculoskeletal model, is accurate enough. Y1 - 2018 U6 - https://doi.org/10.1109/BIOMDLORE.2018.8467211 ER - TY - GEN A1 - Suess, Franz A1 - Melzner, Maximilian A1 - Dendorfer, Sebastian T1 - Towards Ergonomic working - machine learning algorithms and musculoskeletal modeling T2 - RIM 2021, 13th International Scientific Conference on Manufacturing Engineering, 29 Sept. - 1 Oct 2021, Sarajevo, Bosnia and Herzegovina Y1 - 2021 ER - TY - CHAP A1 - Dendorfer, Sebastian A1 - Englert, Carsten T1 - Forces on a clavicles midshaft fracture and influence of fracture type T2 - AO Symposium, Regensburg, 2009 Y1 - 2009 ER - TY - JOUR A1 - Förstl, Nikolas A1 - Süß, Franz A1 - Englert, Carsten A1 - Dendorfer, Sebastian T1 - Design of a reverse shoulder implant to measure shoulder stiffness during implant component positioning JF - Medical Engineering & Physics N2 - To avoid dislocation of the shoulder joint after reverse total shoulder arthroplasty, it is important to achieve sufficient shoulder stability when placing the implant components during surgery. One parameter for assessing shoulder stability can be shoulder stiffness. The aim of this research was to develop a temporary reverse shoulder implant prototype that would allow intraoperative measurement of shoulder stiffness while varying the position of the implant components. Joint angle and torque measurement techniques were developed to determine shoulder stiffness. Hall sensors were used to measure the joint angles by converting the magnetic flux densities into angles. The accuracy of the joint angle measurements was tested using a test bench. Torques were determined by using thin-film pressure sensors. Various mechanical mechanisms for variable positioning of the implant components were integrated into the prototype. The results of the joint angle measurements showed measurement errors of less than 5° in a deflection range of ±15° adduction/abduction combined with ±45° flexion/extension. The proposed design provides a first approach for intra-operative assessment of shoulder stiffness. The findings can be used as a technological basis for further developments. Y1 - 2023 U6 - https://doi.org/10.1016/j.medengphy.2023.104059 N1 - Corresponding author: Sebstian Dendorfer VL - 121 PB - Elsevier ET - Journal Pre-proof ER - TY - CHAP A1 - Muehling, M. A1 - Englert, Carsten A1 - Dendorfer, Sebastian T1 - Influence of biceps tenotomy and tenodesis on post-operative shoulder strength T2 - Jahrestagung der Deutschen Gesellschaft für Biomechanik, March 2017, Hannover, Germany Y1 - 2017 ER - TY - JOUR A1 - Pfeifer, Christian A1 - Müller, Michael A1 - Prantl, Lukas A1 - Berner, Arne A1 - Dendorfer, Sebastian A1 - Englert, Carsten T1 - Cartilage labelling for mechanical testing in T-peel configuration JF - International Orthopaedics N2 - PURPOSE: The purpose of this study was to find a suitable method of labelling cartilage samples for the measurement of distraction distances in biomechanical testing. METHODS: Samples of bovine cartilage were labelled using five different methods: hydroquinone and silver nitrate (AgNO3), potassium permanganate (KMnO4) with sodium thiosulphate (Na2S2O3), India ink, heat, and laser energy. After the labelling, we analysed the cartilage samples with regard to cytotoxity by histochemical staining with ethidiumbromide homodimer (EthD-1) and calcein AM. Furthermore, we tested cartilages labelled with India ink and heat in a T-peel test configuration to analyse possible changes in the mechanical behaviour between marked and unlabelled samples. RESULTS: Only the labelling methods with Indian ink or a heated needle showed acceptable results in the cytotoxity test with regard to labelling persistence, accuracy, and the influence on consistency and viability of the chondrocytes. In the biomechanical T-peel configuration, heat-labelled samples collapsed significantly earlier than unlabelled samples. CONCLUSION: Labelling bovine cartilage samples with Indian ink in biomechanical testing is a reliable, accurate, inexpensive, and easy-to-perform method. This labelling method influenced neither the biomechanical behaviour nor the viability of the tissue compared to untreated bovine cartilage. KW - Bovine cartilage KW - Cartilage samples KW - Indian ink KW - T-peel configuration KW - Method labeling KW - Knorpel KW - Rind KW - Kennzeichnung KW - Tinte KW - Biomechanik KW - Prüfung Y1 - 2012 U6 - https://doi.org/10.1007/s00264-011-1468-3 VL - 36 IS - 7 SP - 1493 EP - 1499 PB - Springer ER - TY - JOUR A1 - Förstl, Nikolas A1 - Adler, Ina A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Technologies for Evaluation of Pelvic Floor Functionality: A Systematic Review JF - Sensors N2 - Pelvic floor dysfunction is a common problem in women and has a negative impact on their quality of life. The aim of this review was to provide a general overview of the current state of technology used to assess pelvic floor functionality. It also provides literature research of the physiological and anatomical factors that correlate with pelvic floor health. This systematic review was conducted according to the PRISMA guidelines. The PubMed, ScienceDirect, Cochrane Library, and IEEE databases were searched for publications on sensor technology for the assessment of pelvic floor functionality. Anatomical and physiological parameters were identified through a manual search. In the systematic review, 114 publications were included. Twelve different sensor technologies were identified. Information on the obtained parameters, sensor position, test activities, and subject characteristics was prepared in tabular form from each publication. A total of 16 anatomical and physiological parameters influencing pelvic floor health were identified in 17 published studies and ranked for their statistical significance. Taken together, this review could serve as a basis for the development of novel sensors which could allow for quantifiable prevention and diagnosis, as well as particularized documentation of rehabilitation processes related to pelvic floor dysfunctions. Y1 - 2024 U6 - https://doi.org/10.3390/s24124001 N1 - Die Preprint-Version ist ebenfalls in diesem Repositorium verzeichnet unter: https://opus4.kobv.de/opus4-oth-regensburg/frontdoor/index/index/docId/7306 VL - 24 IS - 12 PB - MDPI ER - TY - GEN A1 - Förstl, Nikolas A1 - Adler, Ina A1 - Suess, Franz A1 - Čechová, Hana A1 - Jansová, Magdalena A1 - Cimrman, Robert A1 - Vychytil, Jan A1 - Dendorfer, Sebastian T1 - Workflow for the development of a non-invasive feedback device to assess pelvic floor contractions T2 - ESB 2024, 29th Congress of the European Society of Biomechanics, 30 June-3 July 2024, Edinburgh, Scotland N2 - Introduction Pelvic floor disorders affect about 40% of women worldwide [1]. Pelvic floor muscle (PFM) training is both a preventive and a therapeutic intervention. Current PFM training devices are invasive and have little scientific evidence. The idea is to develop a noninvasive feedback device to assess adequate PFM contraction. Therefore, evidence-based female musculoskeletal models, non-invasive data acquisition, sensor technology and artificial intelligence (AI) will be combined. This work presents the workflow to achieve such a feedback device and describes the interaction of the technologies used. Methods Exercises that induce PFM contractions have been evaluated and defined. Motion capture of these exercises will provide input for female musculoskeletal models. A combination of biomechanical rigid body and FEM simulations will be used to estimate PFM contractions. In addition, a non-invasive sensor will measure pelvic floor activity. The simulated and measured data will be used to develop an AI model that provides feedback on PFM contractions based on non-invasive data collection. Results The AMMR (AnyBody Managed Model Repository) of the AnyBody modelling system (AMS, Aalborg, Denmark) serves as the initial model for performing inverse dynamic simulations of the exercises. To calculate the PFM forces, the full-body model must be supplemented with the relevant pelvic floor structures and a mass model of the internal organs. A modified abdominal pressure model must also be incorporated. The AMS calculates the PFM activities caused by the internal organ loads and the generated abdominal pressure during the exercises. The muscle activities are transferred to a FEM model of the female pelvic floor (SfePy, simple finite elements in Python). The identical pelvic floor structures were integrated into the FEM model as in the AMS. Active PFM contractions can be simulated using the FEM model. Movement of the coccyx due to PFM contractions has been reported in the literature [2,3]. Therefore, a noninvasive coccyx motion sensor will be developed to provide additional information on PFM contractions. The measured data (coccyx motion sensor, motion capture) and the simulation results of the models will be combined to create an AI feedback model using Python. The final feedback device will consist of the AI model and the developed coccyx motion sensor, which can reproduce the resulting PFM contractions based on the sensor data and simplified motion tracking. Discussion The creation of the AMS and the FEM model is a prerequisite for the development of the feedback device. The relevant structures in the models are located inside the body. This limits the ability to observe the structures during the exercises, which can lead to difficulties in model validation. The development of a user-friendly sensor with sufficient measuring accuracy of the coccyx motion is another challenge. Nevertheless, the workflow represents a promising approach to develop a noninvasive feedback system to assess PFM contraction. References 1. Wang et al, Front Public Health, 10:975829, 2022. 2. Bø et al, Neurourol Urodyn, 20:167–174, 2001. 3. Fujisaki et al, J Phys Ther Sci, 30:544–548, 2018. Acknowledgements This work was supported by the project no. BYCZ01-014 of the Program INTERREG Bavaria – Czechia 2021–2027. Y1 - 2024 ER - TY - GEN A1 - Förstl, Nikolas A1 - Süß, Franz A1 - Englert, Carsten A1 - Dendorfer, Sebastian T1 - Design of a reverse shoulder implant to measure shoulder stiffness during implant component positioning T2 - Book of abstracts / ESB 2023, 28th Congress of the European Society of Biomechanics, 9-12 July 2023, Maastricht, The Netherlands. N2 - Introduction Dislocation of the shoulder joint is one of the more common complications after reverse total shoulder arthroplasty [1], which is often associated with malposition of the prosthetic components [2]. Therefore, achieving sufficient shoulder stability should not be neglected when positioning the implant components. One parameter for assessing shoulder stability can be shoulder stiffness. The aim of this work is to develop a reverse shoulder implant prototype that allows intraoperative measurement of shoulder stiffness while varying the position of the implant components. The measured stiffness could provide a quantitative statement regarding the optimal positioning of the implant components, which can be adjusted accordingly in the final reverse shoulder prosthesis. Methods To measure the stiffness of the shoulder joint, it is necessary to record the joint angles and the torques generated during movement. The changes in the rotation angles were measured using 3D hall sensors and magnets. The magnets were placed under the humerosocket, and the hall sensors were integrated into the glenosphere. The strength of the magnetic field was used to determine the position of the humerosocket in relation to the glenosphere. The accuracies of the angle measurements were tested using a test bench. Three thin film pressure sensors were used to record forces at different points under the humerosocket. To obtain a force value from the sensor signal, the sensors were calibrated using a load cell. The variation of the implant components positions was integrated into the prototype implant through different constructive mechanisms to adjust the stiffness of the shoulder joint. Results In the range of ±45° flexion/extension combined with ±15° adduction/abduction, the joint position could be determined with sufficient accuracy (error e ≤ 5°). The areas near the combined maximum deflections of ±45° flexion/extension and ±45° adduction/abduction indicate the greatest deviation from the target angle. The force values of the thin film sensors enable the calculation of moments around two axes. As variable component position parameters, the tray offset, the neck-shaft angle and the humerus version were integrated into the implant prototype. Discussion Ideally, the accuracy of the angle measurements should only depend on the amount of deflection and not on the direction of deflection. The asymmetric behavior indicates a deviation from the correct positioning of the hall sensors. The application of a calibration matrix could compensate for the measurement errors and could demonstrate the potential of the new method for joint angle measurements. The accuracy of the torque measurements and the functionality of the mechanical arresting mechanisms must be investigated in further studies. Overall, the developed measurement method can help to avoid malpositioning of the implant components in reverse total shoulder arthroplasty. References 1. Clark et al, J Shoulder and elbow surgery, 21:36-41 2012. 2. Randelli et al, J Musculoskeletal surgery, 98:15-18, 2014. Y1 - 2023 UR - https://esbiomech.org/conference/archive/2023maastricht/332.pdf ER - TY - GEN A1 - Melzner, Maximilian A1 - Ismail, Khaled M. A1 - Rušavý, Zdeněk A1 - Kališ, Vladimír A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Musculoskeletal Lower Back Load of Accoucheurs During Delivery T2 - 26th Congress of the European Society of Biomechanics, July 11-14, 2021, Milan, Italy N2 - With the progress in modern medicine, it was possible to significantly reduce the risks of birth for mother and child. One aspect that has received less attention so far is the risk of injury to the accoucheurs (obstetricians and midwives) during the birth process. Indeed, studies indicate that 92% of midwives suffer from musculoskeletal disorders, with the lower back being the main cause of complaints (72%). The aim of this study was to investigate two commonly used postural techniques used by accoucheurs during childbirth and to analyze the resulting load on the lower back using the AnyBodyTM musculoskeletal simulation software. Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-20208 CY - Milan ER - TY - JOUR A1 - Melzner, Maximilian A1 - Ismail, Khaled M. A1 - Rušavy, Zdenek A1 - Kališ, Vladimír A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Musculoskeletal lower back load of accoucheurs during childbirth – A pilot and feasibility study JF - European Journal of Obstetrics & Gynecology and Reproductive Biology N2 - Introduction: Back problems represent one of the leading causes of accouchers' work-related musculoskeletal morbidities. The correct execution of birth-related maneuvers including manual perineal protection is crucial not only for the mother and child but also for obstetricians and midwives to reduce any strain on their musculoskeletal system. Therefore, the overall aim of this study was to test the feasibility of determining the effect of different accouchers' postures (standing and kneeling) on their musculoskeletal system. Methods: The biomechanical analysis is based on musculoskeletal simulations that included motion recordings of real deliveries as well as deliveries conducted on a birthing simulator. These simulations were then used to determine individual joints' loads. Results: In the kneeling posture, both a low intra-operator variability and a lower average maximum load of the lower back was observed. For the standing position the spine load was reduced by pivoting the elbow on the accouchers' thigh, which in turn was associated with a significantly greater load on the shoulder joint. Conclusion: The study demonstrated the feasibility of our technique to assess joints loads. It also provided initial data indicating that a posture that reduces spinal flexion and tilt, achieved in this study by the kneeling, can significantly reduce the strain on the practitioner's musculoskeletal system. KW - lower back load KW - Accoucheur KW - Musculoskeletal simulation Y1 - 2021 U6 - https://doi.org/10.1016/j.ejogrb.2021.07.042 IS - 264 SP - 306 EP - 313 PB - Elsevier ER - TY - JOUR A1 - Rusavy, Zdenek A1 - Cechova, Hana A1 - Dendorfer, Sebastian A1 - Kalis, Vladimir A1 - Ismail, Khaled M. T1 - Is the Finnish grip tight enough? A manometric study of two manual perineal protection techniques JF - Acta Obstetricia et Gynecologica Scandinavica Y1 - 2025 U6 - https://doi.org/10.1111/aogs.15033 VL - 104 IS - 2 SP - 423 EP - 425 PB - Wiley ER - TY - JOUR A1 - Morag, Sarah A1 - Kieninger, Martin A1 - Eissnert, Christoph A1 - Auer, Simon A1 - Dendorfer, Sebastian A1 - Popp, Daniel A1 - Hoffmann, Johannes A1 - Kieninger, Bärbel T1 - Comparison of different techniques for prehospital cervical spine immobilization: Biomechanical measurements with a wireless motion capture system JF - PLOS ONE Y1 - 2023 U6 - https://doi.org/10.1371/journal.pone.0292300 VL - 18 IS - 11 SP - 1 EP - 14 PB - PLOS CY - San Francisco, California ER - TY - JOUR A1 - Hoenicka, Markus A1 - Lehle, Karla A1 - Jacobs, V. R. A1 - Dendorfer, Sebastian A1 - Kostorz, A. A1 - Schmid, F. X. A1 - Birnbaum, D. E. T1 - Mechanical and seeding properties of human umbilical vein – a potential scaffold for a tissue-engineered vessel graft JF - The Thoracic and Cardiovascular Surgeon N2 - Objectives: The mechanical properties and seeding with endothelial cells were investigated in fresh and cryopreserved human umbilical vein. Methods: Human umbilical veins (HUV) were frozen in Euro-Collins/1M DMSO at –1°C/min and stored in liquid nitrogen. Stress-strain relationships of fresh and thawed veins were determined in an uniaxial tension-testing rig. HUV endothelial cells (HUVEC) were seeded onto denuded HUV under static conditions and grown for 3d. Luminal surfaces were analyzed by scanning electron microscopy. Calcein-stained cells were seeded hyperconfluently to determine the cell retention capacity of fresh and cryopreserved veins. Results: The stress-strain relationships of HUV followed a biphasic pattern typical for natural vessels. Neither the failure stress (2.71±0.36 vs. 3.25±0.97 N, n=3) nor the displacement required to achieve failure (9.73±0.9 vs. 7.43±2.07mm, n=3) were altered by cryopreservation. The burst pressure was estimated as approx. 1000mm Hg within the limitations of the uniaxial model. HUVEC seeded onto denuded HUV formed patches (at 9E3 cells per cm2) or an almost confluent endothelium (at 3E4 cells per cm2) within three days. The capacity to retain seeded HUVEC of denuded HUV was not altered by cryopreservation (1.15±0.08E5 vs. 1.26±0.14E5 cells per cm2, n=6). Conclusions: The burst pressure of HUV seems to be sufficiently high for the human arterial circulation and is not altered by cryopreservation. HUVEC can establish a confluent endothelium on denuded HUV. Therefore HUV appears to be a suitable storable scaffold for vascular tissue engineering. KW - Nabelvene KW - Tissue Engineering Y1 - 2007 U6 - https://doi.org/10.1055/s-2007-967592 VL - 55 IS - S 1 SP - P_37 PB - Thieme ER - TY - JOUR A1 - Lazarev, Igor A. A1 - Riabokon, P. V. A1 - Haller, M. A1 - Dendorfer, Sebastian T1 - Effect of the Displacement of Calcaneal Bone Peripheral Fragment in its Fracture on the Function of the Three-Headed Calf Muscle JF - TRAUMA N2 - In the structure of musculoskeletal injuries, calcaneal fractures account for up to 4 % of all skeletal fractures and up to 60 % of hindfoot fractures. The effect of the displacement of the peripheral fragment of the calcaneus on the calf muscles’s reaction forces at the time of the adoption of the simplified squatting position was investigated by modeling in AnyBody Modeling System 6.0 software. M.gastrocnemius (lateralis et medialis) in the initial phase of motion in all variants of the peripheral fragment displacement did not develop sufficient muscular effort in comparison to the intact calcaneus. M.soleus medialis et lateralis showed significant increase in muscle activity rates in the initial phase of motion (41.87 ± 1.90 H and 52.07 ± 2.10 H) before reaching its maximum values, as compared with those of the intact calcaneus. In the final phase of the movement, upon muscle reaches its maximum length, muscular strength indicators of the m.soleus returned to their original values or were significantly below them. The decline in muscle strength was due to shortening of the moment arm or muscle excursion in case of convergence of muscle attachment points. When the peripheral fragment is displaced, due to putting down the heel to the surface of the support in terms of anatomical muscle lengthening, it takes extra effort to achieve rest length and its maximum power. In all types of the displacement of the peripheral fragment, the function of three-headed calf muscle is disturbed with involvement of additional muscular effort and energy expenditure. This fact should motivate the surgeon on the need for accurate repositioning of bone fragments in calcaneal fractures with the displacement of the peripheral fragment. Y1 - 2016 U6 - https://doi.org/10.22141/1608-1706.2.16.2015.80247 VL - 16 IS - 2 SP - 20 EP - 24 PB - Zaslavsky ER - TY - JOUR A1 - Lazarev, Igor A. A1 - Ryabokon, P.V. A1 - Haller, M. A1 - Dendorfer, Sebastian T1 - Effect of the fractured calcaneus's peripheral fragment displacement on the triceps surae function JF - ЖУРНАЛ «ТРАВМА» Ukrainian Trauma Journal Y1 - 2015 VL - 2, TOM 16 ER - TY - JOUR A1 - Dendorfer, Sebastian A1 - Maier, Hans Jürgen A1 - Hammer, Joachim T1 - Fatigue damage in cancellous bone: an experimental approach from continuum to micro scale JF - Journal of the Mechanical Behavior of Biomedical Materials N2 - Repeated loadings may cause fatigue fractures in bony structures. Even if these failure types are known, data for trabecular bone exposed to cyclic loading are still insufficient as the majority of fatigue analyses on bone concentrate on cortical structures. Despite its highly anisotropic and inhomogeneous structure, trabecular bone is treated with continuum approaches in fatigue analyses. The underlying deformation and damage mechanism within trabecular specimens are not yet sufficiently investigated. In the present study different types of trabecular bone were loaded in monotonic and cyclic compression. In addition to the measurement of integral specimen deformations, optical deformation analysis was employed in order to obtain strain distributions at different scale levels, from the specimens' surface to the trabeculae level. These measurements allowed for the possibility of linking the macroscopic and microscopic mechanical behaviour of cancellous bone. Deformations were found to be highly inhomogeneous across the specimen. Furthermore strains were found to already localise at very low load levels and after few load cycles. Microcracks in individual trabeculae were induced in the very early stage of cyclic testing. The results provide evidence of the capability of the method to supply essential data on the failure behaviour of individual trabeculae in future studies. KW - Knochen KW - Spongiosa KW - Ermüdungsbruch KW - Fatigue KW - Cancellous bone KW - Deformation behaviour KW - Damage KW - Measurement and testing KW - Mechanical behaviour Y1 - 2009 U6 - https://doi.org/10.1016/j.jmbbm.2008.03.003 VL - 2 IS - 1 SP - 113 EP - 119 ER - TY - CHAP A1 - Dendorfer, Sebastian A1 - Maier, Hans Jürgen A1 - Hammer, Joachim T1 - How do age and anisotropy affect the fatigue behaviour of cancellous bone? T2 - Medicine Meets Engineering N2 - The fatigue behaviour of materials is of particular interest for the failure prediction of materials and structures exposed to cyclic loading. For trabecular bone structures only a few sets of lifetime data have been reported in the literature and structural measures are commonly not considered. The influence of load contributions not aligned with the main physiological axis remains unclear. Furthermore age effects on the fatigue behaviour are not well described. In the present study, different groups of human vertebral cancellous bone were exposed to cyclic compression. The inital modulus and therefore lifetimes were found to be highly dependent on age. The decrease in both with increasing age was much more pronounced in specimens which were not aligned with the main physiological axis. This implies that old bone is much more sensitive to (cyclic) failure loads in general but particularly to loads which are not coincident with the physiological main axis. KW - Knochenbruch KW - Spongiosa KW - Alter KW - Anisotropie Y1 - 2008 SP - 68 EP - 74 PB - IOS Press ER -