TY - CHAP A1 - Khaled, W. A1 - Reichling, S. A1 - Bruhns, Otto T. A1 - Monkman, Gareth J. A1 - Egersdörfer, Stefan A1 - Baumann, Michael A1 - Böse, Holger A1 - Klein, Dagmar A1 - Freimuth, Herbert A1 - Tunayar, A. A1 - Lorenz, A. A1 - Pessavento, A. A1 - Ermert, Helmut T1 - Palpation Imaging using a Haptic System for Virtual Reality Applications in Medicine T2 - Proceedings of the 12th Annual Medicine Meets Virtual Reality Conference: - Building a Better You: The Next Tools for Medical Education, Diagnosis, and Care. - Medicine Meets Virtual Reality (MMVR) - Newport Beach (California, USA). 2004 Y1 - 2004 ER - TY - CHAP A1 - Khaled, W. A1 - Bruhns, Otto T. A1 - Reichling, S. A1 - Böse, Holger A1 - Baumann, Michael A1 - Monkman, Gareth J. A1 - Egersdörfer, Stefan A1 - Meier, Alexander A1 - Freimuth, Herbert A1 - Tunayar, A. A1 - Ermert, Helmut T1 - A New Haptic Sensor Actuator System for Virtual Reality Applications in Medicine T2 - Medical Image Computing and Computer-Assisted Intervention - MICCAI 2003: 6th International Conference, Montréal, Canada, November 15-18, 2003, Proceedings Y1 - 2003 SN - 978-3540204626 SP - 132 EP - 140 PB - Springer ER - TY - JOUR A1 - Khaled, W. A1 - Bruhns, Otto T. A1 - Reichling, S. A1 - Böse, Holger A1 - Baumann, Michael A1 - Monkman, Gareth J. A1 - Egersdörfer, Stefan A1 - Meier, Alexander A1 - Klein, Dagmar A1 - Freimuth, Herbert A1 - Ermert, Helmut T1 - A haptic system for virtual reality applications based on ultrasound elastography and electrorheological fluids JF - Acoustical Imaging Y1 - 2004 U6 - https://doi.org/10.1007/978-1-4020-2402-3_85 IS - 27 SP - 667 EP - 675 PB - Kluver Academic CY - Dordrecht & New York ER - TY - CHAP A1 - Khaled, W. A1 - Reichling, S. A1 - Bruhns, Otto T. A1 - Ermert, Helmut A1 - Monkman, Gareth J. A1 - Egersdörfer, Stefan A1 - Baumann, Michael A1 - Böse, Holger A1 - Freimuth, Herbert A1 - Tunayar, A. T1 - Palpation imaging using a haptic sensor actuator system for medical applications T2 - Actuator 2004 : 9th International Conference on New Actuators & 3rd International Exhibition on Smart Actuators and Drive Systems, 14-16 June 2004, Bremen, Germany Y1 - 2004 SP - 379 EP - 382 PB - HVG Hanseatische Veranstaltungs-GmbH CY - Bremen ER - TY - JOUR A1 - Mayer, Matthias A1 - Rabindranath, Raman A1 - Börner, Juliane A1 - Hörner, Eva A1 - Bentz, Alexander A1 - Salgado, Josefina A1 - Han, Hong A1 - Böse, Holger A1 - Probst, Jörn A1 - Shamonin (Chamonine), Mikhail A1 - Monkman, Gareth J. A1 - Schlunck, Günther T1 - Ultra-Soft PDMS-Based Magnetoactive Elastomers as Dynamic Cell Culture Substrata JF - PLoS ONE N2 - Mechanical cues such as extracellular matrix stiffness and movement have a major impact on cell differentiation and function. To replicate these biological features in vitro, soft substrata with tunable elasticity and the possibility for controlled surface translocation are desirable. Here we report on the use of ultra-soft (Young’s modulus <100 kPa) PDMS-based magnetoactive elastomers (MAE) as suitable cell culture substrata. Soft non-viscous PDMS (<18 kPa) is produced using a modified extended crosslinker. MAEs are generated by embedding magnetic microparticles into a soft PDMS matrix. Both substrata yield an elasticity-dependent (14 vs. 100 kPa) modulation of α-smooth muscle actin expression in primary human fibroblasts. To allow for static or dynamic control of MAE material properties, we devise low magnetic field (≈40 mT) stimulation systems compatible with cell-culture environments. Magnetic field-instigated stiffening (14 to 200 kPa) of soft MAE enhances the spreading of primary human fibroblasts and decreases PAX-7 transcription in human mesenchymal stem cells. Pulsatile MAE movements are generated using oscillating magnetic fields and are well tolerated by adherent human fibroblasts. This MAE system provides spatial and temporal control of substratum material characteristics and permits novel designs when used as dynamic cell culture substrata or cell culture-coated actuator in tissue engineering applications or biomedical devices. Y1 - 2013 U6 - https://doi.org/10.1371/journal.pone.0076196 VL - 8 IS - 10 PB - PLOS ER - TY - JOUR A1 - Forster, Eva A1 - Mayer, Matthias A1 - Rabindranath, Raman A1 - Böse, Holger A1 - Schlunck, Günther A1 - Monkman, Gareth J. A1 - Shamonin (Chamonine), Mikhail T1 - Patterning of ultrasoft, agglutinative magnetorheological elastomers JF - Journal of applied polymer science N2 - A low-cost wax-cast molding technique for structuring ultrasoft (Young’s modulus ≤ 40 kPa), agglutinative magnetorheological elastomer (MRE) material is presented. MRE structures ranging from a few millimeters down to the micrometer range with highly reproducible results are possible. Semitransparent MREs are also fabricated and their surfaces modified accordingly. This method opens new possibilities for MREs in biomedical engineering and microfluidic applications. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013 Y1 - 2013 U6 - https://doi.org/10.1002/app.38500 VL - 128 IS - 4 SP - 2508 EP - 2515 PB - Wiley CY - New York, NY ER - TY - JOUR A1 - Klein, Dagmar A1 - Freimuth, Herbert A1 - Monkman, Gareth J. A1 - Egersdörfer, Stefan A1 - Meier, Alexander A1 - Böse, Holger A1 - Baumann, Michael A1 - Ermert, Helmut A1 - Bruhns, Otto T. T1 - Electrorheological Tactile Elements JF - Mechatronics N2 - The use of ultrasound systems for medical examination and diagnosis is nothing new. The extension of ultrasound techniques for real time elastographic analysis purposes represents a more recent development. Nevertheless, as they stand all such techniques rely on the interpretation of two-dimensional visual data displayed on a video screen. In reality however, a medical doctor will make as much use of exploratory touch as he or she does vision, making the simultaneous portrayal of both video and tactile information most desirable [Böse H, Monkman GJ, Freimuth H, Ermert H. Haptisches Sensor-Aktor-System uaf der grundlage der Echtzeitelastographie sowie von elktro- und magnetorheologischen Materialien “HASASEM” [3]. BMBF Antrag 01 IR A14D, Oktober 2000]. This paper discusses the preliminary tests and basic design parameters for single tactels using electrorheological fluids. The final aim is to produce a prototype three-dimensional tactile display comprising electrically switchable micro-machined cells whose mechanical moduli are governed by phase changes experienced by electrorheological fluids. This will be integrated with the latest elastographic ultrasonic sensor systems in order to present the human fingers with controllable surfaces capable of emulating biological tissue, muscle and bone. Y1 - 2005 U6 - https://doi.org/10.1016/j.mechatronics.2004.05.007 VL - 15 IS - 7 SP - 883 EP - 897 PB - Pergamon CY - Oxford ER - TY - JOUR A1 - Klein, Dagmar A1 - Rensink, D. A1 - Freimuth, Herbert A1 - Monkman, Gareth J. A1 - Egersdörfer, Stefan A1 - Böse, Holger A1 - Baumann, Michael T1 - Modelling the Response of a Tactile Array using an Electrorheological Fluids JF - Journal of Physics D: Applied Physics N2 - This paper reports the first step in the development of a tactile array suitable for the presentation of haptic information in virtual reality. The system is based on the electric field dependence of the viscosity of electrorheological fluids. The simulation, as well as the experimental realization of single tactels is described. The mathematical approach is based on the Eckart model (Eckart W 2000 Continuum Mech. Thermodyn. 12 341–62) and its validity is demonstrated by comparing the resulting yield stress with the experimental results from Wunderlich (2000 Dissertation Universität Erlangen-Nürnberg). Two different tactel designs are realized and the experimental results are compared with numerical simulation. The design of modification B is shown to be applicable for the realization of an actuator array with high spatial resolution. Y1 - 2004 U6 - https://doi.org/10.1088/0022-3727/37/5/023 SN - 1361-6463 SN - 0022-3727 VL - 37 IS - 5 SP - 794 EP - 803 PB - IOP Publ. CY - Bristol ER - TY - CHAP A1 - Zappa, O. A1 - Monkman, Gareth J. A1 - Egersdörfer, Stefan A1 - Datzer, G. A1 - Kahled, W. A1 - Böse, Holger A1 - Tunayar, A. T1 - High Voltage Switching using Bulk GaAs T2 - Actuator 2004 : 9th International Conference on New Actuators & 3rd International Exhibition on Smart Actuators and Drive Systems, 14-16 June 2004, Bremen, Germany Y1 - 2004 PB - HVG Hanseatische Veranstaltungs-GmbH CY - Bremen ER - TY - CHAP A1 - Egersdörfer, Stefan A1 - Schumm, M. A1 - Kessler, C. A1 - Monkman, Gareth J. A1 - Böse, Holger T1 - Smart Fluids für die Schnittstelle Mensch-Maschine der Zukunft T2 - International Mechatronik Forum, Linz Y1 - 2006 SP - 421 EP - 428 ER -