TY - CHAP A1 - Fischer, Johannes T1 - Miniaturisierter plasmonischer Sensor für das Monitoring von Weichmachern in Gewässerproben T2 - 7. MikroSystemTechnik Kongress "MEMS, Mikroelektronik, Systeme", 23.-25. Oktober 2017, München Y1 - 2017 SN - 978-3-8007-4491-6 PB - VDE-Verlag CY - Berlin ER - TY - CHAP A1 - Hausler, Peter A1 - Genslein, Christa A1 - Roth, Carina A1 - Hirsch, Thomas A1 - Bierl, Rudolf T1 - Mikro-Opto-Elektro-Mechanisches Sensorsystem zur Oberflächenplasmonenresonanzspektroskopie T2 - MikroSystemTechnik Kongress 2017 : MEMS, Mikroelektronik, Systeme 23.-25. Oktober 2017 in München N2 - Gezeigt wird die Miniaturisierung eines Messsystems für Oberflächenplasmonenresonanzspektroskopie (SPR), einer markierungs-, sowie zerstörungsfreien als auch hoch sensitiven Technologie. Aufgrund der hohen Kosten klassischer SPR-Geräte wird sie bisher jedoch vornehmlich in der Bio- und Medizintechnik eingesetzt. Das Messprinzip ermöglicht die Erfassung von Brechungsindexänderungen nahe einer Oberfläche. Der Transfer dieser Technologie von Laborgeräten hin zu einem miniaturisierten Sensorsystem senkt die Kosten, macht das System robuster und ermöglicht so ein wesentlich breiteres Anwendungsspektrum. Ein sehr vielversprechendes Merkmal des hier vorgestellten Systems ist die Möglichkeit den SPR-Effekt winkelabhängig zur Lichtquelle ohne bewegliche Bauteile zu verfolgen. The miniaturization of Surface Plasmon Resonance (SPR) technology, which mainly finds its applications in pharmaceutical screening and biotechnology so far, is described. SPR spectroscopy is a label-free, non destructive and highly sensitive measurement principle which is capable of detecting changes in the refractive index in striking distance to a gold surface. A transfer of this technology to a miniaturized sensor will broaden the range of possible applications. A promising feature which is included in the miniaturized system is the angle-dependent recording of the SPR signals without moving parts. KW - Bewegungselement KW - Biotechnik KW - Brechungsindex KW - Goldoberfläche KW - Laborgerät KW - Lichtquelle KW - Medizintechnik KW - Messprinzip KW - Messsystem KW - Miniaturisierung KW - Oberflächenplasmon KW - Oberflächenplasmonenresonanzspektroskopie KW - pharmazeutisches Screening KW - Sensorsystem KW - Spektroskopie Y1 - 2017 SN - 978-3-8007-4491-6 IS - CD-ROM SP - 645 EP - 647 PB - VDE-Verlag CY - Berlin ER - TY - CHAP A1 - Gaida, Peter A1 - Weigl, Stefan A1 - Rück, Thomas A1 - Bierl, Rudolf T1 - Portable photoakustische Messeinheit zur NO2 Detektion im Spurenbereich T2 - 7. MikroSystemTechnik Kongress "MEMS, Mikroelektronik, Systeme", 23.-25. Oktober 2017, München Y1 - 2017 SN - 978-3-8007-4491-6 PB - VDE-Verlag CY - Berlin ER - TY - JOUR A1 - Genslein, Christa A1 - Hausler, Peter A1 - Kirchner, Eva-Maria A1 - Bierl, Rudolf A1 - Baeumner, Antje J. A1 - Hirsch, Thomas T1 - Graphene-enhanced plasmonic nanohole arrays for environmental sensing in aqueous samples JF - Beilstein Journal of Nanotechnology N2 - The label-free nature of surface plasmon resonance techniques (SPR) enables a fast, specific, and sensitive analysis of molecular interactions. However, detection of highly diluted concentrations and small molecules is still challenging. It is shown here that in contrast to continuous gold films, gold nanohole arrays can significantly improve the performance of SPR devices in angle-dependent measurement mode, as a signal amplification arises from localized surface plasmons at the nanostructures. This leads consequently to an increased sensing capability of molecules bound to the nanohole array surface. Furthermore, a reduced graphene oxide (rGO) sensor surface was layered over the nanohole array. Reduced graphene oxide is a 2D nanomaterial consisting of sp2-hybridized carbon atoms and is an attractive receptor surface for SPR as it omits any bulk phase and therefore allows fast response times. In fact, it was found that nanohole arrays demonstrated a higher shift in the resonance angle of 250–380% compared to a continuous gold film. At the same time the nanohole array structure as characterized by its diameter-to-periodicity ratio had minimal influence on the binding capacity of the sensor surface. As a simple and environmentally highly relevant model, binding of the plasticizer diethyl phthalate (DEP) via π-stacking was monitored on the rGO gold nanohole array realizing a limit of detection of as low as 20 nM. The concentration-dependent signal change was studied with the best performing rGO-modified nanohole arrays. Compared to continuous gold films a diameter-to-periodicity ratio (D/P) of 0.43 lead to a 12-fold signal enhancement. Finally, the effect of environmental waters on the sensor was evaluated using samples from sea, lake and river waters spiked with analytically relevant amounts of DEP during which significant changes in the SPR signal are observed. It is expected that this concept can be successfully transferred to enhance the sensitivity in SPR sensors. KW - diethyl phthalate KW - environmental sensing KW - nanohole array KW - nanosphere lithography KW - surface plasmon resonance Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:355-epub-398623 IS - 7 SP - 1564 EP - 1573 ER - TY - CHAP A1 - Holler, Sven A1 - Hausler, Peter A1 - Roth, Carina A1 - Bierl, Rudolf T1 - Gestapelte Au-Al-Au und Au-Ag-Au Schichten als aktive Schichten für die Oberflächenplasmonenresonanzspektroskopie T2 - 5. Landshuter Symposium Mikrosystemtechnik, März 2016 Y1 - 2016 SN - 978-3-9812696-9-7 SP - 192 EP - 198 PB - Fachhochschule Landshut CY - Landshut ER - TY - CHAP A1 - Roth, Carina A1 - Hausler, Peter A1 - Bierl, Rudolf T1 - Einbindung eines CMOS-Detektors in einen hochintegrierten SPR-Sensor T2 - 5. Landshuter Symposium Mikrosystemtechnik, März 2016 Y1 - 2016 SN - 78-3-9812696-9-7 SP - 200 EP - 205 PB - Fachhochschule Landshut CY - Landshut ER - TY - CHAP A1 - Hausler, Peter A1 - Holler, Sven A1 - Hirsch, Thomas A1 - Bierl, Rudolf T1 - Miniaturisierte Oberflächenplasmonenresonanz Sensorplattform T2 - MEMS, Mikroelektronik, Systeme, MikroSystemTechnik Kongress 2015, 26.- 28. Oktober 2015, Karlsruhe, proceedings Y1 - 2015 SN - 978-3-8007-4100-7 PB - VDE Verlag CY - Berlin ER - TY - CHAP A1 - Helm, C. A1 - Deubzer, Michael A1 - Mottok, Jürgen ED - Ivanov, Artem ED - Bicker, Marc ED - Patzelt, Peter T1 - Analyse der Echtzeiteigenschaften von Multicore Speicherarchitekturen in Eingebetteten Systemen mittels einer konfigurierbaren Simulationssoftware T2 - 4. Landshuter Symposium Mikrosystemtechnik : Mikrosystemtechnik als Schlüsseltechnologie der Systemintegration, Tagungsband zum Symposium 12./13. März 2014, Hochschule Landshut Y1 - 2014 SN - 978-3-9812696-5-9 SP - 109 EP - 117 CY - Landshut ER - TY - CHAP A1 - Altmann, Andreas A1 - Birkner, Wolfgang A1 - Häckl, Franz-Xaver A1 - Hanner, Christopher A1 - Liebhart, Peter A1 - Metschl, Samuel A1 - Weck, Florian A1 - Farmbauer, Michael A1 - Heiß, Manfred A1 - Cuno, H.-H. A1 - Fuhrmann, Thomas A1 - Mandl, Roland A1 - Mottok, Jürgen A1 - Niemetz, Michael T1 - Payload development and launch of a stratosphere balloon mission T2 - IEEE Global Engineering Education Conference (EDUCON 2014), 3-5 April 2014, Istanbul, Turkey N2 - During a student project a stratosphere balloon was developed and launched. This project included the definition of the balloon parameters and the scientific instruments for performing atmospheric measurements, the development of all mechanical and electronic parts, the administration of the project as well as the management tasks related to the balloon launch. The main challenge for the students was the high complexity of the project due to tasks involving many different knowledge domains and the long project duration from the initial definition to the launch. Y1 - 2014 U6 - https://doi.org/10.1109/EDUCON.2014.6826065 ER - TY - CHAP A1 - Schäfer, Felix ED - Mottok, Jürgen ED - Reichenberger, Marcus ED - Bogner, Werner T1 - Temperature Measurement with Scanner-Integrated Pyrometer during Laser Transmission Welding with Clearweld Absorber T2 - Applied Research Conference 2018, ARC 2018, 10 July 2018, Deggendorf Y1 - 2018 SP - 258 EP - 260 PB - pro Business GmbH CY - Berlin ER - TY - CHAP A1 - Maiwald, Frederik ED - Mottok, Jürgen ED - Reichenberger, Marcus ED - Bogner, Werner T1 - Simulation of Pyrometer Based Temperature Measurement Systems using Non-Sequential Raytracing T2 - Applied Research Conference 2018, ARC 2018, 10 July 2018, Deggendorf Y1 - 2018 SP - 168 EP - 171 PB - pro Business GmbH CY - Berlin ER - TY - CHAP A1 - Quandt, Benjamin ED - Mottok, Jürgen ED - Reichenberger, Marcus ED - Bogner, Werner T1 - Effect of the Detection Spot Size on pyrometric Temperature Signal at quasi-simultaneous Laser Transmission Welding T2 - Applied Research Conference 2018, ARC 2018, 10 July 2018, Deggendorf Y1 - 2018 SP - 261 EP - 264 PB - pro Business GmbH CY - Berlin ER - TY - JOUR A1 - van der Weerd, Bastiaan A1 - Bierl, Rudolf A1 - Matysik, Frank-Michael T1 - Trends in Electrochemical Sensing of Blood Gases JF - Bioanalytical Reviews N2 - The monitoring of partial pressures of the blood gases carbon dioxide (pCO2) and oxygen (pO2) is of great importance in clinical diagnostics. The measure of pCO2 and pO2 provides essential information about the patient’s metabolism, gas exchange, ventilation, and acid–base homeostasis. The conventional electrochemical methods for clinical blood gas analysis are based on the potentiometric Severinghaus sensor for carbon dioxide and the amperometric Clark sensor for oxygen. These techniques are well established and are only shortly discussed in this overview. However, in recent years a variety of modifications of these classical sensor concepts and new approaches of electrochemical sensing of pCO2 and pO2 have been introduced. This review summarizes recent developments in this field and discusses the potential for future applications in clinical blood gas analysis. KW - Blood gas analysis KW - Noninvasive blood gas sensor KW - Electrochemical sensor KW - Clinical analysis Y1 - 2016 U6 - https://doi.org/10.1007/11663_2016_1 VL - 6 SP - 263 EP - 280 PB - Springer CY - Berlin ER -