TY - JOUR A1 - Borgetto, Bernhard A1 - Tomlin, George S. A1 - Max, Susanne A1 - Gantschnig, Brigitte Elisabeth A1 - Pfingsten, Andrea T1 - Die Forschungspyramide. Teil 2: Methodologische Grundlagen: Kausalität und externe Evidenz JF - Ergoscience N2 - Um die medizinische und therapeutische Versorgung von Patienten kontinuierlich zu optimieren, wird von Angehörigen der Gesundheitsberufe, therapeutischen Teams und Versorgungseinrichtungen gefordert, wissenschaftliche Erkenntnisse (externe Evidenz) in die tägliche Praxis zu integrieren und auf den jeweiligen Patientenfall abzustimmen. Die Aufbereitung, Systematisierung und Bewertung der externen Evidenz orientiert sich dabei klassischerweise an eindimensionalen Evidenzhierarchien, die vorwiegend quantitativ-experimentelle Studiendesigns berücksichtigen. In diesem Beitrag wird die Orientierung an klassischen eindimensionalen Evidenzhierarchien kritisch hinterfragt. Als Alternative wird das Modell und die Systematik der Forschungspyramide vorgestellt, die Evidenz aus unterschiedlichen Forschungsansätzen umfassend berücksichtigt und dennoch methodologisch streng beurteilt. Der Einbezug beobachtender und qualitativer Studien stellt dahingehend eine besondere Praxisnähe her. Y1 - 2017 U6 - https://doi.org/10.1007/978-3-662-58314-2_58 VL - 12 IS - 3 SP - 90 EP - 101 PB - Springer CY - Berlin, Heidelberg ER - TY - JOUR A1 - Borgetto, Bernhard A1 - Tomlin, George S. A1 - Max, Susanne A1 - Gantschnig, Brigitte Elisabeth A1 - Pfingsten, Andrea T1 - Die Forschungspyramide. Teil 3: Grundlagen der Anwendung für die kritische Evidenzbewertung JF - Ergoscience N2 - Die Forschungspyramide ist ein Modell zur Bewertung und Zusammenführung von externer Evidenz aus unterschiedlichen Forschungsansätzen. Sie bietet eine Grundlage zur Aufbereitung und Systematisierung von Forschungsergebnissen, um, basierend auf wissenschaftlicher Evidenz, ergotherapeutische Fragestellungen zu beantworten und ergotherapeutische Entscheidungen in der alltäglichen Praxis zu treffen. Dieser Beitrag arbeitet die Grundlagen der praktischen Anwendung des Modells auf: die Evidenzbewertung im Modell der Forschungspyramide, die Bewertung der Durchführungsqualität von quantitativen und qualitativen Studien und die Durchführung von Pyramiden-Reviews. The Research Pyramid is a model that values and integrates external evidence from multiple research approaches. It provides a basis to collect and synthesize research findings for answering questions that emerge in occupational therapy practice and for subsequent decision making, based on research evidence. In this article, the application principles that underlie the model are presented: the principles of the appraisal of evidence according to the research pyramid, the procedural quality of quantitative and qualitative studies and the administration of pyramid reviews. KW - Research pyramid KW - Quantitiative study KW - Qualitative study KW - Procedural quality KW - Pyramdid review Y1 - 2017 U6 - https://doi.org/10.2443/skv-s-2017-54020170401 VL - 12 IS - 4 SP - 134 EP - 143 PB - Schulz-Kirchner-Verlag ER - TY - CHAP A1 - Borgetto, Bernhard A1 - Tomlin, George S. A1 - Max, Susanne A1 - Brinkmann, Melanie A1 - Spitzer, Lena A1 - Pfingsten, Andrea ED - Haring (Hrsg.), Robin T1 - Evidenz in der Gesundheitsversorgung : Die Forschungspyramide T2 - Gesundheitswissenschaften N2 - Um die medizinische und therapeutische Versorgung von Patienten kontinuierlich zu optimieren, wird von Angehörigen der Gesundheitsberufe, therapeutischen Teams und Versorgungseinrichtungen gefordert, wissenschaftliche Erkenntnisse (externe Evidenz) in die tägliche Praxis zu integrieren und auf den jeweiligen Patientenfall abzustimmen. Die Aufbereitung, Systematisierung und Bewertung der externen Evidenz orientiert sich dabei klassischerweise an eindimensionalen Evidenzhierarchien, die vorwiegend quantitativ-experimentelle Studiendesigns berücksichtigen. In diesem Beitrag wird die Orientierung an klassischen eindimensionalen Evidenzhierarchien kritisch hinterfragt. Als Alternative wird das Modell und die Systematik der Forschungspyramide vorgestellt, die Evidenz aus unterschiedlichen Forschungsansätzen umfassend berücksichtigt und dennoch methodologisch streng beurteilt. Der Einbezug beobachtender und qualitativer Studien stellt dahingehend eine besondere Praxisnähe her. Y1 - 2019 U6 - https://doi.org/10.1007/978-3-662-54179-1_58-1 SP - 643 EP - 654 PB - Springer CY - Berlin, Heidelberg ER - TY - JOUR A1 - Schüßler, Beate A1 - Pfingsten, Andrea A1 - Schöttker-Königer, Thomas T1 - Intertester-Reliabilität des Upper Limb Neural Tension Tests (ULNT) 1 JF - manuelletherapie N2 - Zur Überprüfung der Nervenleitfähigkeit werden Kraft, Reflexe und Sensibilität getestet. Bei der Untersuchung der Mechanosensitivität eines Nervs kommen neurodynamische Tests zum Einsatz. Der Upper Limb Neural Tension Test (ULNT) 1 bestimmt die Mechanosensitivität des N. medianus. Ziel der Studie war die Untersuchung der Intertester-Reliabilität des ULNT 1 von nicht spezialisierten Physiotherapeuten bei Probanden mit unilateralen Nacken- und/oder Armsymptomen. Die Therapeuten beurteilten binar und metrisch die Kriterien patientenspezifische Symptome, strukturelle Differenzierung und Bewegungsausmaß sowie das Gesamtergebnis bei 33 Patienten mit unilateralen Nacken- und/oder Armsymptomen. Bei den binaren Daten bestimmte der Fleiss-Kappa und bei den metrischen Daten der Intraklassen-Korrelationskoeffizient die Reliabilität. Die zusätzlich erstellten Regressionsmodelle sollten den Einfluss der einzelnen Beurteilungskriterien auf die Gesamtentscheidung herausfiltern. Mit Ausnahme der Reproduzierbarkeit patientenspezifischer Symptome scheint die Beurteilung des ULNT 1 durch nicht spezialisierte Therapeuten nur schlecht vergleichbar zu sein. Da die metrische Bewertungsweise die individuellen Schwellenwerte besser darstellt, ist diese der binaren vorzuziehen. T2 - Inter-Tester Reliability of the Upper Limb Neural Tension Tests (ULNT) 1 KW - ULNT 1 KW - Intertester-Reliabilität KW - Nackensymptome KW - Armsymptome Y1 - 2019 U6 - https://doi.org/10.1055/A-0816-0000 VL - 23 IS - 2 SP - 77 EP - 82 PB - Georg Thieme Verlag ER - TY - JOUR A1 - Borgetto, Bernhard A1 - Räbiger, Jutta A1 - Rottenecker, Joachim A1 - Hansen, Hilke A1 - Pfingsten, Andrea A1 - Wasner, Mieke T1 - Akademisierung: Die vollständige hochschulische Ausbildung in der Ergotherapie, Logopädie und Physiotherapie ist notwendig und machbar JF - physioscience N2 - Im Jahr 2018 haben wir bildungs-, gesundheits- und berufspolitisch bewegte Zeiten durchlebt. Politische Spitzentreffen wechselten sich mit Informationsveranstaltungen für Parlamentarier ab, die Ausbildung und die berufliche Situation wurden in Trippelschritten reformiert, immer gerade nur so weit, wie es die Hoffnung auf Verringerung des politischen Drucks in Bund und Ländern seitens der Regierenden als nötig erscheinen lässt. Die Ausbildungsflickschusterei in den Therapieberufen von der (Teil-)Abschaffung des Schulgeldes bis zur Zahlung einer Ausbildungsvergütung für einen kleinen Teil der Schülerschaft scheint aber eher die Unruhe zu nähren. In dieser Situation ist es etwas Besonderes, dass umfassende konzeptionelle Perspektiven zu den anstehenden Reformen der Ausbildung und Berufsgesetze entwickelt werden und eine breite verbandliche Unterstützung finden. Das Strategiepapier des Hochschulverbunds Gesundheitsfachberufe (HVG) und des Verbunds für Ausbildung und Studium in den Therapieberufen (VAST) begründet und belegt die Notwendigkeit und Machbarkeit der vollständigen hochschulischen Ausbildung in der Ergotherapie, Logopädie und Physiotherapie in primärqualifizierenden Studiengängen mit einem Übergangszeitraum von 10 – 15 Jahren. (Der HVG ist ein Zusammenschluss von 38 Hochschulen mit Therapiestudiengängen und 18 Berufsfachschulen, die in Kooperation mit Hochschulen Studiengänge mitgestalten. In VAST sind derzeit 5 Schul- bzw. Lehrerverbände organisiert). Der Deutsche Verband für Physiotherapie (ZVK), der Bundesverband selbstständiger Physiotherapeuten (IFK) und der Verband Physikalische Therapie (VPT) unterstützen dieses Ziel. Diese Einigkeit ist neu und sehr erfreulich; besonders bemerkenswert ist jedoch, dass auch die Mitgliedsverbände des VAST das Papier unterstützen. Die in VAST organisierten Schul- bzw. Lehrerverbände der Therapieberufe (u.a. der Verband der leitenden Lehrkräfte in der Physiotherapie (VLL)) stellen damit die bisherige traditionelle Rolle der Schulen als Ausbildungsinstitutionen mit dem Ziel einer adäquaten Weiterentwicklung der Ausbildung zur Disposition. T2 - Academisation: The Complete Academic Education in Occupational Therapy, Logopedia and Physiotherapy is Necessary and Feasible Y1 - 2019 U6 - https://doi.org/10.1055/a-0832-9668 VL - 15 IS - 1 SP - 41 EP - 42 PB - Thieme ER - TY - GEN A1 - Scheppach, Markus W. A1 - Rauber, David A1 - Mendel, Robert A1 - Palm, Christoph A1 - Byrne, Michael F. A1 - Messmann, Helmut A1 - Ebigbo, Alanna T1 - Detection Of Celiac Disease Using A Deep Learning Algorithm T2 - Endoscopy N2 - Aims Celiac disease (CD) is a complex condition caused by an autoimmune reaction to ingested gluten. Due to its polymorphic manifestation and subtle endoscopic presentation, the diagnosis is difficult and thus the disorder is underreported. We aimed to use deep learning to identify celiac disease on endoscopic images of the small bowel. Methods Patients with small intestinal histology compatible with CD (MARSH classification I-III) were extracted retrospectively from the database of Augsburg University hospital. They were compared to patients with no clinical signs of CD and histologically normal small intestinal mucosa. In a first step MARSH III and normal small intestinal mucosa were differentiated with the help of a deep learning algorithm. For this, the endoscopic white light images were divided into five equal-sized subsets. We avoided splitting the images of one patient into several subsets. A ResNet-50 model was trained with the images from four subsets and then validated with the remaining subset. This process was repeated for each subset, such that each subset was validated once. Sensitivity, specificity, and harmonic mean (F1) of the algorithm were determined. Results The algorithm showed values of 0.83, 0.88, and 0.84 for sensitivity, specificity, and F1, respectively. Further data showing a comparison between the detection rate of the AI model and that of experienced endoscopists will be available at the time of the upcoming conference. Conclusions We present the first clinical report on the use of a deep learning algorithm for the detection of celiac disease using endoscopic images. Further evaluation on an external data set, as well as in the detection of CD in real-time, will follow. However, this work at least suggests that AI can assist endoscopists in the endoscopic diagnosis of CD, and ultimately may be able to do a true optical biopsy in live-time. KW - Celiac Disease KW - Deep Learning Y1 - 2021 U6 - https://doi.org/10.1055/s-0041-1724970 N1 - Digital poster exhibition VL - 53 IS - S 01 PB - Georg Thieme Verlag CY - Stuttgart ER - TY - GEN A1 - Römmele, Christoph A1 - Mendel, Robert A1 - Rauber, David A1 - Rückert, Tobias A1 - Byrne, Michael F. A1 - Palm, Christoph A1 - Messmann, Helmut A1 - Ebigbo, Alanna T1 - Endoscopic Diagnosis of Eosinophilic Esophagitis Using a deep Learning Algorithm T2 - Endoscopy N2 - Aims Eosinophilic esophagitis (EoE) is easily missed during endoscopy, either because physicians are not familiar with its endoscopic features or the morphologic changes are too subtle. In this preliminary paper, we present the first attempt to detect EoE in endoscopic white light (WL) images using a deep learning network (EoE-AI). Methods 401 WL images of eosinophilic esophagitis and 871 WL images of normal esophageal mucosa were evaluated. All images were assessed for the Endoscopic Reference score (EREFS) (edema, rings, exudates, furrows, strictures). Images with strictures were excluded. EoE was defined as the presence of at least 15 eosinophils per high power field on biopsy. A convolutional neural network based on the ResNet architecture with several five-fold cross-validation runs was used. Adding auxiliary EREFS-classification branches to the neural network allowed the inclusion of the scores as optimization criteria during training. EoE-AI was evaluated for sensitivity, specificity, and F1-score. In addition, two human endoscopists evaluated the images. Results EoE-AI showed a mean sensitivity, specificity, and F1 of 0.759, 0.976, and 0.834 respectively, averaged over the five distinct cross-validation runs. With the EREFS-augmented architecture, a mean sensitivity, specificity, and F1-score of 0.848, 0.945, and 0.861 could be demonstrated respectively. In comparison, the two human endoscopists had an average sensitivity, specificity, and F1-score of 0.718, 0.958, and 0.793. Conclusions To the best of our knowledge, this is the first application of deep learning to endoscopic images of EoE which were also assessed after augmentation with the EREFS-score. The next step is the evaluation of EoE-AI using an external dataset. We then plan to assess the EoE-AI tool on endoscopic videos, and also in real-time. This preliminary work is encouraging regarding the ability for AI to enhance physician detection of EoE, and potentially to do a true “optical biopsy” but more work is needed. KW - Eosinophilic Esophagitis KW - Endoscopy KW - Deep Learning Y1 - 2021 U6 - https://doi.org/10.1055/s-0041-1724274 VL - 53 IS - S 01 PB - Georg Thieme Verlag CY - Stuttgart ER - TY - INPR A1 - Weiherer, Maximilian A1 - Eigenberger, Andreas A1 - Brébant, Vanessa A1 - Prantl, Lukas A1 - Palm, Christoph T1 - Learning the shape of female breasts: an open-access 3D statistical shape model of the female breast built from 110 breast scans N2 - We present the Regensburg Breast Shape Model (RBSM) – a 3D statistical shape model of the female breast built from 110 breast scans, and the first ever publicly available. Together with the model, a fully automated, pairwise surface registration pipeline used to establish correspondence among 3D breast scans is introduced. Our method is computationally efficient and requires only four landmarks to guide the registration process. In order to weaken the strong coupling between breast and thorax, we propose to minimize the variance outside the breast region as much as possible. To achieve this goal, a novel concept called breast probability masks (BPMs) is introduced. A BPM assigns probabilities to each point of a 3D breast scan, telling how likely it is that a particular point belongs to the breast area. During registration, we use BPMs to align the template to the target as accurately as possible inside the breast region and only roughly outside. This simple yet effective strategy significantly reduces the unwanted variance outside the breast region, leading to better statistical shape models in which breast shapes are quite well decoupled from the thorax. The RBSM is thus able to produce a variety of different breast shapes as independently as possible from the shape of the thorax. Our systematic experimental evaluation reveals a generalization ability of 0.17 mm and a specificity of 2.8 mm for the RBSM. Ultimately, our model is seen as a first step towards combining physically motivated deformable models of the breast and statistical approaches in order to enable more realistic surgical outcome simulation. KW - Statistical shape mode KW - Surgical outcome simulation KW - 3D breast scan registration KW - Non-rigid surface registration KW - Breast imaging Y1 - 2021 ER - TY - VIDEO A1 - Auer, Simon A1 - Reinker, Lukas A1 - Süß, Franz A1 - Kubowitsch, Simone A1 - Krutsch, Werner A1 - Weber, Markus A1 - Renkawitz, Tobias A1 - Dendorfer, Sebastian T1 - Webcast: Effect of mental demand on leg loading in highly dynamic motion N2 - Football players have a high risk of leg muscle injuries, especially when exposed to mental stress. Injuries to muscles of the thigh are common in amateur and professional football, representing almost a third of all injuries. These injuries occur primarily in non-contact situations and from overuse. They can lead to a range of costs, including financial costs associated with treatment as well as those associated with long-term recovery, and absence from training and/or competition. Further, there is a high risk of injury recurrence and subsequent injury. KW - Webcast KW - AnyBody KW - Stress KW - Football KW - Speedcourt Y1 - 2020 UR - https://www.youtube.com/watch?v=uSc_9XlnkaA ER - TY - VIDEO A1 - Melzner, Maximilian A1 - Engelhardt, Lucas T1 - AnyBody Webcast - A new musculoskeletal AnyBody™ detailed hand model Y1 - 2020 UR - https://www.youtube.com/watch?v=E4xnbjRJYm8&t=631s ER - TY - GEN A1 - Melzner, Maximilian A1 - Ismail, Khaled M. A1 - Rušavý, Zdeněk A1 - Kališ, Vladimír A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Musculoskeletal Lower Back Load of Accoucheurs During Delivery T2 - 26th Congress of the European Society of Biomechanics, July 11-14, 2021, Milan, Italy N2 - With the progress in modern medicine, it was possible to significantly reduce the risks of birth for mother and child. One aspect that has received less attention so far is the risk of injury to the accoucheurs (obstetricians and midwives) during the birth process. Indeed, studies indicate that 92% of midwives suffer from musculoskeletal disorders, with the lower back being the main cause of complaints (72%). The aim of this study was to investigate two commonly used postural techniques used by accoucheurs during childbirth and to analyze the resulting load on the lower back using the AnyBodyTM musculoskeletal simulation software. Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-20208 CY - Milan ER - TY - GEN A1 - Auer, Simon A1 - Reinker, Lukas A1 - Dendorfer, Sebastian T1 - Evaluation of muscle recruitment and muscle models in musculoskeletal simulation of dynamic motion T2 - 26th Congress of the European Society of Biomechanics, July 11-14, 2021, Milan, Italy N2 - Musculoskeletal simulation plays an increasingly important role in sports biomechanics. In the last years, the field of application widened from orthopaedics and ergonomics to sports [1]. A muscle recruitment algorithm with a quadratic objective function is usually used to calculate muscle activity in dynamic movements. The agreement of calculated and measured thigh muscle activity has already been investigated [2]. They found a strong agreement for sprinting and running, while the correlation decreased for side-cutting manoeuvres. Nevertheless, the influence of different muscle recruitment criteria on muscle activity in dynamic musculoskeletal simulations is currently unknown. Hence, this study aimed to analyse the effect of different muscle recruitment criteria and muscle models on the correlation of numerical and measured muscle activity in highly dynamic movements. KW - esb KW - biomechanics KW - muscle recruitment Y1 - 2021 UR - https://esbiomech.org/conference/archive/2021milan/Contribution_1719.pdf CY - Milan ER - TY - INPR A1 - Weiß, Martin Georg T1 - Optimization of Cartesian Tasks with Configuration Selection N2 - A basic task in the design of an industrial robot application is the relative placement of robot and workpiece. Process points are defined in Cartesian coordinates relative to the workpiece coordinate system, and the workpiece has to be located such that the robot can reach all points. Finding such a location is still an iterative procedure based on the developers' intuition. One difficulty is the choice of one of the several solutions of the backward transform of a typical 6R robot. We present a novel algorithm that simultaneously optimizes the workpiece location and the robot configuration at all process points using higher order optimization algorithms. A key ingredient is the extension of the robot with a virtual prismatic axis. The practical feasibility of the approach is shown with an example using a commercial industrial robot. KW - optimization KW - Intralogistik KW - Industrieroboter KW - Programmgenerierung KW - Nichtlineare Optimierung KW - robotics Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-20176 UR - https://arxiv.org/pdf/1811.07137.pdf ER - TY - JOUR A1 - Klotz, Stefan A1 - Westner, Markus A1 - Strahringer, Susanne T1 - Critical Success Factors of Business-managed IT: It Takes Two to Tango JF - Information Systems Management N2 - This paper identifies critical success factors of Business-managed IT based on case study results. Four groups of critical success factors emerge: (1) general approach to Business-managed IT/Business-managed IT strategy, (2) Business-managed IT project prerequisites/Business-managed IT team, (3) Business-managed IT project execution and outcome, and (4) information technology management for Business-managed IT. The results suggest that bilateral responsibility between the business unit and the IT organization is the most favorable governance option for Business-managed IT. KW - Betriebliches Informationssystem KW - Strategisches Management KW - Erfolgsfaktor KW - Fallstudie KW - Business-managed IT KW - Shadow IT KW - critical success factors KW - IT governance KW - application governance Y1 - 2022 U6 - https://doi.org/10.1080/10580530.2021.1938300 VL - 39 IS - 3 SP - 220 EP - 240 PB - Taylor&Francis ER - TY - CHAP A1 - Brosig, Christoph A1 - Westner, Markus A1 - Strahringer, Susanne ED - Borštnar, Mirjana Kljajić T1 - Linking IT assets and competitive advantage - IT capabilities of servitized business models T2 - 34th Bled eConference Digital Support from Crisis to Progressive Change: June 27 - 30, 2021, Online: Conference Proceedings N2 - This paper connects research from business model innovation and information systems by exploring critical IT capabilities for servitized business models. The adoption of servitized business models is a major business model innovation strategy. At the same time, digitalization drives the evolution of IT capabilities at these business models. Scholars argue that it remains unclear how IT capabilities enable servitized business models to build a competitive advantage by achieving cost advantages or differentiation. This paper explores IT capabilities that enable building a competitive advantage for servitized business models based on a qualitative analysis of multiple published case studies. The authors identify configurations of IT capabilities among servitized business models. The findings contribute to servitization research by exploring IT capabilities and how they are combined among servitized business models. The insights help practitioners deploy digital technologies and IT assets effectively as building blocks of IT capabilities to advance their servitized business model. KW - resource-based view KW - IT capability KW - digital servitization KW - competitive advantage KW - Geschäftsmodell KW - Innovation KW - Hybrides Leistungsbündel KW - Informationstechnik Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-20158 UR - https://press.um.si/index.php/ump/catalog/book/581 SN - 978-961-286-485-9 SP - 111 EP - 123 ER - TY - JOUR A1 - Wulf, Frederik A1 - Westner, Markus A1 - Strahringer, Susanne T1 - Cloud Computing Adoption: A Literature Review on What Is New and What We Still Need to Address JF - Communications of the Association for Information Systems N2 - Research on cloud computing (CC) recently emerged congruently with the technology’s importance for organizations at a fast pace. This makes it difficult for practitioners to obtain a consolidated overview of what determines CC adoption based on the numerous papers in this regard. Moreover, for further research in the field to add value, it is necessary to identify what still needs to be addressed. In this vein, we conducted a descriptive review of 39 papers, integrating the results of a previous review on 23 papers from 2014, to compare findings across studies. We identify 44 determinant factors that exhibit consistent directional influence on the dependent meta-variable “CC adoption”, extending previous literature reviews with regard to asset, client, and environmental characteristics. We then critically reviewed the research landscape to identify what is there, and what is not yet covered: Future research should specifically regard the adoption of Infrastructure-, Platform-, and Everything-as-a-Service, private, hybrid, and multi-cloud deployment, investigate vendor, solution, and individual characteristics, analyzing information systems, or the decision-maker. KW - Cloud Computing KW - Literaturbericht Y1 - 2021 U6 - https://doi.org/10.17705/1CAIS.04843 SN - 1529-3181 VL - 48 IS - 1 SP - 523 EP - 561 PB - Association for Information Systems, AIS ER - TY - JOUR A1 - Wünsche, Isabel A1 - Brinkmann, Melanie A1 - Pfingsten, Andrea A1 - Borgetto, Bernhard T1 - Selbsthilfe von Menschen mit einer rheumatischen Erkrankung JF - internistische praxis N2 - Durch die wissenschaftlich fundierte Darstellung der Selbsthilfe (SH) bei rheumatischen Erkrankungen sollen mögliche Handlungsunsicherheiten im Umgang mit Selbsthilfegruppen (SHG) in der täglichen Praxis verringert werden. Welche Mechanismen in SHG wirken, wurde bisher nicht ausreichend wissenschaftlich untersucht. Im Zusammenhang mit dem gesicherten Wissen über die salutogenen und tertiärpräventiven Wirkungsweisen von Kommunikation und sozialen Bindungen, kann aus dem Stand der Selbsthilfeforschung jedoch ein allgemeines heuristisches Modell der Wirkung von SHG abgeleitet werden, welches kurz erläutert wird. Von der Weltgesundheitsorganisation werden rheumatische Erkrankungen als mehr oder weniger klar definierte Erkrankungen der Gelenke, gelenkumgebenden Strukturen und Muskel- oder Bindegewebe beschrieben, die zu schmerzhaften, häufig chronischen Einschränkungen des Bewegungsapparates führen können. Neben der fachärztlichen Versorgung besteht durch die Deutsche Rheuma-Liga (DRL) ein flächendeckendes SH-Angebot für Betroffene. Insbesondere SHG tragen zur gegenseitigen sozialen Unterstützung und zur Informationsaneignung bei den Betroffenen und in deren sozialen Umfeld bei. Sind die Ergebnisse und Schlussfolgerungen der Studien zu den Wirkungen von SH bei rheumatischen Erkrankungen aufgrund methodischer Schwierigkeiten der Wirkungsforschung auch limitiert, heben doch die meisten Forscher hervor, dass die Unterstützung durch SHG allein und in Kombination mit einer professionellen Versorgung neben vielen Einzelaspekten auch die Lebensqualität erhöht. KW - akuter Gelenkrheumatismus KW - Rheumatismus KW - Selbsthilfe KW - Muskelrheumatismus KW - rheumatische Erkrankungen KW - Rheumatismus KW - Selbsthilfe KW - Wirkmechanismen Y1 - 2019 SN - 0009–4846 VL - 61 IS - 1 SP - 56 EP - 67 PB - Mediengruppe Oberfranken - Fachverlage ER - TY - JOUR A1 - Melzner, Maximilian A1 - Suess, Franz A1 - Dendorfer, Sebastian T1 - The impact of anatomical uncertainties on the predictions of a musculoskeletal hand model – a sensitivity study JF - Computer Methods in Biomechanics and Biomedical Engineering N2 - Outputs of musculoskeletal models should be considered probabilistic rather than deterministic as they are affected by inaccuracies and estimations associated with the development of the model. One of these uncertainties being critical for modeling arises from the determination of the muscles' line of action and the physiological cross-sectional area. Therefore, the aim of this study was to evaluate the outcome sensitivity of model predictions from a musculoskeletal hand model in comparison to the uncertainty of these input parameters. For this purpose, the kinematics and muscle activities of different hand movements (abduction of the fingers, abduction of the thumb, and flexion of the thumb) were recorded. One thousand simulations were calculated for each movement using the Latin hypercube sampling method with a corresponding variation of the muscle origin/insertion points and the cross-sectional area. Comparing the standard hand to simulations incorporating uncertainties of input parameters shows no major deviations in on- and off-set time point of muscle activities. About 60% of simulations are located within a ± 30% interval around the standard model concerning joint reaction forces. The comparison with the variation of the input data leads to the conclusion that the standard hand model is able to provide not over-scattered outcomes and, therefore, can be considered relatively stable. These results are of practical importance to the personalization of a musculoskeletal model with subject-specific bone geometries and hence changed muscle line of action. KW - Biomechanik KW - Simulation Y1 - 2021 U6 - https://doi.org/10.1080/10255842.2021.1940974 SN - 1476-8259 N1 - Corresponding author: Maximilian Melzner VL - 25 IS - 2 SP - 156 EP - 164 PB - Taylor & Francis ER - TY - JOUR A1 - Souza Jr., Luis Antonio de A1 - Mendel, Robert A1 - Strasser, Sophia A1 - Ebigbo, Alanna A1 - Probst, Andreas A1 - Messmann, Helmut A1 - Papa, João Paulo A1 - Palm, Christoph T1 - Convolutional Neural Networks for the evaluation of cancer in Barrett’s esophagus: Explainable AI to lighten up the black-box JF - Computers in Biology and Medicine N2 - Even though artificial intelligence and machine learning have demonstrated remarkable performances in medical image computing, their level of accountability and transparency must be provided in such evaluations. The reliability related to machine learning predictions must be explained and interpreted, especially if diagnosis support is addressed. For this task, the black-box nature of deep learning techniques must be lightened up to transfer its promising results into clinical practice. Hence, we aim to investigate the use of explainable artificial intelligence techniques to quantitatively highlight discriminative regions during the classification of earlycancerous tissues in Barrett’s esophagus-diagnosed patients. Four Convolutional Neural Network models (AlexNet, SqueezeNet, ResNet50, and VGG16) were analyzed using five different interpretation techniques (saliency, guided backpropagation, integrated gradients, input × gradients, and DeepLIFT) to compare their agreement with experts’ previous annotations of cancerous tissue. We could show that saliency attributes match best with the manual experts’ delineations. Moreover, there is moderate to high correlation between the sensitivity of a model and the human-and-computer agreement. The results also lightened that the higher the model’s sensitivity, the stronger the correlation of human and computational segmentation agreement. We observed a relevant relation between computational learning and experts’ insights, demonstrating how human knowledge may influence the correct computational learning. KW - Deep Learning KW - Künstliche Intelligenz KW - Computerunterstützte Medizin KW - Barrett's esophagus KW - Adenocarcinoma KW - Machine learning KW - Explainable artificial intelligence KW - Computer-aided diagnosis Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-20126 SN - 0010-4825 VL - 135 SP - 1 EP - 14 PB - Elsevier ER - TY - JOUR A1 - Haug, Sonja A1 - Vetter, Miriam A1 - Weber, Karsten T1 - Gebäudesanierung zwischen Energieeffizienz und Sozialverträglichkeit BT - Zwei empirische Fallstudien JF - TATuP - Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis N2 - Die Akzeptanz unter Bewohnern und Bewohnerinnen gewinnt bei hoch komplexen, technisch anspruchsvollen energetischen Sanierungen als „Innovationsmotor“ zunehmend an Relevanz. Der Beitrag basiert auf zwei Fallstudien zur partizipativen Nutzereinbindung bei energetischen Sanierungen im genossenschaftlichen Wohnbau historischer Stadtquartiere in Regensburg. Neben einer sozialverträglichen Sanierung wurde jeweils ein hohes Maß an Energieeffizienz bei den technischen Lösungen ange-strebt. Haushaltsbefragungen und qualitative Interviews zeigen die hohe Akzeptanz von Sanierungsmaßnahmen, sofern die Senkung der Energiekosten die erhöhte Miete kompensiert. Abschließend werden Akzeptanzfaktoren wie Partizipation, Vertrauen, Sozialverträglichkeit und Autarkie erörtert. T2 - Building restoration between energy efficiency and user acceptance KW - Altbaumodernisierung KW - Energieeinsparung KW - Sozialverträglichkeit KW - Fallstudie KW - energy-efficient building restoration KW - user acceptance KW - household survey KW - historic quarter KW - renewable energy Y1 - 2020 U6 - https://doi.org/10.14512/tatup.29.3.56 SN - 2567-8833 VL - 29 IS - 3 SP - 56 EP - 63 PB - oekom-Verlag ER - TY - JOUR A1 - Haug, Sonja A1 - Vetter, Miriam T1 - Altersgerechtes Wohnen im Quartier JF - Standort - Zeitschrift für angewandte Geographie N2 - Im Alter nimmt das Quartier aufgrund geringerer Aktionsradien an Bedeutung zu. Der Beitrag befasst sich mit der Frage, welche Besonderheiten sich bei Senioren-Haushalten im Hinblick auf Wohnen und soziale Teilhabe zeigen. Aus dem Projekt MAGGIE werden Ergebnisse einer schriftlichen Haushaltsbefragung (N=195) in der Wohngenossenschaft Margaretenau Regensburg dargestellt. Hierbei wird auf die aktuelle und zukünftige Wohnsituation, den Veränderungsbedarf, den Wunsch nach Gemeinschaftsangeboten und die soziale Einbettung eingegangen. Es zeigt sich eine geringe Veränderungsbereitschaft und ein überdurchschnittlich hohes Maß an lokalem Sozialkapital. Am Ende werden Schlussfolgerungen für das Sanierungs- und Quartiersmanagement gezogen. T2 - Age-appropriate living in the neighborhood KW - Alter KW - Wohnen KW - Stadtviertel KW - Sozialraum KW - Senioren KW - Wohnsituation KW - Sozialraum KW - Lokales Sozialkapital KW - Quartiersgestaltung Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-20050 SN - 1432-220X N1 - Corresponding author: Sonja Haug VL - 45 SP - 11 EP - 17 PB - Springer Nature ER - TY - JOUR A1 - Milewski, Nadja A1 - Haug, Sonja T1 - Religious Diversity and Women’s Attitudes Toward Using Assisted Reproductive Technologies BT - Insights from a Pilot Study in Germany JF - Journal of Religion and Demography N2 - This study examines women’s attitudes toward the own use of assisted reproductive technologies (ART) by their religious affiliation in Germany. The social relevance of ART is increasing in Western countries due to overall low birth rates, a high rate of childlessness, and a gap between the desired and the actual numbers of children. Previous literature has been scarce, however, on attitudes toward ART, and religious diversity has not been included in studies on ART. Our analysis is based on data collected in a pilot study in 2014 and 2015. The sample includes 944 women aged 18 to 50 living in Germany. The results show that Muslim women were significantly more likely than Christian women to say they would consider using ART; having no religious affiliation was associated with the least open attitude toward ART usage. KW - Reproduktionsmedizin KW - Frau KW - Religion KW - Deutschland KW - social attitudes KW - fertility KW - ART KW - reproductive health KW - Germany Y1 - 2020 U6 - https://doi.org/10.1163/2589742X-12347104 SN - 2589-742X VL - 7 IS - 1 SP - 150 EP - 168 PB - Brill ER - TY - JOUR A1 - Weber, Markus A1 - Suess, Franz A1 - Jerabek, Seth A1 - Meyer, Matthias A1 - Grifka, Joachim A1 - Renkawitz, Tobias A1 - Dendorfer, Sebastian T1 - Kinematic pelvic tilt during gait alters functional cup position in total hip arthroplasty JF - Journal of Orthopaedic Research N2 - Static pelvic tilt impacts functional cup position in total hip arthroplasty (THA). In the current study we investigated the effect of kinematic pelvic changes on cup position. In the course of a prospective controlled trial postoperative 3D-computed tomography (CT) and gait analysis before and 6 and 12 months after THA were obtained in 60 patients. Kinematic pelvic motion during gait was measured using Anybody Modeling System. By fusion with 3D-CT, the impact of kinematic pelvic tilt alterations on cup anteversion and inclination was calculated. Furthermore, risk factors correlating with high pelvic mobility were evaluated. During gait a high pelvic range of motion up to 15.6° exceeding 5° in 61.7% (37/60) of patients before THA was found. After surgery, the pelvis tilted posteriorly by a mean of 4.0 ± 6.6° (p < .001). The pelvic anteflexion led to a mean decrease of −1.9 ± 2.2° (p < .001) for cup inclination and −15.1 ± 6.1° (p < .001) for anteversion in relation to the anterior pelvic plane (APP). Kinematic pelvic changes resulted in a further change up to 2.3° for inclination and up to 12.3° for anteversion. In relation to the preoperative situation differences in postoperative cup position ranged from −4.4 to 4.6° for inclination and from −7.8 to 17.9° for anteversion, respectively. Female sex (p < .001) and normal body weight (p < .001) correlated with high alterations in pelvic tilt. Kinematic pelvic changes highly impact cup anteversion in THA. Surgeons using the APP as reference should aim for a higher anteversion of about 15° due to the functional anteflexion of the pelvis during gait. KW - component position KW - gait analysis KW - kinematics KW - pelvic tilt KW - total hip arthroplasty KW - Hüftgelenkprothese KW - Haltungsfehler KW - Hüftgelenkpfanne Y1 - 2021 U6 - https://doi.org/10.1002/jor.25106 SN - 1554-527X VL - 40 IS - 4 SP - 846 EP - 853 PB - Wiley ER -