TY - JOUR A1 - Mühling, Mischa A1 - Sandriesser, Sabrina A1 - Dendorfer, Sebastian A1 - Augat, Peter T1 - Assessment of implant internal stresses under physiological femoral loading: Translation to a simplified bending load model JF - Journal of Biomechanics N2 - The success of surgical treatment for fractures hinges on various factors, notably accurate surgical indication. The process of developing and certifying a new osteosynthesis device is a lengthy and costly process that requires multiple cycles of review and validation. Current methods, however, often rely on predecessor standards rather than physiological loads in specific anatomical locations. This study aimed to determine actual loads experienced by an osteosynthesis plate, exemplified by a standard locking plate for the femoral shaft, utilizing finite elements analysis (FEA) and to obtain the bending moments for implant development standard tests. A protocol was developed, involving the creation and validation of a fractured femur model fixed with a locking plate, mechanical testing, and FEA. The model’s validation demonstrated exceptional accuracy in predicting deformations, and the FEA revealed peak stresses in the fracture bridging zone. Results of a parametric analysis indicate that larger fracture gaps significantly impact implant mechanical behavior, potentially compromising stability. This study underscores the critical need for realistic physiological conditions in implant evaluations, providing an innovative translational approach to identify internal loads and optimize implant designs. In conclusion, this research contributes to enhancing the understanding of implant performance under physiological conditions, promoting improved designs and evaluations in fracture treatments. KW - bone biomechanics KW - finite elements analysis KW - femoral fracture KW - Euler-Bernoulli-Beam-Theory KW - simplified loading model Y1 - 2024 U6 - https://doi.org/10.1016/j.jbiomech.2024.112229 SN - 1873-2380 IS - 112229 PB - Elsevier ER - TY - GEN A1 - Marterer, Verena T1 - Simulation of the Electromagnetic Properties of Knitted Structures N2 - Designing textile Antennas is still challenging, as normal antenna design does not account for the textile nature of the materials: The e-Tex project investigates knitted and embroidered antennas to enhance the design process. The presentation shows first investigations in particular of knitted structures using measurement, simulation and theoretical models. In addition, plans to include measured models in simulation, in order to yield accurate results, will be presented. KW - Textile Antennas KW - Wearables KW - Periodic Structure Y1 - 2024 ER - TY - CHAP A1 - Rieger, Anna A1 - van de Par, Steven A1 - Rabl, Hans-Peter A1 - Oetjen, Arne T1 - Schärfeurteile für tonhaltige Geräusche und die Konsequenzen für die instrumentelle psychoakustische Analyse T2 - Fortschritte der Akustik - DAGA 2024, 50. Jahrestagung für Akustik, 18.-21. März 2024 in Hannover N2 - In einer vorrangegangenen Studie wurde der Einfluss psychoakustischer Parameter auf Präferenzurteile für konsonante und dissonante Geräusche untersucht. Diese Geräusche hatten die gleiche Lautheit und basierten auf einem festen Rauschhintergrund und eingebetteten hochfrequenten Tonkomponenten. Es zeigte sich, dass die Präferenzurteile eines Probandenkollektives durch ebenfalls erhobene Subjektivurteile zu Schärfe, Tonhaltigkeit und Dissonanz mit hoher Präzision vorhergesagt werden konnten.Durch das angewandte Versuchsdesign konnte diese rein auf Subjektivbeurteilungen bestehende Vorhersage mit einer instrumentellen Vorhersage der Präferenzurteile verglichen werden. Der Vergleich ergab einen niedrigeren Korrelationskoeffizienten für die modellbasierte Vorhersage, was auch durch die sehr niedrige Korrelation (R2<0,2) der berechneten Schärfe nach DIN45692 mit den Schärfe-Subjektivurteilen zu begründen war. Eine mögliche Erklärung der unzureichenden Prognose der Schärfeurteile könnte in der Bewertungsstrategie der Proband:innen zu finden sein. Für die getesteten Geräusche mit auffälligen tonalen Komponenten könnte statt der Schärfe des Gesamtgeräuschs nur die Schärfe des tonalen Geräuschobjekts berücksichtigt worden sein. Die Schärfe-Analyse der auf ihren tonalen Anteil reduzierten Signale zeigt eine sehr gute Übereinstimmung mit den Subjektivurteilen, was die Hypothese einer Trennung von Ton- und Rauschobjekten unterstützt. Es wird diskutiert, ob und wie das Paradigma der akustischen Objekttrennung in der Modellierung psychoakustischer Empfindungsgrößen Anwendung finden kann. Y1 - 2024 UR - https://pub.dega-akustik.de/DAGA_2024/konferenz?article=479 SN - 978-3-939296-22-5 SP - 1210 EP - 1213 PB - Deutsche Gesellschaft für Akustik e.V. (DAGA) CY - Berlin ER - TY - JOUR A1 - Maier, Robert A1 - Schlattl, Andreas A1 - Guess, Thomas A1 - Mottok, Jürgen T1 - CausalOps - Towards an industrial lifecycle for causal probabilistic graphical models JF - Information and Software Technology N2 - Context: Causal probabilistic graph-based models have gained widespread utility, enabling the modeling of cause-and-effect relationships across diverse domains. With their rising adoption in new areas, such as safety analysis of complex systems, software engineering, and machine learning, the need for an integrated lifecycle framework akin to DevOps and MLOps has emerged. Currently, such a reference for organizations interested in employing causal engineering is missing. This lack of guidance hinders the incorporation and maturation of causal methods in the context of real-life applications. Objective: This work contextualizes causal model usage across different stages and stakeholders and outlines a holistic view of creating and maintaining them within the process landscape of an organization. Method: A novel lifecycle framework for causal model development and application called CausalOps is proposed. By defining key entities, dependencies, and intermediate artifacts generated during causal engineering, a consistent vocabulary and workflow model to guide organizations in adopting causal methods are established. Results: Based on the early adoption of the discussed methodology to a real-life problem within the automotive domain, an experience report underlining the practicability and challenges of the proposed approach is discussed. Conclusion: It is concluded that besides current technical advancements in various aspects of causal engineering, an overarching lifecycle framework that integrates these methods into organizational practices is missing. Although diverse skills from adjacent disciplines are widely available, guidance on how to transfer these assets into causality-driven practices still need to be addressed in the published literature. CausalOps’ aim is to set a baseline for the adoption of causal methods in practical applications within interested organizations and the causality community. KW - Causal engineering KW - Model lifecycle KW - MLOps KW - Causal graphical models Y1 - 2024 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:898-opus4-73350 SN - 0950-5849 N1 - Corresponding author der OTH Regensburg: Robert Maier PB - Elsevier ER - TY - GEN A1 - Attenberger, Eva A1 - Conrad, Jacob A1 - Freis, Annabella A1 - Kappelmeier, Judith A1 - Strauch, Felix A1 - Pfingsten, Andrea A1 - Schedel, Valentin T1 - Die Interrater-Reliabilität von Berufsanfänger*innen bei der Bewertung von Patient*innen mit Knieproblemen beim Sit-to-Stand T2 - physioscience N2 - Hintergrund: In der Physiotherapie existieren zahlreiche Assessments zur Befunderhebung der unteren Extremität bei Kniepatient*innen. Damit können praktizierende Physiotherapeut*innen das Problem der Patient*innen genauer erfassen und dementsprechend die Behandlung aufbauen. Das Ergebnis der Beurteilung einer Patient#ast#in hängt oftmals stark von den Bewertenden ab. Fragestellung: Deshalb überprüft die Studie die Hypothese, ob innerhalb einer Tester*innengruppe mehr gleiche Ausgleichsbewegung bei der Befundung des Sit-to-Stand (STS) anhand von Videomaterial erkannt werden, als es der Standard erwarten würde. Methode: In dieser beobachtenden klinischen Querschnittsstudie wurde die Vergleichbarkeit der Befundergebnisse von 4 Therapeut*innen zum abgewandelten STS untersucht. Die zu beurteilenden Proband*innen wurden während der Durchführung des abgewandelten STS standardisiert in der Frontal- und Sagittalebene gefilmt und mittels eines Fragebogens von Berufsanfänger*innen der Physiotherapie beurteilt. Bei dem erstellten Fragebogen handelte es sich um eine systematische Abfrage aller möglichen Bewegungen der großen Gelenke der unteren Extremität mit dichotomen Antwortmöglichkeiten. Eingeschlossen wurden Proband*innen mit oder ohne diagnostizierten Knieproblemen, die älter als 18 Jahre und deutschsprachig sind. Proband*innen mit einschränkenden Nebenerkrankungen wie z.B. neurologische Erkrankungen und Operationen in den letzten 6 Monaten wurden ausgeschlossen. Anschließend wurden die Antworten der Therapeut*innen auf die Übereinstimmung der Ergebnisse überprüft. Ergebnisse: Die vollständigen Ergebnisse werden auf dem Poster nachgereicht. Die Interrater-Reliabilität wird mit Hilfe des Fleiss’ Kappa bestimmt. Voraussichtlich werden 25 Proband*innen in die Studie eingeschlossen. Schlussfolgerung: Mittels der Ergebnisse soll auf die Interrater-Reliabilität von Bewegungsbefunden des abgewandelten STS bei Kniepatient*innen geschlossen werden KW - Kniegelenk KW - Beobachtung KW - Reliabilität KW - Berufsanfänger KW - Physiotherapie KW - Inter-Rater-Reliabilität KW - Sit-to-Stand Y1 - 2023 U6 - https://doi.org/10.1055/s-00000128 VL - 20 SP - S20 (P28) PB - Thieme ER - TY - JOUR A1 - Dahmen, Victoria A1 - Weikl, Simone A1 - Bogenberger, Klaus T1 - Interpretable Machine Learning for Mode Choice Modeling on Tracking-Based Revealed Preference Data JF - Transportation Research Record: Journal of the Transportation Research Board N2 - Mode choice modeling is imperative for predicting and understanding travel behavior. For this purpose, machine learning (ML) models have increasingly been applied to stated preference and traditional self-recorded revealed preference data with promising results, particularly for extreme gradient boosting (XGBoost) and random forest (RF) models. Because of the rise in the use of tracking-based smartphone applications for recording travel behavior, we address the important and unprecedented task of testing these ML models for mode choice modeling on such data. Furthermore, as ML approaches are still criticized for leading to results that are hard to understand, we consider it essential to provide an in-depth interpretability analysis of the best-performing model. Our results show that the XGBoost and RF models far outperform a conventional multinomial logit model, both overall and for each mode. The interpretability analysis using the Shapley additive explanations approach reveals that the XGBoost model can be explained well at the overall and mode level. In addition, we demonstrate how to analyze individual predictions. Lastly, a sensitivity analysis gives insight into the relative importance of different data sources, sample size, and user involvement. We conclude that the XGBoost model performs best, while also being explainable. Insights generated by such models can be used, for instance, to predict mode choice decisions for arbitrary origin–destination pairs to see which impacts infrastructural changes would have on the mode share. KW - travel behavior KW - sensitivity analysis KW - smartphone tracking KW - mode choice KW - revealed preference KW - interpretable machine learning Y1 - 2024 U6 - https://doi.org/10.1177/03611981241246973 SN - 0361-1981 PB - SAGE Publications ER - TY - JOUR A1 - Göppel, Simon A1 - Frikel, Jürgen A1 - Haltmeier, Markus T1 - Data-Proximal Complementary ℓ1-TV Reconstruction for Limited Data Computed Tomography JF - Mathematics N2 - In a number of tomographic applications, data cannot be fully acquired, resulting in severely underdetermined image reconstruction. Conventional methods in such cases lead to reconstructions with significant artifacts. To overcome these artifacts, regularization methods are applied that incorporate additional information. An important example is TV reconstruction, which is known to be efficient in compensating for missing data and reducing reconstruction artifacts. On the other hand, tomographic data are also contaminated by noise, which poses an additional challenge. The use of a single regularizer must therefore account for both the missing data and the noise. A particular regularizer may not be ideal for both tasks. For example, the TV regularizer is a poor choice for noise reduction over multiple scales, in which case ℓ1 curvelet regularization methods are well suited. To address this issue, in this paper, we present a novel variational regularization framework that combines the advantages of different regularizers. The basic idea of our framework is to perform reconstruction in two stages. The first stage is mainly aimed at accurate reconstruction in the presence of noise, and the second stage is aimed at artifact reduction. Both reconstruction stages are connected by a data proximity condition. The proposed method is implemented and tested for limited-view CT using a combined curvelet–TV approach. We define and implement a curvelet transform adapted to the limited-view problem and illustrate the advantages of our approach in numerical experiments. KW - image reconstruction KW - limited data KW - artifact reduction KW - sparse regularization KW - total variation KW - wedge-adapted curvelets Y1 - 2024 U6 - https://doi.org/10.3390/math12101606 SN - 2227-7390 N1 - Corresponding author der OTH Regensburg: Jürgen Frikel (und Markus Haltmeier) VL - 12 IS - 10 PB - MDPI ER - TY - INPR A1 - Pangerl, Jonas A1 - Sukul, Pritam A1 - Rück, Thomas A1 - Escher, Lukas A1 - Miekisch, Wolfram A1 - Bierl, Rudolf A1 - Matysik, Frank-Michael T1 - Photoacoustic Trace-Analysis of Breath Isoprene and Acetone Via Interband- and Quantum Cascade Lasers N2 - This research presents two laser-based photoacoustic approaches for analyzing exhaled breath isoprene and acetone. The integration of a PTR-ToF-MS as a reference device ensured the reliability and accuracy of the PAS systems that is based on an ICL for isoprene and a QCL for acetone detection. The calibration yielded limits of detection of 26.9 ppbV and 1.7 ppbV, respectively, and corresponding normalized noise equivalent absorption coefficients (NNEAs) of 5.0E-9 Wcm-1Hz-0.5 and 4.9E-9 Wcm-1Hz-0.5. Laboratory as well as real breath sample measurements from alveolar breath revealed a robust system performance, with only one outlier within the static isoprene measurements. However, discrepancies emerged under dynamic breath sampling conditions, emphasizing the need for further optimization. Especially by knowing the dynamic nature and endogenous origin of exhaled isoprene our findings highlight the potential of breath analysis for non-invasive physio-metabolic and pathophysiological monitoring towards point-of-care devices. KW - photoacoustic spectroscopy KW - breath analysis/profiling KW - real-time mass spectroscopy KW - isoprene KW - acetone Y1 - 2024 U6 - https://doi.org/10.2139/ssrn.4834735 PB - Elsevier / SSRN ER - TY - GEN A1 - Horn, L. C A1 - Pippig, S. A1 - Raptis, Georgios A1 - Fischer, U. A1 - Kohler, U. A1 - Hentschel, B. A1 - Martin, R. T1 - 00083 PAI-1 AND UFA AS PARAMETERS OF TUMORASSOCIATED PROTEOLYSIS IN CERVICAL CARCINOMA T2 - International Journal of Gynecologic Cancer Y1 - 2005 U6 - https://doi.org/10.1136/ijgc-00009577-200509001-00083 SN - 1048-891X VL - 15 IS - Suppl 2 EP - 74 PB - BMJ ER - TY - CHAP A1 - Schmailzl, Marc A1 - Saffert, Anne-Sophie A1 - Karamara, Merve A1 - Linner, Thomas A1 - Eder, Friedrich Anton A1 - Hoeng, Simon Konrad A1 - Obergriesser, Mathias T1 - Enhancing Decision-Making for Human-Centered Construction Robotics: A Methodological Framework T2 - Proceedings of the 41st International Symposium on Automation and Robotics in Construction (ISARC), Lille, France N2 - While the Architecture, Engineering, and Construction (AEC) industry is increasingly aware of the rising demands for productivity and human-centered construction improvements, the holistic adoption of robotics as a fundamental strategy to address these challenges has not yet reached comprehensive fruition. This paper therefore introduces a methodological framework aiming to address the industry's pressing need for a systematic approach for assessing the feasibility of integrating robotics into human-centered construction processes. It aims to enhance decision-making regarding the degree of automation in human-centered construction processes, ranging from partial to full robotization or non-robotization. The framework is characterized by a more holistic end-to-end data-/workflow and therefore adopts a multifaceted approach, leveraging BIM-based planning methodologies and integrating new technologies [e.g., Motion Capturing (MoCap), work process simulation software incorporating Digital Human Models (DHM), self-developed conversion/interfacing software and more] that have not been widely used in the industry to date. Subsequently, the framework is evaluated in a real-life bricklaying construction process to ensure a more application-based approach. Overall, the framework advances current construction processes with a more inclusive and conscious technology infill to empower construction professionals with the workflow and corresponding tools necessary for the practical integration of robotics into human-centered construction processes. KW - Decision-Making KW - Framework KW - Workflow KW - AEC Industry KW - Robotics KW - Building Information Modeling (BIM) KW - Human-Centered KW - Motion Capturing Y1 - 2024 SN - 978-0-6458322-1-1 U6 - https://doi.org/10.22260/ISARC2024/0083 SN - 2413-5844 SP - 637 EP - 644 PB - International Association for Automation and Robotics in Construction (IAARC) ER - TY - JOUR A1 - Kral, Christian A1 - Haumer, Anton A1 - Kapeller, Hansjörg A1 - Pirker, Franz T1 - Design and Thermal Simulation of Induction Machines for Traction in Electric and Hybrid Electric Vehicles JF - World Electric Vehicle Journal N2 - An electric traction machine for an electric or a hybrid electric vehicle is usually designed for a specific operating point or cycle. For such an operating point or cycle, the masses and the cooling circuit of the electric machine determine the time dependent temperature distribution within the machine. For a specific load cycle, the thermal simulation of the machine can reveal possible mass and size reductions for a given insulation class of the machine. In addition, such simulations allow the comparison of various cooling concepts. In the machine design process, the first step is a conventional electromagnetic machine design. From the geometric data of this design and the material properties, the parameters of a thermal equivalent circuit can be derived. The differential and algebraic equations of the thermal equivalent circuit are solved by a simulation tool to predict the temperatures of the critical parts in the electric machine. A thermal equivalent circuit is accurate enough to predict the thermal behavior of the critical parts in the electric machine, and yet not too complex, to obtain simulation results with moderate numerical effort. This enables an iterative design process to optimize the drive. KW - Induction Motor KW - Electric Drive KW - Modeling KW - Simulation KW - Thermal Management Y1 - 2007 U6 - https://doi.org/10.3390/wevj1010190 SN - 2032-6653 VL - 1 IS - 1 SP - 190 EP - 196 PB - MDPI ER - TY - JOUR A1 - Jahn, Hannes A1 - Böhm, Valter A1 - Zentner, Lena T1 - Analysis of deformation in tensegrity structures with curved compressed members JF - Meccanica N2 - AbstractTensegrity structures are prestressed structures consisting of compressed members connected by prestressed tensioned members. Due to their properties, such as flexibility and lightness, mobile robots based on these structures are an attractive subject of research and are suitable for space applications. In this work, a mobile robot based on a tensegrity structure with two curved members connected by eight tensioned strings is analyzed in terms of deformation in the curved members. Further, the difference in locomotion trajectory between the undeformed and deformed structure after the prestress is analyzed. For that, the theory of large deflections of rod-like structures is used. To determine the relationship between acting forces and the deformation, the structure is optimized using minimization algorithms in Python. The results are validated by parameter studies in FEM. The analysis shows that the distance between the two curved members significantly influences the structure’s locomotion. It can be said that the deformation of the components significantly influences the locomotion of tensegrity structures and should be considered when analyzing highly compliant structures. KW - Rolling locomotion KW - Mobile robot KW - Tensegrity structures KW - Deformation of compressedmembers KW - Finite element simulations Y1 - 2024 U6 - https://doi.org/10.1007/s11012-024-01833-y SN - 0025-6455 PB - Springer Nature ER - TY - JOUR A1 - Tezel, Tugce A1 - Schultheiss, Ulrich A1 - Hornberger, Helga A1 - Kovan, Volkan T1 - Operational wear behaviour of 3D-printed lightweight metal gears: EDS and oil analysis comparison JF - Materials Testing N2 - Additive manufacturing (AM) has come to the fore in recent years among manufacturing techniques. This technique, which has different advantages than traditional ones such as casting, forging and machining, is expected to be widely used in producing machine parts like gears in the coming years. Therefore, experimental data on AM parameters for lightweight metal gears are important for industrial production. In this study, a wear test was applied to AlSi10Mg and Ti6Al4V gears under operational conditions, and the wear behaviour of conventionally and additively manufactured gears was compared. The amount of abrasion elements was determined by analysing the oil in the gearbox. In addition, gear surfaces were analysed using scanning electron microscopy and an energy-dispersive spectrometer before and after wear. Thus, the wear behaviour of gears produced by conventional and AM under service conditions was demonstrated comparatively. KW - additive manufacturing KW - titanium KW - aluminium KW - gear KW - wear Y1 - 2024 U6 - https://doi.org/10.1515/mt-2023-0222 SN - 0025-5300 VL - 66 IS - 6 SP - 830 EP - 834 PB - de Gruyter ER - TY - JOUR A1 - Auer, Simon A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Using markerless motion capture and musculoskeletal models: An evaluation of joint kinematics JF - Technology and Health Care N2 - BACKGROUND: This study presents a comprehensive comparison between a marker-based motion capture system (MMC) and a video-based motion capture system (VMC) in the context of kinematic analysis using musculoskeletal models. OBJECTIVE: Focusing on joint angles, the study aimed to evaluate the accuracy of VMC as a viable alternative for biomechanical research. METHODS: Eighteen healthy subjects performed isolated movements with 17 joint degrees of freedom, and their kinematic data were collected using both an MMC and a VMC setup. The kinematic data were entered into the AnyBody Modelling System, which enables the calculation of joint angles. The mean absolute error (MAE) was calculated to quantify the deviations between the two systems. RESULTS: The results showed good agreement between VMC and MMC at several joint angles. In particular, the shoulder, hip and knee joints showed small deviations in kinematics with MAE values of 4.8∘, 6.8∘ and 3.5∘, respectively. However, the study revealed problems in tracking hand and elbow movements, resulting in higher MAE values of 13.7∘ and 27.7∘. Deviations were also higher for head and thoracic movements. CONCLUSION: Overall, VMC showed promising results for lower body and shoulder kinematics. However, the tracking of the wrist and pelvis still needs to be refined. The research results provide a basis for further investigations that promote the fusion of VMC and musculoskeletal models. KW - biomechanics KW - range of motion KW - musculoskeletal system KW - optical motion capture Y1 - 2024 U6 - https://doi.org/10.3233/THC-240202 SN - 0928-7329 N1 - Corresponding author der OTH Regensburg: Sebastian Dendorfer SP - 1 EP - 10 PB - IOS Press ER - TY - CHAP A1 - Maiwald, Frederik A1 - Kroth, Lea A1 - Laskin, Alexander A1 - Hierl, Stefan A1 - Schmidt, Michael T1 - Enlarging the process window in absorber-free laser transmission welding of polymer foils using tailored laser intensity distribution T2 - Procedia CIRP Y1 - 2024 N1 - accepted by publisher ER - TY - RPRT A1 - Kuhn, Alexander A1 - Franzius, Jan Niklas A1 - Möller, Dennis A1 - Pralle, Norbert A1 - Reich, Franziska A1 - Hellmuth, René A1 - Tombeil, Anne-Sophie A1 - Wenzel, Günter A1 - Linner, Thomas A1 - Schmailzl, Marc T1 - Machbarkeitsstudie für den Aufbau eines Kompetenzzentrums für Baurobotik im Hochbau : Akronym: CONSAS (Construction Assistance Robotics) : innerhalb des Förderschwerpunktes des BMBF "Roboter für Assistenzfunktionen: Interaktion in der Praxis" Phase 1: Machbarkeitsstudie N2 - The overall aim of the project proposal is to develop a systematic, integrative approach for the use of assistance robotics on building construction sites, involving all stakeholders in construction robotics. Y1 - 2022 U6 - https://doi.org/10.2314/KXP:1845903056 N1 - CC BY-ND 3.0 PB - Ed. Züblin AG CY - Stuttgart ER - TY - GEN A1 - Dendorfer, Sebastian T1 - Diagnostische Genauigkeit und klinische Anwendungen tragbarer Bewegungssensoren für die Kniegelenksrehabilitation Y1 - 2024 CY - Nürnberg ER - TY - INPR A1 - Förstl, Nikolas A1 - Adler, Ina A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Technologies for Evaluation of Pelvic Floor Functionality: A Systematic Review N2 - Pelvic floor dysfunction is a common problem in women and has a negative impact ontheir quality of life. The aim of this review was to provide a general overview of the current state oftechnology used to assess pelvic floor functionality. It also provides literature research of the phys-iological and anatomical factors that correlate with pelvic floor health. The systematic review wasconducted according to the PRISMA guidelines. PubMed, ScienceDirect, Cochrane Library andIEEE databases were searched for publications on sensor technology for the assessment of pelvicfloor functionality. Anatomical and physiological parameters were identified through a manualsearch. In the systematic review 115 publications were included. 12 different sensor technologieswere identified. Information on the obtained parameters, sensor position, test activities and subjectcharacteristics were prepared in tabular form from each publication. 16 anatomical and physiologi- cal parameters influencing pelvic floor health were identified in 17 published studies and rankedfor their statistical significance. Taken together, this review could serve as a basis for the develop-ment of novel sensors which could allow for quantifiable prevention and diagnosis, as well as par-ticularized documentation of rehabilitation processes related to pelvic floor dysfunctions. KW - pelvic floor KW - sensors KW - functionality KW - influence parameters Y1 - 2024 U6 - https://doi.org/10.31219/osf.io/dcqyg N1 - Der Aufsatz wurde peer-reviewd veröffentlich und ist ebenfalls in diesem Repositorium verzeichnet unter: https://opus4.kobv.de/opus4-oth-regensburg/frontdoor/index/index/docId/7321 PB - Center for Open Science ER - TY - JOUR A1 - Förstl, Nikolas A1 - Adler, Ina A1 - Süß, Franz A1 - Dendorfer, Sebastian T1 - Technologies for Evaluation of Pelvic Floor Functionality: A Systematic Review JF - Sensors N2 - Pelvic floor dysfunction is a common problem in women and has a negative impact on their quality of life. The aim of this review was to provide a general overview of the current state of technology used to assess pelvic floor functionality. It also provides literature research of the physiological and anatomical factors that correlate with pelvic floor health. This systematic review was conducted according to the PRISMA guidelines. The PubMed, ScienceDirect, Cochrane Library, and IEEE databases were searched for publications on sensor technology for the assessment of pelvic floor functionality. Anatomical and physiological parameters were identified through a manual search. In the systematic review, 114 publications were included. Twelve different sensor technologies were identified. Information on the obtained parameters, sensor position, test activities, and subject characteristics was prepared in tabular form from each publication. A total of 16 anatomical and physiological parameters influencing pelvic floor health were identified in 17 published studies and ranked for their statistical significance. Taken together, this review could serve as a basis for the development of novel sensors which could allow for quantifiable prevention and diagnosis, as well as particularized documentation of rehabilitation processes related to pelvic floor dysfunctions. Y1 - 2024 U6 - https://doi.org/10.3390/s24124001 N1 - Die Preprint-Version ist ebenfalls in diesem Repositorium verzeichnet unter: https://opus4.kobv.de/opus4-oth-regensburg/frontdoor/index/index/docId/7306 VL - 24 IS - 12 PB - MDPI ER - TY - JOUR A1 - Wagner, Maria Stella A1 - Kranz, Michael A1 - Krenkel, Lars A1 - Pointner, Daniel A1 - Foltan, Maik A1 - Lubnow, Matthias A1 - Lehle, Karla ED - Becatti, Matteo T1 - Computer based visualization of clot structures in extracorporeal membrane oxygenation and histological clot investigations for understanding thrombosis in membrane lungs JF - Frontiers in Medicine N2 - Extracorporeal membrane oxygenation (ECMO) was established as a treatment for severe cardiac or respiratory disease. Intra-device clot formation is a common risk. This is based on complex coagulation phenomena which are not yet sufficiently understood. The objective was the development and validation of a methodology to capture the key properties of clots deposed in membrane lungs (MLs), such as clot size, distribution, burden, and composition. One end-oftherapy PLS ML was examined. Clot detection was performed using multidetector computed tomography (MDCT), microcomputed tomography (μCT), and photography of fiber mats (fiber mat imaging, FMI). Histological staining was conducted for von Willebrand factor (vWF), platelets (CD42b, CD62P), fibrin, and nucleated cells (4′, 6-diamidino-2-phenylindole, DAPI). The three imaging methods showed similar clot distribution inside the ML. Independent of the imaging method, clot loading was detected predominantly in the inlet chamber of the ML. The μCT had the highest accuracy. However, it was more expensive and time consuming than MDCT or FMI. The MDCT detected the clots with low scanning time. Due to its lower resolution, it only showed clotted areas but not the exact shape of clot structures. FMI represented the simplest variant, requiring little effort and resources. FMI allowed clot localization and calculation of clot volume. Histological evaluation indicated omnipresent immunological deposits throughout the ML. Visually clot-free areas were covered with leukocytes and platelets forming platelet-leukocyte aggregates (PLAs). Cells were embedded in vWF cobwebs, while vWF fibers were negligible. In conclusion, the presented methodology allowed adequate clot identification and histological classification of possible thrombosis markers such as PLAs. KW - ECMO KW - membrane lung KW - µCT KW - MDCT KW - shear induced clotting KW - vWF KW - histological evaluation Y1 - 2024 U6 - https://doi.org/10.3389/fmed.2024.1416319 IS - 11 PB - Frontiers ER -