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  <doc>
    <id>7702</id>
    <completedYear/>
    <publishedYear>2025</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>12</pageNumber>
    <edition/>
    <issue/>
    <volume>424</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Photoacoustic trace-analysis of breath isoprene and acetone via interband- and Quantum Cascade Lasers</title>
    <abstract language="eng">This research presents two laser-based photoacoustic approaches for analyzing exhaled breath isoprene and acetone. The integration of a PTR-ToF-MS as a reference device ensured the reliability and accuracy of the photoacoustic systems that is based on an ICL for isoprene and a QCL for acetone detection. The calibration yielded limits of detection of 26.9 ppbV and 1.7 ppbV, respectively, and corresponding normalized noise equivalent absorption coefficients (NNEAs) of 5.0E-9 Wcm 1Hz 0.5 and 4.9E-9 Wcm 1Hz 0.5. Laboratory as well as real breath sample measurements from alveolar breath revealed a robust system performance, with only one outlier within the static isoprene measurements. However, discrepancies emerged under dynamic breath sampling conditions, emphasizing the need for further optimization. Especially by knowing the dynamic nature and endogenous origin of exhaled isoprene our findings highlight the potential of breath analysis for non-invasive&#13;
physio-metabolic and pathophysiological monitoring towards point-of-care devices</abstract>
    <parentTitle language="eng">Sensors and Actuators: B. Chemical</parentTitle>
    <identifier type="doi">10.1016/j.snb.2024.136886</identifier>
    <identifier type="urn">urn:nbn:de:bvb:898-opus4-77024</identifier>
    <note>Corresponding author der OTH Regensburg: Jonas Pangerl</note>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <enrichment key="CorrespondingAuthor">Jonas Pangerl</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Jonas Pangerl</author>
    <author>Pritam Sukul</author>
    <author>Thomas Rück</author>
    <author>Lukas Escher</author>
    <author>Wolfram Miekisch</author>
    <author>Rudolf Bierl</author>
    <author>Frank-Michael Matysik</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Photoacoustic spectroscopy</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Breath analysis/profiling</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Real-time mass spectrometry</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Isoprene</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Acetone</value>
    </subject>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="oaweg" number="">Hybrid Open Access - OA-Veröffentlichung in einer Subskriptionszeitschrift/-medium</collection>
    <collection role="oaweg" number="">Corresponding author der OTH Regensburg</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
    <collection role="funding" number="">DEAL Elsevier</collection>
    <collection role="DFGFachsystematik" number="1">Ingenieurwissenschaften</collection>
    <thesisPublisher>Ostbayerische Technische Hochschule Regensburg</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-oth-regensburg/files/7702/Pangerl_Sensors_Actuators_2025.pdf</file>
  </doc>
</export-example>
