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  <doc>
    <id>404</id>
    <completedYear/>
    <publishedYear>2005</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>104</pageFirst>
    <pageLast>106</pageLast>
    <pageNumber/>
    <edition/>
    <issue>2</issue>
    <volume>273</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">CD44-v6 concentrations in carcinoma of the uterine cervix: lack of prognostic significance</title>
    <abstract language="deu">Several kinds of cellular adhesion molecules, like different splicing variants of CD 44, have gained important as prognostic or markers for metastatic disease. Fresh frozen samples from 64 cervical carcinoma (CX) were stored in liquid nitrogen and examined using ELISA-technique, testing the prognostic impact. Normal cervical tissue served as control. CD 44-v6 concentration, was significant elevated in tumor tissue, when compared to the controls (P=0.04). There was no correlation to tumor stage (P=0.61), lymphovascular space involvement (P=0.075) or pelvic lymph node involvement (P=0.81). The CD 44-v6 concentration was not informative regarding recurrence-free and overall survival. Contrary to immunohistochemistry, the quantification of CD 44-v6 using ELISA-technique does not provide any further information.</abstract>
    <parentTitle language="eng">Archives of Gynecology and Obstetrics</parentTitle>
    <identifier type="doi">10.1007/s00404-005-0039-5</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <author>Lars-Christian Horn</author>
    <author>Georgios Raptis</author>
    <author>Uta Fischer</author>
    <author>Bettina Hentschel</author>
    <author>U. Köhler</author>
    <author>Christine E. Richter</author>
    <author>Rosemarie Martin</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Gebärmutterhalskrebs</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Antigen CD44</value>
    </subject>
    <collection role="ddc" number="618">Gynäkologie, Geburtsmedizin, Pädiatrie, Geriatrie</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>368</id>
    <completedYear/>
    <publishedYear>2005</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>103</pageFirst>
    <pageLast>108</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>CSREA Press</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">An Evaluated Certification Services System for the German National Root CA - Legally Binding and Trustworthy Transactions in E-Business and E-Government</title>
    <parentTitle language="eng">Proceedings of The 2005 International Conference on E-Business, Enterprise Information Systems, E-Government, and Outsourcing, EEE 2005, Las Vegas, Nevada, USA, June 20-23, 2005</parentTitle>
    <identifier type="isbn">1-932415-76-9</identifier>
    <author>Alexander Wiesmaier</author>
    <author>Markus Lippert</author>
    <author>Vangelis Karatsiolis</author>
    <author>Georgios Raptis</author>
    <author>Johannes Buchmann</author>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16315">Information und Kommunikation</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>365</id>
    <completedYear/>
    <publishedYear>2003</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst>81</pageFirst>
    <pageLast>82</pageLast>
    <pageNumber/>
    <edition/>
    <issue>7</issue>
    <volume/>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Merkmal Iris. Können diese Augen lügen?</title>
    <parentTitle language="deu">Spektrum der Wissenschaft</parentTitle>
    <identifier type="url">https://www.spektrum.de/magazin/koennen-diese-augen-luegen/829906</identifier>
    <author>Ch. Busch</author>
    <author>H. Daum</author>
    <author>Georgios Raptis</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Biometrie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Mustererkennung</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Iris</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Regenbogenhaut</value>
    </subject>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>372</id>
    <completedYear/>
    <publishedYear>2015</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferencepresentation</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Mögliche Auswirkungen der eIDAS-Verordnung auf die Telematikinfrastruktur und die eArztausweise</title>
    <parentTitle language="deu">CAST-Workshop PKI, Darmstadt, 29.01.2015</parentTitle>
    <subTitle language="deu">Vortrag</subTitle>
    <author>Georgios Raptis</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Europäische Union &lt;eIDAS-Verordnung&gt;</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Telemedizin</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>eArztausweis</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Elektronischer Arztausweis</value>
    </subject>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>369</id>
    <completedYear/>
    <publishedYear>2004</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>192</pageNumber>
    <edition/>
    <issue/>
    <volume/>
    <type>book</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation>Bundesamt für Sicherheit in der Informationstechnik</contributingCorporation>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Sichere Client-Server-Architekturen für E-Government</title>
    <subTitle language="deu">E-Government-Handbuch</subTitle>
    <author>S. Sauer</author>
    <author>Th. Wolf</author>
    <author>M. Buch</author>
    <author>Georgios Raptis</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Client-Server-Konzept</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Datensicherheit</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>E-Government</value>
    </subject>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>389</id>
    <completedYear/>
    <publishedYear>2006</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferencepresentation</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">HPCs als Basis für den elektronischen Arztausweis</title>
    <parentTitle language="deu">Smartcard-Workshops, Fraunhofer SIT, 07.02.2006</parentTitle>
    <subTitle language="deu">Vortrag</subTitle>
    <author>Georgios Raptis</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Arzt</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Ausweis</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Hochleistungsrechnen</value>
    </subject>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>370</id>
    <completedYear/>
    <publishedYear>2004</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>bachelorthesis</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation>TU Darmstadt</contributingCorporation>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Klassifikation, Anwendungen und Sicherheitskonzept von Trustcentern</title>
    <author>Georgios Raptis</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Trust Center</value>
    </subject>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>371</id>
    <completedYear/>
    <publishedYear>2015</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferencepresentation</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Datenschutzfragen zur Telemedizin</title>
    <parentTitle language="deu">Fachtagung Datenschutz in der Medizin - Update 2015 I, Hamburg 03.02.2015</parentTitle>
    <subTitle language="deu">Vortrag</subTitle>
    <author>Georgios Raptis</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Telemedizin</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Datenschutz</value>
    </subject>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>367</id>
    <completedYear/>
    <publishedYear>2008</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst>55</pageFirst>
    <pageLast>62</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>1</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Kryptographischer Langzeitschutz</title>
    <parentTitle language="deu">KES - The Information Security Journal</parentTitle>
    <author>Georgios Raptis</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Kryptologie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Datensicherung</value>
    </subject>
    <collection role="ddc" number="61">Medizin und Gesundheit</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>373</id>
    <completedYear/>
    <publishedYear>2014</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst>82</pageFirst>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>11</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Computer können Ärzte nicht ersetzen</title>
    <parentTitle language="deu">Technology Review</parentTitle>
    <subTitle language="deu">Interview</subTitle>
    <author>Georgios Raptis</author>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>405</id>
    <completedYear/>
    <publishedYear>2006</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>906</pageFirst>
    <pageLast>911</pageLast>
    <pageNumber/>
    <edition/>
    <issue>3</issue>
    <volume>103</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Pattern of invasion is of prognostic value in surgically treated cervical cancer patients</title>
    <abstract language="eng">Objectives: Different patterns of invasion (representing different grades of tumor cell dissociation) are associated with prognostic outcome in cancer. We evaluated the prognostic value of different patterns of invasion (PI) in cervical carcinomas (CX).&#13;
&#13;
Methods: Six hundred eleven surgically treated CX (FIGO IB to IIB) were re-evaluated histologically regarding the PI, using a three-level scoring system. Closed PI was defined as cohesive growth with well-delineated (pushing) borders. In finger-like PI the tumor grows in solid cords/trabecles. Highly dissociative growth in small groups or single cells was defined as spray-like PI. Types of PI were correlated to tumor stage, histo-morphologic factors and prognostic outcome.&#13;
&#13;
Results: Sixty percent of the tumors showed a spray-like PI, 30% a finger-like PI and only 7.4% were of the closed type. Spray-like PI showed a significant correlation with advanced stage disease, lymphovascular space involvement, poorly differentiated tumors and pelvic lymph node metastases. Spray-like PI was accompanied by a reduced 5-year overall survival when compared to the finger-like and closed PI (68.7% vs. 80.9% vs. 88.5%; P=0.0004). The prognostic impact of the PI disappeared in node-positive patients (P=0.06) but persisted in patients without pelvic lymph node disease (P=0.03). In multivariate analysis, using COX regression model, the PI represented as independent prognostic factor.&#13;
&#13;
Conclusions: Spray-like PI (i.e., highest degree of tumor cell dissociation) is associated with advanced tumor stages, increased rate of recurrency and a reduced overall survival. In separate analysis of patients with and without lymph node metastases, the impact of PI persisted only in node-negative cases as a prognostic factor.</abstract>
    <parentTitle language="eng">Gynecologic Oncology</parentTitle>
    <identifier type="doi">10.1016/j.ygyno.2006.05.046</identifier>
    <author>Lars-Christian Horn</author>
    <author>Uta Fischer</author>
    <author>Georgios Raptis</author>
    <author>Karin Bilek</author>
    <author>Bettina Hentschel</author>
    <author>Christine E. Richter</author>
    <author>Ulf Dietrich Braumann</author>
    <author>Jens Einenkel</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Gebärmutterhalskrebs</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Chirurgie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Metastase</value>
    </subject>
    <collection role="ddc" number="618">Gynäkologie, Geburtsmedizin, Pädiatrie, Geriatrie</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>406</id>
    <completedYear/>
    <publishedYear>2007</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>310</pageFirst>
    <pageLast>315</pageLast>
    <pageNumber/>
    <edition/>
    <issue>2</issue>
    <volume>107</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Tumor size is of prognostic value in surgically treated FIGO stage II cervical cancer</title>
    <abstract language="deu">Objectives&#13;
Tumor size is a well recognized prognostic factor in early stage cervical carcinoma (CX). However, limited knowledge exists about the value of tumor size in surgically treated CX with extrauterine extension.&#13;
&#13;
Methods&#13;
245 cases of local advanced CX (FIGO stage IIA and IIB) who received upfront surgery were evaluated regarding tumor size, regarding the prediction of pelvic lymph node involvement and recurrence free and overall survival during a median follow-up time of 54 months (95% CI 45.4–62.6 months). Tumors larger than 4 cm were defined as bulky stage disease.&#13;
&#13;
Results&#13;
Bulky disease was seen in 46.1% (113/245). 60.2% of these patients showed pelvic lymph node involvement, compared to 42.4% (56/132) in non-bulky tumors (p = 0.006; odds ratio: 2.2 [95% CI: 1.3–3.6]). Patients with bulky tumors showed an increase of recurrent disease (40.2% vs. 28.0%; p = 0.045). The relative risk for recurrent disease was 1.97 (95% CI: 1.3–3.0). The 5-year overall survival rate was significantly lower (67.7% [95% CI: 58.2–74.8] vs. 49.5% [95% CI: 36.8–59.1]; p = 0.0015). In multivariate analysis, tumor stage, pelvic lymph node involvement and maximal tumor size were independent prognostic factors.&#13;
&#13;
Conclusions&#13;
The results suggest that tumor size, defining bulky disease as tumors larger than 4 cm, is of prognostic impact also in FIGO stage II cervical carcinomas. A revised FIGO/TNM classification system similar to the subgrouping of stage IB CX is recommended for stage II using a cut-off value of 4 cm as discriminator: stage IIA1 and stage IIB1 for tumors with ≤ 4 cm and IIA2 and IIB2 for tumors &gt; 4 cm (i.e. bulky disease).</abstract>
    <parentTitle language="eng">Gynecologic Oncology</parentTitle>
    <identifier type="doi">10.1016/j.ygyno.2007.06.026</identifier>
    <author>Lars-Christian Horn</author>
    <author>Uta Fischer</author>
    <author>Georgios Raptis</author>
    <author>Karin Bilek</author>
    <author>Bettina Hentschel</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Gebärmutterhalskrebs</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Chirurgie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Tumorwachstum</value>
    </subject>
    <collection role="ddc" number="618">Gynäkologie, Geburtsmedizin, Pädiatrie, Geriatrie</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>409</id>
    <completedYear/>
    <publishedYear>2000</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Applications of the Erbium: YAG Laser in Ophthalmology - Cataracta-, Glaukoma-, Eyelid-Surgery and pars plana Vitrectomy</title>
    <abstract language="deu">Recent developments in lasers have provided us the possibility of laser ocular surgery. The xenon, argon, neodymium:YAG and dye lasers have been successfully used in out-patient clinics. The excimer laser has been attracting researchers' interest in the new application of laser to cornea and lens. The erbium:YAG laser emits a 2.94-microns beam that can ablate the transparent ocular tissues such as lenses and corneas. The author has applied this laser to the cornea, lens, vitreous and other ocular tissues. The erbium:YAG laser beam was directed through a 1.5-meter-long, 200-microns-diameter fiberoptic guide. The radiant energy measured about 50 mJ at the end of the probe. The laser was emitted as a 400-microsecond pulse. Freshly enucleated rabbit eyes were used in this study. Laser burns were applied to the tissue surface at various energy settings. At minimal power, the tissues were coagulated by the erbium:YAG laser application. At a power of more than 636-954 mJ/mm2, tissue began to evaporate; the tissue loss was observed under a surgical light microscope. Corneal photoablation, lens ablation, iridotomy, trabeculotomy, cutting of the vitreous and retinal ablation were easily performed. Like the excimer laser, the erbium:YAG laser is a potential tool for ocular surgery.</abstract>
    <subTitle language="eng">Symposium on Cataract, IOL, and Refractive Surgery. Boston, 20.05.2000 und 22.05.2000</subTitle>
    <author>H. Höh</author>
    <author>Georgios Raptis</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Augenchirurgie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>YAG-Laser</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Erbium-Laser</value>
    </subject>
    <collection role="ddc" number="617">Chirurgie und verwandte medizinische Fachrichtungen</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>410</id>
    <completedYear/>
    <publishedYear>2000</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Rolle der quantitativen CMV-DNA-Bestimmungen in der Diagnostik und Therapie der Cytomegalovirusinfektion bei immunsupprimierten Patienten</title>
    <parentTitle language="deu">Jahrestagung der Gesellschaft für Virologie in Wien, April 2000</parentTitle>
    <subTitle language="deu">Vortrag</subTitle>
    <author>I. Chaloupka</author>
    <author>Georgios Raptis</author>
    <author>A. Zach</author>
    <author>K. Brändlin</author>
    <author>H. Meier-Ewert</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Cytomegalie-Virus</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Immunsuppresion</value>
    </subject>
    <collection role="ddc" number="616">Krankheiten</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>407</id>
    <completedYear/>
    <publishedYear>2003</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Tumorassoziierte Proteolyse beim Zervixkarzinom</title>
    <parentTitle language="deu">87. Tagung der Deutschen Gesellschaft für Pathologie, 14. Juni 2003</parentTitle>
    <subTitle language="deu">Vortrag</subTitle>
    <author>Lars-Christian Horn</author>
    <author>S. Pippig</author>
    <author>Georgios Raptis</author>
    <author>Uta Fischer</author>
    <author>U. Köhler</author>
    <author>Bettina Hentschel</author>
    <author>Rosemarie Martin</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Gebärmutterhalskrebs</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Chirurgie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Tumorassoziierte Proteolyse</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Immuncytochemie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Zelladhäsion</value>
    </subject>
    <collection role="ddc" number="618">Gynäkologie, Geburtsmedizin, Pädiatrie, Geriatrie</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>408</id>
    <completedYear/>
    <publishedYear>2002</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferencepresentation</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Familiäres Zervixkarzinom – Erste Ergebnisse</title>
    <parentTitle language="deu">54. Kongress der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe</parentTitle>
    <subTitle language="deu">Poster</subTitle>
    <author>Lars-Christian Horn</author>
    <author>Georgios Raptis</author>
    <author>Uta Fischer</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Gebärmutterhalskrebs</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Familienanamnese</value>
    </subject>
    <collection role="ddc" number="61">Medizin und Gesundheit</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>375</id>
    <completedYear/>
    <publishedYear>2014</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferencepresentation</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Übersicht über die neuen Technischen Richtlinien des BSI zum ersetzenden Scannen und zur Langzeitarchivierung</title>
    <parentTitle language="deu">Telemed 2014, Berlin, 14.10.2014</parentTitle>
    <subTitle language="deu">Vortrag</subTitle>
    <author>Georgios Raptis</author>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>374</id>
    <completedYear/>
    <publishedYear>2014</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferencepresentation</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Die elektronische Gesundheitskarte</title>
    <parentTitle language="deu">7. Kommunikationsforum "Industry meets Medicine", Olpe, 5.11.2014</parentTitle>
    <subTitle language="deu">Vortrag</subTitle>
    <author>Georgios Raptis</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Elektronische Gesundheitskarte</value>
    </subject>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>2111</id>
    <completedYear/>
    <publishedYear>2021</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1</pageFirst>
    <pageLast>4</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>IEEE</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Conceptual Design and Analysis of a Mobile Digital Identity for eHealth Applications</title>
    <abstract language="eng">As mobile technology continues to improve, more and more professional services are being offered as mobile apps. This paradigm shift also affects eHealth applications. Digital identities in nation-wide eHealth infrastructures are often realized via smart cards, which however, do not support mobile applications well. In this paper we propose a concept of a mobile eID for eHealth based on smartphones with embedded secure hardware, an mobile authenticator app and an account manager as well as an Identity Provider (IdP) as backend services. The practical applicability of the concept is shown using the example of the German eHealth infrastructure. Our method generates a cryptographic key pair in secure hardware on the user’s smartphone, registers it on the IdP and uses it to authenticate on the IdP. The security of the private key and the integrity of the smartphone is also validated and attestated. The user’s established smartcard-based identity "Electronic Health Card" (EHC) forms the trust anchor. To authenticate against specialist eHealth apps the IdP issues standard-compliant OAuth2.0/OIDC tokens with a limited period of validity. Furthermore, in our security analysis we demonstrate that based on specific security requirements for smartphones and operating systems, at least the eIDAS security level "substantial" related to the technical security aspects of the system can be achieved. On the basis of this research German legislation was adjusted and "digital identities" supplementary to the smartcard-based EHC will be issued from 2023 in the German eHealth infrastructure.</abstract>
    <parentTitle language="eng">2021 IEEE EMBS International Conference on Biomedical and Health Informatics (BHI): 27-30 July 2021, Athens, Greece</parentTitle>
    <identifier type="doi">10.1109/BHI50953.2021.9508554</identifier>
    <identifier type="issn">2641-3604</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Dominik Spychalski</author>
    <author>Olaf Rode</author>
    <author>Markus Ritthaler</author>
    <author>Georgios Raptis</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>digital identity</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>mobile security</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>eHealth</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>authentication scheme</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>identity management</value>
    </subject>
    <collection role="ddc" number="000">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="ddc" number="610">Medizin und Gesundheit</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>377</id>
    <completedYear/>
    <publishedYear>2014</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferencepresentation</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Vernetzung und ubiquitäre Informationsverarbeitung – technisch-organisatorischer Datenschutz in der Arztpraxis</title>
    <parentTitle language="deu">2. Fachtagung der Gesellschaft für Datenschutz und Datensicherheit e.V. (GDD), Berlin, 13.05.2014, zertifiziert von der Ärztekammer Berlin</parentTitle>
    <subTitle language="deu">Vortrag in der 2. Fachtagung der Gesellschaft für Datenschutz und Datensicherheit e.V. (GDD), Berlin, 13.05.2014, zertifiziert von der Ärztekammer Berlin</subTitle>
    <author>Georgios Raptis</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Arztpraxis</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Datenschutz</value>
    </subject>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
  <doc>
    <id>378</id>
    <completedYear/>
    <publishedYear>2014</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferencepresentation</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Sichere Gesundheitsdaten in der Cloud? Technische Voraussetzungen und Regelungen</title>
    <parentTitle language="deu">8. Rhein-Main Zukunftskongress Krankenhaus &amp; Partner 2014, Offenbach, 21.2.2014</parentTitle>
    <subTitle language="deu">Vortrag</subTitle>
    <author>Georgios Raptis</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Cloud Computing</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Gesundheitsinformationssystem</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Datenschutz</value>
    </subject>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="raptisehealth">Raptis, Georgios (Prof. Dr.) - eHealth Lab</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
    <collection role="institutes" number="">Labor eHealth (eH)</collection>
  </doc>
</export-example>
