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  <doc>
    <id>3050</id>
    <completedYear/>
    <publishedYear>2023</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1597</pageFirst>
    <pageLast>1616</pageLast>
    <pageNumber/>
    <edition/>
    <issue>4</issue>
    <volume>39</volume>
    <type>article</type>
    <publisherName>Springer Nature</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2022-03-08</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Learning the shape of female breasts: an open-access 3D statistical shape model of the female breast built from 110 breast scans</title>
    <abstract language="eng">We present the Regensburg Breast Shape Model (RBSM)—a 3D statistical shape model of the female breast built from 110 breast scans acquired in a standing position, and the first publicly available. Together with the model, a fully automated, pairwise surface registration pipeline used to establish dense correspondence among 3D breast scans is introduced. Our method is computationally efficient and requires only four landmarks to guide the registration process. A major challenge when modeling female breasts from surface-only 3D breast scans is the non-separability of breast and thorax. In order to weaken the strong coupling between breast and surrounding areas, we propose to minimize the variance outside the breast region as much as possible. To achieve this goal, a novel concept called breast probability masks (BPMs) is introduced. A BPM assigns probabilities to each point of a 3D breast scan, telling how likely it is that a particular point belongs to the breast area. During registration, we use BPMs to align the template to the target as accurately as possible inside the breast region and only roughly outside. This simple yet effective strategy significantly reduces the unwanted variance outside the breast region, leading to better statistical shape models in which breast shapes are quite well decoupled from the thorax. The RBSM is thus able to produce a variety of different breast shapes as independently as possible from the shape of the thorax. Our systematic experimental evaluation reveals a generalization ability of 0.17 mm and a specificity of 2.8 mm. To underline the expressiveness of the proposed model, we finally demonstrate in two showcase applications how the RBSM can be used for surgical outcome simulation and the prediction of a missing breast from the remaining one. Our model is available at https://www.rbsm.re-mic.de/.</abstract>
    <parentTitle language="eng">The Visual Computer</parentTitle>
    <identifier type="doi">10.1007/s00371-022-02431-3</identifier>
    <identifier type="urn">urn:nbn:de:bvb:898-opus4-30506</identifier>
    <note>Corresponding author: Christoph Palm</note>
    <note>Zugehörige arXiv-Publikation:&#13;
https://opus4.kobv.de/opus4-oth-regensburg/frontdoor/index/index/docId/2023</note>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Maximilian Weiherer</author>
    <author>Andreas Eigenberger</author>
    <author>Bernhard Egger</author>
    <author>Vanessa Brébant</author>
    <author>Lukas Prantl</author>
    <author>Christoph Palm</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Statistical shape model</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Non-rigid surface registration</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Breast imaging</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Surgical outcome simulation</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Breast reconstruction surgery</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="ddc" number="6">Technik, Medizin, angewandte Wissenschaften</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCBE">Regensburg Center of Biomedical Engineering - RCBE</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="oaweg" number="">Hybrid Open Access - OA-Veröffentlichung in einer Subskriptionszeitschrift/-medium</collection>
    <collection role="oaweg" number="">Corresponding author der OTH Regensburg</collection>
    <collection role="funding" number="">DEAL Springer Nature</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
    <thesisPublisher>Ostbayerische Technische Hochschule Regensburg</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-oth-regensburg/files/3050/Weiherer_et_al-2022-The_Visual_Computer.pdf</file>
  </doc>
  <doc>
    <id>3240</id>
    <completedYear/>
    <publishedYear>2022</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>2228</pageFirst>
    <pageLast>2236</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>46</volume>
    <type>article</type>
    <publisherName>Springer Nature</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2022-03-17</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Implants Versus Lipograft: Analysis of Long-Term Results Following Congenital Breast Asymmetry Correction</title>
    <abstract language="eng">Aims&#13;
Congenital breast asymmetry represents a particular challenge to the classic techniques of plastic surgery given the young age of patients at presentation. This study reviews and compares the long-term results of traditional breast augmentation using silicone implants and the more innovative technique of lipografting. &#13;
&#13;
Methods&#13;
To achieve this, we not only captured subjective parameters such as satisfaction with outcome and symmetry, but also objective parameters including breast vol-ume and anthropometric measurements. The objective examination was performed manually and by using the Vectra H2 photogrammetry scanning system.&#13;
&#13;
Results&#13;
Differences between patients undergoing either implant augmentation or lipograft were revealed not to be significant with respect to patient satisfaction with surgical outcome (p= 0.55) and symmetry (p= 0.69). Furthermore, a breast symmetry of 93 % was reported in both groups. Likewise, no statistically significant volume difference between the left and right breasts was observed in both groups (p\0.41). However, lipograft patients needed on average 2.9 procedures to achieve the desired result, compared with 1.3 for implant augmentation. In contrast, patients treated with implant augmentation may require anumber of implant changes during their lifetime.&#13;
&#13;
Conclusion&#13;
Both methods may be considered for patients presenting with congenital breast asymmetry.</abstract>
    <parentTitle language="eng">Aesthetic Plastic Surgery</parentTitle>
    <identifier type="doi">10.1007/s00266-022-02843-5</identifier>
    <identifier type="urn">urn:nbn:de:bvb:898-opus4-32404</identifier>
    <note>Corresponding author der OTH Regensburg: Vanessa Brébant</note>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="CorrespondingAuthor">Vanessa Brébant</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Vanessa Brébant</author>
    <author>Maximilian Weiherer</author>
    <author>Vivien Noisser</author>
    <author>Stephan Seitz</author>
    <author>Lukas Prantl</author>
    <author>Andreas Eigenberger</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Congenital Breast Asymmetry</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>3D volumetry</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Autologous fat injections</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Three-dimensional imaging</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Lipograft</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="ddc" number="6">Technik, Medizin, angewandte Wissenschaften</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="oaweg" number="">Hybrid Open Access - OA-Veröffentlichung in einer Subskriptionszeitschrift/-medium</collection>
    <collection role="oaweg" number="">Corresponding author der OTH Regensburg</collection>
    <collection role="funding" number="">DEAL Springer Nature</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
    <collection role="institutes" number="">Labor Biomechanik (LBM)</collection>
    <thesisPublisher>Ostbayerische Technische Hochschule Regensburg</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-oth-regensburg/files/3240/Br-bant_et_al-2022-Aesthetic_Plastic_Surgery.pdf</file>
  </doc>
  <doc>
    <id>97</id>
    <completedYear/>
    <publishedYear>2019</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>30</pageFirst>
    <pageLast>42</pageLast>
    <pageNumber/>
    <edition/>
    <issue>1</issue>
    <volume>9</volume>
    <type>article</type>
    <publisherName>AME Publishing Company</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Imitating human soft tissue on basis of a dual-material 3D print using a support-filled metamaterial to provide bimanual haptic for a hand surgery training system</title>
    <abstract language="eng">Background: Currently, it is common practice to use three-dimensional (3D) printers not only for rapid prototyping in the industry, but also in the medical area to create medical applications for training inexperienced surgeons. In a clinical training simulator for minimally invasive bone drilling to fix hand fractures with Kirschner-wires (K-wires), a 3D-printed hand phantom must not only be geometrically but also haptically correct. Due to a limited view during an operation, surgeons need to perfectly localize underlying risk structures only by feeling of specific bony protrusions of the human hand.&#13;
Methods: The goal of this experiment is to imitate human soft tissue with its haptic and elasticity for a realistic hand phantom fabrication, using only a dual-material 3D printer and support-material-filled metamaterial between skin and bone. We present our workflow to generate lattice structures between hard bone and soft skin with iterative cube edge (CE) or cube face (CF) unit cells. Cuboid and finger shaped sample prints with and without inner hard bone in different lattice thickness are constructed and 3D printed.&#13;
Results: The most elastic available rubber-like material is too firm to imitate soft tissue. By reducing the amount of rubber in the inner volume through support material (SUP), objects become significantly softer. Without metamaterial, after disintegration, the SUP can be shifted through the volume and thus the body loses its original shape. Although the CE design increases the elasticity, it cannot restore the fabric form. In contrast to CE, the CF design increases not only the elasticity but also guarantees a local limitation of the SUP. Therefore, the body retains its shape and internal bones remain in its intended place. Various unit cell sizes, lattice thickening and skin thickness regulate the rubber material and SUP ratio. Test prints with higher SUP and lower rubber material percentage appear softer and vice versa. This was confirmed by an expert surgeon evaluation. Subjects adjudged pure rubber-like material as too firm and samples only filled with SUP or lattice structure in CE design as not suitable for imitating tissue. 3D-printed finger samples in CF design were rated as realistic compared to the haptic of human tissue with a good palpable bone structure.&#13;
Conclusions: We developed a new dual-material 3D print technique to imitate soft tissue of the human hand with its haptic properties. Blowy SUP is trapped within a lattice structure to soften rubber-like 3D print material, which makes it possible to reproduce a realistic replica of human hand soft tissue.</abstract>
    <parentTitle language="eng">Quantitative Imaging in Medicine and Surgery</parentTitle>
    <identifier type="doi">10.21037/qims.2018.09.17</identifier>
    <identifier type="urn">urn:nbn:de:bvb:898-opus4-979</identifier>
    <note>Corresponding author: Christoph Palm</note>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Creative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International</licence>
    <author>Johannes Maier</author>
    <author>Maximilian Weiherer</author>
    <author>Michaela Huber</author>
    <author>Christoph Palm</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Dual-material 3D printing</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Hand surgery training</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Metamaterial</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Support material</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Tissue-imitating hand phantom</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Handchirurgie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>3D-Druck</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Biomaterial</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Lernprogramm</value>
    </subject>
    <collection role="ddc" number="6">Technik, Medizin, angewandte Wissenschaften</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCBE">Regensburg Center of Biomedical Engineering - RCBE</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="oaweg" number="">Gold Open Access- Erstveröffentlichung in einem/als Open-Access-Medium</collection>
    <collection role="persons" number="palmhaptivist">Palm, Christoph (Prof. Dr.) - Projekt HaptiVisT</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="oaweg" number="">Corresponding author der OTH Regensburg</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>346</id>
    <completedYear/>
    <publishedYear>2020</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>340</pageFirst>
    <pageLast>455</pageLast>
    <pageNumber/>
    <edition/>
    <issue>02</issue>
    <volume>10</volume>
    <type>article</type>
    <publisherName>AME Publishing Company</publisherName>
    <publisherPlace>Hong Kong, China</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2020-04-22</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Optically tracked and 3D printed haptic phantom hand for surgical training system</title>
    <abstract language="eng">Background: For surgical fixation of bone fractures of the human hand, so-called Kirschner-wires (K-wires) are drilled through bone fragments. Due to the minimally invasive drilling procedures without a view of risk structures like vessels and nerves, a thorough training of young surgeons is necessary. For the development of a virtual reality (VR) based training system, a three-dimensional (3D) printed phantom hand is required. To ensure an intuitive operation, this phantom hand has to be realistic in both, its position relative to the driller as well as in its haptic features. The softest 3D printing material available on the market, however, is too hard to imitate human soft tissue. Therefore, a support-material (SUP) filled metamaterial is used to soften the raw material. Realistic haptic features are important to palpate protrusions of the bone to determine the drilling starting point and angle. An optical real-time tracking is used to transfer position and rotation to the training system.&#13;
Methods: A metamaterial already developed in previous work is further improved by use of a new unit cell. Thus, the amount of SUP within the volume can be increased and the tissue is softened further. In addition, the human anatomy is transferred to the entire hand model. A subcutaneous fat layer and penetration of air through pores into the volume simulate shiftability of skin layers. For optical tracking, a rotationally symmetrical marker attached to the phantom hand with corresponding reference marker is developed. In order to ensure trouble-free position transmission, various types of marker point applications are tested.&#13;
&#13;
Results: Several cuboid and forearm sample prints lead to a final 30 centimeter long hand model. The whole haptic phantom could be printed faultless within about 17 hours. The metamaterial consisting of the new unit cell results in an increased SUP share of 4.32%. Validated by an expert surgeon study, this allows in combination with a displacement of the uppermost skin layer a good palpability of the bones. Tracking of the hand marker in dodecahedron design works trouble-free in conjunction with a reference marker attached to the worktop of the training system.&#13;
&#13;
Conclusions: In this work, an optically tracked and haptically correct phantom hand was developed using dual-material 3D printing, which can be easily integrated into a surgical training system.</abstract>
    <parentTitle language="eng">Quantitative Imaging in Medicine and Surgery</parentTitle>
    <identifier type="doi">10.21037/qims.2019.12.03</identifier>
    <note>Corresponding author: Christoph Palm</note>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Creative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International</licence>
    <author>Johannes Maier</author>
    <author>Maximilian Weiherer</author>
    <author>Michaela Huber</author>
    <author>Christoph Palm</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Handchirurgie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>3D-Druck</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Lernprogramm</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Zielverfolgung</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>HaptiVisT</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Dual-material 3D printing</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>hand surgery training</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>metamaterial</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>tissue imitating phantom hand</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="ddc" number="6">Technik, Medizin, angewandte Wissenschaften</collection>
    <collection role="ddc" number="617">Chirurgie und verwandte medizinische Fachrichtungen</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCBE">Regensburg Center of Biomedical Engineering - RCBE</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="oaweg" number="">Gold Open Access- Erstveröffentlichung in einem/als Open-Access-Medium</collection>
    <collection role="persons" number="palmhaptivist">Palm, Christoph (Prof. Dr.) - Projekt HaptiVisT</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="oaweg" number="">Corresponding author der OTH Regensburg</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>6</id>
    <completedYear/>
    <publishedYear>2019</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1143</pageFirst>
    <pageLast>1145</pageLast>
    <pageNumber>3</pageNumber>
    <edition/>
    <issue>7</issue>
    <volume>68</volume>
    <type>article</type>
    <publisherName>British Society of Gastroenterology</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2018-12-03</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Computer-aided diagnosis using deep learning in the evaluation of early oesophageal adenocarcinoma</title>
    <abstract language="eng">Computer-aided diagnosis using deep learning (CAD-DL) may be an instrument to improve endoscopic assessment of Barrett’s oesophagus&#13;
(BE) and early oesophageal adenocarcinoma (EAC). Based on still images from two databases, the diagnosis of EAC by CAD-DL reached sensitivities/specificities of 97%/88% (Augsburg data) and 92%/100% (Medical Image Computing and Computer-Assisted Intervention [MICCAI]&#13;
data) for white light (WL) images and 94%/80% for narrow band images (NBI) (Augsburg data), respectively. Tumour margins delineated by&#13;
experts into images were detected satisfactorily with a Dice coefficient (D) of 0.72. This could be a first step towards CAD-DL for BE assessment. If developed further, it could become a useful&#13;
adjunctive tool for patient management.</abstract>
    <parentTitle language="eng">GuT</parentTitle>
    <identifier type="doi">10.1136/gutjnl-2018-317573</identifier>
    <identifier type="urn">urn:nbn:de:bvb:898-opus4-68</identifier>
    <note>Corresponding authors: Alanna Ebigbo and Christoph Palm</note>
    <enrichment key="opus.import.file">1</enrichment>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Creative Commons - CC BY-NC - Namensnennung - Nicht kommerziell 4.0 International</licence>
    <author>Alanna Ebigbo</author>
    <author>Robert Mendel</author>
    <author>Andreas Probst</author>
    <author>Johannes Manzeneder</author>
    <author>Luis Antonio de Souza Jr.</author>
    <author>João Paulo Papa</author>
    <author>Christoph Palm</author>
    <author>Helmut Messmann</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Speiseröhrenkrebs</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Computerunterstütztes Verfahren</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Lernen</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCHST">Regensburg Center of Health Sciences and Technology - RCHST</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="oaweg" number="">Hybrid Open Access - OA-Veröffentlichung in einer Subskriptionszeitschrift/-medium</collection>
    <collection role="oaweg" number="">Corresponding author der OTH Regensburg</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
    <thesisPublisher>Ostbayerische Technische Hochschule Regensburg</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-oth-regensburg/files/6/gutjnl_2018_ebigbo.pdf</file>
  </doc>
  <doc>
    <id>8515</id>
    <completedYear/>
    <publishedYear>2025</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>31</pageNumber>
    <edition/>
    <issue/>
    <volume>12</volume>
    <type>article</type>
    <publisherName>Springer</publisherName>
    <publisherPlace>Heidelberg</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Stacking the odds: full-stack quantum system design space exploration</title>
    <abstract language="deu">Design space exploration (DSE) plays an important role in optimising quantum circuit execution by systematically evaluating different configurations of compilation strategies and hardware settings. In this paper, we conduct a comprehensive investigation into the impact of various layout methods, qubit routing techniques, and optimisation levels, as well as device-specific properties such as different variants and strengths of noise and imperfections, the topological structure of qubits, connectivity densities, and back-end sizes. By spanning through these dimensions, we aim to understand the interplay between compilation choices and hardware characteristics. A key question driving our exploration is whether the optimal selection of device parameters, mapping techniques, comprising of initial layout strategies and routing heuristics can mitigate device induced errors beyond standard error mitigation approaches. Our results show that carefully selecting software strategies (e.g., mapping and routing algorithms) and tailoring hardware characteristics (such as minimising noise and leveraging topology and connectivity density) significantly improve the fidelity of circuit execution outcomes, and thus the expected correctness or success probability of the computational result. We provide estimates based on key metrics such as circuit depth, gate count and expected fidelity. Our results highlight the importance of hardware–software co-design, particularly as quantum systems scale to larger dimensions, and along the way towards fully error corrected quantum systems: Our study is based on computationally noisy simulations, but considers various implementations of quantum error correction (QEC) using the same approach as for other algorithms. The observed sensitivity of circuit fidelity to noise and connectivity suggests that co-design principles will be equally critical when integrating QEC in future systems. Our exploration provides practical guidelines for co-optimising physical mapping, qubit routing, and hardware configurations in realistic quantum computing scenarios.</abstract>
    <parentTitle language="deu">EPJ Quantum Technology</parentTitle>
    <identifier type="doi">10.1140/epjqt/s40507-025-00413-7</identifier>
    <identifier type="urn">urn:nbn:de:bvb:898-opus4-85157</identifier>
    <note>Corresponding author der OTH Regensburg: Hila Safi</note>
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    <author>Hila Safi</author>
    <author>Medina Bandic</author>
    <author>Christoph Niedermeier</author>
    <author>Carmen G. Almudever</author>
    <author>Sebastian Feld</author>
    <author>Wolfgang Mauerer</author>
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    <thesisYearAccepted/>
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    <pageNumber>12</pageNumber>
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    <title language="eng">A heuristic packet processing model for improved encrypted network analysis</title>
    <abstract language="eng">Modern networked systems, such as those in the automotive sector, face increasing complexity and growing attack surfaces due to the rise of interconnected and data-driven technologies. Detecting malicious behavior in these environments requires efficient and scalable methods that can operate reliably despite limited resources and high communication volumes. This paper proposes a heuristic packet processing model designed to support intrusion detection based on structural and temporal characteristics of encrypted network traffic. The model follows a modular architecture consisting of four key phases: recording, sorting, prioritizing, and analyzing. At the core of the approach is the Polymetric Queueing Topology Space, a feature space that combines statistical and time series attributes derived from model structure and flow data. These features serve as input for machine learning models, which can effectively distinguish between benign and intrusion traffic patterns without relying on packet data beyond the transport layer. The approach was evaluated using the publicly available ToN_IoT dataset and demonstrated that reliable classification is achievable using a subset of the developed feature space that contains model-derived traffic features. We used Random Forest for supervised binary and multi-class classification achieving high accuracy scores of 99% for binary and 98% for multi-class classification. Additionally, for unsupervised anomaly detection, we created an Isolation Forest model accomplishing F1-scores of 0.92 for the benign and 0.96 for intrusion class. The architecture is designed to enable dynamic traffic prioritization and to offer a flexible foundation that can observe diverse network domains while maintaining efficient performance under constrained computational conditions.</abstract>
    <parentTitle language="eng">CSCS '25: Proceedings of the 2nd Cyber Security in CarS Workshop</parentTitle>
    <identifier type="doi">10.1145/3736130.3764510</identifier>
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    <enrichment key="CorrespondingAuthor">Julian Graf</enrichment>
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    <author>Julian Graf</author>
    <author>Murad Hachani</author>
    <author>Sebastian Fischer</author>
    <author>Rudolf Hackenberg</author>
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    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>11</pageNumber>
    <edition/>
    <issue/>
    <volume>167</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
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    <title language="eng">Influence of plant dimensioning and location on the ecology of PEM electrolysis</title>
    <abstract language="eng">PV and wind systems with PEM electrolysis offer great potential for producing hydrogen with low emissions. Our research has identified the ecologically optimal size of PEM in relation to fixed PV/wind capacities. We calculate efficiencies and production volumes for PEM with 240 capacity and site variations. We analyse the global warming potential of all systems and draw conclusions about the optimal system design. The lowest GWP is achieved at the site with the highest full load hours with 1.32 kg CO2-eq/kg H2 (Wind, 28 MW electrolysis) and 4.24 kg CO2-eq/kg H2 (PV, 23 MW electrolysis). We have identified a clear trend: increasing PV/wind full load hours leads to higher ideal PEM capacities. However, there is a significant discrepancy between the ideal economic and ecological capacity. Furthermore, higher electrolysis capacities can achieve lower emissions as they increasingly operate at a more efficient partial load.</abstract>
    <parentTitle language="eng">International Journal of Hydrogen Energy</parentTitle>
    <identifier type="issn">0360-3199</identifier>
    <identifier type="doi">10.1016/j.ijhydene.2025.151039</identifier>
    <enrichment key="CorrespondingAuthor">Michael Heberl</enrichment>
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    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Michael Heberl</author>
    <author>Andreas Hofrichter</author>
    <author>Daniel Rank</author>
    <author>Franz Bauer</author>
    <author>Michael Sterner</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Electrolysis</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Life cycle analysis</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Global warming potential</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Plant design</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Renewable energy</value>
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    <collection role="institutes" number="FakEI">Fakultät Elektro- und Informationstechnik</collection>
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    <collection role="oaweg" number="">Corresponding author der OTH Regensburg</collection>
    <collection role="persons" number="sternerfenes">Sterner, Michael (Prof. Dr.) - FENES / Forschungsgruppe Energiespeicher</collection>
    <collection role="funding" number="">DEAL Elsevier</collection>
    <collection role="DFGFachsystematik" number="1">Ingenieurwissenschaften</collection>
    <collection role="othforschungsschwerpunkt" number="">Nachhaltige Lebensräume</collection>
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    <publishedYear>2025</publishedYear>
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    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>11</pageNumber>
    <edition/>
    <issue>1</issue>
    <volume>3104</volume>
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    <title language="eng">Face-wise prediction of sheet-metal drawability using graph neural networks</title>
    <abstract language="eng">The early design phase of deep-drawn structural components involves time-consuming iterative development. Traditional drawability assessments rely on finite element simulations, which are computationally expensive and slow the design process. Alternative machine learning (ML) approaches show promise in accelerating this process but face challenges with existing methods. Existing low-dimensional ML models only provide global predictions without identifying specific geometric regions prone to failure. High-dimensional models provide local predictions but require significant amounts of training data. We propose a data-driven approach leveraging graph neural networks (GNNs) for face-wise drawability prediction of sheet metal components in their computer-aided design (CAD) representation. Our method aims to bridge the gap between the computational efficiency of ML and the spatial resolution of simulation by providing face-wise insight into potential failure regions. This study utilises a dataset of parametric U-channel geometries with variability in both geometry and topology. Ground-truth labels are generated using inverse analysis simulations. Geometric entities are represented through the use of UV parameterisations, whereby 3D surfaces are mapped into 2D space to facilitate geometric encoding. Concurrently, the topological relationships are captured using a face adjacency graph. To address data scarcity, we evaluate how different amounts of training data affect model performance and perform ablation studies to analyse the impact of different CAD representation features. Our results show that the proposed approach achieves high accuracy even with limited training data. In addition, the ablation studies provide insights into the most critical CAD features, guiding future research. These results highlight the potential of our GNN to predict face-wise drawability in the early design phase.</abstract>
    <parentTitle language="eng">Journal of Physics: Conference Series</parentTitle>
    <identifier type="issn">1742-6588</identifier>
    <identifier type="doi">10.1088/1742-6596/3104/1/012053</identifier>
    <note>Corresponding author der OTH Regensburg: Philipp Stocker</note>
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    <enrichment key="CorrespondingAuthor">Philipp Stocker</enrichment>
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    <author>Philipp Stocker</author>
    <author>Tobias Lehrer</author>
    <author>Fabian Duddeck</author>
    <author>Marcus Wagner</author>
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  <doc>
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    <publishedYear>2024</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>16</pageNumber>
    <edition/>
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    <type>article</type>
    <publisherName>Springer Nature</publisherName>
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    <completedDate>2024-11-12</completedDate>
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    <title language="deu">IT/OT-Konvergenz: Status-Quo und Umsetzungsempfehlungen</title>
    <abstract language="deu">Organisationen machen große Anstrengungen zur Verbesserung ihrer Ambidextrie, d. h. ihrer Fähigkeit sowohl Exploitationsziele (z. B. Effizienz, Vorhersagbarkeit) als auch Explorationsziele (z. B. Anpassbarkeit, Innovation) zu erreichen. Obwohl gemäß der Praxisliteratur Technologie in Software-Projekten dabei eine zentrale Rolle spielen kann, gibt es kaum Forschung dazu, wie technologische Faktoren Ambidexterie in Software-Projekten beeinflussen. In dieser Studie untersuchen wir die Rolle dreier technologischer Faktoren: kontinuierliche Integration, Standardisierung und Microservice-Architektur. Die Ergebnisse einer Mehrinformanten-Umfrage in 95 Projekten in der Schweiz und Dänemark zeigen, dass kontinuierliche Integration und Standardisierung mit höherer Ambidexterie einhergehen, während der Zusammenhang zwischen Microservice-Architektur und Ambidextrie nicht signifikant ist. Unser Artikel geht über die existierende Forschung hinaus, indem er zeigt, dass kontinuierliche Integration und Standardisierung nicht nur Exploitation, sondern auch Exploration fördern können. Wir diskutieren auch Gründe für den insignifikanten Zusammenhang zwischen Microservice-Architektur und Ambidextrie.</abstract>
    <abstract language="eng">This study examines IT/OT Convergence in 31 predominantly large German companies. It presents an “IT/OT Governance Framework” as a specific model for successful convergence implementation. The analysis reveals a heterogeneous level of convergence maturity across the examined companies, the majority of which are at the beginning or in the implementation phase. Close cooperation between IT and OT is favored, but without IT completely taking over OT. An IT/OT tandem consisting of a CIO and a central OT responsible person is seen as the ideal way to take responsibility. Six specific recommendations were derived from the interviews and included in the IT/OT Governance Framework developed. These include ensuring top management support, using security as a driver, introducing a central OT responsible person, bringing IT and OT teams physically closer together, continuously demonstrating the added value of convergence, and taking a step-by-step approach to implementation.</abstract>
    <parentTitle language="deu">HMD Praxis der Wirtschaftsinformatik</parentTitle>
    <identifier type="doi">10.1365/s40702-024-01111-1</identifier>
    <identifier type="urn">urn:nbn:de:bvb:898-opus4-77937</identifier>
    <note>Corresponding author der OTH Regensburg: Markus Westner</note>
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    <enrichment key="CorrespondingAuthor">Markus Westner</enrichment>
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    <author>Carolin Hantsch</author>
    <author>Markus Westner</author>
    <author>Markus Matschi</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>IT/OT Convergence</value>
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    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Operational Technology</value>
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    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>OT</value>
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    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Governance</value>
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    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
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    <collection role="funding" number="">DEAL Springer Nature</collection>
    <collection role="institutes" number="">Labor Regensburg Strategic IT Management (ReSITM)</collection>
    <thesisPublisher>Ostbayerische Technische Hochschule Regensburg</thesisPublisher>
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    <pageLast/>
    <pageNumber>24</pageNumber>
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    <volume>10</volume>
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    <publisherName>MDPI</publisherName>
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    <completedDate>2025-12-04</completedDate>
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    <title language="eng">Is it worth it? Potential for reducing the environmental impact of bitumen roofing membrane production</title>
    <abstract language="eng">Between 51% and 72% of a bituminous roofing membrane used for structural water-proofing consists of organic material, predominantly bitumen - a derivative of crude oil refining - highlighting the strong dependence of this product on fossil resources. Considering that several tonnes of these membranes must be replaced every 30 to 50 years, substantial potential exists for emission reduction through the establishment of circular material systems. This study investigates this potential by analysing 26 Environmental Product Declarations (EPDs) and life cycle datasets from across Europe  covering the period from 2007 to 2023. To ensure comparability, all data were normalised to a declared unit of 1 kg of roofing membrane. The reinforcement layers were categorised into glass and polyester &amp; glass composites, and their differences were examined using Welch’s t-tests.&#13;
Correlative analyses and linear as well as multiple regression models were then applied to explore relationships between environmental indicators and the shares of organic and mineral mass fractions. The findings reveal that renewable energy sources, although currently representing only a small share of total production energy, provide a major lever for&#13;
reducing nearly all environmental impact categories. The type of reinforcement layer was also found to influence the demand for fossil resources, both materially and energetically.&#13;
For most environmental indicators, only multiple regression models can explain at least 30% of the variance based on the proportions of organic and mineral inputs. Overall, the study underscores the crucial importance of high-quality, transparently documented product data for accurately assessing the sustainability of building products. It further demonstrates that substituting fossil energy carriers with renewable sources and optimising material efficiency can substantially reduce environmental burdens, provided that methodological consistency and clarity of indicator definitions are maintained.</abstract>
    <parentTitle language="eng">Recycling</parentTitle>
    <identifier type="doi">10.3390/recycling10060208</identifier>
    <identifier type="urn">urn:nbn:de:bvb:898-opus4-86873</identifier>
    <note>Corresponding author der OTH Regensburg: Michael Schmid</note>
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    <author>Michael T. Schmid</author>
    <author>Charlotte Thiel</author>
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      <language>eng</language>
      <type>uncontrolled</type>
      <value>bitumen sealing</value>
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    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>bitumen recycling</value>
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    <subject>
      <language>eng</language>
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      <value>circular construction</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>correlation analysis</value>
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    <subject>
      <language>eng</language>
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      <value>LCA</value>
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    <thesisPublisher>Ostbayerische Technische Hochschule Regensburg</thesisPublisher>
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