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  <doc>
    <id>1444</id>
    <completedYear/>
    <publishedYear>2017</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>VDE-Verlag</publisherName>
    <publisherPlace>Berlin</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2017-10-25</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Miniaturisierter plasmonischer Sensor für das Monitoring von Weichmachern in Gewässerproben</title>
    <parentTitle language="deu">7. MikroSystemTechnik Kongress "MEMS, Mikroelektronik, Systeme", 23.-25. Oktober 2017, München</parentTitle>
    <identifier type="isbn">978-3-8007-4491-6</identifier>
    <enrichment key="opus.source">publish</enrichment>
    <author>Johannes Fischer</author>
    <collection role="ddc" number="621">Angewandte Physik</collection>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1440</id>
    <completedYear/>
    <publishedYear>2018</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferencesummary</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2018-05-28</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Motionless SPR-angle scan with a miniaturized device</title>
    <parentTitle language="eng">Europtrode XIV, Naples, 25-28 March 2018</parentTitle>
    <enrichment key="opus.source">publish</enrichment>
    <author>Peter Hausler</author>
    <author>Carina Roth</author>
    <author>Thomas Vitzthumecker</author>
    <author>Johannes Fischer</author>
    <author>Rudolf Bierl</author>
    <collection role="ddc" number="621">Angewandte Physik</collection>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1439</id>
    <completedYear/>
    <publishedYear>2018</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2018-01-27</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Portable Measurement Unit for NO2 Trace Gas Detection</title>
    <parentTitle language="eng">PHOTOPTICS 2018, 6th International Conference on Photonics, Optics and Laser Technology, 25 - 27 January 2018, Funchal Madeira</parentTitle>
    <enrichment key="opus.source">publish</enrichment>
    <author>Stefan Weigl</author>
    <author>Peter Gaida</author>
    <author>Thomas Rück</author>
    <author>Rudolf Bierl</author>
    <collection role="ddc" number="621">Angewandte Physik</collection>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1453</id>
    <completedYear/>
    <publishedYear>2015</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>report</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2015-01-01</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Herstellung und Analyse der Resonanzfrequenz eines MEMS Cantilever für das CEPAS Verfahren</title>
    <abstract language="deu">Diese Abhandlung beschreibt das Konzept eines mikroeletromechanischen Systems (MEMS), das im Messverfahren der cantilever enhanced  photoacoustic spectroscopy (CEPAS) Verwendung finden soll. &#13;
Es wird die Herstellung eines einseitig eingespannten Biegebalkens aus Silizium mittels deep reactiv ion etching (DRIE) beschrieben. Des Weiteren wird die Resonanzfrequenz dieses Cantilevers mit Hilfe Laservibrometertechnik untersucht. Die resultierenden resonanten Schwingungen 0.Ordnung werden mit den Ergebnissen einer vereinfachten theoretischen Näherung verglichen. Die Messergebnisse stehen in gutem Zusammenhang mit den theoretischen Werten. Solche Cantilever, die aus silicon on insula tor (SOI) Wafer angefertigt wurden, weisen bei einer Zielfrequenz ein mittlere Abweichung von Δf = 118±26Hz (bzw.Δf =0,76±0,17%) auf.</abstract>
    <enrichment key="opus.source">publish</enrichment>
    <author>J. Unger</author>
    <author>Thomas Rück</author>
    <author>Ferdinand Landgraf</author>
    <author>Rudolf Bierl</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1449</id>
    <completedYear/>
    <publishedYear>2016</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst>192</pageFirst>
    <pageLast>198</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>Fachhochschule Landshut</publisherName>
    <publisherPlace>Landshut</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2016-03-09</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Gestapelte Au-Al-Au und Au-Ag-Au Schichten als aktive Schichten für die Oberflächenplasmonenresonanzspektroskopie</title>
    <parentTitle language="deu">5. Landshuter Symposium Mikrosystemtechnik, März 2016</parentTitle>
    <identifier type="isbn">978-3-9812696-9-7</identifier>
    <enrichment key="opus.source">publish</enrichment>
    <author>Sven Holler</author>
    <author>Peter Hausler</author>
    <author>Carina Roth</author>
    <author>Rudolf Bierl</author>
    <collection role="ddc" number="621">Angewandte Physik</collection>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1450</id>
    <completedYear/>
    <publishedYear>2016</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst>200</pageFirst>
    <pageLast>205</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>Fachhochschule Landshut</publisherName>
    <publisherPlace>Landshut</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2016-03-09</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Einbindung eines CMOS-Detektors in einen hochintegrierten SPR-Sensor</title>
    <parentTitle language="deu">5. Landshuter Symposium Mikrosystemtechnik, März 2016</parentTitle>
    <identifier type="isbn">78-3-9812696-9-7</identifier>
    <enrichment key="opus.source">publish</enrichment>
    <author>Carina Roth</author>
    <author>Peter Hausler</author>
    <author>Rudolf Bierl</author>
    <collection role="ddc" number="621">Angewandte Physik</collection>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1562</id>
    <completedYear/>
    <publishedYear>2014</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>65</pageFirst>
    <pageLast>80</pageLast>
    <pageNumber/>
    <edition/>
    <issue>2</issue>
    <volume>63</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2021-03-21</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Experimental investigation of damping properties of unidirectionally and fabric reinforced plastics by the free decay method</title>
    <abstract language="eng">Purpose: &#13;
of this paper is experimental investigation of damping properties of unidirectionally and fabric reinforced plastics by the free decay method. &#13;
Design/methodology/approach: &#13;
For the evaluation of the presumed effect experimental structural dynamic investigations comparing unidirectionally and fabric reinforced plastics are carried out. In detail the free decay behaviour of flat beamlike specimens under fixed-free boundary conditions and relatively constant and reproducible displacement excitation is investigated. Findings: The vibrating structure has been measured by a laser scanning vibrometer PSV 400 from POLYTEC. In both cases evaluation of the results yields enhanced damping properties of the specimens with fabric reinforcement compared to the unidirectionally reinforced specimens. The results justify the presumed acting of a mesomechanic kinematic. &#13;
Research limitations/implications:&#13;
 The results show that in either case the material damping in terms of the logarithmic decrement of the fabric reinforced material is higher than the material damping in of the unidirectionally reinforced material. Additionally, when the fabric reinforced specimens are addressed, in each case the plain weave reinforced specimens exhibited higher values of the material damping as the twill weave 2/2 reinforced ones. &#13;
Originality/value: &#13;
Ondulations in fabrics as a textile semi-finished product are caused by the alternating crossing of warp and fill yarns. In the mesoscopic scale the acting of a mesomechanic kinematic is presumed to enhance the damping properties under cyclic elastic deformation. For the evaluation of the presumed effect experimental structural dynamic investigations comparing unidirectionally and fabric reinforced plastics are carried out.</abstract>
    <parentTitle language="eng">Journal of Achievements in Materials and Manufacturing Engineering</parentTitle>
    <enrichment key="opus.source">publish</enrichment>
    <author>Marco Romano</author>
    <author>Matthias Micklitz</author>
    <author>Florian Olbrich</author>
    <author>Rudolf Bierl</author>
    <author>Ingo Ehrlich</author>
    <author>Norbert Gebbeken</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>structural vibration</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>damping</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>fibre reinforced plastics</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>mesomechanic scale</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>fabric reinforced layer</value>
    </subject>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="institutes" number="FAKMB">Fakultät Maschinenbau</collection>
    <collection role="persons" number="ehrlichlft">Ehrlich, Ingo (Prof. Dr.) - Labor Faserverbundtechnik</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16316">Produktion und Systeme</collection>
    <collection role="institutes" number="">Labor Faserverbundtechnik (LFT)</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1563</id>
    <completedYear/>
    <publishedYear>2014</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2021-03-21</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">A Comparison of Correlation and Zero-Crossing Based Techniques in Ultrasonic Measurement</title>
    <abstract language="eng">Ultrasound measurement technology has advancedin previous decades due to positive developments in computing power and lower cost for the  necessary  hardware. Correlation-based processing can be advantageous  for high-accuracy measurements, especially in noisy environments.   Higher computational load makes correlation less attractive for   industrialapplications, though, favouring traditional processing techniques. A platform for comparing various processing techniques  hasbeen developed. It was found that both zero-crossing detectionas well as correlation can achieve very high accuracy over a hightemperature range but that correlation-based processing can lead to a significant  precision bias depending on system bandwidth.</abstract>
    <parentTitle language="eng">10th International Symposium on Applied Reconfigurable Computing (ARC'2014), Vilamoura, Algarve, Portugal, 14 - 16 April, 2014</parentTitle>
    <enrichment key="opus.source">publish</enrichment>
    <author>Simon Jobst</author>
    <author>Rudolf Bierl</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1569</id>
    <completedYear/>
    <publishedYear>2012</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2021-03-21</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Implementation of a dual-phase lock-in amplifier on a TMS320C5515 digital signal processor</title>
    <abstract language="deu">A digital dual-phase lock-in amplifier that is capable to run on a low-cost, low-power platform comprising a 16-bit fixed-point digital signal processor was developed. This is achieved by a set of optimised digital filters including an exponential averager to adjust the time constant of the overall filter. The reference frequency is generated using a direct digital synthesis source utilising angle decomposition with a resolution of 1 Hz. The digital lock-in algorithm is described and the performance of the algorithm is analysed. The experimental results show that the developed lock-in amplifier achieves similar performance to a commercially available lock-in amplifier.</abstract>
    <parentTitle language="eng">Proceedings of the 5th European DSP Education and Research Conference (EDERC), 13-14 Sept. 2012, Amsterdam</parentTitle>
    <identifier type="doi">10.1109/EDERC.2012.6532217</identifier>
    <enrichment key="opus.source">publish</enrichment>
    <author>Matthias Hofmann</author>
    <author>Rudolf Bierl</author>
    <author>Thomas Rück</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16316">Produktion und Systeme</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1559</id>
    <completedYear/>
    <publishedYear>2015</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2021-03-21</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Specification of an improved photoacoustic setup for high-sensitive, low-cost NO2 trace gas detection</title>
    <parentTitle language="eng">18th International Conference on Photoacoustic and Photothermal Phenomena (ICPPP18), 2015, September 6-10, Novi Sad, Serbia</parentTitle>
    <enrichment key="opus.source">publish</enrichment>
    <author>Thomas Rück</author>
    <author>Ferdinand Landgraf</author>
    <author>I. Läpple</author>
    <author>J. Unger</author>
    <author>Frank-Michael Matysik</author>
    <author>Rudolf Bierl</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1565</id>
    <completedYear/>
    <publishedYear>2014</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2021-03-21</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">A Conductivity Probe for the Determination of Carbon Dioxide Tension at the Oxygenator Exhaust Outlet during Extracorporeal Membrane Oxygenation (ECMO)</title>
    <parentTitle language="eng">analytica Conference 2014, 1. bis 4. April, München</parentTitle>
    <enrichment key="opus.source">publish</enrichment>
    <author>Bastiaan van der Weerd</author>
    <author>Rudolf Bierl</author>
    <author>Frank-Michael Matysik</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1566</id>
    <completedYear/>
    <publishedYear>2014</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2021-03-21</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">A Conductivity Probe for the Determination of Carbon Dioxide Tension at the Oxygenator Exhaust Outlet during Extracorporeal Membrane Oxygenation (ECMO)</title>
    <parentTitle language="eng">Electrochemistry 2014, September 22 - 24, Mainz</parentTitle>
    <enrichment key="opus.source">publish</enrichment>
    <author>Bastiaan van der Weerd</author>
    <author>Rudolf Bierl</author>
    <author>Frank-Michael Matysik</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1564</id>
    <completedYear/>
    <publishedYear>2014</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2021-03-21</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">A Planar Conductivity Probe for CO2 Determination at the Oxygenator Outlet</title>
    <parentTitle language="deu">Doktorandenseminar GDCh Prozessanalytik 2014, Berlin</parentTitle>
    <enrichment key="opus.source">publish</enrichment>
    <author>Bastiaan van der Weerd</author>
    <author>Rudolf Bierl</author>
    <author>Frank-Michael Matysik</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>2628</id>
    <completedYear/>
    <publishedYear>2021</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1</pageFirst>
    <pageLast>9</pageLast>
    <pageNumber/>
    <edition/>
    <issue>7</issue>
    <volume>9</volume>
    <type>article</type>
    <publisherName>MDPI</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Nanoparticle Determination in Water by LED-Excited Surface Plasmon Resonance Imaging</title>
    <abstract language="eng">The increasing popularity of nanoparticles in many applications has led to the fact that these persistent materials pollute our environment and threaten our health. An online sensor system for monitoring the presence of nanoparticles in fresh water would be highly desired. We propose a label-free sensor based on SPR imaging. The sensitivity was enhanced by a factor of about 100 by improving the detector by using a high-resolution camera. This revealed that the light source also needed to be improved by using LED excitation instead of a laser light source. As a receptor, different self-assembled monolayers have been screened. It can be seen that the nanoparticle receptor interaction is of a complex nature. The best system when taking sensitivity as well as reversibility into account is given by a dodecanethiol monolayer on the gold sensor surface. Lanthanide-doped nanoparticles, 29 nm in diameter and with a similar refractive index to the most common silica nanoparticles were detected in water down to 1.5 mu g mL(-1). The sensor can be fully regenerated within one hour without the need for any washing buffer. This sensing concept is expected to be easily adapted for the detection of nanoparticles of different size, shape, and composition, and upon miniaturization, suitable for long-term applications to monitor the quality of water.</abstract>
    <parentTitle language="eng">Chemosensors</parentTitle>
    <identifier type="doi">10.3390/chemosensors9070175</identifier>
    <identifier type="issn">2227-9040</identifier>
    <enrichment key="opus.import.date">2022-01-27T15:41:12+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Lukas Wunderlich</author>
    <author>Peter Hausler</author>
    <author>Susanne Maerkl</author>
    <author>Rudolf Bierl</author>
    <author>Thomas Hirsch</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>ENGINEERED NANOPARTICLES</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>imaging</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>nanoparticle</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>plasmon resonance</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>REFRACTIVE-INDEX</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>sensor</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>surface</value>
    </subject>
    <collection role="ddc" number="621">Angewandte Physik</collection>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="oaweg" number="">Gold Open Access- Erstveröffentlichung in einem/als Open-Access-Medium</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>2755</id>
    <completedYear/>
    <publishedYear>2019</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>169</pageFirst>
    <pageLast>195</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>Springer Nature</publisherName>
    <publisherPlace>Cham</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Miniaturized Surface Plasmon Resonance Based Sensor Systems</title>
    <abstract language="eng">Surface Plasmon Resonance (SPR) is a well-known and established technology in bioanalysis and pharmaceutical sciences. Due to the expensive instrumentation and the need of trained people, it is mainly limited to applications in laboratories. However, there are some areas like environmental monitoring, chemical processing and civil infrastructure, which urgently need new sensor technologies. SPR has the potential to serve these fields. In order to be qualified for a use in these areas SPR has to overcome some hurdles. The instrumentation has to be robust, small in size and cheap. A device, which fits these needs, will be a micro-opto-electro-mechanical system (MOEMS) with integrated intelligent algorithms. In this book chapter, examples of miniaturized SPR devices are introduced, the limitations which have to be overcome as well as the possibilities for future applications are proposed. Due to the manifold advantages of this technology and the dropping prices for imaging sensors, Surface Plasmon Resonance imaging (SPRi) might become one of the leading technologies for SPR smart sensor systems.</abstract>
    <parentTitle language="eng">Optics, Photonics and Laser Technology 2018</parentTitle>
    <subTitle language="deu">Opportunities and Challenges</subTitle>
    <identifier type="isbn">978-3-030-30112-5</identifier>
    <identifier type="doi">10.1007/978-3-030-30113-2_8</identifier>
    <enrichment key="opus.import.date">2022-02-09T06:20:59+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="OtherSeries">Springer Series in Optical Sciences ; 223</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Peter Hausler</author>
    <author>Carina Roth</author>
    <author>Thomas Vitzthumecker</author>
    <author>Rudolf Bierl</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>5442</id>
    <completedYear/>
    <publishedYear>2022</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>Optica Publishing Group</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Creating a Digital Twin of a Photoacoustic Gas Sensor for Methane Detection in Complex Gas Matrices</title>
    <abstract language="deu">We present the calculation results from a digital twin (DT) of our photoacoustic (PA) sensor for methane detection, regarding gas composition, temperature and pressure variations.</abstract>
    <parentTitle language="eng">Proceedings Optical Sensors and Sensing Congress 2022 (AIS, LACSEA, Sensors, ES): 11–15 July 2022, Vancouver, British Columbia, Canada</parentTitle>
    <identifier type="doi">10.1364/LACSEA.2022.LW4D.2</identifier>
    <identifier type="isbn">978-1-957171-10-4</identifier>
    <enrichment key="OtherSeries">Technical Digest Series (Optica Publishing Group, 2022), paper LW4D.2.</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Max Müller</author>
    <author>Thomas Rück</author>
    <author>Simon Jobst</author>
    <author>Jonas Pangerl</author>
    <author>Rudolf Bierl</author>
    <author>Frank-Michael Matysik</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>6555</id>
    <completedYear/>
    <publishedYear>2023</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>33</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Multivariate analysis and digital twin modelling: Alternative approaches to evaluate molecular relaxation in photoacoustic spectroscopy</title>
    <abstract language="eng">A comparative analysis of two different approaches developed to deal with molecular relaxation in photoacoustic spectroscopy is here reported. The first method employs a statistical analysis based on partial least squares regression, while the second method relies on the development of a digital twin of the photoacoustic sensor based on the theoretical modelling of the occurring relaxations. Methane detection within a gas matrix of synthetic air with variable humidity level is selected as case study. An interband cascade laser emitting at 3.345 µm is used to target methane absorption features. Two methane concentration ranges are explored targeting different absorptions, one in the order of part-per-million and one in the order of percent, while water vapor absolute concentration was varied from 0.3 % up to 2 %. The results achieved employing the detection techniques demonstrated the possibility to efficiently retrieve the target gas concentrations with accuracy &gt; 95 % even in the case of strong influence of relaxation effects.</abstract>
    <parentTitle language="eng">Photoacoustics</parentTitle>
    <identifier type="doi">10.1016/j.pacs.2023.100564</identifier>
    <identifier type="issn">2213-5979</identifier>
    <enrichment key="opus.import.date">2023-10-16T20:23:06+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Andrea Zifarelli</author>
    <author>Aldo Francesco Pio Cantatore</author>
    <author>Angelo Sampaolo</author>
    <author>Max Mueller</author>
    <author>Thomas Rueck</author>
    <author>Christine Hoelzl</author>
    <author>Hubert Rossmadl</author>
    <author>Pietro Patimisco</author>
    <author>Vincenzo Spagnolo</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>digital twin model</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>methane detection over a wide concentration range</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>multivariate analysis</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Partial Least Squares Regression</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>QEPAS sensor</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>relaxation effects photoacoustic spectroscopy</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>water vapor influence on relaxation</value>
    </subject>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="oaweg" number="">Hybrid Open Access - OA-Veröffentlichung in einer Subskriptionszeitschrift/-medium</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>6538</id>
    <completedYear/>
    <publishedYear>2023</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>Optica Publishing Group</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Using a Modulated Quantum Cascade Laser for Photoacoustic Spectra Recording of Exhaled Acetone and Main Breath Components</title>
    <abstract language="eng">Photoacoustic spectra of main breath components together with acetone are presented demonstrating spectral linearity towards different concentrations and compositions. The acetone 3σ detection limit at 1209 cm−1 is 0.28 ppbV</abstract>
    <parentTitle language="deu">Optical Sensors and Sensing Congress 2022 (AIS, LACSEA, Sensors, ES)</parentTitle>
    <identifier type="doi">10.1364/AIS.2022.ATu3G.1</identifier>
    <enrichment key="OtherSeries">Technical Digest Series (Optica Publishing Group, 2022), paper ATu3G.1.</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Jonas Pangerl</author>
    <author>Elisabeth Wittmann</author>
    <author>Stefan Weigl</author>
    <author>Max Müller</author>
    <author>Rudolf Bierl</author>
    <author>Frank-Michael Matysik</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>5404</id>
    <completedYear/>
    <publishedYear>2022</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>Optica Publishing Group</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Design and Characterization of a Low-Cost Photoacoustic Sensor for NO2 Using Lateral Illumination and Background Suppression</title>
    <abstract language="eng">We introduce a low-cost photoacoustic NO2 sensor based on lateral LED illumination and optical background signal compensation. The 3σ limit of detection (LOD) was identified to be 24 ppbV.</abstract>
    <parentTitle language="eng">Imaging and Applied Optics Congress 2022 (3D, AOA, COSI, ISA, pcAOP): 11–15 July 2022, Vancouver, British Columbia, Canada</parentTitle>
    <identifier type="doi">10.1364/3D.2022.JTu2A.10</identifier>
    <identifier type="isbn">978-1-957171-09-8</identifier>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Lukas Escher</author>
    <author>Thomas Rück</author>
    <author>Simon Jobst</author>
    <author>Martin König</author>
    <author>Rudolf Bierl</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>7330</id>
    <completedYear/>
    <publishedYear>2024</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>preprint</type>
    <publisherName>Elsevier / SSRN</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Photoacoustic Trace-Analysis of Breath Isoprene and Acetone Via Interband- and Quantum Cascade Lasers</title>
    <abstract language="eng">This research presents two laser-based photoacoustic approaches for analyzing exhaled breath isoprene and acetone. The integration of a PTR-ToF-MS as a reference device ensured the reliability and accuracy of the PAS systems that is based on an ICL for isoprene and a QCL for acetone detection. The calibration yielded limits of detection of 26.9 ppbV and 1.7 ppbV, respectively, and corresponding normalized noise equivalent absorption coefficients (NNEAs) of 5.0E-9 Wcm-1Hz-0.5 and 4.9E-9 Wcm-1Hz-0.5. Laboratory as well as real breath sample measurements from alveolar breath revealed a robust system performance, with only one outlier within the static isoprene measurements. However, discrepancies emerged under dynamic breath sampling conditions, emphasizing the need for further optimization. Especially by knowing the dynamic nature and endogenous origin of exhaled isoprene our findings highlight the potential of breath analysis for non-invasive physio-metabolic and pathophysiological monitoring towards point-of-care devices.</abstract>
    <identifier type="doi">10.2139/ssrn.4834735</identifier>
    <enrichment key="opus.doi.autoCreate">false</enrichment>
    <enrichment key="opus.urn.autoCreate">true</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Jonas Pangerl</author>
    <author>Pritam Sukul</author>
    <author>Thomas Rück</author>
    <author>Lukas Escher</author>
    <author>Wolfram Miekisch</author>
    <author>Rudolf Bierl</author>
    <author>Frank-Michael Matysik</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>photoacoustic spectroscopy</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>breath analysis/profiling</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>real-time mass spectroscopy</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>isoprene</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>acetone</value>
    </subject>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>7702</id>
    <completedYear/>
    <publishedYear>2025</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>12</pageNumber>
    <edition/>
    <issue/>
    <volume>424</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Photoacoustic trace-analysis of breath isoprene and acetone via interband- and Quantum Cascade Lasers</title>
    <abstract language="eng">This research presents two laser-based photoacoustic approaches for analyzing exhaled breath isoprene and acetone. The integration of a PTR-ToF-MS as a reference device ensured the reliability and accuracy of the photoacoustic systems that is based on an ICL for isoprene and a QCL for acetone detection. The calibration yielded limits of detection of 26.9 ppbV and 1.7 ppbV, respectively, and corresponding normalized noise equivalent absorption coefficients (NNEAs) of 5.0E-9 Wcm 1Hz 0.5 and 4.9E-9 Wcm 1Hz 0.5. Laboratory as well as real breath sample measurements from alveolar breath revealed a robust system performance, with only one outlier within the static isoprene measurements. However, discrepancies emerged under dynamic breath sampling conditions, emphasizing the need for further optimization. Especially by knowing the dynamic nature and endogenous origin of exhaled isoprene our findings highlight the potential of breath analysis for non-invasive&#13;
physio-metabolic and pathophysiological monitoring towards point-of-care devices</abstract>
    <parentTitle language="eng">Sensors and Actuators: B. Chemical</parentTitle>
    <identifier type="doi">10.1016/j.snb.2024.136886</identifier>
    <identifier type="urn">urn:nbn:de:bvb:898-opus4-77024</identifier>
    <note>Corresponding author der OTH Regensburg: Jonas Pangerl</note>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <enrichment key="CorrespondingAuthor">Jonas Pangerl</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Jonas Pangerl</author>
    <author>Pritam Sukul</author>
    <author>Thomas Rück</author>
    <author>Lukas Escher</author>
    <author>Wolfram Miekisch</author>
    <author>Rudolf Bierl</author>
    <author>Frank-Michael Matysik</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Photoacoustic spectroscopy</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Breath analysis/profiling</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Real-time mass spectrometry</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Isoprene</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Acetone</value>
    </subject>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="oaweg" number="">Hybrid Open Access - OA-Veröffentlichung in einer Subskriptionszeitschrift/-medium</collection>
    <collection role="oaweg" number="">Corresponding author der OTH Regensburg</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
    <collection role="funding" number="">DEAL Elsevier</collection>
    <collection role="DFGFachsystematik" number="1">Ingenieurwissenschaften</collection>
    <thesisPublisher>Ostbayerische Technische Hochschule Regensburg</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-oth-regensburg/files/7702/Pangerl_Sensors_Actuators_2025.pdf</file>
  </doc>
  <doc>
    <id>5752</id>
    <completedYear/>
    <publishedYear>2022</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>AMA (Association for Sensors + Measurement)</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation>DECHEMA, Gesellschaft für Chemische Technik und Biotechnologie</contributingCorporation>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Digitaler Zwilling photoakustischer Spurengassensoren zur Prozessüberwachung</title>
    <abstract language="deu">Stickstoffdioxid (NO2) wird hauptsächlich durch anthropogene Verbrennungsprozesse in Verkehr und Industrie in die Umgebungsluft eingebracht [1]. Die stark reaktive, oxidative Wirkung von NO2 kann bei Exposition mit höheren Konzentrationen Reizungen und allergische Reaktionen in den Atemwegen hervorrufen. Weiter führt NO2 zur Bildung von saurem Regen, Smog und Ozon (O3) die sich ebenso negativ auf die menschliche Gesundheit und Umwelt auswirken [2,3]. Aufgrund dieser Effekte wird die Spurengaskonzentration von NO2 in der Luft in Deutschland an ausgewählten, verkehrsreichen Orten gemessen.</abstract>
    <parentTitle language="deu">16. Dresdner Sensor-Symposium 2022: Vorträge</parentTitle>
    <identifier type="doi">10.5162/16dss2022/3.3</identifier>
    <identifier type="isbn">978-3-9819376-7-1</identifier>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Lukas Escher</author>
    <author>Max Müller</author>
    <author>Thomas Rück</author>
    <author>Simon Jobst</author>
    <author>Rudolf Bierl</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>7737</id>
    <completedYear/>
    <publishedYear>2024</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>40</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Kinetic cooling in mid-infrared methane photoacoustic spectroscopy: A quantitative analysis via digital twin verification</title>
    <abstract language="eng">This study presents a detailed quantitative analysis of kinetic cooling in methane photoacoustic spectroscopy, leveraging the capabilities of a digital twin model. Using a quantum cascade laser tuned to 1210.01 cm⁻¹, we investigated the effects of varying nitrogen-oxygen matrix compositions on the photoacoustic signals of 15 ppmV methane. Notably, the photoacoustic signal amplitude decreased with increasing oxygen concentration, even falling below the background signal at oxygen levels higher than approximately 6 %V. This phenomenon was attributed to kinetic cooling, where thermal energy is extracted from the surrounding gas molecules rather than added, as validated by complex vector analysis using a previously published digital twin model. The model accurately reproduced complex signal patterns through simulations, providing insights into the underlying molecular mechanisms by quantifying individual collision contributions. These findings underscore the importance of digital twins in understanding the fundamentals of photoacoustic signal generation at the molecular level.</abstract>
    <parentTitle language="eng">Photoacoustics</parentTitle>
    <identifier type="doi">10.1016/j.pacs.2024.100652</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Creative Commons - CC BY-NC - Namensnennung - Nicht kommerziell 4.0 International</licence>
    <author>Thomas Rück</author>
    <author>Jonas Pangerl</author>
    <author>Lukas Escher</author>
    <author>Simon Jobst</author>
    <author>Max Müller</author>
    <author>Rudolf Bierl</author>
    <author>Frank-Michael Matysik</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="oaweg" number="">Gold Open Access- Erstveröffentlichung in einem/als Open-Access-Medium</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>6464</id>
    <completedYear>2023</completedYear>
    <publishedYear>2023</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>3530</pageFirst>
    <pageLast>3537</pageLast>
    <pageNumber/>
    <edition/>
    <issue>9</issue>
    <volume>8</volume>
    <type>article</type>
    <publisherName>American Chemical Society</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Semi-Selective Array for the Classification of Purines with Surface Plasmon Resonance Imaging and Deep Learning Data Analysis</title>
    <abstract language="eng">In process analytics or environmental monitoring, the real-time recording of the composition of complex samples over a long period of time presents a great challenge. Promising solutions are label-free techniques such as surface plasmon resonance (SPR) spectroscopy. They are, however, often limited due to poor reversibility of analyte binding. In this work, we introduce how SPR imaging in combination with a semi-selective functional surface and smart data analysis can identify small and chemically similar molecules. Our sensor uses individual functional spots made from different ratios of graphene oxide and reduced graphene oxide, which generate a unique signal pattern depending on the analyte due to different binding affinities. These patterns allow four purine bases to be distinguished after classification using a convolutional neural network (CNN) at concentrations as low as 50 μM. The validation and test set classification accuracies were constant across multiple measurements on multiple sensors using a standard CNN, which promises to serve as a future method for developing online sensors in complex mixtures.</abstract>
    <parentTitle language="eng">ACS sensors</parentTitle>
    <identifier type="doi">10.1021/acssensors.3c01114</identifier>
    <enrichment key="opus.import.date">2023-08-21T08:29:45+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Simon Jobst</author>
    <author>Patrick Recum</author>
    <author>Ángela Écija-Arenas</author>
    <author>Elisabeth Moser</author>
    <author>Rudolf Bierl</author>
    <author>Thomas Hirsch</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>surface plasmon resonance imaging</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>functional surface</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>graphene oxide</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>reduced graphene oxide</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>2D materials</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>pattern recognition</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>small-molecule sensing</value>
    </subject>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>851</id>
    <completedYear/>
    <publishedYear>2019</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>11</pageNumber>
    <edition/>
    <issue/>
    <volume>Vol. 11028</volume>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2019-04-11</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Surface plasmon resonance imaging for detection of drug metabolites in water</title>
    <abstract language="eng">The analysis of surface water, groundwater, drinking water as well as sewage is important to get information about the contamination of the water cycle. Currently, these time-consuming investigations require special equipment, like for example hyphenated mass spectrometry. Surface plasmon resonance (SPR) is a faster alternative as it is highly sensitive to changes in the dielectric medium next to a thin metal layer and makes it a quasi-universal detector. Therefore, and due to the labelfree nature, SPR is a widely used sensing tool for real‐time monitoring of molecular interactions of various analytes. SPR imaging (SPRi) has several advantages to standard surface plasmon resonance, as it allows to observe many analytes in parallel as well as the integration of referencing technologies. However, the homogenous illumination of a large area (several millimeters) with a small light source is challenging and demands new approaches. Allopurinol, a drug used to lower the blood concentration of urate and hence decrease the affection of gout, gets metabolized to oxipurinol in the body and dropped out almost entirely by urinary excretion. After wastewater treatment, concentrations of oxipurinol up to 21.7 μg•L-1 are detected. Further tracking of oxipurinol in the urban water cycle showed its presence in rivers and streams or even in groundwater. Therefore, the high biological stability of oxipurinol allows this molecule to be used as a marker for domestic wastewater in the environment. For the detection of oxipurinol by SPR graphene was used as receptive layer, as the analyte can bind via π-stacking to this surface. An SPRi technique was developed and compared to conventional SPR system for the detection of oxipurinol.</abstract>
    <parentTitle language="eng">Proceedings of SPIE, Optical Sensors 2019, 1 - 4 April 2019, Prague, Czech Republic</parentTitle>
    <identifier type="doi">10.1117/12.2522324</identifier>
    <identifier type="issn">0277-786X</identifier>
    <enrichment key="opus.source">publish</enrichment>
    <author>Peter Hausler</author>
    <author>Lukas Wunderlich</author>
    <author>Johannes Fischer</author>
    <author>Christina Pfab</author>
    <author>Simon Heckscher</author>
    <author>Thomas Hirsch</author>
    <author>Rudolf Bierl</author>
    <collection role="ddc" number="621">Angewandte Physik</collection>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1434</id>
    <completedYear/>
    <publishedYear>2017</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2017-06-08</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Miniaturisiertes Sensorsystem zur Oberflächenplasmonenresonanzspektroskopie</title>
    <abstract language="deu">Die Oberflächenplasmonenresonanzspektroskopie (SPR) wird aufgrund ihrer Vorzüge der zerstörungs- und markierungsfreien Messung, sowie der hohen Sensitivität sehr erfolgreich im Labormaßstab eingesetzt. Aufgrund der hohen Kosten geschieht dies bislang hauptsächlich in der Bioanalytik und dem Wirkstoffscreening. Gezeigt wird ein Ansatz, mit dem diese Technologie auf ein ultrakompaktes, kostengünstiges Sensorsystem übertragen wird, welches in der Lage ist, hoch-sensitiv Änderungen im Brechungsindex von 10-6 Einheiten (RIU) zu detektieren. Für Wasser bewirkt eine Temperaturschwankung von 1 K bereits eine Änderung von 1 mRIU. Daher wird durch ein integriertes Referenzsystem, sowie die Miniaturisierung erreicht, dass das System gegenüber Temperaturschwankungen, weitestgehend stabil ist. In dem MOEMS wird anstatt der konventionellen 1-Punkt bzw. 2-Punkt Messung ein bildgebendes Verfahren angewendet. Die Sensorfläche von 15 x 15 mm wird dabei mit einem handelsüblichen 4 Mio. Pixel CMOS Sensor ausgewertet. Um verlässliche Datenpunkte zu erhalten benötigt man eine Fläche von 10 x 10 Pixel. Demzufolge können auf dem Sensor theoretisch bis zu 40.000 Sensorspots parallel ausgewertet werden.</abstract>
    <parentTitle language="deu">118. Jahrestagung der deutschen Gesellschaft für angewandte Optik (DGaO), 6.-10. Juni 2017, Dresden</parentTitle>
    <enrichment key="opus.source">publish</enrichment>
    <author>Peter Hausler</author>
    <author>Carina Roth</author>
    <author>F. Aumer</author>
    <author>Thomas Vitzthumecker</author>
    <author>Christa Genslein</author>
    <author>Thomas Hirsch</author>
    <author>Rudolf Bierl</author>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Messtechnik</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Optische Systeme</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Spektroskopie</value>
    </subject>
    <collection role="ddc" number="621">Angewandte Physik</collection>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>877</id>
    <completedYear/>
    <publishedYear>2018</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>63</pageFirst>
    <pageLast>66</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>SciTePress</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2018-01-27</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Miniaturized Surface Plasmon Resonance based Sensor System</title>
    <abstract language="eng">We describe the miniaturization of the Surface Plasmon Resonance (SPR) technology which mainly finds its applications in pharmaceutical screening and biotechnology so far. SPR spectroscopy is a label-free, non-destructive and highly sensitive measurement principle detecting changes in the refractive index in striking distance to a gold surface. A transfer of this technology to a miniaturized sensor will broaden the range of possible applications. A promising feature which is included in the miniaturized system is the angle-dependent recording of the SPR signals without moving parts. Commercial SPR assays are mainly working with a small number of sensing spots. In contrast, the SPR imaging system shown here will allow to use an array of many sensing spots. In combination with chemical receptors designed as an artificial nose, the simultaneous detection of many analytes is envisioned for future applications.</abstract>
    <parentTitle language="eng">Proceedings of the 6th International Conference on Photonics, Optics and Laser Technology - PHOTOPTICS, Funchal, Madeira, Portugal</parentTitle>
    <identifier type="doi">10.5220/0006555400630066</identifier>
    <identifier type="isbn">978-989-758-286-8</identifier>
    <enrichment key="opus.source">publish</enrichment>
    <licence>Creative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International</licence>
    <author>Peter Hausler</author>
    <author>Christa Genslein</author>
    <author>Carina Roth</author>
    <author>Thomas Vitzthumecker</author>
    <author>Thomas Hirsch</author>
    <author>Rudolf Bierl</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Surface Plasmon Resonance Spectroscopy</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Sensor</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>SPR-imaging</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Miniaturization</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Micro-Opto-Electro-Mechanical Systems</value>
    </subject>
    <collection role="ddc" number="621">Angewandte Physik</collection>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1445</id>
    <completedYear/>
    <publishedYear>2017</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst>645</pageFirst>
    <pageLast>647</pageLast>
    <pageNumber/>
    <edition/>
    <issue>CD-ROM</issue>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>VDE-Verlag</publisherName>
    <publisherPlace>Berlin</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2021-03-04</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Mikro-Opto-Elektro-Mechanisches Sensorsystem zur Oberflächenplasmonenresonanzspektroskopie</title>
    <abstract language="deu">Gezeigt wird die Miniaturisierung eines Messsystems für Oberflächenplasmonenresonanzspektroskopie (SPR), einer markierungs-, sowie zerstörungsfreien als auch hoch sensitiven Technologie. Aufgrund der hohen Kosten klassischer SPR-Geräte wird sie bisher jedoch vornehmlich in der Bio- und Medizintechnik eingesetzt. Das Messprinzip ermöglicht die Erfassung von Brechungsindexänderungen nahe einer Oberfläche. Der Transfer dieser Technologie von Laborgeräten hin zu einem miniaturisierten Sensorsystem senkt die Kosten, macht das System robuster und ermöglicht so ein wesentlich breiteres Anwendungsspektrum. Ein sehr vielversprechendes Merkmal des hier vorgestellten Systems ist die Möglichkeit den SPR-Effekt winkelabhängig zur Lichtquelle ohne bewegliche Bauteile zu verfolgen.&#13;
&#13;
The miniaturization of Surface Plasmon Resonance (SPR) technology, which mainly finds its applications in pharmaceutical screening and biotechnology so far, is described. SPR spectroscopy is a label-free, non destructive and highly sensitive measurement principle which is capable of detecting changes in the refractive index in striking distance to a gold surface. A transfer of this technology to a miniaturized sensor will broaden the range of possible applications. A promising feature which is included in the miniaturized system is the angle-dependent recording of the SPR signals without moving parts.</abstract>
    <parentTitle language="deu">MikroSystemTechnik Kongress 2017 : MEMS, Mikroelektronik, Systeme 23.-25. Oktober 2017 in München</parentTitle>
    <identifier type="isbn">978-3-8007-4491-6</identifier>
    <enrichment key="opus.source">publish</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Peter Hausler</author>
    <author>Christa Genslein</author>
    <author>Carina Roth</author>
    <author>Thomas Hirsch</author>
    <author>Rudolf Bierl</author>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Bewegungselement</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Biotechnik</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Brechungsindex</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Goldoberfläche</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Laborgerät</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Lichtquelle</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Medizintechnik</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Messprinzip</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Messsystem</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Miniaturisierung</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Oberflächenplasmon</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Oberflächenplasmonenresonanzspektroskopie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>pharmazeutisches Screening</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Sensorsystem</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Spektroskopie</value>
    </subject>
    <collection role="ddc" number="621">Angewandte Physik</collection>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1436</id>
    <completedYear/>
    <publishedYear>2017</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue>1008001F</issue>
    <volume>10080</volume>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2017-02-17</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Detection of small molecules with surface plasmon resonance by synergistic plasmonic effects of nanostructured surfaces and graphene</title>
    <abstract language="eng">Surface plasmon resonance depends on the dielectric medium at the vicinity and makes it a quasi-universal detector. Therefore, and due to the label-free nature, SPR is a widely used sensing tool for real‐time monitoring molecular interactions of various analytes. However, detection of highly diluted analytes and small molecules (&lt; 400 Da) is still challenging. Gold nanohole arrays provide plasmonic hotspots with improved surface sensitivity and 2D carbon nanomaterials enable binding near the surface. Both effects together are promising in the development of SPR sensors for the efficient determination of small molecules. Graphene is known for efficient binding of molecules with delocalized aromatic π-systems. Additionally, the electromagnetic field is locally enhanced and modulated by the interaction of graphene photonics with the plasmonics of metal nanostructures. The advantages of chemical vapor deposition (CVD) graphene over reduced graphene oxide (rGO) is illustrated by a proof of concept study. In comparison to substrates consisting of a continuous film the surface sensitivity is enhanced for a nanohole arrays and further improved for CVD graphene functionalization in contrast to rGO. The feasibility of the sensor was demonstrated for the detection of adenine down to a concentration of 0.9 μM.</abstract>
    <parentTitle language="eng">SPIE Proceedings, Plasmonics in Biology and Medicine XIV, 2017, San Francisco, California</parentTitle>
    <identifier type="doi">10.1117/12.2252256</identifier>
    <enrichment key="opus.source">publish</enrichment>
    <author>Christa Genslein</author>
    <author>Peter Hauser</author>
    <author>Eva-Maria Kirchner</author>
    <author>Rudolf Bierl</author>
    <author>Antje J. Baeumner</author>
    <author>Thomas Hirsch</author>
    <collection role="ddc" number="621">Angewandte Physik</collection>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1560</id>
    <completedYear/>
    <publishedYear>2015</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2021-03-21</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">High integrated miniaturized sensor based on Surface Plasmon Resonance</title>
    <parentTitle language="eng">International Biosensor Conference, 11th Workshop on Biosensors &amp; Bioanalytical Microtechniques in Environmental, Food &amp; Clinical Analysis, BBMEC 11, 26.-30. September 2015, Regensburg, Germany</parentTitle>
    <enrichment key="opus.source">publish</enrichment>
    <author>Peter Hausler</author>
    <author>Sven Holler</author>
    <author>Thomas Hirsch</author>
    <author>Rudolf Bierl</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>1451</id>
    <completedYear/>
    <publishedYear>2015</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>VDE Verlag</publisherName>
    <publisherPlace>Berlin</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>2015-10-28</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Miniaturisierte Oberflächenplasmonenresonanz Sensorplattform</title>
    <parentTitle language="deu">MEMS, Mikroelektronik, Systeme, MikroSystemTechnik Kongress 2015, 26.- 28. Oktober 2015, Karlsruhe, proceedings</parentTitle>
    <identifier type="isbn">978-3-8007-4100-7</identifier>
    <enrichment key="opus.source">publish</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Peter Hausler</author>
    <author>Sven Holler</author>
    <author>Thomas Hirsch</author>
    <author>Rudolf Bierl</author>
    <collection role="ddc" number="621">Angewandte Physik</collection>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>5937</id>
    <completedYear/>
    <publishedYear>2023</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1</pageFirst>
    <pageLast>12</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>30</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">A sub-ppbv-level Acetone and Ethanol Quantum Cascade Laser Based Photoacoustic Sensor– Characterization and Multi-Component Spectra Recording in Synthetic Breath</title>
    <abstract language="eng">Trace gas analysis in breath is challenging due to the vast number of different components. We present a highly sensitive quantum cascade laser based photoacoustic setup for breath analysis. Scanning the range between 8263 and 8270 nm with a spectral resolution of 48 pm, we are able to quantify acetone and ethanol within a typical breath matrix containing water and CO2. We photoacoustically acquired spectra within this region of mid-infra-red light and prove that those spectra do not suffer from non-spectral interferences. The purely additive behavior of a breath sample spectrum was verified by comparing it with the independently acquired single component spectra using Pearson and Spearman correlation coefficients. A previously presented simulation approach is improved and an error attribution study is presented. With a 3σ detection limit of 6.5 ppbv in terms of ethanol and 250 pptv regarding acetone, our system is among the best performing presented so far.</abstract>
    <parentTitle language="eng">Photoacoustics</parentTitle>
    <identifier type="doi">10.1016/j.pacs.2023.100473</identifier>
    <identifier type="issn">2213-5979</identifier>
    <note>Corresponding author: Jonas Pangerl</note>
    <enrichment key="opus.import.date">2023-04-11T12:12:35+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <enrichment key="CorrespondingAuthor">Jonas Pangerl</enrichment>
    <enrichment key="opus.doi.autoCreate">false</enrichment>
    <enrichment key="opus.urn.autoCreate">false</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Jonas Pangerl</author>
    <author>Elisabeth Moser</author>
    <author>Max Müller</author>
    <author>Stefan Weigl</author>
    <author>Simon Jobst</author>
    <author>Thomas Rück</author>
    <author>Rudolf Bierl</author>
    <author>Frank-Michael Matysik</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Acetone</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Breath analysis</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Photoacoustic spectroscopy</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Quantum cascade laser</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Spectral simulation</value>
    </subject>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="oaweg" number="">Gold Open Access- Erstveröffentlichung in einem/als Open-Access-Medium</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="oaweg" number="">Corresponding author der OTH Regensburg</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>2319</id>
    <completedYear/>
    <publishedYear>2020</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>395</pageFirst>
    <pageLast>396</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>patent</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Method and System for Evaluating a Structural Integrity of an Aerial Vehicle</title>
    <parentTitle language="deu">Europäisches Patentblatt (09.12.2020) zur Anmeldung: OTH Regensburg, Anmeldenummer: 19179054.2, Patentnummer 1001/3748327, Veröffentlichungsnummer: 3 748 327</parentTitle>
    <enrichment key="opus.import.date">2022-01-14T10:19:11+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="PatentNr">1001/3748327</enrichment>
    <enrichment key="PatentYear">2020</enrichment>
    <enrichment key="PatentDate">04.05.2020</enrichment>
    <author>Florian Olbrich</author>
    <author>Christian Pongratz</author>
    <author>Rudolf Bierl</author>
    <author>Ingo Ehrlich</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="institutes" number="FAKMB">Fakultät Maschinenbau</collection>
    <collection role="persons" number="ehrlichlft">Ehrlich, Ingo (Prof. Dr.) - Labor Faserverbundtechnik</collection>
    <collection role="persons" number="tcnehno">Technologie-Campus Neustadt a. d. Donau (Prof. Ehrlich+ Prof. Nonn)</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Labor Faserverbundtechnik (LFT)</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>3404</id>
    <completedYear/>
    <publishedYear>2021</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>Dt. Gesellschaft für angewandte Optik</publisherName>
    <publisherPlace>Erlangen-Nürnberg</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Miniaturisierte Sensoren basierend auf Oberflächenplasmonenresonanz, Chancen und Herausforderungen</title>
    <abstract language="deu">Derzeit gibt es zahlreiche Bereiche, wie Umwelt Monitoring und zivile Infrastruktur in denen geeignete Sensoren für die Überwachung der Systeme fehlen. SPR-basierte Sensoren haben das Potential diese Lücke zu schließen. Um für den Einsatz in der Umwelt tauglich zu werden, müssen die Sensoren noch robuster werden. Hier wird eine mögliche Lösung gezeigt.</abstract>
    <parentTitle language="deu">DGaO-Proceedings 2021</parentTitle>
    <identifier type="url">https://www.dgao-proceedings.de/download/122/122_a21.pdf</identifier>
    <enrichment key="opus.import.date">2022-04-08T17:03:27+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Peter Hausler</author>
    <author>Johannes Fischer</author>
    <author>Lukas Wunderlich</author>
    <author>Patrick Recum</author>
    <author>Sebastian Peller</author>
    <author>Thomas Hirsch</author>
    <author>Rudolf Bierl</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>4993</id>
    <completedYear/>
    <publishedYear>2022</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue>September</issue>
    <volume>122</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">A Deep Learning System to Transform Cross-Section Spectra to Varying Environmental Conditions</title>
    <abstract language="eng">Absorption cross-sections provide a basis for many gas sensing applications. Therefore, any error in molecular cross-sections caused by varying environmental conditions propagates to spectroscopic applications. Original molecular cross-sections in varying environmental conditions can only be simulated for some molecules, whereas for most multi-atom molecules, one must rely on high-precision measurements at certain environmental configurations. In this study, a deep learning system trained with simulated absorption cross-sections for predicting cross-sections at a different pressure configuration is presented. The system’s capability to transfer to measured, multi-atom cross-sections is demonstrated. Thus, it provides an alternative to (pseudo-) line lists whenever the required information for simulation is unavailable. The predictive performance of the system was evaluated on validation data via simulation, and its transfer learning capabilities were demonstrated on actual measurement chlorine nitrate data. From the comparison between the system and line lists, the system shows slightly worse performance than pseudo-line lists but its predictive quality is still deemed acceptable with less than 5% relative integral change with a highly localized error around the peak center. This opens a promising way for further research to use deep learning to simulate the effect of varying environmental conditions on absorption cross-sections.</abstract>
    <parentTitle language="eng">Vibrational Spectroscopy</parentTitle>
    <identifier type="doi">10.1016/j.vibspec.2022.103410</identifier>
    <identifier type="issn">0924-2031</identifier>
    <enrichment key="opus.import.date">2022-07-21T22:59:47+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Elisabeth Moser</author>
    <author>Simon Jobst</author>
    <author>Rudolf Bierl</author>
    <author>Frank Jenko</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Spectroscopy</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Deep learning</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Simulation</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Pressure broadening</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Pseudo-line lists</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Transfer learning</value>
    </subject>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>5456</id>
    <completedYear/>
    <publishedYear>2022</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>Optica Publishing Group</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Modeling the Photoacoustic Spectrum of a Quantum Cascade Laser for Human Breath</title>
    <abstract language="eng">A modeling approach to create a photoacoustic spectrum from synthetic data is presented and evaluated. The resulting model reaches a MAPE score of 2.7% and can be used to enable data-driven development in future work.</abstract>
    <parentTitle language="eng">Optical Sensors and Sensing Congress 2022 (AIS, LACSEA, Sensors, ES): July 11 - 15, 2022, Vancouver, British Columbia Canada</parentTitle>
    <identifier type="doi">10.1364/AIS.2022.ATu3G.2</identifier>
    <identifier type="isbn">978-1-957171-10-4</identifier>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Elisabeth Moser</author>
    <author>Jonas Pangerl</author>
    <author>Simon Jobst</author>
    <author>Stefan Weigl</author>
    <author>Rudolf Bierl</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Quantenkaskadenlaser</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Photoakustische Spektrometrie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Atemluft</value>
    </subject>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>6462</id>
    <completedYear/>
    <publishedYear>2023</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition>Online veröffentlicht</edition>
    <issue/>
    <volume/>
    <type>article</type>
    <publisherName>Oldenbourg Wissenschaftsverlag</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Improving the performance of artificial neural networks trained on synthetic data in gas spectroscopy – a study on two sensing approaches</title>
    <abstract language="eng">Artificial neural networks (ANNs) are used in quantitative infrared gas spectroscopy to predict concentrations on multi-component absorption spectra. Training of ANNs requires vast amounts of labelled training data which may be elaborate and time consuming to obtain. Additional data can be gained by the utilization of synthetically generated spectra, but at the cost of systematic deviations to measured data. Here, we present two approaches to train ANNs with a combination of comparatively small, measured data sets and synthetically generated data. For the first approach a neural network is trained hybridly with synthetically generated infrared absorption spectra of mixtures of N2O and CO and measured zero-gas spectra, taken with a mid-infrared dual comb spectrometer. This improves the mean absolute error (MAE) of the network predictions from 0.46 to 0.01 ppmV and 0.24 to 0.01 ppmV for the concentration predictions of N2O and CO respectively for zero-gas measurements which was previously observed for training with purely synthetic data. At the same time a similar performance on spectra from gas mixtures of 0–100 ppmV N2O and 0 to 60 ppmV CO was achieved. For the second approach an ANN pre-trained on synthetic infrared spectra of mixtures of acetone and ethanol is retrained on a small dataset consisting of 26 spectra taken with a mid-infrared photoacoustic spectrometer. In this case the MAE for the concentration predictions of ethanol and acetone are improved by 45 % and 20 % in comparison to purely synthetic training. This shows the capability of using synthetically generated data to train ANNs in combination with small amounts of measured data to further improve neural networks for gas sensing and the transferability between different sensing approaches.</abstract>
    <abstract language="deu">Künstliche neuronale Netze werden in der quantitativen Infrarot-Gasspektroskopie eingesetzt, um Gaskonzentrationen in Multi-Komponenten-Absorptionsspektren vorherzusagen. Das Training von künstlichen neuronalen Netzen benötigt große Mengen an Trainingsdaten, was mit einem hohen Arbeits- und Zeitaufwand verbunden ist. Zusätzliche Trainingsdaten können durch synthetisch generierte Spektren gewonnen werden, sind jedoch mit systematischen Abweichungen zu tatsächlich gemessenen Daten verbunden. In dieser Arbeit werden zwei Ansätze präsentiert, um künstliche neuronale Netze mit einer Kombination aus vergleichsweise kleinen, gemessenen Datensätzen und synthetisch erzeugten Daten zu trainieren. Für den ersten Ansatz wird das neuronale Netz hybrid mit synthetisch erzeugten Infrarot-Absorptionsspektren von Mischungen aus N2O und CO und gemessenen Null-Gas-Spektren trainiert, welche mit einem Doppel-Kamm-Spektrometer im Mittelinfraroten aufgenommen wurden. Dieses Vorgehen verbessert den mittleren, absoluten Fehler der Netzvorhersagen von 0,46 auf 0,01 ppmV und 0,24 auf 0,01 ppmV für N2O bzw. für CO für Null-Gas-Messungen, im Vergleich zu den Vorhersagen des neuronalen Netzes, welches nur mit synthetisch erzeugten Daten trainiert wurde. Gleichzeitig zeigte das hybrid trainierte Netz eine gleichbleibende Performance für Konzentrationsvorhersagen für Spektren aus Gasmischungen von 0 bis 100 ppmV N2O und 0 bis 60 ppmV CO. Für den zweiten Ansatz wird ein neuronales Netz, welches bereits mit synthetischen erzeugten Infrarotspektren von Mischungen aus Aceton und Ethanol trainiert wurde, erneut auf einem kleinen gemessenen Datensatz bestehend aus 26 Spektren trainiert, welche mit einem photoakustischen Spektrometer im mittleren Infrarot aufgenommen wurden. In diesem Fall hat sich der mittlere absolute Fehler der Konzentrationsvorhersage für Ethanol und Aceton um 45 % bzw. 20 % im Vergleich zu einem rein synthetischen Training verbessert. Das zeigt das Potential synthetisch erzeugte Daten für das Training von künstlichen neuronalen Netzen in Kombination mit kleinen gemessenen Datensätzen zu nutzen, um neuronale Netze für den Einsatz im Bereich der Gassensorik zu verbessern und gleichzeitig die Übertragbarkeit der Methodik auf verschiedene Messansätze.</abstract>
    <parentTitle language="eng">tm - Technisches Messen</parentTitle>
    <identifier type="doi">10.1515/teme-2023-0051</identifier>
    <enrichment key="opus.import.date">2023-08-21T08:29:45+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <enrichment key="opus.doi.autoCreate">false</enrichment>
    <enrichment key="opus.urn.autoCreate">true</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Jens Goldschmidt</author>
    <author>Elisabeth Moser</author>
    <author>Leonard Nitzsche</author>
    <author>Rudolf Bierl</author>
    <author>Jürgen Wöllenstein</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>6534</id>
    <completedYear/>
    <publishedYear>2023</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>228</pageFirst>
    <pageLast>233</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>IEEE</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Luminance Simulation in CARLA under Cloud Coverage - Model Validation and Implications</title>
    <abstract language="eng">To decrease the number of kilometers driven during the development of autonomous cars or driving assistance systems, performant simulation tools are necessary. Currently, domain distance effects between simulation and reality are limiting the successful application of rendering engines in data-driven perception tasks. In order to mitigate those domain distance effects, simulation tools have to be as close to reality as possible for the given task. For optical sensors like cameras, the luminance of the scene is essential. We provide within this paper a method to measure the luminance of rendered scenes within CARLA, an often used open-source simulation environment. Thereby, it is possible to validate the environment and weather models by taking real-world measurements with photometric sensors or with the help of open-source weather data, published e.g. by the German federal service for weather data (DWD - "Deutscher Wetterdienst"). Employing our proposed luminance measurement, the domain gap resulting from the simulation can be specified, which makes it possible to evaluate the statements about the safety of the automated driving system determined within the simulation. We show that the ratio between global and diffuse radiation modeled by the default atmosphere models within CARLA are under limited conditions similar to real-world measurements taken by the DWD. Nevertheless, we show, that the ratio’s temporal variability in real-world situations is not modeled by CARLA.</abstract>
    <parentTitle language="eng">2023 IEEE International Workshop on Metrology for Automotive (MetroAutomotive), -30 June 2023, Modena, Italy</parentTitle>
    <identifier type="isbn">979-8-3503-2187-6</identifier>
    <identifier type="doi">10.1109/MetroAutomotive57488.2023.10219098</identifier>
    <enrichment key="opus.import.date">2023-10-16T20:23:06+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <enrichment key="opus.doi.autoCreate">false</enrichment>
    <enrichment key="opus.urn.autoCreate">true</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Fabian Ulreich</author>
    <author>Elisabeth Moser</author>
    <author>Florian Olbrich</author>
    <author>Martin Ebert</author>
    <author>Rudolf Bierl</author>
    <author>André Kaup</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Atmospheric measurements</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Atmospheric modeling</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Cameras</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>carla</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Cloud computing</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>cloud coverage</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Data models</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>luminance</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>meteorology</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Simulation</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Soft sensors</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>weather</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Wind</value>
    </subject>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>6548</id>
    <completedYear/>
    <publishedYear>2023</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>4263</pageFirst>
    <pageLast>4270</pageLast>
    <pageNumber/>
    <edition/>
    <issue>18</issue>
    <volume>16</volume>
    <type>article</type>
    <publisherName>Copernicus Publications</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Comparison of photoacoustic spectroscopy and cavity ring-down spectroscopy for ambient methane monitoring at Hohenpeißenberg</title>
    <abstract language="eng">With an atmospheric concentration of approximately 2000 parts per billion (ppbV, 10−9), methane (CH4) is the second most abundant greenhouse gas (GHG) in the atmosphere after carbon dioxide (CO2). The task of long-term and spatially resolved GHG monitoring to verify whether climate policy actions are effective is becoming more crucial as climate change progresses. In this paper we report the CH4 concentration readings of our photoacoustic (PA) sensor over a 5 d period at Hohenpeißenberg, Germany. As a reference device, a calibrated cavity ring-down spectrometer, Picarro G2301, from the meteorological observatory of the German Weather Service (DWD) was employed. Trace gas measurements with photoacoustic instruments promise to provide low detection limits at comparably low costs. However, PA devices are often susceptible to cross-sensitivities related to fluctuating environmental conditions, e.g. ambient humidity. The obtained results show that for PA sensor systems non-radiative relaxation effects induced by varying humidity are a non-negligible factor. Applying algorithm compensation techniques, which are capable of calculating the influence of non-radiative relaxation effects on the photoacoustic signal, increase the accuracy of the photoacoustic sensor significantly. With an average relative deviation of 1.11 % from the G2301, the photoacoustic sensor shows good agreement with the reference instrument.</abstract>
    <parentTitle language="eng">Atmospheric Measurement Techniques</parentTitle>
    <identifier type="doi">10.5194/amt-16-4263-2023</identifier>
    <identifier type="issn">1867-8548</identifier>
    <enrichment key="opus.import.date">2023-10-16T20:23:06+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Max Müller</author>
    <author>Stefan Weigl</author>
    <author>Jennifer Müller-Williams</author>
    <author>Matthias Lindauer</author>
    <author>Thomas Rück</author>
    <author>Simon Jobst</author>
    <author>Rudolf Bierl</author>
    <author>Frank-Michael Matysik</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="oaweg" number="">Gold Open Access- Erstveröffentlichung in einem/als Open-Access-Medium</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="oaweg" number="">Corresponding author der OTH Regensburg</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>6146</id>
    <completedYear/>
    <publishedYear>2022</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>preprint</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">A Highly Sensitive Acetone and Ethanol Quantum Cascade Laser Based Photoacoustic Sensor: Characterization and Multi-Component Spectra Recording in Synthetic Breath</title>
    <abstract language="eng">Trace gas analysis in breath is challenging due to the vast number of different components. We present a highly sensitive quantum cascade laser based photoacoustic setup for breath analysis. Scanning the range between 8260 and 8270 nm with a spectral resolution of 48 pm, we are able to quantify acetone and ethanol within a typical breath matrix containing water and CO2. We photoacoustically acquired spectra within this region of mid-infra-red light and prove that those spectra do not suffer from non-spectral interferences. The purely additive behavior of a breath sample spectrum was verified by comparing it with the independently acquired single component spectra using Pearson and Spearman correlation coefficients. A previously presented simulation approach is improved and an error attribution study is presented. With a 3σ detection limit of 6.5 ppbV in terms of ethanol and 250 pptV regarding acetone, our system is among the best performing presented so far.</abstract>
    <parentTitle language="eng">SSRN Electronic Journal</parentTitle>
    <identifier type="doi">10.2139/ssrn.4305376</identifier>
    <enrichment key="CorrespondingAuthor">Jonas Pangerl</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Jonas Pangerl</author>
    <author>Elisabeth Moser</author>
    <author>Max Müller</author>
    <author>Stefan Weigl</author>
    <author>Simon Jobst</author>
    <author>Thomas Rück</author>
    <author>Rudolf Bierl</author>
    <author>Frank-Michael Matysik</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Photoacoustic spectroscopy</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>quantum cascade laser</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>spectral simulation</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>breath analysis</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>acetone</value>
    </subject>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>7038</id>
    <completedYear/>
    <publishedYear>2024</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>patent</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2024-02-19</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Method and System for Evaluating a Structural Integrity of an Aerial Vehicle</title>
    <enrichment key="PatentNr">US 11,835,425 B2</enrichment>
    <enrichment key="PatentLand">Vereinigten Staaten von Amerika</enrichment>
    <enrichment key="PatentYear">2020</enrichment>
    <enrichment key="PatentDate">04.06.2020</enrichment>
    <enrichment key="PatentZugriff">United States Patent</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Florian Olbrich</author>
    <author>Christian Pongratz</author>
    <author>Rudolf Bierl</author>
    <author>Ingo Ehrlich</author>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="institutes" number="FAKMB">Fakultät Maschinenbau</collection>
    <collection role="institutes" number="TCNeustadt">Technologie-Campus Neustadt an der Donau</collection>
    <collection role="persons" number="ehrlichlft">Ehrlich, Ingo (Prof. Dr.) - Labor Faserverbundtechnik</collection>
    <collection role="persons" number="tcnehno">Technologie-Campus Neustadt a. d. Donau (Prof. Ehrlich+ Prof. Nonn)</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
  </doc>
  <doc>
    <id>8088</id>
    <completedYear/>
    <publishedYear>2023</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1</pageFirst>
    <pageLast>3</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>IEEE</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Fast sound field characterization of beamforming capable capacitive micromachined ultrasonic transducer (CMUT) arrays by refracto-vibrometry</title>
    <abstract language="eng">We introduce a time-optimized setup based on refracto-vibrometry for the purpose of scanning the sound field of capacitive micromachined ultrasonic transducer (CMUT) arrays primarily for the qualification of their beamforming capability. In comparison to commonly used microphones on a traversing stage the proposed method is substantially faster and consumes only a few minutes of time for a complete two-dimensional sound field containing about 100.000 scan points.</abstract>
    <parentTitle language="eng">IEEE IUS 2023, International Ultrasonics Symposium, Montréal, September 3-8, 2023</parentTitle>
    <additionalTitle language="deu">Schnelle Schallfeld-Charakterisierung von CMUT-Arrays mithilfe von Refrakto-Vibrometrie</additionalTitle>
    <identifier type="isbn">979-8-3503-4645-9</identifier>
    <identifier type="issn">1948-5727</identifier>
    <identifier type="doi">10.1109/IUS51837.2023.10308126</identifier>
    <enrichment key="local_import_origin">crossref</enrichment>
    <enrichment key="Kostentraeger">2098031</enrichment>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Sebastian Peller</author>
    <author>Tobias Zankl</author>
    <author>Christoph Fischer</author>
    <author>Rudolf Bierl</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>CMUT</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>LDV</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>refracto-vibrometry</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>sound field</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>beamforming</value>
    </subject>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
  </doc>
  <doc>
    <id>4657</id>
    <completedYear/>
    <publishedYear>2017</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst>848</pageFirst>
    <pageLast>850</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>VDE-Verlag</publisherName>
    <publisherPlace>München</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Einbindung eines 2D-Photodetektors in einen hochintegrierten SPR-Imaging-Sensor</title>
    <abstract language="deu">Die Oberflächenplasmonenresonanzspektroskopie (SPR) ist eine hochempfindliche Messmethode, die es erlaubt, Gase und Flüssigkeiten zerstörungs- und markierungsfrei in Echtzeit zu analysieren. Bisher vornehmlich im Labormaßstab in der Bioanalytik und dem Wirkstoffscreening eingesetzt, soll diese Technologie nun miniaturisiert und für weitere Anwendungsgebiete zugänglich gemacht werden. Dazu wird ein kompakter Micro-Opto-Electro-Mechanical Systems Sensor (MOEMS) entwickelt, der mit Hilfe des SPR Imaging Änderungen der chemischen Zusammensetzung verschiedener Flüssigkeiten inline messen kann.</abstract>
    <abstract language="eng">Surface plasmon resonance spectroscopy (SPR) is a highly sensitive measurement method which allows the analysis of gases and liquids in real-time in a non-destructive and marking-free manner. Presently SPR is predominantly used for pharmaceutical screening and biotechnical analysis. Now this technology is to be miniaturized and made accessible for further application areas. For this purpose, a compact micro-opto-electro-mechanical system sensor (MOEMS) is developed, which can measure changes in the chemical composition of different fluids using SPR imaging.</abstract>
    <parentTitle language="deu">7. MikroSystemTechnik Kongress "MEMS, Mikroelektronik, Systeme", 23.-25. Oktober 2017, München</parentTitle>
    <additionalTitle language="eng">Integration of a 2D-photodetector in a SPR-Imaging-Sensor</additionalTitle>
    <identifier type="isbn">978-3-8007-4491-6</identifier>
    <enrichment key="opus.import.date">2022-07-03T14:30:54+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Carina Roth</author>
    <author>Peter Hausler</author>
    <author>Rudolf Bierl</author>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Bildsensor</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Bioanalytik</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>chemische Zusammensetzung</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Fotodetektor</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Labormaßstab</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Messmethode</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>mikrooptoelektromechanisches System</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Oberflächenplasmon</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Oberflächenplasmonenresonanzspektroskopie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>pharmazeutisches Screening</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Spektroskopie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Wirkstoff</value>
    </subject>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
  </doc>
  <doc>
    <id>8800</id>
    <completedYear/>
    <publishedYear>2025</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>16</pageNumber>
    <edition/>
    <issue/>
    <volume/>
    <type>preprint</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Real-time hardware-based processing of high-precision detector signals for surface plasmon resonance spectroscopy</title>
    <abstract language="eng">Surface plasmon resonance (SPR) is limited by small-signal detectability and drift when subtraction occurs in software after digitization. We introduce an SPR detector that performs on-detector amplification and analog differential readout, eliminating moving parts and software-heavy correction. The hardware-native subtraction boosts the usable ADC range and suppresses illumination and environmental noise. In fixed-angle refractive-index steps (NaCl), the platform resolves Δn_min ≈ 1.8 × 10⁻⁷ RIU compared to 4.6–7.2 × 10⁻⁶ RIU on a commercial comparator and improves small-signal SNR by up to ∼5,000-fold, while remaining competitive at high signal levels. In a model IgG–BSA assay, the detector’s low noise floor clarifies early binding and equilibrium transitions. By generating inherently clean raw signals, this hardware-native approach dramatically enhances sensitivity and long-term stability for label-free biosensing and inline process analytics while rendering AI-based or complex post-processing entirely unnecessary. The concept generalizes across platforms and opens a compact route to robust, high-fidelity SPR in complex environments, with a clear path toward multi-wavelength and arrayed detectors for high-throughput chemical monitoring.</abstract>
    <identifier type="doi">10.2139/ssrn.5971170</identifier>
    <enrichment key="opus.import.date">2026-01-12T13:58:33+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="opus.doi.autoCreate">false</enrichment>
    <enrichment key="opus.urn.autoCreate">false</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Johannes Fischer</author>
    <author>Thomas Hirsch</author>
    <author>Torsten Reitmeier</author>
    <author>Rudolf Bierl</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Drift-free SPR</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Hardware-native sensing</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Noise suppression</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>On-detector amplification</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Small-signal detection</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Surface plasmon resonance</value>
    </subject>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="institutes" number="FAKMB">Fakultät Maschinenbau</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
    <collection role="DFGFachsystematik" number="1">Ingenieurwissenschaften</collection>
    <collection role="othforschungsschwerpunkt" number="">Materialien und Produktion</collection>
  </doc>
  <doc>
    <id>6379</id>
    <completedYear/>
    <publishedYear>2021</publishedYear>
    <thesisYearAccepted>2021</thesisYearAccepted>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>xlii, 282</pageNumber>
    <edition/>
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    <type>doctoralthesis</type>
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    <completedDate>2021-02-01</completedDate>
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    <title language="eng">Development of a sensor system for human breath acetone analysis based on photoacoustic spectroscopy</title>
    <abstract language="eng">The breath analysis section of this thesis outlines the potentials but also emphasises the concomitant challenges of human breath analysis. The section further describes the usefulness of a point-of-care (POC) device for breath acetone detection. In addition, it covers various breath analysis related subjects, which can be useful considering further developments of breath analysers. This includes an extensive summary involving the high abundant endogenous as well as the exogenous breath species present in a clinical environment.&#13;
Subsequently, a detailed discussion about the theoretical aspects of absorption spectra is provided, forming the basis for the spectral interference chapter. Classical absorption spectroscopy (AS) is compared with photoacoustic spectroscopy (PAS) in view of trace gas analysis. Different modulation schemes for signal generation, i.e. amplitude modulation (AM) and wavelength modulation (WM) are part of the comparison, while the advantages and disadvantages of each technique are highlighted. As a result, PAS is considered superior to AS and hence is selected as the method of choice regarding the development of a sensor for breath acetone detection.&#13;
A detailed mathematical derivation of the photoacoustic signal generation as well as the signal enhancement by means of acoustic resonance amplification is provided. Moreover, several phenomena causing signal attenuation are outlined, including vibrational-translational (VT) relaxation, vibrational-vibrational (VV) energy transfer mechanism, acoustic detuning and photodissociation.&#13;
Various simulations regarding spectral interferences in the infra-red (IR) and ultraviolet (UV) region are presented, demonstrating the susceptibility towards spectral cross-sensitivities in the IR region, hence, rather suggesting the UV region for acetone detection. However, this simulation can be easily adopted to other target analytes and serves as a basis for multicomponent analysis approaches in the IR region using tuneable light sources.&#13;
Ultra sensitive acetone detection employing a high power UV LED is presented and a detailed analysis considering the effects of environmental parameters onto the photoacoustic signal, including temperature, pressure, LED duty cycle and flow rate, is&#13;
provided. In addition, general cross-sensitivities of the photoacoustic signal towards the high abundant species O2, CO2 and H2O have been investigated and discussed. Moreover, several LED and photoacoustic cell (PAC) combinations have been compared in order to evaluate improvement approaches regarding an enhancement of the system’s sensitivity.&#13;
Finally, photoacoustic sensor setups employing an interband cascade laser (ICL) or a&#13;
quantum cascade laser (QCL) have been studied and compared to various UV setups in view of different key performance parameters, including the limits of detection (LOD) and the normalised noise equivalent absorption (NNEA) coefficients. The juxtaposition of the different approaches once more emphasises the extraordinary sensitivity of photoacoustic spectroscopy. To the best of the author’s knowledge, the LODs (3σ) of the UV LED based photoacoustic measurement in typical breath conditions (12.5 ppbV) and the LOD of the QCL measurement (0.79 ppbV) provide two world records. First, regarding photoacoustic acetone detection using an UV LED and second, in view of other published results for photoacoustic acetone detection in general.</abstract>
    <abstract language="deu">Zu Beginn der Arbeit werden zum einen die Potentiale der Analyse des menschlichen Ausatemgases aufgezeigt und zum anderen die damit verbundenen Herausforderungen beschrieben. Dabei wird auch die Nützlichkeit eines Point-of-Care (POC) Gerätes zur Bestimmung des Acetongehalts im Ausatemgas hervorgehoben. Darüber hinaus werden verschiedene mit der Atemgasanalyse zusammenhängende Themen behandelt, die hinsichtlich weiterer Entwicklungen von Atemgasanalysegeräten sehr hilfreich sein können. Dazu gehört u.a. eine ausführliche Analyse der Zusammensetzung des menschlichen Ausatemgases, die sowohl die hauptsächlichen endogenen als auch die im klinischen Umfeld verstärkt vorkommenden, exogenen Bestandteile, aufgelistet.&#13;
Anschließend werden die theoretischen Grundlagen von Absorptionsspektren detailliert behandelt, da sie die Grundlage für das Kapitel über die spektralen Interferenzen bilden. Des Weiteren werden die klassische Absorptionsspektroskopie (AS), als auch die photoakustische Spektroskopie (PAS), hinsichtlich ihrer Eignung für die Spurengasanalytik verglichen. Verschiedene Modulationsschemata für die Signalerzeugung, d.h. Amplitudenmodulation (AM) und Wellenlängenmodulation (WM), sind Teil des Vergleichs, wobei die Vor- und Nachteile jeder Technik hervorgehoben werden. Als Ergebnis wurde die PAS gegenüber der AS als überlegen angesehen und daher als Methode der Wahl bei der Entwicklung eines Sensors zur Bestimmung des Acetongehalts in der Ausatemluft ausgewählt.&#13;
Eine detaillierte mathematische Herleitung der photoakustischen Signalerzeugung sowie der Signalverstärkung mittels akustischer Resonanzverstärkung ist ebenso in der Arbeit enthalten. Darüber hinaus werden mehrere Phänomene der Signaldämpfung skizziert, dazu zählen u.a. die Schwingungs-Translation Relaxation, der Schwinungs-Schwingungs Energieübertragungsmechanismus, die Photodissoziation und die akustische Resonanzverschiebung.&#13;
Es werden verschiedene Simulationen bezüglich spektraler Interferenzen im infraroten (IR) und ultraviolleten (UV) Wellenlängenbereich vorgestellt, die die Anfälligkeit gegenüber spektralen Querempfindlichkeiten im IR-Bereich demonstrieren und somit eher den UV-Bereich für die Acetonbestimmung nahelegen. Die Simulationsergebnisse können leicht auf weitere Zielanalyten übertragen werden und dienen somit als Grundlage für Multikomponenten-Analyseansätze im IR-Bereich mittels durchstimmbarer Lichtquellen.&#13;
Im Ergebnisteil wird u.a. ein hochempfindliches System zur Acetondetektion unter Verwendung einer Hochleistungs-UV LED vorgestellt. Dieses System wurde außerdem einer detaillierten Analyse unter Berücksichtigung der Auswirkungen von Umgebungsparametern auf das photoakustische Signal, einschließlich Temperatur, Druck,&#13;
LED-Tastverhältnis und Durchfl ussrate, unterzogen. Zusätzlich wurden Querempfi ndlichkeiten des photoakustischen Systems gegenüber den im Ausatemgas hochkonzentrierten Stoffen O2, CO2 und H2O untersucht und die Ergebnisse diskutiert.&#13;
Darüber hinaus wurden verschiedene Kombinationen von LEDs und photoakustischen Zellen verglichen, um Verbesserungsansätze hinsichtlich der Empfindlichkeit des Systems zu untersuchen.&#13;
Abschließend wurden photoakustische Sensorsysteme, die einen Interbandkaskadenlaser (ICL) oder einen Quantenkaskadenlaser (QCL) verwenden, untersucht und mit verschiedenen UV LED Systemen im Hinblick auf unterschiedliche Leistungsparameter, einschließlich der Nachweisgrenzen (NWG) und den normierten, rauschäquivalenten Absorptionskoeﬀizienten, verglichen. Die Gegenüberstellung der verschiedenen Ansätze unterstreicht einmal mehr die außerordentliche Empfindlichkeit der photoakustischen Spektroskopie. Nach bestem Wissen des Autors stellen die NWGs (3σ) der photoakustischen Messung mit einer UV LED in typischer Atemgaszusammensetzung (12.5 ppbV) und die NWG der QCL-Messungen (0.79 ppbV) zwei Weltrekorde dar. Zum einen gibt es keine Veröffentlichung hinsichtlich einer besseren, photoakustisch ermittelten NWG für Aceton mittels einer UV LED und zum anderen stellt die mit dem QCL photoakustisch gemessene NWG im Allgemeinen die beste, je veröffentlichte photoakustische NWG für Aceton dar.</abstract>
    <identifier type="doi">10.5283/epub.44776</identifier>
    <identifier type="urn">urn:nbn:de:bvb:355-epub-447768</identifier>
    <enrichment key="TitelVerleihendInstitution">Universität Regensburg, Fakultät für Chemie und Pharmazie</enrichment>
    <enrichment key="opus.doi.autoCreate">false</enrichment>
    <enrichment key="opus.urn.autoCreate">false</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Stefan Weigl</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Photoacoustic</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Breath Analysis</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Acetone</value>
    </subject>
    <collection role="institutes" number="FakANK">Fakultät Angewandte Natur- und Kulturwissenschaften</collection>
    <collection role="persons" number="bierlsappz">Bierl, Rudolf (Prof. Dr.) - Sensorik-ApplikationsZentrum</collection>
    <collection role="othforschungsschwerpunkt" number="16317">Sensorik</collection>
    <collection role="institutes" number="">Sensorik-Applikationszentrum (SappZ)</collection>
    <collection role="othpublikationsherkunft" number="">Dissertation in Kooperation</collection>
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