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  <doc>
    <id>137</id>
    <completedYear/>
    <publishedYear>2008</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1142</pageFirst>
    <pageLast>1146</pageLast>
    <pageNumber/>
    <edition/>
    <issue>6</issue>
    <volume>35</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">MR-based attenuation correction for torso-PET/MR imaging</title>
    <abstract language="eng">Purpose&#13;
MR-based attenuation correction (AC) will become an integral part of combined PET/MR systems. Here, we propose a toolbox to validate MR-AC of clinical PET/MRI data sets.&#13;
Methods&#13;
Torso scans of ten patients were acquired on a combined PET/CT and on a 1.5-T MRI system. MR-based attenuation data were derived from the CT following MR–CT image co-registration and subsequent histogram matching. PET images were reconstructed after CT- (PET/CT) and MR-based AC (PET/MRI). Lesion-to-background (L/B) ratios were estimated on PET/CT and PET/MRI.&#13;
Results&#13;
MR–CT histogram matching leads to a mean voxel intensity difference in the CT- and MR-based attenuation images of 12% (max). Mean differences between PET/MRI and PET/CT were 19% (max). L/B ratios were similar except for the lung where local misregistration and intensity transformation leads to a biased PET/MRI.&#13;
Conclusion&#13;
Our toolbox can be used to study pitfalls in MR-AC. We found that co-registration accuracy and pixel value transformation determine the accuracy of PET/MRI.</abstract>
    <parentTitle language="eng">European Journal of Nuclear Medicine and Molecular Imaging</parentTitle>
    <subTitle language="eng">pitfalls in mapping MR to CT data</subTitle>
    <identifier type="doi">10.1007/s00259-008-0734-0</identifier>
    <author>Thomas Beyer</author>
    <author>Markus Weigert</author>
    <author>Harald H. Quick</author>
    <author>Uwe Pietrzyk</author>
    <author>Florian Vogt</author>
    <author>Christoph Palm</author>
    <author>Gerald Antoch</author>
    <author>Stefan P. Müller</author>
    <author>Andreas Bockisch</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>PET/MRI</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>PET/CT</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Attenuation correction</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Kernspintomografie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Positronen-Emissions-Tomografie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Schwächung</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>153</id>
    <completedYear/>
    <publishedYear>2006</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>384P</pageFirst>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue>Suppl. 1</issue>
    <volume>47</volume>
    <type>conferencepresentation</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Towards MR-based attenuation correction for whole-body PET/MR imaging</title>
    <parentTitle language="eng">The Journal of Nuclear Medicine</parentTitle>
    <identifier type="url">http://jnm.snmjournals.org/content/47/suppl_1/384P.1.abstract</identifier>
    <author>Thomas Beyer</author>
    <author>Markus Weigert</author>
    <author>Christoph Palm</author>
    <author>Harald H. Quick</author>
    <author>Stefan P. Müller</author>
    <author>Uwe Pietrzyk</author>
    <author>Florian Vogt</author>
    <author>M.J. Martinez</author>
    <author>Andreas Bockisch</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Kernspintomografie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Positronen-Emissions-Tomografie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Bildgebendes Verfahren</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Schwächung</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>151</id>
    <completedYear/>
    <publishedYear>2007</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>A116</pageFirst>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue>2</issue>
    <volume>46</volume>
    <type>conferencepresentation</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Generation of a MRI reference data set for the validation of automatic, non-rigid image co-registration algorithms</title>
    <parentTitle language="deu">Nuklearmedizin</parentTitle>
    <author>Markus Weigert</author>
    <author>Thomas Beyer</author>
    <author>Harald H. Quick</author>
    <author>Uwe Pietrzyk</author>
    <author>Christoph Palm</author>
    <author>Stefan P. Müller</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Kernspintomografie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Referenzdaten</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Registrierung &lt;Bildverarbeitung&gt;</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Algorithmus</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>144</id>
    <completedYear/>
    <publishedYear>2007</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>A115</pageFirst>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue>2</issue>
    <volume>46</volume>
    <type>conferencepresentation</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Template for MR-based attenuation correction for whole-body PET/MR imaging</title>
    <parentTitle language="deu">Nuklearmedizin</parentTitle>
    <author>Markus Weigert</author>
    <author>Christoph Palm</author>
    <author>Harald H. Quick</author>
    <author>Stefan P. Müller</author>
    <author>Uwe Pietrzyk</author>
    <author>Thomas Beyer</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Kernspintomografie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Positronen-Emissions-Tomografie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Bildgebendes Verfahren</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Schwächung</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
</export-example>
