<?xml version="1.0" encoding="utf-8"?>
<export-example>
  <doc>
    <id>102</id>
    <completedYear/>
    <publishedYear>2018</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>203</pageFirst>
    <pageLast>213</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>96</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2019-12-18</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">A survey on Barrett's esophagus analysis using machine learning</title>
    <abstract language="eng">This work presents a systematic review concerning recent studies and technologies of machine learning for Barrett's esophagus (BE) diagnosis and treatment. The use of artificial intelligence is a brand new and promising way to evaluate such disease. We compile some works published at some well-established databases, such as Science Direct, IEEEXplore, PubMed, Plos One, Multidisciplinary Digital Publishing Institute (MDPI), Association for Computing Machinery (ACM), Springer, and Hindawi Publishing Corporation. Each selected work has been analyzed to present its objective, methodology, and results. The BE progression to dysplasia or adenocarcinoma shows a complex pattern to be detected during endoscopic surveillance. Therefore, it is valuable to assist its diagnosis and automatic identification using computer analysis. The evaluation of the BE dysplasia can be performed through manual or automated segmentation through machine learning techniques. Finally, in this survey, we reviewed recent studies focused on the automatic detection of the neoplastic region for classification purposes using machine learning methods.</abstract>
    <parentTitle language="eng">Computers in Biology and Medicine</parentTitle>
    <identifier type="doi">10.1016/j.compbiomed.2018.03.014</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Luis Antonio de Souza Jr.</author>
    <author>Christoph Palm</author>
    <author>Robert Mendel</author>
    <author>Christian Hook</author>
    <author>Alanna Ebigbo</author>
    <author>Andreas Probst</author>
    <author>Helmut Messmann</author>
    <author>Silke A. T. Weber</author>
    <author>João Paulo Papa</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Speiseröhrenkrankheit</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Mustererkennung</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Lernen</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Literaturbericht</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Barrett's esophagus</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Machine learning</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Adenocarcinoma</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Image processing</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Pattern recognition</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Computer-aided diagnosis</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCBE">Regensburg Center of Biomedical Engineering - RCBE</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>354</id>
    <completedYear/>
    <publishedYear>2019</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1616</pageFirst>
    <pageLast>1623</pageLast>
    <pageNumber/>
    <edition/>
    <issue>12</issue>
    <volume>07</volume>
    <type>article</type>
    <publisherName>Georg Thieme Verlag</publisherName>
    <publisherPlace>Stuttgart</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2020-04-22</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">A technical review of artificial intelligence as applied to gastrointestinal endoscopy: clarifying the terminology</title>
    <abstract language="eng">The growing number of publications on the application of artificial intelligence (AI) in medicine underlines the enormous importance and potential of this emerging field of research.&#13;
&#13;
In gastrointestinal endoscopy, AI has been applied to all segments of the gastrointestinal tract most importantly in the detection and characterization of colorectal polyps. However, AI research has been published also in the stomach and esophagus for both neoplastic and non-neoplastic disorders.&#13;
&#13;
The various technical as well as medical aspects of AI, however, remain confusing especially for non-expert physicians.&#13;
&#13;
This physician-engineer co-authored review explains the basic technical aspects of AI and provides a comprehensive overview of recent publications on AI in gastrointestinal endoscopy. Finally, a basic insight is offered into understanding publications on AI in gastrointestinal endoscopy.</abstract>
    <parentTitle language="eng">Endoscopy International Open</parentTitle>
    <identifier type="doi">10.1055/a-1010-5705</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Creative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International</licence>
    <author>Alanna Ebigbo</author>
    <author>Christoph Palm</author>
    <author>Andreas Probst</author>
    <author>Robert Mendel</author>
    <author>Johannes Manzeneder</author>
    <author>Friederike Prinz</author>
    <author>Luis Antonio de Souza Jr.</author>
    <author>João Paulo Papa</author>
    <author>Peter Siersema</author>
    <author>Helmut Messmann</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Lernen</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Gastroenterologie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Künstliche Intelligenz</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Barrett's esophagus</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Deep learning</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="ddc" number="6">Technik, Medizin, angewandte Wissenschaften</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCHST">Regensburg Center of Health Sciences and Technology - RCHST</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="oaweg" number="">Gold Open Access- Erstveröffentlichung in einem/als Open-Access-Medium</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>353</id>
    <completedYear/>
    <publishedYear>2020</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>615</pageFirst>
    <pageLast>616</pageLast>
    <pageNumber/>
    <edition/>
    <issue>4</issue>
    <volume>69</volume>
    <type>article</type>
    <publisherName>BMJ</publisherName>
    <publisherPlace>London</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2020-04-22</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Real-time use of artificial intelligence in the evaluation of cancer in Barrett’s oesophagus</title>
    <abstract language="eng">Based on previous work by our group with manual annotation of visible Barrett oesophagus (BE) cancer images, a real-time deep learning artificial intelligence (AI) system was developed. While an expert endoscopist conducts the endoscopic assessment of BE, our AI system captures random images from the real-time camera livestream and provides a global prediction (classification), as well as a dense prediction (segmentation) differentiating accurately between normal BE and early oesophageal adenocarcinoma (EAC). The AI system showed an accuracy of 89.9% on 14 cases with neoplastic BE.</abstract>
    <parentTitle language="eng">Gut</parentTitle>
    <identifier type="doi">10.1136/gutjnl-2019-319460</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Alanna Ebigbo</author>
    <author>Robert Mendel</author>
    <author>Andreas Probst</author>
    <author>Johannes Manzeneder</author>
    <author>Friederike Prinz</author>
    <author>Luis Antonio de Souza Jr.</author>
    <author>João Paulo Papa</author>
    <author>Christoph Palm</author>
    <author>Helmut Messmann</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Speiseröhrenkrankheit</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Lernen</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Barrett's esophagus</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Deep learning</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>real-time</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="ddc" number="6">Technik, Medizin, angewandte Wissenschaften</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCHST">Regensburg Center of Health Sciences and Technology - RCHST</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="oaweg" number="">Gold Open Access- Erstveröffentlichung in einem/als Open-Access-Medium</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>680</id>
    <completedYear/>
    <publishedYear>2021</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>878</pageFirst>
    <pageLast>883</pageLast>
    <pageNumber/>
    <edition/>
    <issue>09</issue>
    <volume>53</volume>
    <type>article</type>
    <publisherName>Thieme</publisherName>
    <publisherPlace>Stuttgart</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2020-11-28</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Endoscopic prediction of submucosal invasion in Barrett’s cancer with the use of Artificial Intelligence: A pilot Study</title>
    <abstract language="eng">Background and aims: The accurate differentiation between T1a and T1b Barrett’s cancer has both therapeutic and prognostic implications but is challenging even for experienced physicians. We trained an Artificial Intelligence (AI) system on the basis of deep artificial neural networks (deep learning) to differentiate between T1a and T1b Barrett’s cancer white-light images. &#13;
&#13;
Methods: Endoscopic images from three tertiary care centres in Germany were collected retrospectively. A deep learning system was trained and tested using the principles of cross-validation. A total of 230 white-light endoscopic images (108 T1a and 122 T1b) was evaluated with the AI-system. For comparison, the images were also classified by experts specialized in endoscopic diagnosis and treatment of Barrett’s cancer. &#13;
&#13;
Results: The sensitivity, specificity, F1 and accuracy of the AI-system in the differentiation between T1a and T1b cancer lesions was 0.77, 0.64, 0.73 and 0.71, respectively. There was no statistically significant difference between the performance of the AI-system and that of human experts with sensitivity, specificity, F1 and accuracy of 0.63, 0.78, 0.67 and 0.70 respectively. &#13;
&#13;
Conclusion: This pilot study demonstrates the first multicenter application of an AI-based system in the prediction of submucosal invasion in endoscopic images of Barrett’s cancer. AI scored equal to international experts in the field, but more work is necessary to improve the system and apply it to video sequences and in a real-life setting. Nevertheless, the correct prediction of submucosal invasion in Barret´s cancer remains challenging for both experts and AI.</abstract>
    <parentTitle language="eng">Endoscopy</parentTitle>
    <identifier type="doi">10.1055/a-1311-8570</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Alanna Ebigbo</author>
    <author>Robert Mendel</author>
    <author>Tobias Rückert</author>
    <author>Laurin Schuster</author>
    <author>Andreas Probst</author>
    <author>Johannes Manzeneder</author>
    <author>Friederike Prinz</author>
    <author>Matthias Mende</author>
    <author>Ingo Steinbrück</author>
    <author>Siegbert Faiss</author>
    <author>David Rauber</author>
    <author>Luis Antonio de Souza Jr.</author>
    <author>João Paulo Papa</author>
    <author>Pierre Deprez</author>
    <author>Tsuneo Oyama</author>
    <author>Akiko Takahashi</author>
    <author>Stefan Seewald</author>
    <author>Prateek Sharma</author>
    <author>Michael F. Byrne</author>
    <author>Christoph Palm</author>
    <author>Helmut Messmann</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Lernen</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Neuronales Netz</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Speiseröhrenkrebs</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Artificial Intelligence</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Machine learning</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Adenocarcinoma</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Barrett’s cancer</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>submucosal invasion</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="ddc" number="6">Technik, Medizin, angewandte Wissenschaften</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCHST">Regensburg Center of Health Sciences and Technology - RCHST</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>662</id>
    <completedYear/>
    <publishedYear>2020</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>12</pageNumber>
    <edition/>
    <issue>November</issue>
    <volume>126</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2020-10-23</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Assisting Barrett's esophagus identification using endoscopic data augmentation based on Generative Adversarial Networks</title>
    <abstract language="eng">Barrett's esophagus figured a swift rise in the number of cases in the past years. Although traditional diagnosis methods offered a vital role in early-stage treatment, they are generally time- and resource-consuming. In this context, computer-aided approaches for automatic diagnosis emerged in the literature since early detection is intrinsically related to remission probabilities. However, they still suffer from drawbacks because of the lack of available data for machine learning purposes, thus implying reduced recognition rates. This work introduces Generative Adversarial Networks to generate high-quality endoscopic images, thereby identifying Barrett's esophagus and adenocarcinoma more precisely. Further, Convolution Neural Networks are used for feature extraction and classification purposes. The proposed approach is validated over two datasets of endoscopic images, with the experiments conducted over the full and patch-split images. The application of Deep Convolutional Generative Adversarial Networks for the data augmentation step and LeNet-5 and AlexNet for the classification step allowed us to validate the proposed methodology over an extensive set of datasets (based on original and augmented sets), reaching results of 90% of accuracy for the patch-based approach and 85% for the image-based approach. Both results are based on augmented datasets and are statistically different from the ones obtained in the original datasets of the same kind. Moreover, the impact of data augmentation was evaluated in the context of image description and classification, and the results obtained using synthetic images outperformed the ones over the original datasets, as well as other recent approaches from the literature. Such results suggest promising insights related to the importance of proper data for the accurate classification concerning computer-assisted Barrett's esophagus and adenocarcinoma detection.</abstract>
    <parentTitle language="eng">Computers in Biology and Medicine</parentTitle>
    <identifier type="doi">10.1016/j.compbiomed.2020.104029</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <author>Luis Antonio de Souza Jr.</author>
    <author>Leandro A. Passos</author>
    <author>Robert Mendel</author>
    <author>Alanna Ebigbo</author>
    <author>Andreas Probst</author>
    <author>Helmut Messmann</author>
    <author>Christoph Palm</author>
    <author>João Paulo Papa</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Lernen</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Barrett's esophagus</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Machine learning</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Adenocarcinoma</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Generative adversarial networks</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Neuronales Netz</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Adenocarcinom</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Speiseröhrenkrebs</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="ddc" number="6">Technik, Medizin, angewandte Wissenschaften</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCHST">Regensburg Center of Health Sciences and Technology - RCHST</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
    <collection role="oaweg" number="">Hybrid Open Access - OA-Veröffentlichung in einer Subskriptionszeitschrift/-medium</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>98</id>
    <completedYear/>
    <publishedYear>2019</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>475</pageFirst>
    <pageLast>485</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>59</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2019-12-18</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Barrett's esophagus analysis using infinity Restricted Boltzmann Machines</title>
    <abstract language="eng">The number of patients with Barret’s esophagus (BE) has increased in the last decades. Considering the dangerousness of the disease and its evolution to adenocarcinoma, an early diagnosis of BE may provide a high probability of cancer remission. However, limitations regarding traditional methods of detection and management of BE demand alternative solutions. As such, computer-aided tools have been recently used to assist in this problem, but the challenge still persists. To manage the problem, we introduce the infinity Restricted Boltzmann Machines (iRBMs) to the task of automatic identification of Barrett’s esophagus from endoscopic images of the lower esophagus. Moreover, since iRBM requires a proper selection of its meta-parameters, we also present a discriminative iRBM fine-tuning using six meta-heuristic optimization techniques. We showed that iRBMs are suitable for the context since it provides competitive results, as well as the meta-heuristic techniques showed to be appropriate for such task.</abstract>
    <parentTitle language="eng">Journal of Visual Communication and Image Representation</parentTitle>
    <identifier type="doi">10.1016/j.jvcir.2019.01.043</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Leandro A. Passos</author>
    <author>Luis Antonio de Souza Jr.</author>
    <author>Robert Mendel</author>
    <author>Alanna Ebigbo</author>
    <author>Andreas Probst</author>
    <author>Helmut Messmann</author>
    <author>Christoph Palm</author>
    <author>João Paulo Papa</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Speiseröhrenkrankheit</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Boltzmann-Maschine</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Barrett’s esophagus</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Infinity Restricted Boltzmann Machines</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Meta-heuristics</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Deep learning</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Metaheuristik</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Lernen</value>
    </subject>
    <collection role="ddc" number="000">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="ddc" number="610">Medizin und Gesundheit</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCHST">Regensburg Center of Health Sciences and Technology - RCHST</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>110</id>
    <completedYear/>
    <publishedYear>2017</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>308</pageFirst>
    <pageLast>314</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Barrett's Esophagus Identification Using Optimum-Path Forest</title>
    <abstract language="eng">Computer-assisted analysis of endoscopic images can be helpful to the automatic diagnosis and classification of neoplastic lesions. Barrett's esophagus (BE) is a common type of reflux that is not straight forward to be detected by endoscopic surveillance, thus being way susceptible to erroneous diagnosis, which can cause cancer when not treated properly. In this work, we introduce the Optimum-Path Forest (OPF) classifier to the task of automatic identification of Barrett'sesophagus, with promising results and outperforming the well known Support Vector Machines (SVM) in the aforementioned context. We consider describing endoscopic images by means of feature extractors based on key point information, such as the Speeded up Robust Features (SURF) and Scale-Invariant Feature Transform (SIFT), for further designing a bag-of-visual-wordsthat is used to feed both OPF and SVM classifiers. The best results were obtained by means of the OPF classifier for both feature extractors, with values lying on 0.732 (SURF) - 0.735(SIFT) for sensitivity, 0.782 (SURF) - 0.806 (SIFT) for specificity, and 0.738 (SURF) - 0.732 (SIFT) for the accuracy.</abstract>
    <parentTitle language="eng">Proceedings of the 30th Conference on Graphics, Patterns and Images Tutorials (SIBGRAPI-T 2017), Niterói, Rio de Janeiro, Brazil, 2017,  17-20 October</parentTitle>
    <identifier type="doi">10.1109/SIBGRAPI.2017.47</identifier>
    <author>Luis Antonio de Souza Jr.</author>
    <author>Luis Claudio Sugi Afonso</author>
    <author>Christoph Palm</author>
    <author>João Paulo Papa</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Speiseröhrenkrankheit</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Lernen</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Bilderkennung</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Automatische Klassifikation</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCBE">Regensburg Center of Biomedical Engineering - RCBE</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>6</id>
    <completedYear/>
    <publishedYear>2019</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1143</pageFirst>
    <pageLast>1145</pageLast>
    <pageNumber>3</pageNumber>
    <edition/>
    <issue>7</issue>
    <volume>68</volume>
    <type>article</type>
    <publisherName>British Society of Gastroenterology</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2018-12-03</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Computer-aided diagnosis using deep learning in the evaluation of early oesophageal adenocarcinoma</title>
    <abstract language="eng">Computer-aided diagnosis using deep learning (CAD-DL) may be an instrument to improve endoscopic assessment of Barrett’s oesophagus&#13;
(BE) and early oesophageal adenocarcinoma (EAC). Based on still images from two databases, the diagnosis of EAC by CAD-DL reached sensitivities/specificities of 97%/88% (Augsburg data) and 92%/100% (Medical Image Computing and Computer-Assisted Intervention [MICCAI]&#13;
data) for white light (WL) images and 94%/80% for narrow band images (NBI) (Augsburg data), respectively. Tumour margins delineated by&#13;
experts into images were detected satisfactorily with a Dice coefficient (D) of 0.72. This could be a first step towards CAD-DL for BE assessment. If developed further, it could become a useful&#13;
adjunctive tool for patient management.</abstract>
    <parentTitle language="eng">GuT</parentTitle>
    <identifier type="doi">10.1136/gutjnl-2018-317573</identifier>
    <identifier type="urn">urn:nbn:de:bvb:898-opus4-68</identifier>
    <note>Corresponding authors: Alanna Ebigbo and Christoph Palm</note>
    <enrichment key="opus.import.file">1</enrichment>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Creative Commons - CC BY-NC - Namensnennung - Nicht kommerziell 4.0 International</licence>
    <author>Alanna Ebigbo</author>
    <author>Robert Mendel</author>
    <author>Andreas Probst</author>
    <author>Johannes Manzeneder</author>
    <author>Luis Antonio de Souza Jr.</author>
    <author>João Paulo Papa</author>
    <author>Christoph Palm</author>
    <author>Helmut Messmann</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Speiseröhrenkrebs</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Computerunterstütztes Verfahren</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Lernen</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCHST">Regensburg Center of Health Sciences and Technology - RCHST</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="oaweg" number="">Hybrid Open Access - OA-Veröffentlichung in einer Subskriptionszeitschrift/-medium</collection>
    <collection role="oaweg" number="">Corresponding author der OTH Regensburg</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
    <thesisPublisher>Ostbayerische Technische Hochschule Regensburg</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-oth-regensburg/files/6/gutjnl_2018_ebigbo.pdf</file>
  </doc>
  <doc>
    <id>108</id>
    <completedYear/>
    <publishedYear>2017</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>141</pageFirst>
    <pageLast>146</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>Springer</publisherName>
    <publisherPlace>Berlin</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Barrett's Esophagus Analysis Using SURF Features</title>
    <abstract language="eng">The development of adenocarcinoma in Barrett’s esophagus is difficult to detect by endoscopic surveillance of patients with signs of dysplasia. Computer assisted diagnosis of endoscopic images (CAD) could therefore be most helpful in the demarcation and classification of neoplastic lesions. In this study we tested the feasibility of a CAD method based on Speeded up Robust Feature Detection (SURF). A given database containing 100 images from 39 patients served as benchmark for feature based classification models. Half of the images had previously been diagnosed by five clinical experts as being ”cancerous”, the other half as ”non-cancerous”. Cancerous image regions had been visibly delineated (masked) by the clinicians. SURF features acquired from full images as well as from masked areas were utilized for the supervised training and testing of an SVM classifier. The predictive accuracy of the developed CAD system is illustrated by sensitivity and specificity values. The results based on full image matching where 0.78 (sensitivity) and 0.82 (specificity) were achieved, while the masked region approach generated results of 0.90 and 0.95, respectively.</abstract>
    <parentTitle language="deu">Bildverarbeitung für die Medizin 2017; Algorithmen - Systeme - Anwendungen. Proceedings des Workshops vom 12. bis 14. März 2017 in Heidelberg</parentTitle>
    <identifier type="doi">10.1007/978-3-662-54345-0_34</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <author>Luis Antonio de Souza Jr.</author>
    <author>Christian Hook</author>
    <author>João Paulo Papa</author>
    <author>Christoph Palm</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Speiseröhrenkrankheit</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Sehen</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Automatische Klassifikation</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCBE">Regensburg Center of Biomedical Engineering - RCBE</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>7119</id>
    <completedYear/>
    <publishedYear>2024</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>10445</pageFirst>
    <pageLast>10459</pageLast>
    <pageNumber>15</pageNumber>
    <edition/>
    <issue/>
    <volume>36</volume>
    <type>article</type>
    <publisherName>Springer</publisherName>
    <publisherPlace>London</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2024-03-14</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">DeepCraftFuse: visual and deeply-learnable features work better together for esophageal cancer detection in patients with Barrett’s esophagus</title>
    <abstract language="eng">Limitations in computer-assisted diagnosis include lack of labeled data and inability to model the relation between what experts see and what computers learn. Even though artificial intelligence and machine learning have demonstrated remarkable performances in medical image computing, their accountability and transparency level must be improved to transfer this success into clinical practice. The reliability of machine learning decisions must be explained and interpreted, especially for supporting the medical diagnosis. While deep learning techniques are broad so that unseen information might help learn patterns of interest, human insights to describe objects of interest help in decision-making. This paper proposes a novel approach, DeepCraftFuse, to address the challenge of combining information provided by deep networks with visual-based features to significantly enhance the correct identification of cancerous tissues in patients affected with Barrett’s esophagus (BE). We demonstrate that DeepCraftFuse outperforms state-of-the-art techniques on private and public datasets, reaching results of around 95% when distinguishing patients affected by BE that is either positive or negative to esophageal cancer.</abstract>
    <parentTitle language="eng">Neural Computing and Applications</parentTitle>
    <identifier type="doi">10.1007/s00521-024-09615-z</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <enrichment key="Kostentraeger">2027700</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Luis Antonio de Souza Jr.</author>
    <author>André G.C. Pacheco</author>
    <author>Leandro A. Passos</author>
    <author>Marcos Cleison S. Santana</author>
    <author>Robert Mendel</author>
    <author>Alanna Ebigbo</author>
    <author>Andreas Probst</author>
    <author>Helmut Messmann</author>
    <author>Christoph Palm</author>
    <author>João Paulo Papa</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Deep Learning</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Speiseröhrenkrebs</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Adenocarcinom</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Endobrachyösophagus</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Lernen</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Machine learning</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Adenocarcinoma</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Object detector</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Barrett’s esophagus</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Deep Learning</value>
    </subject>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
</export-example>
