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    <language>eng</language>
    <pageFirst>79</pageFirst>
    <pageLast>88</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>136</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
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    <title language="eng">A new computer vision-based approach to aid the diagnosis of Parkinson's disease</title>
    <abstract language="eng">Background and Objective: Even today, pointing out an exam that can diagnose a patient with Parkinson's disease (PD) accurately enough is not an easy task. Although a number of techniques have been used in search for a more precise method, detecting such illness and measuring its level of severity early enough to postpone its side effects are not straightforward. In this work, after reviewing a considerable number of works, we conclude that only a few techniques address the problem of PD recognition by means of micrography using computer vision techniques. Therefore, we consider the problem of aiding automatic PD diagnosis by means of spirals and meanders filled out in forms, which are then compared with the template for feature extraction.&#13;
Methods: In our work, both the template and the drawings are identified and separated automatically using image processing techniques, thus needing no user intervention. Since we have no registered images, the idea is to obtain a suitable representation of both template and drawings using the very same approach for all images in a fast and accurate approach.&#13;
Results: The results have shown that we can obtain very reasonable recognition rates (around approximate to 67%), with the most accurate class being the one represented by the patients, which outnumbered the control individuals in the proposed dataset.&#13;
Conclusions: The proposed approach seemed to be suitable for aiding in automatic PD diagnosis by means of computer vision and machine learning techniques. Also, meander images play an important role, leading to higher accuracies than spiral images. We also observed that the main problem in detecting PD is the patients in the early stages, who can draw near-perfect objects, which are very similar to the ones made by control patients. (C) 2016 Elsevier Ireland Ltd. All rights reserved.</abstract>
    <parentTitle language="eng">Computer Methods and Programs in Biomedicine</parentTitle>
    <identifier type="doi">10.1016/j.cmpb.2016.08.005</identifier>
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    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Clayton R. Pereira</author>
    <author>Danilo R. Pereira</author>
    <author>Francisco A. Silva</author>
    <author>Joao P. Masieiro</author>
    <author>Silke A. T. Weber</author>
    <author>Christian Hook</author>
    <author>João Paulo Papa</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>CLASSIFICATION</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Micrography</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Parkinson's disease</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Pattern recognition</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>SPEECH</value>
    </subject>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
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  <doc>
    <id>8471</id>
    <completedYear/>
    <publishedYear>2025</publishedYear>
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    <language>eng</language>
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    <pageNumber>36</pageNumber>
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    <title language="eng">Comparative validation of surgical phase recognition, instrument keypoint estimation, and instrument instance segmentation in endoscopy: Results of the PhaKIR 2024 challenge</title>
    <abstract language="eng">Reliable recognition and localization of surgical instruments in endoscopic video recordings are foundational for a wide range of applications in computer- and robot-assisted minimally invasive surgery (RAMIS), including surgical training, skill assessment, and autonomous assistance. However, robust performance under real-world conditions remains a significant challenge. Incorporating surgical context - such as the current procedural phase - has emerged as a promising strategy to improve robustness and interpretability. To address these challenges, we organized the Surgical Procedure Phase, Keypoint, and Instrument Recognition (PhaKIR) sub-challenge as part of the Endoscopic Vision (EndoVis) challenge at MICCAI 2024. We introduced a novel, multi-center dataset comprising thirteen full-length laparoscopic cholecystectomy videos collected from three distinct medical institutions, with unified annotations for three interrelated tasks: surgical phase recognition, instrument keypoint estimation, and instrument instance segmentation. Unlike existing datasets, ours enables joint investigation of instrument localization and procedural context within the same data while supporting the integration of temporal information across entire procedures. We report results and findings in accordance with the BIAS guidelines for biomedical image analysis challenges. The PhaKIR sub-challenge advances the field by providing a unique benchmark for developing temporally aware, context-driven methods in RAMIS and offers a high-quality resource to support future research in surgical scene understanding.</abstract>
    <identifier type="arxiv">2507.16559</identifier>
    <note>Der Aufsatz wurde peer-reviewed veröffentlicht und ist ebenfalls in diesem Repositorium verzeichnet unter: https://opus4.kobv.de/opus4-oth-regensburg/frontdoor/index/index/start/0/rows/10/sortfield/score/sortorder/desc/searchtype/simple/query/10.1016%2Fj.media.2026.103945/docId/8846</note>
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    <licence>Creative Commons - CC BY-NC-SA - Namensnennung - Nicht kommerziell -  Weitergabe unter gleichen Bedingungen 4.0 International</licence>
    <author>Tobias Rückert</author>
    <author>David Rauber</author>
    <author>Raphaela Maerkl</author>
    <author>Leonard Klausmann</author>
    <author>Suemeyye R. Yildiran</author>
    <author>Max Gutbrod</author>
    <author>Danilo Weber Nunes</author>
    <author>Alvaro Fernandez Moreno</author>
    <author>Imanol Luengo</author>
    <author>Danail Stoyanov</author>
    <author>Nicolas Toussaint</author>
    <author>Enki Cho</author>
    <author>Hyeon Bae Kim</author>
    <author>Oh Sung Choo</author>
    <author>Ka Young Kim</author>
    <author>Seong Tae Kim</author>
    <author>Gonçalo Arantes</author>
    <author>Kehan Song</author>
    <author>Jianjun Zhu</author>
    <author>Junchen Xiong</author>
    <author>Tingyi Lin</author>
    <author>Shunsuke Kikuchi</author>
    <author>Hiroki Matsuzaki</author>
    <author>Atsushi Kouno</author>
    <author>João Renato Ribeiro Manesco</author>
    <author>João Paulo Papa</author>
    <author>Tae-Min Choi</author>
    <author>Tae Kyeong Jeong</author>
    <author>Juyoun Park</author>
    <author>Oluwatosin Alabi</author>
    <author>Meng Wei</author>
    <author>Tom Vercauteren</author>
    <author>Runzhi Wu</author>
    <author>Mengya Xu</author>
    <author> an Wang</author>
    <author>Long Bai</author>
    <author>Hongliang Ren</author>
    <author>Amine Yamlahi</author>
    <author>Jakob Hennighausen</author>
    <author>Lena Maier-Hein</author>
    <author>Satoshi Kondo</author>
    <author>Satoshi Kasai</author>
    <author>Kousuke Hirasawa</author>
    <author>Shu Yang</author>
    <author>Yihui Wang</author>
    <author>Hao Chen</author>
    <author>Santiago Rodríguez</author>
    <author>Nicolás Aparicio</author>
    <author>Leonardo Manrique</author>
    <author>Juan Camilo Lyons</author>
    <author>Olivia Hosie</author>
    <author>Nicolás Ayobi</author>
    <author>Pablo Arbeláez</author>
    <author>Yiping Li</author>
    <author>Yasmina Al Khalil</author>
    <author>Sahar Nasirihaghighi</author>
    <author>Stefanie Speidel</author>
    <author>Daniel Rückert</author>
    <author>Hubertus Feussner</author>
    <author>Dirk Wilhelm</author>
    <author>Christoph Palm</author>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCBE">Regensburg Center of Biomedical Engineering - RCBE</collection>
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    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
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  <doc>
    <id>8846</id>
    <completedYear/>
    <publishedYear>2026</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>31</pageNumber>
    <edition/>
    <issue/>
    <volume>109</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
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    <title language="eng">Comparative validation of surgical phase recognition, instrument keypoint estimation, and instrument instance segmentation in endoscopy: Results of the PhaKIR 2024 challenge</title>
    <abstract language="eng">Reliable recognition and localization of surgical instruments in endoscopic video recordings are foundational for a wide range of applications in computer- and robot-assisted minimally invasive surgery (RAMIS), including surgical training, skill assessment, and autonomous assistance. However, robust performance under real-world conditions remains a significant challenge. Incorporating surgical context – such as the current procedural phase – has emerged as a promising strategy to improve robustness and interpretability.&#13;
To address these challenges, we organized the Surgical Procedure Phase, Keypoint, and Instrument Recognition (PhaKIR) sub-challenge as part of the Endoscopic Vision (EndoVis) challenge at MICCAI 2024. We introduced a novel, multi-center dataset comprising thirteen full-length laparoscopic cholecystectomy videos collected from three distinct medical institutions, with unified annotations for three interrelated tasks: surgical phase recognition, instrument keypoint estimation, and instrument instance segmentation. Unlike existing datasets, ours enables joint investigation of instrument localization and procedural context within the same data while supporting the integration of temporal information across entire procedures.&#13;
We report results and findings in accordance with the BIAS guidelines for biomedical image analysis challenges. The PhaKIR sub-challenge advances the field by providing a unique benchmark for developing temporally aware, context-driven methods in RAMIS and offers a high-quality resource to support future research in surgical scene understanding.</abstract>
    <parentTitle language="eng">Medical Image Analysis</parentTitle>
    <identifier type="issn">1361-8415</identifier>
    <identifier type="doi">10.1016/j.media.2026.103945</identifier>
    <note>Corresponding author der OTH Regensburg: Tobias Rueckert&#13;
&#13;
Die Preprint-Version ist ebenfalls in diesem Repositorium verzeichnet unter: &#13;
https://opus4.kobv.de/opus4-oth-regensburg/solrsearch/index/search/start/0/rows/10/sortfield/score/sortorder/desc/searchtype/simple/query/2507.16559</note>
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    <enrichment key="CorrespondingAuthor">Tobias Rueckert</enrichment>
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    <licence>Creative Commons - CC BY-NC - Namensnennung - Nicht kommerziell 4.0 International</licence>
    <author>Tobias Rueckert</author>
    <author>David Rauber</author>
    <author>Raphaela Maerkl</author>
    <author>Leonard Klausmann</author>
    <author>Suemeyye R. Yildiran</author>
    <author>Max Gutbrod</author>
    <author>Danilo Weber Nunes</author>
    <author>Alvaro Fernandez Moreno</author>
    <author>Imanol Luengo</author>
    <author>Danail Stoyanov</author>
    <author>Nicolas Toussaint</author>
    <author>Enki Cho</author>
    <author>Hyeon Bae Kim</author>
    <author>Oh Sung Choo</author>
    <author>Ka Young Kim</author>
    <author>Seong Tae Kim</author>
    <author>Gonçalo Arantes</author>
    <author>Kehan Song</author>
    <author>Jianjun Zhu</author>
    <author>Junchen Xiong</author>
    <author>Tingyi Lin</author>
    <author>Shunsuke Kikuchi</author>
    <author>Hiroki Matsuzaki</author>
    <author>Atsushi Kouno</author>
    <author>João Renato Ribeiro Manesco</author>
    <author>João Paulo Papa</author>
    <author>Tae-Min Choi</author>
    <author>Tae Kyeong Jeong</author>
    <author>Juyoun Park</author>
    <author>Oluwatosin Alabi</author>
    <author>Meng Wei</author>
    <author>Tom Vercauteren</author>
    <author>Runzhi Wu</author>
    <author>Mengya Xu</author>
    <author>An Wang</author>
    <author>Long Bai</author>
    <author>Hongliang Ren</author>
    <author>Amine Yamlahi</author>
    <author>Jakob Hennighausen</author>
    <author>Lena Maier-Hein</author>
    <author>Satoshi Kondo</author>
    <author>Satoshi Kasai</author>
    <author>Kousuke Hirasawa</author>
    <author>Shu Yang</author>
    <author>Yihui Wang</author>
    <author>Hao Chen</author>
    <author>Santiago Rodríguez</author>
    <author>Nicolás Aparicio</author>
    <author>Leonardo Manrique</author>
    <author>Christoph Palm</author>
    <author>Dirk Wilhelm</author>
    <author>Hubertus Feussner</author>
    <author>Daniel Rueckert</author>
    <author>Stefanie Speidel</author>
    <author>Sahar Nasirihaghighi</author>
    <author>Yasmina Al Khalil</author>
    <author>Yiping Li</author>
    <author>Pablo Arbeláez</author>
    <author>Nicolás Ayobi</author>
    <author>Olivia Hosie</author>
    <author>Juan Camilo Lyons</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Surgical phase recognition</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Instrument keypoint estimation</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Instrument instance segmentation</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Robot-assisted surgery</value>
    </subject>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCBE">Regensburg Center of Biomedical Engineering - RCBE</collection>
    <collection role="institutes" number="RCHST">Regensburg Center of Health Sciences and Technology - RCHST</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="oaweg" number="">Hybrid Open Access - OA-Veröffentlichung in einer Subskriptionszeitschrift/-medium</collection>
    <collection role="oaweg" number="">Corresponding author der OTH Regensburg</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
    <collection role="funding" number="">DEAL Elsevier</collection>
    <collection role="DFGFachsystematik" number="1">Ingenieurwissenschaften</collection>
    <collection role="othforschungsschwerpunkt" number="">Digitale Transformation</collection>
  </doc>
  <doc>
    <id>4662</id>
    <completedYear/>
    <publishedYear>2017</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>70</pageFirst>
    <pageLast>80</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>10425</volume>
    <type>bookpart</type>
    <publisherName>Springer</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
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    <title language="eng">Parkinson’s Disease Identification Using Restricted Boltzmann Machines</title>
    <abstract language="eng">Currently, Parkinson’s Disease (PD) has no cure or accurate diagnosis, reaching approximately 60, 000 new cases yearly and worldwide, being more often in the elderly population. Its main symptoms can not be easily uncorrelated with other illness, being way more difficult to be identified at the early stages. As such, computer-aided tools have been recently used to assist in this task, but the challenge in the automatic identification of Parkinson’s Disease still persists. In order to cope with this problem, we propose to employ Restricted Boltzmann Machines (RBMs) to learn features in an unsupervised fashion by analyzing images from handwriting exams, which aim at assessing the writing skills of potential individuals. These are one of the main symptoms of PD-prone people, since such kind of ability ends up being severely affected. We show that RBMs can learn proper features that help supervised classifiers in the task of automatic identification of PD patients, as well as one can obtain a more compact representation of the exam for the sake of storage and computational load purposes.</abstract>
    <parentTitle language="eng">Computer Analysis of Images and Patterns, 17th International Conference, CAIP 2017, Ystad, Sweden, August 22-24, 2017, Proceedings, Part II</parentTitle>
    <identifier type="isbn">978-3-319-64697-8</identifier>
    <identifier type="doi">10.1007/978-3-319-64698-5_7</identifier>
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    <enrichment key="OtherSeries">Lecture Notes in Computer Science ; 10425</enrichment>
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    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Clayton R. Pereira</author>
    <author>Leandro A. Passos</author>
    <author>Ricardo R. Lopes</author>
    <author>Silke A. T. Weber</author>
    <author>Christian Hook</author>
    <author>Joao Paulo Papa</author>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Bevölkerung</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>Handschrift</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>uncontrolled</type>
      <value>maschinelles Lernen</value>
    </subject>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
  </doc>
  <doc>
    <id>3153</id>
    <completedYear/>
    <publishedYear>2018</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>67</pageFirst>
    <pageLast>77</pageLast>
    <pageNumber/>
    <edition/>
    <issue>May</issue>
    <volume>37</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
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    <title language="eng">Handwritten dynamics assessment through convolutional neural networks</title>
    <abstract language="eng">Background and objective&#13;
Parkinson’s disease (PD) is considered a degenerative disorder that affects the motor system, which may cause tremors, micrography, and the freezing of gait. Although PD is related to the lack of dopamine, the triggering process of its development is not fully understood yet.&#13;
Methods&#13;
In this work, we introduce convolutional neural networks to learn features from images produced by handwritten dynamics, which capture different information during the individual’s assessment. Additionally, we make available a dataset composed of images and signal-based data to foster the research related to computer-aided PD diagnosis.&#13;
Results&#13;
The proposed approach was compared against raw data and texture-based descriptors, showing suitable results, mainly in the context of early stage detection, with results nearly to 95%.&#13;
Conclusions&#13;
The analysis of handwritten dynamics using deep learning techniques showed to be useful for automatic Parkinson’s disease identification, as well as it can outperform handcrafted features.</abstract>
    <parentTitle language="eng">Artificial Intelligence in Medicine</parentTitle>
    <subTitle language="deu">An application to Parkinson’s disease identification</subTitle>
    <identifier type="doi">10.1016/j.artmed.2018.04.001</identifier>
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    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Clayton R. Pereira</author>
    <author>Danilo R. Pereira</author>
    <author>Gustavo H. Rosa</author>
    <author>Victor Hugo C. Albuquerque</author>
    <author>Silke A. T. Weber</author>
    <author>Christian Hook</author>
    <author>João Paulo Papa</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Convolutional neural networks</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Handwritten dynamics</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Parkinson’s disease</value>
    </subject>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
  </doc>
  <doc>
    <id>2531</id>
    <completedYear/>
    <publishedYear>2019</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>282</pageFirst>
    <pageLast>292</pageLast>
    <pageNumber/>
    <edition/>
    <issue>May</issue>
    <volume>94</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
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    <title language="eng">A recurrence plot-based approach for Parkinson's disease identification</title>
    <abstract language="eng">Parkinson's disease (PD) is a neurodegenerative disease that affects millions of people worldwide, causing mental and mainly motor dysfunctions. The negative impact on the patient's daily routine has moved the science in search of new techniques that can reduce its negative effects and also identify the disease in individuals. One of the main motor characteristics of PD is the hand tremor faced by patients, which turns out to be a crucial information to be used towards a computer-aided diagnosis. In this context, we make use of handwriting dynamics data acquired from individuals when submitted to some tasks that measure abilities related to writing skills. This work proposes the application of recurrence plots to map the signals onto the image domain, which are further used to feed a Convolutional Neural Network for learning proper information that can help the automatic identification of PD. The proposed approach was assessed in a public dataset under several scenarios that comprise different combinations of deep-based architectures, image resolutions, and training set sizes. Experimental results showed significant accuracy improvement compared to our previous work with an average accuracy of over 87%. Moreover, it was observed an improvement in accuracy concerning the classification of patients (i.e., mean recognition rates above to 90%). The promising results showed the potential of the proposed approach towards the automatic identification of Parkinson's disease.</abstract>
    <parentTitle language="eng">Future generation computer systems - The international journal of escience</parentTitle>
    <identifier type="doi">10.1016/j.future.2018.11.054</identifier>
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    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Luis Claudio Sugi Afonso</author>
    <author>Gustavo H. Rosa</author>
    <author>Clayton R. Pereira</author>
    <author>Silke A. T. Weber</author>
    <author>Christian Hook</author>
    <author>Victor Hugo C. Albuquerque</author>
    <author>Joao Paulo Papa</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Classification</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Convolutional neural networks</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>diagnosis</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Optimum-path forest</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Parkinson's disease</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Recurrence plot</value>
    </subject>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
  </doc>
  <doc>
    <id>2582</id>
    <completedYear/>
    <publishedYear>2020</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue>August</issue>
    <volume>71</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Hierarchical learning using deep optimum-path forest</title>
    <abstract language="eng">Bag-of-Visual Words (BoVW) and deep learning techniques have been widely used in several domains, which include computer-assisted medical diagnoses. In this work, we are interested in developing tools for the automatic identification of Parkinson’s disease using machine learning and the concept of BoVW. The proposed approach concerns a hierarchical-based learning technique to design visual dictionaries through the Deep Optimum-Path Forest classifier. The proposed method was evaluated in six datasets derived from data collected from individuals when performing handwriting exams. Experimental results showed the potential of the technique, with robust achievements.</abstract>
    <parentTitle language="eng">Journal of Visual Communication and Image Representation</parentTitle>
    <identifier type="doi">10.1016/j.jvcir.2020.102823</identifier>
    <enrichment key="opus.import.date">2022-01-27T15:33:58+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Luis Claudio Sugi Afonso</author>
    <author>Clayton R. Pereira</author>
    <author>Silke A. T. Weber</author>
    <author>Christian Hook</author>
    <author>Alexandre X. Falcão</author>
    <author>Joao Paulo Papa</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Handwriting dynamics</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Hierarchical representation</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Optimum-path forest</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Parkinson’s disease</value>
    </subject>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
  </doc>
  <doc>
    <id>4757</id>
    <completedYear/>
    <publishedYear>2015</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>171</pageFirst>
    <pageLast>176</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>IEEE</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">A Step Towards the Automated Diagnosis of Parkinson's Disease: Analyzing Handwriting Movements</title>
    <abstract language="eng">Parkinson’s disease (PD) has affected millions of people world-wide, being its major problem the loss of movements and, consequently, the ability of working and locomotion. Although we can find several works that attempt at dealing with this problem out there, most of them make use of datasets composed by a few subjects only. In this work, we present some results toward the automated diagnosis of PD by means of computer vision-based techniques in a dataset composed by dozens of patients, which is one of the main contributions of this work. The dataset is part of a joint research project that aims at extracting both visual and signal-based information from healthy and PD patients in order to go forward the early diagnosis of PD patients. The dataset is composed by handwriting clinical exams that are analyzed by means of image processing and machine learning techniques, being the preliminary results encouraging and promising. Additionally, a new quantitative feature to measure the amount of tremor of an individual’s handwritten trace called Mean Relative Tremor is also presented.</abstract>
    <parentTitle language="eng">2015 IEEE 28th International Symposium on Computer-Based Medical Systems, 22.-25.06.2015, Sao Carlos, Brazil</parentTitle>
    <identifier type="doi">10.1109/cbms.2015.34</identifier>
    <identifier type="issn">2372-9198</identifier>
    <identifier type="isbn">978-1-4673-6775-2</identifier>
    <enrichment key="opus.import.date">2022-07-06T16:27:45+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <enrichment key="opus.doi.autoCreate">false</enrichment>
    <enrichment key="opus.urn.autoCreate">false</enrichment>
    <author>Clayton R. Pereira</author>
    <author>Danilo R. Pereira</author>
    <author>Francisco A. da Silva</author>
    <author>Christian Hook</author>
    <author>Silke A. T. Weber</author>
    <author>Luis A. M. Pereira</author>
    <author>João Paulo Papa</author>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
  </doc>
  <doc>
    <id>5429</id>
    <completedYear/>
    <publishedYear>2022</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>2388</pageFirst>
    <pageLast>2390</pageLast>
    <pageNumber/>
    <edition/>
    <issue>12</issue>
    <volume>71</volume>
    <type>article</type>
    <publisherName>BMJ</publisherName>
    <publisherPlace>London</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2022-09-16</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Vessel and tissue recognition during third-space endoscopy using a deep learning algorithm</title>
    <abstract language="eng">In this study, we aimed to develop an artificial intelligence clinical decision support solution to mitigate operator-dependent limitations during complex endoscopic procedures such as endoscopic submucosal dissection and peroral endoscopic myotomy, for example, bleeding and perforation. A DeepLabv3-based model was trained to delineate vessels, tissue structures and instruments on endoscopic still images from such procedures. The mean cross-validated Intersection over Union and Dice Score were 63% and 76%, respectively. Applied to standardised video clips from third-space endoscopic procedures, the algorithm showed a mean vessel detection rate of 85% with a false-positive rate of 0.75/min. These performance statistics suggest a potential clinical benefit for procedure safety, time and also training.</abstract>
    <parentTitle language="eng">Gut</parentTitle>
    <identifier type="doi">10.1136/gutjnl-2021-326470</identifier>
    <identifier type="urn">urn:nbn:de:bvb:898-opus4-54293</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <licence>Creative Commons - CC BY-NC - Namensnennung - Nicht kommerziell 4.0 International</licence>
    <author>Alanna Ebigbo</author>
    <author>Robert Mendel</author>
    <author>Markus W. Scheppach</author>
    <author>Andreas Probst</author>
    <author>Neal Shahidi</author>
    <author>Friederike Prinz</author>
    <author>Carola Fleischmann</author>
    <author>Christoph Römmele</author>
    <author>Stefan Karl Gölder</author>
    <author>Georg Braun</author>
    <author>David Rauber</author>
    <author>Tobias Rückert</author>
    <author>Luis Antonio de Souza Jr.</author>
    <author>João Paulo Papa</author>
    <author>Michael F. Byrne</author>
    <author>Christoph Palm</author>
    <author>Helmut Messmann</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Artificial Intelligence</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Endoscopy</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Medical Image Computing</value>
    </subject>
    <collection role="ddc" number="004">Datenverarbeitung; Informatik</collection>
    <collection role="ddc" number="617">Chirurgie und verwandte medizinische Fachrichtungen</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="oaweg" number="">Hybrid Open Access - OA-Veröffentlichung in einer Subskriptionszeitschrift/-medium</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
    <thesisPublisher>Ostbayerische Technische Hochschule Regensburg</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-oth-regensburg/files/5429/gutjnl-2021-326470.full_supp.pdf</file>
  </doc>
  <doc>
    <id>102</id>
    <completedYear/>
    <publishedYear>2018</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>203</pageFirst>
    <pageLast>213</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>96</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2019-12-18</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">A survey on Barrett's esophagus analysis using machine learning</title>
    <abstract language="eng">This work presents a systematic review concerning recent studies and technologies of machine learning for Barrett's esophagus (BE) diagnosis and treatment. The use of artificial intelligence is a brand new and promising way to evaluate such disease. We compile some works published at some well-established databases, such as Science Direct, IEEEXplore, PubMed, Plos One, Multidisciplinary Digital Publishing Institute (MDPI), Association for Computing Machinery (ACM), Springer, and Hindawi Publishing Corporation. Each selected work has been analyzed to present its objective, methodology, and results. The BE progression to dysplasia or adenocarcinoma shows a complex pattern to be detected during endoscopic surveillance. Therefore, it is valuable to assist its diagnosis and automatic identification using computer analysis. The evaluation of the BE dysplasia can be performed through manual or automated segmentation through machine learning techniques. Finally, in this survey, we reviewed recent studies focused on the automatic detection of the neoplastic region for classification purposes using machine learning methods.</abstract>
    <parentTitle language="eng">Computers in Biology and Medicine</parentTitle>
    <identifier type="doi">10.1016/j.compbiomed.2018.03.014</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Luis Antonio de Souza Jr.</author>
    <author>Christoph Palm</author>
    <author>Robert Mendel</author>
    <author>Christian Hook</author>
    <author>Alanna Ebigbo</author>
    <author>Andreas Probst</author>
    <author>Helmut Messmann</author>
    <author>Silke A. T. Weber</author>
    <author>João Paulo Papa</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Speiseröhrenkrankheit</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Mustererkennung</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Lernen</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Literaturbericht</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Barrett's esophagus</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Machine learning</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Adenocarcinoma</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Image processing</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Pattern recognition</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Computer-aided diagnosis</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCBE">Regensburg Center of Biomedical Engineering - RCBE</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>354</id>
    <completedYear/>
    <publishedYear>2019</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1616</pageFirst>
    <pageLast>1623</pageLast>
    <pageNumber/>
    <edition/>
    <issue>12</issue>
    <volume>07</volume>
    <type>article</type>
    <publisherName>Georg Thieme Verlag</publisherName>
    <publisherPlace>Stuttgart</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2020-04-22</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">A technical review of artificial intelligence as applied to gastrointestinal endoscopy: clarifying the terminology</title>
    <abstract language="eng">The growing number of publications on the application of artificial intelligence (AI) in medicine underlines the enormous importance and potential of this emerging field of research.&#13;
&#13;
In gastrointestinal endoscopy, AI has been applied to all segments of the gastrointestinal tract most importantly in the detection and characterization of colorectal polyps. However, AI research has been published also in the stomach and esophagus for both neoplastic and non-neoplastic disorders.&#13;
&#13;
The various technical as well as medical aspects of AI, however, remain confusing especially for non-expert physicians.&#13;
&#13;
This physician-engineer co-authored review explains the basic technical aspects of AI and provides a comprehensive overview of recent publications on AI in gastrointestinal endoscopy. Finally, a basic insight is offered into understanding publications on AI in gastrointestinal endoscopy.</abstract>
    <parentTitle language="eng">Endoscopy International Open</parentTitle>
    <identifier type="doi">10.1055/a-1010-5705</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Creative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International</licence>
    <author>Alanna Ebigbo</author>
    <author>Christoph Palm</author>
    <author>Andreas Probst</author>
    <author>Robert Mendel</author>
    <author>Johannes Manzeneder</author>
    <author>Friederike Prinz</author>
    <author>Luis Antonio de Souza Jr.</author>
    <author>João Paulo Papa</author>
    <author>Peter Siersema</author>
    <author>Helmut Messmann</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Lernen</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Gastroenterologie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Künstliche Intelligenz</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Barrett's esophagus</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Deep learning</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="ddc" number="6">Technik, Medizin, angewandte Wissenschaften</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCHST">Regensburg Center of Health Sciences and Technology - RCHST</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="oaweg" number="">Gold Open Access- Erstveröffentlichung in einem/als Open-Access-Medium</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>2012</id>
    <completedYear/>
    <publishedYear>2021</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1</pageFirst>
    <pageLast>14</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>135</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2021-06-25</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Convolutional Neural Networks for the evaluation of cancer in Barrett’s esophagus: Explainable AI to lighten up the black-box</title>
    <abstract language="eng">Even though artificial intelligence and machine learning have demonstrated remarkable performances in medical image computing, their level of accountability and transparency must be provided in such evaluations. The reliability related to machine learning predictions must be explained and interpreted, especially if diagnosis support is addressed. For this task, the black-box nature of deep learning techniques must be lightened up to transfer its promising results into clinical practice. Hence, we aim to investigate the use of explainable artificial intelligence techniques to quantitatively highlight discriminative regions during the classification of earlycancerous tissues in Barrett’s esophagus-diagnosed patients. Four Convolutional Neural Network models (AlexNet, SqueezeNet, ResNet50, and VGG16) were analyzed using five different interpretation techniques (saliency, guided backpropagation, integrated gradients, input × gradients, and DeepLIFT) to compare their agreement with experts’ previous annotations of cancerous tissue. We could show that saliency attributes match best with the manual experts’ delineations. Moreover, there is moderate to high correlation between the sensitivity of a model and the human-and-computer agreement. The results also lightened that the higher the model’s sensitivity, the stronger the correlation of human and computational segmentation agreement. We observed a relevant relation between computational learning and experts’ insights, demonstrating how human knowledge may influence the correct computational learning.</abstract>
    <parentTitle language="eng">Computers in Biology and Medicine</parentTitle>
    <identifier type="doi">10.1016/j.compbiomed.2021.104578</identifier>
    <identifier type="issn">0010-4825</identifier>
    <identifier type="urn">urn:nbn:de:bvb:898-opus4-20126</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Luis Antonio de Souza Jr.</author>
    <author>Robert Mendel</author>
    <author>Sophia Strasser</author>
    <author>Alanna Ebigbo</author>
    <author>Andreas Probst</author>
    <author>Helmut Messmann</author>
    <author>João Paulo Papa</author>
    <author>Christoph Palm</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Deep Learning</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Künstliche Intelligenz</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Computerunterstützte Medizin</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Barrett's esophagus</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Adenocarcinoma</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Machine learning</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Explainable artificial intelligence</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Computer-aided diagnosis</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="ddc" number="6">Technik, Medizin, angewandte Wissenschaften</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCHST">Regensburg Center of Health Sciences and Technology - RCHST</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="oaweg" number="">Gold Open Access- Erstveröffentlichung in einem/als Open-Access-Medium</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
    <thesisPublisher>Ostbayerische Technische Hochschule Regensburg</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-oth-regensburg/files/2012/1-s2.0-S0010482521003723-main.pdf</file>
  </doc>
  <doc>
    <id>352</id>
    <completedYear/>
    <publishedYear>2019</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>6</pageFirst>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue>04</issue>
    <volume>51</volume>
    <type>conferencepresentation</type>
    <publisherName>Georg Thieme Verlag</publisherName>
    <publisherPlace>Stuttgart</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2020-04-22</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Artificial Intelligence in Early Barrett's Cancer: The Segmentation Task</title>
    <abstract language="eng">Aims:&#13;
The delineation of outer margins of early Barrett's cancer can be challenging even for experienced endoscopists. Artificial intelligence (AI) could assist endoscopists faced with this task. As of date, there is very limited experience in this domain. In this study, we demonstrate the measure of overlap (Dice coefficient = D) between highly experienced Barrett endoscopists and an AI system in the delineation of cancer margins (segmentation task).&#13;
&#13;
Methods:&#13;
An AI system with a deep convolutional neural network (CNN) was trained and tested on high-definition endoscopic images of early Barrett's cancer (n = 33) and normal Barrett's mucosa (n = 41). The reference standard for the segmentation task were the manual delineations of tumor margins by three highly experienced Barrett endoscopists. Training of the AI system included patch generation, patch augmentation and adjustment of the CNN weights. Then, the segmentation results from patch classification and thresholding of the class probabilities. Segmentation results were evaluated using the Dice coefficient (D).&#13;
&#13;
Results:&#13;
The Dice coefficient (D) which can range between 0 (no overlap) and 1 (complete overlap) was computed only for images correctly classified by the AI-system as cancerous. At a threshold of t = 0.5, a mean value of D = 0.72 was computed.&#13;
&#13;
Conclusions:&#13;
AI with CNN performed reasonably well in the segmentation of the tumor region in Barrett's cancer, at least when compared with expert Barrett's endoscopists. AI holds a lot of promise as a tool for better visualization of tumor margins but may need further improvement and enhancement especially in real-time settings.</abstract>
    <parentTitle language="eng">Endoscopy</parentTitle>
    <identifier type="doi">10.1055/s-0039-1681187</identifier>
    <enrichment key="ConferenceStatement">ESGE Days 2019</enrichment>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Alanna Ebigbo</author>
    <author>Robert Mendel</author>
    <author>Andreas Probst</author>
    <author>Johannes Manzeneder</author>
    <author>Luis Antonio de Souza Jr.</author>
    <author>João Paulo Papa</author>
    <author>Christoph Palm</author>
    <author>Helmut Messmann</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Speiseröhrenkrankheit</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Lernen</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Barrett's esphagus</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Deep Learning</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Segmentation</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCBE">Regensburg Center of Biomedical Engineering - RCBE</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>356</id>
    <completedYear/>
    <publishedYear>2018</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>166</pageFirst>
    <pageLast>173</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Barrett's Esophagus Identification Using Color Co-occurrence Matrices</title>
    <abstract language="eng">In this work, we propose the use of single channel Color Co-occurrence Matrices for texture description of Barrett’sEsophagus (BE)and adenocarcinoma images. Further classification using supervised  learning techniques, such as Optimum-Path Forest (OPF), Support  Vector Machines with Radial Basisunction (SVM-RBF) and Bayesian classifier supports the contextof automatic BE and adenocarcinoma  diagnosis. We validated three approaches of classification based on  patches, patients and images in two datasets (MICCAI 2015 and  Augsburg) using the color-and-texture descriptors and the machine learning techniques. Concerning MICCAI 2015 dataset, the best results were obtained using the blue channel for the descriptors and the  supervised OPF for classification purposes in the patch-based   approach,  with sensitivity nearly to 73% for positive adenocarcinoma  identification and specificity close to 77% for BE (non-cancerous) patch classification. Regarding the Augsburg dataset, the most   accurate results were also obtained using both OPF classifier and  blue channel descriptor for the feature extraction, with sensitivity close to 67% and specificity around to76%. Our work highlights new advances in the related research area and provides a promising  technique that combines color and texture information, allied to  three different approaches of dataset pre-processing aiming to  configure robust scenarios for the classification step.</abstract>
    <parentTitle language="eng">31st SIBGRAPI Conference on Graphics, Patterns and Images (SIBGRAPI), Parana, 2018</parentTitle>
    <identifier type="doi">10.1109/SIBGRAPI.2018.00028</identifier>
    <author>Luis Antonio de Souza Jr.</author>
    <author>Alanna Ebigbo</author>
    <author>Andreas Probst</author>
    <author>Helmut Messmann</author>
    <author>João Paulo Papa</author>
    <author>Robert Mendel</author>
    <author>Christoph Palm</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Barrett’s  Esophagus</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Co-occurrence  Matrices</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Machine learning</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Texture Analysis</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>353</id>
    <completedYear/>
    <publishedYear>2020</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>615</pageFirst>
    <pageLast>616</pageLast>
    <pageNumber/>
    <edition/>
    <issue>4</issue>
    <volume>69</volume>
    <type>article</type>
    <publisherName>BMJ</publisherName>
    <publisherPlace>London</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2020-04-22</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Real-time use of artificial intelligence in the evaluation of cancer in Barrett’s oesophagus</title>
    <abstract language="eng">Based on previous work by our group with manual annotation of visible Barrett oesophagus (BE) cancer images, a real-time deep learning artificial intelligence (AI) system was developed. While an expert endoscopist conducts the endoscopic assessment of BE, our AI system captures random images from the real-time camera livestream and provides a global prediction (classification), as well as a dense prediction (segmentation) differentiating accurately between normal BE and early oesophageal adenocarcinoma (EAC). The AI system showed an accuracy of 89.9% on 14 cases with neoplastic BE.</abstract>
    <parentTitle language="eng">Gut</parentTitle>
    <identifier type="doi">10.1136/gutjnl-2019-319460</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Alanna Ebigbo</author>
    <author>Robert Mendel</author>
    <author>Andreas Probst</author>
    <author>Johannes Manzeneder</author>
    <author>Friederike Prinz</author>
    <author>Luis Antonio de Souza Jr.</author>
    <author>João Paulo Papa</author>
    <author>Christoph Palm</author>
    <author>Helmut Messmann</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Speiseröhrenkrankheit</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Lernen</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Barrett's esophagus</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Deep learning</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>real-time</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="ddc" number="6">Technik, Medizin, angewandte Wissenschaften</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCHST">Regensburg Center of Health Sciences and Technology - RCHST</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="oaweg" number="">Gold Open Access- Erstveröffentlichung in einem/als Open-Access-Medium</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>680</id>
    <completedYear/>
    <publishedYear>2021</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>878</pageFirst>
    <pageLast>883</pageLast>
    <pageNumber/>
    <edition/>
    <issue>09</issue>
    <volume>53</volume>
    <type>article</type>
    <publisherName>Thieme</publisherName>
    <publisherPlace>Stuttgart</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2020-11-28</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Endoscopic prediction of submucosal invasion in Barrett’s cancer with the use of Artificial Intelligence: A pilot Study</title>
    <abstract language="eng">Background and aims: The accurate differentiation between T1a and T1b Barrett’s cancer has both therapeutic and prognostic implications but is challenging even for experienced physicians. We trained an Artificial Intelligence (AI) system on the basis of deep artificial neural networks (deep learning) to differentiate between T1a and T1b Barrett’s cancer white-light images. &#13;
&#13;
Methods: Endoscopic images from three tertiary care centres in Germany were collected retrospectively. A deep learning system was trained and tested using the principles of cross-validation. A total of 230 white-light endoscopic images (108 T1a and 122 T1b) was evaluated with the AI-system. For comparison, the images were also classified by experts specialized in endoscopic diagnosis and treatment of Barrett’s cancer. &#13;
&#13;
Results: The sensitivity, specificity, F1 and accuracy of the AI-system in the differentiation between T1a and T1b cancer lesions was 0.77, 0.64, 0.73 and 0.71, respectively. There was no statistically significant difference between the performance of the AI-system and that of human experts with sensitivity, specificity, F1 and accuracy of 0.63, 0.78, 0.67 and 0.70 respectively. &#13;
&#13;
Conclusion: This pilot study demonstrates the first multicenter application of an AI-based system in the prediction of submucosal invasion in endoscopic images of Barrett’s cancer. AI scored equal to international experts in the field, but more work is necessary to improve the system and apply it to video sequences and in a real-life setting. Nevertheless, the correct prediction of submucosal invasion in Barret´s cancer remains challenging for both experts and AI.</abstract>
    <parentTitle language="eng">Endoscopy</parentTitle>
    <identifier type="doi">10.1055/a-1311-8570</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Alanna Ebigbo</author>
    <author>Robert Mendel</author>
    <author>Tobias Rückert</author>
    <author>Laurin Schuster</author>
    <author>Andreas Probst</author>
    <author>Johannes Manzeneder</author>
    <author>Friederike Prinz</author>
    <author>Matthias Mende</author>
    <author>Ingo Steinbrück</author>
    <author>Siegbert Faiss</author>
    <author>David Rauber</author>
    <author>Luis Antonio de Souza Jr.</author>
    <author>João Paulo Papa</author>
    <author>Pierre Deprez</author>
    <author>Tsuneo Oyama</author>
    <author>Akiko Takahashi</author>
    <author>Stefan Seewald</author>
    <author>Prateek Sharma</author>
    <author>Michael F. Byrne</author>
    <author>Christoph Palm</author>
    <author>Helmut Messmann</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Lernen</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Neuronales Netz</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Speiseröhrenkrebs</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Artificial Intelligence</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Machine learning</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Adenocarcinoma</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Barrett’s cancer</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>submucosal invasion</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="ddc" number="6">Technik, Medizin, angewandte Wissenschaften</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCHST">Regensburg Center of Health Sciences and Technology - RCHST</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>662</id>
    <completedYear/>
    <publishedYear>2020</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>12</pageNumber>
    <edition/>
    <issue>November</issue>
    <volume>126</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2020-10-23</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Assisting Barrett's esophagus identification using endoscopic data augmentation based on Generative Adversarial Networks</title>
    <abstract language="eng">Barrett's esophagus figured a swift rise in the number of cases in the past years. Although traditional diagnosis methods offered a vital role in early-stage treatment, they are generally time- and resource-consuming. In this context, computer-aided approaches for automatic diagnosis emerged in the literature since early detection is intrinsically related to remission probabilities. However, they still suffer from drawbacks because of the lack of available data for machine learning purposes, thus implying reduced recognition rates. This work introduces Generative Adversarial Networks to generate high-quality endoscopic images, thereby identifying Barrett's esophagus and adenocarcinoma more precisely. Further, Convolution Neural Networks are used for feature extraction and classification purposes. The proposed approach is validated over two datasets of endoscopic images, with the experiments conducted over the full and patch-split images. The application of Deep Convolutional Generative Adversarial Networks for the data augmentation step and LeNet-5 and AlexNet for the classification step allowed us to validate the proposed methodology over an extensive set of datasets (based on original and augmented sets), reaching results of 90% of accuracy for the patch-based approach and 85% for the image-based approach. Both results are based on augmented datasets and are statistically different from the ones obtained in the original datasets of the same kind. Moreover, the impact of data augmentation was evaluated in the context of image description and classification, and the results obtained using synthetic images outperformed the ones over the original datasets, as well as other recent approaches from the literature. Such results suggest promising insights related to the importance of proper data for the accurate classification concerning computer-assisted Barrett's esophagus and adenocarcinoma detection.</abstract>
    <parentTitle language="eng">Computers in Biology and Medicine</parentTitle>
    <identifier type="doi">10.1016/j.compbiomed.2020.104029</identifier>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <author>Luis Antonio de Souza Jr.</author>
    <author>Leandro A. Passos</author>
    <author>Robert Mendel</author>
    <author>Alanna Ebigbo</author>
    <author>Andreas Probst</author>
    <author>Helmut Messmann</author>
    <author>Christoph Palm</author>
    <author>João Paulo Papa</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Maschinelles Lernen</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Barrett's esophagus</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Machine learning</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Adenocarcinoma</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Generative adversarial networks</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Neuronales Netz</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Adenocarcinom</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Speiseröhrenkrebs</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Diagnose</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="ddc" number="6">Technik, Medizin, angewandte Wissenschaften</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCHST">Regensburg Center of Health Sciences and Technology - RCHST</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
    <collection role="oaweg" number="">Hybrid Open Access - OA-Veröffentlichung in einer Subskriptionszeitschrift/-medium</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
  </doc>
  <doc>
    <id>5779</id>
    <completedYear/>
    <publishedYear>2023</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>13</pageNumber>
    <edition/>
    <issue>March</issue>
    <volume>154</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2023-02-03</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Error-Correcting Mean-Teacher: Corrections instead of consistency-targets applied to semi-supervised medical image segmentation</title>
    <abstract language="eng">Semantic segmentation is an essential task in medical imaging research. Many powerful deep-learning-based approaches can be employed for this problem, but they are dependent on the availability of an expansive labeled dataset. In this work, we augment such supervised segmentation models to be suitable for learning from unlabeled data. Our semi-supervised approach, termed Error-Correcting Mean-Teacher, uses an exponential moving average model like the original Mean Teacher but introduces our new paradigm of error correction. The original segmentation network is augmented to handle this secondary correction task. Both tasks build upon the core feature extraction layers of the model. For the correction task, features detected in the input image are fused with features detected in the predicted segmentation and further processed with task-specific decoder layers. The combination of image and segmentation features allows the model to correct present mistakes in the given input pair. The correction task is trained jointly on the labeled data. On unlabeled data, the exponential moving average of the original network corrects the student’s prediction. The combined outputs of the students’ prediction with the teachers’ correction form the basis for the semi-supervised update. We evaluate our method with the 2017 and 2018 Robotic Scene Segmentation data, the ISIC 2017 and the BraTS 2020 Challenges, a proprietary Endoscopic Submucosal Dissection dataset, Cityscapes, and Pascal VOC 2012. Additionally, we analyze the impact of the individual components and examine the behavior when the amount of labeled data varies, with experiments performed on two distinct segmentation architectures. Our method shows improvements in terms of the mean Intersection over Union over the supervised baseline and competing methods. Code is available at https://github.com/CloneRob/ECMT.</abstract>
    <parentTitle language="eng">Computers in Biology and Medicine</parentTitle>
    <identifier type="doi">10.1016/j.compbiomed.2023.106585</identifier>
    <identifier type="issn">0010-4825</identifier>
    <identifier type="urn">urn:nbn:de:bvb:898-opus4-57790</identifier>
    <note>Corresponding author der OTH Regensburg: Robert Mendel</note>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="Kostentraeger">2027207</enrichment>
    <enrichment key="CorrespondingAuthor">Robert Mendel</enrichment>
    <licence>Creative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International</licence>
    <author>Robert Mendel</author>
    <author>David Rauber</author>
    <author>Luis Antonio de Souza Jr.</author>
    <author>João Paulo Papa</author>
    <author>Christoph Palm</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Semi-supervised Segmentation</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Mean-Teacher</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Pseudo-labels</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Medical Imaging</value>
    </subject>
    <collection role="ddc" number="00">Informatik, Wissen, Systeme</collection>
    <collection role="ddc" number="61">Medizin und Gesundheit</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCHST">Regensburg Center of Health Sciences and Technology - RCHST</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="oaweg" number="">Hybrid Open Access - OA-Veröffentlichung in einer Subskriptionszeitschrift/-medium</collection>
    <collection role="oaweg" number="">Corresponding author der OTH Regensburg</collection>
    <collection role="funding" number="">Publikationsfonds der OTH Regensburg</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
    <thesisPublisher>Ostbayerische Technische Hochschule Regensburg</thesisPublisher>
    <file>https://opus4.kobv.de/opus4-oth-regensburg/files/5779/1-s2.0-S0010482523000501-main.pdf</file>
  </doc>
  <doc>
    <id>660</id>
    <completedYear/>
    <publishedYear>2020</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>141</pageFirst>
    <pageLast>157</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
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    <completedDate>2020-10-23</completedDate>
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    <title language="eng">Semi-supervised Segmentation Based on Error-Correcting Supervision</title>
    <abstract language="eng">Pixel-level classification is an essential part of computer vision. For learning from labeled data, many powerful deep learning models have been developed recently. In this work, we augment such supervised segmentation models by allowing them to learn from unlabeled data. Our semi-supervised approach, termed Error-Correcting Supervision, leverages a collaborative strategy. Apart from the supervised training on the labeled data, the segmentation network is judged by an additional network. The secondary correction network learns on the labeled data to optimally spot correct predictions, as well as to amend incorrect ones. As auxiliary regularization term, the corrector directly influences the supervised training of the segmentation network. On unlabeled data, the output of the correction network is essential to create a proxy for the unknown truth. The corrector’s output is combined with the segmentation network’s prediction to form the new target. We propose a loss function that incorporates both the pseudo-labels as well as the predictive certainty of the correction network. Our approach can easily be added to supervised segmentation models. We show consistent improvements over a supervised baseline on experiments on both the Pascal VOC 2012 and the Cityscapes datasets with varying amounts of labeled data.</abstract>
    <parentTitle language="eng">Computer vision - ECCV 2020: 16th European conference, Glasgow, UK, August 23-28, 2020, Proceedings, Part XXIX</parentTitle>
    <identifier type="isbn">978-3-030-58525-9</identifier>
    <identifier type="doi">10.1007/978-3-030-58526-6_9</identifier>
    <enrichment key="OtherSeries">Lecture Notes in Computer Science; 12374</enrichment>
    <enrichment key="ConferenceStatement">European Conference on Computer Vision, 16th, 2020</enrichment>
    <enrichment key="BegutachtungStatus">peer-reviewed</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Robert Mendel</author>
    <author>Luis Antonio de Souza Jr.</author>
    <author>David Rauber</author>
    <author>João Paulo Papa</author>
    <author>Christoph Palm</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Semi-Supervised Learning</value>
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    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Machine Learning</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="institutes" number="RCHST">Regensburg Center of Health Sciences and Technology - RCHST</collection>
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    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
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    <pageLast>6</pageLast>
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    <publisherName>IEEE</publisherName>
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    <title language="eng">LiwTERM: A Lightweight Transformer-Based Model for Dermatological Multimodal Lesion Detection</title>
    <abstract language="eng">Skin cancer is the most common type of cancer in the world, accounting for approximately 30% of all diagnosed tumors. Early diagnosis reduces mortality rates and prevents disfiguring effects in different body regions. In recent years, machine learning techniques, particularly deep learning, have shown promising results in this task, presenting studies that have demonstrated that combining a patient’s clinical information with images of the lesion is crucial for improving the classification of skin lesions. Despite that, meaningful use of clinical information with multiple images is mandatory, requiring further investigation. Thus, this project aims to contribute to developing multimodal machine learning-based models to cope with the skin lesion classification task employing a lightweight transformer model. As a main hypothesis, models can take multiple images from different sources as input, along with clinical information from the patient’s history, leading to a more reliable diagnosis. Our model deals with the not-trivial task of combining images and clinical information (from anamneses) concerning the skin lesions in a lightweight transformer architecture that does not demand high computation resources but still presents competitive classification results.</abstract>
    <parentTitle language="eng">2024 37th SIBGRAPI Conference on Graphics, Patterns and Images (SIBGRAPI), Manaus, Brazil, 9/30/2024 - 10/3/2024</parentTitle>
    <identifier type="isbn">979-8-3503-7603-6</identifier>
    <identifier type="doi">10.1109/SIBGRAPI62404.2024.10716324</identifier>
    <enrichment key="opus.import.date">2024-11-18T10:16:05+00:00</enrichment>
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    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Luis A. Souza</author>
    <author>André G.C. Pacheco</author>
    <author>Gabriel G. de Angelo</author>
    <author>Thiago Oliveira-Santos</author>
    <author>Christoph Palm</author>
    <author>João Paulo Papa</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Lightweight Architectures</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Trans- formers</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Skin Lesion Detection</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Deep learning</value>
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    <collection role="institutes" number="FakIM">Fakultät Informatik und Mathematik</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
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    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
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    <publishedYear>2021</publishedYear>
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    <language>eng</language>
    <pageFirst>205</pageFirst>
    <pageLast>210</pageLast>
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    <publisherName>Springer Vieweg</publisherName>
    <publisherPlace>Wiesbaden</publisherPlace>
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    <belongsToBibliography>0</belongsToBibliography>
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    <title language="eng">Fine-tuning Generative Adversarial Networks using Metaheuristics</title>
    <abstract language="eng">Barrett's esophagus denotes a disorder in the digestive system that affects the esophagus' mucosal cells, causing reflux, and showing potential convergence to esophageal adenocarcinoma if not treated in initial stages. Thus, fast and reliable computer-aided diagnosis becomes considerably welcome. Nevertheless, such approaches usually suffer from imbalanced datasets, which can be addressed through Generative Adversarial Networks (GANs). Such techniques generate realistic images based on observed samples, even though at the cost of a proper selection of its hyperparameters. Many works employed a class of nature-inspired algorithms called metaheuristics to tackle the problem considering distinct deep learning approaches. Therefore, this paper's main contribution is to introduce metaheuristic techniques to fine-tune GANs in the context of Barrett's esophagus identification, as well as to investigate the feasibility of generating high-quality synthetic images for early-cancer assisted identification.</abstract>
    <parentTitle language="eng">Bildverarbeitung für die Medizin 2021. Proceedings, German Workshop on Medical Image Computing, Regensburg, March 7-9, 2021</parentTitle>
    <subTitle language="eng">A Case Study on Barrett's Esophagus Identification</subTitle>
    <identifier type="isbn">978-3-658-33197-9</identifier>
    <identifier type="doi">10.1007/978-3-658-33198-6_50</identifier>
    <enrichment key="opus.source">publish</enrichment>
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    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Luis Antonio de Souza Jr.</author>
    <author>Leandro A. Passos</author>
    <author>Robert Mendel</author>
    <author>Alanna Ebigbo</author>
    <author>Andreas Probst</author>
    <author>Helmut Messmann</author>
    <author>Christoph Palm</author>
    <author>João Paulo Papa</author>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Endoskopie</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Computerunterstützte Medizin</value>
    </subject>
    <subject>
      <language>deu</language>
      <type>swd</type>
      <value>Deep Learning</value>
    </subject>
    <collection role="ddc" number="0">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="ddc" number="6">Technik, Medizin, angewandte Wissenschaften</collection>
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    <collection role="institutes" number="RCHST">Regensburg Center of Health Sciences and Technology - RCHST</collection>
    <collection role="persons" number="palmremic">Palm, Christoph (Prof. Dr.) - ReMIC</collection>
    <collection role="persons" number="palmbarrett">Palm, Christoph (Prof. Dr.) - Projekt Barrett</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Regensburg Medical Image Computing (ReMIC)</collection>
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