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  <doc>
    <id>5399</id>
    <completedYear/>
    <publishedYear>2011</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>107</pageFirst>
    <pageLast>128</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>116</volume>
    <type>bookpart</type>
    <publisherName>Springer</publisherName>
    <publisherPlace>Berlin, Heidelberg</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Magnetic Resonance Imaging and Computational Fluid Dynamics of High Frequency Oscillatory Ventilation (HFOV)</title>
    <abstract language="eng">In order to better understand the mechanisms of gas transport during High Frequency Oscillatory Ventilation (HFOV) Magnetic Resonance Imaging (MRI) with contrast gases and numerical flow simulations based on Computational Fluid Dynamics(CFD) methods are performed. Validation of these new techniques is conducted by comparing the results obtained with simplified models of the trachea and a first lung bifurcation as well as in a cast model of the upper central airways with results achieved from conventional fluid mechanical measurement techniques like e.g. Laser Doppler Anemometry (LDA). Further it is demonstrated that MRI of experimental HFOV is feasible and that Hyperpolarized 3He allows for imaging the gas re-distribution inside the lung. Finally, numerical results of oscillatory flow in a 3rd generation model of the lung as well as the impact of endotracheal tubes on the flow regime development in a trachea model are presented.</abstract>
    <parentTitle language="eng">Fundamental Medical and Engineering Investigations on Protective Artificial Respiration</parentTitle>
    <identifier type="isbn">978-3-642-20325-1</identifier>
    <identifier type="doi">10.1007/978-3-642-20326-8_7</identifier>
    <identifier type="old">978-3-642-20326-8</identifier>
    <enrichment key="opus.import.date">2022-08-24T10:21:08+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="OtherSeries">Notes on Numerical Fluid Mechanics and Multidisciplinary Design ; 116</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Alexander-Wigbert K. Scholz</author>
    <author>Lars Krenkel</author>
    <author>Maxim Terekhov</author>
    <author>Janet Friedrich</author>
    <author>Julien Rivoire</author>
    <author>Rainer Köbrich</author>
    <author>Ursula Wolf</author>
    <author>Daniel Kalthoff</author>
    <author>Matthias David</author>
    <author>Claus Wagner</author>
    <author>Laura Maria Schreiber</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Central Airway</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>computational fluid dynamics</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Computational Fluid Dynamics Simulation</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Laser Doppler Anemometry</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Magnetic Resonance Imaging Measurement</value>
    </subject>
    <collection role="institutes" number="FAKMB">Fakultät Maschinenbau</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
    <collection role="institutes" number="">Labor Biofluidmechanik</collection>
    <collection role="persons" number="krenkellbfmbeitr">Krenkel, Lars (Prof. Dr.), Beitraege - Labor Biofluidmechanik</collection>
  </doc>
  <doc>
    <id>5391</id>
    <completedYear/>
    <publishedYear>2010</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>107</pageFirst>
    <pageLast>114</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>TUDpress</publisherName>
    <publisherPlace>Dresden</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Optimierung der Hochfrequenz-Oszillationsventilation mittels strömungsmechanischer Methoden und kontrastgasgestützter Magnetresonanztomografie - Teilprojekt: Rekonstruktion von Geometrien aus medizinischen Bilddaten und Erstellung von Modellen für experimentelle Strömungsuntersuchungen</title>
    <abstract language="deu">Der vorliegende Artikel skizziert die neu entwickelte Prozesskette für detailgenaue Rekonstruktion von Geometrien anhand medizinischer Bilddaten sowie die Herstellung von transparenten Modellen für experimentelle Untersuchungen mit bildgebenden Strömungsmessverfahren. Die Geometriedaten und Modelle werden für systematische Untersuchungen der komplexen Transportvorgänge in den Atemwegen bei künstlicher Beatmung mittels Hochfrequenzoszillationsventilation (HFOV) verwendet.</abstract>
    <parentTitle language="deu">Laseranwendung in der Medizin, Erfassen und Verarbeiten kardiovaskulärer Signale, protektive Beatmungskonzepte : 3. Dresdner Medizintechnik-Symposium - mit DFG-Forschungsschwerpunkt Protektive Beatmungskonzepte, 6. bis 9. Dezember 2010, Dresden</parentTitle>
    <identifier type="isbn">978-3-942710-02-2</identifier>
    <identifier type="url">https://elib.dlr.de/66863/</identifier>
    <enrichment key="opus.import.date">2022-08-24T10:21:08+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="OtherSeries">Dresdner Beiträge zur Medizintechnik ; 10</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Lars Krenkel</author>
    <author>Julien Pennecot</author>
    <author>Christian Lenz</author>
    <author>Daniel Feldmann</author>
    <author>Claus Wagner</author>
    <collection role="institutes" number="FAKMB">Fakultät Maschinenbau</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="krenkellbfmconf">Krenkel, Lars (Prof. Dr.), Präsentationen - Labor Biofluidmechanik</collection>
    <collection role="othforschungsschwerpunkt" number="16316">Produktion und Systeme</collection>
    <collection role="institutes" number="">Labor Biofluidmechanik</collection>
  </doc>
  <doc>
    <id>5299</id>
    <completedYear/>
    <publishedYear>2013</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>21</volume>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation>International Society for Magnetic Resonance in Medicine</creatingCorporation>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">19F Gas Flow Measurement of C3F7H During Constant Flow and High Frequency Oscillatory Ventilation</title>
    <abstract language="eng">The aim of the current study is the development of MRI methods that enable the investigation of gas flow mechanisms during high frequency oscillatory ventilation. This work includes flow measurements during three constant flows (19.9, 30.6 and 41.4 L min-1) and the comparison to direct numerical simulations (DNS) using a second-order-acurate finite-volume method and to data measured with a volume flow meter. 19F-MRI, DNS and flow meter data are in good agreement. Flow measurements during HFOV of 4 Hz were successfully performed and velocity profiles could be recorded at different phases of the ventilation cycle.</abstract>
    <parentTitle language="eng">Discovery, innovation &amp; application - advancing mr for improved health : ISMRM 21st Annual Meeting &amp; Exhibition ; SMRT 22nd Annual Meeting Salt Lake City, Utah, USA 20-26 April 2013</parentTitle>
    <identifier type="url">https://archive.ismrm.org/2013/1482.html</identifier>
    <enrichment key="opus.import.date">2022-08-24T10:21:08+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Janet Friedrich</author>
    <author>Daniel Feldmann</author>
    <author>Lars Krenkel</author>
    <author>Claus Wagner</author>
    <author>Laura Maria Schreiber</author>
    <collection role="institutes" number="FAKMB">Fakultät Maschinenbau</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="krenkellbfmconf">Krenkel, Lars (Prof. Dr.), Präsentationen - Labor Biofluidmechanik</collection>
    <collection role="othforschungsschwerpunkt" number="16316">Produktion und Systeme</collection>
    <collection role="institutes" number="">Labor Biofluidmechanik</collection>
  </doc>
  <doc>
    <id>5392</id>
    <completedYear/>
    <publishedYear>2010</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>505</pageFirst>
    <pageLast>512</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>Springer Berlin Heidelberg</publisherName>
    <publisherPlace>Berlin, Heidelberg</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Protective Artificial Lung Ventilation: Impact of an Endotracheal Tube on the Flow in a Generic Trachea</title>
    <abstract language="eng">Computational Fluid Dynamics (CFD) and experimental investigations on a generic model of the trachea have been carried out focusing on the impact of an endotracheal tube (ETT) on the resulting flow regime. It could be shown that detailed modelling of the airway management devices is essential for proper flow prediction, but secondary details as Murphy Eyes can be neglected. Models with bending and connector promote the formation of stronger secondary flows and disturbances which persist for a longer time.</abstract>
    <parentTitle language="eng">New Results in Numerical and Experimental Fluid Mechanics VII : Contributions to the 16th STAB/DGLR Symposium Aachen, Germany 2008</parentTitle>
    <identifier type="isbn">978-3-642-14242-0</identifier>
    <identifier type="doi">10.1007/978-3-642-14243-7_62</identifier>
    <identifier type="old">978-3-642-14243-7</identifier>
    <enrichment key="opus.import.date">2022-08-24T10:21:08+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="OtherSeries">Notes on Numerical Fluid Mechanics and Multidisciplinary Design ; 112</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Lars Krenkel</author>
    <author>Claus Wagner</author>
    <author>Ursula Wolf</author>
    <author>Alexander-Wigbert K. Scholz</author>
    <author>Maxim Terekhov</author>
    <author>Julien Rivoire</author>
    <author>W. Schreiber</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>computational fluid dynamics</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Computational Fluid Dynamics Simulation</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Endotracheal Tube</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Particle Image Velocimetry</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Turbulent Kinetic Energy</value>
    </subject>
    <collection role="institutes" number="FAKMB">Fakultät Maschinenbau</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="krenkellbfmconf">Krenkel, Lars (Prof. Dr.), Präsentationen - Labor Biofluidmechanik</collection>
    <collection role="othforschungsschwerpunkt" number="16314">Lebenswissenschaften und Ethik</collection>
    <collection role="institutes" number="">Labor Biofluidmechanik</collection>
  </doc>
  <doc>
    <id>5300</id>
    <completedYear/>
    <publishedYear>2010</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>18</volume>
    <type>conferencepresentation</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Exploration of Gas Flow During High Frequency Oscillated Ventilation by 19F-Gas-MRI</title>
    <abstract language="eng">To detect convective gas flow inside the large airways during high frequency oscillated ventilation (HFOV) the fluorinated contrast gas Heptafluoropropane was used for 19F-MRI. In a first study the comparison between constant flow measurements and Computational Fluid Dynamics (CFD) simulations provided a good agreement. In a following experiment oscillated flow was applied to a lung phantom consisting of ventilation bag and long pipe. The pressure wave inside the pipe was explored point-by-point and corresponding velocities were determined. With these experiments it could be shown for the first time that flow measurement during HFOV using fluorinated contrast gas is feasible.</abstract>
    <parentTitle language="eng">Proceedings of the International Society for Magnetic Resonance in Medicine</parentTitle>
    <identifier type="url">https://archive.ismrm.org/2010/2527.html</identifier>
    <enrichment key="opus.import.date">2022-08-24T10:21:08+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Janet Friedrich</author>
    <author>Julien Rivoire</author>
    <author>Alexander-Wigbert K. Scholz</author>
    <author> Wiegbert</author>
    <author>Maxim Terekov</author>
    <author>Rainer Kbrich</author>
    <author>Lars Krenkel</author>
    <author>Claus Wagner</author>
    <author>Laura Maria Schreiber</author>
    <collection role="institutes" number="FAKMB">Fakultät Maschinenbau</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="krenkellbfmconf">Krenkel, Lars (Prof. Dr.), Präsentationen - Labor Biofluidmechanik</collection>
    <collection role="othforschungsschwerpunkt" number="16316">Produktion und Systeme</collection>
    <collection role="institutes" number="">Labor Biofluidmechanik</collection>
  </doc>
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