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  <doc>
    <id>5399</id>
    <completedYear/>
    <publishedYear>2011</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>107</pageFirst>
    <pageLast>128</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>116</volume>
    <type>bookpart</type>
    <publisherName>Springer</publisherName>
    <publisherPlace>Berlin, Heidelberg</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Magnetic Resonance Imaging and Computational Fluid Dynamics of High Frequency Oscillatory Ventilation (HFOV)</title>
    <abstract language="eng">In order to better understand the mechanisms of gas transport during High Frequency Oscillatory Ventilation (HFOV) Magnetic Resonance Imaging (MRI) with contrast gases and numerical flow simulations based on Computational Fluid Dynamics(CFD) methods are performed. Validation of these new techniques is conducted by comparing the results obtained with simplified models of the trachea and a first lung bifurcation as well as in a cast model of the upper central airways with results achieved from conventional fluid mechanical measurement techniques like e.g. Laser Doppler Anemometry (LDA). Further it is demonstrated that MRI of experimental HFOV is feasible and that Hyperpolarized 3He allows for imaging the gas re-distribution inside the lung. Finally, numerical results of oscillatory flow in a 3rd generation model of the lung as well as the impact of endotracheal tubes on the flow regime development in a trachea model are presented.</abstract>
    <parentTitle language="eng">Fundamental Medical and Engineering Investigations on Protective Artificial Respiration</parentTitle>
    <identifier type="isbn">978-3-642-20325-1</identifier>
    <identifier type="doi">10.1007/978-3-642-20326-8_7</identifier>
    <identifier type="old">978-3-642-20326-8</identifier>
    <enrichment key="opus.import.date">2022-08-24T10:21:08+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <enrichment key="OtherSeries">Notes on Numerical Fluid Mechanics and Multidisciplinary Design ; 116</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Alexander-Wigbert K. Scholz</author>
    <author>Lars Krenkel</author>
    <author>Maxim Terekhov</author>
    <author>Janet Friedrich</author>
    <author>Julien Rivoire</author>
    <author>Rainer Köbrich</author>
    <author>Ursula Wolf</author>
    <author>Daniel Kalthoff</author>
    <author>Matthias David</author>
    <author>Claus Wagner</author>
    <author>Laura Maria Schreiber</author>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Central Airway</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>computational fluid dynamics</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Computational Fluid Dynamics Simulation</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Laser Doppler Anemometry</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>Magnetic Resonance Imaging Measurement</value>
    </subject>
    <collection role="institutes" number="FAKMB">Fakultät Maschinenbau</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="othforschungsschwerpunkt" number="16311">Digitalisierung</collection>
    <collection role="institutes" number="">Labor Biofluidmechanik</collection>
    <collection role="persons" number="krenkellbfmbeitr">Krenkel, Lars (Prof. Dr.), Beitraege - Labor Biofluidmechanik</collection>
  </doc>
  <doc>
    <id>5300</id>
    <completedYear/>
    <publishedYear>2010</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>18</volume>
    <type>conferencepresentation</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Exploration of Gas Flow During High Frequency Oscillated Ventilation by 19F-Gas-MRI</title>
    <abstract language="eng">To detect convective gas flow inside the large airways during high frequency oscillated ventilation (HFOV) the fluorinated contrast gas Heptafluoropropane was used for 19F-MRI. In a first study the comparison between constant flow measurements and Computational Fluid Dynamics (CFD) simulations provided a good agreement. In a following experiment oscillated flow was applied to a lung phantom consisting of ventilation bag and long pipe. The pressure wave inside the pipe was explored point-by-point and corresponding velocities were determined. With these experiments it could be shown for the first time that flow measurement during HFOV using fluorinated contrast gas is feasible.</abstract>
    <parentTitle language="eng">Proceedings of the International Society for Magnetic Resonance in Medicine</parentTitle>
    <identifier type="url">https://archive.ismrm.org/2010/2527.html</identifier>
    <enrichment key="opus.import.date">2022-08-24T10:21:08+00:00</enrichment>
    <enrichment key="opus.source">sword</enrichment>
    <enrichment key="opus.import.user">importuser</enrichment>
    <licence>Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG</licence>
    <author>Janet Friedrich</author>
    <author>Julien Rivoire</author>
    <author>Alexander-Wigbert K. Scholz</author>
    <author> Wiegbert</author>
    <author>Maxim Terekov</author>
    <author>Rainer Kbrich</author>
    <author>Lars Krenkel</author>
    <author>Claus Wagner</author>
    <author>Laura Maria Schreiber</author>
    <collection role="institutes" number="FAKMB">Fakultät Maschinenbau</collection>
    <collection role="othpublikationsherkunft" number="">Externe Publikationen</collection>
    <collection role="persons" number="krenkellbfmconf">Krenkel, Lars (Prof. Dr.), Präsentationen - Labor Biofluidmechanik</collection>
    <collection role="othforschungsschwerpunkt" number="16316">Produktion und Systeme</collection>
    <collection role="institutes" number="">Labor Biofluidmechanik</collection>
  </doc>
</export-example>
