@article{EbigboMendelProbstetal., author = {Ebigbo, Alanna and Mendel, Robert and Probst, Andreas and Manzeneder, Johannes and Souza Jr., Luis Antonio de and Papa, Jo{\~a}o Paulo and Palm, Christoph and Messmann, Helmut}, title = {Computer-aided diagnosis using deep learning in the evaluation of early oesophageal adenocarcinoma}, series = {GuT}, volume = {68}, journal = {GuT}, number = {7}, publisher = {British Society of Gastroenterology}, doi = {10.1136/gutjnl-2018-317573}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-68}, pages = {1143 -- 1145}, abstract = {Computer-aided diagnosis using deep learning (CAD-DL) may be an instrument to improve endoscopic assessment of Barrett's oesophagus (BE) and early oesophageal adenocarcinoma (EAC). Based on still images from two databases, the diagnosis of EAC by CAD-DL reached sensitivities/specificities of 97\%/88\% (Augsburg data) and 92\%/100\% (Medical Image Computing and Computer-Assisted Intervention [MICCAI] data) for white light (WL) images and 94\%/80\% for narrow band images (NBI) (Augsburg data), respectively. Tumour margins delineated by experts into images were detected satisfactorily with a Dice coefficient (D) of 0.72. This could be a first step towards CAD-DL for BE assessment. If developed further, it could become a useful adjunctive tool for patient management.}, subject = {Speiser{\"o}hrenkrebs}, language = {en} } @article{HeberlHofrichterRanketal., author = {Heberl, Michael and Hofrichter, Andreas and Rank, Daniel and Bauer, Franz and Sterner, Michael}, title = {Influence of plant dimensioning and location on the ecology of PEM electrolysis}, series = {International Journal of Hydrogen Energy}, volume = {167}, journal = {International Journal of Hydrogen Energy}, publisher = {Elsevier}, issn = {0360-3199}, doi = {10.1016/j.ijhydene.2025.151039}, pages = {11}, abstract = {PV and wind systems with PEM electrolysis offer great potential for producing hydrogen with low emissions. Our research has identified the ecologically optimal size of PEM in relation to fixed PV/wind capacities. We calculate efficiencies and production volumes for PEM with 240 capacity and site variations. We analyse the global warming potential of all systems and draw conclusions about the optimal system design. The lowest GWP is achieved at the site with the highest full load hours with 1.32 kg CO2-eq/kg H2 (Wind, 28 MW electrolysis) and 4.24 kg CO2-eq/kg H2 (PV, 23 MW electrolysis). We have identified a clear trend: increasing PV/wind full load hours leads to higher ideal PEM capacities. However, there is a significant discrepancy between the ideal economic and ecological capacity. Furthermore, higher electrolysis capacities can achieve lower emissions as they increasingly operate at a more efficient partial load.}, language = {en} } @article{HantschWestnerMatschi, author = {Hantsch, Carolin and Westner, Markus and Matschi, Markus}, title = {IT/OT-Konvergenz: Status-Quo und Umsetzungsempfehlungen}, series = {HMD Praxis der Wirtschaftsinformatik}, journal = {HMD Praxis der Wirtschaftsinformatik}, publisher = {Springer Nature}, doi = {10.1365/s40702-024-01111-1}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-77937}, pages = {16}, abstract = {Organisationen machen große Anstrengungen zur Verbesserung ihrer Ambidextrie, d. h. ihrer F{\"a}higkeit sowohl Exploitationsziele (z. B. Effizienz, Vorhersagbarkeit) als auch Explorationsziele (z. B. Anpassbarkeit, Innovation) zu erreichen. Obwohl gem{\"a}ß der Praxisliteratur Technologie in Software-Projekten dabei eine zentrale Rolle spielen kann, gibt es kaum Forschung dazu, wie technologische Faktoren Ambidexterie in Software-Projekten beeinflussen. In dieser Studie untersuchen wir die Rolle dreier technologischer Faktoren: kontinuierliche Integration, Standardisierung und Microservice-Architektur. Die Ergebnisse einer Mehrinformanten-Umfrage in 95 Projekten in der Schweiz und D{\"a}nemark zeigen, dass kontinuierliche Integration und Standardisierung mit h{\"o}herer Ambidexterie einhergehen, w{\"a}hrend der Zusammenhang zwischen Microservice-Architektur und Ambidextrie nicht signifikant ist. Unser Artikel geht {\"u}ber die existierende Forschung hinaus, indem er zeigt, dass kontinuierliche Integration und Standardisierung nicht nur Exploitation, sondern auch Exploration f{\"o}rdern k{\"o}nnen. Wir diskutieren auch Gr{\"u}nde f{\"u}r den insignifikanten Zusammenhang zwischen Microservice-Architektur und Ambidextrie.}, language = {de} } @article{TroesterEcksteinKenneletal., author = {Tr{\"o}ster, Mark and Eckstein, Simon and Kennel, Paula and Kopp, Verna and Benkiser, Alina and Bihlmeier, Felicitas and Daub, Urban and Maufroy, Christophe and Dendorfer, Sebastian and Fritzsche, Lars and Schneider, Urs and Bauernhasl, Thomas}, title = {Person-specific evaluation method for occupational exoskeletons - Biomechanical body heat map}, series = {Applied Ergonomics}, volume = {132}, journal = {Applied Ergonomics}, publisher = {Elsevier}, doi = {10.1016/j.apergo.2025.104671}, pages = {30}, abstract = {Human-centred and ergonomic work design is one of the most important drivers for increasing the competitiveness of the European Union. As a flexible, person-specific occupational measure, exoskeletons promise great potential for effectively reducing individual ergonomic stress. Digital human models can provide important insights and offer great potential for systematising the effect and targeted use of exoskeletons, supporting their effective implementation in practice. In this article, digital human models are applied on two levels. Firstly, a realistic industrial logistics scenario in which boxes had to be relocated is designed with the help of a digital human model for workplace and process planning and secondly, a new biomechanical evaluation methodology to analyse intended and unintended effects on internal stress on the human body is demonstrated by applying musculoskeletal exoskeleton human models of four test subjects. Finally, the modelled biomechanical support tendencies of one exoskeleton are preliminary validated using EMG measurement data of the back muscles collected from the four male workers. The preliminary analysis of two back-support exoskeletons to demonstrate the new methodological approach confirms the expected, intended effects in the lower back and reveals unintended effects, such as e.g. changes in knee kinetics when applying a soft or hard-frame exoskeleton. Furthermore, the exemplary results to demonstrate the methodological approach expose notable differences between the test subjects, which underlines the relevance of person-specific evaluation and consideration of exoskeleton support. The preliminary validation shows a correlation between the modelled and the EMG-measured biomechanical exoskeleton support of the considered back muscles.}, language = {en} } @article{RoghaniRomeisGlavanetal., author = {Roghani, Mehran and Romeis, Dirk and Glavan, Gašper and Belyaeva, Inna A. and Shamonin (Chamonine), Mikhail and Saphiannikova, Marina}, title = {Magnetically induced deformation of isotropic magnetoactive elastomers and its relation to the magnetorheological effect}, series = {Physical Review Applied}, volume = {23}, journal = {Physical Review Applied}, number = {3}, publisher = {American Physical Society (APS)}, issn = {2331-7019}, doi = {10.1103/PhysRevApplied.23.034041}, abstract = {Can isotropic magnetoactive elastomers (MAEs) undergo giant magnetically induced deformations and exhibit huge magnetorheological effects simultaneously? In this experimental and theoretical study, we reveal how the macroscopic deformation of MAEs relates to the process of particle restructuring caused by application of a magnetic field. For this purpose, MAE cylinders with different aspect ratios and particle loadings are studied in uniform magnetic fields. The axial deformations of the cylinders are acquired using an optical camera. A unified mean-field model proposed in previous studies is adapted to describe the transition of initially isotropic cylinders into transversely isotropic ones. This mechanical transition is caused by the rearrangement of particles into dense columnar structures aligned with the field and is believed to result in a huge magnetorheological effect. Our model however predicts less than a threefold increase in elastic moduli when evaluated along the field direction. This prediction is based on a careful examination of the shear moduli of studied MAEs and the columnar structures. A weak magnetorheological effect explains significant axial deformations measured in the field direction. A strong magnetorheological effect would hinder axial deformations due to an increase in the modulus by several orders of magnitude. Not only are the moduli and macroscopic deformations influenced by microstructure evolution, but so is the magnetization of particles, which increases as they rearrange into dense columns. With this study, we show that the unified mean-field model provides quantitative access to hidden material properties such as magnetization and stiffness in MAE samples with different shapes and evolving microstructures. Published by the American Physical Society 2025}, language = {en} } @article{BedburKampsSchmiedt, author = {Bedbur, Stefan and Kamps, Udo and Schmiedt, Anja Bettina}, title = {A flexible model of ordered random variables for non-metallic inclusions in steels and related statistical inference}, series = {Applied Mathematical Modelling}, volume = {149}, journal = {Applied Mathematical Modelling}, publisher = {Elsevier}, issn = {0307-904X}, doi = {10.1016/j.apm.2025.116284}, pages = {15}, abstract = {In a data set of non-metallic inclusion sizes in samples from engineering steel, common order statistics fail to serve as a suitable model for ascendingly ordered measurements within single samples. Therefore, a flexible model of ordered random variables is proposed, which allows for changes of distributions described by model parameters. Joint maximum likelihood estimation of these parameters and the shape parameter of an underlying left-truncated Weibull distribution is considered, and a model test is developed for the null-hypothesis of common order statistics being an adequate model. To overcome small data situations, a link-function approach is examined in order to reduce the number of involved model parameters as well as to propose to use a link-function parameter as a material indicator. An asymptotic test is provided to check for the presence of a linear link function, and tests for hypotheses about two link-function parameters are studied. Moreover, the construction of simultaneous confidence regions for the link-function parameters as well as of confidence bands for the entire graph of the link function are presented. Throughout, the findings are applied to the real metallurgical data set. Similar problems and data structures arise in other fields of material science and applications such as geology.}, language = {en} } @inproceedings{FranzWinkerGroppeetal., author = {Franz, Maja and Winker, Tobias and Groppe, Sven and Mauerer, Wolfgang}, title = {Hype or Heuristic? Quantum Reinforcement Learning for Join Order Optimisation}, series = {2024 IEEE International Conference on Quantum Computing and Engineering (QCE), 15-20 September 2024, Montreal, QC, Canada}, booktitle = {2024 IEEE International Conference on Quantum Computing and Engineering (QCE), 15-20 September 2024, Montreal, QC, Canada}, publisher = {IEEE}, doi = {10.1109/QCE60285.2024.00055}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-76877}, pages = {409 -- 420}, abstract = {Identifying optimal join orders (JOs) stands out as a key challenge in database research and engineering. Owing to the large search space, established classical methods rely on approximations and heuristics. Recent efforts have successfully explored reinforcement learning (RL) for JO. Likewise, quantum versions of RL have received considerable scientific attention. Yet, it is an open question if they can achieve sustainable, overall practical advantages with improved quantum processors. In this paper, we present a novel approach that uses quantum reinforcement learning (QRL) for JO based on a hybrid variational quantum ansatz. It is able to handle general bushy join trees instead of resorting to simpler left-deep variants as compared to approaches based on quantum(-inspired) optimisation, yet requires multiple orders of magnitudes fewer qubits, which is a scarce resource even for post-NISQ systems. Despite moderate circuit depth, the ansatz exceeds current NISQ capabilities, which requires an evaluation by numerical simulations. While QRL may not significantly outperform classical approaches in solving the JO problem with respect to result quality (albeit we see parity), we find a drastic reduction in required trainable parameters. This benefits practically relevant aspects ranging from shorter training times compared to classical RL, less involved classical optimisation passes, or better use of available training data, and fits data-stream and low-latency processing scenarios. Our comprehensive evaluation and careful discussion delivers a balanced perspective on possible practical quantum advantage, provides insights for future systemic approaches, and allows for quantitatively assessing trade-offs of quantum approaches for one of the most crucial problems of database management systems.}, language = {en} } @article{SchummHaasPeeretal., author = {Schumm, Leon and Haas, Jannik and Peer, Rebecca and Sterner, Michael}, title = {The role of hydrogen offtaker regulation in highly renewable electricity systems}, series = {Energy}, volume = {342}, journal = {Energy}, publisher = {Elsevier}, doi = {10.1016/j.energy.2025.139513}, pages = {13}, abstract = {The growing demand for green hydrogen necessitates a rapid scale-up of production and exports to meet decarbonization targets globally. However, current ramp-up efforts remain insufficient, calling for policies that unlock the potential of hydrogen as a low-carbon energy carrier. A key lever is the offtaker regulation, which impacts the pace and sustainability of export projects. This study investigates minimum renewable share requirements for hydrogen exports in countries with high renewable electricity shares. Using New Zealand as a case study, we develop a fully sector-coupled capacity expansion and dispatch model, integrating hydrogen and electricity network planning based on PyPSA-Earth. The model optimizes New Zealand's energy system under varying export scenarios, renewable electricity shares, and resulting system impacts. We find that domestic electricity demand and renewable expansion rates dominate long-term outcomes, while progressive regulation enables short-term hydrogen and Power-to-X exports. Relaxing the renewable threshold from 80\% to 60\% triples export volumes from 2.5 TWh to 8.2 TWh by 2030. We propose a two-stage requirement: an initially progressive threshold to attract investment with low consequential emissions, followed by stricter regulation to prevent high emissions, rising domestic electricity prices, and declining hydrogen competitiveness. This framework, demonstrated for New Zealand, can guide hydrogen-exporting countries worldwide.}, language = {en} } @article{HollweckLeidingerHartmannetal., author = {Hollweck, Christoph and Leidinger, Lukas and Hartmann, Stefan and Wagner, Marcus and W{\"u}chner, Roland}, title = {An analysis of the critical time step size for explicit dynamics using trimmed B-splines, LR-splines, and THB-splines}, series = {Computer Methods in Applied Mechanics and Engineering}, volume = {450}, journal = {Computer Methods in Applied Mechanics and Engineering}, publisher = {Elsevier}, issn = {0045-7825}, doi = {10.1016/j.cma.2025.118656}, pages = {36}, abstract = {Isogeometric analysis (IGA) combined with explicit dynamics is increasingly used in academia and has already been successfully applied in industrial simulations, including crash and sheet-metal forming. Since explicit schemes are only conditionally stable, accurate estimation of the critical time step is essential for both stability and efficiency. Adaptive mesh refinement is widely used to balance accuracy and computational cost. In IGA, THB- and LR-splines break the tensor-product structure of standard B-splines and enable local refinement, but their effect on the critical time step under trimming has not been systematically studied - a key requirement for reliable time step estimation. We investigate the critical time step in explicit dynamic simulations using trimmed B-splines, LR-splines, and THB-splines, based on a lumped mass matrix obtained by simple row summation. One-dimensional bar, two-dimensional membrane, and trimmed shell models are analyzed to determine how trimming and local refinement influence element and system eigenfrequencies, which directly control the stable time step. Refined boundary elements in open knot vectors are identified as the main bottleneck. Trimming these elements can increase the stable time step, though certain trimming configurations introduce new restrictions. Results show that LR- and THB-splines impose time step constraints similar to B-splines, making them equally suitable for explicit simulations. We also present a general method for computing element-wise B{\´e}zier extraction operators for LR- and THB-splines, enabling straightforward integration into standard finite element solvers. The findings are validated through nonlinear sheet-metal forming simulations in LS-DYNA using shells discretized with trimmed B-, LR-, and THB-splines. This represents the first such application and demonstrates their practical feasibility for industrial use.}, language = {en} } @article{RueckertRauberMaerkletal., author = {Rueckert, Tobias and Rauber, David and Maerkl, Raphaela and Klausmann, Leonard and Yildiran, Suemeyye R. and Gutbrod, Max and Nunes, Danilo Weber and Moreno, Alvaro Fernandez and Luengo, Imanol and Stoyanov, Danail and Toussaint, Nicolas and Cho, Enki and Kim, Hyeon Bae and Choo, Oh Sung and Kim, Ka Young and Kim, Seong Tae and Arantes, Gon{\c{c}}alo and Song, Kehan and Zhu, Jianjun and Xiong, Junchen and Lin, Tingyi and Kikuchi, Shunsuke and Matsuzaki, Hiroki and Kouno, Atsushi and Manesco, Jo{\~a}o Renato Ribeiro and Papa, Jo{\~a}o Paulo and Choi, Tae-Min and Jeong, Tae Kyeong and Park, Juyoun and Alabi, Oluwatosin and Wei, Meng and Vercauteren, Tom and Wu, Runzhi and Xu, Mengya and Wang, An and Bai, Long and Ren, Hongliang and Yamlahi, Amine and Hennighausen, Jakob and Maier-Hein, Lena and Kondo, Satoshi and Kasai, Satoshi and Hirasawa, Kousuke and Yang, Shu and Wang, Yihui and Chen, Hao and Rodr{\´i}guez, Santiago and Aparicio, Nicol{\´a}s and Manrique, Leonardo and Palm, Christoph and Wilhelm, Dirk and Feussner, Hubertus and Rueckert, Daniel and Speidel, Stefanie and Nasirihaghighi, Sahar and Al Khalil, Yasmina and Li, Yiping and Arbel{\´a}ez, Pablo and Ayobi, Nicol{\´a}s and Hosie, Olivia and Lyons, Juan Camilo}, title = {Comparative validation of surgical phase recognition, instrument keypoint estimation, and instrument instance segmentation in endoscopy: Results of the PhaKIR 2024 challenge}, series = {Medical Image Analysis}, volume = {109}, journal = {Medical Image Analysis}, publisher = {Elsevier}, issn = {1361-8415}, doi = {10.1016/j.media.2026.103945}, pages = {31}, abstract = {Reliable recognition and localization of surgical instruments in endoscopic video recordings are foundational for a wide range of applications in computer- and robot-assisted minimally invasive surgery (RAMIS), including surgical training, skill assessment, and autonomous assistance. However, robust performance under real-world conditions remains a significant challenge. Incorporating surgical context - such as the current procedural phase - has emerged as a promising strategy to improve robustness and interpretability. To address these challenges, we organized the Surgical Procedure Phase, Keypoint, and Instrument Recognition (PhaKIR) sub-challenge as part of the Endoscopic Vision (EndoVis) challenge at MICCAI 2024. We introduced a novel, multi-center dataset comprising thirteen full-length laparoscopic cholecystectomy videos collected from three distinct medical institutions, with unified annotations for three interrelated tasks: surgical phase recognition, instrument keypoint estimation, and instrument instance segmentation. Unlike existing datasets, ours enables joint investigation of instrument localization and procedural context within the same data while supporting the integration of temporal information across entire procedures. We report results and findings in accordance with the BIAS guidelines for biomedical image analysis challenges. The PhaKIR sub-challenge advances the field by providing a unique benchmark for developing temporally aware, context-driven methods in RAMIS and offers a high-quality resource to support future research in surgical scene understanding.}, language = {en} } @article{KuettnerFischerLaumer, author = {Kuettner, Andreas and Fischer, Samuel and Laumer, Tobias}, title = {Mechanical and structural characterization of heat-staked parts realized by selective laser sintering of polyamide 12}, series = {The International Journal of Advanced Manufacturing Technology}, journal = {The International Journal of Advanced Manufacturing Technology}, publisher = {Springer}, doi = {10.1007/s00170-025-17319-4}, pages = {20}, abstract = {Heat staking is a joining process in which thermoplastic pins are formed by heat and pressure in a form-fitting and insoluble way. This study evaluates the mechanical performance and microstructure of selective laser sintered (SLS) polyamide 12 (PA 12) components before and after heat staking, compared with conventionally turned reference specimens. The components were characterized using tensile tests, micrographs, microscopy, and micro-CT measurements. For the tests, the forces and temperatures during heat staking were varied to determine the best process parameters. Tensile tests revealed that SLS joints achieved strengths of up to 33.6 MPa, approaching the 39.9 MPa of the turned references. Microstructural analysis showed a marked reduction in porosity due to heat staking. Porosity decreased from 3.9\% to 1.56\% at a staking force of 300 N and from 4.29\% to 0.81\% at 1000 N, highlighting the beneficial effect of increased force. These results demonstrate that heat staking parameters significantly influence local densification and mechanical performance, and that, under suitable conditions, SLS components can achieve joint strengths comparable to conventionally manufactured parts. The study shows that the heat staking process parameters have a significant influence on the local microstructure and thus on the mechanical performance and provides a basis for optimizing SLS components for new heat staking applications.}, language = {en} } @article{GrabingerHauserWolffetal., author = {Grabinger, Lisa and Hauser, Florian and Wolff, Christian and Mottok, J{\"u}rgen}, title = {On Eye Tracking in Software Engineering}, series = {SN Computer Science}, volume = {5}, journal = {SN Computer Science}, number = {6}, publisher = {Springer}, address = {Singapore}, issn = {2661-8907}, doi = {10.1007/s42979-024-03045-3}, abstract = {Eye tracking is becoming more and more important as a research method within the field of software engineering (SE). Existing meta-analyses focus on the design or conduct of SE eye tracking studies rather than the analysis phase. This article attempts to fill this gap; it presents a systematic literature review of eye tracking studies in the field of SE—focusing mainly on the data analysis methods used. From the IEEE Xplore and ACM digital libraries we gather 125 papers up to the first quarter of 2024. Detailed evaluation provides information on the number of papers that use specific methods of analysis (i.e., descriptive or inferential statistics, and gaze visualization) or settings (e.g., sample size, technical setup, and selected aspects of research design). With the data obtained we can infer the popularity of specific analysis methods in the field. Those results enable efficient work on data analysis tools or education of aspiring researchers and can serve as basis for standardization or guidelines within the community—providing for methods to include as well as current inconsistencies.}, language = {en} } @article{WeindlerLehnerEcksteinetal., author = {Weindler, Jeremy and Lehner, Hannes and Eckstein, J. and Dawoud, Belal}, title = {Performance assessment of a green hydrogen-based household energy system supported by a battery storage at different resolutions of the electrical load profile}, series = {International Journal of Hydrogen Energy}, volume = {144}, journal = {International Journal of Hydrogen Energy}, publisher = {Elsevier}, issn = {0360-3199}, doi = {10.1016/j.ijhydene.2025.04.431}, pages = {30 -- 41}, abstract = {Hydrogen deems quite suitable for medium- and long-term energy storage of surplus renewable electricity. Nowadays, all-in-one solutions consisting of an electrolyzer, a compressor, pressurized hydrogen storage tanks, a fuel cell (FC) and the necessary peripheral components are available for single family houses. This work presents a comparative assessment of the system's key performance indicators in a household system with three market available FCs with the nominal powers of 0.8, 1.4 and 7.8 kW. The design tool developed for the assessment of the hybrid energy system along with two energy management system configurations are introduced. An electrochemical and thermal model widely applied in the literature is used to model the FCs, which is validated against the available experimental data in the literature for all three FCs. The influence of the FCs' nominal power, their power dynamic operation range, the use of a battery storage with different capacities and the load profile's resolution have been technically assessed regarding the system's self-sufficiency (SS), the FC's efficiency, full-load operating hours, and number of on/off cycles. It turned out that, the system performance is strongly dependent on the nominal power of the FC and its power dynamic operation range. If no battery-storage is applied, the complete grid independence is not possible, and a high resolution of the load profile is indispensable in the assessment of the system design. A hybrid energy system comprising the 1.4 kW FC, a PV system of 10 kW peak power and a battery of 15 kW storage capacity showed a degree of SS of 98\%. The number of the full-load operating hours and on/off cycles of that FC amount to 768 and 116 cycles, respectively. Such promising results are referred to the high dynamic operation range of the battery, and its high discharge power capacity, which makes it more suitable to cover a remarkably higher fraction of the load deficit, if compared to a system without a battery.}, language = {en} }