@article{SchottKlempererLieb, author = {Schott, Gisela and Klemperer, David and Lieb, Klaus}, title = {Arzneimittel: Sinnvolle Studien nach der Zulassung}, series = {Deutsches {\"A}rzteblatt}, volume = {118}, journal = {Deutsches {\"A}rzteblatt}, number = {23}, publisher = {Deutscher {\"A}rzteverlag}, address = {Berlin}, pages = {A-1148 / B-945}, abstract = {Die Arzneimittelkommission der deutschen {\"A}rzteschaft erkl{\"a}rt, an welchen Postzulassungsstudien {\"A}rztinnen und {\"A}rzte teilnehmen sollten - und an welchen nicht.}, language = {de} } @article{WeberKrugHaugetal., author = {Weber, Karsten and Krug, Henriette and Haug, Sonja and K{\"u}hn, Andrea A. and Scharf, Anna}, title = {External Observations and Subjective Experiences: Metaphors Used by DBS Patients}, series = {AJOB Neuroscience}, volume = {14}, journal = {AJOB Neuroscience}, number = {3}, publisher = {Taylor\&Francis}, doi = {10.1080/21507740.2023.2246219}, pages = {323 -- 325}, language = {en} } @article{LempertSchottKoebberlingetal., author = {Lempert, Thomas and Schott, Gisela and K{\"o}bberling, Johannes and Klemperer, David and Lieb, Klaus}, title = {Fortbildungen: Keine Punkte bei Sponsoring}, series = {Deutsches {\"A}rzteblatt}, volume = {116}, journal = {Deutsches {\"A}rzteblatt}, number = {13}, publisher = {Deutscher {\"A}rzteverlag}, address = {Berlin}, pages = {A620 -- A621}, language = {de} } @incollection{LeuschCorstenGiordanoetal., author = {Leusch, Vera and Corsten, Sabine and Giordano, Katharina and Kreiter, Daniel and Lauer, Norina}, title = {Tablet-gest{\"u}tzte Biographiearbeit in Senioreneinrichtungen}, series = {Die Nachhaltigkeitsziele der UN im Spiegel der Wissenschaft}, booktitle = {Die Nachhaltigkeitsziele der UN im Spiegel der Wissenschaft}, editor = {Heese, Carl and Sch{\"u}tz, Sandra and Obergrießer, Stefanie}, publisher = {Springer VS}, address = {Wiesbaden}, isbn = {978-3-658-43333-8}, doi = {10.1007/978-3-658-43334-5_9}, pages = {143 -- 158}, abstract = {{\"A}ltere Menschen in Senioreneinrichtungen zeigen h{\"a}ufig ein eingeschr{\"a}nktes psychologisches Wohlbefinden. Biographisch-narrative Interventionen k{\"o}nnen Anpassungsprozesse unterst{\"u}tzen und Lebensqualit{\"a}t verbessern. Sowohl Einzel- als auch Gruppensitzungen k{\"o}nnen zu signifikanten Verbesserungen der Lebensqualit{\"a}t bei institutionalisierten Menschen im Alter f{\"u}hren, wobei besonders Gruppensitzungen zur F{\"o}rderung der sozialen Integration empfohlen werden. Dabei bieten digitale Medien die M{\"o}glichkeit, eigenst{\"a}ndig eine an kognitive und sensomotorische F{\"a}higkeiten angepasste Biographiearbeit durchzuf{\"u}hren. Digitale Medien und das Einbinden von Ehrenamtlichen k{\"o}nnen den Personalaufwand in Senioreneinrichtungen bei der Umsetzung von Biographiearbeit verringern und Pflegefachkr{\"a}fte entlasten. Es fehlen jedoch systematische Studien zu digital gest{\"u}tzter Biographiearbeit mit Bewohner*innen in Senioreneinrichtungen. In dem vom Bundesministerium f{\"u}r Bildung und Forschung (BMBF) gef{\"o}rderten Forschungsprojekt Biographiearbeit in Senioreneinrichtungen mit Tablet-Unterst{\"u}tzung zur Verbesserung von Lebensqualit{\"a}t und Kommunikation (BaSeTaLK) wurde daher untersucht, ob mit einer Tablet-gest{\"u}tzten Biographiearbeit die Lebensqualit{\"a}t von Bewohner*innen in Senioreneinrichtungen, im Sinne erh{\"o}hter sozialer und kommunikativer Teilhabe sowie Depressionspr{\"a}vention, gesteigert werden kann. Das Projekt, das von der OTH Regensburg und der Katholischen Hochschule Mainz gemeinsam durchgef{\"u}hrt wird, setzt damit am Ziel 3 Gesundheit und Wohlergehen der UN-Nachhaltigkeitsziele an. Unter Einbezug der Zielgruppe wurde eine App entwickelt, mit deren Unterst{\"u}tzung {\"a}ltere Ehrenamtliche mit Bewohner*innen in Senioreneinrichtungen biographisch-orientierte Gespr{\"a}che f{\"u}hren k{\"o}nnen. Die Maßnahme wurde im Einzel- und Gruppensetting erfolgreich erprobt. Durch das Erz{\"a}hlen {\"u}ber sich selbst im Austausch mit anderen werden Erinnerungs- und Identit{\"a}tsprozesse aktiviert, und ein positives Selbstbild wird gef{\"o}rdert, was sich nachweislich auf die Lebensqualit{\"a}t auswirkt.}, subject = {Nachhaltigkeit}, language = {de} } @article{MaurerSaiboldGerletal., author = {Maurer, Julia and Saibold, Anna and Gerl, Katharina and Koller, Michael and K{\"o}lbl, Oliver and Pukrop, Tobias and Windschuettl, Sandra and Einhell, Sabine and Herrmann-Johns, Anne and Raptis, Georgios and Mueller, Karolina}, title = {Systematic development of a patient-reported ONCOlogical-ROUTinE-Screening (ONCO-ROUTES) procedure at the University Cancer Center Regensburg}, series = {Journal of Cancer Research and Clinical Oncology}, volume = {150}, journal = {Journal of Cancer Research and Clinical Oncology}, number = {9}, publisher = {Springer Science and Business Media LLC}, issn = {1432-1335}, doi = {10.1007/s00432-024-05955-4}, abstract = {Purpose The evaluation of treatment success and progression in oncology patient-reported outcomes (PROs) is playing an increasingly important role. Meanwhile, PROs are a component of the certification requirements of the German Cancer Society for oncology centers. PROs are used to provide supportive therapy. There is currently no instrument that fully covers the requirements. At the University Hospital Regensburg (UKR), a digital ONCOlogical-ROUTinE-Screening (ONCO-ROUTES) procedure was developed in order to assess the need for supportive therapy in a standardized way and to provide patients with supportive interventions tailored to their needs. Methods On the basis of current requirements and guidelines, the development of ONCO-ROUTES was supported by experts in focus groups and interviews, and digitalization was carried out in connection with the IT infrastructure. Results A Needs-based, Quality-of-life (QoL) and Symptoms Screening (NQS2) tool already established in the routine at the UKR was further developed into ONCO-ROUTES, which is made up of the domains therapy phase, nutrition, tobacco use, alcohol use, quality of life, general condition/functional status, physical activity, psychooncology, social services, and further support needs. By linking the digitized questionnaire to the hospital information system, the results are available for immediate use in routine operations and thus for the referral of patients for further supportive therapy. Conclusion The digital PRO application ONCO-ROUTES is designed to involve patients in monitoring additional supportive needs and thus, improves supportive interdisciplinary treatment.}, language = {en} } @incollection{KoenigGuertlerTlukova, author = {Koenig, Eric and Guertler, Katherine and Tlukov{\´a}, Jolana}, title = {Harnessing learners' domain expertise for LSP curriculum development: Experience-based best practices and strategies}, series = {New to the LSP Classroom? A Selection of Monographs on Successful Practices}, booktitle = {New to the LSP Classroom? A Selection of Monographs on Successful Practices}, editor = {Vranova, Martina}, publisher = {Vernon Press}, address = {Wilmington, DE}, isbn = {978-1-64889-150-2}, pages = {131 -- 146}, abstract = {In Chapter 7, a team of authors from European technical universities addresses the most common challenge novice LSP practitioners usually have—inadequate knowledge of the target domain. They propose strategies to develop the language instructor's technical terminology and concepts. Struggling with feelings of intimidation in an alienating environment of the technical English classroom led the authors to a realization that the best source of target-domain knowledge is their own students. Interacting with students and receiving and appreciating subject-matter input from them bridges the gap between LSP practitioners with humanistic training and their technology-oriented students. By creating the classroom culture of two sets of experts in cooperation to solve a problem, both the teachers and the students can symbiotically learn from each other. Such teacher-student cooperation will give novice LSP practitioners a considerable head start. Moreover, it ensures that course design and curriculum can be tailored to the students' needs. Such student-guided input will also make up for the intensely felt lack of contact between LSP instructors and experts teaching subject-matter courses. The reflections on the unenviable situation of LSP instructors in an environment where everybody else but them has the target-domain knowledge is then followed by a list of specific in-class and take-home activities that incorporate the student-domain expertise in the ESP classroom. All these activities can be adapted to any language, level of proficiency, or target domain.}, language = {en} } @incollection{KurfessAmmerGroetzbach, author = {Kurfeß, Christina and Ammer, Franziska and Gr{\"o}tzbach, Holger}, title = {Rehabilitation von Personen mit einer Aphasie und Dysarthrie}, series = {NeuroRehabilitation : Ein Praxisbuch f{\"u}r interdisziplin{\"a}re Teams}, booktitle = {NeuroRehabilitation : Ein Praxisbuch f{\"u}r interdisziplin{\"a}re Teams}, editor = {Frommelt, Peter and Th{\"o}ne-Otto, Angelika and Gr{\"o}tzbach, Holger}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-662-66956-3}, doi = {10.1007/978-3-662-66957-0_14}, pages = {223 -- 245}, abstract = {Erworbene Sprach- oder Sprechst{\"o}rungen haben nicht nur Konsequenzen f{\"u}r die Patient*innen wegen ihrer beeintr{\"a}chtigten Sprach- oder Sprechleistungen, sondern wirken sich auch auf ihr gesamtes soziales Umfeld aus. Denn Kommunikationsschwierigkeiten f{\"u}hren oft zu Ver{\"a}nderungen der Selbstidentit{\"a}t und der Beziehungen der Betroffenen. Es kann zu Resignation, Frustration, Vermeidungsverhalten gegen{\"u}ber kommunikativen Situationen und sozialem R{\"u}ckzug kommen. Aphasien und Dysarthrien betreffen damit in der sozialen Teilhabe Unterhaltungen im Familien- und Freundeskreis, am Arbeitsplatz oder in der {\"O}ffentlichkeit. Um die Ver{\"a}nderungen erfassen zu k{\"o}nnen, werden ein personzentriertes Verst{\"a}ndnis der Sprech- und Sprachst{\"o}rungen sowie eine genaue Erfassung der Symptomatik und der daraus resultierenden Einschr{\"a}nkungen ben{\"o}tigt. Dazu steht eine Reihe von Testverfahren zur Verf{\"u}gung, die verschiedene Parameter erfassen. Die personzentrierte Therapie bezieht sich gleichermaßen auf K{\"o}rperfunktion, Aktivit{\"a}ten und Teilhabe sowie auf Umweltfaktoren. Neben der Aufgabe, die Erwartungen, Hoffnungen und W{\"u}nsche der Patient*innen wahrzunehmen und zu verstehen, gilt es, Therapieans{\"a}tze der jeweils bestehenden Symptomatik und den Zielen anzupassen und - auch im Zuge der zunehmenden Forderung nach evidenzbasierten Behandlungsmethoden - kritisch zu hinterfragen.}, language = {de} } @article{AngererHaberkernLauer, author = {Angerer, Linda and Haberkern, Annika and Lauer, Norina}, title = {Mundmotorische {\"U}bungen in der Artikulationstherapie?}, series = {Forum Logop{\"a}die}, volume = {39}, journal = {Forum Logop{\"a}die}, number = {2}, pages = {20 -- 26}, abstract = {Der Artikel pr{\"a}sentiert die Ergebnisse einer deutschlandweiten quantitativen Online-Befragung von Therapeut*innen der Logop{\"a}die/Sprachtherapie zur Nutzung mundmotorischer {\"U}bungen (M{\"U}) in der Artikulationstherapie bei Kindern. Demnach setzen 70 Prozent der 239 Befragten M{\"U} in der Therapie phonetischer St{\"o}rungen ein und kennen M{\"U} aus ihrer Ausbildung, aus der Fachliteratur sowie aus Fortbildungen. Die am h{\"a}ufigsten ausgew{\"a}hlten Gr{\"u}nde f{\"u}r den Einsatz waren die Empfehlung der (fr{\"u}heren) Ausbildungseinrichtung, die eigene Berufserfahrung und Erkenntnisse der besuchten Fortbildungen. M{\"U} werden eingesetzt, weil sie im Rahmen von Fortbildungen, in Ratgebern und Lehrb{\"u}chern empfohlen werden. Dies widerspricht jedoch der Studienlage, welche die Wirksamkeit von M{\"U} zur Intervention bei phonetischen St{\"o}rungen widerlegt. Die Erhebung zeigt, dass viele Therapeut*innen M{\"U} dennoch weiterhin verwenden. Der Artikel pl{\"a}diert f{\"u}r ein effektives und effizientes Arbeiten auf der Grundlage evidenzbasierter Methoden auch in der Artikulationstherapie.}, subject = {Artikulation}, language = {de} } @article{KurfessCorstenNickeletal., author = {Kurfess, Christina and Corsten, Sabine and Nickel, Maren and Kreiter, Daniel and Lauer, Norina}, title = {Improving health-related quality of life for people with aphasia through peer support using the digital network PeerPAL}, series = {Aphasiology}, journal = {Aphasiology}, publisher = {Taylor \& Francis}, doi = {10.1080/02687038.2025.2505641}, pages = {1 -- 24}, abstract = {Background: Aphasia is often associated with psychosocial changes that may affect health-related quality of life, risk of depression or social participation. One possible intervention to address these psychosocial changes is peer contact. However, this often requires professional support (e.g. supervised support groups), whereas a digital option may allow for autonomous, asynchronous peer contact. Therefore, we developed an app adapted to the specific needs of people with aphasia to stimulate digital and analogue interactions. Aims: The aim of the study was to evaluate a tailored app for people with aphasia that can be used to establish peer contact and enable digital and analogue interactions. The impact of using the app on health-related quality of life, social participation and depression prevention was analysed. Methods \& Procedures: The study design was a pre-post wait-list-controlled comparison in which half of the participants (n = 18) waited three months before starting the intervention, and the other half of the participants (n = 18) started the intervention immediately. During the intervention, the app was used by all participants (n = 36) for three months after a training session, followed by three months of optional app use until follow-up. Health-related quality of life (SAQOL39g, GHQ-12), communicative participation (CPIB), social support (F-SozU), depression markers (GDS, DISCs), and activity in the app were recorded at each time point. Analyses were mainly non-parametric to calculate changes during the intervention and to compare the intervention with the waiting period. The study is registered in the German Register of Clinical Trials (DRKS00023855). Outcomes \& Results: SAQOL-39g data improved significantly for the whole group during the intervention period (z = -3.043, p = 0.002, r = -0.598), but not during the waiting period (z = 0.402, p = 0.705). Scores remained stable until follow-up, and there was no worsening of depression markers over the entire period. No linear correlation was found between the improvement in SAQOL-39g and activity in the app (p = 0.329, r = 0.167). Conclusions: People with aphasia were able to use the app and showed an intervention-specific effect on health-related quality of life. The amount of activity in the app seems to be less critical for changes. Other factors, such as feeling connected to peers, appear to be relevant. Future studies should explore who might benefit most from the app.}, subject = {Aphasie}, language = {en} } @article{DendorferMaierHammer, author = {Dendorfer, Sebastian and Maier, Hans J{\"u}rgen and Hammer, Joachim}, title = {Fatigue damage in cancellous bone: an experimental approach from continuum to micro scale}, series = {Journal of the Mechanical Behavior of Biomedical Materials}, volume = {2}, journal = {Journal of the Mechanical Behavior of Biomedical Materials}, number = {1}, doi = {10.1016/j.jmbbm.2008.03.003}, pages = {113 -- 119}, abstract = {Repeated loadings may cause fatigue fractures in bony structures. Even if these failure types are known, data for trabecular bone exposed to cyclic loading are still insufficient as the majority of fatigue analyses on bone concentrate on cortical structures. Despite its highly anisotropic and inhomogeneous structure, trabecular bone is treated with continuum approaches in fatigue analyses. The underlying deformation and damage mechanism within trabecular specimens are not yet sufficiently investigated. In the present study different types of trabecular bone were loaded in monotonic and cyclic compression. In addition to the measurement of integral specimen deformations, optical deformation analysis was employed in order to obtain strain distributions at different scale levels, from the specimens' surface to the trabeculae level. These measurements allowed for the possibility of linking the macroscopic and microscopic mechanical behaviour of cancellous bone. Deformations were found to be highly inhomogeneous across the specimen. Furthermore strains were found to already localise at very low load levels and after few load cycles. Microcracks in individual trabeculae were induced in the very early stage of cyclic testing. The results provide evidence of the capability of the method to supply essential data on the failure behaviour of individual trabeculae in future studies.}, subject = {Knochen}, language = {en} } @incollection{DendorferMaierHammer, author = {Dendorfer, Sebastian and Maier, Hans J{\"u}rgen and Hammer, Joachim}, title = {How do age and anisotropy affect the fatigue behaviour of cancellous bone?}, series = {Medicine Meets Engineering}, booktitle = {Medicine Meets Engineering}, publisher = {IOS Press}, pages = {68 -- 74}, abstract = {The fatigue behaviour of materials is of particular interest for the failure prediction of materials and structures exposed to cyclic loading. For trabecular bone structures only a few sets of lifetime data have been reported in the literature and structural measures are commonly not considered. The influence of load contributions not aligned with the main physiological axis remains unclear. Furthermore age effects on the fatigue behaviour are not well described. In the present study, different groups of human vertebral cancellous bone were exposed to cyclic compression. The inital modulus and therefore lifetimes were found to be highly dependent on age. The decrease in both with increasing age was much more pronounced in specimens which were not aligned with the main physiological axis. This implies that old bone is much more sensitive to (cyclic) failure loads in general but particularly to loads which are not coincident with the physiological main axis.}, subject = {Knochenbruch}, language = {en} } @incollection{PfingstenSchedelMichel, author = {Pfingsten, Andrea and Schedel, Valentin and Michel, Natalie}, title = {Physiotherapeutische Tele-Intervention - Machbarkeit und funktionelle Ver{\"a}nderungen bei Schlaganfallbetroffenen}, series = {Digitale Technik f{\"u}r ambulante Pflege und Therapie III}, booktitle = {Digitale Technik f{\"u}r ambulante Pflege und Therapie III}, editor = {Weber, Karsten and Haug, Sonja and Lauer, Norina and Mohr, Christa and Pfingsten, Andrea and Raptis, Georgios and Bahr, Gudrun}, publisher = {transcript}, address = {Bielefeld}, isbn = {978-3-8394-6728-2}, doi = {10.14361/9783839467282-007}, pages = {125}, abstract = {Dieser Artikel untersucht die Machbarkeit und Wirksamkeit einer physiotherapeutischen Tele-Intervention bei Schlaganfallpatient*innen. Die prospektive, nicht kontrollierte Interventionsstudie basiert auf einem Mixed-Methods-Design und analysiert funktionelle Ver{\"a}nderungen sowie die Lebensqualit{\"a}t der Teilnehmenden vor und nach der Intervention. Eingeschlossen wurden postakute und chronische Schlaganfallpatient*innen mit stabilen Krankheitsbildern, die in ihrem h{\"a}uslichen Umfeld lebten. Die Intervention bestand aus videobasierten Einzelsitzungen und einer optionalen Gruppenintervention, die Physiotherapie und Logop{\"a}die kombinierte. Die Ergebnisse zeigten signifikante Verbesserungen in der Arm-Hand-Funktion und der Teilhabef{\"a}higkeit. Die Teletherapie erwies sich als eine praktikable Erg{\"a}nzung zur traditionellen Rehabilitation, insbesondere in l{\"a}ndlichen Regionen, und f{\"o}rderte die Autonomie und das aktive Engagement der Patient*innen in ihrem Genesungsprozess. Die Studie belegt das Potenzial teletherapeutischer Maßnahmen zur {\"U}berbr{\"u}ckung von Versorgungsl{\"u}cken und zur Sicherstellung einer kontinuierlichen, hochfrequenten Rehabilitation.}, subject = {Schlaganfall}, language = {de} } @inproceedings{GreinerCurrleEttletal., author = {Greiner, Nina and Currle, Edda and Ettl, Katrin and Frommeld, Debora and Haug, Sonja and Kudienko, Natalie and Lauer, Norina and Lichtenauer, Norbert and Meussling-Sentpali, Annette and Middel, Luise and Mohr, Christa and Pfingsten, Andrea and Popp, Christof and Raptis, Georgios and Weber, Karsten}, title = {Technik im Alltag - Technik zum Leben : Telepr{\"a}senzgest{\"u}tzte Pflege und Therapie bei Schlaganfallpatient*innen}, series = {Kann Digital Pflege?: Clusterkonferenz ,,Zukunft der Pflege", 3., September 2020, N{\"u}rnberg}, volume = {Konferenzband Teil 1}, booktitle = {Kann Digital Pflege?: Clusterkonferenz ,,Zukunft der Pflege", 3., September 2020, N{\"u}rnberg}, address = {K{\"o}nigstetten, {\"O}sterreich}, issn = {2710-3048}, pages = {57 -- 61}, abstract = {Vorgestellt wird das Forschungsvorhaben des interdisziplin{\"a}ren Forschungsprojekts „DeinHaus 4.0 - Telepr{\"a}senzroboter f{\"u}r die Pflege und Unterst{\"u}tzung von Schlaganfallpatientinnen und -patienten (TePUS)". {\"U}ber geeignete Robotersysteme sollen den Proband*innen individuell abgestimmte Angebote aus den Bereichen Telenursing und Teletherapie zur Verf{\"u}gung gestellt werden. Hierbei werden einerseits Telepr{\"a}senzsitzungen durchgef{\"u}hrt, anderseits kommen verschiedene Apps zum Einsatz. Die Interventionen werden mittels eines Mixed-Methods-Ansatzes evaluiert. Begleitend werden Technikakzeptanz und Nutzungsbereitschaft untersucht.}, subject = {Schlaganfall}, language = {de} } @incollection{KoenigGuertler, author = {Koenig, Eric and Guertler, Katherine}, title = {Supporting weaker students in the mixed-level ESL classroom}, series = {English Language Teaching Through the Lens of Experience}, booktitle = {English Language Teaching Through the Lens of Experience}, editor = {Haase, Christoph}, publisher = {Cambridge Scholars Publisher}, address = {Newcastle-upon-Tyne}, isbn = {978-1-5275-3718-7}, pages = {181 -- 194}, language = {en} } @article{GiordanoLauerLeuschetal., author = {Giordano, Katharina and Lauer, Norina and Leusch, Vera and Danner, C{\"a}cilia and Kreiter, Daniel and Corsten, Sabine}, title = {Pr{\"a}ventionsforschung mit Menschen im Alter}, series = {Forum Logop{\"a}die}, volume = {37}, journal = {Forum Logop{\"a}die}, number = {7}, doi = {10.2443/skv-s-2023-53020230104}, pages = {26 -- 31}, abstract = {Mit dem demografischen Wandel wird der Anteil der institutionalisierten Menschen im hohen Alter in den kommenden Jahrzehnten stark zunehmen. Sie sind oftmals betroffen von altersbedingten Einschr{\"a}nkungen in der Kommunikation, dem Erleben von Einsamkeit, Einbußen in der Lebensqualit{\"a}t und tragen ein erh{\"o}htes Risiko, an einer Demenz zu erkranken. Mit Blick auf die m{\"o}gliche Entwicklung logop{\"a}disch relevanter Beeintr{\"a}chtigungen erscheint es sinnvoll, entsprechende Pr{\"a}ventionsmaßnahmen zu erarbeiten. Die Rekrutierung und Einbindung der Zielgruppe gestaltet sich durch ihre institutionelle Einbettung und besonderen Bedarfe komplex. Barrieren und potenzielle F{\"o}rderfaktoren f{\"u}r die Forschung mit Bewohner*innen von Senioreneinrichtungen werden anhand der aktuellen Literatur und der Erfahrungen aus dem Forschungsprojekt BaSeTaLK vorgestellt. Es werden erste Ideen generiert, wie sich die genannten Herausforderungen durch die Einbindung von Logop{\"a}d*innen an der Schnittstelle von Forschung und Praxis {\"u}berwinden lassen und welche besondere Rolle auch Studierende der Logop{\"a}die in der geriatrischen Forschung einnehmen k{\"o}nnen. Außerdem wird der Mehrwert f{\"u}r die klinisch-praktische Versorgung diskutiert.}, subject = {Pr{\"a}vention}, language = {de} } @article{KurfessLauerKnieriemenetal., author = {Kurfeß, Christina and Lauer, Norina and Knieriemen, Marie and Kreiter, Daniel and Corsten, Sabine}, title = {Gut vernetzt ist halb befreundet!?}, series = {Forum Logop{\"a}die}, volume = {36}, journal = {Forum Logop{\"a}die}, number = {3}, publisher = {Schulz-Kirchner-Verlag}, pages = {6 -- 11}, abstract = {Die Entwicklung einer an die spezifischen Bed{\"u}rfnisse von Menschen mit Aphasie angepassten Smartphone-basierten App erfordert einen umfangreichen Entwicklungsprozess. Dabei ist es wichtig, die Zielgruppe von Anfang an in den Prozess einzubeziehen, um die spezifischen W{\"u}nsche und Anforderungen an die App erfassen und in den Entwicklungsprozess integrieren zu k{\"o}nnen. In diesem Beitrag wird die nutzerzentrierte, partizipative Entwicklung der App PeerPAL vorgestellt. Mit der App sollen neben einem digitalen Austausch auch reale Face-to-Face-Treffen stimuliert werden mit dem Ziel, die autonome Vernetzung unter den Betroffenen zu f{\"o}rdern und dadurch die Lebensqualit{\"a}t von Menschen mit Aphasie zu steigern.}, subject = {Aphasie}, language = {de} } @article{KnieriemenLauerGiordanoetal., author = {Knieriemen, Marie and Lauer, Norina and Giordano, Katharina and Kreiter, Daniel and Corsten, Sabine}, title = {In den Austausch kommen}, series = {Pflegezeitschrift}, volume = {75}, journal = {Pflegezeitschrift}, number = {10}, publisher = {Springer Nature}, doi = {10.1007/s41906-022-1922-4}, pages = {58 -- 63}, abstract = {Mit der BaSeTaLK-App wird eine Tablet-gest{\"u}tzte Biographiearbeit f{\"u}r institutionalisierte {\"a}ltere Menschen zur Steigerung der Lebensqualit{\"a}t erm{\"o}glicht. Um Gelingensbedingungen f{\"u}r die Erprobung und die m{\"o}gliche Implementierung der Maßnahme zu bestimmen, wurde die Perspektive von Mitarbeitenden einer Pflegeeinrichtung eingeholt. Insbesondere eine umfassende Informationsvermittlung und eine flexible, enge Zusammenarbeit mit den Forschenden wurden hervorgehoben.}, subject = {Biografieforschung}, language = {de} } @article{HoelscherWeberLazarevetal., author = {H{\"o}lscher, Thomas and Weber, Tim A. and Lazarev, Igor A. and Englert, Carsten and Dendorfer, Sebastian}, title = {The influence of rotator cuff tears on glenohumeral stability during abduction tasks}, series = {Journal of Orthopaedic Research}, volume = {34}, journal = {Journal of Orthopaedic Research}, number = {9}, doi = {10.1002/jor.23161}, pages = {1628 -- 1635}, abstract = {One of the main goals in reconstructing rotator cuff tears is the restoration of glenohumeral joint stability, which is subsequently of utmost importance in order to prevent degenerative damage such as superior labral anterior posterior (SLAP) lesion, arthrosis, and malfunction. The goal of the current study was to facilitate musculoskeletal models in order to estimate glenohumeral instability introduced by muscle weakness due to cuff lesions. Inverse dynamics simulations were used to compute joint reaction forces for several static abduction tasks with different muscle weakness. Results were compared with the existing literature in order to ensure the model validity. Further arm positions taken from activities of daily living, requiring the rotator cuff muscles were modeled and their contribution to joint kinetics computed. Weakness of the superior rotator cuff muscles (supraspinatus; infraspinatus) leads to a deviation of the joint reaction force to the cranial dorsal rim of the glenoid. Massive rotator cuff defects showed higher potential for glenohumeral instability in contrast to single muscle ruptures. The teres minor muscle seems to substitute lost joint torque during several simulated muscle tears to maintain joint stability. Joint instability increases with cuff tear size. Weakness of the upper part of the rotator cuff leads to a joint reaction force closer to the upper glenoid rim. This indicates the comorbidity of cuff tears with SLAP lesions. The teres minor is crucial for maintaining joint stability in case of massive cuff defects and should be uprated in clinical decision-making.}, subject = {Rotatorenmanschettenriss}, language = {en} } @article{LindertWehrweinKlempereretal., author = {Lindert, Jutta and Wehrwein, Annette and Klemperer, David and Walter, U.}, title = {Public health education in health-related study programs in Germany: Perspectives from course coordinators}, series = {Gesundheitswesen}, volume = {81}, journal = {Gesundheitswesen}, publisher = {Thieme}, doi = {10.1055/s-0043-116940}, pages = {599 -- 605}, abstract = {Hintergrund Inhalte von Public Health werden in Deutschland in gesundheitsbezogenen Studieng{\"a}ngen an Hochschulen und Universit{\"a}ten gelehrt. Ziel dieser Studie war es, Daten zur Lehre und zur Kooperation von Lehrenden von Public Health in gesundheitsbezogenen Studieng{\"a}ngen in Deutschland zur Verf{\"u}gung zu stellen. Methode Eine Querschnittsuntersuchung wurde online-basiert vom 01.06. bis 15.09.2015 an 93 Hochschulen/Universit{\"a}ten in Deutschland mit 351 Studiengangsverantwortlichen aus gesundheitsbezogenen Studieng{\"a}ngen durchgef{\"u}hrt. Einbezogen wurden Public Health Studieng{\"a}nge und gesundheitsbezogene Studieng{\"a}nge, deren Hochschulen bzw. Universit{\"a}ten entweder Mitglied in der "Deutschen Gesellschaft f{\"u}r Sozialmedizin und Pr{\"a}vention" (DGSMP) oder in der Gesellschaft "Hochschulen f{\"u}r Gesundheit" (HOGE) sind. Teilgenommen an dieser Studie haben N=104 Studiengangsverantwortliche (43\% M{\"a}nner, 57\% Frauen). In Public Health Studieng{\"a}ngen wurden „Global Health" und "Umwelt und Gesundheit" als Studieninhalte h{\"a}ufiger als in gesundheitsbezogenen Studieng{\"a}ngen benannt; in gesundheitsbezogenen Studieng{\"a}ngen wurden h{\"a}ufiger "Ethik" und "Gesundheitspsychologie" als Lehrinhalte benannt. Finanzielle Unterst{\"u}tzungen durch die Hochschulen/ Universit{\"a}ten sowie strukturierte Partnerschaften zwischen Hochschulen und/ oder Universit{\"a}ten werden von Lehrenden an Hochschulen (36\%) und an Universit{\"a}ten (40\%) gew{\"u}nscht. Lehrende an Hochschulen w{\"u}nschen dar{\"u}ber hinaus Promotionspartnerschaften. Schlussfolgerung Bisher gibt es in Deutschland keine einheitlichen fachlichen Qualit{\"a}tskriterien f{\"u}r Absolvierende von Public Health bzw. gesundheitsbezogenen Studieng{\"a}ngen. Zudem gibt es nach Aussage der Studiengangsverantwortlichen dieser Studieng{\"a}nge wenig Kooperation zwischen Lehrenden der Public Health bzw. der gesundheitsbezogenen Studieng{\"a}nge.}, language = {en} } @article{WagnerKranzKrenkeletal., author = {Wagner, Maria Stella and Kranz, Michael and Krenkel, Lars and Pointner, Daniel and Foltan, Maik and Lubnow, Matthias and Lehle, Karla}, title = {Computer based visualization of clot structures in extracorporeal membrane oxygenation and histological clot investigations for understanding thrombosis in membrane lungs}, series = {Frontiers in Medicine}, journal = {Frontiers in Medicine}, number = {11}, editor = {Becatti, Matteo}, publisher = {Frontiers}, doi = {10.3389/fmed.2024.1416319}, abstract = {Extracorporeal membrane oxygenation (ECMO) was established as a treatment for severe cardiac or respiratory disease. Intra-device clot formation is a common risk. This is based on complex coagulation phenomena which are not yet sufficiently understood. The objective was the development and validation of a methodology to capture the key properties of clots deposed in membrane lungs (MLs), such as clot size, distribution, burden, and composition. One end-oftherapy PLS ML was examined. Clot detection was performed using multidetector computed tomography (MDCT), microcomputed tomography (μCT), and photography of fiber mats (fiber mat imaging, FMI). Histological staining was conducted for von Willebrand factor (vWF), platelets (CD42b, CD62P), fibrin, and nucleated cells (4′, 6-diamidino-2-phenylindole, DAPI). The three imaging methods showed similar clot distribution inside the ML. Independent of the imaging method, clot loading was detected predominantly in the inlet chamber of the ML. The μCT had the highest accuracy. However, it was more expensive and time consuming than MDCT or FMI. The MDCT detected the clots with low scanning time. Due to its lower resolution, it only showed clotted areas but not the exact shape of clot structures. FMI represented the simplest variant, requiring little effort and resources. FMI allowed clot localization and calculation of clot volume. Histological evaluation indicated omnipresent immunological deposits throughout the ML. Visually clot-free areas were covered with leukocytes and platelets forming platelet-leukocyte aggregates (PLAs). Cells were embedded in vWF cobwebs, while vWF fibers were negligible. In conclusion, the presented methodology allowed adequate clot identification and histological classification of possible thrombosis markers such as PLAs.}, language = {en} } @article{LingelHausPaschkeetal., author = {Lingel, Maximilian P. and Haus, Moritz and Paschke, Lukas and Foltan, Maik and Lubnow, Matthias and Gruber, Michael and Krenkel, Lars and Lehle, Karla}, title = {Clinical relevance of cell-free DNA during venovenous extracorporeal membrane oxygenation}, series = {Artificial organs}, volume = {47}, journal = {Artificial organs}, number = {11}, publisher = {Wiley}, issn = {1525-1594}, doi = {10.1111/aor.14616}, pages = {1720 -- 1731}, abstract = {BACKGROUND: Thrombosis remains a critical complication during venovenous extracorporeal membrane oxygenation (VV ECMO). The involvement of neutrophil extracellular traps (NETs) in thrombogenesis has to be discussed. The aim was to verify NETs in the form of cell-free DNA (cfDNA) in the plasma of patients during ECMO. METHODS: A fluorescent DNA-binding dye (QuantifFluor®, Promega) was used to detect cell-free DNA in plasma samples. cfDNA concentrations from volunteers (n = 21) and patients (n = 9) were compared and correlated with clinical/technical data before/during support, ECMO end and time of a system exchange. RESULTS: Before ECMO, patients with a median (IQR) age of 59 (51/63) years, SOFA score of 11 (10/15), and ECMO run time of 9.0 (7.0/19.5) days presented significantly higher levels of cfDNA compared to volunteers (6.4 (5.8/7.9) ng/μL vs. 5.9 (5.4/6.3) ng/μL; p = 0.044). Within 2 days after ECMO start, cfDNA, inflammatory, and hemolysis parameters remained unchanged, while platelets decreased (p = 0.005). After ECMO removal at the end of therapy, cfDNA, inflammation, and coagulation data (except antithrombin III) remained unchanged. The renewal of a system resulted in known alterations in fibrinogen, d-dimers, and platelets, while cfDNA remained unchanged. CONCLUSION: Detection of cfDNA in plasma of ECMO patients was not an indicator of acute and circuit-induced thrombogenesis.}, language = {en} } @article{FoltanDinhGruberetal., author = {Foltan, Maik and Dinh, D. and Gruber, Michael and M{\"u}ller, Thomas and Hart, C. and Krenkel, Lars and Schmid, C. and Lehle, Karla}, title = {Incidence of neutrophil extracellular traps (NETs) in different membrane oxygenators: pilot in vitro experiments in commercially available coated membranes}, series = {Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs}, journal = {Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs}, doi = {10.1007/s10047-024-01486-4}, abstract = {Neutrophil extracellular traps (NETs) were detected in blood samples and in cellular deposits of oxygenator membranes during extracorporeal membrane oxygenation (ECMO) therapy and may be responsible for thrombogenesis. The aim was to evaluate the effect of the base material of gas fiber (GF, polymethylpentene) and heat exchange (HE) membranes and different antithrombogenic coatings on isolated granulocytes from healthy volunteers under static culture conditions. Contact of granulocytes with membranes from different ECMO oxygenators (with different surface coatings) and uncoated-GFs allowed detection of adherent cells and NETotic nuclear structures (normal, swollen, ruptured) using nuclear staining. Flow cytometry was used to identify cell activation (CD11b/CD62L, oxidative burst) of non-adherent cells. Uncoated-GFs were used as a reference. Within 3 h, granulocytes adhered to the same extent on all surfaces. In contrast, the ratio of normal to NETotic cells was significantly higher for uncoated-GFs (56-83\%) compared to all coated GFs (34-72\%) (p < 0.001) with no difference between the coatings. After material contact, non-adherent cells remained vital with unchanged oxidative burst function and the proportion of activated cells remained low. The expression of activation markers was independent of the origin of the GF material. In conclusion, the polymethylpentene surfaces of the GFs already induce NET formation. Antithrombogenic coatings can already reduce the proportion of NETotic nuclei. However, it cannot be ruled out that NET formation can induce thrombotic events. Therefore, new surfaces or coatings are required for future ECMO systems and long-term implantable artificial lungs.}, language = {en} } @article{KurfessCorstenNickeletal., author = {Kurfess, Christina and Corsten, Sabine and Nickel, Maren and Knieriemen, Marie and Kreiter, Daniel and Lauer, Norina}, title = {Peer-to-peer support: digital networking in aphasia to improve quality of life (PeerPAL)}, series = {Frontiers in Communication}, volume = {8}, journal = {Frontiers in Communication}, publisher = {Frontiers Media S.A.}, doi = {10.3389/fcomm.2023.1187233}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-64881}, abstract = {Background: People with aphasia (PWA) often suffer from reduced participation and quality of life. Nevertheless, there are currently only a few specific interventions that respond to this problem. Participation and quality of life could be increased by interacting with peers who have similar experiences. Digital social networks could stimulate an autonomous interaction. However, digital social networks need to be adapted to the specific needs of PWA. Therefore, a participatory, agile process involving the target group should be chosen to develop such a olution, i.e., an app. The research project consists of a total of three phases. In the first phase—app development—the app was developed and programmed including the target group. In the second phase—app testing—the usability and user-friendliness of the app were evaluated with four PWA. In the third phase—feasibility and preliminary effcacy—that will be described in the article, the impact of the app on PWA will be evaluated. Aims: The overarching aim of our study is to provide preliminary effcacy of the intervention. Digital social interaction with other PWA can lead to increased social integration. In addition to digital interaction, personal encounters between PWA should be encouraged. As a result, we expect an improvement in quality of life of PWA. Additionally, we focus on identification of the most appropriate measurements to discover changes associated with the intervention. Methods: The evaluation, which is described in this paper, takes place in a pre-test - post-test design with a total of n = 48 PWA. Participants will be recruited in regional clusters to facilitate face-to-face meetings. Half of the participants will be assigned to the delayed intervention group and the other half to the immediate intervention group. Participants in the delayed intervention group will go through a 3-month waiting period before using the app, while the participants of the immediate intervention group will start using the app for 3 months right away. Inclusion criteria are the presence of chronic aphasia (at least 6 months) and possession of a smartphone with internet access. Questionnaires on quality of life (SAQOL-39, GHQ-12), depression (GDS, DISCs), communicative participation (CPIB), and social support (F-SozU) will be conducted at inclusion (t0), after 3 months of app use (t1), and after another 3 months for follow-up (t2). Participants in the delayed intervention group will be assessed twice before the intervention, before the 3-month waiting period (t0a) and after the waiting period (t0b). In addition to the quantitative measures, interviews will take place with 6 to 8 selected participants after 3 months of app use. Responses will be analysed using Thematic Analysis. Discussion: The app will be the first social network tool that is systematically developed with PWA. Initial indications from the first phases are that the app can be used by PWA, so that the evaluation of this app version can take place in the third phase. Results of this study can provide an initial indication of whether social network support is a suitable intervention. Findings will help provide information on the feasibility of digital connectivity for PWA. Preliminary findings on its impact on the participation and quality of life of PWA could be made available.}, subject = {Aphasie}, language = {en} } @misc{Marterer, type = {Master Thesis}, author = {Marterer, Verena}, title = {A Characterisation of Motives and Barriers to Taking up Academic Study in the Field of Electrical Engineering}, address = {Regensburg}, doi = {10.35096/othr/pub-6255}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-62550}, school = {Ostbayerische Technische Hochschule Regensburg}, pages = {159}, abstract = {The problem description comes to the fore when the wide-ranging subject area of electrical engineering is combined and analyzed with different types of schools. It is becoming increasingly rare for elementary school children to come to grips with technology in the sense of recognizing functional interrelationships and understanding modes of action in the context of technical-practical confrontation. The picture at secondary schools is also rather sobering. Here, a strong focus on facts and knowledge and too little emphasis on modeling, application and problem solving lead to insufficient results in the cognitive area. In addition, a massive shortage of engineers and specialists with a technical and scientific orientation has been predicted for years and is being increasingly observed. The motivation of students in traditional lectures is decreasing and in general there is a decline of university students in technical subjects. These problems are not only known throughout Germany, but also internationally. Especially in developing countries, additional problems make technical education more difficult, regardless of the type of school. Therefore, this master thesis is evaluated in South Africa in order to consider as many influencing factors as possible. "Learning is experience. Everything else is simply information." - Methods and concepts developed in the thesis build upon this quote of Albert Einstein. Teaching methods are elaborated and applied for three different age groups and school types, depending on known influencing factors. The aim of this thesis is not to produce further findings in the sense of basic research, but to show ways in which the current situation can be steered in a different direction. It has been shown that technology lessons in elementary/secondary schools inspire interest in technical professions in the field of electrical engineering. Furthermore, the combination of frontal teaching, for a necessary theoretical background, together with student-active, action-oriented teaching shows advantages in terms of learning efficiency and an increase in performance levels for all three age groups. However, it could also be observed that factors such as social background, family influence and gender have partial effects on the promotion and education in the field of electrical engineering.}, language = {en} } @article{PaschkeFoltanWagneretal., author = {Paschke, Lukas and Foltan, Maik and Wagner, Maria S. and Lubnow, Matthias and Gruber, Michael and Krenkel, Lars and Lehle, Karla}, title = {Clinical Relevance of Platelet-Leukocyte Aggregates and Platelet P-Selectin Expression During Venovenous Extracorporeal Membrane Oxygenation}, series = {ASAIO Journal}, journal = {ASAIO Journal}, number = {April 03}, publisher = {Wolters Kluwer}, issn = {1058-2916}, doi = {10.1097/MAT.0000000000002421}, abstract = {Thrombosis continues to be a significant complication during venovenous extracorporeal membrane oxygenation (V-V ECMO). Platelet activation markers might serve as indicators of inflammation and thrombogenesis. The aim was to identify these markers in ECMO patients. Blood from 10 ECMO patients (before, during, after ECMO) and 11 healthy volunteers were collected to determine platelet-neutrophil-aggregates (PNAs), platelet-monocyte-aggregates (PMAs), fibrinogen-binding, and P-selectin-expression on platelets by flow cytometry. Critical illness was associated with significantly elevated levels of PNAs and PMAs, increased P-selectin expression, reduced fibrinogen-binding, and restricted activation of platelets. Although PNAs and PMAs decreased significantly within 2 hours after the initiation of ECMO and remained at those levels, ECMO did not affect basal P-selectin expression and fibrinogen-binding. These results correlated with coagulation activation. Platelet markers before ECMO were not indicators for an imminent system exchange and end of therapy. In conclusion, platelet dysfunction during ECMO was mainly attributed to the critical illness. Extracorporeal membrane oxygenation support strengthened the restricted response of platelets to exogenous agonists (P-selectin). Furthermore, a decrease in PNAs/PMAs after ECMO started identified a reduced inflammatory response. There was no correlation of analyzed platelet parameters with the incidence of thrombotic complications.}, language = {en} } @book{LauerWagnerKubitz, author = {Lauer, Norina and Wagner, Susanne and Kubitz, Katharina}, title = {Auditive Verarbeitungsst{\"o}rungen bei Kindern, Jugendlichen und Erwachsenen : Grundlagen - Klinik - Diagnostik - Therapie}, edition = {5., vollst. {\"u}berarb. u. erweit. Aufl.}, publisher = {Thieme}, address = {Stuttgart}, isbn = {9783132454941}, pages = {208}, abstract = {Das Buch vermittelt fundierte Grundlagen, Diagnostik und Interventionsm{\"o}glichkeiten bei auditiven Verarbeitungsst{\"o}rungen (AVS) im Kindes-, Jugend- und Erwachsenenalter. Auf Basis des Modells der auditiven Verarbeitung und der zugrunde liegenden H{\"o}rverarbeitungsprozesse bietet es einen umfassenden Einblick in das St{\"o}rungsbild AVS und dessen Auswirkungen. Es stellt g{\"a}ngige Diagnostikverfahren vor und diskutiert effektive Maßnahmen zur Beratung, Kompensation und Therapie.}, subject = {Zentrales H{\"o}ren}, language = {de} } @article{SchmidbauerBeckerHaug, author = {Schmidbauer, Simon and Becker, Maria and Haug, Sonja}, title = {Online Political Participation of Refugees in Germany: Analysis of a Survey in Bavaria}, series = {Sage Online}, journal = {Sage Online}, publisher = {Sage}, address = {Thousand Oaks}, doi = {10.1177/21582440241286303}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-77671}, abstract = {New media are an important resource for the political participation of marginalized groups. However, there is still a lack of knowledge about the factors that influence whether this opportunity is used. Influencing factors emerge from both the Civic Voluntarism Model and previous research on migrants' political activity. Using data collected in 2019/2020 from 486 refugees living in Bavaria, we estimate linear probability models to investigate facilitating factors for the use of new media for political participation. The analysis shows that refugees in Germany who inform themselves about politics online tend to be predominantly male, higher educated, and politically involved. Language skills and the duration of stay also appear to be important. For the expression of one's political opinion online, gender and language skills have an impact, but informing oneself about German politics, political interest, and offline political activity in Germany are the most relevant factors. This indicates that there is a close link between on- und offline activity. However, using the internet requires particular resources, so that people with lower language skills, for example, are particularly disadvantaged.}, language = {de} } @inproceedings{SchmidbauerHaug, author = {Schmidbauer, Simon and Haug, Sonja}, title = {Quantitative surveys of refugees}, series = {Polarisierte Welten, 41. Kongress der Deutschen Gesellschaft f{\"u}r Soziologie, 26.-30. Sept. 2022, Bielefeld}, booktitle = {Polarisierte Welten, 41. Kongress der Deutschen Gesellschaft f{\"u}r Soziologie, 26.-30. Sept. 2022, Bielefeld}, editor = {Villa, Paula-Irene}, address = {Bielefeld}, organization = {Deutsche Gesellschaft f{\"u}r Soziologie}, doi = {10.35096/othr/pub-7836}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-78368}, pages = {8}, abstract = {Contribution to the Ad Hoc Group "M{\"o}glichkeiten der quantitativen Erforschung schwer erreichbarer, versteckter und marginalisierter Bev{\"o}lkerungsgruppen"}, subject = {Migration}, language = {en} } @article{HaerterDirmaierScholletal., author = {Haerter, Martin and Dirmaier, J{\"o}rg and Scholl, Isabelle and Donner-Banzhoff, Norbert and Dierks, Marie-Luise and Eich, Wolfgang and M{\"u}ller, Hardy and Klemperer, David and Koch, Klaus and Bieber, Christiane}, title = {The long way of implementing patient-centered care and shared decision making in Germany}, series = {Zeitschrift f{\"u}r Evidenz, Fortbildung und Qualit{\"a}t im Gesundheitswesen}, volume = {123}, journal = {Zeitschrift f{\"u}r Evidenz, Fortbildung und Qualit{\"a}t im Gesundheitswesen}, publisher = {Elsevier}, doi = {10.1016/j.zefq.2017.05.006}, pages = {46 -- 51}, abstract = {The main focus of the paper is on the description of the development and current state of research and implementation of patient-centered care (PCC) and shared decision making (SDM) after fifteen years of substantial advances in health policy and health services research. What is the current state of SDM in health policy? The "Patients' Rights Act" from 2013 standardizes all rights and responsibilities within the framework of medical treatment for German citizens and legal residents. This comprises the right to informed decisions, comprehensive and comprehensible information for patients, and decisions based on a clinician-patient-partnership. What is the current state of SDM interventions and patient decision support tools? SDM training programs for healthcare professionals have been developed. Their implementation in medical schools has been successful. Several decision support tools - primarily with support from health insurance funds and other public agencies - are to be implemented in routine care, specifically for national cancer screening programs. What is the current state of research and routine implementation? The German government and other public institutions are constantly funding research programs in which patient-centered care and shared decision-making are important topics. The development and implementation of decision tools for patients and professionals as well as the implementation of CME trainings for healthcare professionals require future efforts. What does the future look like? With the support of health policy and scientific evidence, transfer of PCC and SDM to practice is regarded as meaningful. Research can help to assess barriers, facilitators, and needs, and subsequently to develop and evaluate corresponding strategies to successfully implement PCC and SDM in routine care, which remains challenging.}, language = {en} } @article{KnoedlerBerkinMoogetal., author = {Kn{\"o}dler, Leonard and Berkin, {\"O}zdemir and Moog, Philipp and Prantl, Lukas and Broer, P. Niclas and Kn{\"o}dler, Christoph and Rieger, Ulrich M. and Perl, Markus and von Isenburg, Sarah and Gassner, Ulrich M. and Obed, Doha and Haug, Valentin and Panayi, Adriana C. and Knoedler, Samuel}, title = {Thinking like a Lawyer - Human Rights and Their Association with the Plastic Surgeon of Today}, series = {Aesthetic Plastic Surgery}, volume = {114}, journal = {Aesthetic Plastic Surgery}, publisher = {Springer-Verlag GmbH}, address = {Heidelberg}, doi = {10.1007/s00266-022-02990-9}, pages = {8}, abstract = {Plastic surgeons are trained to perform a wide repertoire of surgeries-ranging from standard local procedures to highly specialized operations. Therefore, plastic surgeons treat a plethora of clinical presentations and address multiple patient needs. Their daily workflow is increasingly entwined with legal topics. The concrete legal interpretation falls within the remit of legal experts. However, by understanding the legal basics of selected surgical procedures, plastic surgeons may generate synergies in patient care and clinical practice. The legal situation is to be elucidated based on the German Basic Law (GBL) and the European Convention on Human Rights (ECHR).}, language = {en} } @article{KnoedlerKnoedlerKaukeNavarroetal., author = {Kn{\"o}dler, Leonard and Knoedler, Samuel and Kauke-Navarro, Martin and Kn{\"o}dler, Christoph and H{\"o}fer, Simon and B{\"a}cher, Helena and Gassner, Ulrich M. and Machens, Hans-G{\"u}nther and Prantl, Lukas and Panayi, Adriana C.}, title = {Three-dimensional Medical Printing and Associated Legal Issues in Plastic Surgery: A Scoping Review}, series = {Plastic \& Reconstructive Surgery-Global Open}, volume = {11}, journal = {Plastic \& Reconstructive Surgery-Global Open}, number = {4}, publisher = {Wolters Kluwer}, issn = {2169-7574}, doi = {10.1097/GOX.0000000000004965}, abstract = {Three-dimensional printing (3DP) represents an emerging field of surgery. 3DP can facilitate the plastic surgeon's workflow, including preoperative planning, intraoperative assistance, and postoperative follow-up. The broad clinical application spectrum stands in contrast to the paucity of research on the legal framework of 3DP. This imbalance poses a potential risk for medical malpractice lawsuits. To address this knowledge gap, we aimed to summarize the current body of legal literature on medical 3DP in the US legal system. By combining the promising clinical use of 3DP with its current legal regulations, plastic surgeons can enhance patient safety and outcomes.}, language = {en} } @misc{HaugLauerMeusslingSentpalietal., author = {Haug, Sonja and Lauer, Norina and Meussling-Sentpali, Annette and Mohr, Christa and Pfingsten, Andrea and Raptis, Georgios and Weber, Karsten and Bahr, Gudrun and Currle, Edda and Ettl, Katrin and Frommeld, Debora and Greiner, Nina and Kudienko, Natalie and Lichtenauer, Norbert and Middel, Luise and M{\"u}cke, Vanessa and Popp, Christof}, title = {Telepr{\"a}senzroboter f{\"u}r die Pflege und Unterst{\"u}tzung von Schlaganfallpatinnen und -patienten (TePUS)}, series = {Virtuelle Tagung "DeinHaus 4.0 Oberpfalz", 2020, Ostbayerische Technische Hochschule Regensburg}, journal = {Virtuelle Tagung "DeinHaus 4.0 Oberpfalz", 2020, Ostbayerische Technische Hochschule Regensburg}, language = {de} } @misc{HaugSchmidbauer, author = {Haug, Sonja and Schmidbauer, Simon}, title = {Erhebungsmaterialien im Projekt Demokratieakzeptanz und Partizipation von Gefl{\"u}chteten (DePaGe)}, organization = {Ostbayerische Technische Hochschule Regensburg / Institut f{\"u}r Sozialforschung und Technikfolgenabsch{\"a}tzung}, doi = {10.35096/othr/pub-7729}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-77296}, abstract = {Erhebungsmaterialien (Fragebogen und Informationstext) des Forschungsprojekts Demokratieakzeptanz und Partizipation von Gefl{\"u}chteten (DePaGe) im Rahmen des bayerischen Forschungsverbunds zur Zukunft der Demokratie (ForDemocracy).}, language = {de} } @incollection{Pfingsten, author = {Pfingsten, Andrea}, title = {Telepr{\"a}senzroboter - Potenzial als Unterst{\"u}tzung von Pflege und Therapie}, series = {Digitale Technik f{\"u}r ambulante Pflege und Therapie III: Nutzung Akzeptanz Wirkung und Lebensqualit{\"a}t}, booktitle = {Digitale Technik f{\"u}r ambulante Pflege und Therapie III: Nutzung Akzeptanz Wirkung und Lebensqualit{\"a}t}, editor = {Weber, Karsten and Haug, Sonja and Lauer, Norina and Mohr, Christa}, publisher = {transcript}, address = {Bielefeld}, isbn = {978-3-8376-6728-8}, doi = {10.14361/9783839467282-002}, url = {http://nbn-resolving.de/10.14361/9783839467282-002}, pages = {7 -- 12}, language = {de} } @article{RoehrlStauferBugertetal., author = {R{\"o}hrl, Simon and Staufer, Susanne and Bugert, Flemming and Nadimpalli, Vamsi Krishna and Hauser, Florian and Grabinger, Lisa and Bittner, Dominik and Ezer, Timur and Altweck, Ricardo and Graf, Sabine and Kriza, Thomas and Mottok, J{\"u}rgen}, title = {Ethical Considerations of AI in Education: A Case Study based on Pythia Learning Enhancement System}, series = {IEEE Access}, volume = {11}, journal = {IEEE Access}, publisher = {Institute of Electrical and Electronics Engineers (IEEE)}, issn = {2169-3536}, doi = {10.1109/ACCESS.2025.3583975}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:898-opus4-83403}, pages = {1 -- 25}, abstract = {As the use of AI in education increases, addressing ethical concerns is essential for its responsible use and implementation. This study explores the ethical considerations of AI in education by analyzing a concrete application, the Pythia Learning Enhancement System, which enables personalized and adaptive educational experiences. In this case study, the concrete implementation of Pythia, contrary to high-level abstract analyses, provides practical insights into these ethical issues. To achieve this goal, we first define Pythia and outline its implementation. Using the various topics covered by Pythia, the ethical issues associated with each of these topics are outlined, resulting in a list of ten distinct ethical issues. Because there is overlap in issues covered by similar applications, they can benefit from this identification. An ethical (human rights) and didactic (constructivism) theoretical background is then provided as a basis for further discussion. This is used to build the arguments used in the main study. This consists of analyzing each of the issues and providing recommendations to mitigate potential harm arising from these issues. This helps to provide guidelines for future applications. In the analysis, the ethical discussion is mainly based on the human rights of the stakeholders involved, emphasizing human dignity. After the analysis, each of the issues is contextualized with the recent AI Act of the European Union, providing a novel mapping of the issues of AI in education to the AI Act. Finally, the limitations of the study are stated and a plan for future research is presented.}, language = {en} } @techreport{KunhardtZerthEberletal., author = {Kunhardt, Horst and Zerth, J{\"u}rgen and Eberl, Inge and Flemming, Daniel and Hilbert, Josef and Weber, Karsten and Kohls, Niko and Rester, David and Engel, Lars and Engel, Christian}, title = {Hochschulinitiative f{\"u}r eine personenzentrierte und nachhaltige Gestaltung von Technik und Digitalisierung in der Pflege - Wege von der Anwendungsforschung zur Implementierung und Evaluierung in der Praxis und Lebenswelt}, doi = {10.13140/RG.2.2.32095.64160}, abstract = {The professors from universities and universities of applied sciences and their educational partners who support this initiative are all joined by a research agenda and a sense of responsibility, according to which it is essential for applied research to further explore the effects of technological assistance systems and digital solutions in and for realistic settings with theoretically and methodologically sound and scientific support, based on the highest possible level of evidence, and to make a contribution to evidence-based translation and transferability to society.}, language = {mul} } @book{DehlingerBanarjeeBaurMelnyketal., author = {Dehlinger, Friedrich and Banarjee, M. and Baur-Melnyk, A. and Berth, A. and B{\"o}keler, Ulf W. and Brandt, Hanna and Brunnader, Lars and B{\"u}ttner, Carl Christopher and Clausen, J. and Eden, Lars and Englert, Carsten and Freislederer, F. and Grimm, C. and Grossmann, Irmgard and Jung, C. and Kopkow, Christian and Krifter, R.M. and Martetschl{\"a}ger, Frank and Mehrens, D. and Michalk, Katrin and M{\"u}ller-Rath, Ralf and Pfingsten, Andrea and Prill, Robert and Schmalzl, J. and W{\"o}rtler, K.}, title = {Schultersteife : eine S2e Leitlinie der Deutschen Gesellschaft f{\"u}r Orthop{\"a}die und Unfallchirurgie e.V. (DGOU) mit Beteiligung der Deutsche Vereinigung f{\"u}r Schulter- und Ellenbogenchirurgie e.V. (DVSE)}, edition = {Version 1.0}, publisher = {AWMF online}, address = {Berlin}, pages = {69}, abstract = {Bei der Schultersteife handelt es sich um ein h{\"a}ufiges Krankheitsbild in der Orthop{\"a}die bzw. Schulterchirurgie, das sowohl bei {\"A}rztinnen und {\"A}rzten (Allgemeinmedizinerinnen und mediziner, Fach{\"a}rztinnen und -{\"a}rzte) als auch bei sonstigem medizinischem Fachpersonal, z.B. der Physiotherapie oder Pflege, nur einen geringen Bekanntheitsgrad besitzt. Zielorientierung dieser Leitlinie war es, eine fundierte Hilfestellung und Richtlinie in Bezug auf das Krankheitsbild f{\"u}r {\"A}rztinnen, {\"A}rzte und medizinisches Fachpersonal zu schaffen, den aktuellen evidenz-basierten Wissensstand zu vermitteln und eine bessere Patientinnen- und Patientenversorgung zu erzielen, inkl. der intensiven Aufkl{\"a}rung der Betroffenen durch die behandelnden Berufsgruppen und - wenn von den Betroffenen gew{\"u}nscht - einer gemeinsamen Entscheidungsfindung bez{\"u}glich der Behandlung.}, language = {de} } @article{NiedlingRichterHaemel, author = {Niedling, Katharina and Richter, Stefanie and H{\"a}mel, Kerstin}, title = {Triadic relationships in home care nursing: an integrative review of the views and experiences of older couples and nurses}, series = {BMC nursing}, volume = {24}, journal = {BMC nursing}, publisher = {BMC}, doi = {10.1186/s12912-025-03378-1}, pages = {13}, abstract = {BACKGROUND The need for long-term home care for older people with chronic health conditions is rising, and family members are bearing the brunt of this care work. Caring for a partner is a common scenario. Caregiving partners are often of advanced age themselves and have limiting health conditions of their own. Nurses need to consider the specific characteristics of partner caregiving to provide relationship-centred care. This review aims to analyse perceptions of the triadic relationship between older persons with long-term care needs, their caregiving partners and nurses and to identify approaches that can be supportive approaches that can help couples to cope with at-home care situations. METHODS This integrative review following the method outlined by Whittemore and Knafl focuses on qualitative and mixed methods studies. A systematic search in the PubMed and CINAHL databases served to identify studies dealing with experiences and perceptions of triadic care arrangements in home-based care from the perspectives of nurses, care recipients and caregiving partners. Eight studies met the inclusion criteria and investigated perceptions of the triadic relationship between nurses providing home care and older couples. They were analysed using thematic analysis. RESULTS The results show that triadic relationships in home-based care are shaped by social dynamics, role conflicts and barriers to communication. Although many couples are initially reluctant to integrate nursing professionals into home caregiving, mutual trust can develop when personnel continuity is given and sustained relationship work is performed. Clear communication, clarity on the distribution of tasks and proactive knowledge sharing by nurses facilitate cooperation. Caregiving partners desire support with self-care to preserve their ability to continue in their caregiving roles in the long term. CONCLUSIONS Understanding the dynamics of triadic relationships in nursing care and the care situation in couple relationships enables nurses to provide more targeted support to older couples. Proactive communication, role clarity and continuity of care can reduce the burden shouldered by caregiving partners and improve care quality. Further research focusing on strategies for strengthening relationship-centred interventions in home-based care is desirable. CLINICAL TRIAL NUMBER Not applicable.}, language = {en} } @incollection{BoppMichelBrandtetal., author = {Bopp, Katharina and Michel, Natalie and Brandt, Hanna and Maric, Fillip and Pfingsten, Andrea}, title = {Die Komplexit{\"a}t nachhaltiger Physiotherapie}, series = {Die Nachhaltigkeitsziele der UN im Spiegel der Wissenschaft: Beispiele aus der Sozial- und Gesundheitsforschung}, booktitle = {Die Nachhaltigkeitsziele der UN im Spiegel der Wissenschaft: Beispiele aus der Sozial- und Gesundheitsforschung}, editor = {Heese, Carl and Sch{\"u}tz, Sandra and Obergrießer, Stefanie}, edition = {1. Aufl.}, publisher = {Springer Nature}, address = {Wiesbaden}, isbn = {978-3-658-43333-8}, doi = {10.1007/978-3-658-43334-5_15}, pages = {247 -- 269}, abstract = {Um m{\"o}gliche Forschungsperspektiven in Bezug auf die UN-Nachhaltigkeitsziele 3 (Gesundheit und Wohlergehen) und 13 (Maßnahmen zum Klimaschutz) aufzeigen zu k{\"o}nnen, stellten sich die Autor*innen dieses Beitrags die Frage, wie Physiotherapie langfristig Nachhaltigkeit f{\"o}rdern kann und was es daf{\"u}r in der Versorgung braucht. Wie Physiotherapeut*innen ihre Therapie nachhaltig gestalten k{\"o}nnen wurde mit Teilnehmenden des Workshops Planetare Gesundheit auf dem 6. Forschungssymposium der Deutschen Gesellschaft f{\"u}r Physiotherapiewissenschaft (DGPTW) in Freiburg diskutiert. Dabei stellte sich heraus, dass sich die Physiotherapeut*innen neben dem Wie? vor allem die Frage nach dem Warum (wir)? stellten und angaben unsicher mit dem Thema Klimawandel in der Behandlung zu sein. Daraus wurden zwei Schwerpunktthemen abgeleitet, welche in diesem Beitrag ausgearbeitet werden. 1) Emotionalit{\"a}t im professionellen Handeln: Wie Professionalit{\"a}t die richtigen Emotionen zur Bew{\"a}ltigung der heutigen Krisen f{\"o}rdern kann und 2) Komplexe Entscheidungsprozesse f{\"o}rdern - ‚sustainable decision-making' am Beispiel der Teletherapie. Aus den Ausarbeitungen kann geschlossen werden, dass Physiotherapie in ihrer Komplexit{\"a}t zunehmen wird, wenn sie nachhaltig sein soll, weil sie vielf{\"a}ltige Probleme ber{\"u}cksichtigen muss. Daf{\"u}r braucht es qualifizierte Physiotherapeut*innen, die bef{\"a}higt und bem{\"a}chtigt sind, die komplexen Anforderungen zu bew{\"a}ltigen.}, language = {de} } @article{EnglertAngeleFierlbecketal., author = {Englert, Carsten and Angele, Peter and Fierlbeck, J. and Dendorfer, Sebastian and Schubert, T. and M{\"u}ller, R. and Lienhard, S. and Zellner, Johannes and Nerlich, Michael and Neumann, Carsten}, title = {Conductive bone substitute material with variable antibiotic delivery}, series = {Der Unfallchirurg}, volume = {110}, journal = {Der Unfallchirurg}, number = {5}, publisher = {Springer}, doi = {10.1007/s00113-007-1229-3}, pages = {408 -- 413}, abstract = {A new bone substitute, consisting of hydroxylapatite and calcium sulphate, was prepared in two formulations and analysed for its mechanical strength and antibiotic elution.The bone substitute PerOssal has osteoconductive and degradable properties. The material has a built-in capillary structure, which results in an immediate fluid uptake. Antibiotics absorbed to the bone substitute resulted in a prolonged release rate. Mechanical strength was investigated by an unconfined compression test up to failure under both wet and dry conditions for both formulations of the bone substitute. Antibiotic release was analysed microbiologically for two antibiotics, vancomycin and gentamicin, over an elution period of 10 days using the agar diffusion method.The drug release analysis resulted in a prolonged release rate of both antibiotics over 10 days. In vitro the amount of gentamicin and vancomycin eluted at day 10. From one pellet still exceeded the minimal inhibitory concentration of most aetiologically important pathogens. Formulation two of the present bone substitute is significantly harder in both wet and dry conditions when compared to formulation one. Both formulations lose strength in the wet condition relative to their performance in the dry condition. However, formulation two is as hard under wet conditions as formulation one is when dry.PerOssal is a suitable new degradable osteoconductive bone substitute that can be loaded with antibiotic solutions, which are released in effective doses over 10 days. The mechanical strength of PerOssal is sufficient to support cancellous bone defects in non-weight-bearing areas or in combination with osteosynthesis.}, subject = {Knochenersatz}, language = {en} } @incollection{ChristenGordijnWeberetal., author = {Christen, Markus and Gordijn, Bert and Weber, Karsten and van de Poel, Ibo and Yaghmaei, Emad}, title = {A review of value-conflicts in cybersecurity}, series = {Bezpieczeństwo informacyjne w wymiarze systemowym}, booktitle = {Bezpieczeństwo informacyjne w wymiarze systemowym}, editor = {Oleksiewicz, Izabela}, publisher = {Rambler Press}, address = {Warszawa}, pages = {67 -- 92}, abstract = {The growing complexity of the digital ecosystem in combination with increasing global risks has created the following dilemma. Overemphasizing cybersecurity may violate fundamental values like equality, fairness, freedom, or privacy but neglecting cybersecurity could undermine citizens' trust and confidence in the digital infrastructure as well as in policy makers and state authorities. In order to increase our understanding of this dilemma, this contribution aims to provide an overview on value conflicts in cybersecurity based on a systematic review on the ethical, legal and technological literature on cybersecurity. It shall be emphasized that a focus on the opposition of cybersecurity vs. privacy is insufficient for understanding the ethical complexity of cybersecurity.}, subject = {Computersicherheit}, language = {en} } @misc{HaugLauerMeusslingSentpalietal., author = {Haug, Sonja and Lauer, Norina and Meussling-Sentpali, Annette and Mohr, Christa and Pfingsten, Andrea and Raptis, Georgios and Weber, Karsten and Bahr, Gudrun and Currle, Edda and Ettl, Katrin and Frommeld, Debora and Greiner, Nina and Kudienko, Natalie and Lichtenauer, Norbert and Middel, Luise and M{\"u}cke, Vanessa and Popp, Christof}, title = {TePUS - Telepr{\"a}senzroboter f{\"u}r die Pflege}, series = {TRIOKON 2020 : Wissenschaft, Wirtschaft, Gesellschaft in Ostbayern, 29.09.2019, Landshut}, journal = {TRIOKON 2020 : Wissenschaft, Wirtschaft, Gesellschaft in Ostbayern, 29.09.2019, Landshut}, language = {de} } @misc{SchmidbauerRohrerHaug, author = {Schmidbauer, Simon and Rohrer, Ricarda and Haug, Sonja}, title = {Politische Beteiligungsm{\"o}glichkeiten von Migrant*innen in Deutschland - Handreichung f{\"u}r Multiplikator*innen}, doi = {10.13140/RG.2.2.33297.30568}, abstract = {Begleittext zum Poster Politische Beteiligungsm{\"o}glichkeiten von Migrant*innen in Deutschland im Rahmen des Projekts "Demokratieakzeptanz und Partizipation von Gefl{\"u}chteten (DePaGe) im Bayerischen Forschungsverbund ForDemocracy}, language = {de} } @article{SteigerFoltanPhilippetal., author = {Steiger, Tamara and Foltan, Maik and Philipp, Alois and M{\"u}ller, Thomas and Gruber, Michael and Bredthauer, Andre and Krenkel, Lars and Birkenmaier, Clemens and Lehle, Karla}, title = {Accumulations of von Willebrand factor within ECMO oxygenators: Potential indicator of coagulation abnormalities in critically ill patients?}, series = {Artificial Organs}, volume = {43}, journal = {Artificial Organs}, number = {11}, publisher = {Wiley}, address = {Hoboken}, issn = {1525-1594}, doi = {10.1111/aor.13513}, pages = {1065 -- 1076}, abstract = {Clot formation within membrane oxygenators (MOs) remains a critical problem during extracorporeal membrane oxygenation (ECMO). The composition of the clots-in particular, the presence of von Willebrand factor (vWF)-may be an indicator for prevalent nonphysiological flow conditions, foreign body reactions, or coagulation abnormalities in critically ill patients. Mats of interwoven gas exchange fibers from randomly collected MOs (PLS, Maquet, Rastatt, Germany) of 21 patients were stained with antibodies (anti-vWF and anti-P-selectin) and counterstained with 4 ',6-diamidino-2-phenylindole. The extent of vWF-loading was correlated with patient and technical data. While 12 MOs showed low vWF-loadings, 9 MOs showed high vWF-loading with highest accumulations close to crossing points of adjacent gas fibers. The presence and the extent of vWF-fibers/"cobwebs," leukocytes, platelet-leukocyte aggregates (PLAs), and P-selectin-positive platelet aggregates were independent of the extent of vWF-loading. However, the highly loaded MOs were obtained from patients with a significantly elevated SOFA score, severe thrombocytopenia, and persistent liver dysfunction. The coagulation abnormalities of these critically ill patients may cause an accumulation of the highly thrombogenic and elongated high-molecular-weight vWF multimers in the plasma which will be trapped in the MOs during the ECMO therapy.}, language = {en} } @article{KnoedlerDeanKnoedleretal., author = {Kn{\"o}dler, Leonard and Dean, Jillian and Knoedler, Samuel and Kauke-Navarro, Martin and Hollmann, Katharina and Alfertshofer, Michael and Helm, Sabrina and Prantl, Lukas and Schliermann, Rainer}, title = {Hard shell, soft core? Multi-disciplinary and multi-national insights into mental toughness among surgeons}, series = {Frontiers in Surgery}, volume = {11}, journal = {Frontiers in Surgery}, publisher = {Frontiers}, doi = {10.3389/fsurg.2024.1361406}, pages = {7}, abstract = {Background: With the prevalence of burnout among surgeons posing a significant threat to healthcare outcomes, the mental toughness of medical professionals has come to the fore. Mental toughness is pivotal for surgical performance and patient safety, yet research into its dynamics within a global and multi-specialty context remains scarce. This study aims to elucidate the factors contributing to mental toughness among surgeons and to understand how it correlates with surgical outcomes and personal well-being. Methods: Utilizing a cross-sectional design, this study surveyed 104 surgeons from English and German-speaking countries using the Mental Toughness Questionnaire (MTQ-18) along with additional queries about their surgical practice and general life satisfaction. Descriptive and inferential statistical analyses were applied to investigate the variations in mental toughness across different surgical domains and its correlation with professional and personal factors. Results: The study found a statistically significant higher level of mental toughness in micro-surgeons compared to macro-surgeons and a positive correlation between mental toughness and surgeons' intent to continue their careers. A strong association was also observed between general life satisfaction and mental toughness. No significant correlations were found between the application of psychological skills and mental toughness. Conclusion: Mental toughness varies significantly among surgeons from different specialties and is influenced by professional dedication and personal life satisfaction. These findings suggest the need for targeted interventions to foster mental toughness in the surgical community, potentially enhancing surgical performance and reducing burnout. Future research should continue to explore these correlations, with an emphasis on longitudinal data and the development of resilience-building programs.}, language = {en} } @article{WalterSchmidtKoerkel, author = {Walter, Sebastian F. and Schmidt, Andreas and K{\"o}rkel, Stefan}, title = {Adjoint-based optimization of experimental designs with many control variables}, series = {Journal of Process Control}, volume = {24}, journal = {Journal of Process Control}, number = {10}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0959-1524}, doi = {10.1016/j.jprocont.2014.06.019}, pages = {1504 -- 1515}, abstract = {We propose a method for an efficient optimization of experimental designs, using a combination of discrete adjoint computations, Taylor arithmetic and matrix calculus. Compared to the state of the art of using finite differences or the forward mode of automatic differentiation, our proposed approach leads to a reduction of the relative temporal complexity from linear to constant time in the number of control variables and measurement weights. We demonstrate that the advantageous complexity results are not only of theoretical nature, but lead to significant speedups in practice as well. With our implementation we are very close to the theoretical bound of the cheap gradient principle. We present one academic (spatially discretized heat equation) and two industrial application examples (biochemical process/Diesel-oxidation catalysis process) where we achieve speedups that range between 10 and 100. In addition to our core results, we also describe an efficient adjoint approach for the treatment of differential algebraic equations and present adjoint formulas for constrained least-squares problems.}, language = {de} } @misc{KrenkelMichelKeiletal., author = {Krenkel, Lars and Michel, Johanna and Keil, Niklas and Daschner, Jan}, title = {Experimental Investigation of Logitudinal Folds in Endotracheal Tube Cuffs and their Correlation to Silent Breathing}, series = {23. DGLR Fach-Symposium Str{\"o}mungen mit Abl{\"o}sung, 09./10. November 2022, Berlin, Deutschland}, journal = {23. DGLR Fach-Symposium Str{\"o}mungen mit Abl{\"o}sung, 09./10. November 2022, Berlin, Deutschland}, address = {G{\"o}ttingen}, organization = {Deutsche Gesellschaft f{\"u}r Luft- und Raumfahrt e.V. / Arbeitsgemeinschaft Str{\"o}mungen mit Abl{\"o}sung, AG STAB}, abstract = {Air leakage past High-Volume-Low-Pressure (HVLP) endotracheal tube (ETT) cuffs creates a potential infection risk for health care professionals during ventilation of patients suffering from contagious airborne diseases. However, unlike silent aspiration, a phenomenon where fluids enter the airways of intubated patients, the aspect of aerosol emergence through cuff folds -what we called accordingly "silent breathing" (SB)- has not been investigated in detail so far. This study investigates air leakage past HVLP cuffs with varying cuff pressures under realistic artificial breathing scenarios experimentally and in addition numerically. The focus was laid on the parametric investigation of the occurrence and furthermore on different influencing factors of silent breathing. The morphology of the folds responsible for the leakage was captured using high-resolution 3D microcomputed tomography (μCT). For the numerical investigations (Com-putational Fluid Dynamics - CFD), the commercial CFD Software package FLUENT 2021 R2 (ANSYS, Inc., Canonsburg, PA, US), as well as the DLR in-house research code THETA has been used.}, language = {en} } @incollection{HeeseSteinSchmidt, author = {Heese, Carl and Stein, Margit and Schmidt, Hans-Ludwig}, title = {Zielorientierung als Merkmal intelligenter Praxis und als transdisziplin{\"a}re und therapieintegrierende Einstellung}, series = {Patientenorientierte Versorgung im Team - POVIT}, booktitle = {Patientenorientierte Versorgung im Team - POVIT}, editor = {Heese, Carl and Schmidt, Hans-Ludwig and Preger, Rudolf}, publisher = {BPB-Verlag diritto Publikationen}, address = {Eichst{\"a}tt}, isbn = {3-927728-61-6}, pages = {39 -- 48}, language = {de} } @techreport{HeeseSchmidtPreger, author = {Heese, Carl and Schmidt, Hans-Ludwig and Preger, Rudolf}, title = {Patientenorientierte Versorgung im Team - POVIT}, publisher = {BPB}, address = {Eichst{\"a}tt}, isbn = {3-927728-61-6}, pages = {160}, language = {de} } @incollection{HeeseSteinSchmidt, author = {Heese, Carl and Stein, Margit and Schmidt, Hans-Ludwig}, title = {Das Kipfenberger Team-Controlling: Ein Instrument der Teamentwicklung und Qualit{\"a}tssicherung}, series = {Patientenorientierte Versorgung im Team}, booktitle = {Patientenorientierte Versorgung im Team}, editor = {Heese, Carl and Schmidt, Hans-Ludwig and Preger, Rudolf}, publisher = {BPB}, address = {Eichst{\"a}tt}, pages = {83 -- 98}, language = {de} } @incollection{Heese, author = {Heese, Carl}, title = {Das Goal-Attainment-Scaling (GAS) in der Rehabilitation}, editor = {Heese, Carl and Schmidt, Hans-Ludwig and Preger, Rudolf}, publisher = {BPB}, address = {Eichst{\"a}tt}, pages = {49 -- 82}, language = {de} }