@misc{AuerReinkerSuessetal., author = {Auer, Simon and Reinker, Lukas and S{\"u}ß, Franz and Dendorfer, Sebastian}, title = {Comparing calculated and measured muscle activity of thigh muscles in dynamic motion.}, series = {27th Congress of the European Society of Biomechanics, 26 - 29 June 2022, Porto, Portugal}, journal = {27th Congress of the European Society of Biomechanics, 26 - 29 June 2022, Porto, Portugal}, pages = {640}, language = {en} } @misc{MelznerPfeiferSuessetal., author = {Melzner, Maximilian and Pfeifer, Christian and S{\"u}ß, Franz and Dendorfer, Sebastian}, title = {Muskuloskeletal analysis of elbow stability for common injury patterns}, series = {27th Congress of the European Society of Biomechanics, 26 - 29 June 2022, Porto, Portugal}, journal = {27th Congress of the European Society of Biomechanics, 26 - 29 June 2022, Porto, Portugal}, pages = {654}, language = {en} } @misc{KoeglerIsmailRusavyetal., author = {K{\"o}gler, Michael and Ismail, Khaled M. and Rusavy, Zdenek and Kalis, Vladimir and S{\"u}ß, Franz and Dendorfer, Sebastian}, title = {Influence of bed height and stance on accoucheurs lower back and glenohumeral load during simulated childbirth}, series = {31st meeting of Czech Urogynaecological Society, Prague, 2022}, journal = {31st meeting of Czech Urogynaecological Society, Prague, 2022}, language = {en} } @misc{PfingstenBorgettoTomlinetal., author = {Pfingsten, Andrea and Borgetto, Bernhard and Tomlin, George S. and Max, Susanne and Trickes, Claudia}, title = {The Research Pyramid. Establishing the value of evidence from multiple research approaches in a systematic review}, series = {World Physical Therapy Congress der World Confederation for Physical Therapy (WCPT), Amsterdam, 2011}, journal = {World Physical Therapy Congress der World Confederation for Physical Therapy (WCPT), Amsterdam, 2011}, abstract = {Goal: The Research Pyramid is a model that values and integrates external evidence from multiple research approaches: experimental and observational as well as quantitative and qualitative. It provides a basis to collect and synthesize research findings for answering questions that emerge in therapy practice and for subsequent decision making, based on research evidence.}, language = {en} } @misc{AltenbuchnerHaugMohretal., author = {Altenbuchner, Amelie and Haug, Sonja and Mohr, Christa and Scorna, Ulrike and Weber, Karsten}, title = {The impact of nurse advisors and online advice services on treatment adherence in multiple sclerosis (MS)}, series = {7th Joint European Committee for Treatment and Research in Multiple Sclerosis - Americas Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS-ACTRIMS), 25.-27.10.2017, Paris}, journal = {7th Joint European Committee for Treatment and Research in Multiple Sclerosis - Americas Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS-ACTRIMS), 25.-27.10.2017, Paris}, language = {en} } @techreport{PfingstenBorgetto, author = {Pfingsten, Andrea and Borgetto, Bernhard}, title = {Efficacy and effectiveness of physical therapy in adults with rheumatoid arthritis}, edition = {Version: 14.05.2020}, abstract = {What is the efficacy of physical therapy in the treatment of rheumatoid arthritis? What is the effectiveness of physical therapy in the treatment of rheumatoid arthritis? Which differences do exist between efficacy and effectiveness of rheumatoid arthritis?}, language = {en} } @article{MuehlingSandriesserDendorferetal., author = {M{\"u}hling, Mischa and Sandriesser, Sabrina and Dendorfer, Sebastian and Augat, Peter}, title = {Assessment of implant internal stresses under physiological femoral loading: Translation to a simplified bending load model}, series = {Journal of Biomechanics}, journal = {Journal of Biomechanics}, number = {112229}, publisher = {Elsevier}, issn = {1873-2380}, doi = {10.1016/j.jbiomech.2024.112229}, pages = {17}, abstract = {The success of surgical treatment for fractures hinges on various factors, notably accurate surgical indication. The process of developing and certifying a new osteosynthesis device is a lengthy and costly process that requires multiple cycles of review and validation. Current methods, however, often rely on predecessor standards rather than physiological loads in specific anatomical locations. This study aimed to determine actual loads experienced by an osteosynthesis plate, exemplified by a standard locking plate for the femoral shaft, utilizing finite elements analysis (FEA) and to obtain the bending moments for implant development standard tests. A protocol was developed, involving the creation and validation of a fractured femur model fixed with a locking plate, mechanical testing, and FEA. The model's validation demonstrated exceptional accuracy in predicting deformations, and the FEA revealed peak stresses in the fracture bridging zone. Results of a parametric analysis indicate that larger fracture gaps significantly impact implant mechanical behavior, potentially compromising stability. This study underscores the critical need for realistic physiological conditions in implant evaluations, providing an innovative translational approach to identify internal loads and optimize implant designs. In conclusion, this research contributes to enhancing the understanding of implant performance under physiological conditions, promoting improved designs and evaluations in fracture treatments.}, language = {en} } @article{RusavyCechovaDendorferetal., author = {Rusavy, Zdenek and Cechova, Hana and Dendorfer, Sebastian and Kalis, Vladimir and Ismail, Khaled M.}, title = {Is the Finnish grip tight enough? A manometric study of two manual perineal protection techniques}, series = {Acta Obstetricia et Gynecologica Scandinavica}, journal = {Acta Obstetricia et Gynecologica Scandinavica}, edition = {Early view}, publisher = {Wiley}, doi = {10.1111/aogs.15033}, language = {en} } @article{MelznerSuessDendorfer, author = {Melzner, Maximilian and Suess, Franz and Dendorfer, Sebastian}, title = {The impact of anatomical uncertainties on the predictions of a musculoskeletal hand model - a sensitivity study}, series = {Computer Methods in Biomechanics and Biomedical Engineering}, volume = {25}, journal = {Computer Methods in Biomechanics and Biomedical Engineering}, number = {2}, publisher = {Taylor \& Francis}, issn = {1476-8259}, doi = {10.1080/10255842.2021.1940974}, pages = {156 -- 164}, abstract = {Outputs of musculoskeletal models should be considered probabilistic rather than deterministic as they are affected by inaccuracies and estimations associated with the development of the model. One of these uncertainties being critical for modeling arises from the determination of the muscles' line of action and the physiological cross-sectional area. Therefore, the aim of this study was to evaluate the outcome sensitivity of model predictions from a musculoskeletal hand model in comparison to the uncertainty of these input parameters. For this purpose, the kinematics and muscle activities of different hand movements (abduction of the fingers, abduction of the thumb, and flexion of the thumb) were recorded. One thousand simulations were calculated for each movement using the Latin hypercube sampling method with a corresponding variation of the muscle origin/insertion points and the cross-sectional area. Comparing the standard hand to simulations incorporating uncertainties of input parameters shows no major deviations in on- and off-set time point of muscle activities. About 60\% of simulations are located within a ± 30\% interval around the standard model concerning joint reaction forces. The comparison with the variation of the input data leads to the conclusion that the standard hand model is able to provide not over-scattered outcomes and, therefore, can be considered relatively stable. These results are of practical importance to the personalization of a musculoskeletal model with subject-specific bone geometries and hence changed muscle line of action.}, subject = {Biomechanik}, language = {en} } @article{MelznerEngelhardtSimonetal., author = {Melzner, Maximilian and Engelhardt, Lucas and Simon, Ulrich and Dendorfer, Sebastian}, title = {Electromyography-Based Validation of a Musculoskeletal Hand Model}, series = {Journal of Biomechanical Engineering}, volume = {144}, journal = {Journal of Biomechanical Engineering}, number = {2}, publisher = {American Society of Mechanical Engineers, ASME}, doi = {10.1115/1.4052115}, pages = {8}, abstract = {Regarding the prevention of injuries and rehabilitation of the human hand, musculoskeletal simulations using an inverse dynamics approach allow for insights of the muscle recruitment and thus acting forces on the hand. Currently, several hand models from various research groups are in use, which are mainly validated by the comparison of numerical and anatomical moment arms. In contrast to this validation and model-building technique by cadaver studies, the aim of this study is to further validate a recently published hand model [1] by analyzing numerically calculated muscle activities in comparison to experimentally measured electromyographical signals of the muscles. Therefore, the electromyographical signals of 10 hand muscles of five test subjects performing seven different hand movements were measured. The kinematics of these tasks were used as input for the hand model, and the numerical muscle activities were computed. To analyze the relationship between simulated and measured activities, the time difference of the muscle on- and off-set points was calculated, which resulted in a mean on- and off-set time difference of 0.58 s between the experimental data and the model. The largest differences were detected for movements that mainly addressed the wrist. One major issue comparing simulated and measured muscle activities of the hand is cross-talk. Nevertheless, the results show that the hand model fits the experiment quite accurately despite some limitations and is a further step toward patient-specific modeling of the upper extremity.}, subject = {Elektromyographie}, language = {en} }